KEGG   ORTHOLOGY: K19605
Entry
K19605                      KO                                     

Name
EVC1
Definition
ellis van creveld syndrome protein 1
Pathway
ko04340  Hedgehog signaling pathway
Disease
H00503  Ellis-van Creveld syndrome
H02158  Weyers acrofacial dysostosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    K19605  EVC1; ellis van creveld syndrome protein 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K19605  EVC1; ellis van creveld syndrome protein 1
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Centrosome formation and ciliogenesis proteins
   Other cilium assembly proteins
    K19605  EVC1; ellis van creveld syndrome protein 1
Genes
HSA: 2121(EVC)
PTR: 461097(EVC)
PPS: 100996222(EVC)
GGO: 101138183(EVC)
PON: 100435979(EVC)
NLE: 100595240(EVC)
MCC: 711266(EVC)
MCF: 102129962(EVC)
CSAB: 103246400(EVC)
RRO: 104667569(EVC)
RBB: 108538795(EVC)
CJC: 100415445(EVC)
SBQ: 101032550(EVC)
MMU: 59056(Evc)
MCAL: 110295146(Evc)
MPAH: 110330621(Evc)
RNO: 289712(Evc)
MUN: 110544913(Evc)
CGE: 100771932(Evc)
NGI: 103739552(Evc)
HGL: 101719227(Evc)
CCAN: 109695695(Evc)
OCU: 103345885(EVC)
TUP: 102484433(EVC)
CFA: 611166(EVC)
VVP: 112919688(EVC)
AML: 100470532(EVC)
UMR: 103658344(EVC)
UAH: 113266662(EVC)
ORO: 101362801(EVC)
ELK: 111149104
FCA: 101092515(EVC)
PTG: 102969411(EVC)
PPAD: 109269694(EVC)
AJU: 106982721(EVC)
BTA: 282874(EVC)
BOM: 102271648(EVC) 102273071
BIU: 109560665(EVC)
BBUB: 102389190(EVC)
CHX: 102189937(EVC)
OAS: 101113496(EVC)
SSC: 100620576(EVC)
CFR: 102508548(EVC)
CDK: 105085112(EVC)
BACU: 103014528(EVC)
LVE: 103083610(EVC)
OOR: 101274339(EVC)
DLE: 111171458(EVC)
PCAD: 102981406(EVC)
ECB: 100070005(EVC)
EPZ: 103562776
EAI: 106832487(EVC)
MYB: 102245005(EVC)
MYD: 102773260(EVC)
MNA: 107530086(EVC)
HAI: 109392581(EVC)
DRO: 112316682(EVC)
PALE: 102892696(EVC)
RAY: 107519024(EVC)
MJV: 108400119(EVC)
LAV: 100654876(EVC)
TMU: 101343801
MDO: 100018722(EVC)
SHR: 100921888(EVC)
PCW: 110212260(EVC)
OAA: 103168574(EVC)
GGA: 422851(EVC)
MGP: 100549359
CJO: 107313926(EVC)
NMEL: 110397559(EVC)
APLA: 101791730(EVC)
ACYG: 106035167(EVC)
TGU: 100218032(EVC)
LSR: 110481885(EVC)
SCAN: 103826133(EVC)
GFR: 102033801(EVC)
FAB: 101810416(EVC)
PHI: 102110311(EVC)
PMAJ: 107203086(EVC)
CCAE: 111928472(EVC)
CCW: 104690910(EVC)
ETL: 114061464(EVC)
FPG: 101910491(EVC)
FCH: 102050431(EVC)
CLV: 102089984(EVC)
EGZ: 104123276(EVC)
NNI: 104018035(EVC)
ACUN: 113479256(EVC)
PADL: 103921000(EVC)
AAM: 106498769(EVC)
ASN: 102378917(EVC)
AMJ: 102560015(EVC)
PSS: 102458295(EVC)
CMY: 102948363(EVC)
CPIC: 101948055(EVC)
GJA: 107122650(EVC)
XLA: 108698025(evc.L)
XTR: 100124788(evc)
NPR: 108801820(EVC)
SRX: 107716518(evc)
SANH: 107665621(evc)
SGH: 107575290(evc)
IPU: 108256113(evc)
PHYP: 113528305(evc)
AMEX: 103038006(evc)
EEE: 113574012(evc)
TRU: 494347(evc)
LCO: 104927933(evc)
NCC: 104961960(evc)
MZE: 101477059(evc)
ONL: 100697930(evc)
OLA: 101155188(evc)
XMA: 102237084(evc)
XCO: 114135906(evc)
PRET: 103464958(evc)
CVG: 107097281(evc)
NFU: 107385513(evc)
KMR: 108239827
ALIM: 106518382(evc)
CSEM: 103386251(evc)
POV: 109628933(evc)
LCF: 108884019(evc)
SDU: 111221808(evc)
SLAL: 111648821 111670932(evc)
HCQ: 109522679(evc)
MALB: 109955927(evc)
SASA: 106565206
SALP: 111962444(evc)
ELS: 105016756(evc)
SFM: 108924157(evc)
PKI: 111837698(evc)
LCM: 102351258(EVC)
CMK: 103181107(evc)
RTP: 109921182
BFO: 118414117
SPU: 579422
APLC: 110979945
SKO: 100372579
PCAN: 112564071
MYI: 110459141
NVE: 5508586
EPA: 110238895
ADF: 107353827
AMIL: 114976613
PDAM: 113669052
SPIS: 111335514
 » show all
Reference
  Authors
Ginns EI, Galdzicka M, Elston RC, Song YE, Paul SM, Egeland JA
  Title
Disruption of sonic hedgehog signaling in Ellis-van Creveld dwarfism confers protection against bipolar affective disorder.
  Journal
Mol Psychiatry 20:1212-8 (2015)
DOI:10.1038/mp.2014.118
Reference
  Authors
Pusapati GV, Hughes CE, Dorn KV, Zhang D, Sugianto P, Aravind L, Rohatgi R
  Title
EFCAB7 and IQCE regulate hedgehog signaling by tethering the EVC-EVC2 complex to the base of primary cilia.
  Journal
Dev Cell 28:483-96 (2014)
DOI:10.1016/j.devcel.2014.01.021
  Sequence
[hsa:2121]
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