KEGG   Loxodonta africana (African savanna elephant): 100653532
Entry
100653532         CDS       T04351                                 

Gene name
ADCY6
Definition
(RefSeq) adenylate cyclase type 6 isoform X1
  KO
K08046  adenylate cyclase 6 [EC:4.6.1.1]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav00230  Purine metabolism
lav01100  Metabolic pathways
lav01522  Endocrine resistance
lav04015  Rap1 signaling pathway
lav04022  cGMP-PKG signaling pathway
lav04024  cAMP signaling pathway
lav04062  Chemokine signaling pathway
lav04072  Phospholipase D signaling pathway
lav04114  Oocyte meiosis
lav04211  Longevity regulating pathway
lav04213  Longevity regulating pathway - multiple species
lav04261  Adrenergic signaling in cardiomyocytes
lav04270  Vascular smooth muscle contraction
lav04371  Apelin signaling pathway
lav04540  Gap junction
lav04611  Platelet activation
lav04713  Circadian entrainment
lav04714  Thermogenesis
lav04723  Retrograde endocannabinoid signaling
lav04724  Glutamatergic synapse
lav04725  Cholinergic synapse
lav04727  GABAergic synapse
lav04742  Taste transduction
lav04750  Inflammatory mediator regulation of TRP channels
lav04911  Insulin secretion
lav04912  GnRH signaling pathway
lav04913  Ovarian steroidogenesis
lav04914  Progesterone-mediated oocyte maturation
lav04915  Estrogen signaling pathway
lav04916  Melanogenesis
lav04918  Thyroid hormone synthesis
lav04921  Oxytocin signaling pathway
lav04923  Regulation of lipolysis in adipocytes
lav04924  Renin secretion
lav04925  Aldosterone synthesis and secretion
lav04926  Relaxin signaling pathway
lav04927  Cortisol synthesis and secretion
lav04928  Parathyroid hormone synthesis, secretion and action
lav04934  Cushing syndrome
lav04935  Growth hormone synthesis, secretion and action
lav04961  Endocrine and other factor-regulated calcium reabsorption
lav04962  Vasopressin-regulated water reabsorption
lav04970  Salivary secretion
lav04971  Gastric acid secretion
lav04972  Pancreatic secretion
lav04976  Bile secretion
lav05032  Morphine addiction
lav05163  Human cytomegalovirus infection
lav05166  Human T-cell leukemia virus 1 infection
lav05200  Pathways in cancer
lav05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:lav00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    100653532 (ADCY6)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100653532 (ADCY6)
   04371 Apelin signaling pathway
    100653532 (ADCY6)
   04072 Phospholipase D signaling pathway
    100653532 (ADCY6)
   04024 cAMP signaling pathway
    100653532 (ADCY6)
   04022 cGMP-PKG signaling pathway
    100653532 (ADCY6)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100653532 (ADCY6)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    100653532 (ADCY6)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100653532 (ADCY6)
   04062 Chemokine signaling pathway
    100653532 (ADCY6)
  09152 Endocrine system
   04911 Insulin secretion
    100653532 (ADCY6)
   04923 Regulation of lipolysis in adipocytes
    100653532 (ADCY6)
   04912 GnRH signaling pathway
    100653532 (ADCY6)
   04913 Ovarian steroidogenesis
    100653532 (ADCY6)
   04915 Estrogen signaling pathway
    100653532 (ADCY6)
   04914 Progesterone-mediated oocyte maturation
    100653532 (ADCY6)
   04921 Oxytocin signaling pathway
    100653532 (ADCY6)
   04926 Relaxin signaling pathway
    100653532 (ADCY6)
   04935 Growth hormone synthesis, secretion and action
    100653532 (ADCY6)
   04918 Thyroid hormone synthesis
    100653532 (ADCY6)
   04928 Parathyroid hormone synthesis, secretion and action
    100653532 (ADCY6)
   04916 Melanogenesis
    100653532 (ADCY6)
   04924 Renin secretion
    100653532 (ADCY6)
   04925 Aldosterone synthesis and secretion
    100653532 (ADCY6)
   04927 Cortisol synthesis and secretion
    100653532 (ADCY6)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100653532 (ADCY6)
   04270 Vascular smooth muscle contraction
    100653532 (ADCY6)
  09154 Digestive system
   04970 Salivary secretion
    100653532 (ADCY6)
   04971 Gastric acid secretion
    100653532 (ADCY6)
   04972 Pancreatic secretion
    100653532 (ADCY6)
   04976 Bile secretion
    100653532 (ADCY6)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    100653532 (ADCY6)
   04961 Endocrine and other factor-regulated calcium reabsorption
    100653532 (ADCY6)
  09156 Nervous system
   04724 Glutamatergic synapse
    100653532 (ADCY6)
   04727 GABAergic synapse
    100653532 (ADCY6)
   04725 Cholinergic synapse
    100653532 (ADCY6)
   04723 Retrograde endocannabinoid signaling
    100653532 (ADCY6)
  09157 Sensory system
   04742 Taste transduction
    100653532 (ADCY6)
   04750 Inflammatory mediator regulation of TRP channels
    100653532 (ADCY6)
  09149 Aging
   04211 Longevity regulating pathway
    100653532 (ADCY6)
   04213 Longevity regulating pathway - multiple species
    100653532 (ADCY6)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100653532 (ADCY6)
   04714 Thermogenesis
    100653532 (ADCY6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100653532 (ADCY6)
  09165 Substance dependence
   05032 Morphine addiction
    100653532 (ADCY6)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    100653532 (ADCY6)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100653532 (ADCY6)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100653532 (ADCY6)
   05163 Human cytomegalovirus infection
    100653532 (ADCY6)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100653532 (ADCY6)
Enzymes [BR:lav01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     100653532 (ADCY6)
SSDB
Motif
Pfam: AC_N Guanylate_cyc DUF1053 HNOBA TBK1_ULD Shisa
Other DBs
NCBI-GeneID: 100653532
NCBI-ProteinID: XP_023411593
LinkDB
Position
Unknown
AA seq 1180 aa
MVVLIPSPSFPPSSMSWFSGLLVPKVDERKTAWGERNGQKRPRRGTRTSGLCTPHYMSCL
QDAEPPSPTPAAPPRCPWQEEGFIRRGGPGKGTELGLRAVALGFEDTEATVAVGVAELAP
NMVPRSKGSCWHRLVQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLTAVLLA
FHAVPARPQPAYVALLACAATLFVALMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGAL
AATPHSPSVGLWCPVFFVYITYTLLPIRMRAAVFSGLGLSTLHLILAWQLNRGDAFLWKQ
LGANVLLFLCTNVIGICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQ
HVAMEMKEDINTKKEDMMFHKIYIQKHDNVSILFADIEGFTGLASQCTAQELVMTLNELF
ARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGMDMIEAISLVREVTGVN
VNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLEYLNGDY
EVELGRGGERNAYLKEQHIETFLILGASQKRKEEKAMLAKLQRTRANSMEGLMPRWVPDR
AFSRTKDSKAFRQMGIDDSSKDNRGAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRF
LLTFQREDLEKKYSRKVDPRFGAYVACALLVFCFICFIQLLVFPHSTLMLGIYASTFLLL
LITVLTCAVYSCGSLFPKALQHLSRNIVRSRAHSTAVGIFSVLLVFTSATANMFTCNHTP
IRTCAARMLNLTPADITACHLQQLNYSLGLDAPLCEGTAPTCNFPEYFVGNMLLSLLASS
VFLHISSIGKLAMILVLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASSNETFDGLDCPA
PGRVALKYMTPVILLVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLL
HNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLL
NEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLME
QMKHINEHSFNNFQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQV
TTDLYQVLASKGYQLECRGVVKVKGKGEMTTYFLNGGPSS
NT seq 3543 nt   +upstreamnt  +downstreamnt
atggtggtattaataccatctccttcctttcctcccagcagcatgtcgtggtttagtggc
ctcctggttcccaaagtggatgaacggaaaacagcctggggtgaacgcaatgggcaaaag
cgtccgcgccgcgggacacggaccagtggcctctgcacgccccactatatgagctgcctc
caggatgcagagcctcccagccctactcctgcagctccccctcggtgcccctggcaggaa
gaaggcttcatccgcaggggtggcccaggcaagggcacagagctggggctgcgggcggtg
gccctgggctttgaggacacagaggcaacagtggcggtaggggtggccgagctggcgccc
aacatggtgccgaggagcaagggatcctgctggcaccgtctggtgcaggtattccagtca
aagcagttccgctctgccaaactggagcgcctgtaccagcggtacttcttccagatgaac
cagagcagcctgacgctgctgatggcggtgctggtactgctcacggctgtgctgctggcc
ttccacgccgtgcctgcccgccctcagcctgcctacgtggccctgctggcctgtgctgcc
accctcttcgtggctctcatggtggtgtgtaaccgacatagctttcgccaggactccatg
tgggtggtgagctacgtggtgctaggcatcctggcagctgtgcaggttgggggggccctg
gcagccacccctcacagcccctctgtaggcctctggtgccctgtgttctttgtctacatc
acctacacgctcctacccatccgcatgagggcggccgtcttcagtggcctgggtctctcc
accctgcatttgatcttggcctggcaactcaaccgtggagatgccttcctctggaagcag
ctcggtgccaacgtactgcttttcctctgcaccaatgtcattggcatctgcacacactac
ccggctgaggtgtctcagcgccaggcctttcaggagacccgtggctacatccaggcccgg
ctgcacctgcagcatgagaatcggcagcaggagcggctgctgctgtcagtgttgccccag
catgttgccatggagatgaaagaagacatcaacactaaaaaagaagacatgatgttccac
aagatctacatccagaagcatgacaacgtcagcatactgtttgctgacatcgaaggcttc
accggcttggcctcccagtgcaccgcacaagagctggtcatgaccctgaatgagctcttc
gcccgctttgacaagctggccgcggaaaatcattgcctgaggatcaagattttaggggat
tgctactactgtgtgtcagggctgccggaggcccgggcagaccatgcccactgctgtgtg
gagatgggaatggacatgatcgaggccatctcgctggtgcgcgaagtgacaggtgtgaat
gtgaatatgcgcgtgggcatccacagtgggcgtgtgcactgcggtgtcctcggccttcgg
aaatggcagtttgatgtgtggtccaatgatgtgaccctggccaaccacatggaggccggg
ggccgggccggccgcatccacatcactcgggccacgctggagtacctgaatggggactac
gaggtggagttgggccgaggtggggagcgcaacgcatacctcaaggagcagcacattgag
accttcctcatcctgggcgccagccagaagcggaaagaggagaaggccatgctggccaag
ttgcaacggacacgggccaactccatggaggggctgatgccacgctgggtgcccgaccgt
gccttttcccgtaccaaggactccaaagctttccgccagatgggcattgatgattccagc
aaagacaaccggggtgcccaagacgccctgaaccccgaggatgaggtagacgagttcctg
ggccgtgccattgatgcacgtagcattgaccagctccgcaaggaccacgtgcgccggttc
ctgctcaccttccagagagaagaccttgagaagaagtactcgcggaaggtggatccccgc
ttcggagcctacgttgcctgtgccttgttggtcttctgctttatctgcttcatccagctc
ctcgtcttcccacactcaaccctgatgcttgggatctatgccagtaccttcctgctgttg
ctgatcactgtgctgacctgtgctgtgtactcttgtggttcactgttccctaaggccctg
caacatctgtcccgcaatatcgtccgctctcgggcacacagcactgcggttggcatcttt
tcagttctgcttgtcttcacctctgccactgccaacatgttcacctgtaaccacaccccc
atccggacctgtgcagcccggatgctgaatttaacacctgccgacatcaccgcctgccac
ctgcagcagctcaattactctctgggcctggatgctcccctgtgtgagggcaccgcacct
acctgcaacttccccgagtacttcgttggaaacatgctactgagtctcttggccagctct
gtcttcctacatatcagcagcatcgggaagttggccatgatccttgtcctggggctcatc
tatttggtgctgcttctgctgggtcccccggccaccatctttgacaactatgacctactg
cttggtgtccatggcttagcttcttccaacgagaccttcgatgggctagactgcccagct
cccgggagggtggcactcaagtatatgacccctgtgattctgctggtgtttgccctggcg
ctctatctgcatgcccagcaggtggagtcaactgcccgcttggacttcctctggaaactg
caggcaacaggggagaaggaggagatggaagagctccaggcctacaaccggcgactgctg
cacaacatcctgcccaaggatgtggccgcccactttctggcccgcgagcgccggaatgat
gagctttactatcagtcctgtgagtgtgtggctgtcatgtttgcttccatcgccaacttc
tctgagttttatgtggagctggaggcaaacaacgagggcgtagagtgcctacggctgctc
aacgagatcatcgcggactttgatgagatcatcagtgaggagcggttccggcagctggag
aaaatcaagacaattggcagcacctacatggctgcctcggggctgaacgccagcacctac
gatcaggtgggccgctcccacatcactgcccttgccgactatgccatgcggctcatggag
cagatgaagcacatcaatgagcactccttcaacaatttccagatgaagattggactgaac
atgggcccagtcgtagcaggtgtcattggggctcggaagccgcagtatgacatctggggg
aacacagtgaatgtctctagccgtatggacagcacaggggttcctgaccgaatccaggtg
accacggacctgtaccaggttttagcctccaagggctaccagctggagtgtcgaggggtg
gtcaaggtgaagggcaagggggagatgaccacctacttcctcaatgggggccccagcagt
tag

KEGG   Loxodonta africana (African savanna elephant): 100653771
Entry
100653771         CDS       T04351                                 

Gene name
ADCY7
Definition
(RefSeq) adenylate cyclase type 7 isoform X1
  KO
K08047  adenylate cyclase 7 [EC:4.6.1.1]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav00230  Purine metabolism
lav01100  Metabolic pathways
lav01522  Endocrine resistance
lav04015  Rap1 signaling pathway
lav04020  Calcium signaling pathway
lav04022  cGMP-PKG signaling pathway
lav04024  cAMP signaling pathway
lav04062  Chemokine signaling pathway
lav04072  Phospholipase D signaling pathway
lav04114  Oocyte meiosis
lav04211  Longevity regulating pathway
lav04213  Longevity regulating pathway - multiple species
lav04261  Adrenergic signaling in cardiomyocytes
lav04270  Vascular smooth muscle contraction
lav04371  Apelin signaling pathway
lav04540  Gap junction
lav04611  Platelet activation
lav04713  Circadian entrainment
lav04714  Thermogenesis
lav04723  Retrograde endocannabinoid signaling
lav04724  Glutamatergic synapse
lav04725  Cholinergic synapse
lav04727  GABAergic synapse
lav04750  Inflammatory mediator regulation of TRP channels
lav04911  Insulin secretion
lav04912  GnRH signaling pathway
lav04913  Ovarian steroidogenesis
lav04914  Progesterone-mediated oocyte maturation
lav04915  Estrogen signaling pathway
lav04916  Melanogenesis
lav04918  Thyroid hormone synthesis
lav04921  Oxytocin signaling pathway
lav04923  Regulation of lipolysis in adipocytes
lav04925  Aldosterone synthesis and secretion
lav04926  Relaxin signaling pathway
lav04927  Cortisol synthesis and secretion
lav04928  Parathyroid hormone synthesis, secretion and action
lav04934  Cushing syndrome
lav04935  Growth hormone synthesis, secretion and action
lav04970  Salivary secretion
lav04971  Gastric acid secretion
lav04972  Pancreatic secretion
lav04976  Bile secretion
lav05032  Morphine addiction
lav05163  Human cytomegalovirus infection
lav05166  Human T-cell leukemia virus 1 infection
lav05200  Pathways in cancer
lav05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:lav00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    100653771 (ADCY7)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100653771 (ADCY7)
   04371 Apelin signaling pathway
    100653771 (ADCY7)
   04020 Calcium signaling pathway
    100653771 (ADCY7)
   04072 Phospholipase D signaling pathway
    100653771 (ADCY7)
   04024 cAMP signaling pathway
    100653771 (ADCY7)
   04022 cGMP-PKG signaling pathway
    100653771 (ADCY7)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100653771 (ADCY7)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    100653771 (ADCY7)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100653771 (ADCY7)
   04062 Chemokine signaling pathway
    100653771 (ADCY7)
  09152 Endocrine system
   04911 Insulin secretion
    100653771 (ADCY7)
   04923 Regulation of lipolysis in adipocytes
    100653771 (ADCY7)
   04912 GnRH signaling pathway
    100653771 (ADCY7)
   04913 Ovarian steroidogenesis
    100653771 (ADCY7)
   04915 Estrogen signaling pathway
    100653771 (ADCY7)
   04914 Progesterone-mediated oocyte maturation
    100653771 (ADCY7)
   04921 Oxytocin signaling pathway
    100653771 (ADCY7)
   04926 Relaxin signaling pathway
    100653771 (ADCY7)
   04935 Growth hormone synthesis, secretion and action
    100653771 (ADCY7)
   04918 Thyroid hormone synthesis
    100653771 (ADCY7)
   04928 Parathyroid hormone synthesis, secretion and action
    100653771 (ADCY7)
   04916 Melanogenesis
    100653771 (ADCY7)
   04925 Aldosterone synthesis and secretion
    100653771 (ADCY7)
   04927 Cortisol synthesis and secretion
    100653771 (ADCY7)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100653771 (ADCY7)
   04270 Vascular smooth muscle contraction
    100653771 (ADCY7)
  09154 Digestive system
   04970 Salivary secretion
    100653771 (ADCY7)
   04971 Gastric acid secretion
    100653771 (ADCY7)
   04972 Pancreatic secretion
    100653771 (ADCY7)
   04976 Bile secretion
    100653771 (ADCY7)
  09156 Nervous system
   04724 Glutamatergic synapse
    100653771 (ADCY7)
   04727 GABAergic synapse
    100653771 (ADCY7)
   04725 Cholinergic synapse
    100653771 (ADCY7)
   04723 Retrograde endocannabinoid signaling
    100653771 (ADCY7)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100653771 (ADCY7)
  09149 Aging
   04211 Longevity regulating pathway
    100653771 (ADCY7)
   04213 Longevity regulating pathway - multiple species
    100653771 (ADCY7)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100653771 (ADCY7)
   04714 Thermogenesis
    100653771 (ADCY7)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100653771 (ADCY7)
  09165 Substance dependence
   05032 Morphine addiction
    100653771 (ADCY7)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    100653771 (ADCY7)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100653771 (ADCY7)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100653771 (ADCY7)
   05163 Human cytomegalovirus infection
    100653771 (ADCY7)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100653771 (ADCY7)
Enzymes [BR:lav01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     100653771 (ADCY7)
SSDB
Motif
Pfam: Guanylate_cyc AC_N DUF1053
Other DBs
NCBI-GeneID: 100653771
NCBI-ProteinID: XP_023411382
LinkDB
Position
Unknown
AA seq 1090 aa
MPAKGRYFLNEGEEGPDQDALYERYSLTSQRGPLLLTFLLVAIAACTALIVIEFINWDPS
KLKTLLGTAVVVLVVFVALYLLVYVDCLVRRGLRALALLTWACLMTLGYVLLYDSRMKGA
CSWEQVPFFLFVIFVVYTLLPFSMWGAVAVGVVSTVSHLLVLGILLGAHKMPSDHIVLKL
LANAIIFLCGNLTGAFHKHRMQDASRDLFTYTVKCIQVRSKLRIEKRQQENLLLSVLPAH
ISMGMKLAIIERLKEHRDRRYMPDNNFHSLYVKRHQNVSILYADIVGFTQLASDCSPKEL
VVMLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCEAIKQ
VREATGVDINMRVGIHSGNVLCGVIGLLKWQYDVWSHDVSLANRMEASGVPGRVHITEAT
LNHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPCQHLPRPKGDAALKMRA
SVRMTRYLESWGAARPFAHLNHRESVSVSETPDPNSRRPRAIPLRRHRTPDKSASLKGRS
EDDSYNDEMWSAIEGLTSTRCGPPHSCAAAPRFCCSRSDDFHTCTWVSIFQEKGLEREYR
LAPIPRARHYFACAGLVFLCILLIHVLLMPRMAALGVSFGLVACVLGLVLGLSFADQFLR
CCPAWGMLRAISERVETQSLLRVSLAIVTISSLLTIAIISLPLLPVPALGPPGGNETSRN
TVSSQTSCELLLHYTSSCILGFIACSVFLWMSLELKFVLLTVALVAYLVLFNISPCWQWA
CCSHSLGNLTESNGTLSSSCPWSDLKTMINFYLVLFYVTLVMLSMQTDYYCRLDCLWKKK
FKKEQEEFETMENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKV
FYTECDINKEGLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVTSGHE
NQDLERQHAQIGIMVEFSLALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYD
IWGNTVNVASRMESTGELGKIQVTEETCTILQGLGYSCECRGLINVKGKGELTTYFVCTD
TAKFQGLGLN
NT seq 3273 nt   +upstreamnt  +downstreamnt
atgccagccaaggggcgctatttcctcaacgagggtgaggagggcccagaccaggatgcg
ctgtatgagaggtatagcctcaccagccagcgcgggccgctgctgctcacattcctgctg
gtggctatcgcggcctgcactgccctcatcgtcatcgagttcatcaactgggacccctcc
aaactcaagactctcctggggacggcggtcgtggtgcttgtcgtgtttgttgccctctac
ctgctggtgtatgtcgactgccttgtgcggcgggggctcagggccctggcgctgctcacc
tgggcctgcctcatgacgctgggttacgtgctgctgtacgactcacggatgaagggggcc
tgctcctgggagcaggtgcccttcttcctgtttgtcatcttcgtggtgtacacgctgctg
cccttcagcatgtggggggccgtcgcagtgggggtcgtctccactgtctcccacctcctc
gtgctcggcatcctcctgggggcccacaagatgcctagtgaccacatagtgctgaagctg
ctggccaatgccatcatcttcttgtgtgggaacctgactggcgccttccacaagcaccgg
atgcaggatgcctccagagacctgttcacctacactgtgaagtgcatccaggtccggagc
aagctgcgcatcgagaagcggcagcaggagaacctgctgctctcggtgctgccagcccac
atctccatgggcatgaagctggccatcattgagcgcctcaaggagcacagggaccgccgc
tacatgcccgacaacaacttccacagcctgtatgtcaagcggcaccagaacgtcagcatc
ctctacgcagacattgtgggcttcacgcagctggccagtgactgctcccccaaggagctg
gtggtgatgcttaacgagctctttggaaagttcgaccagattgccaaggccaacgagtgc
atgcggatcaagatcctgggtgactgctattactgcgtgtcgggcctgcctgtgtccctg
cccactcatgcccggaactgcgtgaagatggggctggacatgtgtgaggccatcaagcag
gtgcgggaggccacgggtgtggacatcaacatgcgcgtgggcatccactccgggaacgtg
ctgtgcggtgtcatcgggctgctcaagtggcagtatgacgtatggtcccacgacgtgtcc
ctggccaacaggatggaggcatctggagtccccggccgggtgcacatcacggaggcgacg
ctgaaccacctggacaaggcgtacgaagtggaggatgggcacgggcagcagagggacccc
tacctgaaggagatgaatatccgcacctacctggtcatcgacccccggagccagcagcca
cctccgccctgccagcacctccccaggcccaagggggacgcagctctgaagatgcgggcg
tcagtgcggatgacccgctacctggagtcctggggtgccgcgcggcccttcgcgcacctc
aaccatcgcgagagcgtgagcgtcagtgagacccctgaccccaacagccggaggcccagg
gccattcctttgcggcgccaccggaccccagacaaaagtgcgtctctcaaggggcggtcg
gaggatgactcctacaacgatgagatgtggtcggccatcgaggggctcacttccacaagg
tgtggcccccctcactcctgtgctgccgcccccaggttctgctgctccaggtcagatgac
ttccacacctgcacctgggtgtccatcttccaggagaagggccttgagcgagagtaccgc
ctggcacccatcccccgggcccgccactacttcgcctgtgccggcctcgtcttcctctgc
atcctgctcatccatgtcctgctgatgcccaggatggcggctctgggtgtgtcctttggg
ctggtggcctgtgtgctggggctagtgctgggcctgtcctttgctgatcagttcttgagg
tgctgcccagcctgggggatgctccgggccatctctgagagggtggagacacagtccctg
ctgagggtgtccctggccatcgtgaccatcagcagcctgctcaccattgccatcatcagc
ctgccgctgctccctgtcccagcactgggaccacctggtgggaacgagacgagccggaac
actgtgagcagccagacctcatgtgagctgctgctgcattacaccagcagctgcatcctg
ggcttcattgcttgctccgtcttcttgtggatgagcctggagctgaagttcgtgctgctg
accgtggccttggtggcctacctggtgctctttaacatctctccgtgctggcagtgggcc
tgctgcagccacagcctgggcaacctcacggagagcaacggcaccctcagctcctcttgt
ccatggagtgatctgaagacaatgattaatttctacctggttctgttctatgtcaccctc
gtcatgctctccatgcagactgactactactgccgtctggactgtttgtggaagaagaag
ttcaagaaggagcaggaggagtttgagaccatggagaatgtgaaccgccttcttctggag
aacgtcctgccagcccatgtggccgcccacttcattggcgacaagttaaatgaggactgg
taccaccagtcgtatgactgcgtctgtgtcatgtttgcgtccgtgccggatttcaaagtg
ttctataccgagtgcgacatcaacaaggaagggctggagtgcctgcgcctgctgaacgag
atcattgcggactttgacgagctgctgttaaagcccaagttcagtggggtggagaagatc
aagaccatcggcagcacatacatggcagcagcggggctcagcgtcacctcagggcatgag
aaccaggacctggagcggcagcacgcccagatcggcatcatggtggagttcagcctcgcc
ctgatgagcaagctggacggcatcaacaggcactccttcaactccttccgcctccgtgtc
ggcataaaccatgggcccgtgattgctggggtgatcggggcgcggaaacctcagtatgac
atctggggaaacacggtcaatgttgccagccgaatggagagcactggggaacttgggaaa
atccaggttactgaggagacatgcaccatcctgcagggactgggctactcctgtgagtgc
cgcggactgattaacgtcaaaggcaagggcgaactgacgacttacttcgtctgcacagac
actgccaagttccaagggctggggctgaactga

KEGG   Loxodonta africana (African savanna elephant): 100655094
Entry
100655094         CDS       T04351                                 

Gene name
ADCY10
Definition
(RefSeq) adenylate cyclase type 10 isoform X1
  KO
K11265  adenylate cyclase 10 [EC:4.6.1.1]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav00230  Purine metabolism
lav01100  Metabolic pathways
lav04024  cAMP signaling pathway
lav04371  Apelin signaling pathway
lav04713  Circadian entrainment
lav04714  Thermogenesis
lav04935  Growth hormone synthesis, secretion and action
Brite
KEGG Orthology (KO) [BR:lav00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    100655094 (ADCY10)
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    100655094 (ADCY10)
   04024 cAMP signaling pathway
    100655094 (ADCY10)
 09150 Organismal Systems
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    100655094 (ADCY10)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100655094 (ADCY10)
   04714 Thermogenesis
    100655094 (ADCY10)
Enzymes [BR:lav01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     100655094 (ADCY10)
SSDB
Motif
Pfam: Guanylate_cyc AAA_16 AAA_22 DUF2075 AAA_14 AAA_30 AAA_19
Other DBs
NCBI-GeneID: 100655094
NCBI-ProteinID: XP_003414943
LinkDB
Position
Unknown
AA seq 1610 aa
MSTRIEDSQDRAIVKIAAHLPDLIVYGDFSPERPSVKYFDGVLMFVDISGFTAMTEKFSR
AMYMDRGAEQLVEILNHYISAIVEKVLIFGGDILKFAGDALLALWKVERKQLKNIITVVI
KCSLEIHGLFETQESEEGLDIRVKIGLSAGHISILVFGDETRNYFLVIGQAVDDVRFAQN
MAQMNDVILSPNCWQLCDRNMVEIERIPDQRAVKVNFLKPPPTFNFDEFFAKCMHFMDYY
PSGDNKNVLRLACMLESDPELELSLQKYVMESILKQIDDKQLRGYLSELRPVTIVFVNLM
FRDHDKPEDIGQAIQDACVHITSVLRVFRGQINKVFMFDKGCSFLCVFGFPGEKAPDEVT
HALESAVDIFDFCSQVHRIQSVSIGVASGIVFCGIVGHSVRHEYTVIGQKVNIAARMMMY
YPGIVTCDSVTYNNSNLPAYFFKELPKKVMKGVADSGPVYQCLGLNEKVMFGMAYLICNR
NEGYPLLGRDKEIKYFMCTMKEYLMSNCSRVLMYEGLPGYGKSQILMEIDYLAQGENHRT
IAIALTKISYHQNFYTIQILMANVLGLDTCKHYKERQSNLQNKVSTLLDEKFHCLLNDIF
HVQFPISREASRMSSSRKQRQLEALFMKILEQTVKEERIIFIIDEAQFVDSASWAFMEKL
IRTVPIFIIMSLSPFTDVPCIHASSIMKNRNTTYVTLGAVQPKDILNKICLDLNVSGIRK
ELDSYLVEGSCGIPFYCEELLKDLDHHRVLIFQPMESEEKANVNWNNLFKNFTKPTEELN
MLVPSSEEGNEEVCNIAGGVRLKNLSPPASLKEISLVQLDSMSLSHQMLVRCAAIIGQTF
TTELLFEILPCWNMKMMIKALATLVESNIFDCFRNGKELRMALKQHAASFEVHFRSLSLK
PSEGMALGEEEELRELESEVIECHIIRFCKPMMQKTAYELWLKDQKKAMHLKCARFLEEN
AHKCDHCRSGDFIPYHHFTVDIRLNTLDVDTIKKMAKAHGIKTEEEITFSKSEIPKKSNI
FPDDLSSEEIREKILGFFDIIITKMKTTEEDIIPLESCQCEEILEIVILPLAYHFLALGE
NNKALYYFLEIASAYLILNDNYMAYMYLNEGERMLKTLRKQKSWSQTFESATFFSLKGQV
CFNMGHMVLAKKMLRKALKLLNRVFPYTLFSLFLHTHIEKNRHFHYLNQQTQESPPHGKK
RLAQLYRQTACFSLLWKIYSSNYFFHYKYYAHLAAMMQVNTALETQDNFQIIKAYLDYSL
HHQLAGYQGIWFKYEIMAMEQIFNLPLKGEGIEIVAYVAETLSNVKLLMGHLDLAIDLGS
RAHKMWALLRNPSKHYLVLCRLSKSLLLKCRYKQLIQVLGWLWDLSVAEEHIFSKAYFYF
VCLDIMLYCGFVYRTFEECLNFIYQNEDNRILKFQSGILLGLYSCGAIWYARLQEWDNFK
IFSNRAKTLVPRRTPTPLYCEGISRYLEGQVLYLQKQIEEQAENAQDSGVELLKNLESLL
AQNTTGPVFYPRLYHLMAYVCILMGDGENCDFFLNTALQISEAHGNLLEKCWLNMSKEWW
YSSSESAEDQWLQTILSLPSWKKIVSGKVNIQDIHKNKFLMRVNILDNPF
NT seq 4833 nt   +upstreamnt  +downstreamnt
atgagtactcgaatagaagactcacaagaccgggccatcgtcaaaatagcagctcattta
ccggacctcattgtctatggagatttctctccagagcgaccttctgtgaaatatttcgat
ggagtcttgatgtttgttgatatttcaggttttactgcaatgactgagaagttcagcagg
gccatgtatatggaccgaggggctgagcagttggtggagatcctcaatcactacataagc
gcaatagtagagaaagtgttaatttttggaggagacatcctaaaatttgcaggtgacgcg
ctgctagccctttggaaggtggaacgaaagcaactgaaaaacattatcacagtggtcatt
aaatgtagcctggagatccacggattgtttgagacccaggagtctgaagaaggcctagat
atccgggtcaagataggactgtctgctggccacatcagcattttggtctttggggatgaa
acacgcaactactttctggtgattggtcaggccgtggatgacgtccgctttgcgcagaac
atggcgcagatgaacgatgtcattctgtcgccaaactgctggcagctctgtgacagaaac
atggttgaaatcgagaggattccagaccagagagcagttaaggttaacttcttaaaacca
ccccctacttttaattttgatgaatttttcgccaagtgtatgcacttcatggattattat
ccttctggtgataacaaaaatgtcctgaggcttgcgtgcatgctggagtctgatcctgaa
ctggagctgtctctacaaaagtatgtaatggagagcattttgaagcagattgatgacaaa
cagcttcggggttatttgtctgagcttcgcccagtgacaattgtgttcgtgaacctgatg
ttcagggaccatgacaaaccagaagacataggccaggccatccaggatgcttgtgtgcac
atcacttctgtcttgagggtattccgaggccaaatcaataaagtcttcatgtttgacaag
ggttgctccttcctctgtgtctttggtttccctggggaaaaggcacctgacgaggtcact
catgctttggaaagtgctgtggatatctttgacttctgctctcaggtgcacagaattcag
agtgtatccatcggggttgccagcgggattgtcttctgtggaattgttggacactctgtg
agacacgagtacacagtcattggtcaaaaggtcaacatagcggccagaatgatgatgtat
tacccaggaatcgtgacctgtgactctgtcacctacaataacagcaacttaccagcctac
ttttttaaagagcttccaaagaaagttatgaagggtgttgcagattctggaccagtctat
cagtgtttgggccttaatgagaaagtcatgtttggtatggcgtacctcatctgcaacaga
aatgagggttaccctttgctgggacgtgataaggagatcaaatacttcatgtgtactatg
aaggaatatttgatgtctaactgtagccgagttctaatgtatgaaggattaccaggatat
ggaaaaagccagatacttatggaaatagattacctggcccaaggtgagaaccacaggact
attgctattgctttgactaagatcagctaccatcaaaatttttataccatccagatactc
atggccaatgtactaggtctggatacttgtaaacattataaagaacggcagtccaacctt
caaaataaagtcagcacactgttggatgaaaagttccactgtcttctcaatgacattttc
catgtccagtttcctatttcacgggaggcttccaggatgagctcctcaagaaagcaaagg
caattggaagcattgtttatgaagatcttggagcaaacagtgaaagaggaaaggattatt
ttcatcattgatgaggcccagtttgtggattcagcctcctgggcctttatggagaagttg
atccgtactgtccctatcttcatcatcatgtccctgtctcccttcacggatgtgccctgt
atacatgccagttctataatgaagaacagaaacaccacctatgtcacccttggtgcagta
cagcctaaagacatcctcaacaagatatgtcttgacctcaatgtgagcggtatccgcaaa
gaactggactcgtacctggtagagggaagctgtgggattccattttactgtgaagaattg
ctaaaagacctcgaccatcatagggtactcattttccaaccgatggagtctgaggaaaag
gcaaatgtgaactggaataacctgttcaagaatttcactaagccaacagaagaattaaat
atgcttgttcccagtagtgaggagggaaatgaagaagtttgtaacatcgctggtggtgtt
agattgaaaaacttgtcacccccagcatcattaaaagaaatctctttggtccagctggac
agcatgagcctttcccaccaaatgttggtgagatgtgcggctattattggccagaccttc
accacagagttgttgtttgagatcctcccttgttggaacatgaagatgatgatcaaggcc
ctggcaaccctagtggaatccaacatctttgattgtttccggaatggcaaggagctccgg
atggctttgaaacagcacgcagcctcatttgaggtgcattttcgctccctgtctctgaag
cccagtgaaggaatggctcttggtgaagaggaagaacttcgagaactagaaagcgaggtg
attgagtgccacatcattcgattctgcaagcctatgatgcagaaaacagcctatgagcta
tggctgaaggaccagaagaaagccatgcacttgaaatgtgcccgttttctagaagaaaat
gctcacaaatgtgaccactgcagaagtggggacttcattccttaccaccacttcacagtg
gacattcgactcaacactttggacgtggataccattaagaagatggctaaggcccatgga
attaaaactgaagaagagatcaccttttccaaatcagagattcctaagaaatctaacata
tttcctgatgatctcagttctgaagaaataagagaaaagatcttgggtttctttgacatc
attataacaaaaatgaagacaactgaggaagacatcatccccctggaatcctgccagtgt
gaggagatcttggagattgtcatcttgcctctggcctaccactttctggctctgggggaa
aacaacaaagccttatattacttcctagaaattgcatctgcttatctcatcttgaatgat
aactatatggcatacatgtatttgaatgagggagagaggatgctgaaaactctcaggaag
caaaaatcttggagtcaaacttttgagtctgccaccttttttagccttaaaggtcaggtc
tgtttcaacatgggccacatggtacttgccaagaaaatgctgaggaaggcactgaagctc
ctcaacagagtctttccttacactttattctctctgtttctccatacccacatcgagaaa
aacagacactttcattatttgaatcagcagacccaagagagcccacctcatgggaagaag
aggttggcacaactttaccggcaaactgcctgcttctccttgctatggaagatttatagc
tcaaattatttttttcactacaagtattatgcccacctagccgctatgatgcaagtgaat
actgcactggaaactcaagataatttccagatcattaaggcgtacctggactattcactg
caccatcagctggctggctaccaaggcatatggttcaagtacgaaatcatggccatggag
cagatcttcaacctccccctgaaaggcgagggcattgaaatcgtggcatatgtggccgaa
acactgagcaacgtcaagctcctgatgggtcatcttgacttggccattgatttaggctcc
cgagcccacaagatgtgggcactgctccgaaatcccagcaaacactatctggtcctctgc
agacttagtaaatctctcctcttgaaatgcagatataagcaattgatccaggtgctgggg
tggctgtgggatctttctgtagcagaggagcacatctttagcaaggcatatttctatttt
gtctgcctggacatcatgctttattgtggctttgtttataggacatttgaagaatgtttg
aatttcatataccaaaatgaagacaacagaatcctcaagttccaaagtggcatcttgctg
ggactttactcgtgtggagcgatctggtatgctaggcttcaagaatgggacaattttaaa
atattttccaatagagctaaaactctagtgccgagaagaaccccgacccctctttactgt
gaaggaatcagtaggtacctggagggacaagttctctaccttcaaaagcaaattgaagaa
caagctgagaatgcccaggacagtggagttgagctactgaagaacttggagagtcttttg
gctcaaaataccactggccctgtcttctacccgaggctctaccacctgatggcctatgtc
tgtatactcatgggggatggggagaactgtgacttcttcctgaacacagccctacagatc
tctgaagcccatgggaatctgctggagaaatgctggctgaacatgagcaaagaatggtgg
tactcgagctctgagtcagcagaagaccagtggctgcaaacaatcttgagtctcccctca
tggaaaaaaatcgtatcaggcaaggttaatatacaggacattcataaaaacaaattcctg
atgagagtcaatatcttggacaaccctttctaa

KEGG   Loxodonta africana (African savanna elephant): 100661616
Entry
100661616         CDS       T04351                                 

Gene name
ADCY8
Definition
(RefSeq) adenylate cyclase type 8
  KO
K08048  adenylate cyclase 8 [EC:4.6.1.1]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav00230  Purine metabolism
lav01100  Metabolic pathways
lav01522  Endocrine resistance
lav04015  Rap1 signaling pathway
lav04020  Calcium signaling pathway
lav04022  cGMP-PKG signaling pathway
lav04024  cAMP signaling pathway
lav04062  Chemokine signaling pathway
lav04072  Phospholipase D signaling pathway
lav04114  Oocyte meiosis
lav04211  Longevity regulating pathway
lav04213  Longevity regulating pathway - multiple species
lav04261  Adrenergic signaling in cardiomyocytes
lav04270  Vascular smooth muscle contraction
lav04371  Apelin signaling pathway
lav04540  Gap junction
lav04611  Platelet activation
lav04713  Circadian entrainment
lav04714  Thermogenesis
lav04720  Long-term potentiation
lav04723  Retrograde endocannabinoid signaling
lav04724  Glutamatergic synapse
lav04725  Cholinergic synapse
lav04727  GABAergic synapse
lav04742  Taste transduction
lav04750  Inflammatory mediator regulation of TRP channels
lav04911  Insulin secretion
lav04912  GnRH signaling pathway
lav04913  Ovarian steroidogenesis
lav04914  Progesterone-mediated oocyte maturation
lav04915  Estrogen signaling pathway
lav04916  Melanogenesis
lav04918  Thyroid hormone synthesis
lav04921  Oxytocin signaling pathway
lav04923  Regulation of lipolysis in adipocytes
lav04925  Aldosterone synthesis and secretion
lav04926  Relaxin signaling pathway
lav04927  Cortisol synthesis and secretion
lav04928  Parathyroid hormone synthesis, secretion and action
lav04934  Cushing syndrome
lav04935  Growth hormone synthesis, secretion and action
lav04970  Salivary secretion
lav04971  Gastric acid secretion
lav04972  Pancreatic secretion
lav04976  Bile secretion
lav05032  Morphine addiction
lav05163  Human cytomegalovirus infection
lav05166  Human T-cell leukemia virus 1 infection
lav05200  Pathways in cancer
lav05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:lav00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    100661616 (ADCY8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100661616 (ADCY8)
   04371 Apelin signaling pathway
    100661616 (ADCY8)
   04020 Calcium signaling pathway
    100661616 (ADCY8)
   04072 Phospholipase D signaling pathway
    100661616 (ADCY8)
   04024 cAMP signaling pathway
    100661616 (ADCY8)
   04022 cGMP-PKG signaling pathway
    100661616 (ADCY8)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100661616 (ADCY8)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    100661616 (ADCY8)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100661616 (ADCY8)
   04062 Chemokine signaling pathway
    100661616 (ADCY8)
  09152 Endocrine system
   04911 Insulin secretion
    100661616 (ADCY8)
   04923 Regulation of lipolysis in adipocytes
    100661616 (ADCY8)
   04912 GnRH signaling pathway
    100661616 (ADCY8)
   04913 Ovarian steroidogenesis
    100661616 (ADCY8)
   04915 Estrogen signaling pathway
    100661616 (ADCY8)
   04914 Progesterone-mediated oocyte maturation
    100661616 (ADCY8)
   04921 Oxytocin signaling pathway
    100661616 (ADCY8)
   04926 Relaxin signaling pathway
    100661616 (ADCY8)
   04935 Growth hormone synthesis, secretion and action
    100661616 (ADCY8)
   04918 Thyroid hormone synthesis
    100661616 (ADCY8)
   04928 Parathyroid hormone synthesis, secretion and action
    100661616 (ADCY8)
   04916 Melanogenesis
    100661616 (ADCY8)
   04925 Aldosterone synthesis and secretion
    100661616 (ADCY8)
   04927 Cortisol synthesis and secretion
    100661616 (ADCY8)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100661616 (ADCY8)
   04270 Vascular smooth muscle contraction
    100661616 (ADCY8)
  09154 Digestive system
   04970 Salivary secretion
    100661616 (ADCY8)
   04971 Gastric acid secretion
    100661616 (ADCY8)
   04972 Pancreatic secretion
    100661616 (ADCY8)
   04976 Bile secretion
    100661616 (ADCY8)
  09156 Nervous system
   04724 Glutamatergic synapse
    100661616 (ADCY8)
   04727 GABAergic synapse
    100661616 (ADCY8)
   04725 Cholinergic synapse
    100661616 (ADCY8)
   04720 Long-term potentiation
    100661616 (ADCY8)
   04723 Retrograde endocannabinoid signaling
    100661616 (ADCY8)
  09157 Sensory system
   04742 Taste transduction
    100661616 (ADCY8)
   04750 Inflammatory mediator regulation of TRP channels
    100661616 (ADCY8)
  09149 Aging
   04211 Longevity regulating pathway
    100661616 (ADCY8)
   04213 Longevity regulating pathway - multiple species
    100661616 (ADCY8)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100661616 (ADCY8)
   04714 Thermogenesis
    100661616 (ADCY8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100661616 (ADCY8)
  09165 Substance dependence
   05032 Morphine addiction
    100661616 (ADCY8)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    100661616 (ADCY8)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100661616 (ADCY8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100661616 (ADCY8)
   05163 Human cytomegalovirus infection
    100661616 (ADCY8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100661616 (ADCY8)
Enzymes [BR:lav01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     100661616 (ADCY8)
SSDB
Motif
Pfam: Guanylate_cyc DUF1053 AC_N TBK1_ULD
Other DBs
NCBI-GeneID: 100661616
NCBI-ProteinID: XP_010586798
LinkDB
Position
Unknown
AA seq 1067 aa
MNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTYLQY
SGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLLQV
ILQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLE
TENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFT
NLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVE
MGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGG
IPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEDSLLSLPEDIVKE
SVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGP
EEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLL
FITAIQSLLPSSRVMPLAIQFSVLIMLHSALVLITTAEDYKCLPLVLRKTCCWINETYLA
RNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVLAM
VTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDNLNHSGEDFLGTKEASLLL
MAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFL
EKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLSE
DRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWDHLCALADFSLALSESIQEINKHSFNN
FELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQG
FAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLN
RQRQKQLLNENNNTGIIKAHYNRRTLLTPSGPEPGAQAEGTDKSDLP
NT seq 3204 nt   +upstreamnt  +downstreamnt
atgaacgtgctggacgtgctgactaaactcaccctcttggttctccacttgagcctggcc
tcggcacccatggacccgctcaagggcattctgttgggtttcttcaccggcatcgaggtg
gtaatctgcgccctggtggtggtcaggaaggacaccacctcacacacgtacctgcagtac
agcggcgtggtcacctgggtggccatgaccacccaaatcctggcagcaggccttggctat
gggctcctgggtgacggcatcggttacgtgctcttcacgctcttcgccacctacagcatg
ctgccgctgcccctcacctgggccatcctggccggcctgggcacctcgctgctccaggtg
atcctccaagtggtcatccccagactggcggtcatttccatcaaccaggtggtggcccag
gcagtgttattcatgtgtatgaacacagctgggatcttcatcagttacctgtcagaccgg
gcccagcgccaagccttcctggagactcggaggtgtgtggaggccaggctgcgcctggaa
acagagaaccagagacaggagcggcttgtgctgtctgtgctccccaggtttgttgtcctg
gaaatgatcaacgacatgactaatgtggaagacgagcacctgcagcaccagttccaccgg
atctacatccaccgctatgagaatgtcagtattcttttcgcagatgttaaaggatttacc
aacctctccacgaccttgtctgctcaggagctggtcaggatgctcaacgagctctttgcc
agatttgatcgcctggcccatgagcatcactgtcttcgcattaaaatcctgggagactgc
tactattgcgtttccggacttcctgaaccccgccaggaccacgcccactgctgtgttgaa
atgggcctcagcatgattaaaaccatcaggtatgtgcgatcaaggacaaagcatgacgtt
gacatgcggattggaatccactcaggctcagtgctctgtggcgtgttgggcctgcggaag
tggcagtttgatgtctggtcttgggatgtggacattgcgaacaaactcgaatctggagga
atccctgggaggattcacatttccaaggccacactggactgcctcaatggtgactacaat
gtggaagaggggcacggtaaagagaggaatgaattcctgaggaagcataatatagagacc
tatttaattaagcagcctgaggacagtctgctgtctttgcccgaagacattgtcaaggag
tcggtgagctcctcggacaggagaaacagtggagcaaccttcacagaagggtcctggagc
cccgagctgccctttgataacatagtggggaaacagaacactctggctgccctaacaaga
aattcaataaatctgcttccaaaccatctcgcacaagctttgcatgtccagtcggggcct
gaggaaattaacaagagaatagaacataccatcgacttgcggagtggcgataaattgcga
agagagcatatcaagccattctcactgatgtttaaagactccagcctggagcacaagtac
tctcaaatgagggatgaagtattcaagtcaaacttggtctgtgcatttatcgttcttcta
ttcatcacggcaatccaaagtttgcttccttcttcaagggtgatgccgttggccatccag
ttttccgttctgattatgctgcactcggctctggtcctcatcaccacagcagaggattat
aagtgcttgcccctcgtccttcggaaaacttgctgttggattaatgagacctatttggca
cggaatgtcatcatctttgcatccatcttgattaatttcctgggtgccatcctaaatatc
ctgtggtgtgattttgacaagtcgatacccttgaagaacctgactttcaattcctcagct
gtgtttacagatatctgctcctacccagagtatttcgtcttcacgggtgtgttggccatg
gtgacctgtgcggtattcctgcgacttaactccgtcctgaagctagccgtgctactgatt
atgatcgccatctatgccctactgaccgaaaccatctatgcaggcctctttctgcgttat
gacaacctgaaccacagtggagaagatttcctggggaccaaggaggcatcgctcctgcta
atggccatgttcctccttgctgtgttctaccatggacagcagctggagtacaccgcccgc
ctggacttcctgtggcgagtgcaggccaaggaggagatcaacgagatgaaggagctgagg
gaacacaacgagaacatgctccggaacatcctgcccagccacgtggcccgccacttcctg
gagaaagaccgggacaacgaggagctgtattctcagtcctatgatgctgttggggtgatg
ttcgcctccattccagggtttgccgacttttactcccagactgaaatgaacaaccaagga
gtggaatgcctgcgcttgctgaatgagatcattgctgacttcgatgaattgctcagcgag
gaccggtttcaagacattgaaaaaatcaagaccattggcagcacctacatggcagtgtca
ggcctgtcacctgaaaaacagcaatgtgaagacaagtgggatcatctgtgtgccctggcc
gacttctctctcgccctgtctgaaagcatacaggagatcaacaagcattcgttcaacaac
ttcgagctgcggatcggcatcagccatggctcagtggtagctggcgttattggcgctaag
aaaccccagtatgacatttggggcaaaaccgtgaacctggccagccgaatggatagcaca
ggggtcagcggcaggatccaagtcccagaggagacctatctcatcctgaaagaccagggc
tttgccttcgactaccgaggggagatctatgtgaagggcatcagtgaacaggaaggaaaa
atcaaaacatactttctcctgggaagagtccagcccaacccattcatcctgcccccaaga
agactgcccgggcaatactccttggccgcggtcgtcctcgggctcgtgcagtccctcaac
aggcaaaggcagaagcagctcctcaacgagaataacaacacggggatcatcaaggcccat
tacaaccggcggactttgttaactcccagtgggcccgagcccggagcccaagccgaaggc
accgacaaatccgatttgccataa

KEGG   Loxodonta africana (African savanna elephant): 100663448
Entry
100663448         CDS       T04351                                 

Gene name
ADCY9
Definition
(RefSeq) LOW QUALITY PROTEIN: adenylate cyclase type 9
  KO
K08049  adenylate cyclase 9 [EC:4.6.1.1]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav00230  Purine metabolism
lav01100  Metabolic pathways
lav01522  Endocrine resistance
lav04015  Rap1 signaling pathway
lav04020  Calcium signaling pathway
lav04022  cGMP-PKG signaling pathway
lav04024  cAMP signaling pathway
lav04062  Chemokine signaling pathway
lav04072  Phospholipase D signaling pathway
lav04114  Oocyte meiosis
lav04211  Longevity regulating pathway
lav04213  Longevity regulating pathway - multiple species
lav04261  Adrenergic signaling in cardiomyocytes
lav04270  Vascular smooth muscle contraction
lav04371  Apelin signaling pathway
lav04540  Gap junction
lav04611  Platelet activation
lav04713  Circadian entrainment
lav04714  Thermogenesis
lav04723  Retrograde endocannabinoid signaling
lav04724  Glutamatergic synapse
lav04725  Cholinergic synapse
lav04727  GABAergic synapse
lav04750  Inflammatory mediator regulation of TRP channels
lav04911  Insulin secretion
lav04912  GnRH signaling pathway
lav04913  Ovarian steroidogenesis
lav04914  Progesterone-mediated oocyte maturation
lav04915  Estrogen signaling pathway
lav04916  Melanogenesis
lav04918  Thyroid hormone synthesis
lav04921  Oxytocin signaling pathway
lav04923  Regulation of lipolysis in adipocytes
lav04925  Aldosterone synthesis and secretion
lav04926  Relaxin signaling pathway
lav04927  Cortisol synthesis and secretion
lav04928  Parathyroid hormone synthesis, secretion and action
lav04934  Cushing syndrome
lav04935  Growth hormone synthesis, secretion and action
lav04961  Endocrine and other factor-regulated calcium reabsorption
lav04962  Vasopressin-regulated water reabsorption
lav04970  Salivary secretion
lav04971  Gastric acid secretion
lav04972  Pancreatic secretion
lav04976  Bile secretion
lav05032  Morphine addiction
lav05163  Human cytomegalovirus infection
lav05166  Human T-cell leukemia virus 1 infection
lav05200  Pathways in cancer
lav05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:lav00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    100663448 (ADCY9)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100663448 (ADCY9)
   04371 Apelin signaling pathway
    100663448 (ADCY9)
   04020 Calcium signaling pathway
    100663448 (ADCY9)
   04072 Phospholipase D signaling pathway
    100663448 (ADCY9)
   04024 cAMP signaling pathway
    100663448 (ADCY9)
   04022 cGMP-PKG signaling pathway
    100663448 (ADCY9)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100663448 (ADCY9)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    100663448 (ADCY9)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100663448 (ADCY9)
   04062 Chemokine signaling pathway
    100663448 (ADCY9)
  09152 Endocrine system
   04911 Insulin secretion
    100663448 (ADCY9)
   04923 Regulation of lipolysis in adipocytes
    100663448 (ADCY9)
   04912 GnRH signaling pathway
    100663448 (ADCY9)
   04913 Ovarian steroidogenesis
    100663448 (ADCY9)
   04915 Estrogen signaling pathway
    100663448 (ADCY9)
   04914 Progesterone-mediated oocyte maturation
    100663448 (ADCY9)
   04921 Oxytocin signaling pathway
    100663448 (ADCY9)
   04926 Relaxin signaling pathway
    100663448 (ADCY9)
   04935 Growth hormone synthesis, secretion and action
    100663448 (ADCY9)
   04918 Thyroid hormone synthesis
    100663448 (ADCY9)
   04928 Parathyroid hormone synthesis, secretion and action
    100663448 (ADCY9)
   04916 Melanogenesis
    100663448 (ADCY9)
   04925 Aldosterone synthesis and secretion
    100663448 (ADCY9)
   04927 Cortisol synthesis and secretion
    100663448 (ADCY9)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100663448 (ADCY9)
   04270 Vascular smooth muscle contraction
    100663448 (ADCY9)
  09154 Digestive system
   04970 Salivary secretion
    100663448 (ADCY9)
   04971 Gastric acid secretion
    100663448 (ADCY9)
   04972 Pancreatic secretion
    100663448 (ADCY9)
   04976 Bile secretion
    100663448 (ADCY9)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    100663448 (ADCY9)
   04961 Endocrine and other factor-regulated calcium reabsorption
    100663448 (ADCY9)
  09156 Nervous system
   04724 Glutamatergic synapse
    100663448 (ADCY9)
   04727 GABAergic synapse
    100663448 (ADCY9)
   04725 Cholinergic synapse
    100663448 (ADCY9)
   04723 Retrograde endocannabinoid signaling
    100663448 (ADCY9)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100663448 (ADCY9)
  09149 Aging
   04211 Longevity regulating pathway
    100663448 (ADCY9)
   04213 Longevity regulating pathway - multiple species
    100663448 (ADCY9)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100663448 (ADCY9)
   04714 Thermogenesis
    100663448 (ADCY9)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100663448 (ADCY9)
  09165 Substance dependence
   05032 Morphine addiction
    100663448 (ADCY9)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    100663448 (ADCY9)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100663448 (ADCY9)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100663448 (ADCY9)
   05163 Human cytomegalovirus infection
    100663448 (ADCY9)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100663448 (ADCY9)
Enzymes [BR:lav01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     100663448 (ADCY9)
SSDB
Motif
Pfam: Guanylate_cyc DUF1053 AC_N
Other DBs
NCBI-GeneID: 100663448
NCBI-ProteinID: XP_003417791
LinkDB
Position
Unknown
AA seq 1344 aa
MASPPHQQLLHHHSTEVSCDSSGDSNSVRVKINPKQLSSGSHPKHCKYSISSSCSSSGDS
GGAPRRVGVGGRLRRQKKLPQLFERASSRWWDPKFDSVNLEEACMERCFPQTRRRFRYAL
FYIGFRLLAPGVSTFAGHMQSRLGVLVGPALIFFFTFSFTFTRLYARHYVCTALVLTLLV
FILTLALQFQVLTPLSGRADSSNHTPTVSPHSTCLSQVGSFSMCIEVLLLLYTVMHLPLY
LSLFLGVAYSILFETFGHHFRDADCFPPVWGALHWELLSRALLHLCIHAIGVHLLIMSQV
RSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDDDSENSVKRHPTS
SPKNKKKKFSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLSDLSW
SLQPLVXETQVXEISTLGDCYYCVAGCLEARGNHAYCCIEMGLADQAIQQFCQEKKNGEM
GCRVHGHVLCGLWGCGVKFNWGNDVNWANLMEQLGVAGKVHISESTAKYLDDRYEMEDGK
VFERLGQSVVADQLKGLKTYLISGQRAKESHCSCSEALLSGLKVIGGSQGSSGPRLQGTA
SPGSVSDLAQTVKTFDNLKTCLSCGITFAPKSEAGAEGGAVQNGCQDEHKNSSKASGGPN
SKAQNGLLSPPPEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNIREKTDAHFV
DVIKEDSLMKDYFFKPPINQFSLNFLDQELERTYRTSYQEEVIKNSPVKTFASATFSSLL
DVFLSTTVFLVLSVTCFLKYRATALSPPPAALAIFGVALVLEVLSLVVSVRMVFFLEDVM
LCTKRLLEWIAGWLPRHFIGAILVSLPALAVYSHVTSEFETNIHFTTFVCSAILIAVVQY
CNFCQLSSWMRSSLATIVGAGPLLLLYISLCPDSSIIIAHLDAVQNFSSQGSPCSGSLPH
DSRKPASLIGQEVVLVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKIQSMRDQAD
WLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKECYRVLNELI
GDFDELLSKPDYSSIEKIKTIGATYMAASGLNTAQCQDSSHPQEHLQILFEFAKEMMRVV
DDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECRIQVS
EESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCIDNGIVPQHQLSISPDIRVQVDGS
IGRSPTDEIANLVPSVQNLDRASLSSDSSTQAKDVHLSSKRPWREPVRAEESCRFSKAME
KSDCEEVGLEEANELTKLNVSGSL
NT seq 4035 nt   +upstreamnt  +downstreamnt
atggcttccccgccccaccagcagctgctgcatcaccacagcaccgaggtgagctgcgac
tccagcggagacagcaacagcgtgcgggtcaaaatcaaccccaagcagctctcatctgga
agccaccccaagcactgcaagtacagcatctcctccagctgcagcagttcgggggactcc
gggggcgcgccccggagggtgggcgtcgggggccgcctgcgccggcagaagaagctgccg
cagctgttcgagagagcctccagccgctggtgggaccccaaattcgactcggtgaacctg
gaggaggcgtgcatggagcgctgcttcccgcaaacccggcgccgcttccgctatgcgctc
ttctacatcggctttcgcctgcttgctcctggagtgtctacttttgcgggccacatgcaa
tccagactgggggtcttggtaggccctgcccttattttcttttttaccttctcttttacc
ttcaccagactgtacgcccggcactacgtgtgcaccgcgctggtgctcactctcttggtg
ttcatcctcactctggccttgcagtttcaggttttgacgcctctctcaggacgcgctgac
agctccaatcacacacccacagtcagcccccactccacctgcttgtctcaagtggggagc
ttctccatgtgcatcgaagtgctccttttgctgtacactgtcatgcacttacctttgtat
ttgagcctgttcctgggagtggcctattctattctctttgagacctttggccaccatttc
cgagatgcagactgcttccctccggtgtggggagccctgcactgggagctgctgagcagg
gccttgctccacctctgcattcacgccatcggggtccacctgctcatcatgtcccaggtg
aggtccaggagcactttcctcaaggtggggcagtccattatgcacgggaaggatctggaa
gtagaaaaagccctcaaagagagaatgatccactctgtgatgcccagaatcatcgctgat
gacttaatgaaacagggtgatgatgacagtgagaattctgtcaaaaggcaccccacctcg
agccccaagaacaagaagaagaaattttctatacagaaagcgcctatagccttccgccct
tttaaaatgcagcagatcgaagaggtcagcattttgtttgcagacattgtgggcttcacc
aagatgagtgccaacaagtccgcgcatgccctggtagggcttctcagcgacttgtcgtgg
tctctccaaccgcttgtgtgagagacacaagtgtgagagatcagcacgttgggtgactgt
tactattgtgtggcagggtgtctcgaagcccggggaaaccatgcctactgctgcatcgaa
atgggcttggctgatcaagccatccaacagttctgccaggaaaaaaagaatggtgaaatg
ggttgtcgggttcacgggcacgttttgtgtgggctctggggttgcggagttaaattcaac
tggggtaatgatgtgaattgggccaacctcatggagcagctgggagtggctggcaaggtc
cacatttccgagtccactgcaaaatacttagatgatcggtacgaaatggaagacgggaag
gtgtttgagcgcctgggccagagtgtggtggctgaccagttgaaaggtctgaagacatac
ctgatatcgggtcagagagcgaaggagtctcattgcagctgttcagaggccttgctttct
ggcctcaaggtcattggcggctcccaggggtcttcaggccctaggttacaggggacagca
tcaccagggagtgtcagtgacttggcacagactgtcaaaacctttgataaccttaagacc
tgcctttcatgtggaattacgtttgctccaaaatctgaagctggtgcagaaggaggagca
gtccaaaatggctgtcaagacgagcataaaaacagcagcaaggcttctggaggacctaat
tccaaagcccagaatggacttctgagccctccaccagaggagaagcttaccaacagtcag
acctccctgtgtgagatcctacaggaaaagggaaggtgggcaggggtgagcttggaccaa
tctgccctccttccgttgagattcaagaatatccgggagaaaacagatgcccattttgtt
gatgttattaaagaagatagcctgatgaaagattatttttttaaaccacccattaatcag
ttcagcttgaacttcttggaccaggagctagagcgaacctacaggaccagctaccaagaa
gaggtcataaagaattctcccgtgaagacttttgccagtgccaccttcagttcccttctg
gatgtgtttctgtcaacaactgtgtttctagtcctctccgtcacctgcttcctgaagtac
agggccaccgccttgtccccaccgcctgctgccctggccatctttggtgtggccctggtg
ctggaggtgctctccctcgttgtctctgtcaggatggtgttcttcctggaagatgtcatg
ttgtgtaccaagcgcctgctggagtggatcgccggctggcttcctcgtcacttcatcgga
gcaatcctggtgtcactccctgcccttgccgtctattcccatgtcacctctgagtttgag
acaaacattcattttaccacgttcgtgtgctcagccatcctcatcgctgtcgtgcagtac
tgcaacttctgccagctcagctcctggatgcggtcctcgctggccaccattgttggggct
gggcccctgctcctgctttatatctccctgtgtccagacagttccataataattgcacac
cttgatgcagtacagaatttcagttcccaggggagtccctgcagtggctcactgccacat
gacagcaggaagccagccagtctgattggccaggaggtggttctcgtcttctttcttctg
ctcctcctggtctggttcctgaaccgagagttcgaagtcagctaccgcttacactaccat
ggcgacgtggaagcggaccttcaccgcaccaagatccagagcatgcgagaccaggctgac
tggctgctgagaaacatcattccttaccatgtggccgagcagctcaaggtgtctcagacc
tattccaagaaccatgacagtggaggggtcatcttcgccagcatcgtcaacttcagcgaa
ttctacgaggagaactacgaggggggcaaggagtgctaccgggtcctcaacgaactcatt
ggggactttgacgagctcctaagcaagccggactacagcagcattgagaagatcaagacc
attggggcgacctacatggctgcctcggggctgaacacggctcagtgccaggatagcagc
cacccgcaggaacacctgcagatcctgttcgagtttgccaaggagatgatgcgtgtggtg
gatgacttcaataacaacatgttgtggttcaacttcaaactccgtgtcggcttcaaccat
gggcccctgactgcaggggtcatcggcaccacaaagctgctgtacgatatctggggggac
acggtcaacattgccagcaggatggataccactggggtagaatgccgcattcaggtgagt
gaagagagctaccgggtcctgagcaagatgggctatgactttgactacagagggacagtg
aatgtcaaggggaaaggtcaaatgaagacctacctctaccccaagtgtatagacaacggg
atcgtgcctcaacaccagctgtccatctccccggacatccgggtccaggtggacgggagc
atcgggcggtcacccactgatgagatcgccaacctggtgccttctgtacagaatttggac
agggcgtctctgagttccgatagcagcacacaggccaaggatgtccacctgtcttctaag
aggccctggagggagcctgtcagagcagaagagagttgccgcttcagcaaagccatggag
aaaagcgactgtgaggaagtagggctggaggaagccaatgagctcaccaagctcaatgtc
tccgggagcttgtga

KEGG   Loxodonta africana (African savanna elephant): 100670244
Entry
100670244         CDS       T04351                                 

Gene name
ADCY5
Definition
(RefSeq) LOW QUALITY PROTEIN: adenylate cyclase type 5
  KO
K08045  adenylate cyclase 5 [EC:4.6.1.1]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav00230  Purine metabolism
lav01100  Metabolic pathways
lav01522  Endocrine resistance
lav04015  Rap1 signaling pathway
lav04022  cGMP-PKG signaling pathway
lav04024  cAMP signaling pathway
lav04062  Chemokine signaling pathway
lav04072  Phospholipase D signaling pathway
lav04114  Oocyte meiosis
lav04211  Longevity regulating pathway
lav04213  Longevity regulating pathway - multiple species
lav04261  Adrenergic signaling in cardiomyocytes
lav04270  Vascular smooth muscle contraction
lav04371  Apelin signaling pathway
lav04540  Gap junction
lav04611  Platelet activation
lav04713  Circadian entrainment
lav04714  Thermogenesis
lav04723  Retrograde endocannabinoid signaling
lav04724  Glutamatergic synapse
lav04725  Cholinergic synapse
lav04726  Serotonergic synapse
lav04727  GABAergic synapse
lav04728  Dopaminergic synapse
lav04750  Inflammatory mediator regulation of TRP channels
lav04911  Insulin secretion
lav04912  GnRH signaling pathway
lav04913  Ovarian steroidogenesis
lav04914  Progesterone-mediated oocyte maturation
lav04915  Estrogen signaling pathway
lav04916  Melanogenesis
lav04918  Thyroid hormone synthesis
lav04921  Oxytocin signaling pathway
lav04923  Regulation of lipolysis in adipocytes
lav04924  Renin secretion
lav04925  Aldosterone synthesis and secretion
lav04926  Relaxin signaling pathway
lav04927  Cortisol synthesis and secretion
lav04928  Parathyroid hormone synthesis, secretion and action
lav04934  Cushing syndrome
lav04935  Growth hormone synthesis, secretion and action
lav04970  Salivary secretion
lav04971  Gastric acid secretion
lav04972  Pancreatic secretion
lav04976  Bile secretion
lav05012  Parkinson disease
lav05030  Cocaine addiction
lav05031  Amphetamine addiction
lav05032  Morphine addiction
lav05034  Alcoholism
lav05163  Human cytomegalovirus infection
lav05166  Human T-cell leukemia virus 1 infection
lav05200  Pathways in cancer
lav05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:lav00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    100670244 (ADCY5)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100670244 (ADCY5)
   04371 Apelin signaling pathway
    100670244 (ADCY5)
   04072 Phospholipase D signaling pathway
    100670244 (ADCY5)
   04024 cAMP signaling pathway
    100670244 (ADCY5)
   04022 cGMP-PKG signaling pathway
    100670244 (ADCY5)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100670244 (ADCY5)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    100670244 (ADCY5)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100670244 (ADCY5)
   04062 Chemokine signaling pathway
    100670244 (ADCY5)
  09152 Endocrine system
   04911 Insulin secretion
    100670244 (ADCY5)
   04923 Regulation of lipolysis in adipocytes
    100670244 (ADCY5)
   04912 GnRH signaling pathway
    100670244 (ADCY5)
   04913 Ovarian steroidogenesis
    100670244 (ADCY5)
   04915 Estrogen signaling pathway
    100670244 (ADCY5)
   04914 Progesterone-mediated oocyte maturation
    100670244 (ADCY5)
   04921 Oxytocin signaling pathway
    100670244 (ADCY5)
   04926 Relaxin signaling pathway
    100670244 (ADCY5)
   04935 Growth hormone synthesis, secretion and action
    100670244 (ADCY5)
   04918 Thyroid hormone synthesis
    100670244 (ADCY5)
   04928 Parathyroid hormone synthesis, secretion and action
    100670244 (ADCY5)
   04916 Melanogenesis
    100670244 (ADCY5)
   04924 Renin secretion
    100670244 (ADCY5)
   04925 Aldosterone synthesis and secretion
    100670244 (ADCY5)
   04927 Cortisol synthesis and secretion
    100670244 (ADCY5)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100670244 (ADCY5)
   04270 Vascular smooth muscle contraction
    100670244 (ADCY5)
  09154 Digestive system
   04970 Salivary secretion
    100670244 (ADCY5)
   04971 Gastric acid secretion
    100670244 (ADCY5)
   04972 Pancreatic secretion
    100670244 (ADCY5)
   04976 Bile secretion
    100670244 (ADCY5)
  09156 Nervous system
   04724 Glutamatergic synapse
    100670244 (ADCY5)
   04727 GABAergic synapse
    100670244 (ADCY5)
   04725 Cholinergic synapse
    100670244 (ADCY5)
   04728 Dopaminergic synapse
    100670244 (ADCY5)
   04726 Serotonergic synapse
    100670244 (ADCY5)
   04723 Retrograde endocannabinoid signaling
    100670244 (ADCY5)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100670244 (ADCY5)
  09149 Aging
   04211 Longevity regulating pathway
    100670244 (ADCY5)
   04213 Longevity regulating pathway - multiple species
    100670244 (ADCY5)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100670244 (ADCY5)
   04714 Thermogenesis
    100670244 (ADCY5)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100670244 (ADCY5)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    100670244 (ADCY5)
  09165 Substance dependence
   05030 Cocaine addiction
    100670244 (ADCY5)
   05031 Amphetamine addiction
    100670244 (ADCY5)
   05032 Morphine addiction
    100670244 (ADCY5)
   05034 Alcoholism
    100670244 (ADCY5)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    100670244 (ADCY5)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100670244 (ADCY5)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100670244 (ADCY5)
   05163 Human cytomegalovirus infection
    100670244 (ADCY5)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100670244 (ADCY5)
Enzymes [BR:lav01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     100670244 (ADCY5)
SSDB
Motif
Pfam: AC_N Guanylate_cyc DUF1053 HNOBA TBK1_ULD
Other DBs
NCBI-GeneID: 100670244
NCBI-ProteinID: XP_003413007
LinkDB
Position
Unknown
AA seq 1261 aa
MSRTKSVSPPGYAAQTAAAPAPRGGPEHRSAWGEADPRANGYPHPPGGSARGSTKKPGGA
VTPQQRQRLASRWRGDDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQRR
GAAGGGSTRAPSAGGGGGSAAAAAAAGGTEVRPRSVELGLEERRGKGRATDDLEAGAVED
GEGSGDGGSSAGSDAGPGAKLSLGACCLALLQVNRSKKFPSDQLKRLYQRYFLRPERLNQ
SSLTMLMAVLVLVCLVMPFHAARPPLQLPYLAVLATAVGVIVIMAVLCNRAAFHQDHMGL
ACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVVSGVLLSAL
HLAIALRANSQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLH
SQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTS
LASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEM
GMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGK
AGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMN
RQRANSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEFL
GRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQI
TIVPHSVFMLSFYLTCFLLLILVVFVSVIYSCVKLFPAPLQTLSRKIVRSKMNSTLVGVF
TITLVFLSAFVNMFMCNSKDLFSCLGDEHNVSVSQINACHVVESAFNYSLGEEQGFCGSP
WPNCNFPEYFTYSVVLSMLACSVFLQMSCIGKLVLMLAIELIYVLVVEVPGVTLFDNADL
LVTANAIDLNNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKL
QATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANF
SEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTY
DKVGRTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWG
NTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPL
S
NT seq 3786 nt   +upstreamnt  +downstreamnt
atgtcccgcactaaaagcgtcagccccccgggctacgcggcgcagacagcggcggcgccc
gcgccccggggaggccccgaacaccgctcggcgtggggagaggccgatccccgtgccaat
ggctaccctcacccccctgggggctcggcccgcggctccaccaagaagcccgggggggcc
gtgaccccccagcagcggcagcgcctggccagccgctggcgcggcgacgacgacgacgat
cctccgctgagcggcgacgaccccctggccgggggcttcggcttcagcttccgctccaag
tccgcctggcaggagcgtggcggcgacgactgcggtcggggcagccgccggcagcggcgg
ggcgcggcaggcgggggcagcacccgggcgccctctgcgggtggcggcggcggctccgcg
gcggcggcggccgcagccggcggcaccgaggtgcgaccccgctcggtggagctgggcctg
gaggagcggcggggcaagggccgcgccaccgacgacctggaggccggcgccgtcgaggac
ggcgaggggtccggggatggcggcagctccgcgggctcggacgcgggtcccggcgcgaaa
ctgtcgctgggcgcctgctgcctggccctgctgcaggtaaaccgctccaagaagttccca
tcggaccagctgaagcggctgtaccagcgctactttcttcgccctgaacgcctgaaccag
agcagcctcaccatgctcatggcagtgctggtgctcgtgtgtctggtcatgcctttccac
gcggcgcggcccccgctccagctgccctacctggccgtgctggccaccgccgtgggcgtc
atcgtcatcatggccgtgctctgcaaccgcgccgctttccaccaagaccatatgggcctc
gcctgctacgcgctcatcgccgtcgtgctggcggtccaggtggtgggcctgctgctgccc
cagccgcgcagcgcctcggagggcatctggtggaccgtgttcttcatctacaccatctat
acgctgctgccggtgcgcatgcgggcggcggtggtcagcggggtgctcctgtctgccctt
cacctggccatcgccctgcgtgccaactctcaggaccagttcctgctcaagcagctggtc
tccaatgtcctcattttctcctgcaccaacatcgtgggggtctgcacccactacccggcc
gaggtctcccagagacaggcctttcaggagacccgggagtgcatccaggcgcggctccac
tcgcagcgggagaaccagcagcaggagcggctcctgctgtctgtccttccccggcatgtt
gccatggagatgaaagcagacatcaacgccaagcaagaggatatgatgtttcacaagatt
tacatccagaaacatgacaacgtgagcatcctgtttgctgatatcgagggcttcaccagc
ctggcatcccagtgcactgcacaggagctggtcatgaccctcaacgagctctttgcccgc
ttcgacaagctggctgcggagaatcactgtttacgtattaagatcctgggggactgttac
tactgcgtctcggggctgcctgaagcgagggccgaccatgcccactgctgcgtggagatg
ggcatggatatgattgaggccatctcgttggtccgggaggtgactggggtgaacgtgaac
atgcgcgtgggaattcacagcgggcgagtacactgcggtgtccttggtctcaggaagtgg
cagttcgacgtctggtctaacgacgtcacgctggccaaccacatggaggctggaggcaag
gcgggacgcatacacatcaccaaggccacactcaactacctgaatggagactatgaggtg
gagccgggctgtgggggcgagcgcaacgcctacctcaaggagcacagtattgagaccttc
ctcatcctgcgctgcacccagaagcggaaagaagagaaggccatgatcgccaagatgaat
cgccagagagccaactccattgggcataacccgccacactggggcgctgagcgccccttc
tacaaccacctgggtggcaaccaggtctccaaggagatgaagcggatgggctttgaagac
cccaaggacaagaacgcccaggaaagtgcgaaccccgaggacgaagtggatgagtttctg
gggcgggccatcgacgccaggagcatcgacaggctgcgctctgagcatgtccgcaaattc
ctcttgaccttcagggagcctgacttagagaagaagtattccaagcaggtggacgaccgg
tttggtgcctacgtggcatgtgcctctcttgtcttcctcttcatttgcttcgtccagatc
accatcgtgccccactccgtgttcatgttgagtttctacctgacctgcttcctgctgctg
atcttggtggtatttgtgtcggtgatctactcctgcgtgaagctcttcccagccccactg
cagaccctctccaggaagattgtgcggtccaagatgaacagcaccctggtcggggtgttc
accatcaccctggtgttcctgtcagcttttgtcaacatgttcatgtgcaactccaaggac
ctgttcagctgcctgggcgacgagcacaacgtcagtgtgagccagatcaacgcgtgccac
gtggtggagtcagccttcaactacagcctaggcgaggagcagggcttctgcggcagcccc
tggcccaactgcaacttccccgagtacttcacctacagcgtggtgctcagcatgctggcc
tgctccgtgttcctgcagatgagctgcatcgggaagctggtgctcatgctcgccatcgag
ctcatctacgtgctcgtcgtcgaggtgcctggcgtcacgctgtttgacaatgcggacctg
ctggtcaccgccaacgccatagatctgaacaacaacgggacctcccagtgccctgagcac
gcgaccaaggtggcgctgaaggtggtgacccccatcatcatctcagtcttcgtgctggcc
ctgtacctgcacgctcagcaggtggagtccactgctcgcctggacttcctctggaaactg
caggctacagaggagaaggaggagatggaggagctacaggcatataaccggcggctgctg
cacaacatcctgcccaaggacgtggctgcccacttcctggcccgcgagcgccggaacgac
gagctctactaccagtcatgtgagtgcgtggccgtcatgttcgcctccatcgccaacttc
tccgagttctacgtggagctggaggccaacaacgagggagttgagtgcctgcggctgctc
aacgagatcattgcagacttcgacgagatcatcagcgaggatcggttcaggcagctggaa
aagatcaagaccatcggcagtacctacatggctgcctcgggcctcaatgattccacctat
gacaaggtgggcaggacccacatcaaggctctggctgacttcgccatgaagctgatggac
caaatgaagtacatcaacgagcactccttcaacaacttccagatgaagatcgggctcaac
atcggccctgtggtggctggggtgatcggggctcgcaagcctcagtacgacatctggggc
aatacggtgaatgtggccagccgcatggacagcaccggtgtgcctgaccgcatccaggtc
accacagacatgtaccaggtgctggctgccaacacataccagctggagtgccggggtgtg
gtcaaggtcaagggcaaaggcgagatgatgacctacttcctcaatggagggcccccgctc
agttag

KEGG   Loxodonta africana (African savanna elephant): 100671072
Entry
100671072         CDS       T04351                                 

Gene name
ADCY1
Definition
(RefSeq) adenylate cyclase type 1
  KO
K08041  adenylate cyclase 1 [EC:4.6.1.1]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav00230  Purine metabolism
lav01100  Metabolic pathways
lav01522  Endocrine resistance
lav04015  Rap1 signaling pathway
lav04020  Calcium signaling pathway
lav04022  cGMP-PKG signaling pathway
lav04024  cAMP signaling pathway
lav04062  Chemokine signaling pathway
lav04072  Phospholipase D signaling pathway
lav04114  Oocyte meiosis
lav04211  Longevity regulating pathway
lav04213  Longevity regulating pathway - multiple species
lav04261  Adrenergic signaling in cardiomyocytes
lav04270  Vascular smooth muscle contraction
lav04371  Apelin signaling pathway
lav04540  Gap junction
lav04611  Platelet activation
lav04713  Circadian entrainment
lav04714  Thermogenesis
lav04720  Long-term potentiation
lav04723  Retrograde endocannabinoid signaling
lav04724  Glutamatergic synapse
lav04725  Cholinergic synapse
lav04727  GABAergic synapse
lav04750  Inflammatory mediator regulation of TRP channels
lav04911  Insulin secretion
lav04912  GnRH signaling pathway
lav04913  Ovarian steroidogenesis
lav04914  Progesterone-mediated oocyte maturation
lav04915  Estrogen signaling pathway
lav04916  Melanogenesis
lav04918  Thyroid hormone synthesis
lav04921  Oxytocin signaling pathway
lav04923  Regulation of lipolysis in adipocytes
lav04925  Aldosterone synthesis and secretion
lav04926  Relaxin signaling pathway
lav04927  Cortisol synthesis and secretion
lav04928  Parathyroid hormone synthesis, secretion and action
lav04934  Cushing syndrome
lav04935  Growth hormone synthesis, secretion and action
lav04970  Salivary secretion
lav04971  Gastric acid secretion
lav04972  Pancreatic secretion
lav04976  Bile secretion
lav05032  Morphine addiction
lav05142  Chagas disease
lav05146  Amoebiasis
lav05163  Human cytomegalovirus infection
lav05166  Human T-cell leukemia virus 1 infection
lav05200  Pathways in cancer
lav05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:lav00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    100671072 (ADCY1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100671072 (ADCY1)
   04371 Apelin signaling pathway
    100671072 (ADCY1)
   04020 Calcium signaling pathway
    100671072 (ADCY1)
   04072 Phospholipase D signaling pathway
    100671072 (ADCY1)
   04024 cAMP signaling pathway
    100671072 (ADCY1)
   04022 cGMP-PKG signaling pathway
    100671072 (ADCY1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100671072 (ADCY1)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    100671072 (ADCY1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100671072 (ADCY1)
   04062 Chemokine signaling pathway
    100671072 (ADCY1)
  09152 Endocrine system
   04911 Insulin secretion
    100671072 (ADCY1)
   04923 Regulation of lipolysis in adipocytes
    100671072 (ADCY1)
   04912 GnRH signaling pathway
    100671072 (ADCY1)
   04913 Ovarian steroidogenesis
    100671072 (ADCY1)
   04915 Estrogen signaling pathway
    100671072 (ADCY1)
   04914 Progesterone-mediated oocyte maturation
    100671072 (ADCY1)
   04921 Oxytocin signaling pathway
    100671072 (ADCY1)
   04926 Relaxin signaling pathway
    100671072 (ADCY1)
   04935 Growth hormone synthesis, secretion and action
    100671072 (ADCY1)
   04918 Thyroid hormone synthesis
    100671072 (ADCY1)
   04928 Parathyroid hormone synthesis, secretion and action
    100671072 (ADCY1)
   04916 Melanogenesis
    100671072 (ADCY1)
   04925 Aldosterone synthesis and secretion
    100671072 (ADCY1)
   04927 Cortisol synthesis and secretion
    100671072 (ADCY1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100671072 (ADCY1)
   04270 Vascular smooth muscle contraction
    100671072 (ADCY1)
  09154 Digestive system
   04970 Salivary secretion
    100671072 (ADCY1)
   04971 Gastric acid secretion
    100671072 (ADCY1)
   04972 Pancreatic secretion
    100671072 (ADCY1)
   04976 Bile secretion
    100671072 (ADCY1)
  09156 Nervous system
   04724 Glutamatergic synapse
    100671072 (ADCY1)
   04727 GABAergic synapse
    100671072 (ADCY1)
   04725 Cholinergic synapse
    100671072 (ADCY1)
   04720 Long-term potentiation
    100671072 (ADCY1)
   04723 Retrograde endocannabinoid signaling
    100671072 (ADCY1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100671072 (ADCY1)
  09149 Aging
   04211 Longevity regulating pathway
    100671072 (ADCY1)
   04213 Longevity regulating pathway - multiple species
    100671072 (ADCY1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100671072 (ADCY1)
   04714 Thermogenesis
    100671072 (ADCY1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100671072 (ADCY1)
  09165 Substance dependence
   05032 Morphine addiction
    100671072 (ADCY1)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    100671072 (ADCY1)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100671072 (ADCY1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100671072 (ADCY1)
   05163 Human cytomegalovirus infection
    100671072 (ADCY1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100671072 (ADCY1)
   05142 Chagas disease
    100671072 (ADCY1)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100671072 (ADCY1)
Enzymes [BR:lav01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     100671072 (ADCY1)
SSDB
Motif
Pfam: Guanylate_cyc AC_N DUF1053 HNOBA
Other DBs
NCBI-GeneID: 100671072
NCBI-ProteinID: XP_023399960
LinkDB
Position
Unknown
AA seq 1011 aa
MQQISKLTLFFSLTFALLCCPFALGGSASAHAAGSAAAQQGVWQLLLVTFVSYALLPVPS
LLAIGFGLVVAASHLLVSATLVPAKRPCLWRTLGANALLFVSVNMYGAFVRILTERSQRK
AFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDN
VSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLT
QPKTDHAHCCVEMGLDMIDTITSVAEATEVNLNMRVGLHTGRVLCGVLGLRKWQYDVWSN
DVTLANVMEAAGLPGKVHITKTTLECLNGDYEVEPGYGHERNSFLKTHNIKTFFIVPSHR
RKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALRT
ASEKLRNRSSFSTNVVYTTPGTRVNRYISRLLEARQTELEMADLNFFTLRYKHVEREQKY
HKLQDEYFTSAVGLALILAALLGLVYLLIIPQNLVALVLLVFCICFLVACIMYLHITRVQ
CFPGCLTIQIRTTLCIFIVVLIYSVAQGCMVGCMPWAWRSSPNSSLMVLLPRGRSTALPT
SPCTSVPHALLCCLVGTLTLATFLRVPSWPKTLLLLVLTMLSVLMLGLSGPTGAAGGRAV
SLPSYEPILAILLFSCALGLHSRQVDLKLRLDYLWAMQAEEERDDMEKVKLDNKRILFNL
LPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEI
IADFDELMEKDFYKDLEKIKTIGSTYMAAVGLAPTAGAKAEKSITSHLSVLADFAIEMFD
VLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGKIQV
TEEVHRLLKGCSYQFMCRGKVSVKGKGEMLTYFLEGRIDGSGSQTRSLNMERKMCPYRKA
GLQTRLATSCPPVPSVAGFSVQAGLGAVQSTGLPSQPTLQYLPSRAAVKEA
NT seq 3036 nt   +upstreamnt  +downstreamnt
atgcagcagatcagcaagctcacgctgttcttcagccttaccttcgcgctgctctgctgt
ccctttgcgttgggcggttccgccagtgcccacgctgcggggtcggcggctgcccaacag
ggcgtctggcagctccttttggtcactttcgtgtcctatgccctgctgcccgtgcccagc
ctgctggctatcggctttgggcttgtggtggccgcatctcacttgctggtctccgccacc
ttggtccccgccaagcgcccatgtctctggaggacgcttggagccaacgccctgctcttc
gtcagtgtgaacatgtatggggccttcgtgcggatcctgaccgagcgctcccagaggaag
gctttcctgcaggcccgcaactgcatcgaggacaggctgaggctggaagatgagaatgag
aagcaggagcggctcctgatgagtctcctgccccgcaacgttgccatggagatgaaggag
gattttctgaaaccccctgagaggattttccataaaatttacatccagagacatgacaac
gtgagcattctgtttgcagacattgtgggcttcacggggctggcgtcccagtgcacagcc
caggagctggtgaaacttctgaatgagctcttcgggaagtttgatgagctagccacggag
aaccactgccggcggatcaagatcctgggggactgctattactgcgtgtcgggcctcacc
cagcccaagactgaccacgcccactgctgtgtggagatggggcttgacatgattgatacc
atcacatctgtggctgaggccactgaggtgaacctgaacatgcgtgtggggctgcacaca
ggccgggtgctctgtggggtgctgggcctgcgcaagtggcagtacgatgtatggtccaat
gatgtgaccctagccaacgtcatggaagccgccggcctgccagggaaggttcatatcaca
aagacgaccctagagtgcttgaatggggactacgaggtagaaccgggttatggacatgag
aggaacagtttcttgaaaactcataatatcaaaacattttttattgtgccatcccatcgg
cgaaagatatttccaggactgattctctcagatataaaaccagccaaaaggatgaagttc
aaaactgtctgctacctgctggtgcagctcatgcattgccggaagatgttcaaggccgag
atccccttctccaacgtcatgacgtgtgaggacgatgacaagcggagggcgttgagaaca
gcctcagaaaaactcagaaaccggtcatctttctccaccaatgttgtctacaccacgcct
ggcactcgtgtcaacagatacatcagccgcctcttggaggcccggcaaacagagttggag
atggcagacttgaacttctttaccctgaggtacaagcacgttgaacgagaacaaaagtac
cacaagcttcaagacgagtacttcaccagtgctgttggtcttgcactcattctagctgcc
ttacttggccttgtctaccttctcataatcccacagaacctggtcgctttggtcctgctt
gtgttctgcatttgcttcttggtggcatgtatcatgtatctgcacatcacacgagtccag
tgttttccagggtgcctgacgattcagatccgtaccaccttgtgtatcttcatcgtggtc
ttaatctattcagtggcccaaggatgtatggtgggctgcatgccctgggcctggcgctcg
agccccaacagctccctgatggtcctcttgcccagaggccgcagcactgcgctgcccact
tcgccctgtacgtcggtgccccatgccctgctctgctgcctcgtgggcaccctcacactg
gccaccttcctgcgcgtcccctcctggcccaagacgctcctcctgctagtgctcaccatg
ctgtctgtcctcatgctggggctcagcgggcccacaggagcagctggcggccgtgctgtc
tccttgcccagctatgagcccatcttggccatcctgctcttctcctgcgcactgggcctg
cactccaggcaggtggacctcaagctgcggctggactacctctgggccatgcaggcagaa
gaggagcgtgatgacatggagaaggtcaaactggacaacaagaggatcctcttcaacctc
ttaccagcccatgtggcccagcacttcctcatgtcaaatcccagaaacatggacctctat
taccagtcatactcacaagtgggtgtcatgttcgcttccatccccaacttcaatgacttc
tacattgagctggatggcaacaacatgggggtggagtgtctgcgcctcctgaacgagatt
atcgccgactttgatgagctcatggagaaagacttttataaggacctagagaagataaag
accatcgggagcacatacatggcggctgtggggctggcacccacggcgggggccaaggct
gagaagtccatcacctcccaccttagtgtacttgcggactttgccatcgagatgtttgac
gtactggatgaaatcaactatcagtcatacaatgactttgtcctccgtgtgggcattaat
gtcggccccgtggtggctggggtgatcggagcccggaggcctcagtacgacatctggggc
aacacggtcaacgtggccagccgcatggacagcaccggggtccagggcaagattcaggtg
acagaggaagttcaccggctgctgaaagggtgcagctaccagttcatgtgcagaggaaaa
gtcagtgtcaagggcaaaggtgaaatgctgacatacttcctagagggaaggattgatgga
agtggctcccaaaccaggtctttaaacatggagcggaaaatgtgtccttacaggaaagcc
ggcctccagaccagactggccaccagctgccccccggtgcccagtgtggctggcttctca
gtccaagcggggctgggggctgtgcagagcacaggcctcccttcacagcccactctccag
tacctcccctccagagcagctgtgaaggaggcttag

KEGG   Loxodonta africana (African savanna elephant): 100673570
Entry
100673570         CDS       T04351                                 

Gene name
ADCY2
Definition
(RefSeq) LOW QUALITY PROTEIN: adenylate cyclase type 2
  KO
K08042  adenylate cyclase 2 [EC:4.6.1.1]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav00230  Purine metabolism
lav01100  Metabolic pathways
lav01522  Endocrine resistance
lav04015  Rap1 signaling pathway
lav04020  Calcium signaling pathway
lav04022  cGMP-PKG signaling pathway
lav04024  cAMP signaling pathway
lav04062  Chemokine signaling pathway
lav04072  Phospholipase D signaling pathway
lav04114  Oocyte meiosis
lav04211  Longevity regulating pathway
lav04213  Longevity regulating pathway - multiple species
lav04261  Adrenergic signaling in cardiomyocytes
lav04270  Vascular smooth muscle contraction
lav04371  Apelin signaling pathway
lav04540  Gap junction
lav04611  Platelet activation
lav04713  Circadian entrainment
lav04714  Thermogenesis
lav04723  Retrograde endocannabinoid signaling
lav04724  Glutamatergic synapse
lav04725  Cholinergic synapse
lav04727  GABAergic synapse
lav04750  Inflammatory mediator regulation of TRP channels
lav04911  Insulin secretion
lav04912  GnRH signaling pathway
lav04913  Ovarian steroidogenesis
lav04914  Progesterone-mediated oocyte maturation
lav04915  Estrogen signaling pathway
lav04916  Melanogenesis
lav04918  Thyroid hormone synthesis
lav04921  Oxytocin signaling pathway
lav04922  Glucagon signaling pathway
lav04923  Regulation of lipolysis in adipocytes
lav04925  Aldosterone synthesis and secretion
lav04926  Relaxin signaling pathway
lav04927  Cortisol synthesis and secretion
lav04928  Parathyroid hormone synthesis, secretion and action
lav04934  Cushing syndrome
lav04935  Growth hormone synthesis, secretion and action
lav04970  Salivary secretion
lav04971  Gastric acid secretion
lav04972  Pancreatic secretion
lav04976  Bile secretion
lav05032  Morphine addiction
lav05163  Human cytomegalovirus infection
lav05166  Human T-cell leukemia virus 1 infection
lav05200  Pathways in cancer
lav05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:lav00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    100673570 (ADCY2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100673570 (ADCY2)
   04371 Apelin signaling pathway
    100673570 (ADCY2)
   04020 Calcium signaling pathway
    100673570 (ADCY2)
   04072 Phospholipase D signaling pathway
    100673570 (ADCY2)
   04024 cAMP signaling pathway
    100673570 (ADCY2)
   04022 cGMP-PKG signaling pathway
    100673570 (ADCY2)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100673570 (ADCY2)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    100673570 (ADCY2)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100673570 (ADCY2)
   04062 Chemokine signaling pathway
    100673570 (ADCY2)
  09152 Endocrine system
   04911 Insulin secretion
    100673570 (ADCY2)
   04922 Glucagon signaling pathway
    100673570 (ADCY2)
   04923 Regulation of lipolysis in adipocytes
    100673570 (ADCY2)
   04912 GnRH signaling pathway
    100673570 (ADCY2)
   04913 Ovarian steroidogenesis
    100673570 (ADCY2)
   04915 Estrogen signaling pathway
    100673570 (ADCY2)
   04914 Progesterone-mediated oocyte maturation
    100673570 (ADCY2)
   04921 Oxytocin signaling pathway
    100673570 (ADCY2)
   04926 Relaxin signaling pathway
    100673570 (ADCY2)
   04935 Growth hormone synthesis, secretion and action
    100673570 (ADCY2)
   04918 Thyroid hormone synthesis
    100673570 (ADCY2)
   04928 Parathyroid hormone synthesis, secretion and action
    100673570 (ADCY2)
   04916 Melanogenesis
    100673570 (ADCY2)
   04925 Aldosterone synthesis and secretion
    100673570 (ADCY2)
   04927 Cortisol synthesis and secretion
    100673570 (ADCY2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100673570 (ADCY2)
   04270 Vascular smooth muscle contraction
    100673570 (ADCY2)
  09154 Digestive system
   04970 Salivary secretion
    100673570 (ADCY2)
   04971 Gastric acid secretion
    100673570 (ADCY2)
   04972 Pancreatic secretion
    100673570 (ADCY2)
   04976 Bile secretion
    100673570 (ADCY2)
  09156 Nervous system
   04724 Glutamatergic synapse
    100673570 (ADCY2)
   04727 GABAergic synapse
    100673570 (ADCY2)
   04725 Cholinergic synapse
    100673570 (ADCY2)
   04723 Retrograde endocannabinoid signaling
    100673570 (ADCY2)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100673570 (ADCY2)
  09149 Aging
   04211 Longevity regulating pathway
    100673570 (ADCY2)
   04213 Longevity regulating pathway - multiple species
    100673570 (ADCY2)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100673570 (ADCY2)
   04714 Thermogenesis
    100673570 (ADCY2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100673570 (ADCY2)
  09165 Substance dependence
   05032 Morphine addiction
    100673570 (ADCY2)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    100673570 (ADCY2)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100673570 (ADCY2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100673570 (ADCY2)
   05163 Human cytomegalovirus infection
    100673570 (ADCY2)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100673570 (ADCY2)
Enzymes [BR:lav01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     100673570 (ADCY2)
SSDB
Motif
Pfam: Guanylate_cyc DUF1053 AC_N HNOBA
Other DBs
NCBI-GeneID: 100673570
NCBI-ProteinID: XP_010586365
LinkDB
Position
Unknown
AA seq 1089 aa
MWREAMRRRRYLRDGAEAAAGGGRPRSGDWLYESYYCMSQQHPLIVFLLLIVMGACLALL
AVFFALGLEVEDHVAFLITVPTALAIFFAIFILVCIESVFKKLLRLFSLVIWICLVAMGY
LFMCFGGTVSPWDQVSFFLFIIFGGNTMLPFNMRDAIIASVLTSASXTIVLSVCLSATPG
TREHLVWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKLEFEKRQQER
LLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILYADIVGFTRL
ASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKNCVKMG
LDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVP
GRVHISSVTLEHLNGAYKVEEGDGDIRDPYLKQHLVKTYFVINPKGERRSPQHLFRPRHT
LDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGRHNFQNRTLRT
KSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLFFYNKILEKEYRATALPAFKY
YVTCACLIFFCIFLVQILVLPKTTILGLSFGAAFLSLTFILFVCFAGQLLRCSKKASTLL
RWLLKSSGIIANRPWPRVSLTVITTAIVLTMAVFNMFFLSNPEEAIPPTANTSNTSFPAS
NDQVAILRAQNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMTAALVGYNTILLHTHA
HVLDGYSQVLFQRPGIWKDLKTMGSVSLFIFFITLLVLGRQNEYYCRLDFLWKNKFKKER
EEIETMENLNRVLLENVLPAHVAEHFLARSLKNEDLYHQSYDCVCVMFASIPDFKEFYTE
SDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQELAQE
PERQYLHIGTMVEFAFALVAKLEAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQYDIWG
NTVNVASRMDSTGVLDKIQVTEETSLVLQTLGYTCSCRGIINVKGKGELKTYFVNTEMSR
SLSQSNLAS
NT seq 3270 nt   +upstreamnt  +downstreamnt
atgtggcgggaggcgatgcggcggcgccgctacctgcgggacggcgccgaggcggcggcg
ggcggcgggcggccgcgctccggggactggctctacgagtcctactactgcatgagccag
cagcacccgctcatcgtcttcctgctgctcatcgtcatgggcgcctgcctggccctgctc
gccgtcttcttcgcgctcgggctggaggtggaagaccatgtggcatttttaataacggtt
cccacggccctggcaatcttcttcgcgatatttatccttgtctgcattgagtccgtgttt
aagaagctgctccgtcttttctctttggtgatatggatatgtcttgttgccatgggatac
ctgttcatgtgttttggaggcaccgtctctccttgggaccaggtgtccttcttcctcttc
atcatttttggggggaacaccatgctgcccttcaacatgcgagatgccatcatcgccagc
gtcctcacctccgcctcgnacaccatcgtgctcagcgtctgcctgtctgcgacgccgggg
accagggagcacttggtctggcagatactggccaacgtgatcattttcatctgcgggaac
ctggcgggcgcctaccacaagcatctcatggagctggctctgcagcagacctatcaggac
acctgtaattgtatcaagtcccgcatcaagttggagtttgaaaaacgtcagcaggagcgt
cttctcctctccttgctgccagctcatatagccatggaaatgaaagctgagatcatccag
aggctacagggccccaaagcgggacagatggagaacaccaacaacttccacaacctgtac
gtcaagaggcacaccaatgtcagcatcttgtacgctgacattgtcgggttcacgcggctg
gcgagtgactgctccccaggagagcttgtccacatgctgaatgaactctttgggaagttt
gatcagattgcaaaggagaacgaatgcatgagaataaagattctaggagactgctactac
tgcgtgtctggcctccccatatcactccccaaccacgccaagaactgtgtgaaaatggga
ttggacatgtgcgaagccatcaagaaagtgagggatgccaccggagtcgacatcaacatg
cgtgtgggcgtgcactctgggaatgtgctctgtggcgtgatcgggctgcagaagtggcag
tacgatgtgtggtcacatgacgtcacgctcgccaaccacatggaagccggaggggtcccc
gggcgtgttcacatttcttcggtgaccttggagcacttgaatggagcttacaaggtggaa
gagggagacggtgatatcagggacccgtatttaaaacagcacctggtgaaaacctacttt
gtcatcaaccccaagggagaacgacggagcccccagcacctcttccggccccgccacacc
ctggacggagccaagatgagggcatctgtgcgcatgacccggtacttggagtcctgggga
gcagccaagcccttcgcacacctgcaccacagggacagcatgaccaccgagaacggcaag
atcagcaccacggatgtaccaatgggccggcataattttcagaatcgcactttaagaacc
aagtcacaaaagaaaagatttgaagaagaattgaatgaaaggatgatccaagccattgac
ggaatcaatgctcagaagcagtggctcaaatccgaagacatccagagaatctcgctattt
ttctacaataaaatactggaaaaagaataccgagcaacggccctgccagcattcaagtac
tacgtgacctgcgcctgcctcatcttcttctgcatcttcctcgtgcagatcctcgtgtta
cccaaaaccaccatcctgggactttcctttggagctgcatttctctcactcaccttcatc
ctgttcgtctgcttcgctgggcagcttctgcggtgcagtaagaaggcatccaccttgctc
aggtggctcctgaagtcgtcgggcatcatcgccaaccggccctggccgcgggtctccctc
actgtcatcaccacagccatcgtcctgaccatggccgtgttcaacatgtttttcctgagc
aatccagaagaagctatccctccaactgccaatacatcgaacacaagttttcctgcctca
aacgatcaggtggctattcttcgtgcgcaaaatttgtttttcctcccgtactttatatac
agctgcatcctgggactgatctcctgctcggtgttcctgcgggtgaactatgagctgaag
atgctaatcatgacggccgccttggtgggctacaacaccatcctgctccacactcatgcc
cacgtgctggacggctacagccaggtcttattccagagaccaggcatttggaaagactta
aagaccatgggctccgtgtctctctttatattcttcatcacactgcttgtcctgggtcgg
cagaatgaatattactgtaggttagatttcctgtggaagaacaagttcaaaaaagagcgg
gaggagatcgagaccatggagaacctgaaccgcgtgctgctggagaatgtgcttcccgcc
cacgtggctgagcacttcctggcacggagcctgaagaacgaggacctgtaccaccaatcc
tatgattgtgtctgcgtcatgtttgcctccatcccagatttcaaagaattttacaccgaa
tcagatgtgaacaaggagggcttggagtgccttcggctcctgaacgagatcattgctgat
tttgatgatctgttgtccaagccgaaattcagtggagtagaaaagatcaagaccatcggc
agcacatacatggcggcgacgggtctgagcgcggtgcccagccaggagcttgcccaggag
ccagagaggcagtacctgcacattggcaccatggtggaatttgccttcgcgctggtggcg
aagttggaggccatcaacaagcactccttcaacgacttcaagctgcgagtgggtattaac
cacgggcctgtaatcgctggtgtaattggcgctcagaaaccacagtatgacatttggggc
aacaccgtcaatgtggccagtcggatggacagcacgggcgtcctggataaaatacaggtg
actgaggaaacaagccttgtcctccagaccctcgggtacacctgctcctgtcgagggata
atcaacgtgaaaggcaaaggggagctgaagacgtactttgtgaacacggagatgtcccgg
tctctctcccagagcaacctggcgtcctga

KEGG   Loxodonta africana (African savanna elephant): 100674724
Entry
100674724         CDS       T04351                                 

Gene name
ADCY3
Definition
(RefSeq) adenylate cyclase type 3
  KO
K08043  adenylate cyclase 3 [EC:4.6.1.1]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav00230  Purine metabolism
lav01100  Metabolic pathways
lav01522  Endocrine resistance
lav04015  Rap1 signaling pathway
lav04020  Calcium signaling pathway
lav04022  cGMP-PKG signaling pathway
lav04024  cAMP signaling pathway
lav04062  Chemokine signaling pathway
lav04072  Phospholipase D signaling pathway
lav04114  Oocyte meiosis
lav04211  Longevity regulating pathway
lav04213  Longevity regulating pathway - multiple species
lav04261  Adrenergic signaling in cardiomyocytes
lav04270  Vascular smooth muscle contraction
lav04371  Apelin signaling pathway
lav04540  Gap junction
lav04611  Platelet activation
lav04713  Circadian entrainment
lav04714  Thermogenesis
lav04723  Retrograde endocannabinoid signaling
lav04724  Glutamatergic synapse
lav04725  Cholinergic synapse
lav04727  GABAergic synapse
lav04740  Olfactory transduction
lav04750  Inflammatory mediator regulation of TRP channels
lav04911  Insulin secretion
lav04912  GnRH signaling pathway
lav04913  Ovarian steroidogenesis
lav04914  Progesterone-mediated oocyte maturation
lav04915  Estrogen signaling pathway
lav04916  Melanogenesis
lav04918  Thyroid hormone synthesis
lav04921  Oxytocin signaling pathway
lav04923  Regulation of lipolysis in adipocytes
lav04925  Aldosterone synthesis and secretion
lav04926  Relaxin signaling pathway
lav04927  Cortisol synthesis and secretion
lav04928  Parathyroid hormone synthesis, secretion and action
lav04934  Cushing syndrome
lav04935  Growth hormone synthesis, secretion and action
lav04962  Vasopressin-regulated water reabsorption
lav04970  Salivary secretion
lav04971  Gastric acid secretion
lav04972  Pancreatic secretion
lav04976  Bile secretion
lav05032  Morphine addiction
lav05163  Human cytomegalovirus infection
lav05166  Human T-cell leukemia virus 1 infection
lav05200  Pathways in cancer
lav05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:lav00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    100674724 (ADCY3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100674724 (ADCY3)
   04371 Apelin signaling pathway
    100674724 (ADCY3)
   04020 Calcium signaling pathway
    100674724 (ADCY3)
   04072 Phospholipase D signaling pathway
    100674724 (ADCY3)
   04024 cAMP signaling pathway
    100674724 (ADCY3)
   04022 cGMP-PKG signaling pathway
    100674724 (ADCY3)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100674724 (ADCY3)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    100674724 (ADCY3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100674724 (ADCY3)
   04062 Chemokine signaling pathway
    100674724 (ADCY3)
  09152 Endocrine system
   04911 Insulin secretion
    100674724 (ADCY3)
   04923 Regulation of lipolysis in adipocytes
    100674724 (ADCY3)
   04912 GnRH signaling pathway
    100674724 (ADCY3)
   04913 Ovarian steroidogenesis
    100674724 (ADCY3)
   04915 Estrogen signaling pathway
    100674724 (ADCY3)
   04914 Progesterone-mediated oocyte maturation
    100674724 (ADCY3)
   04921 Oxytocin signaling pathway
    100674724 (ADCY3)
   04926 Relaxin signaling pathway
    100674724 (ADCY3)
   04935 Growth hormone synthesis, secretion and action
    100674724 (ADCY3)
   04918 Thyroid hormone synthesis
    100674724 (ADCY3)
   04928 Parathyroid hormone synthesis, secretion and action
    100674724 (ADCY3)
   04916 Melanogenesis
    100674724 (ADCY3)
   04925 Aldosterone synthesis and secretion
    100674724 (ADCY3)
   04927 Cortisol synthesis and secretion
    100674724 (ADCY3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100674724 (ADCY3)
   04270 Vascular smooth muscle contraction
    100674724 (ADCY3)
  09154 Digestive system
   04970 Salivary secretion
    100674724 (ADCY3)
   04971 Gastric acid secretion
    100674724 (ADCY3)
   04972 Pancreatic secretion
    100674724 (ADCY3)
   04976 Bile secretion
    100674724 (ADCY3)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    100674724 (ADCY3)
  09156 Nervous system
   04724 Glutamatergic synapse
    100674724 (ADCY3)
   04727 GABAergic synapse
    100674724 (ADCY3)
   04725 Cholinergic synapse
    100674724 (ADCY3)
   04723 Retrograde endocannabinoid signaling
    100674724 (ADCY3)
  09157 Sensory system
   04740 Olfactory transduction
    100674724 (ADCY3)
   04750 Inflammatory mediator regulation of TRP channels
    100674724 (ADCY3)
  09149 Aging
   04211 Longevity regulating pathway
    100674724 (ADCY3)
   04213 Longevity regulating pathway - multiple species
    100674724 (ADCY3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100674724 (ADCY3)
   04714 Thermogenesis
    100674724 (ADCY3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100674724 (ADCY3)
  09165 Substance dependence
   05032 Morphine addiction
    100674724 (ADCY3)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    100674724 (ADCY3)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100674724 (ADCY3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100674724 (ADCY3)
   05163 Human cytomegalovirus infection
    100674724 (ADCY3)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100674724 (ADCY3)
Enzymes [BR:lav01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     100674724 (ADCY3)
SSDB
Motif
Pfam: Guanylate_cyc AC_N HNOBA NCE101
Other DBs
NCBI-GeneID: 100674724
NCBI-ProteinID: XP_003411966
LinkDB
Position
Unknown
AA seq 1142 aa
MPRNQGFSDPEYSAEYSAEYSVSLPSDPDRAVGRTHEISVRSSGSCLCLPRFMRLTFVPE
SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSKDMLAPLIVAGIGLVLDII
LFVLCKKGVLPDRVTRKVVPYLLWLLITAQIFSYLGLNFAQAHTASDTVGWQAFFIFSFF
ITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDQLKGIQLLREILANVFLYLCAIIVG
IMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES
QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ
LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV
LGGVLGQKRWQYDVWSTDVTVANKMESGGIPGRVHISQSTMDCLKGEFDVEPGDGGSRCD
YLEEKGIETYLIIASKPEVKKTATQNGLNGSALPNGAPPFSKPSSPALIETKEPDGITTG
SISEEAEEHDAQADNPSFPNPRRRLHLQDLADRVVDASEDEHELNQLLNEALLERESAQV
VKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTALVEILIDPGLMTNYV
TFVVGEVLLLVLTICSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMANVV
DMLSCLQYYTGPSNRTTGMEEQDGCVANPKYYNYVAVLSLIATIMLVQVSHMVKLTLMLL
VTGAVAVINLYAWCPIFDEYDHRRFREHEVPITLEKMQVSSAPGLNGTDRLPLMPSKYSM
TVMMFVMLLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVANMLPEHVAR
HFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDFDSL
LDNPKFRIITKIKTIGSTYMAASGVTPDVNTNGFTGSNKEEKSEKERWQHLADLADFALA
MKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVMGN
IQVVEETQAILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKPAAFPNGSSVTLPHQVVD
NS
NT seq 3429 nt   +upstreamnt  +downstreamnt
atgcctcggaatcagggcttctctgatcccgagtactcagctgagtactcggctgaatac
tccgtcagcctgccctctgaccctgatcgagcggtgggccggacccatgaaatctccgtc
cggagctcggggtcttgcctctgcctgcctcgcttcatgcggctgaccttcgtgcctgag
tccttggagaacctctaccagacgtacttcaaaaggcagcgccatgagaccctgctggtg
ctggtggttttcgcagccctcttcgactgctacgtggtggtcatgtgcgccgtggtcttc
tccaaagacatgctggcgcccctcatcgtggccgggattggactggtgttggacatcatc
cttttcgtgctctgcaaaaagggggtgctccctgaccgggtcacccgcaaagtggtgccc
tacctgctgtggctgctgataacagcccagatcttctcctacctgggcctgaactttgcc
caggcccacacagccagcgacacggtgggttggcaggccttcttcatcttctccttcttc
atcacgctgcccctcagtctcagccccatcgtgatcatctcagttgtctcctgcgttgta
cacacgcttgtcttgggggtcaccgtggcccagcagcagcaggaccagctaaaggggatc
cagttgctgagggagatcctggccaacgtcttcctctacctgtgtgccatcatcgtgggc
atcatgtcttactacatggcagaccgcaagcaccgcaaggccttcctggaggctcgccag
tcgctggaagtgaagatgaacctggaagagcagagccagcagcaggagaaccttatgctt
tccatcctgcccaagcacgtggctgacgagatgttgaaggacatgaagaaagatgagagc
cagaaggaccagcagcagttcaacaccatgtacatgtaccgtcacgagaacgtcagcatc
ctctttgctgatatcgtgggcttcacccagctgtcctctgcctgcagtgcgcaggagcta
gtgaagcttctcaacgagctctttgcccgctttgacaagctggcagcgaaataccaccag
ctgcggattaagatcctgggtgactgttactactgcatctgtggcctgcctgactaccgg
gaggaccacgctgtctgctccatcctcatggggctggccatggtggaggccatctcgtat
gtgcgggagaagacaaagactggggtggacatgcgtgtgggggtgcacacgggcaccgtg
ttgggtggcgtcctgggccagaagcgctggcagtatgatgtgtggtccaccgacgtcacc
gtggccaacaagatggagtcaggcggcatcccagggcgcgtgcatatctcccagagcacc
atggactgcctgaaaggagagtttgacgtggagccaggcgatggaggcagccgctgcgat
tacctggaggagaagggcatcgaaacctacctcatcattgcatccaagccagaggtgaag
aaaacagccacccaaaatggcctcaacggctcggccctgccaaatggagcaccacctttc
tcaaagcccagctctcctgccctcatcgagaccaaggagcctgatgggatcaccaccgga
tctatatcggaggaggctgaggagcatgatgcccaggcagacaacccctcattccccaac
ccccgtcggaggctgcaccttcaggacctggctgatcgcgtggtggacgcctctgaggac
gaacatgagcttaaccagctgctcaacgaggccctgctggagcgagagtctgcacaggta
gtaaagaagagaaacaccttcctcctgtccatgcggtttatggacccggaaatggaaacc
cgctactcggtggagaaggaaaagcagagtggggccgccttcagctgctcctgcgttgtc
ctactctgtacagcgctggtcgagatactcatcgaccccgggctaatgacaaactacgtg
acctttgtggttggggaggttctgctcctggtcttgacaatctgctcgctggctgccatc
tttccccgggcctttcctaagaagctcgtggctttctcaacatggatcgaccggacccgc
tgggccaggaacacctgggccatgttagccatcttcattctggttatggcaaacgttgtg
gacatgcttagctgtctccagtactacacggggcccagcaacaggactacagggatggag
gagcaggacggctgcgtggcgaaccccaagtactacaactatgttgctgtgctgtccctc
atcgccaccatcatgctggtgcaggtcagccacatggtgaagctcacactcatgctgctc
gtcacaggcgcggtggccgtcatcaacctctatgcctggtgccccatctttgatgaatac
gaccacagacgttttcgggagcatgaggttcccatcaccttagagaagatgcaggtatct
tctgcccctgggctcaatgggaccgacaggctgcccctgatgccttccaagtactcaatg
acagtgatgatgttcgtcatgctgctgagcttttactacttctcccgccacgtggaaaaa
ctggcacggaccctgttcttgtggaagattgaggtccatgaccagaaggaacgtgtttat
gagatgcgacgctggaatgaggccttggtcgccaacatgttgcctgagcacgtggcccgc
catttcctgggttccaagaagagagatgaggagctgtacagccagtcttacgatgagatt
ggagtcatgtttgcttccttgcccaactttgctgacttctacacagaggagagcatcaat
aacggtggcattgagtgtctacgctttctcaatgaaatcatctcagatttcgactctctc
ctggacaatcccaaatttcggatcattaccaagatcaaaaccattggcagtacctatatg
gcagcttcaggagtcaccccagatgtcaacaccaacggttttactggctccaacaaggag
gaaaagtcggagaaggagcgctggcagcacctggctgatctggctgactttgcactggcc
atgaaggacacgcttacaaacatcaacaaccagtccttcaacaacttcatgctgcgcata
ggcatgaacaaaggaggggtactggctggcgtcattggagcccggaagccacactacgac
atctggggcaatacagtcaatgtagccagcaggatggagtccacgggggtcatgggcaac
atccaggtagtagaagaaacacaagccattctccgagagtacggtttccgcttcgtgagg
cgaggtcctatctttgtgaaggggaagggggagctgctgacctttttcctgaaggggcgc
gataagccagctgccttcccgaatggctcctctgtcacactgccccaccaggtggtagac
aactcctga

KEGG   Loxodonta africana (African savanna elephant): 100675525
Entry
100675525         CDS       T04351                                 

Gene name
ADCY4
Definition
(RefSeq) adenylate cyclase type 4
  KO
K08044  adenylate cyclase 4 [EC:4.6.1.1]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav00230  Purine metabolism
lav01100  Metabolic pathways
lav01522  Endocrine resistance
lav04015  Rap1 signaling pathway
lav04020  Calcium signaling pathway
lav04022  cGMP-PKG signaling pathway
lav04024  cAMP signaling pathway
lav04062  Chemokine signaling pathway
lav04072  Phospholipase D signaling pathway
lav04114  Oocyte meiosis
lav04211  Longevity regulating pathway
lav04213  Longevity regulating pathway - multiple species
lav04261  Adrenergic signaling in cardiomyocytes
lav04270  Vascular smooth muscle contraction
lav04371  Apelin signaling pathway
lav04540  Gap junction
lav04611  Platelet activation
lav04713  Circadian entrainment
lav04714  Thermogenesis
lav04723  Retrograde endocannabinoid signaling
lav04724  Glutamatergic synapse
lav04725  Cholinergic synapse
lav04727  GABAergic synapse
lav04742  Taste transduction
lav04750  Inflammatory mediator regulation of TRP channels
lav04911  Insulin secretion
lav04912  GnRH signaling pathway
lav04913  Ovarian steroidogenesis
lav04914  Progesterone-mediated oocyte maturation
lav04915  Estrogen signaling pathway
lav04916  Melanogenesis
lav04918  Thyroid hormone synthesis
lav04921  Oxytocin signaling pathway
lav04923  Regulation of lipolysis in adipocytes
lav04925  Aldosterone synthesis and secretion
lav04926  Relaxin signaling pathway
lav04927  Cortisol synthesis and secretion
lav04928  Parathyroid hormone synthesis, secretion and action
lav04934  Cushing syndrome
lav04935  Growth hormone synthesis, secretion and action
lav04970  Salivary secretion
lav04971  Gastric acid secretion
lav04972  Pancreatic secretion
lav04976  Bile secretion
lav05032  Morphine addiction
lav05163  Human cytomegalovirus infection
lav05166  Human T-cell leukemia virus 1 infection
lav05200  Pathways in cancer
lav05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:lav00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    100675525 (ADCY4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100675525 (ADCY4)
   04371 Apelin signaling pathway
    100675525 (ADCY4)
   04020 Calcium signaling pathway
    100675525 (ADCY4)
   04072 Phospholipase D signaling pathway
    100675525 (ADCY4)
   04024 cAMP signaling pathway
    100675525 (ADCY4)
   04022 cGMP-PKG signaling pathway
    100675525 (ADCY4)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100675525 (ADCY4)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    100675525 (ADCY4)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100675525 (ADCY4)
   04062 Chemokine signaling pathway
    100675525 (ADCY4)
  09152 Endocrine system
   04911 Insulin secretion
    100675525 (ADCY4)
   04923 Regulation of lipolysis in adipocytes
    100675525 (ADCY4)
   04912 GnRH signaling pathway
    100675525 (ADCY4)
   04913 Ovarian steroidogenesis
    100675525 (ADCY4)
   04915 Estrogen signaling pathway
    100675525 (ADCY4)
   04914 Progesterone-mediated oocyte maturation
    100675525 (ADCY4)
   04921 Oxytocin signaling pathway
    100675525 (ADCY4)
   04926 Relaxin signaling pathway
    100675525 (ADCY4)
   04935 Growth hormone synthesis, secretion and action
    100675525 (ADCY4)
   04918 Thyroid hormone synthesis
    100675525 (ADCY4)
   04928 Parathyroid hormone synthesis, secretion and action
    100675525 (ADCY4)
   04916 Melanogenesis
    100675525 (ADCY4)
   04925 Aldosterone synthesis and secretion
    100675525 (ADCY4)
   04927 Cortisol synthesis and secretion
    100675525 (ADCY4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100675525 (ADCY4)
   04270 Vascular smooth muscle contraction
    100675525 (ADCY4)
  09154 Digestive system
   04970 Salivary secretion
    100675525 (ADCY4)
   04971 Gastric acid secretion
    100675525 (ADCY4)
   04972 Pancreatic secretion
    100675525 (ADCY4)
   04976 Bile secretion
    100675525 (ADCY4)
  09156 Nervous system
   04724 Glutamatergic synapse
    100675525 (ADCY4)
   04727 GABAergic synapse
    100675525 (ADCY4)
   04725 Cholinergic synapse
    100675525 (ADCY4)
   04723 Retrograde endocannabinoid signaling
    100675525 (ADCY4)
  09157 Sensory system
   04742 Taste transduction
    100675525 (ADCY4)
   04750 Inflammatory mediator regulation of TRP channels
    100675525 (ADCY4)
  09149 Aging
   04211 Longevity regulating pathway
    100675525 (ADCY4)
   04213 Longevity regulating pathway - multiple species
    100675525 (ADCY4)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100675525 (ADCY4)
   04714 Thermogenesis
    100675525 (ADCY4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100675525 (ADCY4)
  09165 Substance dependence
   05032 Morphine addiction
    100675525 (ADCY4)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    100675525 (ADCY4)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100675525 (ADCY4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100675525 (ADCY4)
   05163 Human cytomegalovirus infection
    100675525 (ADCY4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100675525 (ADCY4)
Enzymes [BR:lav01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     100675525 (ADCY4)
SSDB
Motif
Pfam: Guanylate_cyc DUF1053 AC_N CD52
Other DBs
NCBI-GeneID: 100675525
NCBI-ProteinID: XP_010598850
LinkDB
Position
Unknown
AA seq 1075 aa
MAGLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLVIVLCALVALFAVSWASGRELASDPG
FLTTVVCALGGFSLLLGLASCEQRLQRWTRPLSGLVWAALLALGHGFLFTGGVVSAWDQV
SFFLFVIFTVYAMLPLGMRDAAAAGLVSSLSHLLALGLYLGPQPDSRPALLPQLVANAVL
FLCGNVAGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK
AEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE
LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG
VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAG
AYAVEDAAMEHRDPYLRELGEPTYLVIDPRAEEDEKGTAGGLLSSLEGPKMRPSLLMTRY
LESWGAAKPFAHLSHIDSPVSTSTPLPEKALASFSPQWSLDRSRTPRGLDDELDTGDAKF
FQVIEQLNSQKQWKQSKDFNPLTLYFRKKEMEKEYRLSALPAFKYYAACTFLVFLSNFII
QMLVTNRPPALAITYSITFLLFLLLLFVCFSEHLTRCVLKGPKMLHWLPALSGLVATRPG
LRVALGTATLKPLSPYLLLQFLLPASSNCPFRAANVSAMAFNLSWELPGSLPLISVPYSM
HCCVLGFLSCSLFLHMSFELKLLLLLLWLAASCSLFLHSHAWLSDCLIARLYMGSLDSRP
GVLKEPKLMGVISFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLTRLLL
ENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLRLL
NEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDAQQDAERSCSHLGTMVEF
AVALGCKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGV
LGKIQVTEETARALQSLGYTCYRRGIIKVKGKGQLCTYFLNTDLTRAGPPSATLG
NT seq 3228 nt   +upstreamnt  +downstreamnt
atggccggcctcttcagtcctcggccgccccccagcgaagacctcttctacgagacctac
tacagcctaagccagcagtacccgctgctgctactgctgctggtaatcgtgctctgcgcg
ctggtggcgctgttcgccgtctcctgggccagcggcagggagctggcctctgacccgggc
ttcctgaccaccgtggtgtgcgcactgggcggcttctcgctgctgctggggctggcttcc
tgcgagcagcgactgcagcgctggacgcgtcccctgtctggcctggtgtgggccgcgctg
cttgcgctaggccacggcttcctattcaccgggggcgtggtcagtgcttgggaccaggtg
tccttctttctcttcgttatcttcacggtgtacgccatgttgcccctgggtatgcgggac
gccgccgccgcgggcctcgtctcctcactctctcacctgcttgcccttggactgtacctt
gggccccagccagactcacggccagcgctgctgccccagctagtggcaaatgcggtgctg
ttcctgtgcgggaacgtggctggagcgtaccacaaggcgctgatggagcgcgcgctgcgt
gccacgttccgggaggcgctcagctccctacactcacgccggcggctggacaccgagaag
aagcaccaggaacaccttctcttgtccatccttcctgcctacctggcccgagagatgaag
gcagagatcatggcccggctgcaggctggacaggggtcacggcctgagagcaccaacaat
ttccacagcctctatgtcaagaggcaccagggagtcagcgtgctgtatgcggacatagtg
ggcttcacacgactagccagcgagtgctcccccaaggagctggtgctcatgctcaatgaa
ctctttggcaagttcgaccagattgccaaggagcatgagtgcatgcggatcaagattctg
ggagactgttactactgtgtctctgggttgcccctctccttgccagaccatgccatcaac
tgtgtgcgcatggggctggacatgtgccgggccatcaggaaacttcgggcagccaccggc
gtggacatcaacatgcgtgtgggcgtgcactcgggcagtgtgctctgtggagtcattggc
ttgcagaaatggcaatatgatgtctggtcccatgatgtcaccctggccaaccacatggag
gcaggcggtgtgccaggacgagtgcacatcacaggggccaccctggccctgctggcaggg
gcttatgctgtggaggatgcagccatggaacaccgggacccataccttcgggagctaggg
gagcctacctacctggtcatcgatccccgggctgaggaggatgagaagggcactgcagga
gggttgttgtcctctctggagggccccaagatgcgtccatcactgctgatgacccgctat
ctggagtcctggggtgcagccaagccttttgctcacctgagccacatagacagccctgta
tccacctccacccctctcccggagaaggccctagcttccttcagcccccagtggagcctg
gaccggagccgtaccccccggggactagatgatgaactagacactggggatgccaagttc
ttccaggtcatcgagcagctcaactctcagaaacagtggaaacaatcgaaggatttcaac
ccactgacactgtacttcagaaagaaggagatggagaaggagtaccggctctctgcactc
cccgccttcaaatactatgcagcctgcaccttcctggtttttctctccaatttcatcatc
cagatgctggtgacaaacaggcctccagctctggccatcacctatagcatcaccttcctc
ctcttcctcctcctcctctttgtctgcttctcagagcacctgacgaggtgtgtcctgaaa
ggccccaagatgctgcactggctgcctgcactgtctggcctggtggccacgcggcccggc
ttgcgagtcgccctgggcacggccacccttaagcccttatctccttatctcctactgcag
ttcctcttaccagcatcatccaactgccctttccgggctgccaatgtgtccgccatggct
ttcaacctctcctgggagcttcctgggtccttgcctctcatcagtgtcccgtactccatg
cactgctgtgttctgggtttcctctcctgctcccttttcctacacatgagcttcgaattg
aagctgctgctgctcctgctgtggctggcagcctcctgctccctcttcctgcactcccat
gcctggctgtctgactgcctcatcgcccgcctctatatgggttccttggactccaggcca
ggggtgctgaaggagcccaaactgatgggagtcatctctttcttcatctttttcttcacc
ctcctcgtcctggctcggcagaatgagtattactgccgcctggacttcctgtggaagaag
aagctgaggcaggagagagaagagacagagacaatggagaaccttactcggctgctcttg
gagaatgtgctccctgcacacgtggccccccagttcattggccaaaaccggcgcaatgag
gacctctaccaccagtcctatgagtgtgtttgtgtcctcttcgcctcagtcccggacttc
aaggagttttactctgaatccaacatcaaccacgaggggctggagtgtctgcgactgctc
aacgagataattgctgattttgatgagctgctctccaagcccaagttcagtggggtagag
aaaatcaaaaccatcggcagcacctacatggcagccacaggtttaaatgccacctctgga
caggatgcacagcaggatgctgaacgaagttgcagccaccttggcaccatggtggaattt
gcagtggctctggggtgtaaactggatgtcatcaacaagcactcattcaacaacttccgc
ctgcgtgtggggttgaaccatggaccagtagtggctggtgtgattggagcccaaaagcca
caatatgacatctggggcaacacagtgaatgtggccagccgcatggagagtacaggggtc
ctgggcaagatccaagtgactgaggagacagcccgggccctgcaatccctgggctatacc
tgctacaggcggggcatcatcaaagtcaaaggcaaagggcagctttgcacatactttctg
aacacagacttaacacgcgctggacccccctcagccaccctaggctaa

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