KEGG   ORTHOLOGY: K21692
Entry
K21692                      KO                                     
Symbol
CYP82N4
Name
methyltetrahydroprotoberberine 14-monooxygenase [EC:1.14.14.97]
Pathway
map00950  Isoquinoline alkaloid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00945  Sanguinarine biosynthesis, (S)-reticuline => sanguinarine
Reaction
R03842  (S)-cis-N-methylcanadine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (14-hydroxylating)
R04700  (S)-cis-N-methylstylopine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (14-hydroxylating)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00950 Isoquinoline alkaloid biosynthesis
    K21692  CYP82N4; methyltetrahydroprotoberberine 14-monooxygenase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K21692  CYP82N4; methyltetrahydroprotoberberine 14-monooxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.97  methyltetrahydroprotoberberine 14-monooxygenase
     K21692  CYP82N4; methyltetrahydroprotoberberine 14-monooxygenase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, plant type
  CYP82 family
   K21692  CYP82N4; methyltetrahydroprotoberberine 14-monooxygenase
Other DBs
GO: 0047084
Genes
PSOM: 113322770
AG: AGC92398(CYP82N4)
Reference
PMID:23313486
  Authors
Beaudoin GA, Facchini PJ
  Title
Isolation and characterization of a cDNA encoding (S)-cis-N-methylstylopine 14-hydroxylase from opium poppy, a key enzyme in sanguinarine biosynthesis.
  Journal
Biochem Biophys Res Commun 431:597-603 (2013)
DOI:10.1016/j.bbrc.2012.12.129
  Sequence
[ag:AGC92398]
LinkDB

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