KEGG   ORTHOLOGY: K22472
Entry
K22472            Tight     KO                                     

Name
NS5B
Definition
HCV RNA-dependent RNA polymerase
Pathway
ko05160  Hepatitis C
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    K22472  NS5B; HCV RNA-dependent RNA polymerase
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03200 Viral proteins
    K22472  NS5B; HCV RNA-dependent RNA polymerase
Viral proteins [BR:ko03200]
 +ssRNA viruses
  Hepatitis C virus
   K22472  NS5B; HCV RNA-dependent RNA polymerase
Genes
AG: NP_751928(NS5B)
Reference
  Authors
Marascio N, Torti C, Liberto M, Foca A
  Title
Update on different aspects of HCV variability: focus on NS5B polymerase.
  Journal
BMC Infect Dis 14 Suppl 5:S1 (2014)
DOI:10.1186/1471-2334-14-S5-S1
  Sequence
Reference
  Authors
Scheel TK, Rice CM
  Title
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies.
  Journal
Nat Med 19:837-49 (2013)
DOI:10.1038/nm.3248
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