Leclercia sp. LSNIH1: C2U54_04105
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Entry
C2U54_04105 CDS
T05297
Symbol
metL
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase II
KO
K12525
bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:
2.7.2.4
1.1.1.3
]
Organism
lei
Leclercia sp. LSNIH1
Pathway
lei00260
Glycine, serine and threonine metabolism
lei00261
Monobactam biosynthesis
lei00270
Cysteine and methionine metabolism
lei00300
Lysine biosynthesis
lei01100
Metabolic pathways
lei01110
Biosynthesis of secondary metabolites
lei01120
Microbial metabolism in diverse environments
lei01230
Biosynthesis of amino acids
Module
lei_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
lei_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
lei_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
lei00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
C2U54_04105 (metL)
00270 Cysteine and methionine metabolism
C2U54_04105 (metL)
00300 Lysine biosynthesis
C2U54_04105 (metL)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
C2U54_04105 (metL)
Enzymes [BR:
lei01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
C2U54_04105 (metL)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
C2U54_04105 (metL)
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GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
HTH_11
Motif
Other DBs
NCBI-ProteinID:
AUU83244
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Position
complement(793979..796411)
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AA seq
810 aa
AA seq
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MSVIAQAGAKGRQLHKFGGSSLADVKCYLRVAGIMAEYSMPGDMMVVSAAGSTTNQLISW
LKLSQTDRLSAHQVQQALRRYQSELIAGLLPADVADGLISHFIQDLERLAALLDSGVTDA
VYAEVVGHGEVWSARLMAAVLQQQGLEAAWLDARDFLRAERGAQPQVDEGLSYPLLQQLL
VQHPNKRIVVTGFISRSNAGETVLLGRNGSDYSATQIGALAGVSRVTIWSDVAGVYSADP
RKVKDACLLPLLRLDEASELARLAAPVLHARTLQPVSGSDIDLQLRCSYTPDQGSTRIER
VLASGTGARIVTSHDDICLIEFLVPAGHDFKLAHKEIDLILKRAQVRPLAVGVHTDRHLL
QFCYTAEVADSALKILDEAGLPGELRLRQGLALIAMVGAGVTRNPLHCHRFWQQLKGQSV
EFTWQSEEGISLVAVMRTGPTESLIQGLHQSLFRAEKRIGLMLFGKGNIGSRWLELFARE
QTTLSARTGFEFVLAGVVDSRRSLLSYEGLDASRALAFFNDEAIEQDEESLFLWMRAHPY
DDLVVLDVTASEQLADQYLDFASHGFHVISANKLAGASNTRNYRQIHDAFEKTGRHWLYN
ATVGAGLPVNHTVRDLIDSGDSILAISGIFSGTLSWLFLQFDGTVPFTDLVDQAWQQGLT
EPDPRVDLSGKDVMRKLVILAREAGYDIEPGQVRVESLVPAGCEEGSVDHFFENGEALNE
QMLQRLEAAREMGLVLRYVARFDANGKARVGVEAVRPEHPLAALLPCDNVFAIESRWYRD
NPLVIRGPGAGRDVTAGAIQSDINRLAQLL
NT seq
2433 nt
NT seq
+upstream
nt +downstream
nt
atgagtgtgatagcgcaggcaggggcgaagggtcgccagctgcacaagtttggtggtagt
agtcttgctgatgtgaaatgttacctgcgggtcgcggggatcatggcagagtattcgatg
ccgggggacatgatggttgtctctgcggcgggcagcaccaccaaccagttgattagctgg
ctgaagttaagccagaccgatcgtctctctgcgcatcaggttcaacaagcgttacgccgt
tatcagagtgaattgatcgccgggttactgcctgccgacgtggccgatggcctgatcagc
cactttatccaggatctggagcggctggccgcgttactcgacagcggcgtgaccgatgcc
gtttacgccgaggtggtgggccacggtgaagtgtggtctgcccgtctgatggcggcggtt
ctgcaacagcaggggctggaggccgcatggctggacgcgcgggacttcctgcgtgccgaa
cgtggcgctcagccacaggttgatgaaggcctctcttatccgctgctccagcagctgctg
gtgcagcatccgaataaacgtattgtcgtgaccggctttatcagccgcagcaatgcgggt
gaaaccgtgctgctggggcgtaacggctccgactactccgcaacgcagattggtgcgctg
gcgggcgtgtcgcgcgtcacgatctggagcgacgtggcgggcgtctatagcgccgatccg
cgtaaggttaaagatgcctgcctgctgccgctgctgcgtctcgatgaagccagcgagctg
gcccgtctggcggccccggttctccacgcccgtaccctgcagccggtttccggcagcgat
atcgatctgcagctgcgctgtagctatacgccggatcagggttccacccgcattgagcgc
gtgctggcttccggcacgggggcgcgtattgtcaccagccatgacgatatctgcctgatt
gagttcctcgttcccgccggccacgatttcaaactggcgcataaagagatcgacctgatc
ctcaagcgtgcccaggtgcgcccgctggccgtgggtgtgcataccgatcgtcacctgctg
cagttctgctacaccgccgaagtggccgacagcgcgctgaagattctggatgaagcgggc
ctgccgggcgagcttcgcctgcgtcaggggctggcgctgattgcgatggtgggcgcgggc
gtcacccgtaacccactgcactgccaccgtttctggcagcagctgaaggggcagtcggtt
gaatttacctggcagtccgaggagggcatcagcctggtggcggtcatgcgcaccgggcca
acggagagtctgatccagggcctgcaccagtcgctgttccgcgccgaaaaacgcatcggt
ttgatgctgtttgggaaagggaatatcggttcccgctggctggagctgtttgcccgcgag
caaaccacgctgtcagcgcgtaccggttttgaatttgtactggcgggcgtggtggacagc
cgccgcagcctgctcagttatgaagggctggacgccagccgtgcgctggccttcttcaac
gatgaagccatcgaacaggatgaagagtcgctcttcctgtggatgcgcgcccacccctat
gatgatctggtggtgctggatgtcaccgccagcgagcagctggccgatcaatatcttgat
ttcgccagccacggcttccacgtcatcagcgctaacaagctggcgggcgccagcaatacc
cgtaactatcgtcaaatccatgacgcctttgaaaaaacgggccgtcactggctctacaat
gccaccgttggtgccggtctgccggtgaatcacaccgtgcgcgatctgatcgatagcggc
gacagcattctggcgatcagcggtatcttctccgggacgctctcctggctgttcctgcag
tttgatggcaccgtgccgttcaccgacctggtggatcaggcgtggcagcaggggctgacc
gagcctgacccccgcgttgacctctcagggaaagacgtgatgcgtaagctggtaatcctg
gcgcgtgaagcgggctacgacatcgagccgggtcaggttcgcgtggagtcgctggtgccg
gcgggttgcgaagaggggtctgtggatcacttcttcgagaacggtgaagcgttgaacgag
cagatgctacagcggctggaagcggcgcgcgaaatgggtctggtgctgcgctacgtggcg
cgttttgatgccaacggcaaggcgcgcgttggggttgaggctgtccgcccggaacatccg
ctggcggcgctgctgccgtgcgataatgtcttcgccattgaaagccgctggtatcgcgat
aacccgctggtgatccgtggtccaggtgcgggccgcgacgtgaccgccggggcgatccag
tccgatatcaaccgtctggcgcagctgctgtaa
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