KEGG   Loxodonta africana (African savanna elephant): 100667170
Entry
100667170         CDS       T04351                                 

Gene name
MAP3K7
Definition
(RefSeq) mitogen-activated protein kinase kinase kinase 7 isoform X2
  KO
K04427  mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav04010  MAPK signaling pathway
lav04064  NF-kappa B signaling pathway
lav04140  Autophagy - animal
lav04152  AMPK signaling pathway
lav04310  Wnt signaling pathway
lav04380  Osteoclast differentiation
lav04520  Adherens junction
lav04613  Neutrophil extracellular trap formation
lav04620  Toll-like receptor signaling pathway
lav04621  NOD-like receptor signaling pathway
lav04622  RIG-I-like receptor signaling pathway
lav04657  IL-17 signaling pathway
lav04660  T cell receptor signaling pathway
lav04668  TNF signaling pathway
lav05132  Salmonella infection
lav05135  Yersinia infection
lav05140  Leishmaniasis
lav05145  Toxoplasmosis
lav05161  Hepatitis B
lav05162  Measles
lav05168  Herpes simplex virus 1 infection
lav05169  Epstein-Barr virus infection
lav05170  Human immunodeficiency virus 1 infection
lav05171  Coronavirus disease - COVID-19
lav05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:lav00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100667170 (MAP3K7)
   04310 Wnt signaling pathway
    100667170 (MAP3K7)
   04064 NF-kappa B signaling pathway
    100667170 (MAP3K7)
   04668 TNF signaling pathway
    100667170 (MAP3K7)
   04152 AMPK signaling pathway
    100667170 (MAP3K7)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100667170 (MAP3K7)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    100667170 (MAP3K7)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    100667170 (MAP3K7)
   04620 Toll-like receptor signaling pathway
    100667170 (MAP3K7)
   04621 NOD-like receptor signaling pathway
    100667170 (MAP3K7)
   04622 RIG-I-like receptor signaling pathway
    100667170 (MAP3K7)
   04660 T cell receptor signaling pathway
    100667170 (MAP3K7)
   04657 IL-17 signaling pathway
    100667170 (MAP3K7)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100667170 (MAP3K7)
 09160 Human Diseases
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    100667170 (MAP3K7)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100667170 (MAP3K7)
   05135 Yersinia infection
    100667170 (MAP3K7)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100667170 (MAP3K7)
   05161 Hepatitis B
    100667170 (MAP3K7)
   05171 Coronavirus disease - COVID-19
    100667170 (MAP3K7)
   05162 Measles
    100667170 (MAP3K7)
   05168 Herpes simplex virus 1 infection
    100667170 (MAP3K7)
   05169 Epstein-Barr virus infection
    100667170 (MAP3K7)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100667170 (MAP3K7)
   05140 Leishmaniasis
    100667170 (MAP3K7)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lav01001]
    100667170 (MAP3K7)
Enzymes [BR:lav01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     100667170 (MAP3K7)
Protein kinases [BR:lav01001]
 Serine/threonine kinases: TKL group
  MLK family
   100667170 (MAP3K7)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase APH
Other DBs
NCBI-GeneID: 100667170
NCBI-ProteinID: XP_003404387
LinkDB
Position
Unknown
AA seq 606 aa
MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDV
AIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAE
PLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC
DIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIM
WAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQY
PCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQ
SESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAASTAYSKPKRGHRKTASFGN
ILDVPEIVISGNRPPRRRPPQDLTVTGTEPGQVNSRSSSPSVRMITTSGPTSEKPARSHP
WTPDDSTDTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEI
ALLLQRKQELVAELDQDEKDQQNTSRLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQ
KRQGTS
NT seq 1821 nt   +upstreamnt  +downstreamnt
atgtctacagcctctgccgcctcctcctcctcctcgtcttcggccggtgagatgatcgaa
gccccctcccaggtcctcaattttgaagagatcgactacaaggagatcgaggtggaagag
gttgttggaagaggagcctttggagtagtctgcaaagctaaatggagagcaaaagatgtt
gctattaaacaaattgaaagtgagtctgagaggaaagcttttattgtagagcttcgccag
ttatcccgggtgaaccatcctaatattgtaaagctatatggagcttgcttgaatccggtg
tgtcttgtgatggaatatgctgaagggggctctttatataatgtgctgcatggtgctgaa
ccattgccatattacactgctgcccatgcaatgagttggtgtttacagtgttcccaagga
gtggcttatcttcacagcatgcaacccaaagctctaattcacagggacctgaaaccacca
aacttattgctggttgcaggggggacagttctaaaaatctgtgattttggtacagcctgt
gacattcagacacatatgaccaataacaaggggagtgctgcatggatggcacctgaagtt
tttgaaggtagcaattacagtgaaaaatgtgacgtcttcagctggggtattatcctttgg
gaagtaataacacgtcggaaaccttttgatgaaattggtggccccgctttccgtatcatg
tgggctgttcacaacggtactagaccaccactgatcaaaaatttacctaagcccattgag
agcctgatgactcgttgttggtctaaagatccttctcaacgcccatctatggaggaaatt
gtgaaaataatgactcacttgatgcggtactttccaggagcagatgagcctttacagtat
ccttgtcagtattcagatgaaggacagagcaactctgccaccagtacaggctcattcatg
gacatcgcttctacaaataccagtaataaaagtgacactaatatggagcaagttcctgcc
acaaatgatactattaagcgcttagaatcaaaattgttgaaaaatcaggcgaagcagcag
agtgaatctggacgtttaagcctgggagcttcccgtgggagcagtgtggagagcctaccc
ccaacctccgagggcaagaggatgagtgctgacatgtctgaaatagaagcaaggatagct
gcatccacagcatattccaagcctaaacgaggccaccgtaaaactgcttcatttggcaac
attctggatgtccctgagatcgtcatatcaggtaaccggcccccaaggcgtagacccccc
caagacttgactgttactgggacagaacctggtcaggtgaacagtaggtcatccagtcct
agcgtcagaatgatcactacctcaggaccaacctcagaaaaaccagctcgaagtcatcca
tggacacctgacgattccacagatacgaatgggtcagataactccataccaatggcttat
cttacactggatcaccaactacagcctctagcaccatgcccaaactccaaagaatctatg
gcagtgtttgaacagcattgtaaaatggcacaagaatatatgaaagttcaaacagaaatt
gcattgttattacagagaaagcaggaactagttgcagaactggaccaggatgaaaaggac
cagcaaaatacatctcgtctggtacaggaacataaaaagcttttagatgaaaacaaaagt
ctttctacttactaccagcaatgcaaaaaacaactagaagtcatcagaagtcagcagcaa
aaacgacaaggcacttcatga

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