KEGG   Lactobacillus plantarum WCFS1: lp_1413
Entry
lp_1413           CDS       T00115                                 

Gene name
pbp2A
Definition
(RefSeq) transpeptidase-transglycosylase (penicillin binding protein 2A)
  KO
K12555  penicillin-binding protein 2A [EC:2.4.1.129 3.4.16.4]
Organism
lpl  Lactobacillus plantarum WCFS1
Pathway
lpl00550  Peptidoglycan biosynthesis
lpl01100  Metabolic pathways
lpl01501  beta-Lactam resistance
Brite
KEGG Orthology (KO) [BR:lpl00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    lp_1413 (pbp2A)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    lp_1413 (pbp2A)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:lpl01003]
    lp_1413 (pbp2A)
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:lpl01011]
    lp_1413 (pbp2A)
Enzymes [BR:lpl01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.129  peptidoglycan glycosyltransferase
     lp_1413 (pbp2A)
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.16  Serine-type carboxypeptidases
    3.4.16.4  serine-type D-Ala-D-Ala carboxypeptidase
     lp_1413 (pbp2A)
Glycosyltransferases [BR:lpl01003]
 Polysaccharide
  Bacterial polysaccharide (excluding LPS)
   lp_1413 (pbp2A)
Peptidoglycan biosynthesis and degradation proteins [BR:lpl01011]
 Peptidoglycan biosynthesis and degradation
  Glycosyltransferase/DD-Transpeptidase (Class A PBP)
   lp_1413 (pbp2A)
SSDB
Motif
Pfam: Transgly Transpeptidase Cloacin PHBC_N
Other DBs
NCBI-GeneID: 1062475
NCBI-ProteinID: YP_004889267
UniProt: F9UNG4
LinkDB
Position
1292849..1294978
AA seq 709 aa
MQKNGFWATIKDGLRVIGNWLAPYWQRFAAVVGYQWHRRQITRWLIVLVLTVILIGSAYL
TYEAKTAKVGNLQAELEKTTEIYDKDNKKAGSLYSQKGTYVHLSSISKNLQNAVISTEDR
NFYKEHGFSVKGIGRAFVLLVINKILGRDYISGGGSTLTQQLVKNAYLTQQQTFSRKFRE
IFLAIETENVYSKGQILAMYLNNAYFGHGVWGAEDASERYFGVHASELSVDQAATLAGML
SSPSGYDPINHPKASTARRNVVLNNMVANNKLSKSEYKLYSQKAMTLTNNYHYESGYNYP
YYFDAVIDEAINKYGLTESDIMNRGYKIYTSLDQDDQTQMQDSFKDSTLFPANADDGTKV
QGASIAVDPSTGGVLAVVGGRGKHVFRGFNRATQIKRQPGSTIKPLAVYTPALQNGYTYD
SNLSNKKQTFGANKYAPKNYDNVYSKSVPMYTALSQSMNIPAVWLLNKIGVNKGYQSVKK
FGLPVTKSDDNLALALGGLTTGVSPAQMTSAYTAFANGGKKTTAHFITKIVDASGNVVVD
NTKTKTKKIMSASVAKEMTSMMLGTYNSGTGAAAKPYGYSVAGKTGSTQADYSTGSGTKD
QWMIAYTPDIVVTTWIGFDTTNSTHYLKSLSENQLSSLFKNELQNILPNTNNTSFGTKDA
ATLATESNSSDSDSSDSGSSVWENVEKGANAVKNKAKDWFSKAKSFLGN
NT seq 2130 nt   +upstreamnt  +downstreamnt
atgcaaaaaaatggtttttgggccacgatcaaagacggcttacgagtcattggcaattgg
ttagcaccctattggcagcgattcgctgccgtcgtcggctaccaatggcaccggcgacaa
atcacacggtggctaattgtactcgtcttgaccgtcatcttaattgggagtgcctattta
acttatgaagccaagacggctaaagttggtaatttacaggcggagctagaaaagacaact
gaaatctatgataaggacaataaaaaggccggttcactctattcacaaaagggaacctat
gtccatttgagtagtatttcaaaaaacttacagaacgcggtaatttcgactgaagaccgt
aatttctataaagaacatggtttctcagtcaaaggaatcgggcgggcatttgtcctgctc
gttatcaataagatacttggccgtgactacattagtggtggtgggagtacgttgacgcaa
caattggtcaaaaacgcctacctaacacaacaacagaccttctcacgtaagtttcgggaa
atctttttggcgattgaaactgaaaatgtctattctaagggccaaattttagcgatgtat
ttgaataacgcttatttcggccacggtgtctggggagctgaggatgcgtctgaacgatat
tttggcgtacacgcgtcagagttgtctgttgaccaggcggcgaccttggccggaatgctg
agctcgcccagtggttatgatccaatcaatcatccgaaagcgtctacggctcgtcgaaac
gtcgtcttgaataacatggtcgctaataataagctttccaaaagtgagtataagctttat
tcgcaaaaggcgatgacgctgacgaataactaccattatgaaagtggttataattatcca
tattatttcgatgcggtgattgatgaagcaattaataagtacgggctaacggaatctgac
attatgaatcggggctataagatttatacgtcgcttgatcaagatgatcagacacagatg
caagattcttttaaggatagtacgttgttcccggccaacgcggacgatggtacgaaggtc
caaggggcctcaattgcggttgatccgtcgacgggtggtgtgttagccgtagtcggtggt
cggggcaaacacgtcttccggggctttaaccgtgcgactcagattaagcggcagccgggt
tcgacgatcaaaccgttggcagtgtatacaccagcactacaaaatggttatacgtatgat
tcgaacctttctaataagaagcaaacttttggggccaataaatatgcgcccaaaaactat
gataatgtttatagtaaatcggtcccaatgtataccgcgttatcgcaaagtatgaatatt
ccggcggtttggttattgaataagattggtgtgaataaagggtatcaatcggtgaaaaag
tttggcttaccagttaccaagtcggatgataacctggcacttgccttaggtggtttgacg
acgggggtatcacccgctcaaatgaccagtgcctatacagcgtttgcgaatggtggtaag
aaaacgacggcccactttattacgaaaattgtcgatgctagtggcaatgtcgttgtcgat
aatacgaagactaagacgaagaaaattatgtccgccagcgttgctaaagaaatgaccagt
atgatgcttggcacgtacaatagtgggaccggggctgcggccaagccgtatggatactcg
gttgctggtaagactgggagtacgcaggctgattacagtacgggttcgggaacgaaggat
cagtggatgattgcttataccccggacattgtggtcacgacctggatcggatttgatacg
acgaacagtactcattatttgaagagtttatctgaaaatcaactttcctcgttattcaag
aatgaattacaaaatattttgccgaatacgaataatactagttttggtacgaaggatgct
gcgacgctggcaaccgaatctaatagtagtgattcggatagttctgatagtggatcatcc
gtatgggaaaacgttgagaagggcgctaatgcagttaagaacaaggctaaagactggttc
tccaaagccaaaagtttccttggcaactag

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