Lacticaseibacillus paracasei LC2W: LC2W_1927
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Entry
LC2W_1927 CDS
T01956
Name
(GenBank) Phosphoribosylformylglycinamidine synthase 2
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
lce
Lacticaseibacillus paracasei LC2W
Pathway
lce00230
Purine metabolism
lce01100
Metabolic pathways
lce01110
Biosynthesis of secondary metabolites
Module
lce_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
lce00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
LC2W_1927
Enzymes [BR:
lce01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
LC2W_1927
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Gene cluster
GFIT
Motif
Pfam:
AIRS
AIRS_C
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AEA54259
UniProt:
A0A422LK55
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Position
complement(1869070..1871286)
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AA seq
738 aa
AA seq
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MVHVEMSPEAIATQKPYLDLGLTEAEYDRFAELIGHQPNDTEIGLASGMWSEHCAYKYSK
PVLRQFWTKNERVLMGPGEGAGVIDIGEGKAVVFKAESHNHPSAVEPYEGAATGVGGIIR
DIFSIGAKPVAMLDSLAFGDIEQPHTQHLVDRIVAGIGGYGNAIGIPTVGGETNFDGSYT
RNPLVNAMCVGIMDKDQIQKGKAAGVGNALIYVGAKTGRDGINGASFASGDFSDEEAADR
SAVQVGDPFMEKLLMDACLEITGHHQEALVGIQDMGAAGLVSSSVEMAGKANSGMVLDLD
LIPQREAEMTPFEIMLSESQERMLLCVRAGFEQEVLAVFADYDLDAAIVGHVIAGHQYQL
YHHGKLVCDVPVSSLTDDAPIYHQQGKMPKRLAHPAADFDPIITDPVQIWTDMMAMPTIA
DKSSLYKRYDAQVQTNTVVLPGSDAAVIRIRGTHRALAMTTDSKGRYLYLDPQVGAAMSV
AEAARNLVASGAEPLGITDCLNFGDPTKPEAFYELAEAAKGIIAATKAFNAPVISGNVSL
YNETNGEAIYPTPMIGMVGLIEDLSTITTAAFKQADDLIYLVGETHGDFNGSELQKLQTG
EVTGKLFDFDLEAEKQHQHFVLKAIREHLITAAHDLSDGGLLVALAEMGFDAQLGAQINV
TLPTAWGFSETQGRFLLTVSSENQAAFEALHGPAQLIGRVQAAPEFEVTTVNQHFSASLQ
QLHTAFEEVLPCHMNQKA
NT seq
2217 nt
NT seq
+upstream
nt +downstream
nt
gtggtgcacgttgagatgagccccgaggctattgcaacccagaaaccttatttagacctt
gggctgacagaggctgaatatgatcgttttgcagaactaatcggccatcagccaaacgat
accgagatcgggttagctagcggtatgtggagcgaacactgcgcttacaaatatagcaag
ccggtgttacgccaattttggaccaaaaatgagcgcgtgttaatggggccaggtgaaggt
gctggcgtgattgatatcggcgaaggcaaagcagtggtcttcaaagccgaaagtcataat
catccctcggcagttgaaccttatgaaggcgcagcaacaggtgtgggcggcattatccgc
gacattttctcaattggtgccaagccggttgcgatgttggactcgctagcttttggcgac
attgaacagccacatacccaacatttggttgatcggattgtcgcggggattggcggttat
ggcaatgcaattggcattccgacagttggcggcgaaacaaactttgacgggagctatacc
cgaaatccgctggtcaatgccatgtgcgttggcatcatggacaaagatcaaattcaaaaa
ggtaaagctgctggtgttggcaatgctttgatttatgtcggggccaaaacaggacgtgat
ggtattaacggtgcgagctttgcttctggggatttttctgacgaagaagcagccgatcgc
tcggcggttcaagttggcgatcccttcatggaaaagctgttgatggatgcttgtctcgaa
attaccgggcatcatcaggaggcgcttgttggtattcaagatatgggtgcagctggattg
gtatcgtcaagcgtggagatggctggtaaggctaacagcgggatggtgttagatctcgac
ctgattccgcagcgtgaggccgaaatgacgccgtttgaaattatgttgtctgagtctcag
gaacggatgctgctgtgcgttcgggccggctttgagcaagaagttttggctgttttcgcc
gattatgatttggatgcggcgattgttggtcatgtgattgctggtcatcagtatcagctt
tatcaccatggcaaattggtttgcgatgtgcctgtgagttcgttgactgatgatgcgccg
atttatcatcaacaagggaaaatgccaaaacgactggcccacccggctgcggattttgac
cctatcatcactgatccggtgcaaatatggacggacatgatggcgatgccgacgattgct
gacaagtcatctttgtacaagcgttacgatgcgcaggtgcaaactaataccgtcgtcttg
ccaggcagtgatgcagccgtgattcggattcgcggtactcaccgagcactggcgatgacc
accgatagtaagggccgttacttgtatcttgatccgcaggtgggtgctgcaatgagtgtg
gctgaagctgcgcgcaatttggttgctagcggggcggaaccgcttggaatcaccgattgt
ctcaattttggcgacccaactaagcctgaggccttctacgaactggctgaggcggcgaag
ggaatcattgcggctaccaaagcctttaacgccccagttatttcaggaaatgtgtcgctg
tataacgaaacgaatggtgaggcgatctatccaaccccaatgattggcatggttggcttg
attgaggatttgagcacgatcaccacggcggctttcaagcaagcagatgatctgatttat
ctggtgggggaaactcatggtgattttaacggcagcgaactgcagaagctgcaaacagga
gaagtcactggcaagctgttcgattttgatttagaggctgaaaagcagcatcagcacttt
gttttgaaggccattcgcgagcatctaattactgcagcgcacgatttaagcgatggtggg
ttgttggtcgccttggcagagatggggtttgatgcccaacttggcgcccaaattaacgtc
acattgccgactgcttggggattttccgagacgcaaggccgcttcttgctcaccgtgtct
tctgaaaatcaggcagcatttgaagcattgcatggtccggcccaattgattggtcgagtt
caggccgcaccagaatttgaagtcacaaccgttaatcaacatttttctgcatcgttgcaa
cagctacacacagcattcgaggaggtgctcccatgccacatgaaccaaaaggcttaa
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