Loxodonta africana (African savanna elephant): 100654997 Help Entry 100654997         CDS       T04351                                  Gene name FZD2 Definition (RefSeq) frizzled-2   KO K02235   frizzled 2 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04150   mTOR signaling pathway lav04310   Wnt signaling pathway lav04390   Hippo signaling pathway lav04550   Signaling pathways regulating pluripotency of stem cells lav04916   Melanogenesis lav04934   Cushing syndrome lav05010   Alzheimer disease lav05022   Pathways of neurodegeneration - multiple diseases lav05165   Human papillomavirus infection lav05200   Pathways in cancer lav05205   Proteoglycans in cancer lav05217   Basal cell carcinoma lav05224   Breast cancer lav05225   Hepatocellular carcinoma lav05226   Gastric cancer Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     100654997 (FZD2)    04390 Hippo signaling pathway     100654997 (FZD2)    04150 mTOR signaling pathway     100654997 (FZD2)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     100654997 (FZD2)  09150 Organismal Systems   09152 Endocrine system    04916 Melanogenesis     100654997 (FZD2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100654997 (FZD2)    05205 Proteoglycans in cancer     100654997 (FZD2)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     100654997 (FZD2)    05226 Gastric cancer     100654997 (FZD2)    05217 Basal cell carcinoma     100654997 (FZD2)    05224 Breast cancer     100654997 (FZD2)   09164 Neurodegenerative disease    05010 Alzheimer disease     100654997 (FZD2)    05022 Pathways of neurodegeneration - multiple diseases     100654997 (FZD2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100654997 (FZD2)   09172 Infectious disease: viral    05165 Human papillomavirus infection     100654997 (FZD2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:lav04030]     100654997 (FZD2) G protein-coupled receptors [BR:lav04030]  Frizzled / Smoothened family   100654997 (FZD2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Frizzled Fz Motif Other DBs NCBI-GeneID:  100654997 NCBI-ProteinID:  XP_003414548 LinkDB All DBs Position Unknown AA seq 509 aa AA seqDB search MPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPCRSICER ARQGCEALMNKFGFQWPERLRCEHFPRHGAEQICVGQNHSEDGAPALLTTAPPPGLQPGA GGTPGGPGGGGAPPRYATLEHPFHCPRVLKVPSYLSYKFLGERDCAAPCEPARPDGSMFF SQEETRFARLWILTWSVLCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIA GFVLQERVVCNERFSEDGYRTVVQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAA GMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNSLDPLRGFV LAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLERLMVRIGVFSVLYTVPATIV IACYFYEQAFREHWERSWVSQHCKSLAIPCPAHYTPRMSPDFTVYMIKYLMTLIVGITSG FWIWSGKTLHSWRKFYTRLTNSRHGETTV NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgcccaaccttctgggccacacgaaccaggaggacgcgggcctggaggtgcaccagttc tacccgctggtgaaagtgcagtgctcgcccgaactgcgcttcttcctgtgctctatgtac gcgccggtgtgcaccgtgctggagcaggccatcccgccgtgccgctccatttgcgagcgc gcgcgccagggctgcgaggcgctcatgaacaagttcggttttcagtggcccgagcgcctg cgctgcgagcacttcccgcgccacggcgcggagcagatctgcgtgggccaaaaccactca gaggacggcgcccccgcgttgctcactactgcgccgccgccaggcctgcagccgggtgct gggggcacaccaggcggcccgggcggcggcggtgcgccccctcgttacgccacgctggag cacccgttccactgcccccgtgtcctcaaagtgccgtcctatctcagttataaattccta ggcgaacgcgactgcgcggcgccctgcgagccggcgcggccggacggctccatgttcttc tcgcaggaggagacccgctttgcccgcctctggattctcacctggtctgtgctttgctgc gcctccactttcttcactgtcaccacgtacctggtggacatgcagcgcttccgctacccc gagcggccaatcatcttcctgtcgggctgctacacaatggtgtccgtggcctacatcgcg ggcttcgtgctgcaggagcgcgtggtgtgcaacgagcgcttctctgaggacggttaccgc acggtggtgcagggcaccaaaaaggagggctgcaccattctcttcatgatgctctacttc tttagcatggccagctctatctggtgggttatcctgtcactcacctggttcctggcggcc ggcatgaagtggggccacgaagccattgaggccaattcgcagtacttccacttggccgcg tgggccgtgccggctgtcaagaccatcaccatcctggccatgggccagattgacggagac ctgctgagcggcgtgtgcttcgtgggcctaaacagcctggatccgctgcgaggcttcgtg ctggcgccgcttttcgtgtacttgttcattggcacgtccttcctcctggccggcttcgtg tcgctcttccgcatccgaaccatcatgaagcacgacggcaccaagacggagaagctagag cggctcatggtgcgcatcggcgttttctcggtgctctacacggtgcctgccaccatcgtg atcgcctgctatttctacgagcaggccttccgcgagcactgggagcgctcgtgggtaagc cagcactgcaagagcctggccatcccttgcccggcgcactacacgccgcgcatgtcgccc gacttcaccgtctacatgatcaaatacctcatgacgctcatcgtgggcatcacgtcgggc ttctggatctggtctggcaagacgctgcactcgtggaggaagttctacacccgcctcacc aacagccggcacggcgagaccacggtgtaa

Loxodonta africana (African savanna elephant): 100657335 Help Entry 100657335         CDS       T04351                                  Gene name FZD1 Definition (RefSeq) frizzled-1   KO K02432   frizzled 1/7 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04150   mTOR signaling pathway lav04310   Wnt signaling pathway lav04390   Hippo signaling pathway lav04550   Signaling pathways regulating pluripotency of stem cells lav04916   Melanogenesis lav04934   Cushing syndrome lav05010   Alzheimer disease lav05022   Pathways of neurodegeneration - multiple diseases lav05165   Human papillomavirus infection lav05200   Pathways in cancer lav05205   Proteoglycans in cancer lav05217   Basal cell carcinoma lav05224   Breast cancer lav05225   Hepatocellular carcinoma lav05226   Gastric cancer Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     100657335 (FZD1)    04390 Hippo signaling pathway     100657335 (FZD1)    04150 mTOR signaling pathway     100657335 (FZD1)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     100657335 (FZD1)  09150 Organismal Systems   09152 Endocrine system    04916 Melanogenesis     100657335 (FZD1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100657335 (FZD1)    05205 Proteoglycans in cancer     100657335 (FZD1)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     100657335 (FZD1)    05226 Gastric cancer     100657335 (FZD1)    05217 Basal cell carcinoma     100657335 (FZD1)    05224 Breast cancer     100657335 (FZD1)   09164 Neurodegenerative disease    05010 Alzheimer disease     100657335 (FZD1)    05022 Pathways of neurodegeneration - multiple diseases     100657335 (FZD1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100657335 (FZD1)   09172 Infectious disease: viral    05165 Human papillomavirus infection     100657335 (FZD1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:lav04030]     100657335 (FZD1) G protein-coupled receptors [BR:lav04030]  Frizzled / Smoothened family   100657335 (FZD1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Frizzled Fz 7tm_2 Dicty_CAR Motif Other DBs NCBI-GeneID:  100657335 NCBI-ProteinID:  XP_003407202 LinkDB All DBs Position Unknown AA seq 650 aa AA seqDB search MAEEEAPKKSQAAGGGSWELCVGALPARRAAEGSGDRGNGRRPPSDPGRLARRLLLLLWL LEAPLLLGVQAQAAGQGPGQGPGPGQQPPPPPPQQQQSGQQYNGERGISIPDHGYCQPIS IPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVL EQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDKGTPTP SLLPEFWTSNPQYGGGGHRSGGGGFLGGAGASDRGKFSCPRALKVPSYLNYHFLGEKDCG APCEPTKVYGLMYFGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIF LSGCYTAVAVAYIAGFLLEDRVVCNDKFTEDGARTVAQGTKKEGCTILFMMLYFFSMASS IWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVC FVGLNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRI GVFSVLYTVPATIVIACYFYEQAFRDQWERSWVAQSCKSYAIPCPHLQAGGGAPPHPPMS PDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRLTNSKQGETTV NT seq 1953 nt NT seq  +upstreamnt  +downstreamnt atggctgaggaggaggcgcctaagaagtcccaggccgccggcggcgggagctgggaactt tgtgtgggggcgctccctgcccggcgggcggcggaggggagcggggacaggggcaacggt cgccgccccccatctgaccccgggcgcttggcgcgccggctgctgctgctgctttggctg ctagaggctccactgctgctgggggtccaggctcaggcggcgggccaggggccggggcaa gggcccgggccaggccagcagcccccgccgccgccgcctcagcagcagcagagcgggcaa cagtacaacggcgagcgaggcatctccattccggaccacggctactgccagcctatctcc atcccgctgtgcacggacatcgcgtacaaccagaccatcatgcccaacctgctgggccac acgaaccaggaggacgcaggcctcgaggtgcaccagttctatccgctggtgaaggtccag tgctccgctgagcttaagttcttcttgtgctccatgtacgcgcccgtgtgcaccgtgctg gagcaggcgctgccgccctgccgctccctgtgcgagcgcgcgcgccagggttgcgaggcg ctcatgaacaagttcggcttccagtggcccgacacgctcaagtgcgagaagttcccggtg cacggcgccggcgagctgtgcgtgggccagaacacgtccgacaaaggcactccgacgccc tcgctgctgccggagttctggactagcaatccccagtacggcggcgggggccaccgcagc ggcggaggcggcttcctggggggcgccggcgcgtcggaccgaggcaagttctcgtgccct cgtgccctcaaggtaccctcgtacctcaattaccactttctgggggagaaggactgcggg gcgccctgtgagccaaccaaggtgtacgggctcatgtactttgggccggaggagctgcgc ttctcgcgcacctggatcggcatctggtcggtactatgctgcgcctccacactcttcacg gtgcttacgtacctggtggacatgcggcgctttagctaccccgagcgacccatcatcttc ctgtctggctgctacacggctgtggccgtggcctacattgccggcttcctgctggaggac cgggtggtgtgtaacgacaagttcaccgaggatggagcgcgcacggtggcgcagggcacc aagaaggagggctgcaccatcctcttcatgatgctctacttcttcagcatggccagctcc atctggtgggtgatcctgtcactcacctggtttctggcggccggcatgaagtggggccat gaggccatcgaggccaactcgcagtactttcacctggccgcctgggcggtgccggccatc aagaccatcaccatcttggcgctgggccaagtggacggcgacgtgctgagcggggtatgc ttcgtggggcttaacaacgtggacgcactgcgcggttttgtgctggcgcccctcttcgtg tacttattcataggtacgtctttcctgctggctggcttcgtgtcgctcttccgcatccgc accattatgaagcacgacggcaccaaaaccgagaagctggagaagctcatggtgcgcatc ggggtcttcagcgtgctctacacggtgccagccaccatcgtcatcgcctgctacttctat gagcaggccttccgggaccagtgggagcgcagctgggtggcccagagctgcaagagctac gccatcccctgcccccacctccaggcgggtgggggcgccccgcctcacccgcccatgagc ccagacttcacagtcttcatgatcaagtaccttatgacactgatcgtgggcatcacgtca ggcttctggatctggtcgggcaagaccctcaactcctggaggaaattctacaccaggctc accaacagcaaacagggggagaccaccgtctga

Loxodonta africana (African savanna elephant): 100658936 Help Entry 100658936         CDS       T04351                                  Gene name FZD7 Definition (RefSeq) frizzled-7   KO K02432   frizzled 1/7 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04150   mTOR signaling pathway lav04310   Wnt signaling pathway lav04390   Hippo signaling pathway lav04550   Signaling pathways regulating pluripotency of stem cells lav04916   Melanogenesis lav04934   Cushing syndrome lav05010   Alzheimer disease lav05022   Pathways of neurodegeneration - multiple diseases lav05165   Human papillomavirus infection lav05200   Pathways in cancer lav05205   Proteoglycans in cancer lav05217   Basal cell carcinoma lav05224   Breast cancer lav05225   Hepatocellular carcinoma lav05226   Gastric cancer Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     100658936 (FZD7)    04390 Hippo signaling pathway     100658936 (FZD7)    04150 mTOR signaling pathway     100658936 (FZD7)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     100658936 (FZD7)  09150 Organismal Systems   09152 Endocrine system    04916 Melanogenesis     100658936 (FZD7)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100658936 (FZD7)    05205 Proteoglycans in cancer     100658936 (FZD7)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     100658936 (FZD7)    05226 Gastric cancer     100658936 (FZD7)    05217 Basal cell carcinoma     100658936 (FZD7)    05224 Breast cancer     100658936 (FZD7)   09164 Neurodegenerative disease    05010 Alzheimer disease     100658936 (FZD7)    05022 Pathways of neurodegeneration - multiple diseases     100658936 (FZD7)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100658936 (FZD7)   09172 Infectious disease: viral    05165 Human papillomavirus infection     100658936 (FZD7)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:lav04030]     100658936 (FZD7) G protein-coupled receptors [BR:lav04030]  Frizzled / Smoothened family   100658936 (FZD7) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Frizzled Fz Dicty_CAR Motif Other DBs NCBI-GeneID:  100658936 NCBI-ProteinID:  XP_003406180 LinkDB All DBs Position Unknown AA seq 572 aa AA seqDB search MRGPGAAASRSPLGLRALVLALLGALPAGAGAQPYHGEKGISVPDHGFCQPISIPLCTDI AYNQTILPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPC RSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQNTSDGSGGPGPTAYPTA PYLPDLPFTALPPGAADGRGRSTFPFSCPRQLKVPPYLGYRFLGERDCGAPCEPGRANGL MYFKEEERRFARLWVGVWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVALA HVAGFLLEDRAVCVERFSDDGYRTVAQGTKKEGCTILFMVLYFFGMASSIWWVILSLTWF LAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDLLSGVCYVGLSSVDALR GFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPA TIVLACYFYEQAFREHWERTWLLQTCKSYAVPCPPGHFPPMSPDFTVFMIKYLMTMIVGI TTGFWIWSGKTLQSWRRFYHRLSHSSKGETAV NT seq 1719 nt NT seq  +upstreamnt  +downstreamnt atgcggggccccggcgcggccgcgtcgcgctcgcccctgggcctacgcgccctggtgctg gcgctgctgggcgcgctgcccgcgggcgccggggcgcagccgtaccacggcgagaagggc atctcggtgccagaccatggcttctgccagcccatctccatcccgctgtgcacggacatc gcctacaaccagaccatcctgcccaacctgctgggccacacgaaccaagaggacgcgggc ctcgaggtgcaccaattctacccgctagtgaaggtgcagtgctcgcccgagctgcgcttc ttcctgtgctccatgtacgcgcccgtgtgcactgtcctcgagcaggccatcccgccgtgc cgttctctgtgtgagcgcgcccgccagggttgcgaggcgctcatgaacaaattcggcttc cagtggccggagcggctgcgctgcgagaacttcccggtgcacggcgcgggcgagatctgc gtgggccagaacacgtcggacggctccgggggccccggccccacggcctaccccaccgcg ccctacctgcctgacttgcctttcactgcgctgcccccgggggccgcagacggtaggggc cgctccaccttccccttctcgtgccctcgccagctcaaagtgcctccctacctgggctac cgcttcttgggcgagcgcgactgtggcgccccatgcgagcccggccgcgccaacggcctc atgtactttaaggaggaggagaggcgtttcgcccgcctctgggtgggcgtgtggtcggtg ctgtgctgcgcttcgacgctcttcacggtgcttacctacctggtggacatgcggcgcttc agctatcctgagcggcccatcatcttcctgtcgggctgctacttcatggtggccttggca cacgtggccggcttcctgctggaggaccgcgccgtgtgcgtggagcgcttctcggacgac ggctaccgcacggtggcgcagggcaccaagaaggagggctgcaccatccttttcatggtg ctctactttttcggcatggccagctccatctggtgggtcatcctgtcccttacctggttc ctggcggccggcatgaagtggggccacgaggccattgaggccaactcgcagtacttccac ctggccgcatgggccgtgcccgccgtcaagaccatcaccatcctggccatgggccaggtg gatggggacctgctcagcggggtgtgctacgttggcctgtcgagcgtggacgcgctgcgg ggcttcgtgctggcgcccctgtttgtctacctcttcatcggcacgtccttcctgctggcc ggcttcgtgtctctgttccgcatccgcaccatcatgaagcacgacggcaccaagaccgag aagctggagaagctcatggtgcgcatcggcgtctttagcgtgctctacacggtgcctgct accatcgtgctggcctgctacttttacgagcaggcctttcgcgagcactgggagcgcacc tggctcctgcagacctgcaagagctacgccgtgccctgcccgcccggccacttcccgccc atgagccctgacttcaccgtcttcatgatcaagtacctgatgaccatgatcgtgggcatc actacaggcttctggatctggtcgggcaagaccctgcagtcgtggcgccgcttctaccac agactcagccacagcagcaagggggagactgcggtatga

Loxodonta africana (African savanna elephant): 100660631 Help Entry 100660631         CDS       T04351                                  Gene name FZD10 Definition (RefSeq) frizzled-10   KO K02842   frizzled 9/10 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04150   mTOR signaling pathway lav04310   Wnt signaling pathway lav04390   Hippo signaling pathway lav04550   Signaling pathways regulating pluripotency of stem cells lav04916   Melanogenesis lav04934   Cushing syndrome lav05010   Alzheimer disease lav05022   Pathways of neurodegeneration - multiple diseases lav05165   Human papillomavirus infection lav05200   Pathways in cancer lav05205   Proteoglycans in cancer lav05217   Basal cell carcinoma lav05224   Breast cancer lav05225   Hepatocellular carcinoma lav05226   Gastric cancer Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     100660631 (FZD10)    04390 Hippo signaling pathway     100660631 (FZD10)    04150 mTOR signaling pathway     100660631 (FZD10)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     100660631 (FZD10)  09150 Organismal Systems   09152 Endocrine system    04916 Melanogenesis     100660631 (FZD10)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100660631 (FZD10)    05205 Proteoglycans in cancer     100660631 (FZD10)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     100660631 (FZD10)    05226 Gastric cancer     100660631 (FZD10)    05217 Basal cell carcinoma     100660631 (FZD10)    05224 Breast cancer     100660631 (FZD10)   09164 Neurodegenerative disease    05010 Alzheimer disease     100660631 (FZD10)    05022 Pathways of neurodegeneration - multiple diseases     100660631 (FZD10)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100660631 (FZD10)   09172 Infectious disease: viral    05165 Human papillomavirus infection     100660631 (FZD10)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:lav04030]     100660631 (FZD10)    04090 CD molecules [BR:lav04090]     100660631 (FZD10) G protein-coupled receptors [BR:lav04030]  Frizzled / Smoothened family   100660631 (FZD10) CD molecules [BR:lav04090]  Proteins   100660631 (FZD10) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Frizzled Fz Motif Other DBs NCBI-GeneID:  100660631 NCBI-ProteinID:  XP_010599098 LinkDB All DBs Position Unknown AA seq 473 aa AA seqDB search MCEQARLKCSPIMEQFNFKWPDSLDCSKLPNKNDPNYLCMEAPNNGSDEPTRGSGMFPPL FRPQRPHSSQEQQLKDGASARAGCDNPGKFHHVEKSASCAPLCTPGVDVYWSRDDKRFAV VWLAVWSVLCFFSSAFTVLTFLIDPHRFRYPERPIIFLSMCYCVYSVGYIIRLFAGAESI ACDRDSGQLYVIQEGLESTGCTLVFLVLYYFGMASSLWWVILTLTWFLAAGKKWGHEAIE ANSSYFHLAAWAVPAVKTILILVMRRVAGDELTGVCYVGSMDVNALTGFVLIPLACYLII GTSFILSGFVALFHIRRVMKTGGENTDKLEKLMVRIGVFSVLYTVPATCVIACYFYERLN MDYWKVLATQHKCRVNNQTKNVDCLMAASIPAVEIFMVKVFMLLVVGITSGMWIWTSKTL QSWQSVCSRRLKKKSRRKPASVVTSSGIYKKAQHPQKTHHGKYEIPAPPPTCV NT seq 1422 nt NT seq  +upstreamnt  +downstreamnt atgtgcgagcaggcccggctcaaatgctccccgatcatggagcagttcaacttcaagtgg cccgactccctggactgcagcaaactccccaacaagaacgaccccaactacctgtgcatg gaggcgcccaacaacggctcggacgagcccacgcggggctctggtatgttccctccgctc ttccggccgcagcggccgcacagctcgcaggagcagcagctcaaggacggggcgtccgcg cgcgctggctgcgacaaccccggcaagttccaccatgtggagaagagcgcgtcgtgcgcg ccgctctgcacgcccggcgtggacgtgtactggagtcgcgacgacaagcgcttcgccgtg gtctggctggctgtctggtccgtgctctgctttttctccagcgccttcacggtgctcacc ttcctcatcgaccctcatcgcttcaggtaccccgagcgccccatcatcttcctgtccatg tgctactgcgtctactcggtgggctacatcatccgcctctttgcgggcgcagagagcatc gcctgcgaccgggacagcgggcagctctatgtcatccaggagggcctggagagcaccggc tgcacgctggtgttcctggttctctactactttggcatggccagctcgctctggtgggtc atcctcacgctcacctggttcttggcggccggcaagaagtggggccacgaggccatcgag gccaacagcagctacttccatctggcggcctgggccgtccccgcggtgaagaccatcctg atcctggtgatgcgcagggtggcgggggacgagctcaccggcgtgtgctacgtgggcagc atggacgtcaacgccctcaccggcttcgtgctcatccccctggcctgctacctcatcatc ggcacctccttcattctctcgggcttcgtggccctcttccacatccggagggtgatgaag acgggcggggagaacacggacaagctggagaaactcatggtgcgcatcggagtcttctcc gtgctctacacggtgccggccacctgtgtgatcgcctgctacttctacgaacgcctcaac atggattactggaaagtcctagccacgcagcacaagtgcagagtgaacaaccagaccaag aacgtggactgcctgatggccgcctccatccccgccgtggagatcttcatggtgaaggtg ttcatgctgctggttgtgggtatcaccagcggtatgtggatctggacctcaaagactctg cagtcctggcagagcgtctgcagccgtaggctgaagaagaagagcaggcggaaacccgcc agcgtggtcaccagcagtgggatttacaaaaaagcccagcacccgcaaaaaacccatcac gggaaatacgaaatccccgccccgcctcccacctgtgtgtga

Loxodonta africana (African savanna elephant): 100666465 Help Entry 100666465         CDS       T04351                                  Gene name FZD3 Definition (RefSeq) frizzled-3   KO K02329   frizzled 3 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04150   mTOR signaling pathway lav04310   Wnt signaling pathway lav04360   Axon guidance lav04390   Hippo signaling pathway lav04550   Signaling pathways regulating pluripotency of stem cells lav04916   Melanogenesis lav04934   Cushing syndrome lav05010   Alzheimer disease lav05022   Pathways of neurodegeneration - multiple diseases lav05165   Human papillomavirus infection lav05200   Pathways in cancer lav05205   Proteoglycans in cancer lav05206   MicroRNAs in cancer lav05217   Basal cell carcinoma lav05224   Breast cancer lav05225   Hepatocellular carcinoma lav05226   Gastric cancer Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     100666465 (FZD3)    04390 Hippo signaling pathway     100666465 (FZD3)    04150 mTOR signaling pathway     100666465 (FZD3)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     100666465 (FZD3)  09150 Organismal Systems   09152 Endocrine system    04916 Melanogenesis     100666465 (FZD3)   09158 Development and regeneration    04360 Axon guidance     100666465 (FZD3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100666465 (FZD3)    05206 MicroRNAs in cancer     100666465 (FZD3)    05205 Proteoglycans in cancer     100666465 (FZD3)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     100666465 (FZD3)    05226 Gastric cancer     100666465 (FZD3)    05217 Basal cell carcinoma     100666465 (FZD3)    05224 Breast cancer     100666465 (FZD3)   09164 Neurodegenerative disease    05010 Alzheimer disease     100666465 (FZD3)    05022 Pathways of neurodegeneration - multiple diseases     100666465 (FZD3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100666465 (FZD3)   09172 Infectious disease: viral    05165 Human papillomavirus infection     100666465 (FZD3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:lav04030]     100666465 (FZD3) G protein-coupled receptors [BR:lav04030]  Frizzled / Smoothened family   100666465 (FZD3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Frizzled Fz Motif Other DBs NCBI-GeneID:  100666465 NCBI-ProteinID:  XP_003412505 UniProt:  G3T897 LinkDB All DBs Position Unknown AA seq 666 aa AA seqDB search MAMSWIVFYLWALAMFVGCISGHSSFSCEPITLRMCQDLPYNTTFMPNLLNHYDQQTAAL AMEPFHPMVNLDCSRDFRPFLCALYAPICMEYGRVTLPCRRLCQRAYSECSKLMEMFGVP WPEDMECSRFPDCDEPYPRLVDLNLAGDPTEGAPVAVQRDYGFWCPRELKIDPDLGYSFL HVRDCSPPCPNMYFRREELSFARYFIGLISIICLSATLFTFLTFLIDVTRFRYPERPIIF YAVCYMMVSLIFFIGFLLEDRVACNASSPAQYKASTVTQGSHNKACTMLFMVLYFFTMAG SVWWVILTITWFLAAVPKWGSEAIEKKALLFHASAWGIPGTLTIILLAMNKIEGDNISGV CFVGLYDVDALRYFVLAPLCLYVVVGVSLLLAGIISLNRVRIEIPLEKENQDKLVKFMIR IGVFSILYLVPLLVVIGCYFYEQAYRGIWETTWIQERCREYHIPCPYQVTQMSRPDLILF LMKYLMALIVGIPSIFWVGSKKTCFEWASFFHGRRKKEIVNESRQVLQEPDFAQSLLRDP NTPIIRKSRGTSTQGTSTHASSTQLAMVDDQRSKAGSVHSKVSSYHGSLHRSRDGRYTPC SYRGMEERLPHGSMSRLTDHSRHSSSHRLNEQSRHSSIRDLSSNPMTHITHGTSMNRVIE EDGTSA NT seq 2001 nt NT seq  +upstreamnt  +downstreamnt atggctatgagttggattgtcttctatctttgggccttggctatgtttgtgggatgcata agtgggcatagttcgttttcttgtgaacctattaccttgagaatgtgccaagatttgcct tataatactaccttcatgcctaatcttttgaatcattatgaccaacaaacagcagcttta gcaatggagccattccaccctatggtgaacctggattgctctcgggatttccggccattt ctttgtgcactctacgctcctatttgtatggaatacggacgtgtcacacttccttgtcgt aggctatgtcagcgggcctacagtgagtgttcgaagctcatggaaatgtttggtgttcct tggcctgaagatatggaatgtagtaggtttccagattgtgatgagccatatcctcgactt gtggatctgaatttagctggagaccctacggaaggagccccagtggcagtgcagagggac tatggcttttggtgtccccgagagttgaaaattgatcctgaccttggttattcttttttg cacgtgcgtgattgttcacctccttgtccaaatatgtactttaggagagaagaactttca tttgctcgatatttcataggactgatttcaatcatttgcctctctgccacattgtttact tttttaacttttttgattgatgttacaagattccgctatcctgaaagacctattatattt tatgcagtctgctacatgatggtatcattaattttcttcattgggtttttactcgaggat cgagtagcctgcaatgcatctagccctgcccagtataaggcttccacagtgacacaagga tctcacaataaagcctgtaccatgctttttatggtactctatttctttactatggctggc agcgtttggtgggtaattcttaccatcacatggttcttggcagctgtgccaaagtggggc agtgaagctattgagaagaaagcattgctgtttcacgccagtgcatggggcatccctgga actctaactatcatcctgttagcgatgaataaaattgaaggtgacaatattagtggcgtg tgttttgttggcctctacgatgttgatgcattgagatattttgttcttgctcccctctgc ctatatgtggtagttggggtttctctcctcttagctggcattatatccctaaacagagtt cgaattgagattccgttagaaaaggaaaaccaagataaattggtgaagtttatgatccgg attggtgttttcagcattctttatcttgtaccactcttggttgtaattggatgctacttt tatgagcaagcttaccgtggcatttgggaaacaacatggatacaagaacgctgcagagaa tatcacattccatgtccatatcaggttactcaaatgagtcgtcctgacctgatccttttt ctgatgaaatacctgatggcactcatagtcggtattccctccattttttgggttggaagc aagaaaacatgttttgaatgggccagttttttccatggtcgtaggaaaaaagagatagtg aatgagagccgacaggtactccaggaacctgattttgctcagtccctcctaagagatccg aatactcctattataagaaaatcaagaggaacatccactcaaggaacatccacacatgct tcttcaactcaactggctatggtggatgatcagagaagcaaagcaggtagtgtccacagc aaagtgagcagctaccatggcagcctccacagatcacgtgatggcaggtacactccctgc agttacaggggaatggaggaaagactacctcatggcagcatgtcacgactaacagatcac tccaggcacagtagttctcatcggctcaatgaacagtcacgacatagcagcatcagagat ctcagtagtaatcccatgactcacatcacacatggcacaagtatgaatcgggttattgaa gaagacggaaccagcgcttaa

Loxodonta africana (African savanna elephant): 100666499 Help Entry 100666499         CDS       T04351                                  Gene name FZD8 Definition (RefSeq) LOW QUALITY PROTEIN: frizzled-8   KO K02375   frizzled 5/8 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04150   mTOR signaling pathway lav04310   Wnt signaling pathway lav04390   Hippo signaling pathway lav04550   Signaling pathways regulating pluripotency of stem cells lav04916   Melanogenesis lav04934   Cushing syndrome lav05010   Alzheimer disease lav05022   Pathways of neurodegeneration - multiple diseases lav05165   Human papillomavirus infection lav05200   Pathways in cancer lav05205   Proteoglycans in cancer lav05217   Basal cell carcinoma lav05224   Breast cancer lav05225   Hepatocellular carcinoma lav05226   Gastric cancer Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     100666499 (FZD8)    04390 Hippo signaling pathway     100666499 (FZD8)    04150 mTOR signaling pathway     100666499 (FZD8)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     100666499 (FZD8)  09150 Organismal Systems   09152 Endocrine system    04916 Melanogenesis     100666499 (FZD8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100666499 (FZD8)    05205 Proteoglycans in cancer     100666499 (FZD8)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     100666499 (FZD8)    05226 Gastric cancer     100666499 (FZD8)    05217 Basal cell carcinoma     100666499 (FZD8)    05224 Breast cancer     100666499 (FZD8)   09164 Neurodegenerative disease    05010 Alzheimer disease     100666499 (FZD8)    05022 Pathways of neurodegeneration - multiple diseases     100666499 (FZD8)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100666499 (FZD8)   09172 Infectious disease: viral    05165 Human papillomavirus infection     100666499 (FZD8)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:lav04030]     100666499 (FZD8) G protein-coupled receptors [BR:lav04030]  Frizzled / Smoothened family   100666499 (FZD8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Frizzled Fz 7tm_2 PhaG_MnhG_YufB Motif Other DBs NCBI-GeneID:  100666499 NCBI-ProteinID:  XP_023395552 LinkDB All DBs Position Unknown AA seq 553 aa AA seqDB search MEWSYLLEVTSLLAAFALLQRSSGAAAASAKELACQEITVPLCKGIGYNYTYMPNQFNHD TQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAP LMRQYGFAWPDRMRWDRLPEXGNPDTLCMDWRRISNPVAAHHLFLACYLFVSVGYLVRLV AGHEKVACSGGAPGPGGAGPAGGAAAAAAGAGAAGAGAGGPGGRGEYEELGAVEQHVRYE TTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLVP SVKSIAVLALSSVDGDPVAGICYVGNQSLDNLRGFVLAPLVIYLFIGTMFLLAGFVSLFR IRSVIKQQGGPTKTHKLEKLMIRLGLFTVLYTVPAAVVVACLFYEQHNRPRWEATHNCPC LRDLQPDQARRPDYAVFMLKYFMCLVVGITSGVWVWSGKTLESWRALCTRCCWASKGXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPGGGGGPGGGGGSLYSDVSTGLTWRSGTAS SVSYPKQMPLSQV NT seq 1662 nt NT seq  +upstreamnt  +downstreamnt atggagtggagttacctgttggaagtgacctcgctgctggccgccttcgcgctgttgcag cgctcgagcggcgcggcggccgcctcggccaaagagctggcgtgccaggagatcacggtg cccctgtgcaagggcatcggctacaactacacctacatgcccaaccagttcaaccacgac acgcaggacgaggcgggcctggaggtgcaccagttctggccactggtagagatccagtgc tcgcccgacctcaagttcttcctgtgcagcatgtacacgcccatctgcctggaagactac aaaaagccgctgccgccctgccgctcggtgtgcgagcgcgccaaggccggctgcgcgccg ctcatgcgccagtacggcttcgcctggcccgaccgcatgcgctgggaccggctgccggag ncaggcaaccccgacacgttatgcatggactggagacgtataagtaacccggtagcggcc catcatttgttcttagcctgctacctcttcgtgtcggtaggctacctggtgcgcctagtg gcaggccacgagaaggtggcgtgcagcggcggcgcgcccggcccgggcggcgcgggacct gcgggcggtgcggcggcggcggcggcgggcgcgggcgcagcgggagcgggcgcgggcggc ccgggcgggcgcggcgagtacgaggaactgggcgccgtggagcagcacgtgcgctacgag accacgggcccggccctgtgtactgtcgtcttcctgctggtctacttcttcggcatggcc agctccatctggtgggtgatcctgtcgctcacgtggttcctggcggccggcatgaagtgg ggcaacgaggccatcgccggctactcgcagtacttccacctggccgcgtggctcgtgccc agcgtcaagtccatcgccgtgctggcgctcagctcggtggacggggacccggtggcgggc atctgctacgtgggcaaccagagcctcgacaacctgcgcggcttcgtgctggcaccgctg gtcatctacctcttcatcggcaccatgtttctgctggcgggcttcgtgtcgctcttccgc atccgctcggtcatcaagcagcagggcgggcccaccaagacgcacaagctggagaagctc atgatccgcctgggcctcttcaccgtgctctacaccgtgcccgccgccgtcgtggtcgcc tgcctcttctacgagcagcacaaccgcccgcgctgggaggccacgcacaactgcccgtgc ctgcgggacctgcagcccgaccaggcccgtcggcctgactacgccgtgttcatgctgaag tacttcatgtgcctcgtggtgggcatcacctcgggcgtgtgggtctggtctggcaagacg ctcgagtcctggcgcgccctgtgcacccgctgctgctgggccagcaagggcnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnncccggcgggggcgggggaccgggcggcggc gggggctccctctacagcgacgtcagcaccggcctgacgtggaggtctggcacggccagc tccgtgtcttaccccaagcagatgccattgtcccaggtctga

Loxodonta africana (African savanna elephant): 100674586 Help Entry 100674586         CDS       T04351                                  Gene name FZD5 Definition (RefSeq) frizzled-5   KO K02375   frizzled 5/8 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04150   mTOR signaling pathway lav04310   Wnt signaling pathway lav04390   Hippo signaling pathway lav04550   Signaling pathways regulating pluripotency of stem cells lav04916   Melanogenesis lav04934   Cushing syndrome lav05010   Alzheimer disease lav05022   Pathways of neurodegeneration - multiple diseases lav05165   Human papillomavirus infection lav05200   Pathways in cancer lav05205   Proteoglycans in cancer lav05217   Basal cell carcinoma lav05224   Breast cancer lav05225   Hepatocellular carcinoma lav05226   Gastric cancer Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     100674586 (FZD5)    04390 Hippo signaling pathway     100674586 (FZD5)    04150 mTOR signaling pathway     100674586 (FZD5)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     100674586 (FZD5)  09150 Organismal Systems   09152 Endocrine system    04916 Melanogenesis     100674586 (FZD5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100674586 (FZD5)    05205 Proteoglycans in cancer     100674586 (FZD5)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     100674586 (FZD5)    05226 Gastric cancer     100674586 (FZD5)    05217 Basal cell carcinoma     100674586 (FZD5)    05224 Breast cancer     100674586 (FZD5)   09164 Neurodegenerative disease    05010 Alzheimer disease     100674586 (FZD5)    05022 Pathways of neurodegeneration - multiple diseases     100674586 (FZD5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100674586 (FZD5)   09172 Infectious disease: viral    05165 Human papillomavirus infection     100674586 (FZD5)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:lav04030]     100674586 (FZD5) G protein-coupled receptors [BR:lav04030]  Frizzled / Smoothened family   100674586 (FZD5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Frizzled Fz Motif Other DBs NCBI-GeneID:  100674586 NCBI-ProteinID:  XP_023397773 LinkDB All DBs Position Unknown AA seq 585 aa AA seqDB search MARLDPSAPPPLLLLLLAQLVGRAAAASKAPVCQEITVPMCRGIGYNLTHMPNQFNHDTQ DEAGLEVHQFWPLVEIHCSPDLRFFLCSMYTPICLEDYHKPLPPCRSVCERAKAGCSPLM RQYGFAWPERMSCDRLPVLGRDAEVLCMDYNRSEATTAPPRPFTAKPTHPGLPGAPASGV ECAAGGPSVCKCREPFVPILKESHPLYNKVRTGQVPNCAVPCYQPSFSPDERTFATFWIG LWSVLCFISTSTTVATFLIDMERFRYPERPIIFLSACYLCVSLGFLVRLVVGHASVACSR EHSHIHYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYF HLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQNLNSLRGFVLGPLVLYLLVGTLFLL AGFVSLFRIRSVIKQGGTKTDKLEKLMIRIGIFTLLYTVPASIVVACYLYEQHYRESWEA ALTCACPGPDAGQPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTVESWRRFTSRCCCR RRRGHKSGGARAAADYAEASAALTSRTGPLGPAAAYHKQVSLSHV NT seq 1758 nt NT seq  +upstreamnt  +downstreamnt atggctcggcttgacccgtccgcaccgcccccgctgctgctgctgctcctggcgcagctg gtgggccgggcggcggccgcctccaaggccccggtgtgccaggagatcacggtccccatg tgccgcggcatcggctacaacttgacgcacatgcccaaccagttcaatcacgacacgcag gacgaggccggcctggaggtgcaccagttctggccgctggtggagatccactgctcgccg gacctgcgcttcttcctgtgctccatgtacacgcccatctgcttggaagactaccacaag cctctgccgccctgccgctccgtgtgcgagcgcgccaaggccggctgctcgccgctcatg cgccagtacggcttcgcctggccggagcgcatgagctgcgaccgcctcccagtcctgggc cgcgatgccgaggtcctgtgcatggattacaaccgcagtgaggctaccacggcgcccccc cggcccttcacggccaagcccacacacccaggcctgccaggggcgccagcctccggggtc gagtgtgccgccgggggcccgtcggtgtgcaagtgccgcgaaccattcgtgcccatcctg aaggagtcgcaccccctgtacaacaaggtgcggacgggccaggtgcccaactgcgcggtg ccttgctatcagccgtccttcagccccgacgagcgcacgttcgccaccttctggattggc ctgtggtcggtgctgtgcttcatctccacctccaccacggtggccaccttcctcatcgac atggagcgcttccgataccccgagcgccccatcatcttcctgtccgcctgctacttatgc gtgtcgctgggtttcctggtgcgcctggttgtgggccatgccagtgttgcatgcagccgc gagcacagccacatccactacgagactaccggcccagcattgtgcaccgtcgtcttcctg cttgtctacttcttcggcatggccagctccatctggtgggtcatcctgtcactcacctgg ttcctggcggctggcatgaagtggggcaacgaggcgatcgcgggctatgcacagtacttc cacctggctgcttggctcatccctagcgtcaagtccattacggcgttggcgctgagctct gtagacggtgacccggtggctggcatctgctacgtaggcaaccagaacctgaactcgttg cgtggcttcgttctgggcccgctggtgctctacctgctcgtgggcacgctcttccttctg gcgggctttgtgtcgctcttccgcatccgtagtgtcatcaagcagggcggcaccaagacg gacaaactggagaagctcatgatccgcataggcattttcacgctactgtacacagtgccc gccagcatcgtggtggcctgctacctgtatgagcagcactaccgcgagagctgggaggcg gccctcacctgcgcgtgcccgggccccgacgccggccagccgcgcgccaagccggagtac tgggtgctcatgctcaagtacttcatgtgcctcgtggtgggcatcacgtcgggcgtctgg atctggtccggcaagacggtggagtcgtggcggcgcttcaccagccgctgctgctgccgt cggcggcggggccacaagagcggcggcgccagggccgcggcggactacgccgaggcgagc gcggcactgacgagcaggaccgggccgctgggccccgccgccgcctaccacaagcaggtg tccctgtcgcacgtgtag

Loxodonta africana (African savanna elephant): 100675317 Help Entry 100675317         CDS       T04351                                  Gene name FZD4 Definition (RefSeq) frizzled-4   KO K02354   frizzled 4 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04150   mTOR signaling pathway lav04310   Wnt signaling pathway lav04390   Hippo signaling pathway lav04550   Signaling pathways regulating pluripotency of stem cells lav04916   Melanogenesis lav04934   Cushing syndrome lav05010   Alzheimer disease lav05022   Pathways of neurodegeneration - multiple diseases lav05165   Human papillomavirus infection lav05200   Pathways in cancer lav05205   Proteoglycans in cancer lav05217   Basal cell carcinoma lav05224   Breast cancer lav05225   Hepatocellular carcinoma lav05226   Gastric cancer Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     100675317 (FZD4)    04390 Hippo signaling pathway     100675317 (FZD4)    04150 mTOR signaling pathway     100675317 (FZD4)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     100675317 (FZD4)  09150 Organismal Systems   09152 Endocrine system    04916 Melanogenesis     100675317 (FZD4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100675317 (FZD4)    05205 Proteoglycans in cancer     100675317 (FZD4)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     100675317 (FZD4)    05226 Gastric cancer     100675317 (FZD4)    05217 Basal cell carcinoma     100675317 (FZD4)    05224 Breast cancer     100675317 (FZD4)   09164 Neurodegenerative disease    05010 Alzheimer disease     100675317 (FZD4)    05022 Pathways of neurodegeneration - multiple diseases     100675317 (FZD4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100675317 (FZD4)   09172 Infectious disease: viral    05165 Human papillomavirus infection     100675317 (FZD4)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:lav04030]     100675317 (FZD4)    04090 CD molecules [BR:lav04090]     100675317 (FZD4) G protein-coupled receptors [BR:lav04030]  Frizzled / Smoothened family   100675317 (FZD4) CD molecules [BR:lav04090]  Proteins   100675317 (FZD4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Frizzled Fz Chol_subst-bind Motif Other DBs NCBI-GeneID:  100675317 NCBI-ProteinID:  XP_003418598 UniProt:  G3UE67 LinkDB All DBs Position Unknown AA seq 536 aa AA seqDB search MGRRGAGPRVPGEPGGVGLSLRLLLLLLLLGPARGFGDEEERRCDPIRITMCQNLGYNVT KMPNLVGHELQTDAELQLTTFTPLIQYGCSSQLQFFLCSVYVPMCTEKINIPIGPCGGMC LSVKRRCEPVLKEFGFAWPESLNCSKFPPQNDHNHMCMEGPGDEEVPLPHKTPIQPGEEC HSVGTNSDQYIWVKRSLNCVLKCGYDAGLYSRSAKEFTDIWMAVWASLCFISTAFTVLTF LIDSSRFSYPERPIIFLSMCYNIYSIAYIVRLTVGRERISCDFEEAAEPVLIQEGLKNTG CAIIFLLMYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAVKTIV ILIMRLVDADGLTGLCYVGNQNLDALTGFVVAPLFTYLVIGTLFIAAGLVALFKIRSNLQ KDGTKTDKLERLMVKIGVFSVLYTVPATCVIACYFYEISNWALFRYSADDSNMAVEMLKI FMSLLVGITSGMWIWSAKTFHTWQKCSNRLVNSGKVKREKRGSGWVKPGKGNETVV NT seq 1611 nt NT seq  +upstreamnt  +downstreamnt atgggccggcggggcgcggggccgagagtcccgggggagcccgggggcgtcgggctgagt ctgcggctgctgctgctgctgctgctcttggggccggcgcggggctttggggacgaggag gagcggcgctgcgaccccattcgcatcaccatgtgccagaacctcggctacaacgtgacc aaaatgcccaacctggtggggcacgagctgcagacggacgccgagctgcagctgacaacc ttcacgccgctcatccagtacggctgctccagccagctgcagttcttcctttgttcggtt tatgtgccaatgtgcacagagaagatcaacatccccatcggcccatgcggcggcatgtgt ctttcagtcaagagacgctgtgaaccggtcctgaaggaatttggattcgcctggccagag agcctgaactgcagcaaattcccaccacagaatgaccacaatcacatgtgcatggaaggg ccaggtgacgaagaggtacctttacctcacaaaacccccatccagcctggggaagaatgt cactctgtgggaaccaattctgaccagtacatctgggtgaaaaggagcctgaactgtgtt ctcaagtgtggctatgatgccggtttatacagccgctcggccaaggagttcaccgacatc tggatggccgtgtgggccagcctgtgcttcatctccaccgccttcacggtcctgaccttc ctgatcgattcctccaggttttcctaccctgagcgccccatcatatttctcagtatgtgc tataatatttatagcattgcttatattgtcaggctgactgtaggccgggaaaggatatcc tgcgattttgaagaggcagcagaacccgttctcatccaagaaggacttaagaacacagga tgtgcaataattttcttgctgatgtacttttttggaatggctagctctatctggtgggtt attctgacactcacttggtttttggcagccggactcaaatggggtcatgaagccattgaa atgcacagttcttatttccacattgcagcctgggccatccctgcggtgaaaaccattgtc atcttgatcatgagactggtggatgcagatggactgactggcctgtgctatgttggaaac caaaaccttgatgccctcactggctttgtggtggctcccctcttcacttatttggtgatc ggaactttattcattgctgcaggtttggtggccttgttcaaaattcggtcaaatcttcaa aaggatgggacaaagacagacaagttggaaaggctgatggtcaaaattggagtcttctca gtactgtacacggttcctgcaacctgtgtgattgcctgttatttctatgaaatttccaac tgggcactcttccggtattctgcagatgactccaatatggcagttgaaatgttaaaaatt tttatgtctttgctggtgggcatcacttcaggcatgtggatttggtctgccaaaactttt cacacgtggcagaaatgttccaacagattggtgaactctgggaaggtaaagagagagaag agagggagtggttgggtaaagcctgggaaaggcaatgaaactgtggtataa

Loxodonta africana (African savanna elephant): 100677440 Help Entry 100677440         CDS       T04351                                  Gene name FZD6 Definition (RefSeq) frizzled-6   KO K02376   frizzled 6 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04150   mTOR signaling pathway lav04310   Wnt signaling pathway lav04390   Hippo signaling pathway lav04550   Signaling pathways regulating pluripotency of stem cells lav04916   Melanogenesis lav04934   Cushing syndrome lav05010   Alzheimer disease lav05022   Pathways of neurodegeneration - multiple diseases lav05165   Human papillomavirus infection lav05200   Pathways in cancer lav05205   Proteoglycans in cancer lav05217   Basal cell carcinoma lav05224   Breast cancer lav05225   Hepatocellular carcinoma lav05226   Gastric cancer Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     100677440 (FZD6)    04390 Hippo signaling pathway     100677440 (FZD6)    04150 mTOR signaling pathway     100677440 (FZD6)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     100677440 (FZD6)  09150 Organismal Systems   09152 Endocrine system    04916 Melanogenesis     100677440 (FZD6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100677440 (FZD6)    05205 Proteoglycans in cancer     100677440 (FZD6)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     100677440 (FZD6)    05226 Gastric cancer     100677440 (FZD6)    05217 Basal cell carcinoma     100677440 (FZD6)    05224 Breast cancer     100677440 (FZD6)   09164 Neurodegenerative disease    05010 Alzheimer disease     100677440 (FZD6)    05022 Pathways of neurodegeneration - multiple diseases     100677440 (FZD6)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100677440 (FZD6)   09172 Infectious disease: viral    05165 Human papillomavirus infection     100677440 (FZD6)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:lav04030]     100677440 (FZD6) G protein-coupled receptors [BR:lav04030]  Frizzled / Smoothened family   100677440 (FZD6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Frizzled Fz Folate_rec Integrin_alpha RseC_MucC Motif Other DBs NCBI-GeneID:  100677440 NCBI-ProteinID:  XP_003408475 UniProt:  G3SS79 LinkDB All DBs Position Unknown AA seq 712 aa AA seqDB search MEMFTFLLCIFLPLIRGHSLFTCEPITVPRCVKMAYNMTFFPNLMGHYDQGTAAKVMEHF LPLANLECSPNVETFLCKAFVPSCTEQIHVVPPCRKFCEKVYSDCKKIIDTFDIQWPEEL ECDRLQYCDETVPTTSDPPTKFLDPQKKTEEVQRDIGFWCPRHLKTSGGQGYKFLGLDQC APPCPNMYFKSDELEFAKSFIGIVSIFCLCATLFTFLTFLIDVKRFRYPERPIIYYSVCY SIVSLMYFIGFLLGNSTACNKADEKLELGDTVILGSQNKACTVLFMFLYFFTMAGTVWWV ILTITWFLAAGRKWSCEAIEQKAVWFHAVAWGVPGFLTVMLLAMNKVEGDNISGVCFVGL YDLDASRYFVLLPLCLCVFVGLSLLLAGIISLNHVRQVIQHDGRNQEKLKKFMIRIGVFS GLYLVPLVTLLGCYVYEQVNRITWEITWVSDHCRQYHIPCPYQAKTTARPELALFMIKYL MTLIVGISAVFWVGSKKTCTEWAGFFKRNRKRDPISESRRVLQESCEFFLKHNSKVKHKK KHYKPSSHKLKVISKSMGTSTGATANHGASAVAITNHDYLGQETLTEIQTSPETSVRDMG ADGASTPKLREQDCGDPSSPAASSSKLSGEQANRKGRKAANVNDKSSVSESVRSEGRVNP KNDFTETVPVQSNNLQMPSSSQPSSLKGSTSLLVHSVSGVRKEQDAGSHSDA NT seq 2139 nt NT seq  +upstreamnt  +downstreamnt atggagatgtttacatttttgctatgtatttttctacccctcataagagggcatagtctc ttcacctgtgaaccgattactgttcccaggtgtgtgaaaatggcctacaatatgacattt ttccctaatctgatgggtcattatgaccagggtactgctgctaaggtaatggagcatttt cttcctctcgcaaatctggaatgttcaccaaatgttgaaactttcctttgtaaagcgttt gtaccaagctgcacagaacaaattcatgtggttccaccttgccgtaaattttgtgagaaa gtatattctgattgcaaaaaaataattgacacttttgacatccaatggcctgaggaactt gaatgtgacagattacaatactgtgatgagacagttcctacaacttctgatccacccaca aaatttcttgaccctcagaagaaaacagaagaagtccaaagagacattggattttggtgt ccaagacatctcaagacctctggaggacaaggctataagtttctgggccttgaccagtgt gcgcctccttgtcccaacatgtattttaaaagtgatgagctagagtttgcaaaaagtttt atcggaatagtttccatattctgtctttgtgcaactttgttcacatttctgactttttta attgatgttaaaagatttagatacccagagagaccaattatatattactccgtctgttac agcattgtatcgcttatgtactttattggctttttgctcggcaatagtacagcctgtaat aaggcagatgaaaagctagagcttggtgacacagttattctaggctctcagaataaggct tgcactgttttatttatgtttttgtattttttcacaatggctggcactgtgtggtgggtg attcttaccattacttggttcttagctgcaggaagaaaatggagttgtgaagccattgaa caaaaagcagtgtggttccatgccgtcgcgtggggagtaccaggttttctaactgttatg cttcttgctatgaacaaagttgaaggagataatatcagtggagtttgctttgttggcctt tatgacctggatgcttctcgttactttgtactcttgccactgtgcctttgtgtgtttgtt ggcctttctcttcttttagctggaattatttctttaaatcatgttcgacaagttatacaa catgatggtcgaaaccaagagaaactaaaaaaatttatgattcggattggagttttcagt ggcctgtatcttgtaccattagtgacacttcttggatgttatgtctatgagcaagtgaat agaattacctgggagataacttgggtctctgatcattgtcgtcagtaccatatcccatgc ccttatcaggcaaaaacaacagctcgaccagaattggctttatttatgataaaatatctg atgacattaattgttggcatctctgctgtcttctgggtcggaagcaaaaagacgtgcaca gaatgggctggtttttttaaacgaaatcgcaagagagatccaatcagtgaaagtcgaaga gtactacaggagtcatgtgagtttttcttaaagcacaattctaaagtgaaacacaaaaag aagcactacaaaccaagttcacataagctgaaagtcatttccaaatccatgggaaccagc acaggagctacagcaaatcatggcgcttctgctgtagcaatcactaaccatgattattta ggacaagaaactcttacagaaatccagacctcaccagaaacatcagtgagagacatggga gcggatggggcaagcactcccaaattaagagaacaggactgtggtgacccttcctcccca gcagcatccagttccaaactctctggggagcaggccaacagaaaaggaaggaaggcggcg aatgtgaacgataagagcagcgtgtctgaaagtgtgcggagtgaaggaagggtaaatcca aaaaatgattttactgaaactgtcccagtgcagagcaacaacttgcagatgcccagttcg tcacagcctagcagcctcaaaggttccacgtcactgcttgttcactcggtttcgggagtt agaaaagagcaggatgcgggcagtcactcagatgcttga

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