KEGG ORTHOLOGY: K23616

ORTHOLOGY: K23616

Entry

K23616 KO

Name

ATXN1_1L

Definition

ataxin 1/1L

Pathway

ko04330

Notch signaling pathway

ko05017

Spinocerebellar ataxia

ko05022

Pathways of neurodegeneration - multiple diseases

Disease

H00063

Spinocerebellar ataxia (SCA)

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    K23616  ATXN1_1L; ataxin 1/1L
09160 Human Diseases
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    K23616  ATXN1_1L; ataxin 1/1L
   05022 Pathways of neurodegeneration - multiple diseases
    K23616  ATXN1_1L; ataxin 1/1L

Genes

HSA:	342371(ATXN1L) 6310(ATXN1)

PTR:	454229(ATXN1L) 747421(ATXN1)

PPS:	100990310(ATXN1) 100993086(ATXN1L)

GGO:	101124588(ATXN1) 101147933(ATXN1L)

PON:	100437511(ATXN1) 100445264(ATXN1L)

NLE:	100582146(ATXN1L) 100588152(ATXN1)

MCC:	702975(ATXN1) 709805(ATXN1L)

MCF:	102122648(ATXN1) 102140641(ATXN1L)

CSAB:

103222118(ATXN1) 103233181(ATXN1L)

RRO:	104654765(ATXN1L) 104672575(ATXN1) 115893600

RBB:	108514577 108529163(ATXN1L) 108538793(ATXN1)

CJC:	100402564(ATXN1) 100408610(ATXN1L)

SBQ:	101031424(ATXN1L) 101038016(ATXN1)

MMU:	20238(Atxn1) 52335(Atxn1l)

MCAL:

110299557(Atxn1l) 110307792(Atxn1)

MPAH:

110333744(Atxn1)

RNO:	103694328 25049(Atxn1)

MUN:	110556604(Atxn1) 110561599 110561600

CGE:	100755753(Atxn1l) 107978826(Atxn1)

NGI:	103735621(Atxn1l) 103745156(Atxn1)

HGL:	101701688(Atxn1l) 101710194(Atxn1)

CCAN:

109694285(Atxn1l) 109698519(Atxn1)

OCU:	100342336(ATXN1) 100353839(ATXN1L)

TUP:	102478854(ATXN1) 102496277(ATXN1L)

CFA:	488232(ATXN1) 489725(ATXN1L)

VVP:	112920526(ATXN1) 112929488(ATXN1L)

AML:	100467930(ATXN1) 100484944(ATXN1L)

UMR:	103665122(ATXN1) 103673594(ATXN1L)

UAH:	113252452(ATXN1L) 113264490(ATXN1)

ORO:	101363466(ATXN1L) 101373734(ATXN1)

ELK:	111152753 111156718

FCA:	101092268(ATXN1) 101101276(ATXN1L)

PTG:	102951445(ATXN1L)

PPAD:

109249600(ATXN1) 109270671(ATXN1L)

AJU:	106974177(ATXN1) 106988314(ATXN1L)

BTA:	521025(ATXN1L) 616399(ATXN1)

BOM:	102269167(ATXN1) 102277488(ATXN1L)

BIU:	109572480(ATXN1L) 109576749(ATXN1)

BBUB:

102401399(ATXN1) 102405289(ATXN1L)

CHX:	102179228(ATXN1L) 102184391(ATXN1)

OAS:	101103748(ATXN1L) 101113284(ATXN1)

SSC:	100514525(ATXN1L) 100623695(ATXN1)

CFR:	102516284(ATXN1L) 106730479(ATXN1)

CDK:	105088473(ATXN1L) 105089106(ATXN1)

BACU:

103019478(ATXN1)

LVE:	103072225(ATXN1) 103090240(ATXN1L)

OOR:	101274433(ATXN1L) 101285008(ATXN1)

DLE:	111179556(ATXN1L) 111181386(ATXN1)

PCAD:

102977280(ATXN1L) 102990777(ATXN1)

ECB:	100054435(ATXN1L) 111769168(ATXN1)

EPZ:	103549741(ATXN1) 103551735(ATXN1L)

EAI:	106830899(ATXN1L) 106847199(ATXN1)

MYB:	102254421(ATXN1) 102257051(ATXN1L)

MYD:	102761738(ATXN1L) 102765602(ATXN1)

MNA:	107524216(ATXN1L) 107531261(ATXN1)

HAI:	109389060(ATXN1L) 109395026(ATXN1)

DRO:	112300774(ATXN1L) 112309367(ATXN1)

PALE:

102886316(ATXN1L) 102891517(ATXN1)

RAY:	107497673(ATXN1) 107520546(ATXN1L)

MJV:	108392328(ATXN1) 108394514(ATXN1L)

LAV:	100665714(ATXN1L) 100667899(ATXN1)

TMU:	101358683 101359148

MDO:	100025666(ATXN1)

SHR:	100924878(ATXN1L) 105749349(ATXN1)

PCW:	110192516(ATXN1L) 110208692(ATXN1)

OAA:	100076905(ATXN1L) 103170056(ATXN1)

GGA:	420843(ATXN1) 427566(ATXN1L)

MGP:	100550025(ATXN1) 100550200(ATXN1L)

CJO:	107309679(ATXN1) 107319453(ATXN1L)

NMEL:

110394164(ATXN1) 110404153(ATXN1L)

APLA:

101794164(ATXN1L) 101803445(ATXN1)

ACYG:

106041700(ATXN1) 106046622(ATXN1L)

TGU:	100219911(ATXN1L) 100230847(ATXN1)

LSR:	110468810(ATXN1L) 110483270(ATXN1)

SCAN:

103812735(ATXN1) 103816917(ATXN1L)

GFR:	102035223(ATXN1) 102042808(ATXN1L)

FAB:	101813436(ATXN1L) 101818702(ATXN1)

PHI:	102102505(ATXN1) 102114015(ATXN1L)

PMAJ:

107198809(ATXN1) 107209739(ATXN1L)

CCAE:

111923770(ATXN1) 111934377(ATXN1L)

CCW:	104691416(ATXN1) 104691961(ATXN1L)

ETL:	114064946(ATXN1) 114067597(ATXN1L)

FPG:	101910292(ATXN1) 101918969(ATXN1L)

FCH:	102049807(ATXN1) 102059831(ATXN1L)

CLV:	102084965(ATXN1L) 102094382(ATXN1)

EGZ:	104125491(ATXN1) 104126438(ATXN1L)

NNI:	104021811(ATXN1) 104023603(ATXN1L)

ACUN:

113476522(ATXN1) 113484591(ATXN1L)

PADL:

103919040(ATXN1) 103926389(ATXN1L)

AAM:	106483482(ATXN1) 106498805(ATXN1L)

ASN:	102369249(ATXN1L) 102388038(ATXN1)

AMJ:	102561599(ATXN1L) 102563137(ATXN1)

PSS:	102444413(ATXN1) 102446283(ATXN1L)

CMY:	102929326(ATXN1L) 102948327(ATXN1)

CPIC:

101941635(ATXN1L) 101945614(ATXN1)

ACS:	100554226(atxn1) 103280701(atxn1l)

PVT:	110076285(ATXN1L) 110081690(ATXN1)

PBI:	103051513(ATXN1) 103063732(ATXN1L)

PMUR:

107283500(ATXN1L) 107286333(ATXN1)

TSR:	106541832(ATXN1L) 106550220(ATXN1)

PMUA:

114600882(ATXN1) 114602050(ATXN1L)

GJA:	107114772(ATXN1) 107124708(ATXN1L)

XLA:	100158423(atxn1l.S) 108714055(atxn1l.L) 108719146 108720115

XTR:	100492711(atxn1) 100495371(atxn1l)

NPR:	108796376(ATXN1) 108798646(ATXN1L)

DRE:	101886356 557340(atxn1a) 565841(atxn1b) 571706 793927(atxn1l)

SRX:	107714879 107723489 107724277 107730479 107738335 107743820 107747387(atxn1l) 107754864

SANH:

107657690 107657995 107659133(atxn1l) 107661991 107679905 107696220 107699498 107702111

SGH:	107552998 107561501 107561502 107568056 107568831 107579541 107584245(atxn1) 107593649 107595586

CCAR:

109061607 109061615 109087382 109087395 109098885 109111552 109111553 109113626

IPU:	108254981 108257074(atxn1) 108271097(atxn1l) 108272177 108275782

PHYP:

113526831 113536022(atxn1) 113536677(atxn1l) 113539537 113545599

AMEX:

103023067 103023764(atxn1l) 103029611 103038298 111195425

EEE:	113567747 113575028(atxn1) 113575638 113575775(atxn1l) 113585672

TRU:	101068163(atxn1) 101075149 105416276 105417302(atxn1l) 105417859

TNG:	GSTEN00008986G001 GSTEN00023712G001 GSTEN00034071G001

LCO:	104919470(atxn1l) 104919619 104922223(atxn1) 104940365 109140744

NCC:	104950859(atxn1) 104958731 104960063(atxn1l) 104967096 104968267

MZE:	101468916 101471631(atxn1l) 101474461 101476531 101482109(atxn1)

ONL:	100690947 100709503(atxn1) 100711998(atxn1l) 102077117 102079948

OLA:	101164503 101175307(atxn1l) 105354130 105354405 105355143(atxn1)

XMA:	102217612 102227501(atxn1) 102235511(atxn1l) 111605914 111608380

XCO:	114135904 114141791 114143525 114143569(atxn1l) 114156532(atxn1)

PRET:

103462506(atxn1l) 103465083 103467593 103472419(atxn1) 103478620

CVG:	107081945 107087842(atxn1) 107088140 107095652(atxn1l) 107102024

NFU:	107381367(atxn1l) 107384970 107391167 107393767 107394709(atxn1)

KMR:	108231949(zmp:0000000926) 108241182 108241868(atxn1a) 108242009 108250596(atxn1l)

ALIM:

106515842(atxn1) 106519047 106525182 106529469 106531565(atxn1l)

AOCE:

111567559(atxn1) 111570316 111570506 111577576(atxn1l) 111588743

CSEM:

103378734(atxn1l) 103385430 103388392 103394401(atxn1) 107989214

POV:	109628981 109631778(atxn1) 109633559 109635012 109636898(atxn1l)

LCF:	108885619 108887713(atxn1l) 108891996 108898106(atxn1) 108900173

SDU:	111217411 111221538(atxn1l) 111221815 111222983(atxn1) 111236821

SLAL:

111652778 111655142(atxn1l) 111659271(atxn1) 111670935 111672195

HCQ:	109518016 109525968(atxn1l) 109528012 109528550

BPEC:

110164785 110167219(atxn1) 110171134 110171698 110175309(atxn1l)

MALB:

109955967 109958692(atxn1) 109966096 109966152(atxn1l) 109967315

SASA:

106565947 106566744 106570575 106571912 106582792 106587334(atxn1l) 106588811 106597954

OTW:	112215772 112219525 112222186 112241190 112249177 112264201 112264448

SALP:

111968699 111969375 111974228 111977063 112068877 112074801 112079549

ELS:	105006212 105012484(atxn1) 105016753(atxn1l) 105017335 105030893

SFM:	108919295(atxn1) 108934683(atxn1l) 108936893 108940667

PKI:	111832941(atxn1l) 111840574 111843838 111850455

LCM:	102350118(ATXN1) 102351636(ATXN1L)

CMK:	103175987(atxn1l) 103184552(atxn1)

RTP:	109919494(atxn1l) 109931151(atxn1)

BFO:

SPU:

APLC:

SKO:

DME:	Dmel_CG4547(Atx-1)

DER:

6551642

DSE:

6612200

DSI:	Dsimw501_GD16817(Dsim_GD16817)

DYA:	Dyak_GE16776

DAN:

6503851

DSR:

110180434

DPO:	Dpse_GA23042

DPE:

113566672

DMN:

108164655

DWI:

6644604

DGR:	Dgri_GH24531

DMO:	Dmoj_GI21611

DAZ:

DNV:

DHE:

DVI:

MDE:

LCQ:

AAG:

CQU:	CpipJ_CPIJ003191

TCA:

DPA:

ATD:

NVL:

BMOR:

BMAN:

DPL:	KGM_213544

PMAC:

PRAP:

HAW:

TNL:

API:

DNX:

AGS:

RMD:

BTAB:

CLEC:

ZNE:

CSCU:

PTEP:

BMY:

LOA:	LOAG_17592

CRG:

MYI:

OBI:

LAK:

NVE:

EPA:

ADF:

AMIL:

PDAM:

SPIS:

Reference

PMID:16121196

Authors

Mizutani A, Wang L, Rajan H, Vig PJ, Alaynick WA, Thaler JP, Tsai CC

Title

Boat, an AXH domain protein, suppresses the cytotoxicity of mutant ataxin-1.

Journal

EMBO J 24:3339-51 (2005)
DOI:10.1038/sj.emboj.7600785

Sequence

[hsa:6310 342371]

LinkDB

DBGET integrated database retrieval system