KEGG   Loxodonta africana (African savanna elephant): 100673374Help
Entry
100673374         CDS       T04351                                 

Gene name
SETDB1
Definition
(RefSeq) histone-lysine N-methyltransferase SETDB1 isoform X1
  KO
K11421  histone-lysine N-methyltransferase SETDB1 [EC:2.1.1.43]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav00310  Lysine degradation
lav04550  Signaling pathways regulating pluripotency of stem cells
Brite
KEGG Orthology (KO) [BR:lav00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    100673374 (SETDB1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100673374 (SETDB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:lav03036]
    100673374 (SETDB1)
Enzymes [BR:lav01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.43  histone-lysine N-methyltransferase
     100673374 (SETDB1)
Chromosome and associated proteins [BR:lav03036]
 Eukaryotic Type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     100673374 (SETDB1)
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    100673374 (SETDB1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: SET Pre-SET MBD DUF4537
Motif
Other DBs
NCBI-GeneID: 100673374
NCBI-ProteinID: XP_010587765
LinkDB All DBs
Position
Unknown
AA seq 1292 aa AA seqDB search
MSSIPECVGLEAATAAVESEEIAELQQAVVEELGISMEELRQFIDEELEKMDCVQQRKKQ
LAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRESSSEDEASRPT
EIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDL
HKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKS
LLSGNHIAYDYHPPPDKLYVGSRVVAKYKDGSQVWLYAGIVAETPNVKNKLRFLIFFDDG
YASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYITAYPNRPMVLLKSGQLIKTEWEG
TWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKQGGQLRTR
PNMGAVRSKGPVVQYTQDLTSTGTQFKPVEPPQPTALPALPVPPAPPLSPQATDIESLES
QLAQSRKQVAKKSTSFRPGSVGSGHSSPTSPTLGESTPGKPGLNQTYRSPLGSTTAAPTP
PTPPAPPAPPAFHGMLERAPIEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRSEQYRGKNP
LLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFC
LDPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFI
NTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVY
ECNKRCKCDANMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTD
DFADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCSSDSSGVDLKDQEDGNSGTDDPE
ESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETASKDSRPPDLGPPHTPV
PPSFPGAGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSRSSFKTTEGGEGRVWGIRG
EVERASTSGLGIKDEGDIKQPKKEDPDDRNKMAVVTESSRNYGYNPSPVKPEGLRRPPSK
TSMHQSRRLMASAQSSTDDVLTLSSSTESEGESGTSRKPAAGQTSATAVDSDDIQTISSG
SEGDDFEDKKNMSGPMKRQVAVKSTRGFALKSTHGIAIKSTNMASVEKGESAPVRKNTRQ
FYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGT
ELTWDYNYEVGSVEGKELLCCCGAIECRGRLL
NT seq 3879 nt NT seq  +upstreamnt  +downstreamnt
atgtcctccattcctgagtgcgtcggtttggaggcagcaactgctgcagtggagtctgaa
gagattgcagagctgcagcaggctgtggttgaggagctaggcatctctatggaggaactt
cggcagttcattgatgaagaactggaaaagatggactgcgtacagcagcgcaagaagcag
ctagcagaattggagacttgggtaatacagaaggaatctgaggtggcccatgttgatcag
ctctttgatgatgcatccagggcagtgactaattgtgagtctttggtgaaggacttctac
tccaagctgggactacaataccgggaaagtagctctgaggatgaagcttctcggcctaca
gaaataatcgagattcctgatgaagatgatgatgtactcagtattgattcaggtgatgct
gggagcagaactccaaaagaccagaagctccgtgaagctatggctgccttaagaaagtca
gctcaggacgttcagaagttcatggatgctgtcaacaagaagagcagttcccaggatcta
cataaaggaaccttaagtcaaatgtctggtgaactgagcaaagatggtgacctgatagtc
agcatgcggattctgggcaagaagagaactaagacatggcacaaaggcacgcttattgcc
atccagacagttgggccagggaagaagtacaaagttaagtttgacaacaaagggaagagt
ctgctgtcggggaaccacattgcctatgattatcaccctccccctgacaagctgtacgtg
ggcagtcgagtggtggccaaatacaaagatgggagtcaggtctggctctatgctggtatt
gtagctgagacaccaaacgtcaaaaacaagctcaggtttcttattttctttgatgacggc
tacgcttcctatgttacacagtctgaactgtatcctatttgccggccattgaaaaagact
tgggaggacatagaagacatctcctgccgagacttcatagaggaatatatcactgcctac
cccaaccgccccatggtgctactcaagagtggccagcttatcaagactgagtgggaaggc
acatggtggaagtcccgggtcgaggaggtggatggcagcctagtcaggatcctcttcctg
gatgacaaaagatgtgaatggatctatcggggctctacacggctggagcctatgttcagc
atgaagacatcctcggcctctgcgttggagaagaagcaagggggacagctcaggacacgt
ccaaacatgggtgctgtaaggagcaaaggccctgtggtccagtacacccaggatctaacc
agtactggaacccagttcaagccagtggagcccccacagcctacagctctgcccgcccta
cctgtcccgcctgccccacctctgtccccacaggcaactgacattgaaagcttggaaagc
cagcttgcccagtcacgaaagcaggtagccaaaaagagcacgtccttccggccaggatct
gtgggctctggtcattcctcccctacgtcccccactctcggtgaaagtacccctgggaaa
cctgggctcaatcagacatacagatcacctttaggctcaacaactgctgccccaacaccc
ccaacacccccagccccgccggcccctccagctttccatggcatgctggagagggccccg
atagagccctcctaccgcgcccccatggagaagctattctacttacctcatgtctgcagc
tatacttgtctgtctcgagtcagacctatgaggagtgagcagtaccggggcaagaacccc
ctgctagtcccactactgtatgacttccggcggatgacagcccggcgccgagtgaaccgc
aagatgggctttcatgttatctacaagacaccctgtggcctctgccttcggacaatgcaa
gagattgaacgctacctttttgagactggctgtgacttccttttcctggagatgttctgt
ttggatccctatgtccttgtggatcggaagtttcagccctataagcctttttactatatt
ttggacatcacttatgggaaggaagatgttcctctgtcctgtgtcaatgagatcgacaca
acccccccaccccaggtggcctacagcaaggaacgtatcccgggcaagggtgtgttcatt
aacacaggccctgaatttctggttggctgtgactgcaaggatgggtgccgggacaagtcc
aaatgtgcctgccatcagctaactatccaggctacggcctgcaccccagggggccaaatc
aaccctaactctggctaccagtacaagagactagaagagtgtctgcccacaggagtatat
gagtgtaacaagcgctgcaaatgtgatgccaacatgtgcacaaaccggctggtacagcac
gggctgcaggttcggctccagttattcaagacgcagaacaagggctggggtatccgctgc
ttggatgacattgccaagggctcctttgtctgtatttatgcaggcaaaattctaacagat
gactttgcagacaaggagggcctagaaatgggtgatgagtactttgcaaatctggaccat
atcgagagcgtggagaacttcaaagaaggatacgagagtgatgccccctgttcctctgat
agcagtggtgtagacttgaaggaccaggaagatggcaacagtggtactgatgaccctgaa
gagtccaatgacgatagttcagatgacaacttctgtaaggatgaggacttcagcaccagc
tctgtgtggcgcagctatgctacccggcggcagacccggggccaaaaggagaacggattg
tctgagacagcttccaaggactcccgccccccagatctcgggcccccacatactcctgtt
cctccgtctttccctggagctggctgcaatccaccttcctcagaagaaacacccaagaat
aaggtggcctcctggttgagttgcaatagtgtcagtgaaggtggctttgctgactctgat
agccggtcatccttcaagaccactgaaggcggggagggccgggtttggggaatccgaggg
gaggttgagagggcctccacttcaggactgggcatcaaggatgagggggacatcaagcag
cccaagaaagaggaccctgatgaccgaaacaagatggcagtagttactgaaagctctcga
aattatggttacaatccttctcctgtgaagcctgaaggactccgccgcccacctagtaag
actagtatgcatcagagccgacgactcatggcctctgctcagtccagcactgacgatgtc
ctgactctgtccagcagcacagaaagtgagggggaaagtggaaccagccgaaagccagct
gctggtcagacttcagccacagcagttgacagtgacgatatccagaccatctcctctggc
tctgaaggggatgattttgaggacaagaagaacatgtctggtccaatgaagcgccaagta
gcagtaaaatcaacccgaggctttgctcttaaatcaacccatgggattgccattaaatca
accaacatggcctctgtggaaaagggggagagcgcacctgttcgtaagaacacacgccag
ttctatgatggtgaggagtcttgctacatcatcgacgccaagcttgaaggcaacctgggc
cgctacctcaatcacagctgcagccccaacctgtttgtccagaatgtcttcgtggatacc
catgatcttcgcttcccctgggtggccttctttgccagcaagagaatccgggctgggaca
gaacttacttgggactacaactacgaggtgggcagtgtggaaggcaaggagctgctctgc
tgctgtggggccattgagtgcagggggcgtcttctttag

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