KEGG   Loxodonta africana (African savanna elephant): 100667431
Entry
100667431         CDS       T04351                                 

Gene name
THBS1
Definition
(RefSeq) thrombospondin-1
  KO
K16857  thrombospondin 1
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav04015  Rap1 signaling pathway
lav04115  p53 signaling pathway
lav04145  Phagosome
lav04151  PI3K-Akt signaling pathway
lav04350  TGF-beta signaling pathway
lav04510  Focal adhesion
lav04512  ECM-receptor interaction
lav05144  Malaria
lav05165  Human papillomavirus infection
lav05205  Proteoglycans in cancer
lav05206  MicroRNAs in cancer
lav05219  Bladder cancer
Brite
KEGG Orthology (KO) [BR:lav00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100667431 (THBS1)
   04350 TGF-beta signaling pathway
    100667431 (THBS1)
   04151 PI3K-Akt signaling pathway
    100667431 (THBS1)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    100667431 (THBS1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    100667431 (THBS1)
  09143 Cell growth and death
   04115 p53 signaling pathway
    100667431 (THBS1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100667431 (THBS1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    100667431 (THBS1)
   05205 Proteoglycans in cancer
    100667431 (THBS1)
  09162 Cancer: specific types
   05219 Bladder cancer
    100667431 (THBS1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    100667431 (THBS1)
  09174 Infectious disease: parasitic
   05144 Malaria
    100667431 (THBS1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:lav04131]
    100667431 (THBS1)
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins [BR:lav00536]
    100667431 (THBS1)
   04990 Domain-containing proteins not elsewhere classified [BR:lav04990]
    100667431 (THBS1)
Membrane trafficking [BR:lav04131]
 Endocytosis
  Phagocytosis
   Opsonins
    100667431 (THBS1)
Glycosaminoglycan binding proteins [BR:lav00536]
 Heparan sulfate / Heparin
  Extracellular matrix molecules
   100667431 (THBS1)
Domain-containing proteins not elsewhere classified [BR:lav04990]
 Thrombospondin domain-containing proteins
  Thrombospondins
   100667431 (THBS1)
SSDB
Motif
Pfam: TSP_C TSP_3 TSP_1 TSP1_spondin VWC cEGF EGF_3 TSP1_ADAMTS EGF_CA Laminin_G_3 TSP1_CCN Laminin_G_2 EGF Laminin_G_1
Other DBs
NCBI-GeneID: 100667431
NCBI-ProteinID: XP_010596632
LinkDB
Position
Unknown
AA seq 1169 aa
MGLAWGLGVLLLLQVCGTNRIPESGGDNSVFDIFELTGGSRKGSGRRLVRGPDPSSSAFR
IEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLALERKDHSGQVFSVV
SNGKAGTLDLSLTVQGKQHVVSVEDVLLATGQWKSITLFVQEDRAQLYIDCEKMENAELE
VPIQSIFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTNVLL
ALDNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSNMVLELRGLRTIVTTLQDSIRKV
TEENKELANELRRSPLCYHNGVQYRNNEEWTVDSCTECRCQNSVTICKKVSCPIMPCSNA
TVPDGECCPRCWPSDSADDGWSPWSEWTSCSVTCGNGIQQRGRSCDSLNNRCEGSSVQTR
TCHIQECDKRFKQDGSWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQLNGKPCEGEARET
KACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCIGDVTENQIC
NKQDCPIDGCLSNPCFAGAKCTSYPDGSWKCGACPAGYSGNGVQCTDVDECKEVPDACFN
HNGEHRCKNTDPGYNCLPCPPRFTGTQPFGQGIEHATANKQVCKPRNPCTDGTHDCNKNA
KCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNEDLVCVANATYHCKKDNCPNL
PNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYNH
NPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEHN
PDQLDSDSDRIGDTCDSNQDIDEDGHQNNLDNCPYVPNANQADHDKDGVGDACDHDDDND
GIPDDRDNCRLVSNPDQKDSDGDGRGDACKDDFDQDSVPDIDDICPENVDISETDFRRFQ
MIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAIGYDEFNAVDFSGTFFINTERDDD
YAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNALW
HTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYDK
TYAGGRLGLFVFSQEMVFFSDLKYECRDS
NT seq 3510 nt   +upstreamnt  +downstreamnt
atggggctggcctggggacttggtgtcctgctcctcctgcaagtgtgtggcaccaaccgc
attccagagtctgggggagataacagcgtgtttgacatctttgaactcaccggaggttcc
cgcaagggctctgggcgccggctggtgaggggccctgacccctccagctcagctttccgc
attgaggatgccaatctgatcccccctgtgcccgatgacaagttccaggacctagtagat
gctgtgcgggcagagaaggggttcctcctcctggcctctctgcggcagatgaagaagacg
cggggcacgctgctggccctcgagcggaaagaccactctggccaggtcttcagcgtggtc
tccaatggcaaggcgggcaccctggacctgagcctgactgtgcaggggaagcagcatgtg
gtgtcagtggaagacgtgctcctggcaaccggccaatggaagagcatcaccctgttcgtg
caggaggacagggcccagctgtacatcgactgtgagaagatggagaacgctgagctagag
gtccccatccaaagcatcttcaccagggacctggccagcatcgccaggctccgcattgca
aagggaggcgtcaatgacaatttccagggggtgctgcagaatgtcaggtttgtctttgga
accacaccagaagacatcctcaggaacaaaggctgctccagctctaccaacgtccttctt
gctctcgacaatgtggtgaatggttccagccctgccatccgcaccaactacatcggccac
aaaacaaaggacctgcaggccatctgcggcatctcctgtgatgagctgtccaacatggtc
ctggaactcaggggcctgcgcaccatcgtcaccacgcttcaggacagcatccgcaaagtg
actgaagagaacaaggaattggccaacgagctgaggcggtctcctctctgctatcacaac
ggagttcagtacaggaataacgaagagtggactgtggacagctgcaccgaatgtcgctgt
cagaactcagtcaccatctgcaaaaaggtatcctgccccatcatgccctgttctaacgcc
acagttcctgacggagaatgctgcccacggtgttggcccagcgactctgcagatgatggc
tggtctccatggtctgagtggacctcctgctccgtgacctgtggcaatggaattcagcag
cgcggccgctcctgcgatagcctcaacaaccgatgcgagggctcctcagtccagacacgg
acctgccacattcaggagtgcgataaaagatttaaacaggatggcagctggagccactgg
tccccgtggtcatcttgctcggtgacatgtggtgatggtgtgatcacaaggatccggctc
tgcaactctcccagcccccagttgaacgggaagccatgtgaaggggaagctcgagagact
aaagcctgcaagaaagacgcctgcccaatcaatggaggctggggtccctggtcaccatgg
gacatctgttctgtcacctgtggaggaggggtgcagaaacgtagccggctctgcaacaac
cccacaccccaatttggaggcaaggactgcattggtgatgtgacggaaaaccagatctgc
aacaagcaggattgtccaattgatggatgtctgtccaatccctgctttgccggtgccaag
tgtactagctaccccgatggcagctggaaatgtggtgcttgccctgcgggttatagcgga
aatggcgtccagtgcacagatgttgatgagtgcaaagaagtgcccgatgcctgcttcaac
cacaatggagaacacaggtgtaagaacacagaccccggctacaactgtctgccctgccca
cctcgcttcactggcacgcagccctttggccagggcatcgaacacgccaccgccaacaaa
caggtgtgcaagccccgcaacccctgcacagacgggacacacgattgcaacaagaatgcc
aagtgcaactacctcggccattacagcgaccccatgtaccgctgcgagtgcaagcctggc
tatgcaggcaacggcatcatctgcggagaggacacagacctcgacggctggcccaatgag
gacctggtctgtgtggccaatgcaacttaccactgcaaaaaggacaactgtcccaacctt
cccaactcagggcaggaagactatgacaaggatggaatcggcgatgcctgtgacgatgac
gatgacaatgataaaattccagacgatcgggacaactgtccattccattacaacccagcc
cagtatgactatgacagagatgatgtgggcgaccgctgtgataactgtccctacaaccac
aacccagatcaggctgacacagacaacaatggggaaggagacgcctgtgcggctgacatt
gatggggatggtatcctcaatgaaagagacaactgccagtacgtgtacaatgtcgaccag
cgggatacggatatggatggggttggagatcagtgtgataactgccccctggaacacaat
ccagatcagctggactctgactcggaccgcattggagatacctgtgacagcaatcaggat
attgatgaagatggccaccagaacaacctagacaactgcccctatgtgcccaacgccaac
caggccgaccacgacaaggatggcgtgggagatgcctgtgaccatgatgatgacaatgat
ggcattcctgatgacagggacaactgcagactggtgtccaatcctgaccagaaggactct
gacggtgatggtcgaggtgatgcttgcaaggatgattttgaccaggacagtgtgccagac
atcgatgacatctgtcctgagaatgttgacatcagtgagactgatttccgccgattccag
atgattcctttagatcccaaaggaacatcccaaaatgatcctaactgggttgtacgccat
cagggtaaagagcttgtccagactgtcaactgtgaccctgggcttgctataggttatgat
gaatttaatgctgtggacttcagtggcacattcttcatcaacaccgagagggatgatgac
tatgccggatttgtgtttggctaccagtccagcagccgcttctatgttgtgatgtggaag
caggtcacccagtcctactgggacaccaaccccacaagggctcaggggtactcaggcctt
tctgtgaaagttgtgaactccaccacaggacctggcgagcacctgcggaatgctctgtgg
catacaggaaacacccctggccaggtgcgaaccctgtggcatgaccctcgtcatataggc
tggaaagatttcactgcctacagatggcgtctcagccaccggccaaagacaggcttcatt
agagtggtgatgtatgaagggaagaagatcatggctgactcgggacctatctatgacaag
acctacgctggtggcaggctagggttgtttgtcttctctcaagaaatggtgttcttctcc
gacctgaaatacgagtgcagagattcctaa

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