Loxodonta africana (African savanna elephant): 100655386 Help Entry 100655386         CDS       T04351                                  Gene name PRKCE Definition (RefSeq) protein kinase C epsilon type   KO K18050   novel protein kinase C epsilon type [EC:2.7.11.13] Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04022   cGMP-PKG signaling pathway lav04071   Sphingolipid signaling pathway lav04270   Vascular smooth muscle contraction lav04371   Apelin signaling pathway lav04530   Tight junction lav04666   Fc gamma R-mediated phagocytosis lav04750   Inflammatory mediator regulation of TRP channels lav04925   Aldosterone synthesis and secretion lav04930   Type II diabetes mellitus lav04931   Insulin resistance lav04933   AGE-RAGE signaling pathway in diabetic complications lav05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     100655386 (PRKCE)    04071 Sphingolipid signaling pathway     100655386 (PRKCE)    04022 cGMP-PKG signaling pathway     100655386 (PRKCE)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04530 Tight junction     100655386 (PRKCE)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     100655386 (PRKCE)   09152 Endocrine system    04925 Aldosterone synthesis and secretion     100655386 (PRKCE)   09153 Circulatory system    04270 Vascular smooth muscle contraction     100655386 (PRKCE)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100655386 (PRKCE)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     100655386 (PRKCE)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100655386 (PRKCE)    04931 Insulin resistance     100655386 (PRKCE)    04933 AGE-RAGE signaling pathway in diabetic complications     100655386 (PRKCE)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:lav01001]     100655386 (PRKCE) Enzymes [BR:lav01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      100655386 (PRKCE) Protein kinases [BR:lav01001]  Serine/threonine kinases: AGC group   PKC family [OT]    100655386 (PRKCE) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 Pkinase_C FTA2 Kinase-like Kdo Motif Other DBs NCBI-GeneID:  100655386 NCBI-ProteinID:  XP_023412942 LinkDB All DBs Position Unknown AA seq 689 aa AA seqDB search MTVVVVTVVVVLMVVVALVEAEVIVTAMVMVVMMGVVTVVGVVEVMMVVTKMMMEGSLYL HVKVHSTSTGLVLGLTKPQFSLLCSCSSPAPKDNEERVFRERLRPRKRQGAVRRRVHQVN GHKFMATYLRQPTYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIITKCAGLKKQET PDEVGSQRFSVNMPHKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVHRRCETNV APNCGVDARGIAKVLADLGVTPDKITNSGQRRKKLIAGAESPQPASGSSPTEEDRSKSAP TSPCDQEIKELENNIRKALSFDNRGEDHRAAASTDGQLASPGENGEVRQGQAKRLGLDEF NFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARKHPY LTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGV IYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEYGPSV DWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKNPHK RLGCVAAQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNNFDQDFTREEPV LTLVDEAIVKQINQEEFKGFSYFGEDLMP NT seq 2070 nt NT seq  +upstreamnt  +downstreamnt atgacggtggtggtggtgacagtggtggtggtattgatggtggtggtggcgctagtcgag gcagaggtgatagttacggccatggtgatggtggtgatgatgggagtggtgacagtggtg ggggtagtggaggtgatgatggtggttacgaagatgatgatggaggggagtttgtacttg cacgtcaaagtccactcaacgtcaactggtttggttttgggtctaaccaagcctcagttc tctcttctctgctcttgttcttccccagcccctaaggacaatgaagaacgtgtattcagg gaacgcttgcggccgaggaagcggcagggcgccgtcaggcgcagggtccaccaggtcaac ggccacaagttcatggccacctaccttcggcagcccacctactgctcccactgcagagat ttcatctggggtgtcatagggaagcagggataccaatgtcaagtttgcacatgcgtggtc cacaagcggtgtcatgagcttataatcacgaagtgtgctggattaaagaaacaggaaaca cccgatgaggtgggctcccagcggttcagcgtcaacatgccccacaagtttggtatccac aactacaaggtccccaccttctgtgaccactgtgggtccctgctctggggcctcttgcgg cagggcttgcaatgtaaagtctgcaagatgaacgttcaccgtcgctgtgagaccaatgtt gcccccaactgtggagtagatgccagaggaattgccaaggtgctggccgacctcggtgtc actccagacaagatcaccaacagtggccagaggaggaaaaagctcattgctggtgccgag tccccacagcctgcttctggaagctcaccaactgaggaagatcgatccaagtcagcaccc acctccccttgtgaccaggaaataaaagaacttgaaaacaacattcggaaggctttgtca tttgacaatcgtggggaggatcaccgggcggccgcgtccaccgacggccagctggcgagc cctggagagaacggggaagtccggcagggccaggccaagcgcttgggcctggatgagttc aacttcatcaaggtgttgggcaaaggcagctttggcaaggtcatgttggcggaactcaag ggcaaagatgaagtctatgctgtgaaggtcttaaagaaggacgtcatccttcaggatgat gacgtggactgcacgatgacagagaagagaattttggctctggcacggaaacacccgtac ctaacccaactctattgctgcttccagaccaaggaccgcctctttttcgtcatggaatat gtcaatggtggagacctcatgtttcagattcagcgctcccgaaaatttgatgagccccgc tcacggttctatgctgcagaggtcacctcggccctcatgttcctccaccaacatggagtc atctacagggatttgaaactggacaacatcctactagatgcggaaggtcactgcaagctg gctgactttggaatgtgcaaggaagggattctgaacggtgtgacaaccaccacgttctgt gggactcctgactacatagcccccgagatcctacaggagttggagtatggcccttcggtg gactggtgggccctgggggtactgatgtatgagatgatggctgggcagcccccgtttgag gctgacaatgaggacgacctctttgagtccatccttcatgatgacgtgctgtacccggtc tggctcagcaaggaggctgtcagcatcttgaaagcgtttatgaccaagaacccacacaag cgcctgggctgtgtggcagcacagaatggggaggacgccatcaagcagcaccctttcttc aaggagatcgactgggtgcttctggagcagaagaagatcaagccgcccttcaagcctcga atcaaaaccaaaagagacgtcaataactttgaccaagactttacccgggaagagccggta ctcacgctcgtggatgaagcgattgtgaagcagatcaaccaggaggaattcaaaggcttt tcctactttggtgaagacctgatgccgtga

Loxodonta africana (African savanna elephant): 100657357 Help Entry 100657357         CDS       T04351                                  Gene name PRKCQ Definition (RefSeq) protein kinase C theta type   KO K18052   novel protein kinase C theta type [EC:2.7.11.13] Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04064   NF-kappa B signaling pathway lav04140   Autophagy - animal lav04270   Vascular smooth muscle contraction lav04658   Th1 and Th2 cell differentiation lav04659   Th17 cell differentiation lav04660   T cell receptor signaling pathway lav04750   Inflammatory mediator regulation of TRP channels lav04920   Adipocytokine signaling pathway lav04931   Insulin resistance lav05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     100657357 (PRKCQ)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100657357 (PRKCQ)  09150 Organismal Systems   09151 Immune system    04660 T cell receptor signaling pathway     100657357 (PRKCQ)    04658 Th1 and Th2 cell differentiation     100657357 (PRKCQ)    04659 Th17 cell differentiation     100657357 (PRKCQ)   09152 Endocrine system    04920 Adipocytokine signaling pathway     100657357 (PRKCQ)   09153 Circulatory system    04270 Vascular smooth muscle contraction     100657357 (PRKCQ)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100657357 (PRKCQ)  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     100657357 (PRKCQ)   09167 Endocrine and metabolic disease    04931 Insulin resistance     100657357 (PRKCQ)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:lav01001]     100657357 (PRKCQ) Enzymes [BR:lav01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      100657357 (PRKCQ) Protein kinases [BR:lav01001]  Serine/threonine kinases: AGC group   PKC family [OT]    100657357 (PRKCQ) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 Pkinase_C zf-RING_9 Kinase-like Zf_RING zf-RING-like C1_2 APH Motif Other DBs NCBI-GeneID:  100657357 NCBI-ProteinID:  XP_003410641 UniProt:  G3SNX2 LinkDB All DBs Position Unknown AA seq 706 aa AA seqDB search MSPFLRIGLSNFDCGSCQPCQGEAVNPYCAVLVKEYVESENGQMYVQKKPTMYPPWDSTF DAHINKGRVMQIIVKGKNVDLISETTVELYSLAERCRKNNGKTEVWLELKPQGRMLMNAR YFLEMSDTKDLSEFETEGFFALHHRRGAIKQAKVHHVKCHEFTATFFPQPTFCSVCHEFV WGLNKQGYQCRQCNAAIHKKCIDKVIAKCTGSAINSRETMFHKERFKIDMPHRFKVYNYK SPTFCEHCGTLLWGLARQGLKCDACGMNVHHKCQTKVANLCGINQKLMAEALAMIESTQQ ARSLRDTEHIFREGPVEIGLPRSMKEETRLPYLPTPGKREPQGISWDSPMDGMDKVCHPP EPEPSIERPSIHLKLKIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDD DVECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQICHKFDLCR ATFYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDARTNTFC GTPDYIAPEILLGQKYNHSVDWWTFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPR WLEKEAKDLLVKLFVREPEKRLGVRGDIREHPLFQEINWEELERKEIEPPFKPKVKSPYD CSNFDKEFLNEKPRLSFADRALINSMDQNMFRNFSFINPGMERLIS NT seq 2121 nt NT seq  +upstreamnt  +downstreamnt atgtcaccatttcttcgaattggtttgtccaactttgactgtgggtcctgccagccctgt cagggagaagctgttaacccttactgtgctgtgcttgtcaaagaatatgttgaatcagag aatgggcaaatgtatgttcagaagaagccaaccatgtaccccccgtgggacagcactttt gatgcccatataaacaaggggagagtaatgcagatcattgtgaagggcaaaaatgtggac ctaatatctgaaactacagtagagctctactccctggccgagagatgcaggaagaacaat gggaagacagaagtatggttagaactgaaacctcaaggccgaatgctaatgaacgcaaga tactttctggaaatgagtgacacaaaggacttgagtgaatttgagactgaaggcttcttt gctttgcatcaccgtcgaggagccatcaaacaggccaaagtccatcacgtcaagtgtcat gagttcactgccaccttttttccacaacccactttttgctccgtttgccatgagtttgtc tggggtctgaacaaacagggctaccagtgccgacaatgtaatgcagccattcacaagaag tgtatcgataaagttatagctaaatgcacaggatcagctatcaacagtcgagaaaccatg ttccacaaggagcgattcaaaattgacatgccacatcgatttaaagtctacaattacaag agcccaactttctgtgagcactgtgggactctgttgtggggattggcaagacaaggactg aagtgtgatgcatgtggcatgaacgtccatcacaaatgccagacaaaggtggccaacctt tgtggcataaaccagaagctaatggccgaagccctggcaatgattgagagcactcagcag gctcgcagcttaagagacactgagcatatcttcagagaaggtccagttgaaattggtctc ccacgctccatgaaagaagaaacaaggctgccatacttaccaacaccagggaaaagagag cctcaaggaatatcctgggattctccaatggatgggatggataaagtatgccatcctcca gaacctgaaccaagcatagaaagaccgtctatacatctgaaattgaaaattgaggatttt atcttgcacaaaatgttggggaaaggaagttttggcaaggtcttcctagcagagttcaag aaaaccaatcagttttttgcaataaaagccttaaagaaagatgtggtcttgatggatgac gatgtggagtgtacaatggtggagaagagagtcctctcgttggcctgggagcatccattt ttaacgcacatgttttgtacattccagaccaaggaaaacctcttttttgtgatggagtat ctcaacggaggagacttaatgtaccacatccagatctgccacaagtttgatctttgcaga gcgacgttttatgctgctgaaattatccttggtctgcagttcctgcattccaaaggaatt gtctacagggacctgaagctggataatatcctgttagacaaagacggacatatcaaaata gcagactttgggatgtgcaaggagaacatgttaggagatgcgaggacaaacactttctgc ggaactcctgactacatcgccccggagatcttgctgggtcagaaatacaaccattctgtt gactggtggacctttggtgttctcctctatgagatgctcataggtcagtcacctttccat gggcaagatgaagaagagctgttccactccatccgcatggacaatcccttctacccaaga tggcttgagaaggaagccaaagaccttttagtgaagctctttgtgagagaacctgaaaag aggttgggagtgaggggagacatccgcgagcatcctttgtttcaggagatcaattgggaa gagcttgaaagaaaggagattgaaccacctttcaagcctaaagtgaaatcaccatatgac tgcagcaatttcgacaaagaattcctgaatgagaaaccccggctatcattcgctgacaga gcactcatcaacagtatggaccagaacatgttcagaaacttttctttcattaacccaggg atggagaggctgatatcctga

Loxodonta africana (African savanna elephant): 100659245 Help Entry 100659245         CDS       T04351                                  Gene name PRKCD Definition (RefSeq) protein kinase C delta type isoform X2   KO K06068   novel protein kinase C delta type [EC:2.7.11.13] Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04062   Chemokine signaling pathway lav04140   Autophagy - animal lav04270   Vascular smooth muscle contraction lav04621   NOD-like receptor signaling pathway lav04625   C-type lectin receptor signaling pathway lav04666   Fc gamma R-mediated phagocytosis lav04722   Neurotrophin signaling pathway lav04750   Inflammatory mediator regulation of TRP channels lav04912   GnRH signaling pathway lav04915   Estrogen signaling pathway lav04930   Type II diabetes mellitus lav04931   Insulin resistance lav04933   AGE-RAGE signaling pathway in diabetic complications lav05020   Prion disease Brite KEGG Orthology (KO) [BR:lav00001]  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100659245 (PRKCD)  09150 Organismal Systems   09151 Immune system    04621 NOD-like receptor signaling pathway     100659245 (PRKCD)    04625 C-type lectin receptor signaling pathway     100659245 (PRKCD)    04666 Fc gamma R-mediated phagocytosis     100659245 (PRKCD)    04062 Chemokine signaling pathway     100659245 (PRKCD)   09152 Endocrine system    04912 GnRH signaling pathway     100659245 (PRKCD)    04915 Estrogen signaling pathway     100659245 (PRKCD)   09153 Circulatory system    04270 Vascular smooth muscle contraction     100659245 (PRKCD)   09156 Nervous system    04722 Neurotrophin signaling pathway     100659245 (PRKCD)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100659245 (PRKCD)  09160 Human Diseases   09164 Neurodegenerative disease    05020 Prion disease     100659245 (PRKCD)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100659245 (PRKCD)    04931 Insulin resistance     100659245 (PRKCD)    04933 AGE-RAGE signaling pathway in diabetic complications     100659245 (PRKCD)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:lav01001]     100659245 (PRKCD) Enzymes [BR:lav01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      100659245 (PRKCD) Protein kinases [BR:lav01001]  Serine/threonine kinases: AGC group   PKC family [OT]    100659245 (PRKCD) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 Pkinase_C C1_2 Zf_RING zf-RING-like Kinase-like zf-RING_9 PHD Pkinase_fungal APH DUF2318 DZR Motif Other DBs NCBI-GeneID:  100659245 NCBI-ProteinID:  XP_003410103 UniProt:  G5E721 LinkDB All DBs Position Unknown AA seq 676 aa AA seqDB search MAPFLRIAFNSYELGSLQATDEVNQPFCAVKMKEALSTERGKTLVQKKPTMYPEWKSSFD AHIYEGRVIQIVLMRAAEDPVSEVTVGVSVLAERCKKNNGKAEFWLDLQPQAKVLMSVQY FLEDVDCKQSIRGEDEAKFPTMNRRGAIKQAKIHYIKNHEFIATFFGQPTFCSVCKEFVW GLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTAANSRDTMFQKERFNIDMPHRFKVYNYMS PTFCDHCGSLLWGLVKQGLKCADCGMNVHHKCQKKVANLCGINQKLLAEALNQVSQRSSR RSDSGSSEPVGIYQSFEKKPGLSGYDGPDNSGTYGKIWEGSTRCTIENFTFHKVLGKGSF GKVLLAELKGKKEFFAIKALKKDVVLIDDDVECTMVEKRVLALAWENPFLTHLFCTFQTK DHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEILCGLQFLHSKGIIYRDLKLDNVM LDRDGHIKIADFGMCKENVFGENRASTFCGTPDYIAPEILQGLKYSFSVDWWSFGVLLYE MLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDILEKLFERDPPRRLGVTGNIKIH PFFKTINWTLLEKRQVEPPFKPKVKSPGDYSNFDQEFLNEKARLSYSDKNLIDSMDQTAF AGFSFVNPKFEHLLEN NT seq 2031 nt NT seq  +upstreamnt  +downstreamnt atggcgccattcctgcgcatcgctttcaactcctatgagctgggctccctgcaggccacg gatgaggtgaaccagcccttctgtgccgtgaagatgaaggaggcactcagcacagagcga gggaagacactggtgcagaagaagccgaccatgtatcctgagtggaagtcatcgtttgac gcccacatctatgagggccgcgtcatccagattgtgctgatgcgggcggccgaagaccca gtgtccgaggtgaccgtgggcgtgtcggtgctggccgagcgctgcaagaagaacaacggc aaggccgagttctggctggaccttcaaccccaggccaaggtgttgatgtcagtgcaatat ttcttggaagacgtggattgcaagcagtctattcggggtgaggacgaggccaagttccct acaatgaaccgccgtggagccatcaaacaggccaaaatccactacatcaagaaccacgag ttcattgccaccttctttgggcaacccaccttctgttctgtgtgcaaggaattcgtctgg ggtctcaacaagcaaggctacaaatgcaggcaatgcaatgctgctatccacaagaaatgt atcgacaagatcatcggccggtgcactggtaccgcggccaacagccgggacaccatgttc cagaaagaacgcttcaacattgacatgccacaccggttcaaggtgtacaactacatgagc cccaccttctgtgaccactgtggcagtctgctctgggggctggtgaagcaaggattaaag tgcgcagactgtggcatgaatgtacaccacaagtgccagaagaaggtagccaacctctgc ggtatcaaccagaagctcttggctgaggcactgaaccaagtcagccagagatcctcccgc aggtcggattcagggtcttcagagcctgttgggatctaccagagtttcgagaagaagcca gggctttctgggtatgatggcccagacaacagcgggacctatggcaagatctgggagggc agcaccaggtgtaccattgagaacttcaccttccacaaggtcctgggcaaaggcagcttc ggaaaggtgctgcttgcagagctgaagggcaaaaaggaattcttcgctatcaaggccctt aagaaggacgtggttctgattgatgatgacgtggagtgcaccatggtggagaagcgggtg ctggcactcgcatgggagaacccctttctcacccatctgttctgcaccttccagaccaag gaccacctgttttttgtgatggagttcctcaacgggggggacctgatgtaccacatccag gacaaaggccgctttgaactctaccgcgccacgttttatgcagccgagatcctctgtggc ctgcagtttctccacagcaaaggaatcatctacagggacctcaagctggacaatgtgatg ctggaccgggacggccacatcaagattgctgactttggaatgtgcaaggagaacgtattt ggggagaaccgggccagcaccttctgtggcactcctgactacattgctcccgagatcctg cagggcctgaagtactccttctccgtggactggtggtccttcggggtccttctctatgag atgctcattggccagtctcccttccacggtgacgatgaggatgaactcttcgagtccatc cgtgtggacacgccacattacccccgctggattaccaaggagtccaaggacattctggag aagctgtttgaacgggacccacccaggaggctgggagtgacagggaacatcaaaatccac cccttcttcaagaccatcaactggactctgctggagaagcggcaggtggagccacccttc aagcccaaagtgaagtcacctggggactatagcaacttcgaccaggagttcctgaatgag aaggcacggctctcctacagcgacaagaacctcatcgactccatggaccagacggcgttt gctggcttctcctttgtgaaccccaaatttgagcacctcctggaaaattga

Loxodonta africana (African savanna elephant): 100659328 Help Entry 100659328         CDS       T04351                                  Gene name PRKCH Definition (RefSeq) protein kinase C eta type   KO K18051   novel protein kinase C eta type [EC:2.7.11.13] Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04270   Vascular smooth muscle contraction lav04750   Inflammatory mediator regulation of TRP channels Brite KEGG Orthology (KO) [BR:lav00001]  09150 Organismal Systems   09153 Circulatory system    04270 Vascular smooth muscle contraction     100659328 (PRKCH)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100659328 (PRKCH)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:lav01001]     100659328 (PRKCH)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:lav04147]     100659328 (PRKCH) Enzymes [BR:lav01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      100659328 (PRKCH) Protein kinases [BR:lav01001]  Serine/threonine kinases: AGC group   PKC family [OT]    100659328 (PRKCH) Exosome [BR:lav04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    100659328 (PRKCH) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase C1_1 PK_Tyr_Ser-Thr C2 Pkinase_C C1_2 Motif Other DBs NCBI-GeneID:  100659328 NCBI-ProteinID:  XP_023402391 LinkDB All DBs Position Unknown AA seq 697 aa AA seqDB search MSSSTMKFNGYLRVRIGEAVGLQPTRWSLRHSIFKKGYQLLDPYLTVSVDQVRVGQTSTK QKTNKPTYNEEFCANVTDGGHLELAVFHETPLGYDHFVANCTLQFQELLRTAGTSDTFEG WIDLEPEGKVFVVITLAGSFTEATLQRDRIFKHFTRKRQRAMRRRVHQVNGHKFMATYLR QPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQNNINKVDSKIAEQRF GINIPHKFNVHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAV ELAKTLAGMGLQPGNISPTSKLVSRSTLRRQGKESTKEGNGVGVNSSNRFGIDNFEFIRV LGKGSFGKVMLARIKETGDLYAVKVLKKDVILQDDDVECTMTEKRILSLARNHPFLTQLF CCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHEKGIIYRCI YCFLEEQLDPLEIQQEKGLPPCLWVEGWELATAQRPRRPPSCLLPDAHSISNVASLAQIL QEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILK SFMTKNPTMRLGSLPQGGEQAILRHPFFKEIDWAQLNHRQLEPPFRPRIKSREDVSNFDP DFIKEEPVLTPIDEGHLPMINQDEFRNFSYVSPELQL NT seq 2094 nt NT seq  +upstreamnt  +downstreamnt atgtcgtccagcaccatgaagttcaatggctacttgagggtccgcatcggcgaggctgtg gggctgcagcccacccgctggtctctgcgccactcaatcttcaagaagggctaccaactg ctggacccctacctgacggtgagcgtggaccaggtgcgcgtgggccaaaccagcaccaag cagaagaccaacaaacccacgtacaacgaggaattctgcgctaatgttaccgacggcggc cacctcgaacttgctgtctttcacgagacacccctgggttacgaccacttcgtggctaac tgcaccctgcaattccaggagctgctgcgtacggccggcacctcagacaccttcgagggc tggattgatttggagccggaggggaaggtatttgtggtaataaccctagcagggagtttc actgaagctactctccagagagaccgaatcttcaagcattttaccagaaagcgccagagg gctatgcgaaggcgagtccaccaggtcaacggacataagttcatggccacgtacctaagg cagcccacgtactgctctcactgcagggaattcatctggggagtctttgggaaacagggg tatcaatgccaagtgtgcacctgtgttgtccataagcgctgccatcatctaattgttaca gcctgtacttgccaaaacaacattaacaaagtggattcgaagattgctgaacagaggttt ggaatcaacattccacataagttcaatgtccacaactacaaagtgccaacattttgcgat cactgtggctccctgctctgggggataatgcgacaagggcttcagtgtaaaatatgtaaa atgaatgtacatatccgatgtcaagcgaacgtggcccctaattgtggggtgaacgctgtg gagctagccaagacactggccgggatgggtctccaacccggaaatatctctccgacctcg aaacttgtttccagatcgaccttaagacgacaaggaaaggaaagcaccaaagaaggaaat ggggtcggagttaattcttccaaccgatttggtatcgacaactttgagttcatccgagtg ttggggaagggaagttttgggaaggtgatgcttgcaagaataaaagaaactggagacctc tatgccgtgaaagtgctaaagaaggacgtgattctccaggacgatgacgtggaatgcaca atgaccgagaagaggatcctgtctttggctcgcaatcaccccttcctcactcagctgttc tgctgctttcagaccccggatcgtctgttttttgtaatggagtttgtgaatgggggcgac ctgatgttccacatccagaagtctcgtcgctttgatgaagcccgagctcgtttctatgct gcagaaatcatttcagcgctcatgttcttacatgagaaaggaatcatctataggtgcatt tactgtttcttggaggaacaactggatcccctggagatacagcaggagaagggtctgccc ccttgcctttgggtggaaggttgggagcttgccacggcccagagaccaagaagaccccct agttgtttactaccagatgcacatagcatttctaatgttgcctccttggcacagatcctg caggagatgctctacggacctgccgtggattggtgggcaatgggcgtgttgctctacgag atgctctgtgggcatgcaccctttgaggccgagaacgaagatgacctctttgaggccata ctgaatgacgaagtggtctaccctacctggctccatgaagatgccaccgggatcctaaaa tctttcatgaccaagaaccccaccatgcgcttgggcagcctgcctcagggaggtgagcaa gccatcctgagacatcctttctttaaggaaattgactgggcccaactgaaccatcgtcaa ctagagccacctttcagacccagaatcaaatcccgagaagacgtcagtaatttcgaccct gacttcataaaggaagagccagttttaaccccaattgatgagggacatcttcctatgatt aaccaggatgaatttagaaacttttcctacgtatctccagaattgcaactgtaa

Loxodonta africana (African savanna elephant): 100665537 Help Entry 100665537         CDS       T04351                                  Gene name PRKCA Definition (RefSeq) protein kinase C alpha type isoform X1   KO K02677   classical protein kinase C alpha type [EC:2.7.11.13] Organism lav  Loxodonta africana (African savanna elephant) Pathway lav01521   EGFR tyrosine kinase inhibitor resistance lav04010   MAPK signaling pathway lav04012   ErbB signaling pathway lav04014   Ras signaling pathway lav04015   Rap1 signaling pathway lav04020   Calcium signaling pathway lav04066   HIF-1 signaling pathway lav04070   Phosphatidylinositol signaling system lav04071   Sphingolipid signaling pathway lav04072   Phospholipase D signaling pathway lav04150   mTOR signaling pathway lav04151   PI3K-Akt signaling pathway lav04261   Adrenergic signaling in cardiomyocytes lav04270   Vascular smooth muscle contraction lav04310   Wnt signaling pathway lav04360   Axon guidance lav04370   VEGF signaling pathway lav04510   Focal adhesion lav04540   Gap junction lav04613   Neutrophil extracellular trap formation lav04650   Natural killer cell mediated cytotoxicity lav04664   Fc epsilon RI signaling pathway lav04666   Fc gamma R-mediated phagocytosis lav04670   Leukocyte transendothelial migration lav04713   Circadian entrainment lav04720   Long-term potentiation lav04723   Retrograde endocannabinoid signaling lav04724   Glutamatergic synapse lav04725   Cholinergic synapse lav04726   Serotonergic synapse lav04727   GABAergic synapse lav04728   Dopaminergic synapse lav04730   Long-term depression lav04750   Inflammatory mediator regulation of TRP channels lav04911   Insulin secretion lav04912   GnRH signaling pathway lav04916   Melanogenesis lav04918   Thyroid hormone synthesis lav04919   Thyroid hormone signaling pathway lav04921   Oxytocin signaling pathway lav04925   Aldosterone synthesis and secretion lav04926   Relaxin signaling pathway lav04928   Parathyroid hormone synthesis, secretion and action lav04929   GnRH secretion lav04933   AGE-RAGE signaling pathway in diabetic complications lav04935   Growth hormone synthesis, secretion and action lav04960   Aldosterone-regulated sodium reabsorption lav04961   Endocrine and other factor-regulated calcium reabsorption lav04970   Salivary secretion lav04971   Gastric acid secretion lav04972   Pancreatic secretion lav05017   Spinocerebellar ataxia lav05022   Pathways of neurodegeneration - multiple diseases lav05031   Amphetamine addiction lav05032   Morphine addiction lav05143   African trypanosomiasis lav05146   Amoebiasis lav05161   Hepatitis B lav05163   Human cytomegalovirus infection lav05164   Influenza A lav05170   Human immunodeficiency virus 1 infection lav05171   Coronavirus disease - COVID-19 lav05200   Pathways in cancer lav05205   Proteoglycans in cancer lav05206   MicroRNAs in cancer lav05214   Glioma lav05223   Non-small cell lung cancer lav05225   Hepatocellular carcinoma lav05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100665537 (PRKCA)    04012 ErbB signaling pathway     100665537 (PRKCA)    04014 Ras signaling pathway     100665537 (PRKCA)    04015 Rap1 signaling pathway     100665537 (PRKCA)    04310 Wnt signaling pathway     100665537 (PRKCA)    04370 VEGF signaling pathway     100665537 (PRKCA)    04066 HIF-1 signaling pathway     100665537 (PRKCA)    04020 Calcium signaling pathway     100665537 (PRKCA)    04070 Phosphatidylinositol signaling system     100665537 (PRKCA)    04072 Phospholipase D signaling pathway     100665537 (PRKCA)    04071 Sphingolipid signaling pathway     100665537 (PRKCA)    04151 PI3K-Akt signaling pathway     100665537 (PRKCA)    04150 mTOR signaling pathway     100665537 (PRKCA)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     100665537 (PRKCA)    04540 Gap junction     100665537 (PRKCA)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     100665537 (PRKCA)    04650 Natural killer cell mediated cytotoxicity     100665537 (PRKCA)    04664 Fc epsilon RI signaling pathway     100665537 (PRKCA)    04666 Fc gamma R-mediated phagocytosis     100665537 (PRKCA)    04670 Leukocyte transendothelial migration     100665537 (PRKCA)   09152 Endocrine system    04911 Insulin secretion     100665537 (PRKCA)    04929 GnRH secretion     100665537 (PRKCA)    04912 GnRH signaling pathway     100665537 (PRKCA)    04921 Oxytocin signaling pathway     100665537 (PRKCA)    04926 Relaxin signaling pathway     100665537 (PRKCA)    04935 Growth hormone synthesis, secretion and action     100665537 (PRKCA)    04918 Thyroid hormone synthesis     100665537 (PRKCA)    04919 Thyroid hormone signaling pathway     100665537 (PRKCA)    04928 Parathyroid hormone synthesis, secretion and action     100665537 (PRKCA)    04916 Melanogenesis     100665537 (PRKCA)    04925 Aldosterone synthesis and secretion     100665537 (PRKCA)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100665537 (PRKCA)    04270 Vascular smooth muscle contraction     100665537 (PRKCA)   09154 Digestive system    04970 Salivary secretion     100665537 (PRKCA)    04971 Gastric acid secretion     100665537 (PRKCA)    04972 Pancreatic secretion     100665537 (PRKCA)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     100665537 (PRKCA)    04961 Endocrine and other factor-regulated calcium reabsorption     100665537 (PRKCA)   09156 Nervous system    04724 Glutamatergic synapse     100665537 (PRKCA)    04727 GABAergic synapse     100665537 (PRKCA)    04725 Cholinergic synapse     100665537 (PRKCA)    04728 Dopaminergic synapse     100665537 (PRKCA)    04726 Serotonergic synapse     100665537 (PRKCA)    04720 Long-term potentiation     100665537 (PRKCA)    04730 Long-term depression     100665537 (PRKCA)    04723 Retrograde endocannabinoid signaling     100665537 (PRKCA)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100665537 (PRKCA)   09158 Development and regeneration    04360 Axon guidance     100665537 (PRKCA)   09159 Environmental adaptation    04713 Circadian entrainment     100665537 (PRKCA)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100665537 (PRKCA)    05206 MicroRNAs in cancer     100665537 (PRKCA)    05205 Proteoglycans in cancer     100665537 (PRKCA)    05231 Choline metabolism in cancer     100665537 (PRKCA)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     100665537 (PRKCA)    05214 Glioma     100665537 (PRKCA)    05223 Non-small cell lung cancer     100665537 (PRKCA)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     100665537 (PRKCA)    05022 Pathways of neurodegeneration - multiple diseases     100665537 (PRKCA)   09165 Substance dependence    05031 Amphetamine addiction     100665537 (PRKCA)    05032 Morphine addiction     100665537 (PRKCA)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     100665537 (PRKCA)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100665537 (PRKCA)    05161 Hepatitis B     100665537 (PRKCA)    05171 Coronavirus disease - COVID-19     100665537 (PRKCA)    05164 Influenza A     100665537 (PRKCA)    05163 Human cytomegalovirus infection     100665537 (PRKCA)   09174 Infectious disease: parasitic    05146 Amoebiasis     100665537 (PRKCA)    05143 African trypanosomiasis     100665537 (PRKCA)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100665537 (PRKCA)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:lav01001]     100665537 (PRKCA)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:lav04131]     100665537 (PRKCA) Enzymes [BR:lav01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      100665537 (PRKCA) Protein kinases [BR:lav01001]  Serine/threonine kinases: AGC group   PKC family [OT]    100665537 (PRKCA) Membrane trafficking [BR:lav04131]  Endocytosis   Lipid raft mediated endocytosis    Caveolin-mediated endocytosis     100665537 (PRKCA) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C C1_2 Kinase-like APH Motif Other DBs NCBI-GeneID:  100665537 NCBI-ProteinID:  XP_003417343 UniProt:  G3SWW4 LinkDB All DBs Position Unknown AA seq 671 aa AA seqDB search MADVFPSNDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVADEKLRVTVRDA KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNEAFTFKLKPSDKDRRL SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNME LRQKFEKAKLGPAGNKVISPSEDRKPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGT EELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVN GGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIAD FGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYAKSVDWWAYGVLLYEMLAGQPPFDGE DEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRID WEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNP QFMHPILQSAV NT seq 2016 nt NT seq  +upstreamnt  +downstreamnt atggctgacgttttcccgtccaacgactccacggcgtctcaggacgtggccaaccggttc gcccgcaaaggggcgctgaggcagaagaacgtgcacgaggtgaaggaccacaaattcatc gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctgggggttt gggaaacaaggcttccagtgccaagtttgctgttttgtggttcacaagaggtgccatgag tttgttactttttcttgcccgggtgccgataagggacctgacactgacgacccaaggagc aagcacaaatttaaaatccacacttatggaagccccaccttctgtgatcattgtgggtca ttgctgtacggactcattcaccaagggatgaaatgtgacacctgcgacatgaacgttcac aagcagtgtgtaataaatgtccccagcctctgtggaatggatcacacagagaagagaggg cgaatttacctgaaggctgaagttgctgatgagaagctccgcgtcacagtacgagatgca aaaaatctaatccctatggatccaaatgggctttcagatccttacgtgaagctgaaactt attcctgatcctaagaatgaaagcaaacaaaaaaccaaaaccatccgctctacactaaac cctcagtggaatgaggccttcacattcaaattaaagccttcagacaaagaccgacgattg tctgtagaaatctgggactgggatcgaacaacaagaaatgacttcatgggatccctttcc tttggagtttcagagctgatgaagatgccggccagtggatggtacaagttgcttaaccaa gaagaaggtgagtactacaatgtacccattccagaaggggatgaagaaggaaatatggag ctcaggcagaaatttgagaaagccaagcttggccccgctgggaacaaagtgatcagtcct tcagaagataggaaaccttccaacaacctggatcgagtaaaactcacggacttcaatttc ctcatggtcctagggaaggggagttttggaaaggtgatgcttgctgacaggaagggcaca gaagagctgtatgctatcaagattctcaagaaggacgtggtgatccaggatgacgacgtg gagtgcaccatggtggagaagcgagttctggccctgctcgacaagcctccattcctgacg cagctccactcctgcttccagacagtggatcgcctgtacttcgtcatggagtatgtcaac ggtggggacctcatgtaccacattcagcaagtcgggaaatttaaggagccacaagcagta ttctatgcagcagagatttccattggattgttctttcttcataaaagaggaatcatttat agggatctgaaattagataatgtcatgctggattcggaaggacatatcaagattgccgac tttgggatgtgcaaggagcacatgatggatggcgtcacaaccaggaccttctgtgggact ccagattatattgccccggagataatcgcttatcagccgtatgcgaaatccgtggactgg tgggcgtatggcgtcctattatacgaaatgctagctggccagcctccctttgatggcgaa gatgaagatgaactctttcagtctataatggagcataacgtgtcctatccaaaatccttg tccaaggaggccgtttccatctgcaaaggactgatgaccaaacaccccgccaagcggctg ggctgtgggcctgagggtgagagggatgtaagagagcatgccttcttccggagaatcgac tgggagaaactggagaaccgggagatccagccgccgttcaagcccaaagtgtgtggcaaa ggagcagaaaactttgacaagttcttcacgcgagggcagcctgtcttaacgccgcctgac cagctggtcattgctaatatagatcagtctgattttgaagggttctcatatgtcaacccc cagtttatgcaccccatcttacagagcgcagtatga

Loxodonta africana (African savanna elephant): 100671733 Help Entry 100671733         CDS       T04351                                  Gene name PRKCG Definition (RefSeq) LOW QUALITY PROTEIN: protein kinase C gamma type   KO K19663   classical protein kinase C gamma type [EC:2.7.11.13] Organism lav  Loxodonta africana (African savanna elephant) Pathway lav01521   EGFR tyrosine kinase inhibitor resistance lav04010   MAPK signaling pathway lav04012   ErbB signaling pathway lav04014   Ras signaling pathway lav04015   Rap1 signaling pathway lav04020   Calcium signaling pathway lav04066   HIF-1 signaling pathway lav04070   Phosphatidylinositol signaling system lav04071   Sphingolipid signaling pathway lav04150   mTOR signaling pathway lav04270   Vascular smooth muscle contraction lav04310   Wnt signaling pathway lav04370   VEGF signaling pathway lav04510   Focal adhesion lav04540   Gap junction lav04613   Neutrophil extracellular trap formation lav04650   Natural killer cell mediated cytotoxicity lav04666   Fc gamma R-mediated phagocytosis lav04670   Leukocyte transendothelial migration lav04713   Circadian entrainment lav04720   Long-term potentiation lav04723   Retrograde endocannabinoid signaling lav04724   Glutamatergic synapse lav04725   Cholinergic synapse lav04726   Serotonergic synapse lav04727   GABAergic synapse lav04728   Dopaminergic synapse lav04730   Long-term depression lav04750   Inflammatory mediator regulation of TRP channels lav04911   Insulin secretion lav04916   Melanogenesis lav04918   Thyroid hormone synthesis lav04919   Thyroid hormone signaling pathway lav04921   Oxytocin signaling pathway lav04925   Aldosterone synthesis and secretion lav04928   Parathyroid hormone synthesis, secretion and action lav04929   GnRH secretion lav04935   Growth hormone synthesis, secretion and action lav04960   Aldosterone-regulated sodium reabsorption lav04961   Endocrine and other factor-regulated calcium reabsorption lav04970   Salivary secretion lav04971   Gastric acid secretion lav04972   Pancreatic secretion lav05017   Spinocerebellar ataxia lav05022   Pathways of neurodegeneration - multiple diseases lav05031   Amphetamine addiction lav05032   Morphine addiction lav05143   African trypanosomiasis lav05146   Amoebiasis lav05161   Hepatitis B lav05163   Human cytomegalovirus infection lav05170   Human immunodeficiency virus 1 infection lav05171   Coronavirus disease - COVID-19 lav05200   Pathways in cancer lav05205   Proteoglycans in cancer lav05206   MicroRNAs in cancer lav05214   Glioma lav05223   Non-small cell lung cancer lav05225   Hepatocellular carcinoma lav05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100671733 (PRKCG)    04012 ErbB signaling pathway     100671733 (PRKCG)    04014 Ras signaling pathway     100671733 (PRKCG)    04015 Rap1 signaling pathway     100671733 (PRKCG)    04310 Wnt signaling pathway     100671733 (PRKCG)    04370 VEGF signaling pathway     100671733 (PRKCG)    04066 HIF-1 signaling pathway     100671733 (PRKCG)    04020 Calcium signaling pathway     100671733 (PRKCG)    04070 Phosphatidylinositol signaling system     100671733 (PRKCG)    04071 Sphingolipid signaling pathway     100671733 (PRKCG)    04150 mTOR signaling pathway     100671733 (PRKCG)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     100671733 (PRKCG)    04540 Gap junction     100671733 (PRKCG)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     100671733 (PRKCG)    04650 Natural killer cell mediated cytotoxicity     100671733 (PRKCG)    04666 Fc gamma R-mediated phagocytosis     100671733 (PRKCG)    04670 Leukocyte transendothelial migration     100671733 (PRKCG)   09152 Endocrine system    04911 Insulin secretion     100671733 (PRKCG)    04929 GnRH secretion     100671733 (PRKCG)    04921 Oxytocin signaling pathway     100671733 (PRKCG)    04935 Growth hormone synthesis, secretion and action     100671733 (PRKCG)    04918 Thyroid hormone synthesis     100671733 (PRKCG)    04919 Thyroid hormone signaling pathway     100671733 (PRKCG)    04928 Parathyroid hormone synthesis, secretion and action     100671733 (PRKCG)    04916 Melanogenesis     100671733 (PRKCG)    04925 Aldosterone synthesis and secretion     100671733 (PRKCG)   09153 Circulatory system    04270 Vascular smooth muscle contraction     100671733 (PRKCG)   09154 Digestive system    04970 Salivary secretion     100671733 (PRKCG)    04971 Gastric acid secretion     100671733 (PRKCG)    04972 Pancreatic secretion     100671733 (PRKCG)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     100671733 (PRKCG)    04961 Endocrine and other factor-regulated calcium reabsorption     100671733 (PRKCG)   09156 Nervous system    04724 Glutamatergic synapse     100671733 (PRKCG)    04727 GABAergic synapse     100671733 (PRKCG)    04725 Cholinergic synapse     100671733 (PRKCG)    04728 Dopaminergic synapse     100671733 (PRKCG)    04726 Serotonergic synapse     100671733 (PRKCG)    04720 Long-term potentiation     100671733 (PRKCG)    04730 Long-term depression     100671733 (PRKCG)    04723 Retrograde endocannabinoid signaling     100671733 (PRKCG)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100671733 (PRKCG)   09159 Environmental adaptation    04713 Circadian entrainment     100671733 (PRKCG)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100671733 (PRKCG)    05206 MicroRNAs in cancer     100671733 (PRKCG)    05205 Proteoglycans in cancer     100671733 (PRKCG)    05231 Choline metabolism in cancer     100671733 (PRKCG)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     100671733 (PRKCG)    05214 Glioma     100671733 (PRKCG)    05223 Non-small cell lung cancer     100671733 (PRKCG)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     100671733 (PRKCG)    05022 Pathways of neurodegeneration - multiple diseases     100671733 (PRKCG)   09165 Substance dependence    05031 Amphetamine addiction     100671733 (PRKCG)    05032 Morphine addiction     100671733 (PRKCG)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100671733 (PRKCG)    05161 Hepatitis B     100671733 (PRKCG)    05171 Coronavirus disease - COVID-19     100671733 (PRKCG)    05163 Human cytomegalovirus infection     100671733 (PRKCG)   09174 Infectious disease: parasitic    05146 Amoebiasis     100671733 (PRKCG)    05143 African trypanosomiasis     100671733 (PRKCG)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100671733 (PRKCG)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:lav01001]     100671733 (PRKCG) Enzymes [BR:lav01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      100671733 (PRKCG) Protein kinases [BR:lav01001]  Serine/threonine kinases: AGC group   PKC family [OT]    100671733 (PRKCG) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C Kinase-like Motif Other DBs NCBI-GeneID:  100671733 NCBI-ProteinID:  XP_003406900 LinkDB All DBs Position Unknown AA seq 692 aa AA seqDB search MAGLGPGGGDSEGGPRPLFCRKGALRQKVVHEVKSHKFTARFFKQPTFCSHCTDFIWXVL GAQTPVCSFVVHRRCHEFVTFECPGAGKGPQTDDPRNKHKFRLHSYSSPTFCDHCGSLLY GLVHQGMKCSCCEMNVHRRCVRSVPSLCGVDHTERRGRLQLEIRAPTSDEIHVTVGEARN LIPMDPNXLSDPYVELKLIPDPRRKTAQRSHGYRPSLRPPSSRSNLKPGDVERRLSVEVW DWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNVPVADADNCSLLQKFEAC NYPLELYERVRMGPSSSPIPSPSPSPTDSKRCFFGVSPGRLHISDFSFLMVLGKGSFGKV MLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPHFLTQLHSTFQ TPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRDLKLDN VMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEIIAYQPYGKSVDWWSFGVLL YEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGFLTKHPGKRLGSGPDGE PTIRAHGFFRWIDWERLERLEIAPPFRPRPCGRSGENFDKFFTRAAPALTPPDRLVLASI DQADFQGFTYVNPDFVHPDARSPTSPVPVQVM NT seq 2079 nt NT seq  +upstreamnt  +downstreamnt atggcgggcctgggccccggcgggggcgactcagaggggggaccccggcccctgttttgc agaaagggtgctctgaggcagaaggtggttcacgaagtcaagagccacaagttcaccgct cgcttcttcaagcagccaaccttctgcagccactgcaccgacttcatctggtgagtgctg ggggcgcagacgcctgtctgcagctttgtggtgcaccggcgatgccacgaatttgtgacc ttcgagtgtccaggcgctgggaagggcccccagacggacgacccccggaacaagcacaag ttccgcctgcacagctacagcagccccaccttctgcgaccactgtggctccctcctttac gggctggtgcaccagggcatgaaatgctcgtgctgtgagatgaacgtgcaccgtcgctgt gtgcgaagcgtaccctccctgtgtggagtggaccacaccgagcgccgtgggcgcctgcag ctggaaatccgggccccaacttccgatgaaattcacgtcacggtgggcgaggcccgtaac ctcattccaatggaccctaatngtctatcggatccttatgtggaactgaagctcatccca gaccctcggagaaagacagcccagaggagccatggctaccgtccctcactgcgccccccc tcttcccgcagcaacctgaagcccggcgacgtggagcgtcggcttagcgtagaggtgtgg gactgggaccgcacttcccgcaacgacttcatgggggccatgtcctttggggtgtcggag cttctcaaggcgccagtggacggctggtacaagttactgaaccaggaggagggcgaatat tataatgtaccggtggccgacgctgacaactgcagcctcctccagaagtttgaggcctgt aactatcccctggaactatatgagcgggtgcggatgggcccgtcttcctcccccatcccc tctccatcccccagtcccactgactccaaacgctgcttcttcggagtgagcccaggacgc ctgcacatctcagacttcagcttcctcatggttctaggaaaaggcagcttcgggaaggtg atgctggctgagcgcaggggctcagatgagctctacgctatcaagatcctgaagaaggac gtgattgtccaggatgacgacgtggactgcaccctggtggaaaagcgcgtgctggcgcta gggggccgaggcccaggcggccggccccactttctcactcagttgcactccaccttccag accccggatcgcctgtatttcgtgatggagtatgtcactgggggcgacttgatgtaccac attcagcaactgggcaaatttaaggagccccatgcagcgttctacgcagcagaaattgcc attggcctcttcttccttcacaatcagggcatcatctaccgggacctgaaactggacaac gtaatgctagatgcagaaggacacatcaaaattactgacttcggcatgtgcaaggagaac gtcttccctgggaccaccacgcgcaccttctgcgggaccccggactacatagcccccgag atcattgcctaccagccctatgggaagtccgtggattggtggtcctttggggttctactg tatgagatgttggcgggacagcccccttttgacggggaggatgaagaggagctgtttcag gccatcatggaacaaactgtcacctaccccaagtcgctctcccgggaagctgtggcaatc tgcaaggggttcctgaccaagcacccggggaagcgcctgggctctgggccagatggggag cccaccatccgtgctcatggatttttccgctggatcgactgggaacggctggagcggttg gagattgcacctccgttcagaccccgcccgtgcggccgcagtggtgagaacttcgacaaa ttcttcacacgggcagcgccagcgctgacccctccagaccgcctggtcctggccagcatc gaccaggccgactttcagggcttcacctatgtgaaccctgatttcgtgcacccagatgcc cgcagccccaccagcccagtgcccgtgcaagtcatgtaa

Loxodonta africana (African savanna elephant): 100672078 Help Entry 100672078         CDS       T04351                                  Gene name PRKCB Definition (RefSeq) LOW QUALITY PROTEIN: protein kinase C beta type   KO K19662   classical protein kinase C beta type [EC:2.7.11.13] Organism lav  Loxodonta africana (African savanna elephant) Pathway lav01521   EGFR tyrosine kinase inhibitor resistance lav04010   MAPK signaling pathway lav04012   ErbB signaling pathway lav04014   Ras signaling pathway lav04015   Rap1 signaling pathway lav04020   Calcium signaling pathway lav04062   Chemokine signaling pathway lav04064   NF-kappa B signaling pathway lav04066   HIF-1 signaling pathway lav04070   Phosphatidylinositol signaling system lav04071   Sphingolipid signaling pathway lav04150   mTOR signaling pathway lav04270   Vascular smooth muscle contraction lav04310   Wnt signaling pathway lav04370   VEGF signaling pathway lav04510   Focal adhesion lav04540   Gap junction lav04613   Neutrophil extracellular trap formation lav04650   Natural killer cell mediated cytotoxicity lav04662   B cell receptor signaling pathway lav04666   Fc gamma R-mediated phagocytosis lav04670   Leukocyte transendothelial migration lav04713   Circadian entrainment lav04720   Long-term potentiation lav04723   Retrograde endocannabinoid signaling lav04724   Glutamatergic synapse lav04725   Cholinergic synapse lav04726   Serotonergic synapse lav04727   GABAergic synapse lav04728   Dopaminergic synapse lav04730   Long-term depression lav04750   Inflammatory mediator regulation of TRP channels lav04911   Insulin secretion lav04912   GnRH signaling pathway lav04916   Melanogenesis lav04918   Thyroid hormone synthesis lav04919   Thyroid hormone signaling pathway lav04921   Oxytocin signaling pathway lav04925   Aldosterone synthesis and secretion lav04928   Parathyroid hormone synthesis, secretion and action lav04929   GnRH secretion lav04931   Insulin resistance lav04933   AGE-RAGE signaling pathway in diabetic complications lav04935   Growth hormone synthesis, secretion and action lav04960   Aldosterone-regulated sodium reabsorption lav04961   Endocrine and other factor-regulated calcium reabsorption lav04970   Salivary secretion lav04971   Gastric acid secretion lav04972   Pancreatic secretion lav04973   Carbohydrate digestion and absorption lav05017   Spinocerebellar ataxia lav05022   Pathways of neurodegeneration - multiple diseases lav05031   Amphetamine addiction lav05032   Morphine addiction lav05140   Leishmaniasis lav05143   African trypanosomiasis lav05146   Amoebiasis lav05161   Hepatitis B lav05163   Human cytomegalovirus infection lav05164   Influenza A lav05170   Human immunodeficiency virus 1 infection lav05171   Coronavirus disease - COVID-19 lav05200   Pathways in cancer lav05205   Proteoglycans in cancer lav05206   MicroRNAs in cancer lav05214   Glioma lav05223   Non-small cell lung cancer lav05225   Hepatocellular carcinoma lav05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100672078 (PRKCB)    04012 ErbB signaling pathway     100672078 (PRKCB)    04014 Ras signaling pathway     100672078 (PRKCB)    04015 Rap1 signaling pathway     100672078 (PRKCB)    04310 Wnt signaling pathway     100672078 (PRKCB)    04370 VEGF signaling pathway     100672078 (PRKCB)    04064 NF-kappa B signaling pathway     100672078 (PRKCB)    04066 HIF-1 signaling pathway     100672078 (PRKCB)    04020 Calcium signaling pathway     100672078 (PRKCB)    04070 Phosphatidylinositol signaling system     100672078 (PRKCB)    04071 Sphingolipid signaling pathway     100672078 (PRKCB)    04150 mTOR signaling pathway     100672078 (PRKCB)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     100672078 (PRKCB)    04540 Gap junction     100672078 (PRKCB)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     100672078 (PRKCB)    04650 Natural killer cell mediated cytotoxicity     100672078 (PRKCB)    04662 B cell receptor signaling pathway     100672078 (PRKCB)    04666 Fc gamma R-mediated phagocytosis     100672078 (PRKCB)    04670 Leukocyte transendothelial migration     100672078 (PRKCB)    04062 Chemokine signaling pathway     100672078 (PRKCB)   09152 Endocrine system    04911 Insulin secretion     100672078 (PRKCB)    04929 GnRH secretion     100672078 (PRKCB)    04912 GnRH signaling pathway     100672078 (PRKCB)    04921 Oxytocin signaling pathway     100672078 (PRKCB)    04935 Growth hormone synthesis, secretion and action     100672078 (PRKCB)    04918 Thyroid hormone synthesis     100672078 (PRKCB)    04919 Thyroid hormone signaling pathway     100672078 (PRKCB)    04928 Parathyroid hormone synthesis, secretion and action     100672078 (PRKCB)    04916 Melanogenesis     100672078 (PRKCB)    04925 Aldosterone synthesis and secretion     100672078 (PRKCB)   09153 Circulatory system    04270 Vascular smooth muscle contraction     100672078 (PRKCB)   09154 Digestive system    04970 Salivary secretion     100672078 (PRKCB)    04971 Gastric acid secretion     100672078 (PRKCB)    04972 Pancreatic secretion     100672078 (PRKCB)    04973 Carbohydrate digestion and absorption     100672078 (PRKCB)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     100672078 (PRKCB)    04961 Endocrine and other factor-regulated calcium reabsorption     100672078 (PRKCB)   09156 Nervous system    04724 Glutamatergic synapse     100672078 (PRKCB)    04727 GABAergic synapse     100672078 (PRKCB)    04725 Cholinergic synapse     100672078 (PRKCB)    04728 Dopaminergic synapse     100672078 (PRKCB)    04726 Serotonergic synapse     100672078 (PRKCB)    04720 Long-term potentiation     100672078 (PRKCB)    04730 Long-term depression     100672078 (PRKCB)    04723 Retrograde endocannabinoid signaling     100672078 (PRKCB)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100672078 (PRKCB)   09159 Environmental adaptation    04713 Circadian entrainment     100672078 (PRKCB)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100672078 (PRKCB)    05206 MicroRNAs in cancer     100672078 (PRKCB)    05205 Proteoglycans in cancer     100672078 (PRKCB)    05231 Choline metabolism in cancer     100672078 (PRKCB)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     100672078 (PRKCB)    05214 Glioma     100672078 (PRKCB)    05223 Non-small cell lung cancer     100672078 (PRKCB)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     100672078 (PRKCB)    05022 Pathways of neurodegeneration - multiple diseases     100672078 (PRKCB)   09165 Substance dependence    05031 Amphetamine addiction     100672078 (PRKCB)    05032 Morphine addiction     100672078 (PRKCB)   09167 Endocrine and metabolic disease    04931 Insulin resistance     100672078 (PRKCB)    04933 AGE-RAGE signaling pathway in diabetic complications     100672078 (PRKCB)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100672078 (PRKCB)    05161 Hepatitis B     100672078 (PRKCB)    05171 Coronavirus disease - COVID-19     100672078 (PRKCB)    05164 Influenza A     100672078 (PRKCB)    05163 Human cytomegalovirus infection     100672078 (PRKCB)   09174 Infectious disease: parasitic    05146 Amoebiasis     100672078 (PRKCB)    05140 Leishmaniasis     100672078 (PRKCB)    05143 African trypanosomiasis     100672078 (PRKCB)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100672078 (PRKCB)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:lav01001]     100672078 (PRKCB) Enzymes [BR:lav01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      100672078 (PRKCB) Protein kinases [BR:lav01001]  Serine/threonine kinases: AGC group   PKC family [OT]    100672078 (PRKCB) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C C1_2 Kinase-like CEP76-C2 APH Motif Other DBs NCBI-GeneID:  100672078 NCBI-ProteinID:  XP_003418868 LinkDB All DBs Position Unknown AA seq 671 aa AA seqDB search MADSAAGPSLSEGEEGTVRFARKGALWQNNVHEVKNHKFTARFFKQSSFCSHCTDFIWGF GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGS LLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIEREVLIVVVRDA KNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFKFQLKESDKDRRL SVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFKLLSQEEGEYFNVPVPPEGSEANEE LRQKFERAKINQGTKTPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSE RKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVM EYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGVIYRDLKLDNVMLDSEGHI KIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAP FEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFF RYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGF SYTNPEFVINV NT seq 2016 nt NT seq  +upstreamnt  +downstreamnt atggctgactcggctgcggggccatcgctaagcgagggcgaggagggcacggtgcgcttc gcccgcaaaggcgctctctggcagaataacgtgcacgaggtgaagaaccacaaattcacc gcccgcttcttcaagcagtcatctttctgcagtcactgcaccgacttcatctggggcttc ggaaagcaagggttccagtgccaagtctgctgctttgttgtgcacaagcgatgccatgaa tttgttaccttctcctgcccaggagctgacaagggtccagcctctgatgacccccggagc aaacacaaatttaagatccacacatactccagccccacgttctgtgaccactgtgggtcc ctactgtatgggctcatccaccaagggatgaagtgtgacacctgcatgatgaacgtccac aagcgctgcgtgatgaacgtccccagcctgtgcggcacagaccacacggagcgccgcgga cgcatctatatccaggcccacatcgagagggaagtcctcattgtcgttgtaagagatgct aaaaacctcgtacctatggaccccaatggcttgtcagatccctacgtaaaactgaaactg attcctgatcccaaaagtgagagcaagcagaagaccaaaaccatcaagtgctccctcaac cctgagtggaatgagacatttaaattccagctgaaagaatctgacaaagacagaagactg tctgtagagatttgggattgggatctaaccagcaggaatgacttcatgggatcattgtca tttgggatttctgaactgcagaaagctggtgttgatggctggtttaagttactgagccag gaggaaggcgagtacttcaatgtgccagtgccaccagaagggagtgaggccaacgaggaa ctgcggcagaaatttgagagggccaagatcaatcaagggaccaagactccagaagaaaag acaaccaacaccgtatccaaatttgacaacaatggcaacagggaccggatgaaactgact gattttaacttcctgatggtgctggggaaaggcagctttggcaaggtcatgctctccgag cgaaaaggcacggacgagctgtatgccgtgaagatcctgaagaaggatgtggtgatccag gatgacgatgtggagtgcacgatggtggagaagcgggtgctggccctgcccgggaagccc cccttcctgacccagctccactcctgcttccagaccatggaccgcctgtactttgtgatg gagtacgtgaatgggggtgacctgatgtaccacatccaacaagttggccggtttaaggag cctcatgctgtattctacgctgcagagattgccatcggtctgttcttcttacagagcaag ggcgtcatttaccgtgacctgaaacttgacaatgtgatgctggattccgagggccacatc aagatcgctgattttggcatgtgtaaggaaaacatctgggacggggtgacaaccaagacg ttctgtggcactccagactacatcgcccctgagataattgcctatcagccctatgggaag tctgtggattggtgggcatttggagtcctgctgtatgaaatgttggctgggcaggcacct ttcgaaggggaggatgaggatgagctcttccagtctatcatggaacacaacgtggcttat ccaaagtccatgtccaaggaagctgtggccatctgcaaagggctgatgaccaaacaccca ggcaaacgtctgggttgcggacctgaaggtgaacgtgacatcaaagagcatgcatttttc cggtatatcgattgggagaaacttgaacgcaaagagattcagcccccgtacaagccaaaa gccagagacaagcgagacacctccaacttcgacaaagagttcaccagacagcctgtggaa ctcactcccactgataaactcttcatcatgaacttggaccaaaatgagtttgctggcttc tcctatactaatccagaatttgtcattaatgtgtag

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