Loxodonta africana (African savanna elephant): 100656286
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Entry
100656286 CDS
T04351
Gene name
TGFBR1
Definition
(RefSeq) TGF-beta receptor type-1 isoform X1
KO
K04674
TGF-beta receptor type-1 [EC:
2.7.11.30
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav04010
MAPK signaling pathway
lav04060
Cytokine-cytokine receptor interaction
lav04068
FoxO signaling pathway
lav04144
Endocytosis
lav04218
Cellular senescence
lav04350
TGF-beta signaling pathway
lav04371
Apelin signaling pathway
lav04380
Osteoclast differentiation
lav04390
Hippo signaling pathway
lav04520
Adherens junction
lav04659
Th17 cell differentiation
lav04926
Relaxin signaling pathway
lav04933
AGE-RAGE signaling pathway in diabetic complications
lav05142
Chagas disease
lav05161
Hepatitis B
lav05166
Human T-cell leukemia virus 1 infection
lav05200
Pathways in cancer
lav05210
Colorectal cancer
lav05212
Pancreatic cancer
lav05220
Chronic myeloid leukemia
lav05225
Hepatocellular carcinoma
lav05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100656286 (TGFBR1)
04350 TGF-beta signaling pathway
100656286 (TGFBR1)
04390 Hippo signaling pathway
100656286 (TGFBR1)
04371 Apelin signaling pathway
100656286 (TGFBR1)
04068 FoxO signaling pathway
100656286 (TGFBR1)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
100656286 (TGFBR1)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100656286 (TGFBR1)
09143 Cell growth and death
04218 Cellular senescence
100656286 (TGFBR1)
09144 Cellular community - eukaryotes
04520 Adherens junction
100656286 (TGFBR1)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
100656286 (TGFBR1)
09152 Endocrine system
04926 Relaxin signaling pathway
100656286 (TGFBR1)
09158 Development and regeneration
04380 Osteoclast differentiation
100656286 (TGFBR1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100656286 (TGFBR1)
09162 Cancer: specific types
05210 Colorectal cancer
100656286 (TGFBR1)
05212 Pancreatic cancer
100656286 (TGFBR1)
05225 Hepatocellular carcinoma
100656286 (TGFBR1)
05226 Gastric cancer
100656286 (TGFBR1)
05220 Chronic myeloid leukemia
100656286 (TGFBR1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
100656286 (TGFBR1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100656286 (TGFBR1)
05161 Hepatitis B
100656286 (TGFBR1)
09174 Infectious disease: parasitic
05142 Chagas disease
100656286 (TGFBR1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lav01001
]
100656286 (TGFBR1)
Enzymes [BR:
lav01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
100656286 (TGFBR1)
Protein kinases [BR:
lav01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR1 family [OT]
100656286 (TGFBR1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
TGF_beta_GS
Pkinase_fungal
APH
Activin_recp
FTA2
Motif
Other DBs
NCBI-GeneID:
100656286
NCBI-ProteinID:
XP_023400872
LinkDB
All DBs
Position
Unknown
AA seq
434 aa
AA seq
DB search
MCIAENDLIPRDRPFVCAPSSRTGSATTTYCCKQDHCNKIELPTPVKPTSGLGPVELAAV
IAGPVCFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDMTTSGS
GSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIY
QTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALST
ASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAP
NHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYY
DLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIK
KTLSQLSQQEGIKM
NT seq
1305 nt
NT seq
+upstream
nt +downstream
nt
atgtgtatagcggaaaacgacttaattcctcgagacaggccatttgtatgtgcgccctct
tcaagaactgggtctgcaactacaacatattgctgcaagcaggatcattgcaataaaata
gaactcccaactcctgtaaagccgacatccggccttggtcccgttgaactggcagctgtc
atcgctggaccagtgtgcttcgtctgcatctcgctcatgttgatggtctatatctgccat
aaccgcactgtcattcaccatcgagtgcccaacgaagaggatccttcattagatcgccct
tttatttcagagggtaccacattgaaagatttaatttatgatatgacaacatcaggttct
ggatcaggtttaccattgcttgttcagagaacaatcgcaagaactattgtattacaagaa
agcattggcaaaggtcgatttggagaagtttggcgaggaaagtggcggggagaagaagtc
gctgttaaaatattttcctctagagaagaacgctcatggtttcgcgaggcagagatttat
caaactgtaatgttacgtcatgaaaacatcctgggatttatagcagcagacaataaagac
aatggcacatggacccagctctggttggtctcagattatcatgagcatggatctcttttt
gattacttgaataggtacacagttaccgtggaaggaatgataaaactcgctctgtccaca
gcaagtgggcttgcgcatcttcacatggagattgttggtacccaaggaaaaccagccatt
gctcatagagatttgaaatcaaagaatatcttggtaaagaagaatggaacttgctgtatt
gcagacttgggactggcagtaagacacgattcagccactgatacaattgatattgctcca
aatcacagagtgggaacaaaaaggtacatggcccctgaagttctagatgattccataaat
atgaaacactttgaatccttcaaacgtgctgacatctatgcaatgggcttagtattctgg
gaaattgctcgacgatgttccattggtggaattcacgaagattaccagctgccttattat
gatcttgtaccttctgatccatcagttgaagaaatgagaaaagttgtttgtgaacagaag
ttaaggccaaatattccaaacagatggcaaagctgtgaagccttgagagtaatggctaaa
atcatgagagaatgttggtatgccaacggagcagccagacttacagctttgcggattaag
aaaacgttatcacaactcagtcaacaggaaggcatcaaaatgtaa
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