Loxodonta africana (African savanna elephant): 100665091
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Entry
100665091 CDS
T04351
Gene name
APAF1
Definition
(RefSeq) apoptotic protease-activating factor 1 isoform X2
KO
K02084
apoptotic protease-activating factor
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav01524
Platinum drug resistance
lav04115
p53 signaling pathway
lav04210
Apoptosis
lav04215
Apoptosis - multiple species
lav05010
Alzheimer disease
lav05012
Parkinson disease
lav05014
Amyotrophic lateral sclerosis
lav05016
Huntington disease
lav05020
Prion disease
lav05022
Pathways of neurodegeneration - multiple diseases
lav05134
Legionellosis
lav05152
Tuberculosis
lav05160
Hepatitis C
lav05161
Hepatitis B
lav05162
Measles
lav05164
Influenza A
lav05168
Herpes simplex virus 1 infection
lav05169
Epstein-Barr virus infection
lav05200
Pathways in cancer
lav05222
Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
100665091 (APAF1)
04215 Apoptosis - multiple species
100665091 (APAF1)
04115 p53 signaling pathway
100665091 (APAF1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100665091 (APAF1)
09162 Cancer: specific types
05222 Small cell lung cancer
100665091 (APAF1)
09164 Neurodegenerative disease
05010 Alzheimer disease
100665091 (APAF1)
05012 Parkinson disease
100665091 (APAF1)
05014 Amyotrophic lateral sclerosis
100665091 (APAF1)
05016 Huntington disease
100665091 (APAF1)
05020 Prion disease
100665091 (APAF1)
05022 Pathways of neurodegeneration - multiple diseases
100665091 (APAF1)
09171 Infectious disease: bacterial
05134 Legionellosis
100665091 (APAF1)
05152 Tuberculosis
100665091 (APAF1)
09172 Infectious disease: viral
05161 Hepatitis B
100665091 (APAF1)
05160 Hepatitis C
100665091 (APAF1)
05164 Influenza A
100665091 (APAF1)
05162 Measles
100665091 (APAF1)
05168 Herpes simplex virus 1 infection
100665091 (APAF1)
05169 Epstein-Barr virus infection
100665091 (APAF1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100665091 (APAF1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
NB-ARC
WD40
APAF1_C
ANAPC4_WD40
CARD
Ge1_WD40
WD40_like
CARD_2
AAA_16
Nbas_N
Utp8
AAA_22
ATPase_2
NACHT
Motif
Other DBs
NCBI-GeneID:
100665091
NCBI-ProteinID:
XP_003405326
LinkDB
All DBs
Position
Unknown
AA seq
1245 aa
AA seq
DB search
MDAKARNCLLQHREALERDIKTAYIMDHMISDGVLTLLEEEKVKIEPTQQQRAAMLIKMI
LQKDNYSYISFYNALLHEGYRDLADRLRGGLPDVSSSNGKDSVGGITSYVRTVLCEGGVP
QRPVVFVTRKKLVNAIQQKLSKLNGEPGWVTIYGMAGCGKSVLAAEAIRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDGNFSQRPPLNIEEAKDRLRILMLRKHPRSLL
ILDDVWDPWVLKAFDNQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVN
MKKADLPEQAHSIIKECKGSPLVVSLIGALLRDFPNRWEYYLRQLQNKQFKRIRKSSFYD
YEALDEAMSISVEMLREDTKNYYTDLSILQKDVKVPTKVLCILWDLETEEAEDILQEFVN
KSLLFCDRNGKSFRYYLHDLQVDFLTEKNCSQLQDLHKKMITQFQRYHQLHPLSPDQEDC
MYWYNFLAYHMASANMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCTV
CENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGTLYLEWINK
KNMKNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEV
LCCAFSADDRFIATCSVDKQVKIWDSVTGELVRTYDEHSEQVNCCHFTNNGHHLLLATGS
SDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDTLLASCSADGSLKLWDVRSANERKS
INVKQHFPDSEDPQEDIEVIVKCCSWSADGARIMVAAKNKIFLFDIDSSGLLAEIPTGHH
STIQYCDFSPHNHLAVVTLSQYCVELWNTDSCLKVADCRGHLSWVHSVMFSPDGSSFLTS
SDDQTIRVWETKKVCKNSAVVLKQEVDVVFQENEVMVLAVDNIKRLQLINGKTGQIDYLT
EAQVSCCCLSPQLQYVAFGDEDGAIEILELLNGRIFQSRIRHKKAVRHIQFTADGKTLIS
SSDDSTIQVWNWRSEEYVFLQAHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGRIEKD
FVCHQDTVLSCDISPDATKFSSTSADKTAKIWNFDLLFPLHELSGHTGCVRCSVFSVDST
LLATGDDNGEIRIWNVSNGELLGLCSVEGAATHGGWVTDLCFSPDSKMLVSSGAYLKWWN
VVTGESSQTFYTNGTNLKKIHVSPDFKTFVTVDNLGILYILQILE
NT seq
3738 nt
NT seq
+upstream
nt +downstream
nt
atggatgcaaaagctcgaaattgtttacttcaacacagagaagccctggaaagagacatc
aagacagcctatatcatggatcacatgattagtgatggagttttaacattattggaagag
gaaaaagtgaaaattgagcccactcaacagcagcgagcagctatgctaattaaaatgata
cttcaaaaagataattattcctacatatcattctacaatgctctactgcatgaagggtat
agagatctggctgaccgtctccgtggtggtcttcctgatgtctcttcttccaatggcaaa
gattcagttggtggaataacttcatatgtaaggacagtcctttgtgaaggtggagtacca
cagaggccagttgtttttgttactagaaagaagctggttaatgcaattcagcagaagctc
tccaaactgaacggtgaaccgggatgggtcaccatatatggaatggcaggctgcgggaag
tctgtattagctgcagaagctattcgagatcattccctcttagaaggttgtttcccaggg
ggtgtgcattgggtttcagttggaaaacaagataaatctgggcttctgatgaaactgcaa
aatctttgcacacgattggaccaagatggcaatttctcccagaggcctccacttaatatt
gaagaagctaaagaccgtctccgcatcctgatgctgcgcaaacacccgaggtcactcttg
atcttggatgatgtttgggatccttgggttttaaaagcttttgacaatcagtgtcaaatt
cttcttacaaccagagacaagagtgttacagattcagtaatgggccctaaatatgtggtt
cctgtggagagtagcttaggaaaagaaaaaggacttgaaattttatcgctttttgttaat
atgaagaaagcagatttgccagaacaagctcatagtattataaaagaatgtaaaggttct
cctcttgtagtgtctttaattggtgcacttttacgtgattttcccaatcgttgggagtac
tacctcaggcaacttcagaataagcaatttaagagaatcaggaaatcttcattttatgat
tatgaggctctggatgaagccatgtctataagtgttgaaatgctcagagaagacaccaag
aattattacacagatctttccatcctccagaaggatgttaaagtgcctacaaaggtgtta
tgtattctctgggacttggaaactgaagaggctgaagacatactgcaggagtttgttaat
aagtccctcttattctgcgatcgaaatggaaaatcatttcgttattatttacatgatctt
caagtagatttccttacagagaagaattgcagccaacttcaggatctgcataagaagatg
attactcagttccaaaggtatcaccagctacatcctctttcaccagatcaggaggattgc
atgtactggtacaactttctggcctatcacatggccagtgccaatatgcacaaagaactt
tgtgctttaatgttttccctggattggattaaagcaaaaactgaacttgtaggccctgct
catctgattcatgaatttgtggaatataggcatatattggatgagaaggattgcacagtc
tgtgagaattttcaggaatttttatctttaaatggacaccttcttggacgacagccattt
cctaatattgtacaactgggtctctgtgaaccggaaacttcagaagtttatcagcaagct
aagcttcaggccaagcaggaggtcgataacggaacgctttacctggagtggataaacaaa
aaaaacatgaagaatctctcccgcttagttgtccgcccccatacggatgctgtttaccat
gcctgcttttctgaggatggtcagagaatagcatcttgtggagctgataaaaccttacag
gtgttcaaagctgagacaggagagaagcttctagaaatcaaggctcatgaagatgaagtg
ctttgctgtgcattctctgcagatgacaggtttatagcaacctgctcagtggataaacaa
gtgaaaatttgggattctgtgactggggaactagtacgtacctatgatgagcactcagag
caagtcaattgctgccatttcaccaacaacggtcatcaccttctcctcgccactggctca
agtgattgcttcctcaaactctgggatttgaatcaaaaagaatgtcgaaataccatgttt
ggccatacaaattcagtcaatcactgtagattttcaccagatgatacgcttttggccagt
tgttcagctgatggatcattaaagctttgggatgtgagatcagcaaatgagaggaaaagc
attaacgtgaaacagcacttcccagattcagaggatcctcaagaggatatagaagtgata
gtgaaatgttgttcctggtctgctgatggtgccaggataatggtggcagcaaaaaataaa
atctttctttttgacattgattccagtggcctattggcagaaatccccacaggacatcat
agtaccatccagtactgtgacttctctcctcataaccatttggcagtggtgactttgtcc
cagtactgtgtggagttgtggaatacagactcgtgtttaaaagtagctgactgcagagga
catttaagttgggttcattctgtgatgttttctcctgatggttcatcatttttgacatct
tctgatgaccagacaatcagggtctgggagacaaagaaagtatgtaagaactctgcagta
gtgttaaagcaagaagtagatgttgtgtttcaagagaatgaagtgatggttcttgcagtt
gacaatataaaacgtctacaactcattaatggaaaaacaggtcagattgattacctgact
gaagctcaagttagctgctgttgcttaagtccacaacttcagtacgttgcatttggagat
gaagatggggccattgagattttagaactcctaaatggcagaatcttccagtccaggatt
agacacaagaaagctgtacggcacattcagttcacagctgatgggaagactcttatttca
agctccgatgattctacaattcaggtatggaattggcggtcagaggaatatgtctttctg
caagcccatcaggaaacagtgaaagacttcaggctcttgaaaaattcaagactgctttct
tggtcatttgatggaacagtgaaggtgtggaatattattactggaagaatagaaaaagac
tttgtctgtcaccaggatacagtactctcttgtgatatttctcctgatgctaccaagttt
tcatctacctctgctgacaagactgcaaagatctggaattttgacctccttttccctctt
catgaattgagtggccacacaggctgtgtgcgctgctccgtcttctctgtggacagtacc
ctgctggcgactggagatgacaacggagaaatcaggatatggaatgtctcaaacggtgag
cttcttggtttgtgttcggtagaaggagctgctacccacggaggctgggtgaccgacctt
tgcttttctccagatagcaaaatgcttgtctcctctggggcatatcttaagtggtggaat
gttgtcactggggaatcttcacagaccttctacacaaatggaaccaatctgaagaaaata
cacgtgtcccctgacttcaaaacgtttgtgactgttgataatcttggtattttatatatt
ttacagattttagagtaa
DBGET
integrated database retrieval system
