Loxodonta africana (African savanna elephant): 100654178
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Entry
100654178 CDS
T04351
Definition
(RefSeq) cytochrome P450 11B2, mitochondrial-like
KO
K00497
steroid 11beta-monooxygenase [EC:
1.14.15.4
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav00140
Steroid hormone biosynthesis
lav01100
Metabolic pathways
lav04927
Cortisol synthesis and secretion
lav04934
Cushing syndrome
Module
lav_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
100654178
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
100654178
09160 Human Diseases
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100654178
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450 [BR:
lav00199
]
100654178
Enzymes [BR:
lav01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.15.4 steroid 11beta-monooxygenase
100654178
Cytochrome P450 [BR:
lav00199
]
Cytochrome P450, animal type
CYP11 family
100654178
BRITE hierarchy
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Paralog
GFIT
Motif
Pfam:
p450
LSM_int_assoc
Motif
Other DBs
NCBI-GeneID:
100654178
NCBI-ProteinID:
XP_003422469
LinkDB
All DBs
Position
Unknown
AA seq
502 aa
AA seq
DB search
MVLRVQAGMWTTGPRLALHRAQALGTRACPARQAVLPFEAIPQCPGNKWLRMLRIWKEQG
QESLHLEMQKHFEELGPIFRYDVGGVSMVNVMLPKDAEQLQQVDGLHPCRMPLEPWVIYR
HHHGHKLGVFLMNGPEWRHNRLRLNPDLLEPRNIQRFMPLVDTVAQDFIKALRKRVLQNA
RGSLTLDVQSNISLYSIEASNFALYGERLGLLGPNPSPASLDFLQALKAVLKSTTQLSFM
PQSLSRWASANVWAEHFRSWDTIFQYANKAMYNTYQELALGRPQHYSGIVAELLLRSDLP
LDTIKANAVDLTAGSADTTAYTLLMTLFELARNSDVQQALRQESLEAEATIRESSHRVTS
ELPLLRAALKETLRLYPVGLTLQRRVKSDLVLQNYHVPAGTLVFLNLYSLGRNPAVFPRP
ERYDPQRWLTKSSSSNFRHLAFGFGVRQCLGRRLAEAELLLFLHHVLKNFLVKTVSPEDL
KMVYRFVLMPSTYPLLTFQAIN
NT seq
1509 nt
NT seq
+upstream
nt +downstream
nt
atggtgctcagggtgcaggcaggcatgtggaccacggggccccggctggccctgcacagg
gcccaggcactgggcaccagggcctgtccggcccgccaggcagtgctgccctttgaagcc
atcccccagtgtcccggcaacaagtggctgaggatgctgcgtatctggaaggaacagggc
caggagagcctgcacctggagatgcagaaacacttcgaggagctggggcccatcttcagg
tatgacgtgggaggggtgtccatggtgaacgtgatgctgcccaaggacgcagagcagctg
cagcaggtggacggcctgcacccctgcaggatgcccttggagccctgggtgatctaccga
caccatcacgggcacaaactcggcgtgttcttgatgaacgggcccgaatggcgccacaac
cggttgcggctgaacccagacctgctcgaacccagaaatatccagaggttcatgcccctg
gtggacacggtggcccaagacttcatcaaggccctgaggaagagagtgttgcagaatgcc
cgagggagcctgaccctggacgtccagtccaacatctccctctacagcatcgaagccagc
aactttgccctgtatggagagcggctgggcctccttggccccaaccccagcccggccagc
ctggacttcctccaggccttgaaggctgtgttgaaatccaccacgcagctctccttcatg
ccgcagagcctgtcccgttgggccagcgccaacgtgtgggcagagcacttccggtcctgg
gataccatattccagtatgccaacaaagccatgtacaacacctaccaagagctggcgctt
ggccgcccgcagcactacagcggcatcgtggcagagctgctcttacgctcagacctgccc
ctggataccatcaaggccaacgccgtggacctcaccgcagggagcgcagacacgacagcc
tacaccttgctgatgactctcttcgagctggctcgaaactccgatgtgcagcaggccctg
cgccaggagagcctggaggcggaggccaccatcagggaaagctcccacagggtcacctct
gagctgccgctgctgcgagctgccctcaaggagaccctgcggctgtaccccgtgggatta
actctgcagaggcgggtaaagtcggacctggtgctgcagaactatcacgttccggccggg
acattagtcttcttgaacctctactccctgggtcgaaaccccgcggtattcccgaggccc
gagcgctacgacccccagcgctggctgaccaagtcctccagctctaacttccgtcacctg
gccttcggcttcggggtgcgccagtgcctggggcggcggctggcagaggcggagctgctg
cttttcctgcaccacgtgctgaagaacttcctggtgaagactgtatcccccgaggaccta
aagatggtctaccgcttcgtgctgatgccctccacctatcccctcctcaccttccaggcc
atcaactag
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