Loxodonta africana (African savanna elephant): 100658069
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Entry
100658069 CDS
T04351
Definition
(RefSeq) LOW QUALITY PROTEIN: steroid 21-hydroxylase
KO
K00513
steroid 21-monooxygenase [EC:
1.14.14.16
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav00140
Steroid hormone biosynthesis
lav01100
Metabolic pathways
lav04925
Aldosterone synthesis and secretion
lav04927
Cortisol synthesis and secretion
lav04934
Cushing syndrome
Module
lav_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
100658069
09150 Organismal Systems
09152 Endocrine system
04925 Aldosterone synthesis and secretion
100658069
04927 Cortisol synthesis and secretion
100658069
09160 Human Diseases
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100658069
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450 [BR:
lav00199
]
100658069
Enzymes [BR:
lav01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14.16 steroid 21-monooxygenase
100658069
Cytochrome P450 [BR:
lav00199
]
Cytochrome P450, animal type
CYP21 family
100658069
BRITE hierarchy
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Ortholog
Paralog
GFIT
Motif
Pfam:
p450
Motif
Other DBs
NCBI-GeneID:
100658069
NCBI-ProteinID:
XP_023397121
LinkDB
All DBs
Position
Unknown
AA seq
494 aa
AA seq
DB search
MLLLGLLLLLPLLAAARLLWGWWMLRTLRLPPLVPGFLHLLQPNLPFYLLGLPQKLGPVY
XALGLQEVVVLNSKRAIEEAMVKKWVDFAGRPQTPSYKLVSLDYQDVSVGDYSLLWKAHK
KLTRSALLLGIRSSMEPLVQELTQEFCERMRAQAGAPVAIYKELSLLTCTIICYLIFGDK
QEDSLVRAFHDCVQDLLSTWDHWSIQILDIVPFLRVLPTPGLWRMKRALEKRDHMVKEQL
RRHKDSLVAGQCRDMMDYMLQGLRKHSMEEGSTGELRESHVHMSTVDLFIGGTDTTATTL
SWAVTFLLHHPEIQQRLQEELDRELGPSTSNSWIKYKDRARLPLLNATIEEVLRLRSSVP
LALPHRTTRPSSILGYDIPEGMVVIPNLLGSHLDETVWERPHEFWPERFLEPGAHPSALP
FGCGARVCLGEPLARLEIFVVLMQLLRAFTLLPAAGALPSLQPRPHCAVSLQTQPFQVRL
QPRGAGAPGLGESQ
NT seq
1485 nt
NT seq
+upstream
nt +downstream
nt
atgctgctcctggggctgctgctgctgctgcccctgctggctgctgcccgcctgctatgg
ggctggtggatgcttaggaccctccgcctcccaccgctcgtcccgggcttcctgcacctg
ctgcagcccaatcttcccttctacctgcttggcctgcctcagaaactcgggcctgtctac
nntgccctggggctgcaagaggtggtggtgctgaactccaagagggccattgaggaggcc
atggtcaagaagtgggtggactttgctggcagaccccagacaccatcctataagctggtg
tctctggactaccaggatgtgtcagtaggggactactccctgctctggaaggcccacaag
aagctcacccgctcagctctgctgctgggtatccgaagctccatggagcctcttgtgcag
gagctgacccaggagttctgtgagcgcatgagagcccaggctggtgcccccgtggccatc
tataaggaactatccttgctcacctgtaccatcatctgctacctcatttttggagacaag
caggaggactctctagtgcgtgcctttcatgactgcgtccaggacttgttaagtacctgg
gaccactggtccatccaaattttggacattgttccctttctcagggttcttcccacccca
ggtctgtggaggatgaagcgggccttggagaagagagaccacatggtgaaggagcagctg
aggcggcacaaggacagcctggtggccggccagtgcagggacatgatggactacatgctg
caagggctgaggaagcacagcatggaagagggcagcacaggggagctccgtgaaagccac
gtgcacatgtctacagtggacctgttcatcggtggcacggacaccacagcaaccaccctc
tcctgggcagtgacgttcttgcttcaccaccctgagattcagcagcgactgcaggaggag
ctggatcgtgagctgggccctagtacctcgaactcctggatcaagtataaggatcgtgcg
cggctgcccttgctcaacgctaccatcgaggaggtgcttcgcctgcggtcctctgtgccc
ctggccttgccccaccgcaccacgcggcccagcagcatcctgggctacgacattcccgag
ggcatggtcgtcatccccaacctcctaggctcccatctcgacgagacggtctgggagcgg
ccgcacgagttctggcccgagcgcttcctggagcctggcgcgcaccccagcgcgctgccc
ttcggttgcggcgcgcgcgtgtgcctaggggagccgctggcgcgcctcgagatctttgtg
gtgctgatgcagctgctccgggctttcacgctgctgccggccgccggcgccctgccctcg
ctgcagccccggccccactgtgccgtctccctccagacgcagcctttccaggtgcggctg
cagccccggggcgccggtgcacctggcctgggagagagccaatga
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