KEGG ORTHOLOGY: K22937

ORTHOLOGY: K22937

Entry

K22937                      KO

Symbol

LYST, CHS1

Name

lysosomal-trafficking regulator

Disease

H02021

Chediak-Higashi syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K22937  LYST, CHS1; lysosomal-trafficking regulator
Membrane trafficking [BR:ko04131]
Endosome - Lysosome transport
  Others
   Others
    K22937  LYST, CHS1; lysosomal-trafficking regulator

Genes

HSA:	1130(LYST)

PTR:	457838(LYST)

PPS:	100981133(LYST)

GGO:	101142325(LYST)

PON:	100441491(LYST)

NLE:	100597105(LYST)

HMH:	116457215(LYST)

MCC:	718051(LYST)

MCF:	102143435(LYST)

MTHB:

126942616

MNI:	105474609(LYST)

CSAB:

103230802(LYST)

CATY:

105574893(LYST)

PANU:

101021324(LYST)

TGE:	112634929(LYST)

MLEU:

105546879

RRO:	104679176(LYST)

RBB:	108522221(LYST)

TFN:	117075556(LYST)

PTEH:

111545243(LYST)

CANG:

105507300(LYST)

CJC:	100410662(LYST)

SBQ:	101045715(LYST)

CIMI:

108302841(LYST)

CSYR:

103255669(LYST)

MMUR:

105856486(LYST)

LCAT:

123627586(LYST)

PCOQ:

105823076(LYST)

OGA:	100940433(LYST)

MMU:	17101(Lyst)

MCAL:

110307810(Lyst)

MPAH:

110333788(Lyst)

RNO:	85419(Lyst)

MCOC:

116082523(Lyst)

ANU:	117713627(Lyst)

MUN:	110558138(Lyst)

CGE:	100768280(Lyst)

MAUA:

101842610(Lyst)

PROB:

127229770(Lyst)

PLEU:

114685175(Lyst)

MORG:

121432724(Lyst)

MFOT:

126501663

AAMP:

119817961(Lyst)

NGI:	103745128(Lyst)

HGL:	101707129(Lyst)

CPOC:

100730206(Lyst)

CCAN:

109692617(Lyst)

DORD:

105984383(Lyst)

DSP:	122113059(Lyst)

PLOP:

125367326(Lyst)

NCAR:

124961500

MMMA:

107157926(Lyst)

OCU:	100339012 103351034

OPI:	101531487(LYST)

TUP:	102476987(LYST)

GVR:	103602784(LYST)

CFA:	479195(LYST)

CLUD:

112660910(LYST)

VVP:	112927369(LYST)

VLG:	121486691(LYST)

NPO:	129499091(LYST)

AML:	100468700(LYST)

UMR:	103661900(LYST)

UAH:	113259277(LYST)

UAR:	123783046(LYST)

ELK:

111160518

LLV:

125085143

MPUF:

101688558(LYST)

MNP:	132016145(LYST)

MLK:	131829050(LYST)

NVS:	122900571(LYST)

ORO:	101369082(LYST)

EJU:	114210357(LYST)

ZCA:	113918796(LYST)

MLX:	118012934(LYST)

NSU:	110586064(LYST)

LWW:	102748111(LYST)

FCA:	101081414(LYST)

PYU:	121023146(LYST)

PCOO:

112851575(LYST)

PBG:	122492708(LYST)

PVIV:

125148321(LYST)

LRUF:

124518689

PTG:	102954281(LYST)

PPAD:

109248873(LYST)

PUC:

125932578

AJU:

106982551

HHV:	120241807(LYST)

BTA:	281072(LYST)

BOM:	102279397(LYST)

BIU:	109553758(LYST)

BBUB:

102406137(LYST)

BBIS:

105003124(LYST)

CHX:	102170942(LYST)

OAS:	101115340(LYST)

BTAX:

128048031(LYST)

ODA:	120860491 120865417

CCAD:

122446611(LYST)

MBEZ:

129555855(LYST)

SSC:	100049676(LYST)

CFR:	102510593(LYST)

CBAI:

105075112(LYST)

CDK:	105088844(LYST)

VPC:	102526760(LYST)

BACU:

103019897(LYST)

BMUS:

118882545(LYST)

LVE:	103082398(LYST)

OOR:	101271512(LYST)

DLE:	111163934(LYST)

PCAD:

102976128(LYST)

PSIU:

116741616(LYST)

NASI:

112410740(LYST)

ECB:	100050724(LYST)

EPZ:	103547678(LYST)

EAI:	106834698(LYST)

MYB:	102240076(LYST)

MYD:	102763491(LYST)

MMYO:

118678722(LYST)

MLF:	102422439 102430474

PKL:	118727680(LYST)

EFUS:

103293438(LYST)

MNA:	107527187(LYST)

DRO:	112305878(LYST)

SHON:

118980660(LYST)

AJM:	119044228 119065951(LYST)

PDIC:

114512237(LYST)

PHAS:

123804638(LYST)

MMF:	118640509(LYST)

PPAM:

129072100(LYST)

HAI:	109387716(LYST)

RFQ:	117018661(LYST)

PALE:

102897476(LYST)

PGIG:

120592625(LYST)

PVP:	105302727(LYST)

RAY:	107520047(LYST)

MJV:	108399461(LYST)

TOD:	119244583(LYST)

SARA:

101544214(LYST)

SETR:

126030797(LYST)

LAV:	100664464(LYST)

TMU:

101357280

ETF:	101661440(LYST)

DNM:	101442148(LYST)

MDO:	100619622(LYST)

GAS:	123245616(LYST)

SHR:	100921256(LYST)

AFZ:

127559634

PCW:	110217881(LYST)

OAA:	100081827(LYST)

GGA:	421514(LYST)

PCOC:

116228355(LYST)

MGP:	100550123(LYST)

CJO:	107311369(LYST)

TPAI:

128075204(LYST)

LMUT:

125690200(LYST)

NMEL:

110396438(LYST)

APLA:

101802189(LYST)

ACYG:

106048818(LYST)

CATA:

118254120(LYST)

AFUL:

116487008(LYST)

TGU:	100230901(LYST)

LSR:	110468866(LYST)

SCAN:

103818522(LYST)

PMOA:

120501263(LYST)

OTC:	121341031(LYST)

PRUF:

121363298(LYST)

GFR:	102040322(LYST)

FAB:	101812819(LYST)

OMA:	130251519(LYST)

PHI:	102112723(LYST)

PMAJ:

107201945(LYST)

CCAE:

111926851(LYST)

CCW:	104684285(LYST)

CBRC:

103624081(LYST)

ETL:	114066546(LYST)

ZAB:	102066601(LYST)

ACHL:

103800345(LYST)

SVG:	106852240(LYST)

MMEA:

130588788(LYST)

HRT:	120750117(LYST)

FPG:	101910820(LYST)

FCH:	102046356(LYST)

CLV:	102094920(LYST)

EGZ:	104131014(LYST)

NNI:	104019869(LYST)

PCRI:

104038297(LYST)

PLET:

104627529(LYST)

EHS:

104514676

PCAO:

104052799(LYST)

ACUN:

113478535(LYST)

TALA:

104359026(LYST)

PADL:

103921231(LYST)

AFOR:

103900992(LYST)

ACHC:

115349959(LYST)

HALD:

104314480(LYST)

HLE:	104828733(LYST)

AGEN:

126051822

GCL:

127014160

CCRI:

104163758(LYST)

CSTI:

104550600

CMAC:

104480416(LYST)

BREG:

104640358(LYST)

FGA:	104078968(LYST)

GSTE:

104256279(LYST)

LDI:	104354147(LYST)

MNB:	103770623(LYST)

OHA:	104328290(LYST)

NNT:	104413522(LYST)

SHAB:

115614032(LYST)

DPUB:

104305228(LYST)

PGUU:

104458637(LYST)

ACAR:

104528482(LYST)

CPEA:

104388690(LYST)

AVIT:

104271219

CVF:	104287252(LYST)

RTD:	128907154(LYST)

CUCA:

104060349(LYST)

TEO:	104380744(LYST)

BRHI:

104491554(LYST)

AAM:	106486815(LYST)

AROW:

112964539(LYST)

NPD:	112951933(LYST)

TGT:	104573818(LYST)

DNE:	112988997(LYST)

SCAM:

104148174(LYST)

ASN:	102374372(LYST)

AMJ:	102561444(LYST)

CPOO:

109319966(LYST)

GGN:	109304512(LYST)

PSS:	102460343(LYST)

CMY:	102935852(LYST)

CCAY:

125633873(LYST)

DCC:	119852820(LYST)

CPIC:

101932873(LYST)

TST:	117875482(LYST)

CABI:

116821682(LYST)

MRV:	120400421(LYST)

ACS:	100557273(lyst)

ASAO:

132761202(LYST)

PVT:	110075654(LYST)

SUND:

121931456(LYST)

PBI:	103052064(LYST) 103057306 103058668

PMUR:

107288314(LYST)

CTIG:

120312348(LYST)

TSR:

106538195

PGUT:

117671969(LYST)

APRI:

131189723(LYST)

PTEX:

113439372(LYST)

NSS:	113413291(LYST)

VKO:	123018156(LYST)

PMUA:

114594414(LYST)

PRAF:

128410832(LYST)

ZVI:	118081863(LYST)

HCG:	128346499(LYST)

GJA:	107117654(LYST)

STOW:

125426913(LYST)

EMC:	129326772(LYST)

XLA:

101027285

XTR:	779601(lyst)

NPR:	108788001(LYST)

RTEM:

120937424(LYST)

BBUF:

120998673(LYST)

BGAR:

122935042(LYST)

MUO:	115465435(LYST)

GSH:	117356744(LYST)

DRE:	100150726(lyst)

SRX:	107728318 107730379

SANH:

107689764 107691204

SGH:	107557718(lyst) 107569426

CCAR:

109102661 109112143 109112148

CAUA:

113056630(lyst) 113112320

CGIB:

127970404 128025860

PTET:

122356212(lyst)

LROH:

127175506(lyst)

OMC:	131551775(lyst)

PPRM:

120461177(lyst)

RKG:	130068996(lyst)

MAMB:

125276474(lyst)

CIDE:

127525477

MASI:

127411909 127414352

TROS:

130559636(lyst)

TDW:	130431346(lyst)

MANU:

129415472(lyst)

IPU:

108261076

IFU:	128605356(lyst)

PHYP:

113542007(lyst)

SMEO:

124396944(lyst)

TFD:	113644978(lyst)

TVC:	132847062(lyst)

AMEX:

103033034(lyst)

CMAO:

118810724(lyst)

EEE:	113577749(lyst)

CHAR:

105902255(lyst)

TRU:	101062501(lyst)

TFS:	130533369(lyst)

TNG:	GSTEN00030876G001

LCO:	104934546(lyst)

NCC:	104960297(lyst)

TBEN:

117499969(lyst)

CGOB:

115019746(lyst)

PGEO:

117459654(lyst)

GACU:

117553412(lyst)

EMAC:

134858823(lyst)

ELY:	117248040(lyst)

EFO:	125903361(lyst)

PLEP:

121954974(lyst)

SLUC:

116051130(lyst)

ECRA:

117960108(lyst)

ESP:	116705713(lyst)

PFLV:

114571715(lyst)

GAT:	120820343(lyst)

PPUG:

119213958(lyst)

AFB:	129091992(lyst)

CLUM:

117744409(lyst)

PSWI:

130207632(lyst)

MSAM:

119916997(lyst)

SCHU:

122884522(lyst)

CUD:	121511586(lyst)

ALAT:

119033414(lyst)

MZE:	101476748(lyst)

ONL:	100694037(lyst)

OAU:	116318521(lyst)

OLA:	101170120(lyst)

OML:	112161466(lyst)

CSAI:

133463998(lyst)

XMA:	102234327(lyst)

XCO:	114137452(lyst)

XHE:	116713156(lyst)

PRET:

103477259(lyst)

PFOR:

103137661(lyst)

PLAI:

106949760(lyst)

PMEI:

106923826

GAF:	122842455(lyst)

PPRL:

129359630(lyst)

CVG:	107087804(lyst)

CTUL:

119782863(lyst)

GMU:	124859561(lyst)

NFU:	107375428(lyst)

KMR:	108240656(lyst)

ALIM:

106515873(lyst)

NWH:	119411192(lyst)

AOCE:

111573714(lyst)

MCEP:

125018968(lysT)

CSEM:

103387614(lyst)

POV:	109630601(lyst) 109647567

SSEN:

122773164

HHIP:

117775180(lyst)

HSP:	118118699(lyst)

SMAU:

118283514(lyst)

LCF:

108885796

SDU:	111220560(lyst)

SLAL:

111658939(lyst)

XGL:	120796310(lyst)

HCQ:	109516216(lyst)

SSCV:

125978079

SBIA:

133509752(lyst)

PEE:	133410216(lyst)

PTAO:

133485568(lyst)

BPEC:

110156774(lyst)

MALB:

109960817(lyst)

BSPL:

114870625(lyst)

SJO:	128372611(lyst)

SASA:

106578744 106591199

STRU:

115155327(lyst)

OTW:	112236521 112237442

OMY:	110492789(lyst)

OGO:	124048031(lyst)

OKI:	109866052(lyst)

OKE:	118381102(lyst)

SALP:

112074671

CCLU:

121574315(lyst)

ELS:	105006092(lyst)

SFM:	108927089 108933602(lyst)

PKI:	111835683 111856370(lyst)

AANG:

118217551 118220324

LOC:	102696080(lyst)

PSPA:

121316074 121317201(lyst)

ARUT:

117402875 117411061

PSEX:

120516289(lyst)

LCM:	102355328(LYST)

CMK:	103178879(lyst)

RTP:	109922054(lyst)

CPLA:

122542341(lyst)

HOC:	132833965(lyst)

LERI:

129696992(lyst)

PMRN:

116939665(LYST)

LRJ:	133347320(LYST)

BFO:

BBEL:

CIN:

SCLV:

SPU:

APLC:

SKO:

DME:	Dmel_CG42863(mv)

DER:

6545963

DSE:

6610432

DSI:	Dsimw501_GD13422(Dsim_GD13422)

DYA:	Dyak_GE20897

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI12178

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

AOQ:

TDA:

MDE:	101889306 131806483

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AAG:

AALB:

CQU:	CpipJ_CPIJ005368

CPII:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CCIN:

BMOR:

BMAN:

MSEX:

DPL:	KGM_209457

PMAC:

PXU:

PRAP:

ZCE:

AAGE:

HAW:	110376889(Mv)

HZE:

TNL:

SLIU:

OFU:

PXY:

CCRN:

API:

DNX:

AGS:

RMD:

BTAB:

CLEC:

HHAL:

NLU:

PHU:	Phum_PHUM351440

FOC:

TPAL:

ZNE:

CSEC:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_195317 DAPPUDRAFT_316324

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

PCLA:

PTRU:

HAZT:

EAF:

LSM:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

ABRU:

SDM:

LOA:	LOAG_16516

TSP:	Tsp_07712 Tsp_12811

HRO:	HELRODRAFT_191731

LGI:	LOTGIDRAFT_161637

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:

MYI:

PMAX:

MMER:

OBI:

OSN:

LAK:

SMM:	Smp_162930

EGL:

EGR_03651

NVE:	5507137 5518881

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

TAD:	TRIADDRAFT_26285

AQU:

100641459

DDI:	DDB_G0271504(lvsB)

DPP:	DICPUDRAFT_159064

DFA:	DFA_10070(lvsB)

ACAN:

ACA1_365070

» show all

Reference

PMID:8896560

Authors

Nagle DL, Karim MA, Woolf EA, Holmgren L, Bork P, Misumi DJ, McGrail SH, Dussault BJ Jr, Perou CM, Boissy RE, Duyk GM, Spritz RA, Moore KJ

Title

Identification and mutation analysis of the complete gene for Chediak-Higashi syndrome.

Journal

Nat Genet 14:307-11 (1996)
DOI:10.1038/ng1196-307

Sequence

[hsa:1130]

LinkDB

DBGET integrated database retrieval system