Loxodonta africana (African savanna elephant): 100676988
Help
Entry
100676988 CDS
T04351
Gene name
ABL2
Definition
(RefSeq) Abelson tyrosine-protein kinase 2 isoform X4
KO
K08887
abelson tyrosine-protein kinase 2 [EC:
2.7.10.2
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav04012
ErbB signaling pathway
lav04014
Ras signaling pathway
lav05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100676988 (ABL2)
04014 Ras signaling pathway
100676988 (ABL2)
09160 Human Diseases
09166 Cardiovascular disease
05416 Viral myocarditis
100676988 (ABL2)
Enzymes [BR:
lav01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100676988 (ABL2)
Protein kinases [BR:
lav01001
]
Non-receptor tyrosine kinases
ABL family
100676988 (ABL2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
F_actin_bind
SH2
SH3_1
SH3_2
SH3_9
SH3_3
SH3_6
Motif
Other DBs
NCBI-GeneID:
100676988
NCBI-ProteinID:
XP_003410916
LinkDB
All DBs
Position
Unknown
AA seq
1064 aa
AA seq
DB search
MVLGTALLPSNSYGRDQDTSLCCLCSGASESALPNLTDHFASCVEDGFEGDKTGGSSPEA
LHRPYGCDVESQALNEAIRWSSKENLLGATESDPNLFVALYDFVASGDNTLSITKGEKLR
VLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSF
LVRESESSPGQLSISLRYEGRVYHYRINTTTDGKVYVTAESRFSTLAELVHHHSTVADGL
VTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGIWKKYSLTVA
VKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRE
CSREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMT
GDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVY
DLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVAEE
LGRAASSSSVVPYLPRLPILPSKTRTLKKQVENKENIEGAQDATENSASTSAPGFIRSAQ
APSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKRNAPTPPKRSSSFREM
ENQPHKKYELTGLPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPEENVGRANDTLPKKSE
EGAAPTRERPKAKLLPRGATALPLRAPSGDPAITEKDSPGQGVAGVAVAPKSKERNGGAR
LGMAGVPEDGEQPGWSSPAKVATVLPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKF
KLLSEHQVTTSGDKDRPRRVKPKCAPPPPPVMRLLQHPSTCSDPSEEPSASSAGQPTTET
QEGGKKAASGAMPVSGKAGRPVMPPPQVPLPTSSISPAKMANGTAGTKVALRKTKQATEK
ISADKISKEALLECADLLSSAITEPVPNSQLVDTGHQLLDYCSGYVDCIPQTRNKFAFRE
AVSKLELSLQELQVSSAAAGVPGANPVLNNLLSCVQEISDVVQR
NT seq
3195 nt
NT seq
+upstream
nt +downstream
nt
atggtccttgggacagccctgcttccatctaacagttatggccgggatcaggacacatct
ctttgctgcctgtgtagtggggcctcagaatcagctctacccaacctgacagatcacttt
gccagctgtgtggaggatggatttgagggagacaagactggaggcagtagtccagaagcc
ttgcaccgcccctatggttgtgatgttgaatcccaggcactgaacgaagccatcaggtgg
agctccaaggagaacttgctcggagccactgagagtgaccctaatctctttgttgcactt
tatgattttgtagcaagtggtgataacacactaagcatcactaaaggtgaaaagctacga
gtccttggttacaaccagaatggtgagtggagtgaagttcgctctaagaatggacagggt
tgggtgccaagcaactatatcaccccggtgaacagcctggaaaaacattcctggtaccac
gggcctgtgtcccgcagtgcagcggagtatctactgagcagtctaatcaatggcagtttc
ctggtgcgagaaagtgagagcagccctgggcagctctctatctcgctcaggtatgagggg
cgtgtgtatcactacaggatcaataccaccacagatggcaaggtttacgtgactgccgaa
agccgctttagcaccttggcagagcttgttcaccatcactccaccgtggctgatgggctg
gtgacaacattacactacccagcacccaagtgtaataagcctactgtctatggtgtgtcc
cccatccacgacaaatgggaaatggaacgaacagatattaccatgaagcacaaacttggg
ggtggtcagtatggagaggtttacgttggcatctggaagaaatacagccttacagttgct
gtgaaaacattgaaggaggataccatggaggtagaggagttcctgaaagaagctgcagta
atgaaggaaatcaagcatcctaatctggtacaactattaggtgtgtgtaccttggagcca
ccgttttacatcgtgactgagtacatgccgtacgggaacctgctcgattatctccgagag
tgcagtcgagaagaggtgactgcagttgtgctgctctacatggccactcagatctcttct
gcaatggagtacttagaaaagaagaactttatccatagagatcttgcagctcgtaactgc
ttagtgggagaaaaccatgtggtaaaagtggctgacttcggcttaagtagattgatgact
ggagatacctatactgctcatgcgggagccaaatttcctattaagtggacagcaccagag
agtcttgcctacaataccttctcaatcaaatctgatgtttgggcttttggggtgctcctg
tgggaaattgctacatatggaatgtcaccatatccaggtattgacctgtctcaggtctat
gatctactagaaaaaggatatcgaatggaacaaccagaaggatgcccccctaaagtttat
gaacttatgagagcatgctggaagtggagccctgctgacaggccttcttttgctgagacg
catcaagcttttgaaactatgtttcatgactccagtatttctgaggaggtagctgaggaa
cttgggagagctgcctcctcctcatctgttgttccatacctgccccgattacctatactt
ccttccaagacccggacactgaagaaacaggtggagaacaaggagaacattgaaggggca
caagatgccacagagaattctgcctccacttctgcaccagggttcattagaagtgcacag
gcccccagtgggtccccagcactgcctcgaaagcaaagagacaagtcacccagcagcctc
ttggaagatgccaaagagacatgcttcaccagggataggaaaggaggcttcttcagctcc
ttcatgaaaaagagaaatgctcccacaccccccaaacgcagcagctccttccgagaaatg
gagaatcagccccacaagaaatatgagctcacggggcttccagagcaggataggatggca
atgactcttcccaggaactgccagaggtccaaacttcagctggaaaggacagtgtccacc
tcttctcagccagaagagaatgtgggcagggccaatgacacacttcccaaaaagtcagag
gaaggtgctgctccaaccagggagagaccaaaagccaaacttttgcccagaggagccaca
gctcttcctctcagagccccctctggggatccagccatcacagagaaggactctccaggg
cagggggtggctggagtggcagttgcccccaagagcaaggagaggaatggtggggcacga
ctcgggatggctggagttccagaggatggagagcagccagggtggtcctctccagccaag
gtggcaacagtccttccaaccactcacaaccacaaagtgccagtccttatctcacccact
ctgaaacacactccagctgatgtgcagctcattggcacagactctcaggggaacaagttc
aagctcttatctgagcatcaggtcaccacctctggagacaaggaccgaccccgacgggta
aaaccaaagtgtgccccacccccaccaccagtcatgagactactgcagcatccgtccaca
tgctcagatccttcagaagagccatctgcctcttctgcaggacagcctacgacagaaacc
caggaaggtgggaaaaaggcagcatcaggggcaatgcctgtaagtgggaaagctgggagg
ccagtgatgcctccgcctcaagtgcctctgcccacatcttccatctcgccagccaaaatg
gccaacggcacagctggtactaaagtggctctgagaaaaaccaaacaggcaactgagaaa
atctcagcagacaaaatcagcaaagaagccctgctggaatgtgctgacctactgtccagt
gcaatcacggaacctgtgcccaatagccagctggtggacactggccaccagctgctcgac
tactgctcaggctatgtggactgcatccctcaaactcgcaacaaatttgccttccgagag
gccgtgagcaaactggaactcagcctgcaggagctgcaggtgtcttcagcagctgctggt
gtccccggggcaaaccctgtccttaataacttattgtcatgtgtacaggagatcagtgat
gtggtgcagaggtag
Loxodonta africana (African savanna elephant): 100677152
Help
Entry
100677152 CDS
T04351
Gene name
ABL1
Definition
(RefSeq) tyrosine-protein kinase ABL1 isoform X1
KO
K06619
abelson tyrosine-protein kinase 1 [EC:
2.7.10.2
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav04012
ErbB signaling pathway
lav04014
Ras signaling pathway
lav04110
Cell cycle
lav04360
Axon guidance
lav04722
Neurotrophin signaling pathway
lav05200
Pathways in cancer
lav05206
MicroRNAs in cancer
lav05220
Chronic myeloid leukemia
lav05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100677152 (ABL1)
04014 Ras signaling pathway
100677152 (ABL1)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
100677152 (ABL1)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
100677152 (ABL1)
09158 Development and regeneration
04360 Axon guidance
100677152 (ABL1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100677152 (ABL1)
05206 MicroRNAs in cancer
100677152 (ABL1)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
100677152 (ABL1)
09166 Cardiovascular disease
05416 Viral myocarditis
100677152 (ABL1)
Enzymes [BR:
lav01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100677152 (ABL1)
Protein kinases [BR:
lav01001
]
Non-receptor tyrosine kinases
ABL family
100677152 (ABL1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
F_actin_bind
SH2
SH3_1
SH3_2
SH3_9
SH3_3
Kinase-like
SH3_6
Motif
Other DBs
NCBI-GeneID:
100677152
NCBI-ProteinID:
XP_003407604
UniProt:
G3SZ92
LinkDB
All DBs
Position
Unknown
AA seq
1142 aa
AA seq
DB search
MGQQPGKVLGDQRRPSLPALHFIKGAGKKESSRHGGPHCNVFVEHEALQRPVASDFEPQG
LSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCE
AQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQR
SISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRN
KPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVE
EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLL
YMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKF
PIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERP
EGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKKGVRGVAST
LLQAPELPTKTRTSRRAAEHKDSADVPETPHSKGQGESDPLDHEPTVSPLLPRKERGPQD
ASLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERKGGGEEEGQEI
SNGALAVMPSDTTEPSKSPKPSNGTSVPNGAFRSPHLWKKSNMLTSNRLAASEEESGSSS
SKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRASE
NRSDQVTRGTVTPPPRLVKKNEETADEVFKDTTESSPGSSPPSLTPKLVRRQVMMAPSSG
HPQKEEAGKSSALGTSVTAEPVPPTSRAGSGASGGGTKAPTEESRVRRHKQPSESPGRDK
GKVSRLKPAPPPPPPASVGKAGKSSQSPSHEAAGEAGAGAKAKSMTLGVDAVSSEATKPN
QLGEGIKKPVLPSIPKPQSSTKPSGTPTSPAPASSSLPSASSSLGGDQQSSTAFIPLIST
RVSLRKTRQLPERIASGTITKGVVLDSTNALCLTISKNSEQMASHSAVLEAGKNLYTFCV
SYVDSIQQMRNKFAFREAINKLENNLRELQICPATAGSGPAATQDFSKLLSSVKEISDIV
QR
NT seq
3429 nt
NT seq
+upstream
nt +downstream
nt
atggggcagcagcctggaaaagttcttggggaccaacgaaggccaagtttgcctgccctg
cactttatcaaaggagcagggaagaaggaatcatcgaggcatgggggtccacactgcaat
gtttttgtggaacatgaagcccttcagaggccggtagcatcagattttgagccccaaggt
ctgagcgaagcagctcgttggaactccaaggaaaaccttcttgctggtcccagtgaaaat
gaccccaaccttttcgttgcactgtatgattttgtggccagtggggataatactctaagc
ataactaaaggtgaaaagctccgggtcttaggctacaatcacaatggtgaatggtgtgaa
gcccaaaccaaaaatggccaagggtgggttccaagcaactacatcacgcctgtcaacagt
ctggagaaacattcctggtaccatgggcctgtgtcacgcaatgctgctgaatacctactg
agcagcggaataaatggcagcttcttggtgcgagagagcgagagcagtcctggccagagg
tccatctcgctgagatatgaaggaagggtgtaccactacaggatcaacactgcatctgat
ggcaagctctacgtctcctcagagagccgctttaatactttggccgagttggttcatcac
cattcaacagtggcagacgggctgattaccactctccattatccagcccccaagcgcaac
aagcccactgtctatggtgtgtcccccaactatgacaagtgggagatggaacgcacagac
atcaccatgaagcacaaactgggaggaggccagtatggggaggtgtatgaaggagtgtgg
aagaaatatagcctgacggtggcagtaaagaccttgaaggaggataccatggaggtggaa
gagttcttgaaagaagctgcagtaatgaaagagatcaaacaccctaatctagtgcagtta
ctcggcgtctgtacccgggagcccccgttctacataatcaccgagttcatgacctatggg
aacctgttggattacctgagggagtgcaatcggcaggaggtgaatgctgtggtgctactg
tatatggccactcagatctcgtcagccatggagtacctggagaagaaaaacttcatccac
agggatcttgctgcccgaaactgcctggtaggggaaaaccacttggtgaaggtggctgat
tttggcctgagcaggttaatgacaggtgatacctacacagcccacgccggagccaagttc
ccgatcaaatggaccgccccagaaagcctggcctacaacaagttttccattaagtctgat
gtctgggcatttggagtattgctttgggaaatagctacctatggcatgtcaccttaccca
ggaattgacctgtcccaggtgtatgagctactggaaaaagactatcgcatggaacgcccg
gaaggctgcccagagaaagtctatgaactcatgcgagcatgttggcagtggaatccctct
gaccggccctcctttgctgaaatccaccaagcctttgaaacaatgtttcaggaatccagc
atatcggatgaagtggaaaaggaactggggaaaaaaggcgtacgaggtgttgcaagtact
ttgctgcaggccccagagctgcccaccaagacgagaacctccaggagagctgcagagcac
aaagactcggctgacgtgcctgagacgccccactccaagggccagggagagagtgatcct
ctggaccatgagcccactgtgtccccattgctccctcggaaagagcgaggtccccaggat
gccagcctaaatgaagatgagcgccttctccccaaagacaaaaagaccaacttgttcagc
gccttaatcaaaaagaagaagaaaacagcccccacccctcccaaacgcagcagctccttc
cgtgagatggacggccagccagagcgcaaggggggcggtgaggaagagggccaagaaatc
agcaacggggcgctggctgtcatgccctcagacacaaccgagccaagcaagtccccaaag
cccagcaatgggaccagcgtccccaatggagccttccggtctcctcatctgtggaaaaag
tccaacatgctgaccagcaaccgattagcagccagtgaagaggagagtggcagcagctcc
agcaagcgcttcctaagatcctgctctgcctcctgtgtgccccacggagccaaggacaca
gagtggaggtcagtcacactgcctcgggatttgcagtccacaggaagacagtttgactcg
tccacatttggagggcacaaaagtgagaagccagccttgcctcggaaacgggcaagtgag
aacaggtctgaccaggtgaccaggggcacagtgacacccccacccagactggtgaagaag
aacgaggaaacagctgatgaggtcttcaaagataccacagagtccagcccaggctccagt
cctcccagtttgactccgaaacttgttcgcaggcaagtcatgatggctccttcctctggc
catccccagaaggaagaggccgggaaatccagtgccttagggacctctgtcacagctgag
ccagttccccccaccagcagagcagggtcaggtgcatctggaggtggcaccaaggcccct
actgaggagtccagagtaaggaggcacaagcagccctccgagtctccggggagagacaag
gggaaagtgtccaggctcaaacctgccccaccgcccccacccccagcctctgttgggaaa
gctggaaagtcctctcagagcccgagccatgaagcagctggggaggcaggagccggtgct
aaagcaaaatccatgaccctgggtgtggatgctgtgagcagtgaggctaccaagccaaac
cagctaggagagggcatcaaaaagcctgtgctcccttccataccaaagccacagtcatct
accaagccatcggggaccccaaccagcccagcccctgcttcctcatcattgccgtcagca
tcctcatccctgggaggggaccagcagtcctccactgccttcatccctctcatctctaca
cgtgtctctcttcggaaaacccggcagcttccggagcggattgccagtggcaccattacc
aagggtgtggtcctggacagcaccaatgccttgtgcctcaccatctccaagaactctgaa
cagatggccagccacagtgcagtgctggaagctggcaaaaacctctacacgttctgtgtg
agctacgtggattctatccagcaaatgaggaacaaattcgccttccgtgaggccatcaac
aaactggagaacaatctccgggagcttcagatctgcccggcgactgcggggagtggccca
gccgccactcaggactttagcaaactcctcagctcagtgaaagaaatcagtgacatcgta
cagaggtag
DBGET
integrated database retrieval system
