Loxodonta africana (African savanna elephant): 100659992
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Entry
100659992 CDS
T04351
Gene name
CACNA1D
Definition
(RefSeq) LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1D
KO
K04851
voltage-dependent calcium channel L type alpha-1D
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav04010
MAPK signaling pathway
lav04020
Calcium signaling pathway
lav04022
cGMP-PKG signaling pathway
lav04024
cAMP signaling pathway
lav04218
Cellular senescence
lav04260
Cardiac muscle contraction
lav04261
Adrenergic signaling in cardiomyocytes
lav04270
Vascular smooth muscle contraction
lav04530
Tight junction
lav04713
Circadian entrainment
lav04723
Retrograde endocannabinoid signaling
lav04724
Glutamatergic synapse
lav04725
Cholinergic synapse
lav04726
Serotonergic synapse
lav04727
GABAergic synapse
lav04728
Dopaminergic synapse
lav04911
Insulin secretion
lav04912
GnRH signaling pathway
lav04921
Oxytocin signaling pathway
lav04924
Renin secretion
lav04925
Aldosterone synthesis and secretion
lav04927
Cortisol synthesis and secretion
lav04929
GnRH secretion
lav04930
Type II diabetes mellitus
lav04934
Cushing syndrome
lav04935
Growth hormone synthesis, secretion and action
lav04973
Carbohydrate digestion and absorption
lav05010
Alzheimer disease
lav05020
Prion disease
lav05022
Pathways of neurodegeneration - multiple diseases
lav05031
Amphetamine addiction
lav05410
Hypertrophic cardiomyopathy
lav05412
Arrhythmogenic right ventricular cardiomyopathy
lav05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100659992 (CACNA1D)
04020 Calcium signaling pathway
100659992 (CACNA1D)
04024 cAMP signaling pathway
100659992 (CACNA1D)
04022 cGMP-PKG signaling pathway
100659992 (CACNA1D)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
100659992 (CACNA1D)
09144 Cellular community - eukaryotes
04530 Tight junction
100659992 (CACNA1D)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
100659992 (CACNA1D)
04929 GnRH secretion
100659992 (CACNA1D)
04912 GnRH signaling pathway
100659992 (CACNA1D)
04921 Oxytocin signaling pathway
100659992 (CACNA1D)
04935 Growth hormone synthesis, secretion and action
100659992 (CACNA1D)
04924 Renin secretion
100659992 (CACNA1D)
04925 Aldosterone synthesis and secretion
100659992 (CACNA1D)
04927 Cortisol synthesis and secretion
100659992 (CACNA1D)
09153 Circulatory system
04260 Cardiac muscle contraction
100659992 (CACNA1D)
04261 Adrenergic signaling in cardiomyocytes
100659992 (CACNA1D)
04270 Vascular smooth muscle contraction
100659992 (CACNA1D)
09154 Digestive system
04973 Carbohydrate digestion and absorption
100659992 (CACNA1D)
09156 Nervous system
04724 Glutamatergic synapse
100659992 (CACNA1D)
04727 GABAergic synapse
100659992 (CACNA1D)
04725 Cholinergic synapse
100659992 (CACNA1D)
04728 Dopaminergic synapse
100659992 (CACNA1D)
04726 Serotonergic synapse
100659992 (CACNA1D)
04723 Retrograde endocannabinoid signaling
100659992 (CACNA1D)
09159 Environmental adaptation
04713 Circadian entrainment
100659992 (CACNA1D)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100659992 (CACNA1D)
05020 Prion disease
100659992 (CACNA1D)
05022 Pathways of neurodegeneration - multiple diseases
100659992 (CACNA1D)
09165 Substance dependence
05031 Amphetamine addiction
100659992 (CACNA1D)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100659992 (CACNA1D)
05412 Arrhythmogenic right ventricular cardiomyopathy
100659992 (CACNA1D)
05414 Dilated cardiomyopathy
100659992 (CACNA1D)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
100659992 (CACNA1D)
04934 Cushing syndrome
100659992 (CACNA1D)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
lav04040
]
100659992 (CACNA1D)
Ion channels [BR:
lav04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
100659992 (CACNA1D)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
CAC1F_C
GPHH
Ca_chan_IQ
PKD_channel
Rer1
Motif
Other DBs
NCBI-GeneID:
100659992
NCBI-ProteinID:
XP_023403870
LinkDB
All DBs
Position
Unknown
AA seq
2168 aa
AA seq
DB search
MMMMMMMKKMQHQRQQADHANEANYARGTRLPLSGEGPTSQPNSSKQTVLSWQAAIDAAR
QAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACIS
IVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKII
AYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSGGKSGGFDVKALRA
FRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKTC
FFADSDIVAEEDPAPCAFSGNGRQCTANDTECKSGWVGPNGGITNFDNFAFAMLTVFQCI
TMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGD
FQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGKRNTSMPTSETESVNTENVSG
EGENQGCCASLWCWWKRRGAAKAGPSGCRRWSGLLSGFRSRRWRRWNRFSRRRCRAAVKS
VTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAY
FVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVAS
LLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQIL
TGEDWNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGWSFCIYFIILFIGGNYIL
LNVFLAIAVDNLADAESLNTAQKEEAEEKERKKIARKESLENKKNNKPEVNQIANSDNKV
TIDDYREEDEDKDPYPPCDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIIPIPEG
SAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFD
YAFTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKIL
RVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYR
CTDEAKSNPEECRGLFILYKDGEVDNPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGW
PALLYKAIDSNGENVGPIYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEY
KNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLA
MQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKHYFTDAWNTFDALIVVGSVVD
IAITEVNPTESENVPVPTAAPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTF
IKSFQALPYVALLIAMLFFIYAVIGMQMFGKVALRDNNQINRNNNFQTFPQAVLLLFRCA
TGEAWQEIMLACLPGKLCDPESDYNPGEEYTCGSNFAIVYFISFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQHPXGFGKLCP
HRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEVVPPAGDDEVTVGKFYATFL
IQDYFRKFKKRKEQGLVGKHPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEEAN
REEEDLFKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSIPPASDTEKPLFPPA
GNSVCHNHHNHNSIGKQIPNSTNANLNNANMSKAAHGKRPSIANLEHVSDNGHHSSHKHD
REPQRRSSFKRTRYYETYVRSDSGDEQLPTICWEDSEIHGYFQDPRCLGEQEYFSSEEYY
EDDSSPTRSRHNNGYYNRYPGSSLDFERPRGYHHPQGFLEDDDSPVCYDRRSPRRRLLPP
TPTSHRRSSFNFECLRRQGSQEEVPPSPAFPHRTALPLHLMQQQIMAVAGLDSSKVQKYS
PSHSTRSWATPPATPPYQDWTPCYTPLIQVERSESLDQVNGSLPSLHRSSWYTDEPGIAY
RTFTPASLTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYARDPKFVSATKHEIADACD
LTIDEMESAASHLLNGNVSPRANGDVGPVSHQQDYELQDFGSGYSDEEPDPGRYEEDLAD
EMICITTL
NT seq
6507 nt
NT seq
+upstream
nt +downstream
nt
atgatgatgatgatgatgatgaaaaaaatgcagcatcaacggcagcaagcggaccacgcg
aatgaggcaaactatgcaagaggcaccagactccctctttctggtgaaggaccaacttct
cagccgaatagctccaagcagactgtcctgtcttggcaagctgcaatcgatgctgctaga
caggccaaggctgcccaaactatgagcacctccgcgcctccacctgtaggatctctctcc
caaagaaaacgtcagcaatacgccaagagcaaaaaacagggtaactcgtccaacagccga
cctgcccgtgcccttttctgtttatcactcaataaccccatccgaagagcctgcattagt
atagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgtgtg
gccttagctatttacatcccattccctgaagatgattctaattcaaccaaccataacttg
gaaaaagtagaatatgccttcctgattatttttacagtcgagacatttttgaagattata
gcttatggattattgctacatcctaatgcttatgttaggaatggatggaatttattggat
tttgttatagtaatagtaggattgtttagtgtaattttggaacaattaaccaaagaaaca
gaaggcggtaaccactctggtggcaaatcaggaggctttgatgtcaaagccctccgcgcc
tttcgagtgttacgaccacttcgactagtatcaggagtgcccagtttacaagttgtcctg
aactccattataaaagccatggttcccctccttcacatagcccttttggtattatttgta
atcataatctatgctattataggattggaactttttattggaaaaatgcacaaaacatgc
ttttttgctgactcagatatcgtagctgaagaggacccagcgccatgtgcgttctcaggg
aatggacgccagtgtaccgccaatgacacagagtgtaagagtggctgggttggcccaaat
ggaggcatcacaaactttgataactttgcctttgccatgctcaccgtgtttcagtgtatc
accatggagggctggacagacgtgctctactggatgaatgatgctatgggatttgaattg
ccctgggtgtattttgtcagtctcgtcatctttgggtcatttttcgtactaaatcttgta
cttggtgtattgagcggagaattttcaaaggaaagagagaaggctaaagcacggggagat
ttccagaagctccgggagaagcagcagctagaagaggatcttaagggctacttggattgg
attacccaagcagaagacatcgatcctgagaatgaggaagaaggaggagaggaaggcaaa
cgaaatactagcatgcccaccagtgagaccgagtctgtgaacacggagaacgtaagcggc
gaaggcgagaaccaaggctgctgtgcaagtctctggtgctggtggaagagaagaggcgcg
gccaaggctgggccttcagggtgtcggcgctggagtgggctgctctcaggcttcagatcc
cgacgctggcgtcgctggaatcgattcagtcgaagaagatgtagggctgccgtgaagtct
gtcacgttttactggctggttattgtcctggtgtttctcaacaccttaaccatttcctct
gagcactacaaccagcctgactggttgacacagattcaagatatcgctaacaaagtcctc
ttggctctgttcacctgtgagatgttggtaaaaatgtacagcttgggactccaggcgtat
ttcgtctctcttttcaatcggtttgattgcttcgtggtgtgtggtggaattaccgaaact
attttagtggaactggaaatcatgtctcccctgggaatctccgtgtttcggtgtgtgcgc
cttttaagaattttcaaagtgaccaggcactggacttccctcagcaacctcgtggcgtcc
ttgttaaactccatgaagtccatcgcttcactgctgcttctgctctttctcttcatcatc
atcttttccttacttgggatgcagctgtttggcggcaagtttaattttgatgaaacgcaa
accaagcggagtacttttgacaatttccctcaagcgcttttaacagtgttccagatcctg
acaggtgaagactggaatnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn
nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnntc
cagggatggtcgttctgcatctacttcatcatccttttcattggcggtaactatattctg
ttgaatgtcttcttggccatcgccgtggacaatttggctgacgctgaaagtttgaacact
gctcagaaagaggaagcagaagaaaaagagcggaaaaagattgccagaaaagagagcctg
gaaaataaaaagaacaacaaaccagaagtcaaccagatagccaacagtgacaacaaggtt
acaattgatgactaccgagaagaggatgaggacaaggacccctacccaccttgtgatgtg
ccagtaggggaagaggaagaggaggaggaagaggatgaacccgaggtccctgctggtccc
cgtcctcgcagaatctcagagttaaacatgaaggagaaaatcattcccatccctgaagga
agcgctttcttcattcttagcaagaccaacccgatccgcgtgggctgccacaagctcatc
aaccaccacatcttcactaaccttatcctggtcttcatcatgctgagcagcgctgccctc
gcggccgaggaccccatccgcagccactccttccggaacactatactgggttactttgac
tatgctttcacagccatctttactgttgaaatcctgttgaagatgacgacttttggagct
ttcctccacaaaggggctttctgcaggaactacttcaatttgctggatatgctggttgtt
ggggtgtctctggtgtcatttgggattcaatccagcgctatctccgttgtgaagattctg
agggtcctaagggtcctcaggcccctcagggcaatcaacagagcaaaaggacttaagcat
gttgtccagtgtgtctttgtggccatccggacaatcggcaacatcatgatcgtcaccacc
cttctccagttcatgtttgcctgtattggggtccagttgttcaagggaaagttctatcgc
tgcacagatgaagccaaaagtaaccctgaagaatgcagggggcttttcattctctacaag
gatggggaggtcgataaccctgtggtgcgtgagaggatctggcagaacagtgatttcaat
tttgacaacgtcctatctgctatgatggcacttttcacagtctccacatttgagggctgg
cctgcattgctgtataaagctattgactcaaacggtgagaacgtcggcccgatctacaac
taccgcgtggagatctccatcttcttcatcatctacatcatcattgtggctttcttcatg
atgaacatctttgtgggtttcgtcatcgttacgtttcaggagcagggagaaaaagagtat
aagaactgtgagctggacaaaaatcagcgtcagtgcgttgaatatgccttgaaagctcgt
cctttgcggagatacatcccgaaaaacccctaccagtacaagttctggtacgtggtgaac
tcctcgcctttcgaatacatgatgtttgtcctcatcatgctcaacacactctgcttggcc
atgcagcactatgagcagtctaagatgtttaatgacgccatggacatcctgaacatggtc
ttcactggggtgttcaccgttgagatggttttaaaagtcattgcatttaaacctaagcac
tatttcactgatgcatggaacacttttgatgccttaattgttgttggtagcgtcgttgat
attgctataactgaagtgaatccaactgaaagtgaaaatgtccctgtcccaactgctgca
cctgggaactctgaagagagcaatagaatctccatcacctttttccgtcttttccgagtg
atgcgactggtgaagcttctcagcaggggagaaggcatccggacattgctgtggactttt
attaaatcctttcaggccctcccatatgtcgcccttctcatagccatgcttttcttcatc
tatgctgtcatcggaatgcagatgtttgggaaagttgccctgagagataacaaccagatc
aataggaataataacttccaaacctttccccaggcggtactgctgctcttcaggtgtgcc
actggggaggcctggcaggaaatcatgctggcctgcctccctgggaagctgtgtgaccca
gagtcagattacaaccccggggaggagtacacgtgcgggagcaattttgccatcgtttat
ttcatcagtttttacatgctctgtgcatttctgatcatcaatctgtttgtggccgtcatc
atggacaactttgattatctgacccgggactggtctattttgggacctcaccatttagat
gaattcaaacgaatatggtcagaatatgaccctgaagcaaagggaaggataaaacacctg
gacgtggtcactctgcttcgacgtatccagcaccctnnggggtttgggaaattatgccca
cacagagtagcatgcaagagattagttgctatgaacatgcctctcaacagtgatgggaca
gtcatgttcaatgcaaccctgtttgccttggttcgaactgctcttaaaatcaagactgaa
gttgtccctccagctggtgatgatgaggtaaccgtggggaagttctatgccactttcctg
atacaggactactttaggaaattcaagaaacggaaagaacaaggactggtgggaaaacac
ccagcgaagaacaccacaattgccctacaggcgggattaaggacactacacgacattggg
ccagaaatccggcgggctatatcctgtgatttgcaagatgatgagccagaagaagcaaac
cgagaagaagaagatttgttcaaaagaaatggtgccctgcttggaaaccatgtcaatcat
gttaatagtgataggagagattcccttcagcagaccaataccacccaccgtcccctgcat
gtccaaaggccttcaattccacctgcaagtgatactgagaaaccgctgtttcctccagca
ggaaattcggtgtgtcataaccatcataaccataattccataggaaagcaaattcccaac
tcaacaaatgccaatctcaataatgccaatatgtccaaagctgcccatggcaagcggccc
agcattgcgaaccttgagcatgtgtctgacaatgggcatcattcctcccacaagcatgac
cgtgagcctcaaagaaggtccagttttaaaagaacccgctattatgaaacttacgttagg
tccgactctggagatgaacagctcccgactatttgctgggaagattcagagatacatggc
tacttccaggatccccgctgcttaggggagcaggagtatttcagcagtgaggaatactac
gaggatgacagctcgccgaccagaagcaggcataacaatggctactacaacagataccca
ggcagcagcttggacttcgaaaggccccgaggctaccaccacccccaaggcttcttagag
gacgatgactcacccgtttgctacgatcggagatctccaaggagacgcctactacctcca
accccaacatcccaccggagatcctccttcaactttgagtgcctgcggaggcagggcagc
caggaagaggtcccgccgtcgccggcttttccccaccgcacagcgctgcctctgcacctc
atgcagcaacagatcatggcagttgcaggcctagattcgagcaaagtccagaagtactca
ccgagtcactcgacccggtcatgggccacccccccagcgacgcccccctaccaggactgg
acgccctgctacacccccctgatccaggtagagcggtcagagtccctggaccaggtcaat
ggcagcctgccgtccctgcaccgcagttcctggtacacagatgaacctggtatcgcctat
cggactttcacgccagccagcctgactgtccccagcagcttccggaacaaaaacagcgac
aagcagaggagtgcggacagcttggtggaggcagtcctcatatctgaaggcttaggacgg
tatgcaagggacccgaaatttgtatcagcaacaaaacatgagattgccgatgcctgtgac
ctaaccattgacgagatggagagtgcagccagccacctgctcaacgggaacgtgagtccc
cgagccaatggggacgtgggccccgtctcacaccagcaggactatgagctacaagacttt
ggttctggctacagcgatgaagagccagaccctgggagatatgaggaggacctggcagat
gaaatgatatgcatcactaccttgtag
DBGET
integrated database retrieval system
