| Entry |
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| Symbol |
oxyR, ctcR
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| Name |
5a,11a-dehydrotetracycline reductase [EC: 1.3.98.4]
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| Pathway |
| map01057 | Biosynthesis of type II polyketide products |
| map01110 | Biosynthesis of secondary metabolites |
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| Module |
| M00780 | Tetracycline/oxytetracycline biosynthesis, pretetramide => tetracycline/oxytetracycline |
| M00823 | Chlortetracycline biosynthesis, pretetramide => chlortetracycline |
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| Reaction |
| R05459 | tetracycline:coenzyme-F420 oxidoreductase |
| R09192 | oxytetracycline:coenzyme-F420 oxidoreductase |
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| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01057 Biosynthesis of type II polyketide products
K21301 oxyR, ctcR; 5a,11a-dehydrotetracycline reductase
00253 Tetracycline biosynthesis
K21301 oxyR, ctcR; 5a,11a-dehydrotetracycline reductase
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins
K21301 oxyR, ctcR; 5a,11a-dehydrotetracycline reductase
Enzymes [BR:ko01000]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.98 With other, known, physiological acceptors
1.3.98.4 5a,11a-dehydrotetracycline reductase
K21301 oxyR, ctcR; 5a,11a-dehydrotetracycline reductase
Polyketide biosynthesis proteins [BR:ko01008]
Polyketide tailoring proteins
Others
K21301 oxyR, ctcR; 5a,11a-dehydrotetracycline reductase
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| Genes |
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| Reference |
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| Authors |
Zhang W, Ames BD, Tsai SC, Tang Y |
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| Title |
Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Wang P, Bashiri G, Gao X, Sawaya MR, Tang Y |
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| Title |
Uncovering the enzymes that catalyze the final steps in oxytetracycline biosynthesis. |
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| Journal |
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| LinkDB |
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