Loxodonta africana (African savanna elephant): 100662653
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Entry
100662653 CDS
T04351
Gene name
CFTR
Definition
(RefSeq) cystic fibrosis transmembrane conductance regulator
KO
K05031
cystic fibrosis transmembrane conductance regulator [EC:
5.6.1.6
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav02010
ABC transporters
lav04024
cAMP signaling pathway
lav04152
AMPK signaling pathway
lav04530
Tight junction
lav04971
Gastric acid secretion
lav04972
Pancreatic secretion
lav04976
Bile secretion
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
100662653 (CFTR)
09132 Signal transduction
04024 cAMP signaling pathway
100662653 (CFTR)
04152 AMPK signaling pathway
100662653 (CFTR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
100662653 (CFTR)
09150 Organismal Systems
09154 Digestive system
04971 Gastric acid secretion
100662653 (CFTR)
04972 Pancreatic secretion
100662653 (CFTR)
04976 Bile secretion
100662653 (CFTR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
lav02000
]
100662653 (CFTR)
Enzymes [BR:
lav01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.6 channel-conductance-controlling ATPase
100662653 (CFTR)
Transporters [BR:
lav02000
]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC7 subgroup
100662653 (CFTR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
CFTR_R
ABC_membrane
ABC_tran
SMC_N
AAA_21
AAA_29
RsgA_GTPase
AAA_16
T2SSE
DUF87
Zeta_toxin
MMR_HSR1
MeaB
NTPase_1
AAA_30
Intein_splicing
Motif
Other DBs
NCBI-GeneID:
100662653
NCBI-ProteinID:
XP_023400429
LinkDB
All DBs
Position
Unknown
AA seq
1637 aa
AA seq
DB search
MHLANLTRAWWLGSREKGGGRSGEVGGGGSRVGRNLARRTVQEASRGAGSPPAGGCSVLE
CRRLDLESGRDCCAPVGKAGLSGLGPARSAHEGGRPARRTGKGRRRAAREGRRRKGRSGR
VARGGCAGGGESSLNKFGAGPGSACLSTWAMEEGEGAKERGGVWSRGGSGELEANDITAG
QRKRGERPALRRVGRVWPLRATAQSSSSGTLAPRRTMQKSPLERASVISKLFFSWPGPIL
RKGYRQHLKLSDIYQIPSVDSADNLSEKLEREWDRELASKKNPKLINALRRCFFWRFVFY
GILLYLGEVTKAVQPLLLGRIIASYDPDNKVERSIAIYLAIGLCLLFIVRTLLLHPAIFG
LHHMGMQMRIAMFSLIYKKTLKLSSRVLDKISIGQLVSLLSNNLNKFDEGLALAHFVWIA
PLQVTLLMGLIWDLLQASAFCGLAFLIIVALGQAGLGRMMMKYRDKRAGKINERLVITSE
MIENIQSVKAYCWEEAMEKMIENLRQIELRLTRKAAYVRYFNSAAFFFSGFFVVFLSVLP
YAMLKGIILRKIFTTISFCIVLRMAVTRQFPWAVQTWYDSLGAINKIQDFLQKQEYKTLE
YNLTTTDVVMENVTAFWEEGFGELFEKAKQNNNNREISNGDNSLFFSNFSLLGAPVLKDI
NFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSWIMPGTIKE
NIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYK
DADLYLLDSPFGYLDVLTEKEIFESCVCKLMANKTRILVTSKMEHLKKADKILILHEGSS
YFYGTFSELQTLRPDFSSELMGYDSFDQFSAERRNSILTETLRRFSLEGDTVSWNETKKQ
SFKQAGEFGEKRKNSILNSINSIRKFSVVQKTPLQMNGIDEDSDEPLERRLSLVPDSEQG
EAILPRSNVINTGPTFQRRRRQSVLNLMTRPSINQGQNIHRRTAASARKMSLAPQANLTE
MDIYSRRLSQDSGLEISEEINEEDLKECFFDDVENMPPVTTWNTYLRYVTVHKSLIFVLI
WCLVVFLAEVAVSLVVLYLLRTSSLQDKGNNTTVNANSSYGVIVTNTSSYYLLYIYVGIA
DSLFALAIFRGLPLVHTLIKVSKTLHHKMLRSILQAPMSTFNTLKAGRILNRFSKDIAIL
DDLLPLTMFDFIQLLLIVIGAVVVVSVLQPYIFLATVPVIAAFIILRAYFLHTSQQLKQL
ESEARSPIFTHLVTSVKGLWTLRAFGRQPYFETLFHKALNLHTANWFLYLSTLRWFQMRI
EIIFVIFFIAVTFVSILTTGEGEGTIGIILTLAMNIMNTLQWAVNSSIDVDSLMRSVSRI
FKFIDMPTEESKPAKSVKPPKDGQLSKVMIIENQHVKKDYNWPSGGHMTVKDLTAKYIDG
GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNTEGEIQIDGVSWDSITLQQW
RKAFGVIPQKVFIFSGTFRKNLDPYEQCSDQEIWKVADEVGLRSVIEQFPGKLDFVLVDG
GYVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPITYQIIRRTLKQAFADCTVILCEH
RVEAMLECQQFLVSLYN
NT seq
4914 nt
NT seq
+upstream
nt +downstream
nt
atgcaccttgcaaacttaacacgagcgtggtggctaggatctcgggagaaaggaggagga
aggagcggggaagttggcggcggagggtccagggtcgggcggaacctggcgcgtaggacg
gtccaggaggcttcccgcggggccggttcccctcctgccggtggctgctctgtcctcgag
tgccggagactggacctggagagcggccgtgactgttgcgcacctgtgggtaaggctgga
ctgtcgggactaggacctgcgaggagcgcgcatgagggagggaggccggcacgtagaacc
gggaaagggaggcgcagggcagcgagggagggaaggaggcgaaaaggaaggagcggtcgg
gttgcgcgcggagggtgcgcaggaggtggagaaagcagcttgaacaaatttggagccgga
ccaggcagcgcttgtctttcaacttgggcaatggaggagggggaaggagcaaaggaaagg
ggaggtgtgtggagtaggggtgggtcgggggagttggaagcaaatgacatcacagcaggt
caaagaaaaaggggcgagcgcccggcactgcgaagagtagggcgagtttggccattaaga
gctacagcccagtcatcctcgtcagggaccctggcgccccgcaggaccatgcagaagtcg
cctttggaaagggccagcgtcatctccaaacttttcttcagctggcccggaccaattttg
aggaaaggttacagacagcacctgaaattatcagacatataccaaatcccatctgttgat
tctgctgacaatctctctgaaaaactggaaagagaatgggacagagagctggcttccaag
aaaaatcccaaactcattaatgcccttcggcgatgctttttctggagatttgtgttctat
ggaatcttgttatatttaggggaagtcaccaaggcagtccagccactcttactgggaaga
atcatagcttcctatgatccagataacaaggtggaacgctccattgcgatttacttggcc
ataggcctgtgccttctcttcatcgtgaggacgctcctcctacacccagccatttttggc
ctccatcacatgggaatgcagatgagaatagctatgtttagtttgatttataagaagact
ttaaaactgtccagccgtgttcttgataaaataagtattggacaacttgtcagtctcctt
tccaacaacctgaacaaatttgatgaaggacttgcactggcacattttgtgtggattgct
cctttacaagtgacacttctgatggggctgatctgggacctgctccaggcctctgccttc
tgtggacttgctttcctgataattgtcgcccttggtcaagctgggttaggaagaatgatg
atgaagtacagagataagagagctggaaagatcaatgaaagacttgtgatcacctctgaa
atgattgaaaatatccaatctgtgaaggcatactgctgggaggaagcaatggaaaaaatg
atcgaaaacctaagacaaatagagctgagactgacccggaaggcagcctatgtgagatac
ttcaacagcgcagccttcttcttctcagggttcttcgtggtgtttttatctgtgctgccc
tacgcaatgctcaaaggaatcatccttcgaaaaatattcactaccatctcattctgcatc
gttctgcgcatggctgtcactcggcagttcccctgggctgtgcaaacgtggtatgactcg
ctcggagcaataaacaaaatacaggatttcttacaaaagcaagagtataagacgttggaa
tataacttaacaactacagatgtggtgatggaaaatgtgacagccttctgggaggaggga
tttggggaattatttgagaaagcaaaacaaaataataacaatagagaaatttccaatggt
gataacagcctcttcttcagtaacttctcacttcttggtgctcctgtcctgaaggatatc
aatttcaagatagaaagaggacagttattggcggttgctggatctactggagcaggcaag
acttcacttctaatgatgattatgggagaactggagccctcagagggtaaaattaagcac
agtggaagaatttcattctgttctcagttctcctggatcatgcctggcaccattaaagaa
aacatcatctttggtgtttcctatgatgagtatagatataggagtgtcatcaaagcctgc
cagctagaagaggacatttccaagtttgcagagaaagacaatatagttcttggagagggt
ggaatcacactgagtggagggcaacgagccagaatctcgttagcaagggcagtgtacaaa
gatgctgatttgtacctattagactctccttttggatacctagatgttttaacagaaaaa
gaaatttttgaaagctgtgtctgtaaattgatggcgaacaaaactagaattttggtcact
tctaaaatggaacatttaaagaaagctgacaaaatattaattttacatgaaggtagcagc
tatttttatgggacattttctgaactacaaactctacggccagacttcagctcggagctc
atgggatatgattctttcgatcagtttagtgcagaaagaagaaattcaatcctaacggag
accttacggcgtttctcattagaaggagatactgtctcctggaatgaaacaaaaaagcag
tcttttaaacaagctggagagtttggtgaaaaaaggaagaactctattctcaattcaatc
aactccataagaaaattttcagtagtacaaaagactccactacaaatgaatggtattgat
gaagattctgacgagcctttggagagaaggctgtccctagttccggattctgagcaagga
gaggccatcctacctcgaagtaacgtgatcaacacgggtcccacatttcagagacgaaga
agacagtctgttctcaacctgatgacacgcccctcaattaaccaaggtcaaaacattcac
cgaaggacagcagcatccgcacgaaaaatgtcactggcccctcaggctaacttaactgaa
atggatatatattcaagaagattatctcaagacagtggcttggaaataagtgaagaaatt
aatgaagaagatttaaaggagtgcttttttgacgacgtggagaacatgccaccagtgacc
acatggaacacataccttcgatatgttactgtccacaagagcttaatttttgtgctaatt
tggtgtttagttgtttttctggctgaggtggctgtttctttggttgtgttgtatctactt
aggacatcatctcttcaagacaaagggaataatactactgtgaacgcaaatagcagctac
ggagtgatcgtcactaacaccagctcatattatcttttgtacatttatgtgggaatagct
gacagtttgtttgccctggcaatcttcagaggtttaccactggtgcataccctaatcaaa
gtgtcaaaaactttacaccacaaaatgttacgttctattcttcaagcacctatgtcaacg
ttcaacacattgaaagcaggtaggattcttaatagattctccaaagatatagcaattttg
gatgatcttctgcctcttaccatgtttgacttcatccagttgttattaattgtgattggc
gctgtagtagtcgtctctgttttacaaccctacatcttcctggcaacagtgcccgtgata
gctgcgtttattatactgagagcatacttcctccacacctcacagcagctcaaacaattg
gaatctgaagccaggagtcccattttcactcatcttgttacaagcgtaaaaggactatgg
acgctccgtgcctttggacgccagccttactttgaaactctgttccacaaagctctgaat
ttacacactgccaactggttcttgtacctgtcgacacttcgctggttccaaatgagaata
gaaattatttttgtcatcttcttcattgctgttaccttcgtttccattttaacaacaggt
gaaggagaaggaacaattggcattattctaacattagccatgaatatcatgaacacattg
cagtgggctgtaaactccagcatagatgtggacagtttgatgagatctgtgagccgaatc
tttaagtttatcgacatgccaacagaagaaagtaaacctgccaaatctgtcaaaccaccc
aaggatggccagctgtccaaagttatgattattgagaaccagcacgtgaagaaagattac
aactggccctcagggggtcacatgactgtcaaagacctcacagcaaaatatatagatggt
ggcaatgccatattagagaacatttccttctcaataagtcctggccagagggtgggcctg
ttgggaagaactggatcagggaaaagcactttgttatcagcttttttgaggctgctgaac
actgaaggagaaattcagattgatggtgtgtcctgggattcaataactttgcaacagtgg
aggaaagcctttggagtgatcccgcagaaagtgttcatcttttctggaacatttagaaaa
aacttggatccctatgaacagtgtagtgatcaagaaatatggaaagttgcagatgaggtt
ggactcagatctgtgatagagcagtttcccgggaagcttgattttgtccttgtagacggg
ggttacgtcctaagccatggccacaaacagctgatgtgcctggccagatctgttctcagt
aaggcgaagatcttgctgcttgatgaacccagtgctcatttggatccgataacataccaa
atcattcgaagaaccctaaaacaagcattcgctgattgcacagtaatcctctgtgagcac
agggtagaagcaatgttggaatgtcaacaatttttggtgagtctttataattga
DBGET
integrated database retrieval system
