KEGG   ORTHOLOGY: K19080
Entry
K19080                      KO                                     
Symbol
vraG
Name
cationic antimicrobial peptide transport system permease protein
Pathway
map01503  Cationic antimicrobial peptide (CAMP) resistance
map02010  ABC transporters
map02020  Two-component system
map05150  Staphylococcus aureus infection
Module
M00730  Cationic antimicrobial peptide (CAMP) resistance, VraFG transporter
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    K19080  vraG; cationic antimicrobial peptide transport system permease protein
  09132 Signal transduction
   02020 Two-component system
    K19080  vraG; cationic antimicrobial peptide transport system permease protein
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    K19080  vraG; cationic antimicrobial peptide transport system permease protein
  09175 Drug resistance: antimicrobial
   01503 Cationic antimicrobial peptide (CAMP) resistance
    K19080  vraG; cationic antimicrobial peptide transport system permease protein
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K19080  vraG; cationic antimicrobial peptide transport system permease protein
   01504 Antimicrobial resistance genes
    K19080  vraG; cationic antimicrobial peptide transport system permease protein
Transporters [BR:ko02000]
 ABC transporters, prokaryotic type
  ABC-2 type and other transporters
   Cationic antimicrobial peptide transporter
    K19080  vraG; cationic antimicrobial peptide transport system permease protein
Antimicrobial resistance genes [BR:ko01504]
 Gene sets
  CAMP resistance modules
   Cationic antimicrobial peptide (CAMP) resistance, VraFG transporter
    K19080  vraG; cationic antimicrobial peptide transport system permease protein
Other DBs
COG: COG0577
TC: 3.A.1.134.7
Genes
SDO: SD1155_06075
SAU: SA0617(vraG)
SAV: SAV0662(vraG)
SAW: SAHV_0659(vraG)
SAH: SaurJH1_0700
SAJ: SaurJH9_0685
SAM: MW0624(vraG)
SAS: SAS0627
SAR: SAR0672
SAC: SACOL0720
SAX: USA300HOU_0683(vraE)
SAA: SAUSA300_0648
SAO: SAOUHSC_00668
SAE: NWMN_0631(vraG)
SAD: SAAV_0624
SUU: M013TW_0649
SUV: SAVC_02940
SUE: SAOV_0696
SUJ: SAA6159_00616(vraG)
SUK: SAA6008_00678
SUC: ECTR2_613
SUT: SAT0131_00732
SUQ: HMPREF0772_12526
SUZ: MS7_0712
SUD: ST398NM01_0740
SUX: SAEMRSA15_05880
SUW: SATW20_07370(vraG)
SUG: SAPIG0740
SUF: SARLGA251_05950(vraG)
SAUA: SAAG_01084
SAUE: RSAU_000638(bceB)
SAUN: SAKOR_00657
SAUS: SA40_0602(vraG)
SAUU: SA957_0617(vraG)
SAUG: SA268_0615(vraG)
SAUZ: SAZ172_0673(vraG)
SAUT: SAI1T1_2005120(vraG)
SAUJ: SAI2T2_1005140(vraG)
SAUK: SAI3T3_1005130(vraG)
SAUQ: SAI4T8_1005120(vraG)
SAUV: SAI7S6_1005130(vraG)
SAUW: SAI5S5_1005090(vraG)
SAUX: SAI6T6_1005100(vraG)
SAUY: SAI8T7_1005130(vraG)
SAUF: X998_0709
SAB: SAB0611
SUY: SA2981_0638(vraG)
SAUB: C248_0746
SAUM: BN843_6630
SAUC: CA347_676
SAUR: SABB_06076
SAUI: AZ30_03460
SAUD: CH52_02455
SAMS: NI36_03320
SUH: SAMSHR1132_06080
SER: SERP0315
SEP: SE_0430
SEPP: SEB_00350
SEPS: DP17_1732
SHA: SH2232(vraG)
SHH: ShL2_02081
SCA: SCA_0305
SLG: SLGD_02163
SLN: SLUG_21360(vraG)
SWA: A284_10025
SPAS: STP1_1746
SCAP: AYP1020_0028(bceB_1)
SSIF: AL483_08325
SCV: A4G25_06150
SHOM: EGX58_02945
SCAR: DWB96_10925
SPIC: SAMEA4384060_2212
SSH: NCTC13712_00626
SSIM: SAMEA4384339_0604(vraG)
SDB: CNQ82_12475
SSAC: I6I31_06055
STAS: HYI43_10355
SDEV: Q2T90_08580
SROT: ML435_03115
 » show all
Reference
PMID:17502406
  Authors
Meehl M, Herbert S, Gotz F, Cheung A
  Title
Interaction of the GraRS two-component system with the VraFG ABC transporter to support vancomycin-intermediate resistance in Staphylococcus aureus.
  Journal
Antimicrob Agents Chemother 51:2679-89 (2007)
DOI:10.1128/AAC.00209-07
  Sequence
[sac:SACOL0720]
Reference
PMID:21986630
  Authors
Yang SJ, Bayer AS, Mishra NN, Meehl M, Ledala N, Yeaman MR, Xiong YQ, Cheung AL
  Title
The Staphylococcus aureus two-component regulatory system, GraRS, senses and confers resistance to selected cationic antimicrobial peptides.
  Journal
Infect Immun 80:74-81 (2012)
DOI:10.1128/IAI.05669-11
  Sequence
[sav:SAV0662] [sac:SACOL0720]
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