KEGG   Loxodonta africana (African savanna elephant): 100655802
Entry
100655802         CDS       T04351                                 

Gene name
RAPGEF3
Definition
(RefSeq) LOW QUALITY PROTEIN: rap guanine nucleotide exchange factor 3
  KO
K08014  Rap guanine nucleotide exchange factor 3
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav04015  Rap1 signaling pathway
lav04024  cAMP signaling pathway
lav04072  Phospholipase D signaling pathway
lav04261  Adrenergic signaling in cardiomyocytes
lav04670  Leukocyte transendothelial migration
lav04720  Long-term potentiation
lav04726  Serotonergic synapse
Brite
KEGG Orthology (KO) [BR:lav00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100655802 (RAPGEF3)
   04072 Phospholipase D signaling pathway
    100655802 (RAPGEF3)
   04024 cAMP signaling pathway
    100655802 (RAPGEF3)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    100655802 (RAPGEF3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100655802 (RAPGEF3)
  09156 Nervous system
   04726 Serotonergic synapse
    100655802 (RAPGEF3)
   04720 Long-term potentiation
    100655802 (RAPGEF3)
SSDB
Motif
Pfam: RasGEF DEP RasGEF_N cNMP_binding HTH_Tnp_4
Other DBs
NCBI-GeneID: 100655802
NCBI-ProteinID: XP_023411275
LinkDB
Position
Unknown
AA seq 894 aa
MKVGWPGESRWHLGLAVEASPALGASPAGGLPDVVPEGTLLNMVLRRMHRPRSCSYQLLL
EHRSPSCIQGLRWTPLTDSEESLDFSVSLEQASTERVLRAGKQLHRHLLATCPNLIRDRK
YHLRLYRQCCSGRELVDGILALGLGVHSRSQAVGVCQVLLDEGALSHVKHDWTFQDRDAQ
FYRFPGLEPEPVGAHEMEEELVEAVSLLSQRGPDALLTVALRKPPGQRTDEELDLVIEEV
LNIEARGHLFNSVKRELAAVLLFEPHCKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGR
SPCGGPECVDHWVWLVLQDVEAKTMRLEEHGKVVLVLERTSQGAGPSCPPTPGRNRYTVM
SGTPEKILELLLEAMRPDSSAHDPTETFLSDFLLTHSVFMPSTQLCAALLHHFHAEPAGG
SEQERSTYVCNKRQQILRLVSQWVALYGPVLRTDPVATSFLQKLSDLVSQDARLSNLLKE
QWPERRRHHRLENGYGNASPQMKARNMAVWLAGQDEPLPNSNCAIRAGDKVPYDICRPDH
SVLTLQLPVTASVREVMAALAQEDSWTKEQVLVKVNSAGDAIGLQPDARGVATSLGLNER
LFVVNPQEVHKLTPHPEQLGPTVGSAEGLDLVSAKDLAGQLTDHDWSLFNSIHQVELIHY
VLGPQHLRTVTTANLERFMRRFNELQYWVATELCLCPVPGLRAQLLRKFIKLAAHLKEQK
NLNSFFAVMFGLSNSAVSRLAHTWERLPHKVRKLYSALERLLDPSWNHRVYRLALTKLSP
PVIPFMPLLLKDMTFIHEGNHTLVENLINFEKMRMMARAVRMLHHCRGHSNVPLSPLRSR
VSHLHEDSQASRISTCSEQSLSTRSPASTWAYVQQLKVIDNQRELSRLSREMEP
NT seq 2685 nt   +upstreamnt  +downstreamnt
atgaaggtgggctggccaggagagagccgttggcacttgggcctggctgttgaggcgagc
cctgctctgggagcatcgcctgcggggggcctccctgacgtggtgcctgaggggacgctg
ctcaacatggtgctgaggcggatgcaccggcccagaagctgctcctaccagctgctgttg
gaacaccggagtcccagctgcatccaggggctgcgctggacgccgctcaccgatagcgag
gagtccctggacttcagcgtgagcctggagcaggcctctacggagcgggtgctcagggct
gggaagcagctgcaccgacacctcctggccacctgcccgaacctcatccgagaccgcaag
taccaccttaggctctaccggcaatgctgctctggtcgggagctggtggatgggatcttg
gccctggggcttggggtgcattcccggagccaagccgtaggagtctgccaggtgctgctg
gatgaaggtgccctttcccatgtgaaacacgactggaccttccaggaccgagatgctcaa
ttctaccgttttcctgggctggagccagagcctgtaggagctcatgagatggaggaggag
ctggtggaggctgtgtctctgctctcccaacggggacctgatgccctgctcacagtggcc
cttcgaaagcccccaggtcagcgcacagatgaggagctggacctcgtcatcgaggaggtg
ttgaacatcgaggcccgtggccatcttttcaactcggtgaagcgggagttagcggcagtt
ctgctctttgaaccacactgcaaagcagggaccgtattgttcagccagggggacaagggc
acctcatggtacattatctggaaggggtctgtcaacgtggtgacccatggcaagggaaga
agtccttgtggtgggccagagtgtgttgaccactgggtgtggcttgttctccaggatgtg
gaagccaagaccatgaggctggaagaacatggcaaagtggtgctggtactggagagaacc
tctcagggtgcaggcccttcttgccccccaaccccaggcaggaaccggtatacagtaatg
tctggcaccccagagaagattctagaactgctgttggaggccatgcggcctgattccagt
gctcatgacccaacagagacgttcctcagcgacttcctcctgacccacagtgtcttcatg
cccagcacccagctttgtgcggccctcctgcatcacttccatgcggagcctgcgggaggc
agtgaacaggagcgcagcacctacgtctgcaataagaggcagcagatcctgcggctggtc
agccagtgggtggccctgtatggccctgtgctccgtaccgaccctgtggccaccagcttt
ctccagaaactctcagacctggtgagccaggatgcccggcttagcaacctgctgaaggag
cagtggccagagaggcggcgacaccacaggttggaaaatggctatgggaatgcgtctcct
cagatgaaggcccggaatatggctgtttggctcgccggccaggatgagcccctccccaac
agcaactgtgccatccgagctggggacaaagtcccctacgacatctgccggcccgaccac
tcggtactgaccctgcagctgcctgtgacggcctcggtgagggaggtgatggcagcatta
gcgcaggaggacagctggaccaaggagcaggtgctggtgaaggtcaattctgcaggcgat
gccattggcctgcagccagatgcccgcggcgtggccacgtctctggggctcaatgagcgg
ctctttgttgtcaacccacaggaagtacacaagctgaccccacaccctgagcagttgggg
cccactgtgggctctgctgaggggctggacctggtgagtgccaaggacctggcgggccag
ctaacagaccacgactggagcctcttcaacagcatccaccaggtggagctgatccactat
gtgctgggcccccagcatctgcggaccgtcaccaccgccaacctggagcgcttcatgcgg
cgcttcaatgagctacagtactgggtggccacagagctgtgtctctgtcctgtgcctggc
ctgcgggcccagctgctcaggaagttcatcaagctggctgcccacctcaaggagcaaaag
aatctcaattccttctttgctgtcatgtttggcctcagcaactcagccgtcagccgcctg
gcccacacctgggagcggctgccccacaaggtccggaagctgtactctgccctggagagg
ctgctggacccctcatggaaccaccgagtatatcgactggccctcaccaagctgtcccct
cctgtcatccctttcatgcccctccttctcaaagacatgaccttcatccatgaggggaac
cacacactagtggagaacctcatcaactttgagaagatgcgaatgatggcgagagccgtg
cggatgctgcaccattgccggggccacagcaatgtgcctctctcaccactcagaagccga
gtgtcccacctccacgaggacagccaagcctcaaggatctccacgtgctcagagcagtcc
ctaagcacccggagtccagccagcacctgggcttatgtccagcagctgaaggtcatcgac
aaccagcgggaactctcccgcctctcccgggagatggaaccatga

KEGG   Loxodonta africana (African savanna elephant): 100660747
Entry
100660747         CDS       T04351                                 

Gene name
RAPGEF4
Definition
(RefSeq) rap guanine nucleotide exchange factor 4
  KO
K04351  Rap guanine nucleotide exchange factor 4
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav04015  Rap1 signaling pathway
lav04024  cAMP signaling pathway
lav04072  Phospholipase D signaling pathway
lav04261  Adrenergic signaling in cardiomyocytes
lav04670  Leukocyte transendothelial migration
lav04911  Insulin secretion
Brite
KEGG Orthology (KO) [BR:lav00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100660747 (RAPGEF4)
   04072 Phospholipase D signaling pathway
    100660747 (RAPGEF4)
   04024 cAMP signaling pathway
    100660747 (RAPGEF4)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    100660747 (RAPGEF4)
  09152 Endocrine system
   04911 Insulin secretion
    100660747 (RAPGEF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100660747 (RAPGEF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:lav04131]
    100660747 (RAPGEF4)
Membrane trafficking [BR:lav04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   Rab associated proteins
    100660747 (RAPGEF4)
SSDB
Motif
Pfam: RasGEF DEP cNMP_binding RasGEF_N
Other DBs
NCBI-GeneID: 100660747
NCBI-ProteinID: XP_023398615
LinkDB
Position
Unknown
AA seq 848 aa
MDMAITAFHPGPSGCRTPLIEPHVPLRPANTITKVPSEKILRAGKILRNVILSRAPHMIR
DRKYHLKTYRQCCVGTELVDWMMQQTQCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDK
YLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDD
LEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVN
VVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEAN
TVRLKEHDQDVLVLEKVPAGNRASNQGNSQSQQKYTVMSGTPEKILEHFLETIRLEPALN
EATDSVLNDFVMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYTLNNKKRVIRLVLQ
WAATYGDLLQEDDVAMAFLEEFYVSVSDDARMIAALKEQLPDLEKIVKQILEEAKAPQKK
HKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVAASVKEVISAVADKL
GSGEGLIIVKMSSGGEKVLLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVG
TVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEI
QFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWE
KLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFTD
NLVNFEKMRMIANTARTVRYCRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMS
HRLEPRRP
NT seq 2547 nt   +upstreamnt  +downstreamnt
atggatatggctatcacggcattccaccctggaccttctggttgtaggacacctctcatt
gaacctcacgttcctcttcgtcctgctaacactattaccaaggtcccttcagagaagatc
ctcagggctggaaaaattttacgaaatgtcatcctctctcgagcacctcacatgattaga
gacagaaaataccacctgaagacatatagacaatgctgtgtgggaactgaattggtggac
tggatgatgcagcagactcagtgtgttcactcccggacccaagctgttggcatgtggcaa
gtcctgttagaagatggtgttctcaaccatgtggaccaggagcaccatttccaagacaaa
tatttattttatcgattcctggatgacgagcacgaggatgcccctttgcctactgaggag
gagaagaaggagtgtgatgaggaactccaggacaccatgctgctgctgtcgcagatgggc
cccgacgcccacatgaggatgatcctccgcaaaccacctggccaaaggacggtggatgac
ctagagattatctatgaagagctcctacacattaaagccttgtcccatctttctaccaca
gtgaaacgggagttagcaggtgttctcattttcgagtcccatgccaaaggaggaactgtg
ttgtttaaccagggagaagaaggtacctcctggtacattattctaaaaggatcagtgaat
gtagtcatttatggcaagggtgtggtctgcaccctgcacgagggagatgactttggcaaa
ttagcactagtcaacgatgcccctcgagctgcctctatcgtcttgcgagaagataattgt
catttcttaagagtagacaaggaggatttcaaccggatcctgagggacgtggaggcgaat
acagtcagacttaaagaacatgaccaagacgtcttggtgctggagaaggtcccagcaggg
aacagagcttctaatcaaggaaactcacagtctcagcaaaagtacactgtgatgtcagga
acacctgaaaaaattttagaacattttttagaaacaatacgccttgagccagctttaaat
gaagcaacagattctgttttaaatgattttgttatgatgcactgtgtttttatgccaaat
acccagctttgtccagccctagtggcccattaccacgcacagccttcccaaggtacggaa
caggagaagatggactataccctcaacaacaagaagcgagtcatccgcctggttctacag
tgggctgccacatatggagacctcctacaagaggatgacgtggcaatggctttcctggag
gagttttatgtgtctgtatcagatgatgcccggatgattgctgccctcaaggagcaactg
ccggacttggagaagattgtcaagcaaattttagaagaggcaaaagctccacaaaagaag
cacaaggttcttttacaacagttcaacacaggagatgagagagcccagaaacgccagcct
attcggggctctgatgaagtcctatttaaggtgtattgcatggaccacacctacacaacc
atccgggtgccagtggcagcctcagtgaaggaagtcatcagtgcagttgccgacaaactg
ggctctggagaaggcctgatcatagtcaagatgagttccggcggagagaaggtgctgctc
aaacctaatgatgtttcagtatttacgacactcaccattaacggacgcctgtttgcttgc
ccgcgagagcaattcgattcactgactcccttgccagaacaagaagggccaactgttgga
acagtgggaacttttgaactgatgagctccaaagatttagcataccagatgacgatttat
gactgggaactcttcaactgtgtgcatgagctggagctaatctaccacacatttggaagg
cataattttaaaaagaccacagcaaacttggatttgttcctgaggagatttaatgaaatt
cagttttgggttgtcactgagatttgcctttgttcccagctcagcaagcgtgttcagctc
ttaaaaaaatttattaagatagcagcccactgtaaagagtacaaaaacctgaattccttt
tttgccatcgtcatgggactaagtaacgttgctgtgagccgcctggcactaacgtgggag
aaactgccaagcaagttcaagaagttctatgcagagtttgaaagtttaatggatccttca
agaaaccacagagcgtacaggttgacagtagctaaactggagcctcctctcatccccttc
atgcctttgctcattaaagatatgacatttactcatgaggggaacaagacgttcactgac
aatctagtaaactttgaaaaaatgcgcatgattgcaaatactgccagaacagtgagatac
tgcagaagccaacccttcaatcctgatgcagctcaagctaataagaaccatcaggatgtc
cggagttatgtacggcaattaaatgtgattgacaaccagagaactttatcacagatgtca
catagattagagcctcgtcggccatag

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