Loxodonta africana (African savanna elephant): 100670924
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Entry
100670924 CDS
T04351
Gene name
TSC2
Definition
(RefSeq) tuberin isoform X4
KO
K07207
tuberous sclerosis 2
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav04072
Phospholipase D signaling pathway
lav04115
p53 signaling pathway
lav04140
Autophagy - animal
lav04150
mTOR signaling pathway
lav04151
PI3K-Akt signaling pathway
lav04152
AMPK signaling pathway
lav04211
Longevity regulating pathway
lav04218
Cellular senescence
lav04714
Thermogenesis
lav04910
Insulin signaling pathway
lav04919
Thyroid hormone signaling pathway
lav05163
Human cytomegalovirus infection
lav05165
Human papillomavirus infection
lav05168
Herpes simplex virus 1 infection
lav05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04072 Phospholipase D signaling pathway
100670924 (TSC2)
04151 PI3K-Akt signaling pathway
100670924 (TSC2)
04152 AMPK signaling pathway
100670924 (TSC2)
04150 mTOR signaling pathway
100670924 (TSC2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100670924 (TSC2)
09143 Cell growth and death
04115 p53 signaling pathway
100670924 (TSC2)
04218 Cellular senescence
100670924 (TSC2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
100670924 (TSC2)
04919 Thyroid hormone signaling pathway
100670924 (TSC2)
09149 Aging
04211 Longevity regulating pathway
100670924 (TSC2)
09159 Environmental adaptation
04714 Thermogenesis
100670924 (TSC2)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
100670924 (TSC2)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
100670924 (TSC2)
05163 Human cytomegalovirus infection
100670924 (TSC2)
05165 Human papillomavirus infection
100670924 (TSC2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
lav01009
]
100670924 (TSC2)
Protein phosphatases and associated proteins [BR:
lav01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
100670924 (TSC2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Tuberin
DUF3384
Rap_GAP
Cnd1
HEAT
Motif
Other DBs
NCBI-GeneID:
100670924
NCBI-ProteinID:
XP_010595718
LinkDB
All DBs
Position
Unknown
AA seq
1745 aa
AA seq
DB search
MAKPTSKDSGLKEKFKILLGLGTPRPHPRSAEGRQTEFIITAEILRELSVECGLNNRIRV
IGQICEVAKTKKFEEHAVEALWKAVADLLQPDRPPEARHAVLALLKAIVQGQGDRLGVLR
ALFFKVIKDYPSNKDLHERLEVFKALTDNGRHITYLEEELAEFVLQWMDVGLSSEFLLVL
VNLVKFNSCYLDEYIASMVHMICLLCIRTSSSVDIEVSLQVLDAVVCYNCLPAASLPLFI
VTLCRTVNVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRAYMEDAPLLRGAVFFVG
MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRKELQAVTWDI
LLSIIERLLQQLLTLESQELRAIVHDLLTTVEELCDQNEFHGSQERYFELIERCADQRPE
SSLLNLISYRAQSIHPAKDDWIHNLQQLMERFFRNESRSAVRIKVLDILSFVLLINRQFY
EEELINSVVISQLSHIPEDRDPQVRKLATQLLVDLAEGCHTHHFNNLLDIIEKVIARSLF
PPPELEERDVPAYSASLEDVKTAVLGLLVILQTKLYTLPASHAARVYEMLVHHIQLHYKH
MYTLPIASSIRLQAFDFLLLLRADALHRLGLPNKDGAVRFSSYCLCDHMEPEHGLEKKAS
GPVSPPTGPTVPAPAGPTVRLGYLPYSLLFQVLLQCLKQETDWKVLKLVLSKLPESLRYK
VLIFTSPCSVDQLSSALCSMLSGPKTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYL
DKTKQREMVYCLEQGLIYRCASQCVVALAVCSVEMPDVIIKALPVLIVKLTHISATASMA
IPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC
RLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSRIQTSFTSASLGSA
DENSMAQADDNLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVG
NKLVTVTTSVGTGTRSLLGLDPGELQGGSELSSSPGVHVRQTKEAPAKLESQAGVQVCRR
ARDRVRSMSGGHGLRVGALDTLASYFPGGPICPGPQTMPVVKPQKASASTQMPVPKEKTN
LAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFK
EHRDTALYKSLSVPVASASKPSLLPRSNTDSPGVLEEGCAGEMNLSTELPELEDFKAASG
SDRRSQRTDAYSRSSSISSQEEKQLCAEELAARGIPIEQVVSSRGGQPCVDLSFQPSQPL
SKSSSSPELQTLQDIFGDAGDKADGGWLSPEAKARWQSGTLDGECAAWLAPGEEGRAHAP
AQHEGSLPCSSPRSPHGLRPRGYTISDPVQLRRGKTVERDTSNSRAAASNAEKVPGINPS
FVFLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELA
ILSNEHGSYRYTEFLTGLGKLIELKDCQPDKVYLGGLDVGGEDGQFTYCWHDDIMQAVFH
IATLMPTKDGDKHRCDKKRHLGNDFVSIVYNDSGEDFRLGTIKGQFNFVHVIITPLDYEC
NLVSLQCRKDMEGLVDTSMAKIVSDCNLPFVARQMALHANMASQVHHSRSNPTDIYPSKW
IARLRHIKRLRHRIREEANYLNPSLPLVQMHPPANTKAPAEATPTYETGQRKRLISSVDD
FTEFV
NT seq
5238 nt
NT seq
+upstream
nt +downstream
nt
atggccaagcccacaagcaaagattcaggcttgaaggagaagttcaagattctcctgggc
ctgggaacaccaaggccacatcccaggtctgcagagggcagacagacggagtttatcatc
acagcagaaatcctgagagaactgagtgtcgagtgtggtctgaacaatcgcatccgggtc
atagggcagatctgtgaagtagcaaaaactaagaagtttgaggagcatgccgtggaagca
ctgtggaaagctgtcgcggacttgctgcagccagaccggccaccagaggcacgacatgca
gtgctggccctgctcaaggccatcgtgcagggccagggtgaccgcctgggtgtgctccgt
gccctcttcttcaaggtcataaaggattacccttcgaacaaagacttgcacgaaaggctg
gaggtgttcaaggccctgacggacaatgggagacacataacctacttggaagaagagctg
gctgagtttgtcctgcagtggatggatgtgggcttatcctcagaattcctgctggtgctt
gtgaacctggtcaagttcaacagctgttaccttgatgaatacatcgcatccatggttcac
atgatctgtctgttgtgcatccggacctcgtcctccgtggacatagaggtgtccctgcag
gtgctggatgccgtggtctgctacaactgcctgcctgccgcgagcctgcccctattcatt
gtcacattgtgccgcaccgtcaacgtcaaggagctctgcgagccctgctggaagctgatg
cgtaacctcctgggaacccacctgggccacagtgccatctacaacatgtgccgcatcatg
gaggacagagcctatatggaggatgccccgctgctgagaggagctgtgttctttgtcggc
atggcgctgtggggggcccaccgactctactccctcaagaactcccctacatctgtgctg
ccgtcgttttatgaggccatgacctgccccaatgaggtggtgtcctacgaaatcgtcctc
tctatcaccagactcatcaagaagtacaggaaggagctgcaggctgtgacgtgggacatc
ctgctgagcatcatcgaacgtctgctccagcagctcctgaccctcgagagtcaggagctc
agagccatcgtgcatgacctgctgacgacggtggaggagctgtgtgaccagaatgagttc
cacggctcacaggagagatactttgagctcattgagcgatgcgccgaccagagacctgag
tcctccctcttgaacctgatatcctacagggcacagtccatccacccagccaaggatgac
tggatccacaacctgcagcagttaatggagaggttcttcaggaacgagtcccgcagtgct
gtgcgcatcaaggtgctggacatcctgtcctttgtgctgcttatcaaccggcagttctat
gaggaggagctgatcaactcagtggtcatctcccaactctcccacattccagaagacaga
gacccacaggtccgcaagctggccacccagttgctggtggacctggcggaaggctgccac
acccaccacttcaataatcttctggacatcattgagaaagtgattgctcgctccctgttc
cctcctcctgagctagaagaaagagatgtgcctgcgtactcggcctccttggaggatgtg
aagactgcggtcctggggctcctggtcatccttcagaccaagctctacactttgcctgcc
agccatgcagcacgggtatacgagatgcttgtccaccacatccagctgcactacaagcac
atgtacaccttgcccattgccagcagcatccggcttcaggcctttgacttcctgctgctg
ctccgggcagatgcactacaccgcctgggcctgcctaacaaggatggtgctgtacggttc
agctcctactgcctctgtgaccacatggagccagagcacggcttggagaagaaggccagt
ggccccgtctcgcctcccacggggcctaccgtcccagcacctgcaggccccactgtgcgg
cttggctatctgccctactccttgctcttccaagtcctgctgcagtgtctgaagcaggag
acggactggaaggtgctgaagctggtactcagcaagctgccggagtccctgcgctacaag
gtcctcatcttcacatccccctgcagcgtcgaccagctgtcctctgccctctgctccatg
ctttcaggtcccaagaccctggaacgactccgaggcacaccagagggcttctctagaacc
gacttacacttggcagtggttccagtgttgacagcactgatctcttaccataactacctg
gacaaaaccaaacagcgcgagatggtgtactgcttggagcaaggcctcatctaccgctgt
gccagccaatgtgtggtggccctggctgtgtgcagtgtggagatgcctgacgtcatcatc
aaggcactgcccgtactgattgtaaagctcacgcacatctcggccacagccagcatggcc
atcccgctgctcgagttcctgtcgactctggcccggctgccgcatctctacaggaacttt
gctgctgagcagtacgccagcgttttcgccatttcactgccctacaccaacccatccaaa
ttcaatcagtatattgtgtgcctggcccaccacgtgatagccatgtggttcattcggtgc
cgcctgcccttccggaaagattttgttccgtatatcactaagggccttcgctccaatgtc
ctcctgtcttttgatgacacccccgagaaggacagcttcagggcacggagcaccagtctc
aacgagaggcccaaaagtaggatccagacctccttcaccagtgccagcttgggttctgca
gacgaaaactcgatggcccaggcagacgacaacctgaaaaatctccacctggagctcacc
gagacgtgcctggacatgatggccagatacgtgttctccaacttcacagctgtccccaag
aggtctcccgtgggagaattcctcctggctggaggcaggaccaaaacctggctggtgggg
aacaagctggttaccgtaacgacgagtgtgggaactggcacacggtcgctgctgggccta
gacccaggcgagctgcagggtggctcagagcttagctccagccctggtgtacacgtgagg
cagacgaaagaggcgccagccaagctggagtcccaggctggggtacaggtgtgccgcagg
gcccgggaccgggtccgctccatgtcaggtggccatggcctgcgcgtgggagccctggac
actctagcctcctacttccctggaggccctatttgtccagggccgcagaccatgccggtc
gtgaagcctcagaaagcctcagcgagcacccagatgccagtgccaaaggaaaagacaaac
ctggctgcctacgtgcccctcctgacccagggctgggctgagatcctggtccggaggccc
acagggaacaccagttggttgatgagcctggagaatccactaagccctttctcttcggac
atcaacaatatgccactgcaggagttgtccaatgctctcatggccgctgagcgcttcaag
gagcaccgtgacacggccctgtacaagtcattgtcggtgccagtggccagcgcctccaag
ccctccctcctgccccgctccaacacagactccccgggggttctggaggaaggatgtgca
ggtgagatgaacttgtccactgagcttcctgagcttgaggacttcaaggcagcctcaggt
tcagacaggcgctcccagcgtaccgatgcttacagtaggtcatcttcgatctccagccaa
gaggagaagcagctgtgtgcagaggagctggctgccaggggaatccccattgagcaggtg
gtgtcctccaggggtggccagccctgtgtggacctctcctttcagccctcgcagcctcta
agcaaatccagctcctcacccgaactgcagaccttgcaggacatctttggggacgctggg
gacaaggccgatggaggctggctgagccctgaggccaaggcccggtggcagtcggggacc
ctggatggggagtgtgctgcctggctggctccaggtgaggagggccgggcccatgcccca
gcccagcacgagggctcactgccctgcagctccccacgctccccacacggcctgcggccc
cgaggctacaccatttccgacccagtccagttgcgcaggggcaagacagtggagagagac
acctccaacagccgagctgctgcctccaacgcggagaaggtgccaggcatcaaccccagc
tttgtgttcctgcagctctaccactcgcccttctttggggacgagtccaacaagccaatt
ctgttacccaacgagtccttcgagcgctcggtgcagctccttgaccagatcccttcgtat
gacacacacaagatcgctgttttgtacgtgggagagggccagagcaacagtgagctcgcc
atcctctccaacgagcacggctcctacaggtatacagaattcctgacgggcctgggcaag
ctcattgagctcaaggactgccagcctgacaaggtgtacctgggtggcttggatgtgggc
ggcgaggacggccagttcacctactgctggcatgatgacatcatgcaagcagtctttcac
atcgccaccctgatgcccaccaaggatggggacaagcaccgctgtgacaagaagcgccac
ctgggcaatgactttgtgtccattgtctacaacgactctggcgaggacttcaggctgggc
accatcaagggccagttcaacttcgtgcatgtgattatcactcctctggactatgagtgc
aacctggtctcactccagtgccggaaagacatggagggcctggtggacaccagtatggcc
aagatcgtgtctgactgtaacctgcccttcgtggcccgccagatggccttgcatgccaac
atggcctcccaggtccaccacagccgctctaaccccactgacatctacccttccaagtgg
attgcccggctccgccacatcaagcggctacgtcaccggatccgggaggaagccaattac
ctgaaccctagcctgcctctggtgcagatgcatcctccggccaacaccaaggcccctgca
gaggccacacccacctatgaaaccggccagagaaagcgcctcatctcctcagtagacgac
ttcacagaatttgtgtga
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integrated database retrieval system
