Loxodonta africana (African savanna elephant): 100669213
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Entry
100669213 CDS
T04351
Gene name
GAB1
Definition
(RefSeq) GRB2-associated-binding protein 1 isoform X2
KO
K09593
GRB2-associated-binding protein 1
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav01521
EGFR tyrosine kinase inhibitor resistance
lav04012
ErbB signaling pathway
lav04014
Ras signaling pathway
lav04072
Phospholipase D signaling pathway
lav04722
Neurotrophin signaling pathway
lav05100
Bacterial invasion of epithelial cells
lav05205
Proteoglycans in cancer
lav05211
Renal cell carcinoma
lav05225
Hepatocellular carcinoma
lav05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100669213 (GAB1)
04014 Ras signaling pathway
100669213 (GAB1)
04072 Phospholipase D signaling pathway
100669213 (GAB1)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
100669213 (GAB1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100669213 (GAB1)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100669213 (GAB1)
05226 Gastric cancer
100669213 (GAB1)
05211 Renal cell carcinoma
100669213 (GAB1)
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
100669213 (GAB1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100669213 (GAB1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04990 Domain-containing proteins not elsewhere classified [BR:
lav04990
]
100669213 (GAB1)
Domain-containing proteins not elsewhere classified [BR:
lav04990
]
Pleckstrin homology (PH) domain-containing proteins
Grb-2 associated binder (Gab) family proteins
100669213 (GAB1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PH
PH_11
PH_9
PH_8
PH_3
PH_13
Motif
Other DBs
NCBI-GeneID:
100669213
NCBI-ProteinID:
XP_003417550
UniProt:
G3SQF6
LinkDB
All DBs
Position
Unknown
AA seq
694 aa
AA seq
DB search
MSGGEVVCSGWLRKSPPEKKLKRYAWKRRWFVLRSGRLTGDPDVLEYYKNDHAKKPIRII
DLNLCQQVDAGLTFNKKEFENSYIFDINTIDRIFYLVADSEEEMNKWVRCICDICGFNPT
EEDAVKPPGPSLQAPADLPLPVNTAPPSTHVDSSSATLPPPYQLINLPPHLETLGIQEDP
QDYLLLINCQSKKPEPMRTHADSAKSTSSETDCNDNVPSHKNPASSQSKHGVNGFFQQQM
MYDSPSSRAASVSVDSSLYNLPRSYSHDVLPKVSPSSTEADGELYVFNTPAGTSSVETQM
RHVSISYDIPSTPGNTYQIPRTFPEGTLGQTSKLETIPDIPPPRPPKPHPAHDRSPVETC
SITRTASDTDSSYCIPTAGMPPSRSNTISTVDLNKLRKDASSQDCYDIPRTFPSDRSSSL
EGFHNHFKIKNVLTVGSVSSEELNENYVPMNPNSPPRQHSTGFTEPIQEANYVPMTPGTF
DFSSFGMQVPPPAHMGFRSSPKTPPRRPVPVADCEPPPVDRNLKPDRKVKPAPLEIKPLT
EWEELQAPVRSPITRSFARDSSRFPLSPRPDSVHSTTSSSDSHDSEENYVPMNPNLSNED
PNLFGSNSLDGGSSPMVKPKGDKQVEYLDLDLDSGKSTPPRKQKSSGSGSSVADERVDYV
VVDQQKTLALKSTREAWTDGRQSTESETPTKSVK
NT seq
2085 nt
NT seq
+upstream
nt +downstream
nt
atgagcggtggcgaagtggtctgctcggggtggctccgcaagtccccgccggagaaaaag
ttgaagcgttatgcatggaagaggagatggtttgtgttgcgcagtggccgtttaactgga
gatccagatgtattggaatattacaaaaatgatcatgctaagaagcctatccgtatcatt
gatttaaatttatgtcagcaagtcgatgctggattgacatttaacaaaaaagagtttgaa
aacagctacatttttgatatcaacactattgaccggattttctacttggtagcagacagt
gaggaggagatgaataagtgggttcgttgtatttgtgacatctgtgggttcaaccctaca
gaggaagatgctgtgaagccacctggcccttccttacaagcaccagctgatttaccttta
cctgtaaatacagcaccaccgtccacacacgtggattcatcctctgctactctacctcct
ccatatcagctaattaaccttccaccacacctggaaactcttggcatccaggaggatcct
caagactacctcttgctaatcaactgtcaaagcaagaagcctgaacccatgagaacacat
gccgactctgcaaaatccacctcttcggaaacagactgcaacgataacgtcccttctcat
aaaaaccctgcttcttcccagagcaaacacggagtgaatggcttttttcagcagcaaatg
atgtatgactccccatcgtcacgtgctgcatctgtttctgtagactccagcctttataac
ctgcccaggagttactcccatgatgttttaccaaaggtgtctccatcaagtaccgaagca
gatggagaactctatgtttttaataccccagctgggacgtcgagtgtagagactcaaatg
cggcacgtatctatcagttacgacattccttcaacacctggtaacacttaccagattcca
cgaacatttccagaaggaaccttgggacagacgtccaagctagagactattccagatatt
cctccacctcggccaccgaaaccacatccagctcatgaccgatctcctgtggaaacgtgc
agtatcacacgcacggcctcagacactgacagtagttactgtatcccgacagcagggatg
cccccgtcacgtagcaataccatttccactgtggatttgaacaaattacgaaaagatgct
agctctcaagactgctatgatattccacgaacatttccaagtgatagatctagctcactt
gaaggcttccacaaccactttaaaatcaaaaatgtgttgacagtgggaagcgtatcaagt
gaagaactgaatgaaaattatgttcctatgaatcccaactctccaccacggcaacattcc
accggttttacggaaccaattcaggaagcaaattatgtgccaatgacaccagggacattt
gatttttcttcatttggaatgcaagttcctcctccggctcatatgggcttcaggtccagc
ccaaagacccctcccagaaggccagtgcctgtggcagactgtgaaccaccccccgtggat
agaaacctcaagccagacagaaaagtcaagccagcacctttggaaataaaacctttgaca
gaatgggaagaattacaagctccagttcgatctcccatcactaggagttttgctcgagac
tcctctaggtttcctctgtccccccgaccggattccgtgcatagcacaacttcaagcagt
gactctcacgacagcgaagagaattatgttcccatgaatccgaacctgtccaatgaagac
cctaatctttttggcagtaatagtcttgatggaggaagcagccctatggtaaagcccaaa
ggagacaaacaagtggaatacctagatttagatttagattctgggaaatccacaccacca
cgtaagcaaaagagcagcggctcaggcagcagtgtagcagatgagagggttgattatgtt
gtggttgaccaacagaagaccctggcactgaagagcacccgggaagcctggactgatggc
agacagtccacggaatctgaaacacccaccaagagcgtgaaatga
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