KEGG   ORTHOLOGY: K20082
Entry
K20082                      KO                                     
Symbol
staMB
Name
O-methyltransferase StaMB [EC:2.1.1.139]
Pathway
map00404  Staurosporine biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00805  Staurosporine biosynthesis, tryptophan => staurosporine
Reaction
R05757  S-adenosyl-L-methionine:3'-demethylstaurosporine O-methyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00404 Staurosporine biosynthesis
    K20082  staMB; O-methyltransferase StaMB
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.139  3'-demethylstaurosporine O-methyltransferase
     K20082  staMB; O-methyltransferase StaMB
Other DBs
GO: 0030793
Genes
DEK: DSLASN_18360
SSOI: I1A49_05025
SRN: A4G23_00556(rebM_1)
SCLF: BB341_29640
SSPO: DDQ41_30660
SPAD: DVK44_01710
SAUH: SU9_001560
SFB: CP974_02880
SPRA: CP972_04230
STRZ: OYE22_17000
STRH: GXP74_22410
ACTQ: OG417_05145
SAQ: Sare_2332
MFEU: H1D33_18670
AG: BAC55218(staMB)
 » show all
Reference
PMID:16164546
  Authors
Salas AP, Zhu L, Sanchez C, Brana AF, Rohr J, Mendez C, Salas JA
  Title
Deciphering the late steps in the biosynthesis of the anti-tumour indolocarbazole staurosporine: sugar donor substrate flexibility of the StaG glycosyltransferase.
  Journal
Mol Microbiol 58:17-27 (2005)
DOI:10.1111/j.1365-2958.2005.04777.x
  Sequence
[ag:BAC55218]
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