KEGG   Loxodonta africana (African savanna elephant): 100655356Help
Entry
100655356         CDS       T04351                                 

Gene name
SETD2
Definition
(RefSeq) histone-lysine N-methyltransferase SETD2 isoform X1
  KO
K11423  histone-lysine N-methyltransferase SETD2 [EC:2.1.1.43]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav00310  Lysine degradation
Brite
KEGG Orthology (KO) [BR:lav00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    100655356 (SETD2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:lav03036]
    100655356 (SETD2)
Enzymes [BR:lav01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.43  histone-lysine N-methyltransferase
     100655356 (SETD2)
Chromosome and associated proteins [BR:lav03036]
 Eukaryotic Type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     100655356 (SETD2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: SRI SET AWS WW
Motif
Other DBs
NCBI-GeneID: 100655356
NCBI-ProteinID: XP_003409942
LinkDB All DBs
Position
Unknown
AA seq 2551 aa AA seqDB search
MLSWLNGNREEENEAKIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSF
SFSLTKKTLQNRFLTALGNEKQNDTPNSPAIPLQADSTPKIKVDIGDTLSTTEESSPPKS
RVELGKIHFKKHLLHVTSRPLLATTTAVTSPPPPTVPLPAVIAESTTVDSPPPSPPPPPP
PPQAKAPSTPAPVTEPVALPRTPIPVLMTAPMPSPVDVAVRALKEPLVTVVSESLEVDTK
QDAVSNSSEERITHTSNEQADIPSQKGDSHIGKEEEIPDSSKSSLGSRKTGSKKKSLQSE
GTFFGSESDEDSVRTSSSQRSHDLKFSASTEKERDSKKSLASLKGEDLGKSSRSKTERDD
KYFSYSKLERDTRYISSRCRSERERRRSRSRSRSDRGSRSSLSYSRSERSHYYDSDRRYH
RNSPYRERTRYSRPYTENRARESSDSEDEYKKTYSRRTSSHSSSYRDLRTSSSYSKSDRD
CKTESSYIETEKRGRYSSKLERESRRTSENEVVKRCSPSNDLGFRRGSSYSKHDNSASRY
KAAPSKPIPKSDKFKNSFCCTELHEGIKQSHSFSLQTPCSKGSELRMINKIPEREKTRSP
SPSNQLNDSPTFKKLDESLIFKSEFIGHDSIKELDSLSKGKHDQLRTYCPVELNINGSPG
AESDLATFCTSKTETVLMSSDDSVTGSEVSPLIKACMRSSNGFQNISRCKEKDLDATCMQ
HSKSESPFRETEPPVSPHQDKLMTLPVKVIDYSKTVVKEPVDMRVSRCKTKDSDIYYTSN
DSNLSLCHSEAENTDPSVTKISSNSFMNVHLESKTVICDNRNLTDQNSKFACEEYKQSVG
STSSASVNHFDDLCQPVGSSSIASPLQSFPPGIKMDSLTLLRCGENTSPALDAVLMSKTS
TEFLKHAGEETIVEVGSRLPDSRRGFSSWENRHNNGLSGKCLQETQEEGNSLLPDRRGRP
EISLDEGGRGHAHTSDDSEVVFSSCDLNLTMEDSDGVTYTLKCDSSGHASEIVSTIHGDY
SGSSESSSDESDSEDTDSDDSSIPRNRLQSIVVVPKNSTLPMEETSPCSSRSSQSYRHYS
DHWEDERLESRRHLYEEKFEVIANKTCPQTEKFFLHKGAEKNSDISFAQSSRKQVDNHLS
EMAHPQSDGVDSTSHTDVKSDPLGHPNSEEIVKVKIASRQQEELPVYSSDDFEDVPNKSR
QQTTYPHRPDSRLGKTELSFSSSCEISLVDGFHSSEELRNLGWDFSQPEKPTTTYQQPDS
SYGACGGHKYQQSAEQYGGTHSYWQGNGYWDPRSAGRPPGTGVVYDRIQGQVPDSLTDDR
EEEENWDQRGGSHFSSQSNKFLQSIQQKDRGSVQAPEISSNSIKDSLAVNEKKDLTKNLE
KNDMKDRGPLKKRRPELESDSESDGELQDRKKVRMEVELGETAVPSGSALVGPSCVMDDF
RDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEI
ACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAARDLPSNT
FVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPN
CETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENR
VSIRAAGGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTC
LKLIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRESNQKLQEEIIKTLEHLPIPTKNM
LEESKVLPVIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPDPSTKLSMEADIETPK
KLMFRRLKIISENSMDSAISDATSELEGKDGKEDLDQLENIPVEEEEELQPQQLLIQQLS
ESRVDGEAAVEVSKLPMSEPEADTEIEPKEGNGTKLEEPIAEETPSQDEEEGVSDVESER
SQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENTIIERGKDAVGFRDQTAAP
KTPNRSRERDPDKQIQNKEKRKRRGSLSPPSSAYERGTKRPDDRYDTPTSKKKVRIKDRN
KLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSPLPYDSLAYNAAHHPFAGYPPGYPMQ
AYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPLVGHSAEPLAAPPPVPVVPHVTTPVE
VSSSQYVAQSDGVVHQDSSVAVLPVPAPGPVQGQNYGVWDSNQQSVSSVQQQYSPAQSQA
AMYYPGQTCPAVYGVAAPYSQSTPPIVQSYAQSSLQYIQGQQIFTAHPQGVVVQPAAAVT
TIVAPGQQQPLQPPEVVVTNNLLDLPPPSPPKPKTIVLPPNWKTARDPEGKIYYYHVITR
QTQWDPPTWESPGDDASLDHEAEMDLGTPTYDENPMKTSKKPKTAEADTSSELAKKSKEV
FRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLARKLTHGVMNKELKYCKNPEDLECN
ENVKHKTKEYIKKYMQKFGALYKPKEDTELE
NT seq 7656 nt NT seq  +upstreamnt  +downstreamnt
atgctttcttggctgaatggcaatagagaagaagaaaatgaggcaaaaattgaaaatgtg
cagaaaacaggtttcatcaaaggaccaatgttcaaaggtgttgcttctagtcgatttttg
cccaaaggcaccaagacaaaagttaatttggaggaacagggacgacagaaggtgtcattc
agcttcagccttacaaagaagactttgcagaacagatttctgactgcacttggaaatgaa
aagcaaaatgatactccaaactccccagctatacctctccaagcagattcgacccctaaa
attaaagtggacattggagatactttatctactacagaagaatcttccccaccaaaatca
agggtggaattgggaaaaattcattttaaaaaacatctacttcatgtaacatctaggccg
ctgctggctactaccacagcagtaacatccccacctcctcccacagtaccattaccagca
gttatagcagaatcaacaactgtagactcaccacccccatctccacctccaccacctcca
cctccccaagccaaagcaccctcaacaccagcaccagtaacagagccagtggccttgcca
cgtacaccaataccagttctgatgacagcaccaatgccctcaccagtagatgtagcagtt
agagccctgaaagaaccactggttacagttgtgtcagagtctttagaagtggacactaag
caggacgctgtatctaatagctcggaagaacgcataactcacacttcgaatgagcaagca
gatattccctcacaaaaaggagattcccatattgggaaggaagaagaaattccagatagt
tctaaaagtagtctgggctctagaaaaacaggttctaagaagaaatctttacaatctgaa
ggcaccttttttggttcagaatctgatgaagattctgtacggacttcctcaagtcagaga
tcacatgatttaaaattttcagcaagcactgaaaaggaaagagattcaaaaaagagctta
gcatctctgaaaggtgaggatttagggaaatcttcacgatctaaaacagagagagatgat
aaatattttagctactcaaaacttgaaagagatactcggtatatatcttcccgatgtaga
tcagagagagagcgaaggcggagcagatctcgttctagatctgatagaggctctagaagt
agtttatcctattctcgatcagaacgatcccattattacgactctgatcgtcgctaccat
aggaactccccttatcgagagaggacacgctattctcgaccatatacagagaacagggca
cgagagagttctgactcagaagatgagtataagaagacgtactcaaggcgcacctcatct
cattcctcctcttacagagacctaaggacatcatcatcctattctaaatctgatcgggac
tgtaaaaccgagtcctcttacatagaaacagagaaaagaggaaggtattcttcaaaacta
gaaagagaatccagaaggacttcagaaaatgaagtagtgaaaaggtgttctccgtctaat
gatctgggattccgacgggggtcatcatattctaagcatgataacagtgcttctcgttat
aaagctgccccttcaaaacctatacccaagtctgataaatttaaaaattctttctgttgt
acagaattacatgaaggaatcaaacagtctcattcttttagtttacagactccttgttca
aaaggtagtgaattaagaatgattaataaaattcctgaaagagaaaagaccaggtctcca
tcaccatcaaatcaattaaatgattcaccaacttttaaaaagctagatgaatcgcttatt
tttaagtctgaatttataggccatgatagtattaaggaattagactctttgtctaaaggg
aagcatgatcaattaagaacttactgtcctgtagaactaaatataaatggatctcctgga
gcagaatctgatttggcaacattttgcacttctaaaactgagactgttttaatgtcttct
gatgatagcgtgactggatcagaggtatcccctttgatcaaagcatgcatgcgttcgtca
aatggatttcagaatattagtagatgtaaagaaaaagacttggatgctacttgcatgcag
catagtaagtcagagagcccgtttagagaaacagaacctccagtgtcaccacaccaggat
aaactcatgacattgccagttaaggtgatagattattccaaaacagtagttaaagaacca
gttgatatgagagtttctcgctgcaaaaccaaagattcagatatatactatacttcaaat
gacagcaacctttctttgtgtcattccgaagctgagaatactgacccttcagttacaaag
atttcttccaatagctttatgaatgttcatttggaatcaaaaacagttatatgtgataat
agaaatctgacagatcagaactcaaagtttgcatgtgaagaatataagcagagtgttggt
agcactagttcagcttctgttaatcattttgatgatttatgccaacctgtagggagttca
agtattgcttcacctcttcagagctttccaccaggaataaaaatggacagtttaactctc
ttgcggtgtggagagaacacatctccagctttggatgctgtgctgatgagtaaaacaagc
acagagtttttaaaacatgcaggggaagaaacaatagtagaagtgggtagccgccttcct
gattcaagaaggggattttcttcctgggaaaacaggcataataatgggttatctgggaaa
tgcttgcaagagactcaagaagaaggaaattccttattacctgatagaagaggaagacca
gaaatctctttagatgaaggaggacgaggacatgcgcatacttctgatgattcagaagtt
gtattttcttcttgtgatttgaatttaaccatggaagacagtgatggtgtaacttatacc
ttaaaatgtgacagtagtggccatgcctcagaaattgtttctactatccatggagattat
tctggttcttctgaaagttcaagtgatgaaagtgattcagaagatacagattctgatgat
agcagtattccaagaaaccgtctccagtccattgtggttgtgccaaagaattctactttg
cctatggaagaaacaagcccttgttcttctcggagcagtcagagttacagacactattcc
gaccactgggaagatgagaggttggagtcaaggagacatttgtatgaggaaaaatttgaa
gttatagcaaataaaacctgtcctcagactgagaagttttttcttcataaaggagcagag
aagaactcagacatttcttttgcacagtccagcagaaaacaagtggataaccacctgtct
gaaatggctcatcctcagagtgacggggttgatagcacaagtcatacagacgtgaaatct
gaccctctaggccatccaaattcggaggaaatagtaaaagtcaaaatagcttctaggcaa
caagaagaactgccagtttattcttctgatgattttgaagatgtcccaaataagtctcgg
caacagactacttaccctcacaggccagatagtagactggggaaaacagagttgagtttt
tcttcctcttgtgagatctctctagttgatggcttccactcatcagaagagctcagaaac
ttagggtgggacttctctcaaccagaaaagcctactaccacgtatcagcaacctgacagc
agctatggagcttgtggtggacacaagtaccagcaaagtgcagaacagtacggtgggacg
catagttactggcaaggcaatggctactgggatccaagatcagcaggcagacctcctgga
actggagttgtgtatgaccgaattcaagggcaggtaccagattccctaacagatgacagg
gaagaggaagagaattgggatcagcgtggtggatcccacttttcaagccagtcaaataaa
ttcctgcagtccattcagcagaaggacagggggtcagtgcaagcacctgagataagcagc
aattccattaaggactctttagctgtgaatgaaaagaaagatcttacaaaaaacttagag
aaaaatgacatgaaagatagagggcctcttaaaaaaaggaggccggaattggagagtgat
tctgaaagcgatggtgagcttcaggatagaaagaaagttagaatggaggtagagctggga
gagacagcagtgccttcaggctctgcactagtgggaccttcctgtgtcatggatgacttc
agggaccctcagcgatggaaggagtgtgccaagcaggggaagatgccttgttacttcgat
cttattgaagaaaatgtttatttaacagaaagaaagaagaataaatcccatcgggacatt
aagcgaatgcagtgtgagtgtacacctctttctaaagatgaaagggctcaaggtgaaata
gcatgcggcgaagattgtcttaatcgtctccttatgattgagtgttcttctcggtgtcca
aatggggattattgttccaatagacggtttcagagaaaacagcatgcagatgtggaagtc
atactcacagaaaagaaaggctggggcttgagagcagccagagatctaccttcgaacacc
tttgtgctggaatattgtggagaggtacttgatcataaagagtttaaagcccgggtgaag
gagtacgcacgaaataaaaacatccactactatttcatggccctgaagaatgatgagata
atagatgccactcagaaaggaaattgctctcgttttatgaatcatagctgtgaaccaaac
tgtgaaacccaaaaatggactgtgaatggacaactgagagttgggttttttaccaccaaa
ctggttccttcaggatcagagttaacatttgactatcagttccaaagatacggaaaagag
gctcagaaatgtttctgcgggtcagctaattgccggggttacctgggaggagagaacaga
gtcagcattcgagcagcaggagggaagatgaagaaggagcgatcccgtaagaaggattca
gtggatggagaactggaagctctgatggaaaatggtgaaggtctctcggataaaaaccag
gtgctcagcttatcccgcctgatggttagaattgaaactttggagcagaaacttacctgt
cttaagctcatacagaacacacactcacagtcctgcctgaaatcctttctggaacgtcat
ggactgtctttgctgtggatctggatggcagagctaggtgatggccgggaaagtaaccag
aagcttcaggaagagattataaagactttggaacacttgcccattcctactaaaaatatg
ttggaagaaagcaaagtacttccagtcattcaacgttggtctcagaccaagactgctgtc
cctcagttgagtgaaggagatgggtattctagtgagaacacatcacgtgctcacacacca
ctcaacacacctgatccttctaccaagttgagcatggaagctgatatagaaacccccaag
aagctcatgtttcgtagacttaaaattataagtgaaaatagcatggacagtgcaatttct
gatgctaccagtgaactagaaggcaaggatggcaaagaggaccttgaccagttagaaaac
atccctgtagaggaagaggaagagttgcagccacaacagctactcatacaacagctgtct
gaatccagagttgatggtgaagctgcagtggaggtcagtaagctccccatgtctgaacca
gaggccgacactgaaatagagcccaaagagggcaatggcacaaaactggaagaacctatt
gctgaggaaacaccatcccaagatgaagaggagggtgtttctgatgtggagagcgaaagg
agccaggaacagccagataaaacagtggatataagtgatttggccaccaagctcctggat
agttggaaagacctaaaggaggtatatcgaattccaaagaaaagtcaaactgaaaaggag
aacacaataattgaacgaggaaaggatgctgttggcttcagagatcaaacggctgcccca
aagactcctaacaggtcaagagagagagacccagacaagcaaattcaaaataaagagaaa
aggaaaagaaggggctccctctcaccaccctcttctgcttatgagcggggaacaaaaagg
ccagatgacagatatgatacaccaacttctaaaaagaaagtacgaattaaagaccgcaat
aaactttctacagaggagcgtcggaagttgtttgagcaagaggtggctcagcgggaggct
caaaaacaacagcagcagatgcagaacctaggaatgacatctcccctgccctatgactct
cttgcatacaatgccgctcatcacccctttgctggctacccaccaggttatcccatgcaa
gcctatgtggatcccagcaaccctaatgctggaaaggtgcttctgcccacacccagcatg
gaccctgtatgttctcctgctccttacgatcatgctcagccattggtgggacactctgca
gaaccccttgctgcccctccaccagtgccagtggtgccacatgtgacaacccctgtggaa
gtttccagttcacagtatgtggcccagagcgatggtgtggtacaccaagactccagtgtt
gccgtcttgccagtgccggccccgggcccagtccagggacagaattacggcgtttgggat
tccaaccagcagtctgtcagcagcgtgcagcagcagtactcccccgcgcagtctcaagca
gccatgtattacccaggtcagacgtgtccggccgtctacggtgtggccgcaccgtactca
cagagcactccaccaatcgtacagagttatgcgcagtcaagtcttcagtacatccaggga
cagcagattttcacagctcacccacaaggagtggtggtacagccagccgcagccgtgact
acaattgttgcaccagggcagcagcagcccttacagccacctgaagtggttgtgacaaat
aatctcctggatctgccacctccttctcctcccaaaccaaaaactattgtcttacctccc
aactggaagacagcccgagatcccgaagggaagatttattactaccatgttatcacaagg
cagactcagtgggatcctcctacttgggaaagccctggagatgatgccagccttgaccat
gaagctgagatggacctaggaaccccaacttatgatgaaaatcccatgaagacctcgaaa
aagcccaagacagcagaagcagacacctccagtgagctggccaaaaaaagcaaagaagta
ttcagaaaagagatgtcccagttcattgtccagtgcctgaacccttaccggaaacctgac
tgcaaagtgggaagaattaccacaactgaagacttcaaacacctggctcgcaagctgaca
catggcgttatgaataaggagctgaagtactgtaagaaccctgaggacctggagtgcaat
gagaatgtgaaacacaaaaccaaggagtacatcaagaagtacatgcagaaatttggggct
ctttacaaacccaaagaggacactgaattggagtga

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