Leptospira interrogans serovar Lai 56601: LA_2202
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Entry
LA_2202 CDS
T00098
Symbol
leuA
Name
(GenBank) isopropylmalate/homocitrate/citramalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
lil
Leptospira interrogans serovar Lai 56601
Pathway
lil00290
Valine, leucine and isoleucine biosynthesis
lil00620
Pyruvate metabolism
lil01100
Metabolic pathways
lil01110
Biosynthesis of secondary metabolites
lil01210
2-Oxocarboxylic acid metabolism
lil01230
Biosynthesis of amino acids
Module
lil_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
lil00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
LA_2202 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
LA_2202 (leuA)
Enzymes [BR:
lil01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
LA_2202 (leuA)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
AAN49401
UniProt:
Q8F445
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All DBs
Position
I:complement(2180227..2181813)
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AA seq
528 aa
AA seq
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MSVRLIDCLKNKTQKTGSRIFCEKDMAMDLKDYVRIFDTTLRDGEQCPGAAMTENEKLEI
ASQLATMKVDIIEAGFPVSSPVQFQAVERIARETEGPMIAALARAMKADIEAASKALQPA
KKRRIHTFIASSPIHMKYKLGKEPKEVLKMAVEAVTLCRQFVDDVEFSPEDATRSEPEFL
RELCEAVIAAGATTINIPDTVGYTTPAEYGGLFKFLLSNVRGAEKIIFSAHCHNDLGLAT
ANSLAAVQNGARQIECTINGIGERAGNTAMEEVVMAMRTRKDTFGIQTQIKTEEIARASY
LVKTITGMLVQPNKAIVGANAFAHESGIHQDGVIKHRETYEIMKPETVGLSSNRMVLGRH
SGRAGFKDRIVKLGFSPQVEELEAAYQRFLEIADRKKEIYDEDIRALFSEEARKSTGDRF
QLEGFTVSTGTKSTPTAGVRILIDGHVREESATGDGPVDAIYKAIQKTTGMDPEVSRLVI
SPVTEGQDAMAEASVTLEYKGDRVVGKGSSTDIIEACSRAYISALNRL
NT seq
1587 nt
NT seq
+upstream
nt +downstream
nt
atgagtgttcgtttaattgattgtctaaagaataaaacccaaaaaactggaagtagaatt
ttttgcgagaaagatatggcaatggatctaaaagactacgttcgtatatttgatacaact
ctcagagacggagaacaatgtcccggggctgcgatgaccgaaaacgaaaagttggaaatt
gcttctcaactcgcaacgatgaaggtagatattattgaagccggatttccagtttcttcc
cccgttcaatttcaagcagtggaaagaatcgcaagagaaaccgaagggcccatgatcgcg
gcactcgctagggcaatgaaggcggatattgaagccgcatctaaagcgcttcagcctgcg
aaaaaaagaaggattcatactttcattgcatcttctccgattcacatgaaatataaactc
ggaaaagaaccgaaagaagttttaaagatggctgtagaagcggtgacactttgcaggcaa
tttgtggacgacgtggaattttcacccgaagacgcaactaggagcgaacctgaattttta
agagaactttgtgaagcggtaattgcagcaggagctactacgatcaacattcctgacact
gtaggttataccactcctgcagaatacggtggtctttttaaatttctactcagcaacgta
agaggagccgaaaaaattatcttttctgctcattgtcataatgatttaggacttgctacc
gcaaattccttggctgcggttcaaaacggagctagacaaattgaatgtacgattaatggt
atcggagaaagagccggtaatacagcaatggaagaagtagttatggcaatgcgtactaga
aaagatacgttcggaattcaaactcaaattaaaaccgaagaaattgcccgcgcctcttat
cttgtaaaaacgattaccggaatgctcgttcaaccaaacaaagcaatcgtaggagcaaac
gcatttgcacatgaatctggaattcatcaagacggagtcatcaaacatagagaaacctac
gagattatgaaaccggaaaccgtcggtctttcttccaacagaatggttttgggaagacat
agtggtcgcgccggttttaaagatagaattgttaaactgggtttttctcctcaagtagaa
gaattggaagccgcttatcaaaggtttttagaaattgcggacagaaaaaaagaaatctat
gatgaagacattcgagcgcttttctccgaagaagctagaaaatcaaccggagatcgtttt
caattagaaggttttacggtttccaccggaaccaaaagtactcccactgcgggtgttaga
attttaattgatggtcatgtaagagaagagtctgcaaccggagacggcccggtagacgca
atctacaaagcgattcaaaaaacaaccggaatggatccggaagtctccagacttgtaatt
tctccggttaccgaaggacaagatgcaatggctgaagcctccgtgactttagaatataaa
ggagaccgtgtcgtgggaaaaggaagttctacagatattatcgaagcctgttcaagggct
tatatttccgcactcaatcgactttga
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