Loxodonta africana (African savanna elephant): 100656098 Help Entry 100656098         CDS       T04351                                  Gene name RRAS Definition (RefSeq) ras-related protein R-Ras isoform X3   KO K07829   Ras-related protein R-Ras Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04010   MAPK signaling pathway lav04014   Ras signaling pathway lav04015   Rap1 signaling pathway lav04024   cAMP signaling pathway lav04072   Phospholipase D signaling pathway lav04137   Mitophagy - animal lav04140   Autophagy - animal lav04218   Cellular senescence lav04360   Axon guidance lav04371   Apelin signaling pathway lav04625   C-type lectin receptor signaling pathway lav04810   Regulation of actin cytoskeleton lav05132   Salmonella infection lav05205   Proteoglycans in cancer Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100656098 (RRAS)    04014 Ras signaling pathway     100656098 (RRAS)    04015 Rap1 signaling pathway     100656098 (RRAS)    04371 Apelin signaling pathway     100656098 (RRAS)    04072 Phospholipase D signaling pathway     100656098 (RRAS)    04024 cAMP signaling pathway     100656098 (RRAS)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100656098 (RRAS)    04137 Mitophagy - animal     100656098 (RRAS)   09143 Cell growth and death    04218 Cellular senescence     100656098 (RRAS)   09142 Cell motility    04810 Regulation of actin cytoskeleton     100656098 (RRAS)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     100656098 (RRAS)   09158 Development and regeneration    04360 Axon guidance     100656098 (RRAS)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     100656098 (RRAS)   09171 Infectious disease: bacterial    05132 Salmonella infection     100656098 (RRAS)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04031 GTP-binding proteins [BR:lav04031]     100656098 (RRAS) GTP-binding proteins [BR:lav04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     100656098 (RRAS) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ras Roc Arf GTP_EFTU ATP_bind_1 MMR_HSR1 AAA_22 SRPRB Abhydrolase_4 Ribosomal_S30AE Motif Other DBs NCBI-GeneID:  100656098 NCBI-ProteinID:  XP_003406857 LinkDB All DBs Position Unknown AA seq 218 aa AA seqDB search MSSGAVSGTGRGRPRGGGPGPGDPPPNETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDP TIEDSYTKICTVDGVPARLDILDTAGQEEFGAMREQYMRAGHGFLLVFAINDRQSFNEVS KLFTQILRVKDRDDFPIVLVGNKADLETQRQVPRSEASAFSASHHVAYFEASAKLRLNVD EAFEQLVRAVRKYQEQELPSYPPSAPGKKDGGCPCILL NT seq 657 nt NT seq  +upstreamnt  +downstreamnt atgagcagcggggcggtgtccgggacggggcgggggcggccccggggcggggggccggga cccggggaccccccacccaacgagacacacaagctggtggtcgtgggcggcggcggcgtg ggcaagagcgcgctgaccatccagttcatccagtcctacttcgtgtctgactatgacccc accatcgaggactcctacactaagatctgcacagtggatggcgtccctgcccgactggac atcctggacaccgcaggccaggaggagtttggcgccatgcgggagcaatacatgcgtgct ggccacggcttcctgctggtgtttgccatcaatgaccggcagagtttcaatgaggtgagc aagctgttcacgcaaatcctccgcgtcaaggaccgagatgacttccccatagtgctggtt gggaacaaggcagacctggagacccaacgccaggtcccccgatctgaagcctctgccttc agtgcctcccaccacgtggcctacttcgaggcctctgccaaactgcgcctcaacgtggac gaggcctttgagcagctggttcgggcagtccggaaataccaggaacaagagcttccatcc tatccgcccagtgccccaggcaagaaagatggggggtgcccctgcatcctcctgtag

Loxodonta africana (African savanna elephant): 100659051 Help Entry 100659051         CDS       T04351                                  Gene name NRAS Definition (RefSeq) GTPase NRas   KO K07828   GTPase NRas Organism lav  Loxodonta africana (African savanna elephant) Pathway lav01521   EGFR tyrosine kinase inhibitor resistance lav01522   Endocrine resistance lav04010   MAPK signaling pathway lav04012   ErbB signaling pathway lav04014   Ras signaling pathway lav04015   Rap1 signaling pathway lav04062   Chemokine signaling pathway lav04068   FoxO signaling pathway lav04071   Sphingolipid signaling pathway lav04072   Phospholipase D signaling pathway lav04137   Mitophagy - animal lav04140   Autophagy - animal lav04150   mTOR signaling pathway lav04151   PI3K-Akt signaling pathway lav04210   Apoptosis lav04211   Longevity regulating pathway lav04213   Longevity regulating pathway - multiple species lav04218   Cellular senescence lav04360   Axon guidance lav04370   VEGF signaling pathway lav04371   Apelin signaling pathway lav04540   Gap junction lav04550   Signaling pathways regulating pluripotency of stem cells lav04625   C-type lectin receptor signaling pathway lav04650   Natural killer cell mediated cytotoxicity lav04660   T cell receptor signaling pathway lav04662   B cell receptor signaling pathway lav04664   Fc epsilon RI signaling pathway lav04714   Thermogenesis lav04720   Long-term potentiation lav04722   Neurotrophin signaling pathway lav04725   Cholinergic synapse lav04726   Serotonergic synapse lav04730   Long-term depression lav04810   Regulation of actin cytoskeleton lav04910   Insulin signaling pathway lav04912   GnRH signaling pathway lav04915   Estrogen signaling pathway lav04916   Melanogenesis lav04917   Prolactin signaling pathway lav04919   Thyroid hormone signaling pathway lav04921   Oxytocin signaling pathway lav04926   Relaxin signaling pathway lav04929   GnRH secretion lav04933   AGE-RAGE signaling pathway in diabetic complications lav04935   Growth hormone synthesis, secretion and action lav05010   Alzheimer disease lav05022   Pathways of neurodegeneration - multiple diseases lav05034   Alcoholism lav05160   Hepatitis C lav05161   Hepatitis B lav05163   Human cytomegalovirus infection lav05165   Human papillomavirus infection lav05166   Human T-cell leukemia virus 1 infection lav05167   Kaposi sarcoma-associated herpesvirus infection lav05170   Human immunodeficiency virus 1 infection lav05200   Pathways in cancer lav05203   Viral carcinogenesis lav05205   Proteoglycans in cancer lav05206   MicroRNAs in cancer lav05210   Colorectal cancer lav05211   Renal cell carcinoma lav05213   Endometrial cancer lav05214   Glioma lav05215   Prostate cancer lav05216   Thyroid cancer lav05218   Melanoma lav05219   Bladder cancer lav05220   Chronic myeloid leukemia lav05221   Acute myeloid leukemia lav05223   Non-small cell lung cancer lav05224   Breast cancer lav05225   Hepatocellular carcinoma lav05226   Gastric cancer lav05230   Central carbon metabolism in cancer lav05231   Choline metabolism in cancer lav05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100659051 (NRAS)    04012 ErbB signaling pathway     100659051 (NRAS)    04014 Ras signaling pathway     100659051 (NRAS)    04015 Rap1 signaling pathway     100659051 (NRAS)    04370 VEGF signaling pathway     100659051 (NRAS)    04371 Apelin signaling pathway     100659051 (NRAS)    04068 FoxO signaling pathway     100659051 (NRAS)    04072 Phospholipase D signaling pathway     100659051 (NRAS)    04071 Sphingolipid signaling pathway     100659051 (NRAS)    04151 PI3K-Akt signaling pathway     100659051 (NRAS)    04150 mTOR signaling pathway     100659051 (NRAS)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100659051 (NRAS)    04137 Mitophagy - animal     100659051 (NRAS)   09143 Cell growth and death    04210 Apoptosis     100659051 (NRAS)    04218 Cellular senescence     100659051 (NRAS)   09144 Cellular community - eukaryotes    04540 Gap junction     100659051 (NRAS)    04550 Signaling pathways regulating pluripotency of stem cells     100659051 (NRAS)   09142 Cell motility    04810 Regulation of actin cytoskeleton     100659051 (NRAS)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     100659051 (NRAS)    04650 Natural killer cell mediated cytotoxicity     100659051 (NRAS)    04660 T cell receptor signaling pathway     100659051 (NRAS)    04662 B cell receptor signaling pathway     100659051 (NRAS)    04664 Fc epsilon RI signaling pathway     100659051 (NRAS)    04062 Chemokine signaling pathway     100659051 (NRAS)   09152 Endocrine system    04910 Insulin signaling pathway     100659051 (NRAS)    04929 GnRH secretion     100659051 (NRAS)    04912 GnRH signaling pathway     100659051 (NRAS)    04915 Estrogen signaling pathway     100659051 (NRAS)    04917 Prolactin signaling pathway     100659051 (NRAS)    04921 Oxytocin signaling pathway     100659051 (NRAS)    04926 Relaxin signaling pathway     100659051 (NRAS)    04935 Growth hormone synthesis, secretion and action     100659051 (NRAS)    04919 Thyroid hormone signaling pathway     100659051 (NRAS)    04916 Melanogenesis     100659051 (NRAS)   09156 Nervous system    04725 Cholinergic synapse     100659051 (NRAS)    04726 Serotonergic synapse     100659051 (NRAS)    04720 Long-term potentiation     100659051 (NRAS)    04730 Long-term depression     100659051 (NRAS)    04722 Neurotrophin signaling pathway     100659051 (NRAS)   09158 Development and regeneration    04360 Axon guidance     100659051 (NRAS)   09149 Aging    04211 Longevity regulating pathway     100659051 (NRAS)    04213 Longevity regulating pathway - multiple species     100659051 (NRAS)   09159 Environmental adaptation    04714 Thermogenesis     100659051 (NRAS)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100659051 (NRAS)    05206 MicroRNAs in cancer     100659051 (NRAS)    05205 Proteoglycans in cancer     100659051 (NRAS)    05203 Viral carcinogenesis     100659051 (NRAS)    05230 Central carbon metabolism in cancer     100659051 (NRAS)    05231 Choline metabolism in cancer     100659051 (NRAS)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     100659051 (NRAS)   09162 Cancer: specific types    05210 Colorectal cancer     100659051 (NRAS)    05225 Hepatocellular carcinoma     100659051 (NRAS)    05226 Gastric cancer     100659051 (NRAS)    05214 Glioma     100659051 (NRAS)    05216 Thyroid cancer     100659051 (NRAS)    05221 Acute myeloid leukemia     100659051 (NRAS)    05220 Chronic myeloid leukemia     100659051 (NRAS)    05218 Melanoma     100659051 (NRAS)    05211 Renal cell carcinoma     100659051 (NRAS)    05219 Bladder cancer     100659051 (NRAS)    05215 Prostate cancer     100659051 (NRAS)    05213 Endometrial cancer     100659051 (NRAS)    05224 Breast cancer     100659051 (NRAS)    05223 Non-small cell lung cancer     100659051 (NRAS)   09164 Neurodegenerative disease    05010 Alzheimer disease     100659051 (NRAS)    05022 Pathways of neurodegeneration - multiple diseases     100659051 (NRAS)   09165 Substance dependence    05034 Alcoholism     100659051 (NRAS)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     100659051 (NRAS)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100659051 (NRAS)    05170 Human immunodeficiency virus 1 infection     100659051 (NRAS)    05161 Hepatitis B     100659051 (NRAS)    05160 Hepatitis C     100659051 (NRAS)    05163 Human cytomegalovirus infection     100659051 (NRAS)    05167 Kaposi sarcoma-associated herpesvirus infection     100659051 (NRAS)    05165 Human papillomavirus infection     100659051 (NRAS)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100659051 (NRAS)    01522 Endocrine resistance     100659051 (NRAS)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:lav04131]     100659051 (NRAS)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:lav04147]     100659051 (NRAS)    04031 GTP-binding proteins [BR:lav04031]     100659051 (NRAS) Membrane trafficking [BR:lav04131]  Endocytosis   Macropinocytosis    Ras GTPases     100659051 (NRAS) Exosome [BR:lav04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    100659051 (NRAS)   Exosomal proteins of other body fluids (saliva and urine)    100659051 (NRAS)   Exosomal proteins of breast cancer cells    100659051 (NRAS)   Exosomal proteins of colorectal cancer cells    100659051 (NRAS) GTP-binding proteins [BR:lav04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     100659051 (NRAS) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 FeoB_N Septin ParA Ldh_1_N Motif Other DBs NCBI-GeneID:  100659051 NCBI-ProteinID:  XP_003409648 UniProt:  G3TLL0 LinkDB All DBs Position Unknown AA seq 189 aa AA seqDB search MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL PTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQG CMGLPCVVM NT seq 570 nt NT seq  +upstreamnt  +downstreamnt atgactgagtacaaactggtggtggttggagcaggtggtgttgggaaaagtgcactgaca atccagctaatccagaaccattttgtagatgagtatgatcccaccatagaggattcatac cgaaaacaggtggttatagatggtgaaacctgtctgttggacatactggatacagctgga caagaggagtacagtgccatgagagaccagtacatgaggacaggcgaaggcttcctctgt gtgtttgccatcaataatagcaaatcatttgcagatattaacctctacagggagcagatt aaacgagtaaaagactcagatgatgtacctatggtgctggtgggaaacaagtgtgatttg ccaacaaggacagttgacacaaaacaagcgcatgaactggctaagagttatgggattccg ttcattgaaacctcagccaagaccagacagggtgttgaagatgccttttacacactggta agagaaatacgtcagtaccgaatgaaaaaactcaacagcagcgatgatggaactcaaggt tgtatggggctgccttgtgtggtgatgtaa

Loxodonta africana (African savanna elephant): 100661156 Help Entry 100661156         CDS       T04351                                  Gene name RRAS2 Definition (RefSeq) ras-related protein R-Ras2 isoform X1   KO K07830   Ras-related protein R-Ras2 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04010   MAPK signaling pathway lav04014   Ras signaling pathway lav04024   cAMP signaling pathway lav04072   Phospholipase D signaling pathway lav04137   Mitophagy - animal lav04140   Autophagy - animal lav04218   Cellular senescence lav04371   Apelin signaling pathway lav04625   C-type lectin receptor signaling pathway lav04810   Regulation of actin cytoskeleton lav05205   Proteoglycans in cancer Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100661156 (RRAS2)    04014 Ras signaling pathway     100661156 (RRAS2)    04371 Apelin signaling pathway     100661156 (RRAS2)    04072 Phospholipase D signaling pathway     100661156 (RRAS2)    04024 cAMP signaling pathway     100661156 (RRAS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100661156 (RRAS2)    04137 Mitophagy - animal     100661156 (RRAS2)   09143 Cell growth and death    04218 Cellular senescence     100661156 (RRAS2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     100661156 (RRAS2)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     100661156 (RRAS2)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     100661156 (RRAS2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:lav04147]     100661156 (RRAS2)    04031 GTP-binding proteins [BR:lav04031]     100661156 (RRAS2) Exosome [BR:lav04147]  Exosomal proteins   Exosomal proteins of colorectal cancer cells    100661156 (RRAS2)   Exosomal proteins of bladder cancer cells    100661156 (RRAS2) GTP-binding proteins [BR:lav04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     100661156 (RRAS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ras Roc GTP_EFTU Arf ATP_bind_1 Motif Other DBs NCBI-GeneID:  100661156 NCBI-ProteinID:  XP_023406589 LinkDB All DBs Position Unknown AA seq 180 aa AA seqDB search MAVDVALDHPVESYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQEEFGAMREQYMR TGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQ LARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQEQECPPSPEPTRKEKDKKGCHCVIF NT seq 543 nt NT seq  +upstreamnt  +downstreamnt atggctgttgatgttgcccttgaccacccggttgagtcctattttgtaacggattatgat ccaaccattgaagattcctatacaaagcagtgtgtgattgacgatagagcggcccggcta gatattctggatacagcaggacaagaagagtttggagctatgagagaacagtacatgagg actggagagggtttcctgctggtcttttcagtcacagatagaggcagttttgaagaaatc tataaatttcaaagacagattctcagagtaaaggatcgtgatgagtttccaatgatctta attggtaataaagcagacctggatcatcaaagacaggtgacacaggaagaaggacagcag ttagcacggcaacttaaggtaacatacatggaggcttctgcaaagattaggatgaatgta gatcaagctttccatgagcttgtccgggtgataaggaaatttcaagagcaagaatgtccc ccttctccagaaccaacgcggaaagaaaaagacaagaaaggttgccattgtgtcattttc taa

Loxodonta africana (African savanna elephant): 100661512 Help Entry 100661512         CDS       T04351                                  Gene name KRAS Definition (RefSeq) GTPase KRas isoform X2   KO K07827   GTPase KRas Organism lav  Loxodonta africana (African savanna elephant) Pathway lav01521   EGFR tyrosine kinase inhibitor resistance lav01522   Endocrine resistance lav04010   MAPK signaling pathway lav04012   ErbB signaling pathway lav04014   Ras signaling pathway lav04015   Rap1 signaling pathway lav04062   Chemokine signaling pathway lav04068   FoxO signaling pathway lav04071   Sphingolipid signaling pathway lav04072   Phospholipase D signaling pathway lav04137   Mitophagy - animal lav04140   Autophagy - animal lav04150   mTOR signaling pathway lav04151   PI3K-Akt signaling pathway lav04210   Apoptosis lav04211   Longevity regulating pathway lav04213   Longevity regulating pathway - multiple species lav04218   Cellular senescence lav04360   Axon guidance lav04370   VEGF signaling pathway lav04371   Apelin signaling pathway lav04540   Gap junction lav04550   Signaling pathways regulating pluripotency of stem cells lav04625   C-type lectin receptor signaling pathway lav04650   Natural killer cell mediated cytotoxicity lav04660   T cell receptor signaling pathway lav04662   B cell receptor signaling pathway lav04664   Fc epsilon RI signaling pathway lav04714   Thermogenesis lav04720   Long-term potentiation lav04722   Neurotrophin signaling pathway lav04725   Cholinergic synapse lav04726   Serotonergic synapse lav04730   Long-term depression lav04810   Regulation of actin cytoskeleton lav04910   Insulin signaling pathway lav04912   GnRH signaling pathway lav04914   Progesterone-mediated oocyte maturation lav04915   Estrogen signaling pathway lav04916   Melanogenesis lav04917   Prolactin signaling pathway lav04919   Thyroid hormone signaling pathway lav04921   Oxytocin signaling pathway lav04926   Relaxin signaling pathway lav04929   GnRH secretion lav04933   AGE-RAGE signaling pathway in diabetic complications lav04935   Growth hormone synthesis, secretion and action lav04960   Aldosterone-regulated sodium reabsorption lav05010   Alzheimer disease lav05022   Pathways of neurodegeneration - multiple diseases lav05034   Alcoholism lav05160   Hepatitis C lav05161   Hepatitis B lav05163   Human cytomegalovirus infection lav05165   Human papillomavirus infection lav05166   Human T-cell leukemia virus 1 infection lav05167   Kaposi sarcoma-associated herpesvirus infection lav05170   Human immunodeficiency virus 1 infection lav05200   Pathways in cancer lav05203   Viral carcinogenesis lav05205   Proteoglycans in cancer lav05206   MicroRNAs in cancer lav05210   Colorectal cancer lav05211   Renal cell carcinoma lav05212   Pancreatic cancer lav05213   Endometrial cancer lav05214   Glioma lav05215   Prostate cancer lav05216   Thyroid cancer lav05218   Melanoma lav05219   Bladder cancer lav05220   Chronic myeloid leukemia lav05221   Acute myeloid leukemia lav05223   Non-small cell lung cancer lav05224   Breast cancer lav05225   Hepatocellular carcinoma lav05226   Gastric cancer lav05230   Central carbon metabolism in cancer lav05231   Choline metabolism in cancer lav05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100661512 (KRAS)    04012 ErbB signaling pathway     100661512 (KRAS)    04014 Ras signaling pathway     100661512 (KRAS)    04015 Rap1 signaling pathway     100661512 (KRAS)    04370 VEGF signaling pathway     100661512 (KRAS)    04371 Apelin signaling pathway     100661512 (KRAS)    04068 FoxO signaling pathway     100661512 (KRAS)    04072 Phospholipase D signaling pathway     100661512 (KRAS)    04071 Sphingolipid signaling pathway     100661512 (KRAS)    04151 PI3K-Akt signaling pathway     100661512 (KRAS)    04150 mTOR signaling pathway     100661512 (KRAS)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100661512 (KRAS)    04137 Mitophagy - animal     100661512 (KRAS)   09143 Cell growth and death    04210 Apoptosis     100661512 (KRAS)    04218 Cellular senescence     100661512 (KRAS)   09144 Cellular community - eukaryotes    04540 Gap junction     100661512 (KRAS)    04550 Signaling pathways regulating pluripotency of stem cells     100661512 (KRAS)   09142 Cell motility    04810 Regulation of actin cytoskeleton     100661512 (KRAS)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     100661512 (KRAS)    04650 Natural killer cell mediated cytotoxicity     100661512 (KRAS)    04660 T cell receptor signaling pathway     100661512 (KRAS)    04662 B cell receptor signaling pathway     100661512 (KRAS)    04664 Fc epsilon RI signaling pathway     100661512 (KRAS)    04062 Chemokine signaling pathway     100661512 (KRAS)   09152 Endocrine system    04910 Insulin signaling pathway     100661512 (KRAS)    04929 GnRH secretion     100661512 (KRAS)    04912 GnRH signaling pathway     100661512 (KRAS)    04915 Estrogen signaling pathway     100661512 (KRAS)    04914 Progesterone-mediated oocyte maturation     100661512 (KRAS)    04917 Prolactin signaling pathway     100661512 (KRAS)    04921 Oxytocin signaling pathway     100661512 (KRAS)    04926 Relaxin signaling pathway     100661512 (KRAS)    04935 Growth hormone synthesis, secretion and action     100661512 (KRAS)    04919 Thyroid hormone signaling pathway     100661512 (KRAS)    04916 Melanogenesis     100661512 (KRAS)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     100661512 (KRAS)   09156 Nervous system    04725 Cholinergic synapse     100661512 (KRAS)    04726 Serotonergic synapse     100661512 (KRAS)    04720 Long-term potentiation     100661512 (KRAS)    04730 Long-term depression     100661512 (KRAS)    04722 Neurotrophin signaling pathway     100661512 (KRAS)   09158 Development and regeneration    04360 Axon guidance     100661512 (KRAS)   09149 Aging    04211 Longevity regulating pathway     100661512 (KRAS)    04213 Longevity regulating pathway - multiple species     100661512 (KRAS)   09159 Environmental adaptation    04714 Thermogenesis     100661512 (KRAS)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100661512 (KRAS)    05206 MicroRNAs in cancer     100661512 (KRAS)    05205 Proteoglycans in cancer     100661512 (KRAS)    05203 Viral carcinogenesis     100661512 (KRAS)    05230 Central carbon metabolism in cancer     100661512 (KRAS)    05231 Choline metabolism in cancer     100661512 (KRAS)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     100661512 (KRAS)   09162 Cancer: specific types    05210 Colorectal cancer     100661512 (KRAS)    05212 Pancreatic cancer     100661512 (KRAS)    05225 Hepatocellular carcinoma     100661512 (KRAS)    05226 Gastric cancer     100661512 (KRAS)    05214 Glioma     100661512 (KRAS)    05216 Thyroid cancer     100661512 (KRAS)    05221 Acute myeloid leukemia     100661512 (KRAS)    05220 Chronic myeloid leukemia     100661512 (KRAS)    05218 Melanoma     100661512 (KRAS)    05211 Renal cell carcinoma     100661512 (KRAS)    05219 Bladder cancer     100661512 (KRAS)    05215 Prostate cancer     100661512 (KRAS)    05213 Endometrial cancer     100661512 (KRAS)    05224 Breast cancer     100661512 (KRAS)    05223 Non-small cell lung cancer     100661512 (KRAS)   09164 Neurodegenerative disease    05010 Alzheimer disease     100661512 (KRAS)    05022 Pathways of neurodegeneration - multiple diseases     100661512 (KRAS)   09165 Substance dependence    05034 Alcoholism     100661512 (KRAS)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     100661512 (KRAS)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100661512 (KRAS)    05170 Human immunodeficiency virus 1 infection     100661512 (KRAS)    05161 Hepatitis B     100661512 (KRAS)    05160 Hepatitis C     100661512 (KRAS)    05163 Human cytomegalovirus infection     100661512 (KRAS)    05167 Kaposi sarcoma-associated herpesvirus infection     100661512 (KRAS)    05165 Human papillomavirus infection     100661512 (KRAS)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100661512 (KRAS)    01522 Endocrine resistance     100661512 (KRAS)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:lav04131]     100661512 (KRAS)   09183 Protein families: signaling and cellular processes    04031 GTP-binding proteins [BR:lav04031]     100661512 (KRAS) Membrane trafficking [BR:lav04131]  Endocytosis   Macropinocytosis    Ras GTPases     100661512 (KRAS) GTP-binding proteins [BR:lav04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     100661512 (KRAS) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 MeaB FeoB_N G-alpha ATP_bind_1 Septin NPR1_interact AAA_25 Motif Other DBs NCBI-GeneID:  100661512 NCBI-ProteinID:  XP_003405744 UniProt:  G3U4P8 LinkDB All DBs Position Unknown AA seq 188 aa AA seqDB search MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL PSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKK SKTKCIIM NT seq 567 nt NT seq  +upstreamnt  +downstreamnt atgactgaatataaacttgtggtagttggagctggtggcgtaggcaagagtgccttgacg atacagctaattcagaatcactttgtggatgaatacgaccctacaatagaggattcctac aggaaacaagtagtaattgatggagaaacctgtctcttggatattctcgacacagcaggt caagaggaatacagtgcaatgagggaccagtacatgaggactggggagggctttctttgt gtatttgccataaataatactaaatcatttgaagatattcaccattatagagaacaaata aaaagagttaaagactctgaagatgtacctatggtcctagtaggaaataagtgtgatttg ccttctagaacagtagacacaaaacaggctcaggacttagcaaggagttatggaattcct tttattgaaacatcagcaaagacaagacagggtgttgatgatgccttctatacgttagtt cgagaaattcgaaaacataaagaaaagatgagcaaagatggtaaaaagaagaaaaagaag tcaaagacaaagtgtataattatgtaa

Loxodonta africana (African savanna elephant): 100661766 Help Entry 100661766         CDS       T04351                                  Gene name MRAS Definition (RefSeq) ras-related protein M-Ras isoform X1   KO K07831   Ras-related protein M-Ras Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04010   MAPK signaling pathway lav04014   Ras signaling pathway lav04015   Rap1 signaling pathway lav04072   Phospholipase D signaling pathway lav04137   Mitophagy - animal lav04140   Autophagy - animal lav04218   Cellular senescence lav04371   Apelin signaling pathway lav04625   C-type lectin receptor signaling pathway lav04810   Regulation of actin cytoskeleton lav05205   Proteoglycans in cancer Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100661766 (MRAS)    04014 Ras signaling pathway     100661766 (MRAS)    04015 Rap1 signaling pathway     100661766 (MRAS)    04371 Apelin signaling pathway     100661766 (MRAS)    04072 Phospholipase D signaling pathway     100661766 (MRAS)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100661766 (MRAS)    04137 Mitophagy - animal     100661766 (MRAS)   09143 Cell growth and death    04218 Cellular senescence     100661766 (MRAS)   09142 Cell motility    04810 Regulation of actin cytoskeleton     100661766 (MRAS)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     100661766 (MRAS)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     100661766 (MRAS)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04031 GTP-binding proteins [BR:lav04031]     100661766 (MRAS) GTP-binding proteins [BR:lav04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     100661766 (MRAS) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ras Roc GTP_EFTU Arf RsgA_GTPase MMR_HSR1 ATP_bind_1 Septin AAA_16 MMR_HSR1_Xtn Gtr1_RagA Motif Other DBs NCBI-GeneID:  100661766 NCBI-ProteinID:  XP_003420016 LinkDB All DBs Position Unknown AA seq 208 aa AA seqDB search MATSAVPSDNLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQW AILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFP MILVANKVDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIRQQIP EKSQKKKKKTKWRGDRATGAHKLQCVML NT seq 627 nt NT seq  +upstreamnt  +downstreamnt atggcaaccagcgctgtccccagtgacaacctacccacgtacaagctggtggtggtgggc gatgggggtgtgggcaagagtgccctcaccatccagtttttccagaagatctttgtgcct gactacgatcccactatcgaagactcctacctgaaacatacagagattgacaatcagtgg gccatcttggacgtcctggacacagctgggcaagaggagttcagtgccatgcgagagcag tacatgcggacaggcgacggcttcctcatcgtctactcagtcaccgacaaggccagcttc gagcatgtggaccgcttccaccagctcatccttcgagtcaaggacagggagtcgtttccg atgatccttgtggccaacaaggtcgatttgatgcacttgaggaaaatcaccagggagcaa ggaaaggaaatggcaaccaaacacaatattccgtacatagaaaccagtgccaaggaccca cctctcaatgtcgacaaagccttccatgacctcgttagagtaattaggcaacagattcct gaaaaaagccagaagaagaagaagaaaaccaaatggcggggggaccgggccactggtgcc cacaaactgcagtgtgtgatgttgtga

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