Loxodonta africana (African savanna elephant): 100660030
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Entry
100660030 CDS
T04351
Gene name
PDPK1
Definition
(RefSeq) 3-phosphoinositide-dependent protein kinase 1 isoform X1
KO
K06276
3-phosphoinositide dependent protein kinase-1 [EC:
2.7.11.1
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav01524
Platinum drug resistance
lav03320
PPAR signaling pathway
lav04068
FoxO signaling pathway
lav04071
Sphingolipid signaling pathway
lav04140
Autophagy - animal
lav04150
mTOR signaling pathway
lav04151
PI3K-Akt signaling pathway
lav04152
AMPK signaling pathway
lav04210
Apoptosis
lav04510
Focal adhesion
lav04660
T cell receptor signaling pathway
lav04664
Fc epsilon RI signaling pathway
lav04722
Neurotrophin signaling pathway
lav04910
Insulin signaling pathway
lav04919
Thyroid hormone signaling pathway
lav04931
Insulin resistance
lav04960
Aldosterone-regulated sodium reabsorption
lav05145
Toxoplasmosis
lav05205
Proteoglycans in cancer
lav05213
Endometrial cancer
lav05215
Prostate cancer
lav05223
Non-small cell lung cancer
lav05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
100660030 (PDPK1)
04071 Sphingolipid signaling pathway
100660030 (PDPK1)
04151 PI3K-Akt signaling pathway
100660030 (PDPK1)
04152 AMPK signaling pathway
100660030 (PDPK1)
04150 mTOR signaling pathway
100660030 (PDPK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100660030 (PDPK1)
09143 Cell growth and death
04210 Apoptosis
100660030 (PDPK1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100660030 (PDPK1)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
100660030 (PDPK1)
04664 Fc epsilon RI signaling pathway
100660030 (PDPK1)
09152 Endocrine system
04910 Insulin signaling pathway
100660030 (PDPK1)
03320 PPAR signaling pathway
100660030 (PDPK1)
04919 Thyroid hormone signaling pathway
100660030 (PDPK1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
100660030 (PDPK1)
09156 Nervous system
04722 Neurotrophin signaling pathway
100660030 (PDPK1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100660030 (PDPK1)
05231 Choline metabolism in cancer
100660030 (PDPK1)
09162 Cancer: specific types
05215 Prostate cancer
100660030 (PDPK1)
05213 Endometrial cancer
100660030 (PDPK1)
05223 Non-small cell lung cancer
100660030 (PDPK1)
09167 Endocrine and metabolic disease
04931 Insulin resistance
100660030 (PDPK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100660030 (PDPK1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100660030 (PDPK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lav01001
]
100660030 (PDPK1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
lav04131
]
100660030 (PDPK1)
Enzymes [BR:
lav01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100660030 (PDPK1)
Protein kinases [BR:
lav01001
]
Serine/threonine kinases: AGC group
PDK1 family
100660030 (PDPK1)
Membrane trafficking [BR:
lav04131
]
Exocytosis
Calcium ion-dependent exocytosis
Acrosomal exocytosis proteins
100660030 (PDPK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PH_3
PK_Tyr_Ser-Thr
Kinase-like
Pkinase_fungal
APH
Kdo
Motif
Other DBs
NCBI-GeneID:
100660030
NCBI-ProteinID:
XP_010595691
UniProt:
G3SPQ1
LinkDB
All DBs
Position
Unknown
AA seq
558 aa
AA seq
DB search
MARTTSQLYDAVPIQPSVVLCSCSSPSMVRSQTDAGSAPAVPSSSSRQGPSMDGTMVEPR
PGANALQHAAQPPAQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHI
IKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFD
ETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQAR
ANSFVGTAQYVSPELLTEKAACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLE
YDFPEKFFPKARDLVEKLLVLDATKRLGCEEMDGYTPLKAHSFFESIIWENLHHQTPPKL
TAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSCHSLSAPEPGLPQRSGSNIEQYIHD
LDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLL
TEGPHLYYVDPINKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCKK
IQEVWRQRYQNQPDAAVQ
NT seq
1677 nt
NT seq
+upstream
nt +downstream
nt
atggcccggaccaccagccagctctatgacgccgtccccatccagcccagcgtggtgtta
tgttcctgctcatccccatccatggtgaggagccagactgatgccggcagcgcccctgct
gttcccagcagcagcagcaggcaggggcccagcatggatggcaccatggttgagcccagg
cctggcgccaatgccctgcagcacgctgctcagccgccggcccagcctcgcaagaagcgg
cccgaagacttcaagtttggaaagattcttggcgaaggctctttttccacagtcgtcctg
gcccgagaactggccacctcaagagaatatgcgattaaaattcttgagaaacgtcacatc
atcaaggagaacaaggtcccgtatgtgaccagagaacgggatgtgatgtcgcgcctggac
caccccttcttcgtgaagctttacttcacattccaggatgacgagaagctgtattttggc
cttagttatgccaaaaatggagaactacttaaatacattcgcaaaattggctcattcgat
gagacctgtacccgattttataccgccgaaatcgtgtctgctttagagtacctgcatggc
aaaggcatcatccacagggaccttaaaccagagaacattctgttgaatgaagacatgcat
atccaaatcacagactttggaaccgccaaagtgctctcccctgagagcaagcaagccagg
gccaactcatttgtgggaacagcccaatacgtctctccagagctgctcacagagaaggcg
gcctgtaaaagttcagacctttgggcccttggctgcataatctaccagcttgtggcagga
ctcccaccgttcagagcaggaaatgagtatcttatcttccagaagatcattaagttggaa
tatgactttccagaaaaattcttccccaaggccagagaccttgtggaaaagcttttggtc
ttagatgccacgaagcgattaggctgtgaggagatggacggttacacgcctctgaaagcc
cactcgttcttcgagtctatcatatgggagaacctgcaccaccagacacccccaaagctc
acggcctacctgccagcgatgtccgaggacgatgaggactgctacgggaactatgacaac
ctcctgagccagttcggctgcatgcaggtatcctcatcatcctcgtgccactccctatca
gccccagagccaggcctcccacagcgctctggcagcaacatcgagcagtacatccacgac
ctggattcgaactcttttgaactggacttacagttctctgaggatgagaagaggttactg
ttggagaagcaggctggtgggaacccttggcaccagtttgtagaaaataacttaatacta
aaaatgggtccagtagataagcggaagggtttatttgctcgccgacgacagctactgctc
acagaagggccacatctatactacgtggatcccatcaacaaagtcctgaaaggggagatc
ccatggtcacaggagctccgaccagaggcgaagaactttaaaaccttctttgttcacaca
cctaaccggacgtactacctgatggacccaagcggcaatgctcacaagtggtgcaagaag
atccaggaggtgtggaggcagaggtaccagaaccagccggacgctgctgtgcagtga
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