KEGG ORTHOLOGY: K20166

ORTHOLOGY: K20166

Entry

K20166                      KO

Symbol

TBC1D2B

Name

TBC1 domain family member 2B

Disease

H02459

Syndromic neurodevelopmental disorder

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K20166  TBC1D2B; TBC1 domain family member 2B
Membrane trafficking [BR:ko04131]
Protein recycling
  Rab GTPases and associated proteins
   Other Rab GTPase associated proteins
    K20166  TBC1D2B; TBC1 domain family member 2B

Other DBs

GO:	0005096 0017137

Genes

HSA:	23102(TBC1D2B)

PTR:	453563(TBC1D2B)

PPS:	100985865(TBC1D2B)

GGO:	101133749(TBC1D2B)

PON:	129056984(TBC1D2B)

PPYG:

129013986(TBC1D2B)

NLE:	100605159(TBC1D2B)

HMH:	116481520(TBC1D2B)

SSYN:

129482196(TBC1D2B)

MCC:	716076(TBC1D2B)

MCF:	102136901(TBC1D2B)

MTHB:

126960040

MNI:	105493153(TBC1D2B)

CSAB:

103245259(TBC1D2B)

CATY:

105572001(TBC1D2B)

PANU:

101026685(TBC1D2B)

TGE:	112627717(TBC1D2B)

MLEU:

105541597(TBC1D2B)

RRO:	104674379(TBC1D2B)

RBB:	108524294(TBC1D2B)

TFN:	117098332(TBC1D2B)

PTEH:

111529628(TBC1D2B)

CANG:

105509257(TBC1D2B)

CJC:	100388646(TBC1D2B)

SBQ:	101035978(TBC1D2B)

CIMI:

108296752(TBC1D2B)

ANAN:

105720924(TBC1D2B)

CSYR:

103258592(TBC1D2B)

MMUR:

105856548(TBC1D2B)

LCAT:

123644429(TBC1D2B)

PCOQ:

105822764(TBC1D2B)

OGA:	100946274(TBC1D2B)

MMU:	67016(Tbc1d2b)

MCAL:

110302407(Tbc1d2b)

MPAH:

110328409(Tbc1d2b)

RNO:	315880(Tbc1d2b)

MCOC:

116073585(Tbc1d2b)

ANU:	117693410(Tbc1d2b)

MUN:	110549488(Tbc1d2b)

CGE:	100756102(Tbc1d2b)

MAUA:

101827698(Tbc1d2b)

PROB:

127238648(Tbc1d2b)

PLEU:

114690946(Tbc1d2b)

MORG:

121464357(Tbc1d2b)

MFOT:

126510629

AAMP:

119809000(Tbc1d2b)

NGI:	103726018(Tbc1d2b)

HGL:	101709524(Tbc1d2b)

CPOC:

100729045(Tbc1d2b)

CCAN:

109686825(Tbc1d2b)

DORD:

105982379(Tbc1d2b)

DSP:	122123418(Tbc1d2b)

PLOP:

125368246(Tbc1d2b)

NCAR:

124975992

MMMA:

107137899(Tbc1d2b)

OCU:

100337848

OPI:	101533615(TBC1D2B)

TUP:	102481049(TBC1D2B)

GVR:	103601850(TBC1D2B)

CFA:	488776(TBC1D2B)

CLUD:

112653167(TBC1D2B)

VVP:	112922755(TBC1D2B)

VLG:	121488842(TBC1D2B)

NPO:	129510196(TBC1D2B)

AML:	100481764(TBC1D2B)

UMR:	103660303(TBC1D2B)

UAH:	113263575(TBC1D2B)

UAR:	123796877(TBC1D2B)

ELK:

111152684

LLV:

125103816

MPUF:

101671871(TBC1D2B)

MNP:	131998956(TBC1D2B)

MLK:	131835480(TBC1D2B)

NVS:	122893261(TBC1D2B)

ORO:	101369319(TBC1D2B)

EJU:	114201266(TBC1D2B)

ZCA:	113909928(TBC1D2B)

MLX:	118023172(TBC1D2B)

NSU:	110572217(TBC1D2B)

LWW:	102742057(TBC1D2B)

FCA:	101091943(TBC1D2B)

PYU:	121042258(TBC1D2B)

PCOO:

112855111(TBC1D2B)

PBG:	122468166(TBC1D2B)

PVIV:

125159011(TBC1D2B)

LRUF:

124527852

PTG:	102966553(TBC1D2B)

PPAD:

109273579(TBC1D2B)

PUC:

125910848

AJU:

106988471

HHV:	120248506(TBC1D2B)

BTA:	535927(TBC1D2B)

BOM:	102283245(TBC1D2B)

BIU:	109575494(TBC1D2B)

BBUB:

102391724(TBC1D2B)

BBIS:

104991040(TBC1D2B)

CHX:	102179986(TBC1D2B)

OAS:	101114393(TBC1D2B)

BTAX:

128066394(TBC1D2B)

ODA:	120875513(TBC1D2B)

CCAD:

122419732(TBC1D2B)

MBEZ:

129550396(TBC1D2B)

SSC:	100156840(TBC1D2B)

CFR:	102504028(TBC1D2B)

CBAI:

105069144(TBC1D2B)

CDK:	105092228(TBC1D2B)

VPC:	102540737(TBC1D2B)

BACU:

103019368(TBC1D2B)

BMUS:

118890556(TBC1D2B)

LVE:	103086610(TBC1D2B)

OOR:	101280199(TBC1D2B)

DLE:	111177881(TBC1D2B)

PCAD:

102977039(TBC1D2B)

PSIU:

116749679(TBC1D2B)

NASI:

112405776(TBC1D2B)

ECB:	100060015(TBC1D2B)

EPZ:	103559015(TBC1D2B)

EAI:	106840819(TBC1D2B)

MYB:	102247857(TBC1D2B)

MYD:

102753927

MMYO:

118679086(TBC1D2B)

MDT:	132222968(TBC1D2B)

PKL:	118719738(TBC1D2B)

EFUS:

103303836(TBC1D2B)

MNA:	107525551(TBC1D2B)

DRO:	112306148(TBC1D2B)

SHON:

118991860(TBC1D2B)

AJM:	119057235(TBC1D2B)

PDIC:

114488697(TBC1D2B)

PHAS:

123809694(TBC1D2B)

MMF:	118640920(TBC1D2B)

PPAM:

129083054(TBC1D2B)

HAI:	109381401(TBC1D2B)

RFQ:	117018806(TBC1D2B)

PALE:

102890121(TBC1D2B)

PGIG:

120599331(TBC1D2B)

PVP:	105301641(TBC1D2B)

RAY:	107500514(TBC1D2B)

MJV:	108397413(TBC1D2B)

TOD:	119244277(TBC1D2B)

SARA:

101550712(TBC1D2B)

SETR:

126022692(TBC1D2B)

LAV:	100661271(TBC1D2B)

TMU:

101360183

ETF:	101656560(TBC1D2B)

DNM:	101421861(TBC1D2B)

MDO:	100026249(TBC1D2B)

GAS:	123233007(TBC1D2B)

SHR:	111718706(TBC1D2B)

AFZ:

127552042

PCW:	110200608(TBC1D2B)

TVP:	118828789(TBC1D2B)

OAA:	100086039(TBC1D2B)

GGA:	415364(TBC1D2B)

PCOC:

116244599(TBC1D2B)

MGP:

100538487

CJO:	107318541(TBC1D2B)

TPAI:

128075123(TBC1D2B)

LMUT:

125698180(TBC1D2B)

NMEL:

110403982(TBC1D2B)

APLA:

101802887(TBC1D2B)

ACYG:

106033764(TBC1D2B)

CATA:

118251671(TBC1D2B)

AFUL:

116493497(TBC1D2B)

TGU:	100232735(TBC1D2B)

LSR:	110479823(TBC1D2B)

SCAN:

103823200(TBC1D2B)

PMOA:

120513237(TBC1D2B)

OTC:	121348312(TBC1D2B)

PRUF:

121365515(TBC1D2B)

GFR:	102031705(TBC1D2B)

FAB:	101810480(TBC1D2B)

OMA:	130257348(TBC1D2B)

PHI:	102102493(TBC1D2B)

PMAJ:

107209227(TBC1D2B)

CCAE:

111934225(TBC1D2B)

CCW:	104683790(TBC1D2B)

CBRC:

103618317(TBC1D2B)

ETL:	114066689(TBC1D2B)

ZAB:	102074655(TBC1D2B)

ZLE:	135452217(TBC1D2B)

ACHL:

103808603(TBC1D2B)

SVG:	106854945(TBC1D2B)

MMEA:

130575036(TBC1D2B)

HRT:	120758659(TBC1D2B)

SATI:

136367251(TBC1D2B)

FPG:	101923423(TBC1D2B)

FCH:	102056362(TBC1D2B)

CCRI:

104157476(TBC1D2B)

NNT:	104399310(TBC1D2B)

SHAB:

115613027(TBC1D2B)

ACUN:

113483883(TBC1D2B)

TALA:

104366478(TBC1D2B)

ACHC:

115341368(TBC1D2B)

HALD:

104316391(TBC1D2B)

HLE:	104834420(TBC1D2B)

AGEN:

126043664

GCL:

127020848

CSTI:

104555365(TBC1D2B)

LDI:	104340638(TBC1D2B)

MNB:	103769691(TBC1D2B)

DPUB:

104309971(TBC1D2B)

AVIT:

104277551(TBC1D2B)

BRHI:

104500446(TBC1D2B)

EGZ:	104130858(TBC1D2B)

NNI:	104016744(TBC1D2B)

PCRI:

104024499(TBC1D2B)

PCAO:

104039556(TBC1D2B)

PADL:

103921996(TBC1D2B)

AFOR:

103894581(TBC1D2B)

FGA:	104069448(TBC1D2B)

GSTE:

104250561(TBC1D2B)

CLV:	102095864(TBC1D2B)

MUI:	104539873(TBC1D2B)

PGUU:

104457636(TBC1D2B)

PLET:

104626501(TBC1D2B)

EHS:	104502936(TBC1D2B)

CMAC:

104473277(TBC1D2B)

CUCA:

104056891(TBC1D2B)

TEO:	104379029(TBC1D2B)

BREG:

104634800(TBC1D2B)

OHA:	104337407(TBC1D2B)

ACAR:

104532804(TBC1D2B)

CPEA:

104385977(TBC1D2B)

CVF:	104287950(TBC1D2B)

RTD:	128914458(TBC1D2B)

AAM:	106496581(TBC1D2B)

AROW:

112971922(TBC1D2B)

NPD:	112946706(TBC1D2B)

TGT:	104573373(TBC1D2B)

DNE:	112989215(TBC1D2B)

SCAM:

104148350(TBC1D2B)

ASN:	102383624(TBC1D2B)

AMJ:	102557869(TBC1D2B)

CPOO:

109308918(TBC1D2B)

GGN:	109288701(TBC1D2B)

PSS:	102451641(TBC1D2B)

CMY:	102946040(TBC1D2B)

CCAY:

125643893(TBC1D2B)

DCC:	119862525(TBC1D2B)

CPIC:

101948308(TBC1D2B)

TST:	117883584(TBC1D2B)

CABI:

116815049(TBC1D2B)

MRV:	120373527(TBC1D2B)

ACS:	100554839(tbc1d2b)

ASAO:

132762572(TBC1D2B)

PVT:	110074518(TBC1D2B)

SUND:

121932591(TBC1D2B)

PBI:	103059732(TBC1D2B)

PMUR:

107283172(TBC1D2B)

CTIG:

120306560(TBC1D2B)

TSR:	106542878(TBC1D2B)

PGUT:

117660948(TBC1D2B)

APRI:

131184513(TBC1D2B)

PTEX:

113442197(TBC1D2B)

NSS:	113421576(TBC1D2B)

VKO:	123027690(TBC1D2B)

PMUA:

114584734(TBC1D2B)

PRAF:

128401383(TBC1D2B)

ZVI:	118092619(TBC1D2B)

HCG:	128334963(TBC1D2B)

GJA:	107117949(TBC1D2B)

STOW:

125424458(TBC1D2B)

EMC:	129345221(TBC1D2B)

XLA:	108711285(tbc1d2b.L) 108713000(tbc1d2b.S)

XTR:	734055(tbc1d2b)

NPR:	108784033(TBC1D2B)

RTEM:

120931534(TBC1D2B)

BBUF:

120985611(TBC1D2B)

BGAR:

122929712(TBC1D2B)

MUO:	115458273(TBC1D2B)

GSH:	117348276(TBC1D2B)

DRE:	100330777(tbc1d2b)

SRX:	107752318 107757764

SANH:

107659498 107698183

SGH:	107573341(tbc1d2b) 107598894

CCAR:

109051111 109104733

CAUA:

113043404 113066995

CGIB:

127947282 128014162

PTET:

122331013(tbc1d2b)

LROH:

127156694(tbc1d2b)

OMC:	131534550(tbc1d2b)

PPRM:

120460278(tbc1d2b)

RKG:	130099308(tbc1d2b)

MAMB:

125247365(tbc1d2b)

CIDE:

127507204

CERY:

137015251(tbc1d2b)

MASI:

127435804 127437489

TROS:

130551510(tbc1d2b)

TDW:	130414313(tbc1d2b)

MANU:

129433739(tbc1d2b)

IPU:

108275120

IFU:	128617848(tbc1d2b)

PHYP:

113529827(tbc1d2b)

SMEO:

124392672(tbc1d2b)

TFD:	113660049(tbc1d2b)

TVC:	132856688(tbc1d2b)

TRN:	134310242(tbc1d2b)

AMEX:

103026709(tbc1d2b)

CMAO:

118811674(tbc1d2b)

EEE:	113573146(tbc1d2b)

CHAR:

105892396(tbc1d2b)

TRU:	101068753(tbc1d2b)

TFS:	130536125(tbc1d2b)

TNG:	GSTEN00015989G001

LCO:	104931407(tbc1d2b)

NCC:	104953444(tbc1d2b)

TBEN:

117491211(tbc1d2b)

CGOB:

115009515(tbc1d2b)

PGEO:

117448245(tbc1d2b)

GACU:

117538877(tbc1d2b)

EMAC:

134876548(tbc1d2b)

ELY:	117261857(tbc1d2b)

EFO:	125886960(tbc1d2b)

PLEP:

121950513(tbc1d2b)

SLUC:

116038389(tbc1d2b)

ECRA:

117948859(tbc1d2b)

ESP:	116693981(tbc1d2b)

PFLV:

114559826(tbc1d2b)

GAT:	120809016(tbc1d2b) 120812639

PPUG:

119195774(tbc1d2b)

AFB:	129107682(tbc1d2b)

CLUM:

117731884(tbc1d2b)

PSWI:

130194870(tbc1d2b)

MSAM:

119893730(tbc1d2b)

SCHU:

122874855(tbc1d2b)

CUD:	121515127(tbc1d2b)

ALAT:

119024153(tbc1d2b)

MZE:	101475660(tbc1d2b)

ONL:	100701981(tbc1d2b)

OAU:	116326246(tbc1d2b)

OLA:	101174263(tbc1d2b)

OML:	112152536(tbc1d2b)

CSAI:

133444216(tbc1d2b)

XMA:	102223451(tbc1d2b)

XCO:	114156580(tbc1d2b)

XHE:	116732505(tbc1d2b)

PRET:

103466572(tbc1d2b)

PFOR:

103141237(tbc1d2b)

PLAI:

106956568(tbc1d2b)

PMEI:

106926799(tbc1d2b)

GAF:	122835055(tbc1d2b)

PPRL:

129365475(tbc1d2b)

CVG:	107099233(tbc1d2b)

CTUL:

119772424(tbc1d2b)

GMU:	124858003(tbc1d2b)

NFU:	107388749(tbc1d2b)

KMR:	108229841(tbc1d2b)

ALIM:

106514381(tbc1d2b)

NWH:	119416445(tbc1d2b)

AOCE:

111581265(tbc1d2b)

MCEP:

125014533(tbc1d2b)

CSEM:

103379968(tbc1d2b)

POV:	109624561(tbc1d2b)

SSEN:

122775667(tbc1d2b)

HHIP:

117763064(tbc1d2b)

HSP:	118109236(tbc1d2b)

PPLT:

128445155(tbc1d2b)

SMAU:

118315616(tbc1d2b)

LCF:

108886154

SDU:	111228369(tbc1d2b)

SLAL:

111667051(tbc1d2b)

XGL:	120793279(tbc1d2b)

HCQ:	109519414(tbc1d2b)

SSCV:

125970726

SBIA:

133502215(tbc1d2b)

PEE:	133402333(tbc1d2b)

PTAO:

133478426(tbc1d2b)

BPEC:

110167666(tbc1d2b)

MALB:

109971276(tbc1d2b)

BSPL:

114857256(tbc1d2b)

SJO:	128358708(tbc1d2b)

STRU:

115192996(tbc1d2b)

OTW:	112255884 121838805

OMY:	110521130(tbc1d2b)

OGO:	124037425(tbc1d2b)

OKI:	109898135(tbc1d2b)

OKE:	118381652(tbc1d2b)

CCLU:

121555629(tbc1d2b)

ELS:	105008125(tbc1d2b)

SFM:	108941244(tbc1d2b)

PKI:	111846905(tbc1d2b)

AANG:

118215388(tbc1d2b) 118228101

LOC:	102684514(tbc1d2b)

PSPA:

121294699 121299011

ARUT:

117427877 117429151

PSEX:

120541746(tbc1d2b)

LCM:	102346948(TBC1D2B)

CMK:	103188066(tbc1d2b)

CPLA:

122542447(tbc1d2b)

HOC:	132834683(tbc1d2b)

LERI:

129713569(tbc1d2b)

PMRN:

116941937 116954056

LRJ:	133343809(TBC1D2B) 133346441

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

ARUN:

SKO:

ZNE:

CSEC:

PVM:

PJA:

PCHN:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:

LSM:

TCF:

DSV:

RSAN:

RMP:

TUT:	107370875 107371254

DPTE:

DFR:

CSCU:

CVS:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

CEL:	CELE_ZK1248.10(tbc-2)

CBR:

CBG_02508

CRQ:	GCK72_006127

NAI:	NECAME_14395

BMY:	BM_BM7645(Bma-tbc-2)

LOA:	LOAG_16856

TSP:

Tsp_08861

HRO:	HELRODRAFT_88787

LGI:	LOTGIDRAFT_120741

PVUL:

PCAN:

GAE:

HRF:

HRJ:

CRG:

CANU:

CVN:	111121720 111122062

OED:

MYI:

PMAX:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

NVE:	5505456 5507434

EPA:	110234411 110248849

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_51695

AQU:	100631390 105316769

MBR:	MONBRDRAFT_33605

SRE:	PTSG_09213

PTM:	GSPATT00022735001

» show all

Reference

PMID:22354992

Authors

Popovic D, Akutsu M, Novak I, Harper JW, Behrends C, Dikic I

Title

Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers.

Journal

Mol Cell Biol 32:1733-44 (2012)
DOI:10.1128/MCB.06717-11

Sequence

[hsa:23102]

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