Loxodonta africana (African savanna elephant): 100653996 Help Entry 100653996         CDS       T04351                                  Gene name CACNB3 Definition (RefSeq) voltage-dependent L-type calcium channel subunit beta-3 isoform X4   KO K04864   voltage-dependent calcium channel beta-3 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04010   MAPK signaling pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav04921   Oxytocin signaling pathway lav05410   Hypertrophic cardiomyopathy lav05412   Arrhythmogenic right ventricular cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100653996 (CACNB3)  09150 Organismal Systems   09152 Endocrine system    04921 Oxytocin signaling pathway     100653996 (CACNB3)   09153 Circulatory system    04260 Cardiac muscle contraction     100653996 (CACNB3)    04261 Adrenergic signaling in cardiomyocytes     100653996 (CACNB3)  09160 Human Diseases   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100653996 (CACNB3)    05412 Arrhythmogenic right ventricular cardiomyopathy     100653996 (CACNB3)    05414 Dilated cardiomyopathy     100653996 (CACNB3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:lav04040]     100653996 (CACNB3) Ion channels [BR:lav04040]  Voltage-gated cation channels   Calcium channel, voltage-gated (Cav)    100653996 (CACNB3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_kin VGCC_beta4Aa_N SH3_1 Motif Other DBs NCBI-GeneID:  100653996 NCBI-ProteinID:  XP_003405799 UniProt:  G3TCU2 LinkDB All DBs Position Unknown AA seq 484 aa AA seqDB search MYDDSYVPGFEDSEAGSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPV AFAVRTNVSYCGTLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDITFIPS PQRLESIRLKQEQKARRSGNPSSLSDTGNRRSPPPSLAKQKQKQAEHVPPYDVVPSMRPV VLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIER SSARSSIAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVL QRLIRSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLEVYWRAT HHPAPSPGLLGPPTAIPGLQNQQLLGERGEEHSPLERDSLMPSDEASESSHQAWTGSSQR SSRHLEEDYADAYQDLYQPHRQHTSGLPSANGHDPQDRLLAQDSEHNHIDRNWQRNRPWP KDSY NT seq 1455 nt NT seq  +upstreamnt  +downstreamnt atgtatgacgactcctacgtgcccgggtttgaggactcggaggcgggttcagctgactcc tataccagccgcccatctctggactcggacgtctccctggaagaggaccgggagagtgcc cggcgcgaagtggagagccaagctcagcagcagctcgagagggccaagcacaagcccgtg gcatttgctgtgaggaccaatgtcagctactgtggcacactggatgaggagtgcccagtc cagggctctggagtcaactttgaggccaaagattttctgcacattaaagagaagtacagc aatgactggtggattgggcggctagtgaaagagggcggagacatcaccttcatccccagc ccccagcgcctggagagcatccgcctcaaacaggagcagaaggccaggagatccgggaac ccctccagcctgagtgacactggcaaccgacgctcccctcccccatctctagccaagcag aagcaaaagcaggcggaacatgttcccccatatgacgttgtgccctccatgcggcctgtg gtgctggtggggccctctctgaaaggttatgaggtcacagacatgatgcagaaggctctc ttcgactttctcaaacataggtttgatggcaggatctccatcacccgtgtcacagctgac ctctcactggcaaagcgatctgtgctcaacaatcctggcaagaggaccatcatagaacgt tcctctgcccgctccagcatcgccgaagtacagagtgagattgagcgcatattcgagctg gccaaatccctgcagctggtagtattggatgctgacaccatcaaccacccagcacagctg gccaagacctcattggcccccatcattgtctttgtcaaagtatcctcaccaaaggtactc cagcgtctcatccgctcccgggggaagtcacagatgaagcacctgaccgtacagatgatg gcatatgataagctggttcagtgtccaccggagtcatttgatgtgattctggatgagaac cagctggaggatgcctgtgagcacctggctgaatacctggaggtttattggcgggccacc caccacccagcccccagccctggtcttttgggccctcccactgccatccctggacttcag aaccagcagctgctgggggagcgtggtgaggaacactcaccactcgagcgggacagcttg atgccctcagatgaggccagcgagagctcacaccaagcctggacaggatcttcacagcgt agctcccgccacctagaagaggactatgcagatgcctaccaggacctgtaccagccacac cgccaacacacctcggggctgcccagtgctaacgggcatgacccccaggaccggctccta gcccaggactcggagcacaaccacattgaccggaactggcagcgcaaccggccctggccc aaggatagctactga

Loxodonta africana (African savanna elephant): 100656938 Help Entry 100656938         CDS       T04351                                  Gene name CACNB4 Definition (RefSeq) voltage-dependent L-type calcium channel subunit beta-4   KO K04865   voltage-dependent calcium channel beta-4 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04010   MAPK signaling pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav04921   Oxytocin signaling pathway lav05410   Hypertrophic cardiomyopathy lav05412   Arrhythmogenic right ventricular cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100656938 (CACNB4)  09150 Organismal Systems   09152 Endocrine system    04921 Oxytocin signaling pathway     100656938 (CACNB4)   09153 Circulatory system    04260 Cardiac muscle contraction     100656938 (CACNB4)    04261 Adrenergic signaling in cardiomyocytes     100656938 (CACNB4)  09160 Human Diseases   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100656938 (CACNB4)    05412 Arrhythmogenic right ventricular cardiomyopathy     100656938 (CACNB4)    05414 Dilated cardiomyopathy     100656938 (CACNB4)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:lav04040]     100656938 (CACNB4) Ion channels [BR:lav04040]  Voltage-gated cation channels   Calcium channel, voltage-gated (Cav)    100656938 (CACNB4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_kin VGCC_beta4Aa_N SH3_1 SH3_2 Motif Other DBs NCBI-GeneID:  100656938 NCBI-ProteinID:  XP_003405892 LinkDB All DBs Position Unknown AA seq 502 aa AA seqDB search MDVVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQERE QQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWI GRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTS TAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITR VTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINH PAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVI LDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQSQRM RHSNHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQHSRDHYPLVEEDYPDSYQD TYKPHRNRGSPGGYSHDSRHRL NT seq 1509 nt NT seq  +upstreamnt  +downstreamnt atggatgtggtggcccgaggcaccacgacccggaggagcaggttgaaaagatccgatggc agcaccacttcgaccagcttcatcctcagacagggttcagcggattcctacacaagcagg ccctctgactctgatgtctctttggaggaggaccgggaagccattcggcaggaaagagag cagcaagcagccatccagcttgagagagcaaagtccaaacctgtagcatttgctgtgaag acgaacgtgagctactgtggtgccctggacgaggatgtgcctgtcccaagcacagccatt tcctttgatgccaaggactttctacacattaaagagaaatataacaatgattggtggata ggaaggctggtgaaagagggctgtgagattggtttcatcccaagtccgcttagattggag aacattcggattcagcaagaacaaaaaagaggacgttttcacggagggaaatcaagtgga aattcttcttcaagtcttggagaaatggtatcagggacgtttagagcaacacccacatca acagcaaaacagaagcaaaaagtgacggagcacattcctccttacgatgttgtgccatca atgcgtccagtggtgttagtggggccgtcactgaagggttatgaggtaacagacatgatg cagaaagccctctttgatttcctgaagcacaggtttgacgggaggatatcaatcaccaga gtgaccgctgacatttctcttgctaagaggtctgtcctaaataatcccagcaagagagca ataattgaacgttcgaacacccgatccagcttagccgaagtacagagtgaaattgaaaga atctttgagttggcaagatctttgcaactggttgttcttgatgcagacaccatcaatcac ccagcacaacttataaagacttccttagcaccaattattgtccatgtaaaagtctcatct ccaaaggttttgcagcggttgattaaatctagaggaaagtcccaaagtaaacacttaaat gttcaactggtggcagctgataaacttgcacagtgtcccccagaaatgtttgatgttata ttggatgaaaatcagcttgaggatgcgtgtgaacacctgggagagtaccttgaggcatac tggcgtgctacccacaccaccagtagcacccctatgactcctctgcttggaaggaattta ggttcaacagcactctcaccgtatcctacagcaatttctgggttacagagtcagcgtatg aggcacagcaaccactccacagagaactctccaattgaaaggcgaagtttaatgacctct gatgaaaattatcacaatgaaagggctcggaagagtaggaaccgcttgtcttccagttcc caacacagccgagatcattaccctcttgtggaagaagattaccctgactcataccaggac acttacaaaccccataggaaccgaggatcacctgggggatatagccatgactcccgacac aggctttga

Loxodonta africana (African savanna elephant): 100659138 Help Entry 100659138         CDS       T04351                                  Gene name CACNA2D3 Definition (RefSeq) LOW QUALITY PROTEIN: voltage-dependent calcium channel subunit alpha-2/delta-3   KO K04860   voltage-dependent calcium channel alpha-2/delta-3 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04010   MAPK signaling pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav04921   Oxytocin signaling pathway lav05410   Hypertrophic cardiomyopathy lav05412   Arrhythmogenic right ventricular cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100659138 (CACNA2D3)  09150 Organismal Systems   09152 Endocrine system    04921 Oxytocin signaling pathway     100659138 (CACNA2D3)   09153 Circulatory system    04260 Cardiac muscle contraction     100659138 (CACNA2D3)    04261 Adrenergic signaling in cardiomyocytes     100659138 (CACNA2D3)  09160 Human Diseases   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100659138 (CACNA2D3)    05412 Arrhythmogenic right ventricular cardiomyopathy     100659138 (CACNA2D3)    05414 Dilated cardiomyopathy     100659138 (CACNA2D3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:lav04040]     100659138 (CACNA2D3) Ion channels [BR:lav04040]  Voltage-gated cation channels   Calcium channel, voltage-gated (Cav)    100659138 (CACNA2D3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  VGCC_alpha2 VWA_N VWA_3 VWA dCache_1 VWA_2 dCache_2 Cache_3-Cache_2 VWA_CoxE Phage_holin_6_1 Motif Other DBs NCBI-GeneID:  100659138 NCBI-ProteinID:  XP_003409884 LinkDB All DBs Position Unknown AA seq 1144 aa AA seqDB search MKTLIPSIAKKTNRKPAAQDSPRRFEGSQHGRPRLECCASRGASALLAXVLLYAALGEVV RSEQQIPLSVVKLWASAFGGEIKSIAAKYSGSQLLQKKYKEHEKDVAIEEIDGLQLVKKL AKNMEEMFHKKSEAVRRLVEAAEEAHLKHEFDADLQYEYFNAVLINERDKDGNFLELGKE FILAPNDHFNNLPVNISLSVVQVPTNMYNKDPAIVNGVYWSESLNKVFVDNFDRDPSLIW QYFGSAKGFFRQYPGIKWEPDENGVIAFDCRNRKWYIQAATSPKDVVILVDVSGSMKGLR LTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLVQADRTNKEHFREHLDKLF AKGIGMLDIALNEAFNILSDFNHTGQGSICSQAIMLITDGAVDTYDTIFAKYNWPDRKVR IFTYLIGREAAFADNLKWMACANKGFFTQISTLADVQENVMEYLHVLSRPKVIDQEHDVV WTEAYIDSTLPQAQKLADDQGLVLMTTVAMPVFSKQNETRSKGILLGVVGTDVPVKELLK TIPKYKLGIHGYAFAITNNGYILTHPELRPLYEEGKKRRKPNYSSVDLSEVEWEDRDDVL RNAMVNRKTGKFSMEVKKTVDKGKRVLVMTNDYYYTDIKGTPFSLGVALSRGHGKYFFRG NVTIEEGLHDLEHPDVSLADEWSYCNTDLHPEHRRLSQLEAIKLYLKGKEPLLQCDKELI QEVLFDAVVSAPIEAYWTSLALNKSENSDKGVEVAFLGTRTGLSRINLFVGAEQLTNQDF LKAGDKENIFNADHFPLWYRRAAEQIPGSFVYSIPFSTGTVNKSNVVTASTSIQLLDERK SPVVAAVGIQMKLEFFQRKFWTASRQCASLDGKCSISCDDETVNCYLIDNNGFILVSEGY TQTGDFFGEVEGAVMNKLLTMGSFKRITLYDYQAMCRANKESSDGAHGLLDPYNAFLATV KWIMTELVLFLVEFNLCSWWHSDMTARAQKLKQTLEPCDTEYPAFVSERTIKETTGNIAC EDCSKSFVIQQIPSSNLFMVVVDSSCLCESVAPITMAPIEIRYNESLKCERLKAQKIRRR PESCHGFHPEENARECGGALSVHAQQALLLLSAAFDAVVKVTLTEMFSWHAKSWINCEPK YGAT NT seq 3435 nt NT seq  +upstreamnt  +downstreamnt atgaaaacactaatcccttccatcgccaagaaaacaaacaggaaacccgcagctcaggac tccccccggcgcttcgaagggagccagcatggacggccccggctggagtgctgcgcgtcc cggggggcctcggcgctgctggccnccgtgcttctctacgccgccctgggggaagtggtg cgctccgagcagcagatcccgctttctgtggtgaagctctgggcctcggcttttggtgga gagataaaatccatcgctgctaagtactcaggctcccagctactgcaaaagaaatacaaa gaacacgagaaagacgttgccatagaggaaatcgatggcctccaacttgtgaaaaagctg gcaaagaacatggaggagatgtttcacaaaaagtctgaagcagtacggcgtcttgtggag gctgcagaggaagcacacctgaagcatgaatttgatgcagacctgcagtatgaatacttc aatgctgtgctgatcaacgagagggacaaagacgggaactttttggagctggggaaggaa ttcatcttagctcctaatgaccattttaataatttgcctgtgaacatcagtctgagtgtt gtccaagtgccaacgaacatgtacaacaaagacccagcaattgtcaatggtgtttactgg tccgaatccctgaacaaagttttcgtagataactttgaccgagacccctctctcatatgg cagtactttggaagcgcaaagggctttttcaggcagtacccagggattaaatgggaacca gatgagaatggagtgattgcctttgactgcaggaaccgaaaatggtacattcaggcagcc acttctccaaaagacgtggtcattttagtggatgtcagtggcagcatgaaaggactccgt ctgaccattgcaaagcagacggtgtcatctatcttggatacgctgggagatgacgacttc ttcaacataattgcgtataatgaggagcttcactatgtggaaccttgcctgaatggaacg ttggtacaagctgacaggacgaacaaagagcacttcagggagcatctggacaaacttttt gccaagggaatcggaatgctggatatagctctcaacgaggccttcaacatcctcagtgac ttcaatcacacaggacaaggaagtatctgcagccaagcgatcatgctcataactgatggg gcggtggacacctatgataccatctttgccaaatacaactggccagatcgaaaggttcgc atcttcacgtacctcattggacgagaggccgcgtttgcagacaacctcaagtggatggcc tgtgccaacaaaggatttttcacccagatctccaccttggccgacgtgcaggaaaatgtc atggagtacctccatgtgctcagccggcccaaagtcatcgaccaggagcacgatgtggta tggaccgaagcttacatcgacagcactctccctcaggcacaaaagcttgctgacgatcag ggcctcgtcctgatgaccacagtggccatgcctgtgtttagtaagcagaacgaaaccaga tcaaaaggcattcttctcggtgtggttggcacagatgtcccagtgaaagaacttctgaaa accatacccaaatacaagttagggattcacggttatgcctttgcaatcacaaataatgga tacattctgacgcatccagaactcaggccgctgtatgaagaaggaaaaaagcgaaggaaa cctaactatagtagcgttgacctctctgaggtcgagtgggaagacagagacgacgtgtta agaaacgccatggtgaatcggaagacaggcaagttttccatggaggtgaagaagacagtg gacaaagggaaacgggttttggtgatgacaaatgactactattatacagacatcaagggt actcctttcagtttaggtgtggcgctctccagaggccatgggaaatatttcttccgaggg aatgtaaccattgaagaaggccttcacgacctagaacaccctgatgtgtccttggcagat gaatggtcctactgcaacactgacctacacccagaacaccgtcgtctgtcacagttagaa gctattaagctctacctcaaaggcaaagaacctctgctccaatgtgataaagagctgata caagaagtcctctttgatgctgtggtgagtgctccaattgaagcgtattggaccagtctt gccctcaacaaatctgagaattctgacaagggcgtggaggttgccttcctcggtactcgc actggcctctcgagaatcaacctgtttgttggtgctgagcagctcaccaatcaggacttc ctgaaagctggagacaaggagaacatttttaacgcagaccactttccgctctggtataga agagctgcggagcagattcctgggagctttgtctactcgattccgttcagcacaggaaca gtcaacaaaagtaatgtggtgacagcaagtacctccatccagcttctagacgagcggaaa tctcccgtggtggcagctgtaggcattcagatgaaacttgaatttttccaaaggaagttc tggactgccagcagacagtgtgcctctctggatggcaaatgctccatcagctgcgatgat gagactgtgaactgttacctcatagacaacaacggatttattctggtgtcagaaggctac acacagactggagactttttcggtgaggtcgagggtgctgtgatgaataaattgttaaca atgggctcctttaaaagaattaccctttatgattaccaagccatgtgcagagctaacaag gaaagcagcgatggcgcccatggtctactggatccttataatgccttcctcgctacagta aaatggataatgacagaacttgtcttgttcctggtggaatttaacctctgcagttggtgg cactcggacatgacagctagagcccagaaattgaaacagaccctggagccttgtgacact gaataccccgcatttgtctctgagcgcaccatcaaggagaccacagggaacattgcttgt gaagactgctccaagtcctttgtcatccagcaaatcccaagcagcaatctgttcatggtg gtggtggatagcagctgcctgtgtgagtctgtggcccccatcaccatggcgcccattgaa atcaggtataatgaatcccttaagtgtgagcggttaaaggcccagaagattagaagacgt ccggaatcttgtcatggctttcatcctgaggagaacgcaagggagtgtggaggtgcactg agcgttcacgcccagcaggcccttctactgctctccgctgcttttgatgctgttgtcaag gtgacactgacggagatgttctcttggcatgctaaatcatggataaactgtgaaccaaaa tatggtgcgacatag

Loxodonta africana (African savanna elephant): 100659992 Help Entry 100659992         CDS       T04351                                  Gene name CACNA1D Definition (RefSeq) LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1D   KO K04851   voltage-dependent calcium channel L type alpha-1D Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04010   MAPK signaling pathway lav04020   Calcium signaling pathway lav04022   cGMP-PKG signaling pathway lav04024   cAMP signaling pathway lav04218   Cellular senescence lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav04270   Vascular smooth muscle contraction lav04530   Tight junction lav04713   Circadian entrainment lav04723   Retrograde endocannabinoid signaling lav04724   Glutamatergic synapse lav04725   Cholinergic synapse lav04726   Serotonergic synapse lav04727   GABAergic synapse lav04728   Dopaminergic synapse lav04911   Insulin secretion lav04912   GnRH signaling pathway lav04921   Oxytocin signaling pathway lav04924   Renin secretion lav04925   Aldosterone synthesis and secretion lav04927   Cortisol synthesis and secretion lav04929   GnRH secretion lav04930   Type II diabetes mellitus lav04934   Cushing syndrome lav04935   Growth hormone synthesis, secretion and action lav04973   Carbohydrate digestion and absorption lav05010   Alzheimer disease lav05020   Prion disease lav05022   Pathways of neurodegeneration - multiple diseases lav05031   Amphetamine addiction lav05410   Hypertrophic cardiomyopathy lav05412   Arrhythmogenic right ventricular cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100659992 (CACNA1D)    04020 Calcium signaling pathway     100659992 (CACNA1D)    04024 cAMP signaling pathway     100659992 (CACNA1D)    04022 cGMP-PKG signaling pathway     100659992 (CACNA1D)  09140 Cellular Processes   09143 Cell growth and death    04218 Cellular senescence     100659992 (CACNA1D)   09144 Cellular community - eukaryotes    04530 Tight junction     100659992 (CACNA1D)  09150 Organismal Systems   09152 Endocrine system    04911 Insulin secretion     100659992 (CACNA1D)    04929 GnRH secretion     100659992 (CACNA1D)    04912 GnRH signaling pathway     100659992 (CACNA1D)    04921 Oxytocin signaling pathway     100659992 (CACNA1D)    04935 Growth hormone synthesis, secretion and action     100659992 (CACNA1D)    04924 Renin secretion     100659992 (CACNA1D)    04925 Aldosterone synthesis and secretion     100659992 (CACNA1D)    04927 Cortisol synthesis and secretion     100659992 (CACNA1D)   09153 Circulatory system    04260 Cardiac muscle contraction     100659992 (CACNA1D)    04261 Adrenergic signaling in cardiomyocytes     100659992 (CACNA1D)    04270 Vascular smooth muscle contraction     100659992 (CACNA1D)   09154 Digestive system    04973 Carbohydrate digestion and absorption     100659992 (CACNA1D)   09156 Nervous system    04724 Glutamatergic synapse     100659992 (CACNA1D)    04727 GABAergic synapse     100659992 (CACNA1D)    04725 Cholinergic synapse     100659992 (CACNA1D)    04728 Dopaminergic synapse     100659992 (CACNA1D)    04726 Serotonergic synapse     100659992 (CACNA1D)    04723 Retrograde endocannabinoid signaling     100659992 (CACNA1D)   09159 Environmental adaptation    04713 Circadian entrainment     100659992 (CACNA1D)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     100659992 (CACNA1D)    05020 Prion disease     100659992 (CACNA1D)    05022 Pathways of neurodegeneration - multiple diseases     100659992 (CACNA1D)   09165 Substance dependence    05031 Amphetamine addiction     100659992 (CACNA1D)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100659992 (CACNA1D)    05412 Arrhythmogenic right ventricular cardiomyopathy     100659992 (CACNA1D)    05414 Dilated cardiomyopathy     100659992 (CACNA1D)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100659992 (CACNA1D)    04934 Cushing syndrome     100659992 (CACNA1D)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:lav04040]     100659992 (CACNA1D) Ion channels [BR:lav04040]  Voltage-gated cation channels   Calcium channel, voltage-gated (Cav)    100659992 (CACNA1D) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ion_trans CAC1F_C GPHH Ca_chan_IQ PKD_channel Rer1 Motif Other DBs NCBI-GeneID:  100659992 NCBI-ProteinID:  XP_023403870 LinkDB All DBs Position Unknown AA seq 2168 aa AA seqDB search MMMMMMMKKMQHQRQQADHANEANYARGTRLPLSGEGPTSQPNSSKQTVLSWQAAIDAAR QAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACIS IVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKII AYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSGGKSGGFDVKALRA FRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKTC FFADSDIVAEEDPAPCAFSGNGRQCTANDTECKSGWVGPNGGITNFDNFAFAMLTVFQCI TMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGD FQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGKRNTSMPTSETESVNTENVSG EGENQGCCASLWCWWKRRGAAKAGPSGCRRWSGLLSGFRSRRWRRWNRFSRRRCRAAVKS VTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAY FVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVAS LLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQIL TGEDWNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGWSFCIYFIILFIGGNYIL LNVFLAIAVDNLADAESLNTAQKEEAEEKERKKIARKESLENKKNNKPEVNQIANSDNKV TIDDYREEDEDKDPYPPCDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIIPIPEG SAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFD YAFTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKIL RVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYR CTDEAKSNPEECRGLFILYKDGEVDNPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGW PALLYKAIDSNGENVGPIYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEY KNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLA MQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKHYFTDAWNTFDALIVVGSVVD IAITEVNPTESENVPVPTAAPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTF IKSFQALPYVALLIAMLFFIYAVIGMQMFGKVALRDNNQINRNNNFQTFPQAVLLLFRCA TGEAWQEIMLACLPGKLCDPESDYNPGEEYTCGSNFAIVYFISFYMLCAFLIINLFVAVI MDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQHPXGFGKLCP HRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEVVPPAGDDEVTVGKFYATFL IQDYFRKFKKRKEQGLVGKHPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEEAN REEEDLFKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSIPPASDTEKPLFPPA GNSVCHNHHNHNSIGKQIPNSTNANLNNANMSKAAHGKRPSIANLEHVSDNGHHSSHKHD REPQRRSSFKRTRYYETYVRSDSGDEQLPTICWEDSEIHGYFQDPRCLGEQEYFSSEEYY EDDSSPTRSRHNNGYYNRYPGSSLDFERPRGYHHPQGFLEDDDSPVCYDRRSPRRRLLPP TPTSHRRSSFNFECLRRQGSQEEVPPSPAFPHRTALPLHLMQQQIMAVAGLDSSKVQKYS PSHSTRSWATPPATPPYQDWTPCYTPLIQVERSESLDQVNGSLPSLHRSSWYTDEPGIAY RTFTPASLTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYARDPKFVSATKHEIADACD LTIDEMESAASHLLNGNVSPRANGDVGPVSHQQDYELQDFGSGYSDEEPDPGRYEEDLAD EMICITTL NT seq 6507 nt NT seq  +upstreamnt  +downstreamnt atgatgatgatgatgatgatgaaaaaaatgcagcatcaacggcagcaagcggaccacgcg aatgaggcaaactatgcaagaggcaccagactccctctttctggtgaaggaccaacttct cagccgaatagctccaagcagactgtcctgtcttggcaagctgcaatcgatgctgctaga caggccaaggctgcccaaactatgagcacctccgcgcctccacctgtaggatctctctcc caaagaaaacgtcagcaatacgccaagagcaaaaaacagggtaactcgtccaacagccga cctgcccgtgcccttttctgtttatcactcaataaccccatccgaagagcctgcattagt atagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgtgtg gccttagctatttacatcccattccctgaagatgattctaattcaaccaaccataacttg gaaaaagtagaatatgccttcctgattatttttacagtcgagacatttttgaagattata gcttatggattattgctacatcctaatgcttatgttaggaatggatggaatttattggat tttgttatagtaatagtaggattgtttagtgtaattttggaacaattaaccaaagaaaca gaaggcggtaaccactctggtggcaaatcaggaggctttgatgtcaaagccctccgcgcc tttcgagtgttacgaccacttcgactagtatcaggagtgcccagtttacaagttgtcctg aactccattataaaagccatggttcccctccttcacatagcccttttggtattatttgta atcataatctatgctattataggattggaactttttattggaaaaatgcacaaaacatgc ttttttgctgactcagatatcgtagctgaagaggacccagcgccatgtgcgttctcaggg aatggacgccagtgtaccgccaatgacacagagtgtaagagtggctgggttggcccaaat ggaggcatcacaaactttgataactttgcctttgccatgctcaccgtgtttcagtgtatc accatggagggctggacagacgtgctctactggatgaatgatgctatgggatttgaattg ccctgggtgtattttgtcagtctcgtcatctttgggtcatttttcgtactaaatcttgta cttggtgtattgagcggagaattttcaaaggaaagagagaaggctaaagcacggggagat ttccagaagctccgggagaagcagcagctagaagaggatcttaagggctacttggattgg attacccaagcagaagacatcgatcctgagaatgaggaagaaggaggagaggaaggcaaa cgaaatactagcatgcccaccagtgagaccgagtctgtgaacacggagaacgtaagcggc gaaggcgagaaccaaggctgctgtgcaagtctctggtgctggtggaagagaagaggcgcg gccaaggctgggccttcagggtgtcggcgctggagtgggctgctctcaggcttcagatcc cgacgctggcgtcgctggaatcgattcagtcgaagaagatgtagggctgccgtgaagtct gtcacgttttactggctggttattgtcctggtgtttctcaacaccttaaccatttcctct gagcactacaaccagcctgactggttgacacagattcaagatatcgctaacaaagtcctc ttggctctgttcacctgtgagatgttggtaaaaatgtacagcttgggactccaggcgtat ttcgtctctcttttcaatcggtttgattgcttcgtggtgtgtggtggaattaccgaaact attttagtggaactggaaatcatgtctcccctgggaatctccgtgtttcggtgtgtgcgc cttttaagaattttcaaagtgaccaggcactggacttccctcagcaacctcgtggcgtcc ttgttaaactccatgaagtccatcgcttcactgctgcttctgctctttctcttcatcatc atcttttccttacttgggatgcagctgtttggcggcaagtttaattttgatgaaacgcaa accaagcggagtacttttgacaatttccctcaagcgcttttaacagtgttccagatcctg acaggtgaagactggaatnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnntc cagggatggtcgttctgcatctacttcatcatccttttcattggcggtaactatattctg ttgaatgtcttcttggccatcgccgtggacaatttggctgacgctgaaagtttgaacact gctcagaaagaggaagcagaagaaaaagagcggaaaaagattgccagaaaagagagcctg gaaaataaaaagaacaacaaaccagaagtcaaccagatagccaacagtgacaacaaggtt acaattgatgactaccgagaagaggatgaggacaaggacccctacccaccttgtgatgtg ccagtaggggaagaggaagaggaggaggaagaggatgaacccgaggtccctgctggtccc cgtcctcgcagaatctcagagttaaacatgaaggagaaaatcattcccatccctgaagga agcgctttcttcattcttagcaagaccaacccgatccgcgtgggctgccacaagctcatc aaccaccacatcttcactaaccttatcctggtcttcatcatgctgagcagcgctgccctc gcggccgaggaccccatccgcagccactccttccggaacactatactgggttactttgac tatgctttcacagccatctttactgttgaaatcctgttgaagatgacgacttttggagct ttcctccacaaaggggctttctgcaggaactacttcaatttgctggatatgctggttgtt ggggtgtctctggtgtcatttgggattcaatccagcgctatctccgttgtgaagattctg agggtcctaagggtcctcaggcccctcagggcaatcaacagagcaaaaggacttaagcat gttgtccagtgtgtctttgtggccatccggacaatcggcaacatcatgatcgtcaccacc cttctccagttcatgtttgcctgtattggggtccagttgttcaagggaaagttctatcgc tgcacagatgaagccaaaagtaaccctgaagaatgcagggggcttttcattctctacaag gatggggaggtcgataaccctgtggtgcgtgagaggatctggcagaacagtgatttcaat tttgacaacgtcctatctgctatgatggcacttttcacagtctccacatttgagggctgg cctgcattgctgtataaagctattgactcaaacggtgagaacgtcggcccgatctacaac taccgcgtggagatctccatcttcttcatcatctacatcatcattgtggctttcttcatg atgaacatctttgtgggtttcgtcatcgttacgtttcaggagcagggagaaaaagagtat aagaactgtgagctggacaaaaatcagcgtcagtgcgttgaatatgccttgaaagctcgt cctttgcggagatacatcccgaaaaacccctaccagtacaagttctggtacgtggtgaac tcctcgcctttcgaatacatgatgtttgtcctcatcatgctcaacacactctgcttggcc atgcagcactatgagcagtctaagatgtttaatgacgccatggacatcctgaacatggtc ttcactggggtgttcaccgttgagatggttttaaaagtcattgcatttaaacctaagcac tatttcactgatgcatggaacacttttgatgccttaattgttgttggtagcgtcgttgat attgctataactgaagtgaatccaactgaaagtgaaaatgtccctgtcccaactgctgca cctgggaactctgaagagagcaatagaatctccatcacctttttccgtcttttccgagtg atgcgactggtgaagcttctcagcaggggagaaggcatccggacattgctgtggactttt attaaatcctttcaggccctcccatatgtcgcccttctcatagccatgcttttcttcatc tatgctgtcatcggaatgcagatgtttgggaaagttgccctgagagataacaaccagatc aataggaataataacttccaaacctttccccaggcggtactgctgctcttcaggtgtgcc actggggaggcctggcaggaaatcatgctggcctgcctccctgggaagctgtgtgaccca gagtcagattacaaccccggggaggagtacacgtgcgggagcaattttgccatcgtttat ttcatcagtttttacatgctctgtgcatttctgatcatcaatctgtttgtggccgtcatc atggacaactttgattatctgacccgggactggtctattttgggacctcaccatttagat gaattcaaacgaatatggtcagaatatgaccctgaagcaaagggaaggataaaacacctg gacgtggtcactctgcttcgacgtatccagcaccctnnggggtttgggaaattatgccca cacagagtagcatgcaagagattagttgctatgaacatgcctctcaacagtgatgggaca gtcatgttcaatgcaaccctgtttgccttggttcgaactgctcttaaaatcaagactgaa gttgtccctccagctggtgatgatgaggtaaccgtggggaagttctatgccactttcctg atacaggactactttaggaaattcaagaaacggaaagaacaaggactggtgggaaaacac ccagcgaagaacaccacaattgccctacaggcgggattaaggacactacacgacattggg ccagaaatccggcgggctatatcctgtgatttgcaagatgatgagccagaagaagcaaac cgagaagaagaagatttgttcaaaagaaatggtgccctgcttggaaaccatgtcaatcat gttaatagtgataggagagattcccttcagcagaccaataccacccaccgtcccctgcat gtccaaaggccttcaattccacctgcaagtgatactgagaaaccgctgtttcctccagca ggaaattcggtgtgtcataaccatcataaccataattccataggaaagcaaattcccaac tcaacaaatgccaatctcaataatgccaatatgtccaaagctgcccatggcaagcggccc agcattgcgaaccttgagcatgtgtctgacaatgggcatcattcctcccacaagcatgac cgtgagcctcaaagaaggtccagttttaaaagaacccgctattatgaaacttacgttagg tccgactctggagatgaacagctcccgactatttgctgggaagattcagagatacatggc tacttccaggatccccgctgcttaggggagcaggagtatttcagcagtgaggaatactac gaggatgacagctcgccgaccagaagcaggcataacaatggctactacaacagataccca ggcagcagcttggacttcgaaaggccccgaggctaccaccacccccaaggcttcttagag gacgatgactcacccgtttgctacgatcggagatctccaaggagacgcctactacctcca accccaacatcccaccggagatcctccttcaactttgagtgcctgcggaggcagggcagc caggaagaggtcccgccgtcgccggcttttccccaccgcacagcgctgcctctgcacctc atgcagcaacagatcatggcagttgcaggcctagattcgagcaaagtccagaagtactca ccgagtcactcgacccggtcatgggccacccccccagcgacgcccccctaccaggactgg acgccctgctacacccccctgatccaggtagagcggtcagagtccctggaccaggtcaat ggcagcctgccgtccctgcaccgcagttcctggtacacagatgaacctggtatcgcctat cggactttcacgccagccagcctgactgtccccagcagcttccggaacaaaaacagcgac aagcagaggagtgcggacagcttggtggaggcagtcctcatatctgaaggcttaggacgg tatgcaagggacccgaaatttgtatcagcaacaaaacatgagattgccgatgcctgtgac ctaaccattgacgagatggagagtgcagccagccacctgctcaacgggaacgtgagtccc cgagccaatggggacgtgggccccgtctcacaccagcaggactatgagctacaagacttt ggttctggctacagcgatgaagagccagaccctgggagatatgaggaggacctggcagat gaaatgatatgcatcactaccttgtag

Loxodonta africana (African savanna elephant): 100660460 Help Entry 100660460         CDS       T04351                                  Gene name CACNG8 Definition (RefSeq) voltage-dependent calcium channel gamma-8 subunit   KO K04873   voltage-dependent calcium channel gamma-8 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04010   MAPK signaling pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav04921   Oxytocin signaling pathway lav05410   Hypertrophic cardiomyopathy lav05412   Arrhythmogenic right ventricular cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100660460 (CACNG8)  09150 Organismal Systems   09152 Endocrine system    04921 Oxytocin signaling pathway     100660460 (CACNG8)   09153 Circulatory system    04260 Cardiac muscle contraction     100660460 (CACNG8)    04261 Adrenergic signaling in cardiomyocytes     100660460 (CACNG8)  09160 Human Diseases   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100660460 (CACNG8)    05412 Arrhythmogenic right ventricular cardiomyopathy     100660460 (CACNG8)    05414 Dilated cardiomyopathy     100660460 (CACNG8)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:lav04040]     100660460 (CACNG8) Ion channels [BR:lav04040]  Voltage-gated cation channels   Calcium channel, voltage-gated (Cav)    100660460 (CACNG8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PMP22_Claudin Claudin_2 Motif Other DBs NCBI-GeneID:  100660460 NCBI-ProteinID:  XP_023399863 LinkDB All DBs Position Unknown AA seq 222 aa AA seqDB search MGSSQWEQKFARTVEVRVLVPPHPRRPLPIPAGPGGPPASACAVNPPKPPHGPAPRCPGW WPTAPRLPVVKLESLKRWNEERGLWCEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRA FICNTTNLTASDDGPPHRGPGGTSEKKDPGGLTHSGLWRICCLEGLKRGVCVKINHFPED TDYDHDSAEYLLRTTQESRSSAPSSSFKDPILPYPDLSPSEP NT seq 669 nt NT seq  +upstreamnt  +downstreamnt atgggctcaagccaatgggagcagaaatttgctaggacggtggaggtgagggtcctggtg ccacctcatcctcgccgccccctccccatccccgccggccccggggggcccccagcttct gcctgcgctgtgaacccccccaagccgccgcacggccccgccccccgctgccccgggtgg tggcccacggccccccggctgcctgtggtcaaactggagtcgctgaagcgctggaacgaa gagcggggtctctggtgcgagaagggggtgcaggttctgctgacgacggtgggcgccttc gccgcctttggcctcatgaccatcgctatcagcaccgactactggctgtacacgcgcgcc ttcatctgcaacaccaccaacctcacagccagcgacgatgggcccccccaccgcgggcct gggggcacctccgagaagaaggaccctggcggcctcacacactcaggcctctggagaatc tgctgcctggaagggttgaaaagaggcgtctgcgtgaagatcaaccacttcccggaggac acagactacgatcatgacagcgcggagtatctgctccgtacgacccaggagtcccggtcc tcagccccctcctcctccttcaaggacccaattctcccctacccagacctttctccctca gagccctag

Loxodonta africana (African savanna elephant): 100663604 Help Entry 100663604         CDS       T04351                                  Gene name CACNA2D4 Definition (RefSeq) voltage-dependent calcium channel subunit alpha-2/delta-4   KO K04861   voltage-dependent calcium channel alpha-2/delta-4 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04010   MAPK signaling pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav04921   Oxytocin signaling pathway lav05410   Hypertrophic cardiomyopathy lav05412   Arrhythmogenic right ventricular cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100663604 (CACNA2D4)  09150 Organismal Systems   09152 Endocrine system    04921 Oxytocin signaling pathway     100663604 (CACNA2D4)   09153 Circulatory system    04260 Cardiac muscle contraction     100663604 (CACNA2D4)    04261 Adrenergic signaling in cardiomyocytes     100663604 (CACNA2D4)  09160 Human Diseases   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100663604 (CACNA2D4)    05412 Arrhythmogenic right ventricular cardiomyopathy     100663604 (CACNA2D4)    05414 Dilated cardiomyopathy     100663604 (CACNA2D4)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:lav04040]     100663604 (CACNA2D4) Ion channels [BR:lav04040]  Voltage-gated cation channels   Calcium channel, voltage-gated (Cav)    100663604 (CACNA2D4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  VGCC_alpha2 VWA_N VWA_3 VWA VWA_2 dCache_1 dCache_2 VWA_CoxE Motif Other DBs NCBI-GeneID:  100663604 NCBI-ProteinID:  XP_003410807 LinkDB All DBs Position Unknown AA seq 1120 aa AA seqDB search MPGLPKFHPNPSSTHSVSPYPAWSVAWAFLQKTVVILWLLLACLPLPPTWAQTKIPLETV KLWADTFGQDLYNTVTKYSGSLLLQKKYKDVESSLKIKEVDGLALVRKFSEDMENMLRSK VEAVKRLVEAAEEADLNHEFNASLVFDYYNSVLINERDENGNFVELGAEFVLESNAHFSN LMVNTSISSVQLPTNVYNKDPDILNGVFMSEALNTVFVENFQRDPTLTWQYFGSSTGFFR IYPGIKWAPDENGVIAFDCRNRGWYIQAATSPKDIVIVVDVSGSMKGLRMAIAKHTISTI LDTLGENDFVNIIAYNEYVHYIEPCFKGILVQADRDNREHFKQLVEELMVRGVGIVNQAL SEAFQILKQFQEARQGSLCNQAIMLITDGAVEDYEPVFEKYNWPDRKVRVFTYLIGREVT FADCMKWIACNNKGYYTQISTLADAQENVMEYLHVLSRPMVINHDHDITWTEAYLDSQLF TSQAQSLMLLTTVAMPVFSKKNETRSHGILLGVVGSDVALRELMKLAPKYKLGVHGYAFL NTNNGYILSHPDLRPLYREGKKLKPKPNYNSVDLSEVEWEDQAEILRTAMINGETGSLSM NVKVPLDKGKRVLFLTNDYFFTDISDTPFSLGVVLSQGHGEYILLGNTSVEEGLHDLLHP DVTVASEWIYCITDIDPDHRKLSQLEAMVNFLTGEDADLECDEELLQEVLFDAVVTAPME AYWTGLALNMSEDSKDVDMAFLGTRAGLLRSGLFVGSEKVSNKKFLTPEDEASIFTMDHF PLWYRQAAEQPAGSFVFNLHSAEAPESPGEAAVVTASTAVAMTVDKKTAIAAAVGVQIKL EFLQRKFWAATQQCSGVDEPCPTSCQDNDLDCFVIDNNGFILISEQPQETGRFLGEVDGA FMTQLLSMGVFNQVTMYDYQAMCKPPNHHHSAAQPLTSPIPAFLTATRWLLNELLLFLLE WSAWGTWHADSGAEAKTVFHHSHKHKKQDMLQPCDTEYPVFVHQTAIQEANGIIDCGACQ KMFVMQQIPKSNLLLLVTDSTCDCSIFPPVLQEATEVKYNASVKCDRMRSQKLRRRPDSC HAFHPEENAQDCGGTSAISASLPLLLLPLCAWALLPQLLW NT seq 3363 nt NT seq  +upstreamnt  +downstreamnt atgcctggactccccaaatttcacccaaaccccagctccacccacagtgtgagcccctac cctgcatggtcagtggcctgggccttcctacagaagactgtggtcatcctgtggctgctg ctggcctgcctccccttgcctcccacttgggctcagaccaagattcctctggaaacagtg aagctgtgggcagataccttcggccaggacctgtacaacactgtgaccaaatactcaggc tccctcttgctgcagaagaaatacaaggatgtggagtccagtctgaagatcaaggaggtg gacggcttggcactggtgaggaagttctcagaggacatggagaacatgctgcggagcaaa gtggaggctgtcaagaggctggtggaggccgctgaggaggctgacctgaaccatgaattc aacgcctctctggtgtttgactattacaactccgtgctgatcaacgagagggacgagaat ggcaactttgtggagctgggagctgagtttgtcctggagtccaacgcacacttcagcaac ctgatggtgaacacctccatcagcagtgtgcagctgcccaccaacgtgtacaacaaagac cctgatattttaaacggagtcttcatgtctgaagccttgaacactgtttttgtggagaac ttccagagagacccaacattgacctggcaatattttggcagctcaactggattcttcagg atctatccaggtataaaatgggcacctgatgagaatggagtcattgcctttgactgccga aatcgtggctggtacatacaggctgctacttctcccaaggacatagtgattgtagtggac gtgagcggcagcatgaaggggctgaggatggctattgccaaacataccatctccaccatc ttggacaccctgggagagaatgatttcgttaacatcattgcgtacaacgaatatgttcat tacattgagccttgctttaaagggatcctcgtccaagcagatcgagacaaccgagagcat ttcaaacagctggtggaagagctgatggtcagaggtgtagggattgtgaaccaagccctg agtgaagccttccaaatcctcaagcagttccaggaggccaggcaaggaagcctctgtaac caggccatcatgttgatcaccgatggtgccgtggaggactatgagccagtatttgagaag tataattggccggatcgcaaggtccgagttttcacctacctcattgggagagaagtgact tttgctgactgcatgaagtggatcgcgtgcaacaacaaaggctactatacgcagatctcc acactggcagacgcccaggagaacgtgatggagtacctgcatgtgctcagccgccccatg gtcatcaaccacgaccacgacatcacctggacagaagcttacctggacagccagctcttc acctcgcaggcacagagcttgatgctcctgactactgtggccatgcctgtcttcagcaaa aagaacgaaacgcgatctcatggcattctcctgggtgtggtgggctctgatgtagccctg cgagagctgatgaagctggcacctaagtacaagctaggagtgcacggatatgcctttttg aacactaacaatggctacatcctctcccatcctgacctccggcccttgtacagagagggg aagaaactgaagcccaaacctaactacaacagcgtggatctctccgaagtggagtgggaa gaccaagctgaaatcctgagaacagccatgatcaatggggaaactggctctctgtctatg aacgtgaaggtgccactggacaaagggaagcgagtccttttcctgaccaatgattacttc ttcacagacatcagtgacacacctttcagtttgggagtggtgctatcccagggccacgga gaatacatcctcctggggaacacatcggtggaagaaggcctgcatgacctgcttcacccg gatgtgaccgtagccagtgaatggatctactgcatcacagatatcgacccagaccaccgg aagctcagccagctagaggccatggtcaacttcctgacaggggaggacgcagacctggaa tgtgacgaggagctgctgcaggaggtgctgtttgacgcagtggtgacggctcccatggaa gcctattggactgggctggctctcaacatgtctgaagactccaaggacgtggacatggcg ttcctgggcacccgggctggtcttcttagaagcggcttgttcgtgggctccgagaaggtc tctaacaagaagttcctgactcctgaagacgaggccagcatattcaccatggaccacttc cctctgtggtaccgccaggctgctgagcagccagctggcagctttgtcttcaatcttcac tcagcagaggcaccagaaagtccaggcgaggcagcagttgtaacggcaagcacagctgta gccatgacagtggacaagaagacagccattgctgcagcagtgggcgtccaaataaagctg gaattcctccaacgcaaattctgggcagcgacacaacagtgcagtggtgtggatgagccg tgcccaacaagctgccaggacaatgacctggactgcttcgtcatagacaacaatgggttc atcctgatctcagagcagccccaagagacaggaagatttctgggggaggtggatggtgct tttatgacccaactgctcagcatgggggtgttcaaccaagtgaccatgtacgactaccag gccatgtgcaagcccccgaatcaccaccacagtgcggcccagcccctgaccagcccaatc cctgcattcctgactgctaccaggtggctgctgaatgagctcttgctgttcctgctggag tggagtgcctggggcacctggcatgcggacagtggggccgaggccaaaactgttttccat cactcccacaaacataagaaacaggatatgctgcagccctgcgacacggagtaccctgtg tttgtgcaccagacagccatccaggaggccaacgggatcatcgattgtggggcctgccag aagatgtttgtgatgcaacagattcccaagagtaacctcctcctcctggtgacagactcc acgtgtgattgtagcatcttcccaccagtcctgcaggaggctacagaggtcaaatataat gcctctgtcaagtgtgacaggatgcgctcccagaagctgcgccggcgaccagactcctgc catgccttccacccagaggagaatgcccaggactgtggcggcacctcagccatctcagcc tcgctccccctgctcctactgcctctgtgtgcctgggcactactgccccagcttctgtgg tga

Loxodonta africana (African savanna elephant): 100664775 Help Entry 100664775         CDS       T04351                                  Gene name CACNG4 Definition (RefSeq) voltage-dependent calcium channel gamma-4 subunit   KO K04869   voltage-dependent calcium channel gamma-4 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04010   MAPK signaling pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav04921   Oxytocin signaling pathway lav05410   Hypertrophic cardiomyopathy lav05412   Arrhythmogenic right ventricular cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100664775 (CACNG4)  09150 Organismal Systems   09152 Endocrine system    04921 Oxytocin signaling pathway     100664775 (CACNG4)   09153 Circulatory system    04260 Cardiac muscle contraction     100664775 (CACNG4)    04261 Adrenergic signaling in cardiomyocytes     100664775 (CACNG4)  09160 Human Diseases   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100664775 (CACNG4)    05412 Arrhythmogenic right ventricular cardiomyopathy     100664775 (CACNG4)    05414 Dilated cardiomyopathy     100664775 (CACNG4)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:lav04040]     100664775 (CACNG4) Ion channels [BR:lav04040]  Voltage-gated cation channels   Calcium channel, voltage-gated (Cav)    100664775 (CACNG4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PMP22_Claudin Claudin_2 AA_permease_2 Patatin DUF2269 Motif Other DBs NCBI-GeneID:  100664775 NCBI-ProteinID:  XP_003417258 LinkDB All DBs Position Unknown AA seq 348 aa AA seqDB search MNTYSSPAASVPTSLPATAPELNTEQGLQCSRVLSHKLRWSCLHSTITTPRHRLHAEACL PSLASAESALATFCPRRKGTPAAPLFHKCQNSHVRIYKGHCFRINHFPEDNDYDHDSSEY LLRIVRASSVFPILSTILLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVY ISSNTGDPSDKRDEDKKNHYNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKR EFLKASSSSPYARMPSYRYRRRRSRSSSRSTEASPSRDTSPVGLKIAGAIPMGELSMYTL TREPLKVTTAASYSPDQEASFLQVHDFLQQDLKEGFHISMLNRRTTPV NT seq 1047 nt NT seq  +upstreamnt  +downstreamnt atgaacacctactcctctcctgctgccagtgtgcccacgtcactacctgccacagcacct gaactaaacacagagcaggggctgcagtgctcccgggtgctgtcccacaagctccgctgg agctgtctgcacagcaccatcaccaccccgaggcacaggctgcatgcggaagcctgcctg cccagcctcgccagcgcggagagcgccttagccactttctgcccccgaagaaagggcacc cctgctgcccctctattccacaagtgtcagaatagccacgtgcggatctataaagggcac tgcttccggatcaatcacttccccgaggacaatgattacgaccatgacagctccgagtac ctccttcgcatcgtgcgtgcctccagcgtcttccccatcctcagcaccatccttctcctg cttggggggctctgcatcggcgccgggaggatctacagccgcaagaacaacatcgtcctc agtgccggcatcctcttcgtggctgcaggcctcagcaacatcattggcattatcgtatac atttccagcaacacaggtgacccaagtgacaagcgagatgaagacaagaaaaatcactac aactacggctggtcattctactttggagccctgtcttttattgtggctgagaccgtgggc gtcctggcagtgaacatttacattgagaaaaataaagagttgagatttaagaccaaacgg gagttccttaaggcctcttcctcttctccttacgccaggatgccaagctacaggtaccgg cgacggcgctcacgctccagctcacggtccactgaggcctcgccctccagggacacgtcg cccgtgggcctgaagatcgcaggggccatccccatgggcgagctgtccatgtacacgctg accagggagcccctcaaggtgaccactgctgccagctacagccccgaccaggaggccagc ttcctgcaggtgcacgactttctccagcaggacctgaaggaaggtttccacatcagcatg ctgaaccggcggacaacccccgtgtga

Loxodonta africana (African savanna elephant): 100665821 Help Entry 100665821         CDS       T04351                                  Gene name CACNG5 Definition (RefSeq) voltage-dependent calcium channel gamma-5 subunit isoform X2   KO K04870   voltage-dependent calcium channel gamma-5 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04010   MAPK signaling pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav04921   Oxytocin signaling pathway lav05410   Hypertrophic cardiomyopathy lav05412   Arrhythmogenic right ventricular cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100665821 (CACNG5)  09150 Organismal Systems   09152 Endocrine system    04921 Oxytocin signaling pathway     100665821 (CACNG5)   09153 Circulatory system    04260 Cardiac muscle contraction     100665821 (CACNG5)    04261 Adrenergic signaling in cardiomyocytes     100665821 (CACNG5)  09160 Human Diseases   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100665821 (CACNG5)    05412 Arrhythmogenic right ventricular cardiomyopathy     100665821 (CACNG5)    05414 Dilated cardiomyopathy     100665821 (CACNG5)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:lav04040]     100665821 (CACNG5) Ion channels [BR:lav04040]  Voltage-gated cation channels   Calcium channel, voltage-gated (Cav)    100665821 (CACNG5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PMP22_Claudin Claudin_2 SUR7 COPI_assoc DUF716 Serinc DHHC Motif Other DBs NCBI-GeneID:  100665821 NCBI-ProteinID:  XP_003417344 UniProt:  G3UA92 LinkDB All DBs Position Unknown AA seq 275 aa AA seqDB search MSGCGRKALTLLSSIFAVCSLGLLGIAVSTDYWLYLEEGVILPQNQSTEIKMSLHSGLWR VCFLAGEERGRCFTIEYMMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILSNI GHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDSETYFNYKYGWSFA FAAISFLLTESAGVMSVYLFMKRYTAEDMYRPHPGFYRPRLSNCSDYSGQFLHPDAWVRG RSPSDISSDASLQMNSNYPALLKCPDYDQMSSSPC NT seq 828 nt NT seq  +upstreamnt  +downstreamnt atgagtggctgcgggaggaaggccctgaccctgctgagcagcatctttgccgtgtgcagc ctgggtctcctggggatcgctgtcagcactgactactggctgtacctggaggagggtgta atcctgccgcagaaccagagcacagagatcaagatgtccctgcactccggcctctggcga gtctgctttctggcaggtgaagagcggggccgctgcttcaccatagaatacatgatgccc atgaacacccagctgacgtccgagtccacggtcaacgttctaaaaatgattcgctctgcc acgccgttccctctggtcagccttttcttcatgttcattgggtttatcttgagcaatatt ggacacatccgtccccacaggacaatactggcctttgtctctggcatcttctttatcctc tcgggcctctctctcgtggtcggcctggtgctctacatctccagcatcaatgacgagatg ctcaacaggaccaaggactcagagacctatttcaactacaaatacgggtggtcgtttgcc ttcgctgccatctccttccttttaacagagagtgctggggtgatgtccgtgtacctgttc atgaagcggtataccgccgaggacatgtacaggcctcaccccggcttctaccgcccgcgt ctgagcaactgctccgattactcgggccagtttctacacccggacgcctgggtccggggc cgcagcccctccgacatctccagcgacgcctccctacagatgaacagcaactatccagcc ttgctcaagtgccccgactacgaccagatgtcatcttctccctgctga

Loxodonta africana (African savanna elephant): 100666105 Help Entry 100666105         CDS       T04351                                  Gene name CACNG1 Definition (RefSeq) voltage-dependent calcium channel gamma-1 subunit   KO K04866   voltage-dependent calcium channel gamma-1 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04010   MAPK signaling pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav04921   Oxytocin signaling pathway lav05410   Hypertrophic cardiomyopathy lav05412   Arrhythmogenic right ventricular cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100666105 (CACNG1)  09150 Organismal Systems   09152 Endocrine system    04921 Oxytocin signaling pathway     100666105 (CACNG1)   09153 Circulatory system    04260 Cardiac muscle contraction     100666105 (CACNG1)    04261 Adrenergic signaling in cardiomyocytes     100666105 (CACNG1)  09160 Human Diseases   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100666105 (CACNG1)    05412 Arrhythmogenic right ventricular cardiomyopathy     100666105 (CACNG1)    05414 Dilated cardiomyopathy     100666105 (CACNG1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:lav04040]     100666105 (CACNG1) Ion channels [BR:lav04040]  Voltage-gated cation channels   Calcium channel, voltage-gated (Cav)    100666105 (CACNG1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Claudin_2 PMP22_Claudin Clc-like UL45 LapA_dom DUF981 Claudin_3 DUF805 FA_desaturase Motif Other DBs NCBI-GeneID:  100666105 NCBI-ProteinID:  XP_003417345 UniProt:  G3TL37 LinkDB All DBs Position Unknown AA seq 224 aa AA seqDB search MSQTKTLKVRVTLFFILVGVVLAMVAVVTDHWAVLSPHLAHQNSTCEMAHFGLWRICTKR IVLGDSKDKSCRTITLSGEKNCSYFRHFNPGETSEIFEVTTQKEYSISAAAIAIFSLGFI IIGTIFLLFSFREKRDYLLRPASMFYAFAGLCIIVSVEVMRQSVKRMIDSEDTVWIEYYY SWSFACACTAFVLLFLGGLTLLLFSLPPMPQNPWESCMDAEPEH NT seq 675 nt NT seq  +upstreamnt  +downstreamnt atgtcccagaccaaaaccctgaaggtccgtgtgaccctcttcttcatcctggtaggtgtt gtgctggccatggtggctgtggtgaccgaccactgggccgtgctcagcccccatttggct caccagaacagtacctgtgagatggcccacttcggcctctggcggatttgtaccaaacgc atcgtgctgggtgacagcaaggacaagagctgcagaaccatcaccctgtccggggagaaa aactgctcctacttcaggcattttaaccccggtgagacctcggagatcttcgaagtcacc actcagaaagagtacagcatctcagcggctgccattgccatcttcagccttggtttcatc atcataggcaccatcttcctcctcttttccttccgggagaagagggattacctgctgagg ccggcatccatgttctacgccttcgcaggtctctgcatcattgtctcagtggaggtcatg cggcagtcagtgaaacgcatgattgacagcgaggacaccgtctggatcgaatactattac tcctggtccttcgcctgcgcctgcaccgcctttgtcctcctcttcctgggaggcctcact cttctgctcttctccctgcctccaatgccccagaacccgtgggagtcctgcatggatgct gagcctgagcattag

Loxodonta africana (African savanna elephant): 100667110 Help Entry 100667110         CDS       T04351                                  Gene name CACNA2D2 Definition (RefSeq) voltage-dependent calcium channel subunit alpha-2/delta-2   KO K04859   voltage-dependent calcium channel alpha-2/delta-2 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04010   MAPK signaling pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav04921   Oxytocin signaling pathway lav05410   Hypertrophic cardiomyopathy lav05412   Arrhythmogenic right ventricular cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100667110 (CACNA2D2)  09150 Organismal Systems   09152 Endocrine system    04921 Oxytocin signaling pathway     100667110 (CACNA2D2)   09153 Circulatory system    04260 Cardiac muscle contraction     100667110 (CACNA2D2)    04261 Adrenergic signaling in cardiomyocytes     100667110 (CACNA2D2)  09160 Human Diseases   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100667110 (CACNA2D2)    05412 Arrhythmogenic right ventricular cardiomyopathy     100667110 (CACNA2D2)    05414 Dilated cardiomyopathy     100667110 (CACNA2D2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:lav04040]     100667110 (CACNA2D2) Ion channels [BR:lav04040]  Voltage-gated cation channels   Calcium channel, voltage-gated (Cav)    100667110 (CACNA2D2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  VGCC_alpha2 VWA_N VWA VWA_3 VWA_2 dCache_1 dCache_2 VWA_CoxE DUF5610 Ntox50 Motif Other DBs NCBI-GeneID:  100667110 NCBI-ProteinID:  XP_023403428 LinkDB All DBs Position Unknown AA seq 1172 aa AA seqDB search MAVPARTCGASRPGPARTPHPWPGPGVQRPAPGTPRPLVLLLLSPLLLLPLLAAPGASAY SFPQQHTMQHWARRLEQEIDGVMRIFGGVQQLREIYKDNRNLFEVQENEPQKLVEKVAGD IESLLDRKVQALKRLADAAENFQKAHRWQDNIKEEDIMYYDAKADTELDDPESEDMERGS KASTLRLDFVEDPNFKNKVNYSYTAVQIPTDIYKGSTVILNELNWTEALENVFIENRRQD PTLLWQVFGSATGVTRYYPATPWRAPKKIDLYDVRRRPWYIQGASSPKDMVIIVDVSGSV SGLTLKLMKTSVCEMLDTLSDDDYVNVASFNEKAQPVSCFTHLVQANVRNKKVFKEAVQG MVAKGTTGYKAGFEYAFDQLQNSNITRANCNKMIMMFTDGGEDRVQDVFEKYNWPNRTVR VFTFSVGQHNYDVTPLQWMACANKGYYFEIPSIGAIRINTQEYLDVLGRPMVLAGKEAKQ VQWTNVYEDALGLGLVVTGTLPVFNLTQDGPGEKKNQLILGVMGIDVALSDIKRLTPNYT LGANGYVFAIDLNGYVLLHPNLKPQTTNFREPVTLDFLDAELEDENKEEIRRSMIDGNKG HKQIRTLVKSLDERYIDEVMRNYTWVPIRSTNYSLGLVLPPYSTFYLQANLSDQILQVKY FEFLLPSSFESEGHVFIAPREYCKDLNASDNNTEFLKNFIELMEKVTPDSKQCNNFLLHN LILDTGITQQLVERVWRDQDLNTYSLLAVFAATDGGITRVFPNKAAEDWTENPEPFNSSF YRRSLDNHGYVFKPPHQDTLLRPLELENDTVGVLVSTAVELSLGGRTLRPAVVGVKLDLE AWAEKFKVLASNRTHQDQPQKQCGPSSHCEMDCEVNNEDLLCVLIDDGGFLVLSNQNHQW DQVKVRKRVEGEGQGSNLLWVWHCQPVSTTPFRHPQVGRFFSEVDANLMLALYNNSFYAR KESFDYQAACAPQPPGNLGAAPRGVFVPTIADFLNLAWWTSAAAWSLFQQFLYGLIYHSW FQADPAEAEGSPEARESSCVMKQTQYYFGSVNASYNAIIDCGNCSRLFHAQRLTHTNLLF VVAEKPLCSQCEAGRLLQKETHSDGPEQCELVQRPRYRRGPHICFDYNATEDTSDCGRGA SFPPSLSVLVSLQLLLLLGLQPQVQAHASCRL NT seq 3519 nt NT seq  +upstreamnt  +downstreamnt atggcggtgccggctcggacctgcggcgcctcccggcccggcccggcgcggaccccgcac ccctggccaggccccggcgtccagcgcccggcgcccgggaccccgcgcccgctggtgctg ctgctgctgtcgccgctgctgttgctaccgctgctcgccgcccccggtgcctctgcctac agcttcccccagcagcacacgatgcagcattgggcccggcgcctggagcaggagatcgat ggtgtaatgcggatttttgggggcgttcagcagctccgagagatctacaaggacaaccgg aacctgtttgaggtgcaggagaatgaacctcagaagttggtggagaaggtggcgggagac attgagagcctgctggacaggaaggtgcaggccctgaagagattggctgacgctgcggag aacttccagaaagcccaccgctggcaggacaacatcaaggaggaagacatcatgtactat gacgccaaggctgacactgagctggacgaccctgagagtgaggatatggagaggggatca aaggccagcaccttgaggctggactttgtcgaggatccaaacttcaagaacaaggtcaac tattcgtacacagcggtgcagatccctacggacatctacaaaggctccactgtcatcctc aacgagctcaactggacggaggccctggaaaatgtcttcatcgagaaccgcaggcaggac cccacactgctatggcaggtcttcggcagtgccacaggagtcacccgctactatccagcc accccatggcgagcccccaagaagattgacctgtacgacgtccgaaggagaccctggtac atccagggggcctcgtcacccaaggacatggtcatcatcgtggatgtgagcggcagcgtg agcggcctgactctgaagctgatgaagacatctgtctgtgagatgctggatacactgtcc gatgatgactatgtgaacgtggcctcgttcaacgagaaggcacagcctgtgtcatgcttc acgcacctggtgcaggccaatgtgcgtaacaagaaggtgttcaaggaagctgtgcagggc atggtggccaagggcaccacaggctacaaggccggctttgagtatgctttcgaccagctg cagaattccaacattactcgtgccaactgcaacaagatgatcatgatgttcacggatggt ggtgaggaccgagtgcaggacgtctttgagaagtacaactggcccaaccggacggtacgc gtgttcacattttccgtggggcagcacaactatgatgtcacgcccctacagtggatggcc tgtgccaacaaaggttactattttgagatcccttccatcggtgccatccgcatcaacacg caggaatatctggacgtgttgggcaggcccatggtgctggcaggcaaagaggccaagcag gtgcaatggaccaacgtgtatgaggatgcgctggggctaggattggtagtgacagggacc ctccccgttttcaacctgacacaggatggccctggggaaaagaagaaccagctgatcctc ggcgtgatgggcatcgatgtggctctaagtgacatcaagaggctgactcccaactataca cttggagccaatggctacgtgtttgccattgacctgaacggctatgtgctgctacacccc aacctcaagccccagaccactaacttccgggagcctgtgaccctggacttcctggatgca gagctggaggatgagaacaaggaggagatccgtagaagcatgattgatggcaacaaaggc cacaagcagatcagaacgctggtcaagtccctggatgagaggtacatagacgaggtgatg cggaactacacctgggttcccataaggagcaccaactacagcctagggctggtgctcccg ccatacagcaccttctacctccaagccaacctcagtgatcagatcctgcaggtcaagtat tttgaattcctgctccccagcagctttgagtctgaaggacatgttttcattgctcccaga gagtattgcaaggacctgaacgcctctgacaacaacaccgagttcctgaaaaacttcatt gagctcatggagaaggtgactccagactccaagcagtgcaacaacttccttctgcacaac ctgatcttggacacgggcatcacacaacagctggtggagcgtgtatggcgggaccaggac ctcaacacgtacagcctgctggcagtgttcgctgccactgatggtggcatcacccgtgtc ttccccaacaaggcagctgaggactggacagagaaccccgaacccttcaattccagcttc taccgccgcagcctggataaccacggctatgtcttcaagcccccacaccaggataccctg ttaaggccactggagctggagaacgacactgttggtgtcctggtcagcacagctgtggaa ctcagcctgggagggcgcacactgaggccagcagtggtgggcgtcaagctggacctggag gcctgggctgaaaagttcaaggtgctagccagcaatcgcactcaccaggaccaacctcag aagcagtgcggccccagcagccactgtgagatggattgcgaagttaacaatgaggacctg ctctgtgttctcattgatgatgggggattcctggtgctgtcgaaccagaaccatcagtgg gaccaggtgaaagtcaggaaaagggtggaaggagagggacaaggctcaaaccttctgtgg gtgtggcactgccagcctgtgtccacaacccccttccggcatccccaggtgggcaggttc ttcagtgaagtggatgccaacctgatgctggcactctacaataattccttctacgcccgc aaggagtccttcgactatcaggcagcctgtgcaccccagcccccagggaacctgggggct gcgccgcggggcgtctttgtgcccaccattgcagacttccttaacctggcctggtggacc tcggctgcggcctggtccttgttccagcagtttctctatggcctcatctaccacagctgg ttccaggcagacccggcggaggccgaggggagccccgaggcgcgtgagagcagctgcgtc atgaaacagacccagtactacttcggctcggtgaacgcctcctacaacgccatcatcgac tgcggaaactgctccaggctgttccacgcgcagagactgacccacaccaaccttctcttc gtggtggccgagaagccgctgtgcagccagtgtgaagctggccggctgctgcaaaaggag acacactcggacggcccggagcagtgtgagctggtgcagagaccgcgataccggagaggc ccacacatctgcttcgactacaacgcgacggaagatacctcagactgtggccgcggagcc tccttcccgccgtcgctgagcgtcctggtctccctgcagctgctgctccttctgggcctg cagccccaagttcaggcccacgcctcatgtcgcctttga

Loxodonta africana (African savanna elephant): 100672020 Help Entry 100672020         CDS       T04351                                  Gene name CACNG7 Definition (RefSeq) voltage-dependent calcium channel gamma-7 subunit   KO K04872   voltage-dependent calcium channel gamma-7 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04010   MAPK signaling pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav04921   Oxytocin signaling pathway lav05410   Hypertrophic cardiomyopathy lav05412   Arrhythmogenic right ventricular cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100672020 (CACNG7)  09150 Organismal Systems   09152 Endocrine system    04921 Oxytocin signaling pathway     100672020 (CACNG7)   09153 Circulatory system    04260 Cardiac muscle contraction     100672020 (CACNG7)    04261 Adrenergic signaling in cardiomyocytes     100672020 (CACNG7)  09160 Human Diseases   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100672020 (CACNG7)    05412 Arrhythmogenic right ventricular cardiomyopathy     100672020 (CACNG7)    05414 Dilated cardiomyopathy     100672020 (CACNG7)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:lav04040]     100672020 (CACNG7) Ion channels [BR:lav04040]  Voltage-gated cation channels   Calcium channel, voltage-gated (Cav)    100672020 (CACNG7) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Claudin_2 PMP22_Claudin DUF716 Amastin L_HMGIC_fpl Claudin_3 Serinc DUF4064 Motif Other DBs NCBI-GeneID:  100672020 NCBI-ProteinID:  XP_003406901 UniProt:  G3U584 LinkDB All DBs Position Unknown AA seq 275 aa AA seqDB search MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWR VCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNI GHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFA FAASSFLLKERAGVMSVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQPEAWRRG RSPSDISSDVSIQMTQNYPPAIKYPDHLHISTSPC NT seq 828 nt NT seq  +upstreamnt  +downstreamnt atgagtcactgtagcagccgcgccctgaccctgctgagcagtgtgtttggtgcctgcggc ttgctccttgtgggcattgcggtcagcaccgactactggctatacatggaggagggtaca gtgctgccacagaaccagaccaccgaggtcaagatggcactacacgctggcctctggaga gtctgcttctttgcaggtcgtgagaagggtcgctgcgtggcctcggaatatttcctggaa ccggagatcaatttggtgacggaaaacacggagaatattctgaagacagtgcgcacggct acccccttccccatggtcagcctcttccttgtgttcactgccttcgtcatcagcaacatc ggccacatccgcccacagaggaccattctggccttcgtttctggcatctttttcatcctg tcgggcctctccttggtggtgggattggttctctacatctccagcatcaatgacgaggtt atgaacaggcccagcagctctgagcagtattttcactatcgctacgggtggtcgtttgcc ttcgctgcttcctccttcctactcaaagagagagccggcgtgatgtcagtgtacctgttc accaagcgctacgcggaggaggagatgtaccgtccgcacccggccttctaccgcccgcgt ctcagcgactgctccgactactcgggccagtttctgcagcctgaggcgtggcgccgcggc cgcagcccctctgacatctccagcgacgtctccatccagatgacgcagaactaccctccc gccatcaagtaccccgaccacctgcacatctccacctcgccctgctga

Loxodonta africana (African savanna elephant): 100672366 Help Entry 100672366         CDS       T04351                                  Gene name CACNG3 Definition (RefSeq) voltage-dependent calcium channel gamma-3 subunit   KO K04868   voltage-dependent calcium channel gamma-3 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04010   MAPK signaling pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav04921   Oxytocin signaling pathway lav05410   Hypertrophic cardiomyopathy lav05412   Arrhythmogenic right ventricular cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100672366 (CACNG3)  09150 Organismal Systems   09152 Endocrine system    04921 Oxytocin signaling pathway     100672366 (CACNG3)   09153 Circulatory system    04260 Cardiac muscle contraction     100672366 (CACNG3)    04261 Adrenergic signaling in cardiomyocytes     100672366 (CACNG3)  09160 Human Diseases   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100672366 (CACNG3)    05412 Arrhythmogenic right ventricular cardiomyopathy     100672366 (CACNG3)    05414 Dilated cardiomyopathy     100672366 (CACNG3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:lav04040]     100672366 (CACNG3) Ion channels [BR:lav04040]  Voltage-gated cation channels   Calcium channel, voltage-gated (Cav)    100672366 (CACNG3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PMP22_Claudin Claudin_2 Motif Other DBs NCBI-GeneID:  100672366 NCBI-ProteinID:  XP_003418869 UniProt:  G3TF52 LinkDB All DBs Position Unknown AA seq 315 aa AA seqDB search MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYWLYSRGVCRTKSTSDNETSRKNEEVMTH SGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFFGGL CVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQRDSKKSYSYGWSFY FGAFSFIIAEIVGVVAVHIYIEKHQQLRAKSHSELLKKSTFARLPPYRYRFRRRSSSRST EPRSRDLSPISKGFHTIPSTDISMFTLSRDPSKITMGTLLNSDRDHAFLQFHNSTPKEFK ESLHNNPANRRTTPV NT seq 948 nt NT seq  +upstreamnt  +downstreamnt atgaggatgtgtgacagaggtatccagatgttgatcactactgtgggagcctttgcagct tttagtttaatgaccattgcagtgggcactgactactggttatattccagaggtgtgtgc aggactaaatctacaagtgataatgaaaccagcaggaagaatgaagaagtaatgacccat tccgggctgtggaggacctgctgcctagaaggggctttccgaggagtgtgcaagaaaatt gatcacttccctgaagatgctgactacgaacaggatacagcagaatatttactgagggct gtgagggcctccagtgtcttccccatcctcagcgtcacactgctgttctttggtgggcta tgcgtggcagccagtgagttccatcgcagcaggcacaacgtcattctcagcgcgggcatc ttttttgtctctgcagggttaagcaacatcatcggcatcattgtttatatatcagcaaat gctggagaccccgggcagcgtgactccaaaaaaagctactcctatggctggtccttctat tttggagccttctctttcatcatcgcggagattgtgggggtggtcgctgtacacatctac attgaaaaacatcagcagttacgtgccaaatcccactcggagctcctgaagaaatctact tttgcccgccttccaccctataggtatagattccggaggcggtcaagctcccgctccaca gagcccagatcccgagacctgtcccccatcagcaaaggtttccacaccatcccttccacc gacatctcaatgtttaccctctcccgggacccctcaaagatcaccatggggaccctcctc aactccgaccgggaccatgcttttctacagttccacaactccactcccaaagagttcaaa gagtcgctgcataataatccggccaacaggcgcaccacgcccgtctga

Loxodonta africana (African savanna elephant): 100673089 Help Entry 100673089         CDS       T04351                                  Gene name CACNA1S Definition (RefSeq) LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1S   KO K04857   voltage-dependent calcium channel L type alpha-1S Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04010   MAPK signaling pathway lav04020   Calcium signaling pathway lav04022   cGMP-PKG signaling pathway lav04024   cAMP signaling pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav04270   Vascular smooth muscle contraction lav04723   Retrograde endocannabinoid signaling lav04725   Cholinergic synapse lav04726   Serotonergic synapse lav04727   GABAergic synapse lav04911   Insulin secretion lav04912   GnRH signaling pathway lav04921   Oxytocin signaling pathway lav04924   Renin secretion lav04925   Aldosterone synthesis and secretion lav04927   Cortisol synthesis and secretion lav04929   GnRH secretion lav04934   Cushing syndrome lav04935   Growth hormone synthesis, secretion and action lav05010   Alzheimer disease lav05020   Prion disease lav05022   Pathways of neurodegeneration - multiple diseases lav05410   Hypertrophic cardiomyopathy lav05412   Arrhythmogenic right ventricular cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100673089 (CACNA1S)    04020 Calcium signaling pathway     100673089 (CACNA1S)    04024 cAMP signaling pathway     100673089 (CACNA1S)    04022 cGMP-PKG signaling pathway     100673089 (CACNA1S)  09150 Organismal Systems   09152 Endocrine system    04911 Insulin secretion     100673089 (CACNA1S)    04929 GnRH secretion     100673089 (CACNA1S)    04912 GnRH signaling pathway     100673089 (CACNA1S)    04921 Oxytocin signaling pathway     100673089 (CACNA1S)    04935 Growth hormone synthesis, secretion and action     100673089 (CACNA1S)    04924 Renin secretion     100673089 (CACNA1S)    04925 Aldosterone synthesis and secretion     100673089 (CACNA1S)    04927 Cortisol synthesis and secretion     100673089 (CACNA1S)   09153 Circulatory system    04260 Cardiac muscle contraction     100673089 (CACNA1S)    04261 Adrenergic signaling in cardiomyocytes     100673089 (CACNA1S)    04270 Vascular smooth muscle contraction     100673089 (CACNA1S)   09156 Nervous system    04727 GABAergic synapse     100673089 (CACNA1S)    04725 Cholinergic synapse     100673089 (CACNA1S)    04726 Serotonergic synapse     100673089 (CACNA1S)    04723 Retrograde endocannabinoid signaling     100673089 (CACNA1S)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     100673089 (CACNA1S)    05020 Prion disease     100673089 (CACNA1S)    05022 Pathways of neurodegeneration - multiple diseases     100673089 (CACNA1S)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100673089 (CACNA1S)    05412 Arrhythmogenic right ventricular cardiomyopathy     100673089 (CACNA1S)    05414 Dilated cardiomyopathy     100673089 (CACNA1S)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100673089 (CACNA1S)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:lav04040]     100673089 (CACNA1S) Ion channels [BR:lav04040]  Voltage-gated cation channels   Calcium channel, voltage-gated (Cav)    100673089 (CACNA1S) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ion_trans GPHH Ca_chan_IQ PKD_channel Motif Other DBs NCBI-GeneID:  100673089 NCBI-ProteinID:  XP_023404020 LinkDB All DBs Position Unknown AA seq 1719 aa AA seqDB search MEPSSPQDEGLKKKQPKKPVPENLPRPPRALFCLTLENPLRKACISIVEWKLFEMIILLT IFANCVALAVYLPMPEDDNNSLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS GWNVLDFIIVFLGVFTVILEQVNVIQSNTTPLGSKGAGLDVKALRAFRVLRPLRLVSGVP SLQVVLNSIFQAMLPLFHIALLVLFMLIIYAIIGLELFKGKMHKTCYFIGTDIMATVENE KPSPCSRSGLGRRCTINGSECRGSWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW VNDAIGNEWPWIYFLTLILLGSFFILNLVLGILSGEFTKEREKAKSRGTFQKLREKQQLE EDLRGYMSWITQGEVMDVEDLREGKLSLVEGGSDTESLYEIEGLNKIIQFVRHWRRWNRI LRWKCHDVVKSRVFYWLVILIVALNTLSIASEHHNQPLYLTYLQDVANRVLLALFTIEML MKMYGLGLHQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRLFKITK YWTSLSNLVASLLNSVRSIASLLLLLFLFITIFALLGMQLFGGRYDFEDVEVRRSNFDNF PQAIISVFQVLTGEDWTSMMYNGIMAYGGPSYPGMLVSIYFIILFVCGNYILLNVFLAIA VDNLAEAESLTSAQKAKAEEKKRRKMSKGLPDKSEEEKSILAKKLEQKPKGEGIPTTAKL KIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFF IFSPTNKIRVLCHRIVNATWVTNFILLFILLSSAALAAEDPIRVKSVRNQILEYFDIVFT SVFTVEIILKMTTFGVFLHKGSFCRNYFNILDLVVVAVSLISMGLESSTISVVKILRVLR VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFIFACIGVQLFKGKFFSCNDL SKMTEEECRGYYYVYKDGDPTQMELRPRQWIHNEFHFDNVLSAMMSLFTVSTFEGWPQLL YKAIDSNKEDMGPIYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE LNKNQRQCVQYALKARPLRCYIPKNPYQYKVWYFVTSSYFEYLMFALIMLNTICLGMQHY NQSEQMNHISDILNVAFTIIFTLEMILKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS EIDTFLASSGGLYCLGGGCGNVDPDESGRISSAFFRLFRVLGVIKLVGGGEGVRTLLGTF IKSFQGALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRC ATGEAWQEILLACSYGKLCDPESDYAPGEEYTCGTNFAYYYFISFYMLCAFLIINLFVAV IMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFC PHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWK RTSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTVQIQAGL RTIEEEAAPEIHRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLP PVMANQRPLQFAEIEMEELESPVFLEDFPQHPSTNSLARANTNNANANTACGNSNHSNSH VFSSVHYEREFPGEREVLAAREGALGQPHRAPGQSLLCT NT seq 5160 nt NT seq  +upstreamnt  +downstreamnt atggagccctcctcgccccaggatgagggcctgaagaagaaacagcccaagaagcctgtt cctgagaatctgccaaggccaccccgtgccttgttctgcctgaccctagagaaccccctg agaaaggcctgcatcagcatcgtggaatggaaactctttgagatgatcatcttgctcacc atctttgccaactgtgtggccctggccgtgtacttgcccatgcctgaagatgacaacaac tctctgaacctgggcctggagaagcttgagtatttcttcctcatcgtgttctcaattgaa gctgccatgaagatcatcgcctatggcttcctattccaccaggatgcctacctgcgcagc ggctggaacgtgctggacttcatcattgtcttcctgggggtcttcactgtgattctggag caggttaacgtcatccaaagcaacacaacccctttgggcagcaaaggagctggcttggac gtcaaggccctgagagccttccgtgtgctcagacccctccggctggtgtcgggggtgccc agcctgcaggtggtcctcaactccatcttccaggccatgctccccctgttccacattgcc ctgcttgttctcttcatgctcatcatctatgccatcattgggttggaacttttcaagggc aagatgcacaagacctgctacttcattggaacagatatcatggccacagtagagaatgag aagccctcgccctgctccaggtcgggcttggggcgccggtgtaccatcaacggcagcgag tgccggggcagctggccaggacccaaccacggcatcacccacttcgacaactttggcttc tccatgctcaccgtgtaccagtgcatcaccatggaggggtggaccgatgtgctttactgg gtcaatgatgccatcgggaacgagtggccctggatctactttctcaccctcattctgctg ggctccttcttcattctcaacctggtgctgggtattctaagtggggaattcaccaaggag cgggagaaggccaaatccaggggaaccttccagaagctccgggagaagcagcagctggag gaggaccttcgaggctacatgagctggattacgcagggcgaggtcatggacgtggaggat ttaagagaagggaagctgtctttggttgaaggtggctccgacacagagagcctgtatgaa attgagggcttgaacaaaatcatccagtttgtccgacactggaggcgctggaaccgcatc ttacgctggaagtgccatgatgtggtgaagtccagggtcttctattggctggtgatcctg atcgttgccctcaacaccctgtccatcgcctcagagcaccataaccagcccctatatttg acctatttgcaagacgttgccaaccgggtgctactggctctcttcaccatcgagatgctg atgaagatgtatgggctgggcttacaccagtacttcatgtccatcttcaaccgctttgac tgcttcgtggtgtgcagcggcatcctagagatcctgctggtggagtcgggcgccatgaca ccgctgggcatttctgtgcttcgctgcatccgcctcctgaggctgttcaagatcaccaag tattggacatcactgagcaacctggtcgcatccctgctcaactccgtccgctccattgcc tccctgctgctgctgctcttcctcttcatcaccatctttgctttgctgggcatgcagctc tttgggggcaggtacgacttcgaggacgtggaggtgcggcgcagcaacttcgacaacttc ccccaagccatcatcagcgtcttccaggtcctgacaggggaggactggacttcgatgatg tacaacgggatcatggcctacggcgggccatcctaccccggcatgcttgtgtccatttat ttcatcatccttttcgtctgtggcaactacatcttgctcaacgtcttcctggccattgct gtggacaacctggccgaggcggagagcctgacttccgcccagaaggccaaggctgaggag aagaaacgcaggaagatgtccaagggtctcccagacaagtcagaggaggagaagtcaatt ttggccaagaagctggaacagaaacccaagggtgagggcatccccacaactgccaagctg aaaatcgatgagtttgaatctaacgttaatgaggtgaaggacccttacccctcggctgac ttcccaggggatgatgaggaagatgagcccgagatcccagtgagcccccgaccacgtccc ctggctgagctgcagctgaaggagaaggcagtgcccattccagaagccagctccttcttc atcttcagccccaccaataagatccgtgtcctgtgtcaccgcattgtcaacgccacctgg gtcaccaacttcatcttgctcttcatcctgcttagcagtgctgccctggcggctgaggac cccatccgggtgaaatctgtcaggaaccagatccttgagtattttgacatcgtgttcacc tctgttttcactgtggagattatcctcaagatgacaaccttcggtgtcttcctgcacaag ggctccttttgccggaactatttcaacatcctggacctggtggtagtggccgtgtccctc atctccatgggacttgagtccagcaccatctctgtggtaaagatcctgagggtgctgagg gtgctccgacccctccgagccatcaacagagccaaagggttgaagcacgtggtgcaatgt gtgttcgtggccatccgcaccatcgggaacatcgtcctggtcaccaccctcctgcagttc attttcgcctgcatcggcgtccagctcttcaagggaaagttcttcagctgcaatgactta tccaagatgacagaagaggagtgcaggggctactactatgtgtacaaagatggggacccc acgcagatggagctgcgtccccggcagtggatacacaacgaattccactttgacaacgtg ctctcggccatgatgtcactcttcacagtctccaccttcgagggatggcctcagctactg tacaaggccatagattcaaacaaggaggacatgggccccatctacaacaaccgagtggag atggccatcttcttcatcatctacatcatcctcattgccttcttcatgatgaacatcttt gtgggcttcgttattgtcaccttccaggagcagggggagactgagtacaagaattgtgag ctgaacaagaaccagcgccagtgtgtacagtatgccctgaaagcccgcccactgaggtgc tacatccccaaaaacccataccagtacaaggtgtggtacttcgtcacatcctcctacttc gaatacctgatgtttgccctcatcatgctcaacaccatctgcctgggcatgcagcactac aatcaatcagagcagatgaatcacatctcagatatcctcaacgtggccttcaccatcatc ttcaccttggagatgatcctcaagctcatggcattcaaggccaggggctattttggagac ccctggaatgtgtttgacttcttgatcgtcatcggcagcatcattgacgtcatccttagt gagattgacactttcctggcctccagcgggggactgtattgcctgggtggaggctgcggg aacgttgacccagacgagagtggccgcatctccagcgccttcttccgcctgtttcgggtc ttgggggtgatcaagctggtgggggggggagagggggtgcgcaccctgctggggaccttc atcaagtccttccagggggccctgccttacgtggccctgctcattgttatgctcttcttc atctacgctgtcatcggcatgcagatgttcgggaagatcgccatggtcgacgggacgcaa ataaaccggaacaacaacttccagaccttcccacaagctgtattgcttctcttcaggtgt gcaacaggagaggcctggcaggagatcctgctggcctgcagctacgggaagttgtgcgac cccgagtcagactacgcccccggtgaggagtacacgtgtggcaccaacttcgcctattac tacttcatcagcttctacatgctctgcgccttcctgatcatcaacctctttgtggctgtc atcatggataactttgactacctcacacgggactggtccatcctgggccctcaccacctg gatgaattcaaggcaatctgggcagagtacgacccggaggcaaaggggcgcatcaaacac ctggacgtggtgaccctgctgagacggatccagccccctctgggctttgggaagttctgc ccccaccgggtggcatgtaagcggctggtgggcatgaacatgcccctgaacagcgacgga acggtcaccttcaacgccacgcttttcgcccttgtccgcacagcactcaagatcaagacg gaaggtaactttgagcaggccaatgaggagctgagggccatcatcaagaagatctggaag agaaccagcatgaagctcctggaccaagtcattcctccaataggagatgatgaggtgact gtgggaaagttctatgccacgttccttatccaagagcacttccggaagttcatgaagcgc caggaggagtattatgggtatcgaccaaagaaggacactgtacagatacaggctggactt cgcaccattgaggaagaggcagcccctgagatccaccgcaccatctcaggagacctgaca gctgaggaggagttggagagagccatggtggaggctgcgatggaggaggggatattccga aggacaggaggcctgtttgggcaggtagacaacttcctggaaaggaccaactccctgccc cctgtcatggccaaccagagacccctccagtttgctgagatagagatggaagaactggaa tcacctgtcttcttggaggacttccctcaacatccaagtaccaactctcttgctcgtgcc aataccaacaatgccaacgccaacactgcgtgcggcaacagcaaccatagcaacagccac gtgttttccagcgttcactatgaaagggagttccctggagagagagaggtgcttgcagcc agagaaggagccctcggacaaccccaccgggccccaggtcagtcccttctgtgcacctga

Loxodonta africana (African savanna elephant): 100673091 Help Entry 100673091         CDS       T04351                                  Gene name CACNB2 Definition (RefSeq) voltage-dependent L-type calcium channel subunit beta-2   KO K04863   voltage-dependent calcium channel beta-2 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04010   MAPK signaling pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav04921   Oxytocin signaling pathway lav05410   Hypertrophic cardiomyopathy lav05412   Arrhythmogenic right ventricular cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100673091 (CACNB2)  09150 Organismal Systems   09152 Endocrine system    04921 Oxytocin signaling pathway     100673091 (CACNB2)   09153 Circulatory system    04260 Cardiac muscle contraction     100673091 (CACNB2)    04261 Adrenergic signaling in cardiomyocytes     100673091 (CACNB2)  09160 Human Diseases   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100673091 (CACNB2)    05412 Arrhythmogenic right ventricular cardiomyopathy     100673091 (CACNB2)    05414 Dilated cardiomyopathy     100673091 (CACNB2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:lav04040]     100673091 (CACNB2) Ion channels [BR:lav04040]  Voltage-gated cation channels   Calcium channel, voltage-gated (Cav)    100673091 (CACNB2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_kin VGCC_beta4Aa_N SH3_1 SH3_2 Motif Other DBs NCBI-GeneID:  100673091 NCBI-ProteinID:  XP_010589188 LinkDB All DBs Position Unknown AA seq 654 aa AA seqDB search MVQSDMSKSPPTAAAAVAQEIQMELLDNAAPAGALGAAAQSYGKGARRKNRFKGSDGSTS SDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVR TNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLE NMRLQHEQRAKQGKFYSSKSGGNSLSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIP ANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMM QKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLGIEDFELAR TLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAA DKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSNLPNPLLSRTLATSTLP ISPTRASNSQGSQGDHRTERSALARSTSQAEEEPCLEPVKKSQHRSSSSAQHHSHRSGTS RGLSRQETFDSETQESRDSAYVEPKEDYSHEHSDHYAPHRDHNHRDEPHASSDHRHRESR HRPRDIDREQDHNECNKQRSRHKSKDRYCDKDGEVISKKRNEAGEWNRDVYIRQ NT seq 1965 nt NT seq  +upstreamnt  +downstreamnt atggtccaaagcgacatgtccaagtcgcctcccacagcggcggcggcggtggcgcaggag atacagatggaactgctggataacgcagctcccgcgggggcgctcggagccgcggcacag tcgtatggaaaaggagctagaaggaaaaacagatttaaaggctctgatggcagcacttca tctgacactacctcaaatagcttcgttcggcagggttcggcagactcctacaccagccgt ccatccgattccgatgtatctttggaggaagaccgggaggcagtgcggagagaagcagag cgacaggcccaggcacagttggaaaaagcaaagacaaagcccgttgcatttgcagttcga acaaacgtcagctacagtgcagcccacgaagatgacgttccagtgccaggcatggccatc tcattcgaagcaaaagattttctgcatgttaaggaaaaatttaacaatgactggtggata ggacgattggttaaagaaggttgtgaaatcggattcattccaagcccagtcaaactagaa aacatgaggcttcagcatgaacagagagccaagcaagggaaattttactccagtaaatca ggaggaaattcattatccagtttgggtgacatagtacctagttccagaaaatctacacct ccatcatctgctatagacatagatgctactggcttagatgcagaagaaaatgatattcca gcaaaccaccgctcccctaaacccagtgcaaacagtgtaacgtcaccccactccaaagag aaaagaatgcccttctttaagaagacagagcacactcctccttatgacgtggtgccttct atgcgaccggtggttctagtgggcccttccctgaaggggtatgaggtcacggatatgatg caaaaagcattgtttgattttttaaaacacagatttgaagggcggatatccatcacaagg gtcactgctgacatctcgcttgccaaacgctcagtattaaacaatccaagtaagcacgca ataatagaaagatccaacacaaggtcaagcttaggaatcgaagattttgagcttgcaaga acattacaactggtagtccttgatgcagacactattaatcacccagctcaactcagtaaa acctctttggcccctattatagtatatgtgaagatttcttctcctaaggtgttacaaagg ttaataaaatctcgagggaaatctcaagctaaacacctcaatgtccagatggtagcagct gataaactggctcagtgtcctccagaattgtttgatgttatcttggatgagaaccagctc gaggatgcctgtgagcaccttgccgactatctggaggcctactggaaggccacccatcct cccagcagcaatctccccaatcctctccttagccgtactttagccacttcaactctgcct attagccccacccgagcctctaattcacagggttctcaaggtgaccataggactgagcgg tctgctcttgcccgttctacttcccaagctgaagaagagccctgcctggaaccagtcaag aaatcccagcatcgttcttcctcctcagcccaacaccacagccatcgcagtggtacaagt cgaggcctctccaggcaagagacttttgactcggaaactcaggagagtcgagactctgcc tatgtagagcccaaggaagattattcgcacgaacactcggaccactatgccccacaccgc gaccataaccaccgagatgagcctcacgcgagcagtgatcacagacacagggaatctcgg caccgccccagggacatagatcgagagcaggaccacaacgagtgcaacaaacaaagaagc cgtcataaatcaaaggatcgttattgtgacaaggatggagaagtaatatccaaaaaacgg aacgaggctggggagtggaacagggatgtttacatccgccagtga

Loxodonta africana (African savanna elephant): 100674649 Help Entry 100674649         CDS       T04351                                  Gene name CACNA1F Definition (RefSeq) LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1F   KO K04853   voltage-dependent calcium channel L type alpha-1F Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04010   MAPK signaling pathway lav04020   Calcium signaling pathway lav04022   cGMP-PKG signaling pathway lav04024   cAMP signaling pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav04270   Vascular smooth muscle contraction lav04723   Retrograde endocannabinoid signaling lav04725   Cholinergic synapse lav04726   Serotonergic synapse lav04727   GABAergic synapse lav04911   Insulin secretion lav04912   GnRH signaling pathway lav04921   Oxytocin signaling pathway lav04924   Renin secretion lav04925   Aldosterone synthesis and secretion lav04927   Cortisol synthesis and secretion lav04929   GnRH secretion lav04934   Cushing syndrome lav04935   Growth hormone synthesis, secretion and action lav05010   Alzheimer disease lav05020   Prion disease lav05022   Pathways of neurodegeneration - multiple diseases lav05410   Hypertrophic cardiomyopathy lav05412   Arrhythmogenic right ventricular cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100674649 (CACNA1F)    04020 Calcium signaling pathway     100674649 (CACNA1F)    04024 cAMP signaling pathway     100674649 (CACNA1F)    04022 cGMP-PKG signaling pathway     100674649 (CACNA1F)  09150 Organismal Systems   09152 Endocrine system    04911 Insulin secretion     100674649 (CACNA1F)    04929 GnRH secretion     100674649 (CACNA1F)    04912 GnRH signaling pathway     100674649 (CACNA1F)    04921 Oxytocin signaling pathway     100674649 (CACNA1F)    04935 Growth hormone synthesis, secretion and action     100674649 (CACNA1F)    04924 Renin secretion     100674649 (CACNA1F)    04925 Aldosterone synthesis and secretion     100674649 (CACNA1F)    04927 Cortisol synthesis and secretion     100674649 (CACNA1F)   09153 Circulatory system    04260 Cardiac muscle contraction     100674649 (CACNA1F)    04261 Adrenergic signaling in cardiomyocytes     100674649 (CACNA1F)    04270 Vascular smooth muscle contraction     100674649 (CACNA1F)   09156 Nervous system    04727 GABAergic synapse     100674649 (CACNA1F)    04725 Cholinergic synapse     100674649 (CACNA1F)    04726 Serotonergic synapse     100674649 (CACNA1F)    04723 Retrograde endocannabinoid signaling     100674649 (CACNA1F)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     100674649 (CACNA1F)    05020 Prion disease     100674649 (CACNA1F)    05022 Pathways of neurodegeneration - multiple diseases     100674649 (CACNA1F)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100674649 (CACNA1F)    05412 Arrhythmogenic right ventricular cardiomyopathy     100674649 (CACNA1F)    05414 Dilated cardiomyopathy     100674649 (CACNA1F)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100674649 (CACNA1F)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:lav04040]     100674649 (CACNA1F) Ion channels [BR:lav04040]  Voltage-gated cation channels   Calcium channel, voltage-gated (Cav)    100674649 (CACNA1F) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ion_trans CAC1F_C Ca_chan_IQ GPHH PKD_channel Motif Other DBs NCBI-GeneID:  100674649 NCBI-ProteinID:  XP_023413606 LinkDB All DBs Position Unknown AA seq 1743 aa AA seqDB search MSEAGTIAQYTCPSLTQFLHTDTTPEPCPANGTGTGQEWGLCPGPPAEGNEICGASGLGT PRRRTQHSKHKMVAVASAQRSPRALFCLTLANPLRRSCISIVEWKPFDILILLTIFANCV ALGVYIPFPEDDSNTANHILEQVEYVFWXFFTMETVLQIVAXGRCSIPALYIRNAPSSSL LADVEAEDDPSPCASSGSGRACMLNQTECRGRWAGPNGGITNFDNFFFAMLTVFQCVTME GWTDVLYWMQDAMGHELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQK LREKQQLEEDLRGYLDWITKAEELDMEDPSTGGNSGSVAIMGQAGHRLPLAKLTNRRLGR LRWFSHSTRSTHSTSSHGGGLARLGQRANEHATNSAPSHLCCRHWASLSNLVASLLNSMK SIASLLLLLFLFIIIFSLLGMQLFGGKFNFDQTHTKRSTFDTFPQALLTVFQILTGEDWN VVMYDGIMAYGGPFFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLASGDAGTAKDKGR EKITEGNLPPENGALVPDGKNEEEEGARNEGAGKXAEPGGEGMEEEEEEEGVGGVEILQE VVPKEKVVPIPEGSAFFCLSQTNPLRKACHTLIHHHIFTNLILVFIILSSVSLAAEDPIR AHSFRNHILGYFDYAFTSIFTVEILLKMTVFGAFLHRGSFCRSWFNLLDLLVVSVSLISF GIHSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFA CIGVQLFKGKFYSCTDEAKHTPQECKGSFLMYPDGDVSRPLVRERLWVNSDFNFDNVLSA MMALFTVSTFEGWPALLYKAIDAHAEDKGPIYNYHVEISVFFIVYIIIIAFFMMNIFVGF VIITFRAQGEQEYQNCELDKNQRQCVEYALKAQPLRRYIPKNPYQYRVWATVNSAAFEYL MFLLILLNTVALVMQHYEQTAPFNYAMDILNMVFTGLFTVEMVLKIIAFKPKHYFADAWN TFDALIVVGSVVDIAVTEVNNGGHLGESSEDSSRISITFFRLFRVMRLVKLLSKGEGVRT LLWTFIKSFQALPYVALLIAMIFFIYAVIGMQMFGKVALQDGTQINRNNNFQTFPQAVLL LFRCATGEAWQEIMLASLPGNRCDPESDFSPGEEFTCGSNFAIAYFISFFMLCAFLIINL FVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPGAKGRIKHLDVVALLRRIQPPLGF GKLCPHRVACKRLVAMNMPLNSDGTVTFNATLFALVRTSLKIKTEGNLEQANQELRTVIK KIWKRMKQKLLDEVIPPPDEEEVTVGKFYATFLIQDYFRKFRRRKEKGLLRTEAPPSTSS VLQAGLRSLQDLGPEIRQALTCDTDEEKEEQGQKGEEEEDEKDPETYQAPIGSQPPSRRS SMISVSLPVGDRLPDSLCLGPSDDYGRTSNSRQASMPQTGFHTCRRSSEPLIFTIPEEGS SKPKGTKGQDKQDKKEEASNLLSYLDEQAETPPRLVLLPPHRPQRYVDGYHAPHRRLLPP TPAGRKPSFTIQCLRRQGSCEDLPIPGTYHRERNSGPSRVQGSWATPPQQGRLLYAPLLL VEEGAAGEGYLGKSSGPLRTFTCLHMPGTHLEPNHGKRSSADSLVEAVLISEGLDLFAQD PHFVALAKQEIADACRLTLDEMDSTASDLLAQGASLLYSEEESILSSFDEEDLGDEMACI HAL NT seq 5232 nt NT seq  +upstreamnt  +downstreamnt atgtcggaggcaggcacgattgcccaatacacttgtccctccctgactcagtttctccac acagacactaccccagagccctgtccagctaatgggacagggactggtcaagaatggggc ctgtgccctgggcccccagccgaagggaatgaaatctgcggggcatcaggtctgggcacc cctaggcgaaggacccagcacagcaagcacaagatggtggcagtggccagtgcacagagg tccccccgggccctcttctgcctcaccctggccaatccgctgcggagatcctgcatcagc attgtggagtggaagcccttcgacatcctcatcctgctgaccatctttgccaactgcgtg gccctgggggtctacatccccttccctgaggatgactccaacactgccaaccacatcctg gagcaggtggagtatgttttttggtgatttttcactatggagactgtgctccagattgtg gcctagggtaggtgctccatcccagcgctctatatccgcaatgccccgagctccagtctc ctcgcagacgtggaggcagaagacgacccatcgccttgtgcgtcttcgggctccgggcgt gcgtgcatgctgaaccagactgagtgccgcgggcgctgggcagggcccaacgggggcatc accaacttcgacaacttcttcttcgccatgttaacggtcttccagtgcgtcaccatggaa ggctggacagacgtgctctactggatgcaggatgccatggggcatgagctgccctgggtg tacttcgtgagcctggtcatctttggatccttcttcgtcctcaaccttgtgctgggcgtc ctcagtggggagttctccaaggagagggaaaaggcaaaagcacgaggggacttccaaaag ctacgggagaagcagcagttggaggaggacctgcggggctacctagactggatcaccaag gctgaggagctggacatggaggacccctctacaggcggcaactctggttctgtggctata atgggccaggctggccaccggcttccacttgccaagctgaccaataggagacttggacgt ctgcgctggttcagtcactccacccgctccacacactccaccagcagccatggtgggggt ctagctaggctggggcagagggcgaatgaacatgcaaccaactctgccccctcccatctc tgctgcagacactgggcatctctgagcaacctggtggcatccctgctcaattcaatgaaa tccatcgcatccctgctgcttctcctcttcctctttatcatcatcttctctctgcttggc atgcagctgttcggcggcaagttcaactttgaccagacccacaccaaacgaagcaccttt gacaccttcccccaggccctcctcactgtctttcagattctgacgggcgaggactggaac gtggtcatgtatgacggtatcatggcctacggcggtcccttcttcccagggatgctagtc tgtatctatttcatcatcctcttcatctgcggcaactacatcttgctgaatgtgtttctt gccattgctgtggacaacctggccagcggagatgcaggcactgccaaggacaagggcagg gaaaagatcactgaggggaacctcccaccggagaatggggcgttggtacctgatgggaag aacgaggaagaagaaggtgcaaggaatgaaggagcaggcaagtgagcagagccaggtgga gaaggcatggaggaggaagaggaagaagaaggtgtggggggtgtggaaatcctgcaggaa gttgtacccaaggagaaggtggtacccatccctgagggcagcgccttcttctgccttagc caaaccaacccgctgaggaaggcctgccacaccctcatccaccatcatatcttcaccaat cttatcctggtgttcatcatcctcagcagcgtctccctggccgctgaggaccccatccga gcccactccttccgcaaccatattctggggtactttgactatgccttcacctccatcttc actgtggagattctactaaagatgaccgtatttggggccttcttgcaccgtggctccttc tgccgtagctggttcaatctgttggatctgctggtggtcagcgtatccctcatctccttt ggcatccattccagtgccatctcagtggtgaagattctgcgagtactccgagtactgagg cccctccgagccatcaacagggccaagggactcaagcatgtggtgcagtgtgtgttcgtg gccattcggaccattgggaatatcatgattgtcaccacactcctgcaattcatgttcgcc tgcattggcgtgcagctcttcaaggggaaattctacagctgcactgatgaggctaaacac actccccaagaatgcaagggctccttcctgatgtaccccgatggagatgtgtcacggccc ctggtccgggaacggctttgggtcaacagcgatttcaactttgacaatgtcctttcagcc atgatggccctgttcactgtctccaccttcgaaggctggcctgcactactatacaaggcc attgatgcacacgcagaagacaagggccccatctataattaccatgtggagatctctgtg ttcttcattgtctacatcatcatcatcgcattcttcatgatgaacatttttgtgggcttt gtcatcatcaccttccgtgcccagggagaacaggagtaccaaaactgtgagctagacaag aaccagcgccagtgcgtggagtatgcactcaaggcccagccactccgccgctacatcccc aagaacccatatcagtatcgcgtgtgggccactgtgaactctgctgccttcgagtacctc atgttcctgctcatcctgctcaacacggttgccctagtcatgcagcactatgagcagact gctcccttcaactatgccatggacatcctcaacatggtcttcactggcctcttcactgtt gagatggtgctcaaaatcatcgccttcaaacccaagcattactttgctgatgcctggaac acatttgatgctcttattgtggtgggcagcgtggtggacattgccgtcactgaagtcaat aatggtggccaccttggtgagagctctgaggacagctcccgcatttccatcaccttcttc cgtcttttccgagtcatgaggctggtcaagcttctcagtaagggtgaaggggtccgcaca ttgctctggacattcatcaagtctttccaggccttgccctatgtggctcttctcattgca atgatattcttcatctatgcagtcattggcatgcagatgtttggcaaggtggctcttcag gatggcacgcagatcaaccgaaacaacaacttccagaccttcccacaggctgtgctgctt ctgttcaggtgtgccactggtgaggcatggcaggagataatgctcgccagccttcctggg aatcggtgtgaccctgagtctgacttcagccccggcgaggagtttacctgtggcagcaat tttgctattgcctattttatcagtttcttcatgctctgtgcctttctgatcataaatctc tttgtggctgtgatcatggacaactttgattatctaaccagagattggtccatcctgggc ccccatcacctggatgaattcaagaggatctggtcggaatacgaccctggggccaagggc cgcatcaagcacctggatgtggttgccctcctgagacgcatccagcccccactgggattc gggaagctgtgcccacaccgtgtagcctgcaagaggcttgtggcgatgaacatgcccctc aactcagatgggacagtgacattcaatgccacactctttgccctggttcggacgtccctg aagatcaagacagaagggaacctggagcaagccaaccaggagctgcggactgtcattaaa aagatttggaagcggatgaagcagaagcttctagatgaggtcatccccccaccagatgag gaggaggtcaccgtgggcaaattctacgccacatttctgatccaggactacttccgcaaa ttccggcggagaaaagaaaaggggctactacggactgaggcccccccaagtacctcctct gttcttcaggctggtctgaggagcctacaagacttgggtcctgagatccggcaggccctc acctgtgacacagatgaggagaaggaggaacaggggcagaagggagaggaggaagaagat gagaaggatccagaaacctaccaagccccaataggctcccagcccccatctcgtcggagt tccatgatttctgtgtctctgcctgttggggacagactccccgactcactctgtcttggg cccagtgatgactatgggaggacttccaactccagacaggccagtatgccccagactgga ttccacacctgcaggagaagctcagagcctctcattttcacaatcccagaagaaggaagt tctaagcccaaaggaaccaaagggcaggacaagcaggacaagaaagaggaagcctctaac ctgctctcctacctagatgagcaggcagagacacccccacgcctggtccttttgccacct cacagaccccagagatatgtggatgggtaccacgccccccatcgccgtctgttgcccccc acccctgcaggtaggaagccctcctttaccatccagtgtctgaggcgccaaggcagctgt gaggatttacccatcccaggcacctatcatcgtgagcgaaattcagggcccagcagggtg cagggttcctgggcaacccctcctcagcaaggtcggctcctatacgccccgctgttgttg gtggaggagggtgcagcaggggaagggtaccttggcaaatccagtggtccacttcgtacc ttcacctgtcttcacatgcctggaacccatttggagcccaaccatggcaagaggagcagt gctgacagcctggtggaggctgtgctcatctctgagggactggacctctttgcccaagac ccacactttgtggccctggccaagcaggagattgcggatgcatgtcgcctgacactggac gagatggacagtaccgctagtgacttgctggcacagggggccagcttgctgtatagcgag gaggagtccatcctctccagcttcgacgaggaggatctgggagacgagatggcctgcatc cacgctctctga

Loxodonta africana (African savanna elephant): 100676022 Help Entry 100676022         CDS       T04351                                  Gene name CACNA2D1 Definition (RefSeq) voltage-dependent calcium channel subunit alpha-2/delta-1   KO K04858   voltage-dependent calcium channel alpha-2/delta-1 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04010   MAPK signaling pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav04921   Oxytocin signaling pathway lav05410   Hypertrophic cardiomyopathy lav05412   Arrhythmogenic right ventricular cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100676022 (CACNA2D1)  09150 Organismal Systems   09152 Endocrine system    04921 Oxytocin signaling pathway     100676022 (CACNA2D1)   09153 Circulatory system    04260 Cardiac muscle contraction     100676022 (CACNA2D1)    04261 Adrenergic signaling in cardiomyocytes     100676022 (CACNA2D1)  09160 Human Diseases   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100676022 (CACNA2D1)    05412 Arrhythmogenic right ventricular cardiomyopathy     100676022 (CACNA2D1)    05414 Dilated cardiomyopathy     100676022 (CACNA2D1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:lav04040]     100676022 (CACNA2D1) Ion channels [BR:lav04040]  Voltage-gated cation channels   Calcium channel, voltage-gated (Cav)    100676022 (CACNA2D1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  VGCC_alpha2 VWA_N VWA VWA_3 VWA_2 dCache_1 IFN-gamma Motif Other DBs NCBI-GeneID:  100676022 NCBI-ProteinID:  XP_023400241 LinkDB All DBs Position Unknown AA seq 1045 aa AA seqDB search MQEDLVTLAKTASGVNQLVDIYEKYQDSYTVEPNNARQLVEIAARDIEKLLSNRSKALVR LAGEAERVQAAHQWREDFASNEVVYYNAKDDLDPERNDSEPGSQRIKPVFIEDANFGRQI SYQHAAVHIPTDIYEGSTIVLNELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYP ASPWVDNSRTPNKIDLYDVRRRPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEM LETLSDDDFVNVASFNSNAQDVSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSF AFEQLLNYNVSRANCNKIIMLFTDGGEERAQEIFAKYNKDKKVRVFTFSVGQHNYDRGPI QWMACENKGYYYEIPSIGAIRINTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLV ITGTLPVFNITGQDENKGNIKNQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNG YVLLHPNLQPKNPKSQEPVTLDFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDER YIDKGNRTYTWTPVNGTDYSLALVLPTYSFYYIKAKIEETITQARYSETLKPDNFEESGY TFIAPRDYCSDLKISDNNTEFLLNFNEFIDRKTPNNPSCNTDLINRILLDAGFTNELVQN YWSKQKNIKGVKARFVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAP YFNKSGPGAYESGIMVSKAVEIYIQGKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPV CDCKRNSDVMDCVILDDGGFLLMANHDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSY DYQSVCEPGAAPKQGAGHRSAYVPSIADILHIGWWATAAAWSILQQVLLSLTFPRLLEAV EMEDDDFTASLSKQSCITEQTQYFFDNDSKSFSGVLDCGNCSRIFHVEKLMNTNLIFIMV ESKGTCPCDTRLLIQAEQTSDGPDPCDMVKQPRYRKGPDVCFDNNNLEDYTDCGGVSGLN PSLWSIIGIQCVLLWLVSGSRHCQL NT seq 3138 nt NT seq  +upstreamnt  +downstreamnt atgcaagaagaccttgtcacactggcaaaaacagcaagtggagtcaatcagcttgttgat atttatgaaaaataccaagattcgtatactgtggaaccaaataatgcacgtcagctggtg gaaattgcagccagagatattgaaaaacttctaagcaacagatctaaggccctggtgcgc ctggctggggaagcagagagagttcaagcagcccaccagtggagggaggattttgcaagc aatgaagttgtctactacaatgcgaaagacgatcttgatcctgaaagaaatgacagcgag ccaggcagccagaggataaaacctgtttttatcgaagatgctaattttggacgacaaata tcttatcagcacgcagcagtccatattcccaccgacatctatgagggctcaacaattgtg ttaaatgaactcaactggacaagtgccttagatgaagttttcaaaaaaaaccgagaggaa gacccttcattgttgtggcaggtgtttggcagtgccacaggcctggccaggtattatcca gcttcaccatgggttgataatagtaggactccaaataagattgacctttatgatgtacgc agaagaccatggtacatccaaggagctgcatctcctaaagacatgcttattcttgttgac gtgagtggaagtgttagtggactgactcttaaactgatccgaacctctgtctctgaaatg ttggaaaccctctcggatgatgatttcgtgaatgtggcctcatttaacagcaatgcccaa gatgtaagctgttttcaacaccttgttcaagcaaatgtaagaaataagaaagtgctgaaa gatgcagtgaataacatcacagcaaaaggaatcacagattataaaaagggctttagtttt gcttttgaacagctgcttaattataatgtttccagagcaaactgcaataaaatcatcatg ttgttcacggatggtggagaagaaagagcccaggagatatttgccaaatacaacaaagat aaaaaagtacgcgtattcacattttcagtcggtcaacataattatgacagaggacctatt cagtggatggcttgtgaaaataaaggttattattatgaaatcccttccattggagctata agaatcaatactcaggaatatttggatgttctgggaagaccaatggttttagcaggagac aaagctaagcaagtccagtggacaaacgtgtatctggatgcattggaactgggtcttgtc attactggaactcttccggtcttcaacataactggccaagatgaaaataagggaaacata aagaaccagctgattcttggtgtgatgggagtagatgtgtctctggaggacattaaaagg ctgacaccacgttttacactgtgccccaatggctattattttgcaattgatcctaatggt tacgttttattacatccaaatcttcagccaaagaaccccaaatctcaggagccagtaaca ctggatttccttgatgcagaattagagaatgatattaaagtggagattcgaaataaaatg atagatggagaaagtggagagaaaacattcagaaccctggttaaatctcaagatgagaga tacattgacaaaggaaatagaacatacacatggactcctgtcaatggcacagattacagt ttggccttggtattaccaacctacagtttttactatataaaagccaaaatagaagagaca ataactcaggccagatattcagaaaccctgaagccagataattttgaagaatctggctac acgttcatagcaccaagagattactgcagtgaccttaaaatatcggataataacactgaa tttcttttaaatttcaacgagttcattgatagaaaaactccaaataatccatcatgtaac acggacttgattaatagaatcttgctggatgcaggctttacaaatgaacttgtccaaaat tactggagtaagcagaaaaacatcaagggagtgaaagcgcgttttgttgtgactgatggt gggattaccagagtgtatcccaaagaagctggagaaaattggcaagaaaacccagagaca tatgaggacagcttttataaaagaagcctggataatgataactatgttttcactgctccc tactttaacaaaagtggacctggtgcctatgaatcaggcattatggtaagcaaagctgta gaaatatatatacaaggaaaacttcttaaacctgcagttgttggaattaaaattgatgta aattcctggatagagaattttaccaaaacttcaatcagggatccgtgtgctggtccagtt tgcgactgcaaaagaaacagtgatgtaatggattgtgtgattctagatgatggtggcttt ctattgatggcaaatcatgatgactatactaaccagattggaagattttttggagagatt gatccgagcttgatgagacaccttgttaatatatcagtttatgcttttaacaaatcttac gattatcagtcggtgtgtgagcccggtgctgcaccaaaacaaggagcagggcatcgctca gcatatgtgccatccatagcagacatattgcacattggctggtgggctactgctgctgcc tggtctattctacagcaggttctcttaagtttgacttttccacgactcctagaggcagtt gagatggaagatgatgacttcacagcttccctgtcaaagcagagctgcattactgaacaa acccagtatttctttgataatgatagtaaatcattcagtggtgtattagactgtggaaat tgttccagaatctttcatgtagaaaagcttatgaacactaacttaatattcataatggtt gagagcaaggggacatgtccctgtgacacacgactgctcatacaagcggagcagacttct gatggtccagatccttgtgatatggttaagcaacccagataccgaaaagggcctgatgtc tgctttgataacaataacctggaggattatactgactgtggtggcgtttctggattaaat ccctccctgtggtctatcatcggaatacagtgtgtactgctttggctggtatctggcagc agacactgccagttatga

Loxodonta africana (African savanna elephant): 104846285 Help Entry 104846285         CDS       T04351                                  Gene name CACNB1 Definition (RefSeq) voltage-dependent L-type calcium channel subunit beta-1 isoform X1   KO K04862   voltage-dependent calcium channel beta-1 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04010   MAPK signaling pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav04921   Oxytocin signaling pathway lav05410   Hypertrophic cardiomyopathy lav05412   Arrhythmogenic right ventricular cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     104846285 (CACNB1)  09150 Organismal Systems   09152 Endocrine system    04921 Oxytocin signaling pathway     104846285 (CACNB1)   09153 Circulatory system    04260 Cardiac muscle contraction     104846285 (CACNB1)    04261 Adrenergic signaling in cardiomyocytes     104846285 (CACNB1)  09160 Human Diseases   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     104846285 (CACNB1)    05412 Arrhythmogenic right ventricular cardiomyopathy     104846285 (CACNB1)    05414 Dilated cardiomyopathy     104846285 (CACNB1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:lav04040]     104846285 (CACNB1) Ion channels [BR:lav04040]  Voltage-gated cation channels   Calcium channel, voltage-gated (Cav)    104846285 (CACNB1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_kin Motif Other DBs NCBI-GeneID:  104846285 NCBI-ProteinID:  XP_023409404 LinkDB All DBs Position Unknown AA seq 553 aa AA seqDB search MFQCLPLHPSRVKGSCSFFALFGLPTGCGGHVGVCWLQSKTVKGIIKLGRLACTVAEVGA KLGSSLSQFFSKTQKRGRACLSLPKSTGLLVLLPAPIQGCLWLPLGMGSRPLFLALSVTN THALLSLLVCPLSLSCPGSFLALCPCLGTLPSPLPFLSWQSLDPAKQKQKSTEHVPPYDV VPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPS KHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIK ITSPKVLQRLIKSRGKSQSRHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYL EAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQPLERATGEHVSV HEYPGELGQPPGLYSSSHPPGRAGTLRALPRQDTFDADTPGSRNSAYTELGDSCVDMETD PSEGPGLGDPAGGSTPPARQGSWEDEEDDYEEELTDNRNRGRNKARYCAEGGGPVLGRNK NELEGWGRGVYIR NT seq 1662 nt NT seq  +upstreamnt  +downstreamnt atgttccagtgtttgcccctgcacccctcccgtgtaaagggaagttgctccttctttgcc ctttttggactcccaacgggctgtggtggacatgtgggggtctgctggctgcagagcaag acagtcaagggaatcattaaattgggcaggttggcatgcactgtagcagaagtgggcgcc aaattagggtcgtcactctcccagttcttttccaagacccagaagaggggtagggcatgt ctaagtcttcccaagtccactggactgttagtcctgctcccagccccaatccagggctgt ctctggctcccccttggcatggggtcccgtcccctctttctggctctgtctgtcactaac acgcatgccctgttatctctcctcgtctgcccgctttccctctcttgtcctggctccttc cttgccctctgcccctgcctgggtaccctcccctctcccctcccctttctctcttggcaa tctctggacccagccaaacagaagcagaagtcgacagagcatgtgcccccctatgacgtg gtaccttccatgagacccatcatcctggtgggaccgtcgctcaagggttatgaggttaca gacatgatgcagaaagctttatttgacttcttgaagcatcgttttgatggcaggatctcc atcactcgtgtgacagcagacatttctctggctaagcgctcagtcctcaacaaccccagc aagcacatcatcattgagcgctctaacacacgttccagtctggctgaggtgcagagtgag attgagcgaatcttcgagctggcccggacccttcagttagtggccctggacgccgacacc atcaaccacccagcccagctctccaagacctcactggcccccatcattgtttacatcaag atcacctctcccaaggtacttcagaggctcatcaagtcccgagggaagtctcagtccaga cacctcaatgtccaaatagcagcctcggagaagctggcacaatgtccccccgaaatgttt gacatcatcctggacgagaatcaattggaggatgcctgcgagcacctggccgaatacttg gaagcctattggaaggccactcacccgcccagcagcactcctcccaatccgctgctgaac cgcacaatggctaccgcagccctggctgccagcccagcccccgtctccaacctccaggga ccctaccttgcttccggggaccagccactggaacgggccaccggggagcacgtcagtgtg cacgagtacccgggggagctgggccagcccccaggcctttactccagcagccacccacca ggccgggcgggcaccctgcgggcactaccccgccaagacacgtttgatgctgacacccct ggcagccgaaactctgcctacacggagctgggagactcgtgtgtggacatggagactgac ccctcggaggggccggggcttggagaccctgcagggggcagcaccccaccagcccggcag ggctcctgggaagatgaggaagacgactatgaggaagagctgactgacaaccggaaccgg ggccggaataaggcccgctactgcgctgagggtgggggtccagttctggggcgcaacaag aatgagctggagggctgggggcgaggtgtctacatccgctga

Loxodonta africana (African savanna elephant): 111749631 Help Entry 111749631         CDS       T04351                                  Gene name CACNG6 Definition (RefSeq) voltage-dependent calcium channel gamma-6 subunit   KO K04871   voltage-dependent calcium channel gamma-6 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04010   MAPK signaling pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav04921   Oxytocin signaling pathway lav05410   Hypertrophic cardiomyopathy lav05412   Arrhythmogenic right ventricular cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     111749631 (CACNG6)  09150 Organismal Systems   09152 Endocrine system    04921 Oxytocin signaling pathway     111749631 (CACNG6)   09153 Circulatory system    04260 Cardiac muscle contraction     111749631 (CACNG6)    04261 Adrenergic signaling in cardiomyocytes     111749631 (CACNG6)  09160 Human Diseases   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     111749631 (CACNG6)    05412 Arrhythmogenic right ventricular cardiomyopathy     111749631 (CACNG6)    05414 Dilated cardiomyopathy     111749631 (CACNG6)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:lav04040]     111749631 (CACNG6) Ion channels [BR:lav04040]  Voltage-gated cation channels   Calcium channel, voltage-gated (Cav)    111749631 (CACNG6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Claudin_2 PMP22_Claudin Phage_holin_3_6 DUF1700 Motif Other DBs NCBI-GeneID:  111749631 NCBI-ProteinID:  XP_023399945 LinkDB All DBs Position Unknown AA seq 167 aa AA seqDB search MRDHHVIASLSFSPAPTEANCTYFKFFTTGQNAHIFQRTTKKEVNLAAAVIAVLGLTIMA LGYLCIIMVLSKGAEFLLRVGAICFGLSGLLLLVSVEVFRHSVQALLERVSSDPPPAPAL AYEYSWSLDCGVAAGLILMLGGGCFLLLTLPSWPWGGLCPKQGRRGT NT seq 504 nt NT seq  +upstreamnt  +downstreamnt atgagggatcaccatgtcatcgcctccctttctttctctcctgctcccacagaagcaaac tgcacctactttaaattctttacaacgggccagaatgcacacatcttccagagaaccaca aagaaagaggttaatctggcagctgcagtgatagcagtgctgggcctgacaatcatggcc ctggggtacctctgtatcatcatggtgctcagcaaaggtgcagagttcctgctccgagtt ggagccatctgttttggcctctcaggcctcctacttctggtgagcgtggaggtgttccgg cattccgtgcaagccctgctcgagagagtcagctctgaccctccgccggccccggccctg gcctacgaatactcctggtctctggactgcggagtggcagccggcctgatcctgatgttg gggggcggctgcttcctgctgctcaccctgccttcctggccctgggggggcctctgtccc aagcaggggcgcaggggcacctag

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