KEGG   ORTHOLOGY: K22944
Entry
K22944                      KO                                     
Symbol
cyaA
Name
bifunctional hemolysin/adenylate cyclase [EC:4.6.1.1]
Pathway
map00230  Purine metabolism
map05133  Pertussis
Module
M00575  Pertussis pathogenicity signature, T1SS
Reaction
R00089  ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K22944  cyaA; bifunctional hemolysin/adenylate cyclase
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05133 Pertussis
    K22944  cyaA; bifunctional hemolysin/adenylate cyclase
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02042 Bacterial toxins
    K22944  cyaA; bifunctional hemolysin/adenylate cyclase
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K22944  cyaA; bifunctional hemolysin/adenylate cyclase
Bacterial toxins [BR:ko02042]
 Type III toxins: Intracellular toxins
  Adenylate cyclase
   Adenylate cyclase toxin (ACT)
    K22944  cyaA; bifunctional hemolysin/adenylate cyclase
Other DBs
COG: COG2931
GO: 0008294
Genes
BPE: BP0760(cyaA)
BPC: BPTD_0761(cyaA)
BPER: BN118_0468(cyaA)
BPET: B1917_3063(cyaA)
BPEU: Q425_33450(cyaA)
BPAR: BN117_0318(cyaA)
BPA: BPP0321(cyaA)
BBR: BB0324(cyaA)
BBM: BN115_0310(cyaA)
BBX: BBS798_0319(cyaA)
Reference
PMID:2905265
  Authors
Glaser P, Sakamoto H, Bellalou J, Ullmann A, Danchin A
  Title
Secretion of cyclolysin, the calmodulin-sensitive adenylate cyclase-haemolysin bifunctional protein of Bordetella pertussis.
  Journal
EMBO J 7:3997-4004 (1988)
DOI:10.1002/j.1460-2075.1988.tb03288.x
  Sequence
[bpe:BP0760]
LinkDB

DBGET integrated database retrieval system