KEGG   Legionella pneumophila subsp. pneumophila Lorraine (serogroup 1): LPO_2888Help
Entry
LPO_2888          CDS       T02175                                 

Gene name
ddlA
Definition
(GenBank) D-alanine--D-alanine ligase A
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
lpo  Legionella pneumophila subsp. pneumophila Lorraine (serogroup 1)
Pathway
lpo00473  D-Alanine metabolism
lpo00550  Peptidoglycan biosynthesis
lpo01100  Metabolic pathways
lpo01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:lpo00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00473 D-Alanine metabolism
    LPO_2888 (ddlA)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    LPO_2888 (ddlA)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    LPO_2888 (ddlA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:lpo01011]
    LPO_2888 (ddlA)
Enzymes [BR:lpo01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     LPO_2888 (ddlA)
Peptidoglycan biosynthesis and degradation proteins [BR:lpo01011]
 Precursor biosynthesis
  Amino acid ligase
   LPO_2888 (ddlA)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N CPSase_L_D2 ATP-grasp ATP-grasp_4 GARS_A
Motif
Other DBs
NCBI-ProteinID: CCD06831
LinkDB All DBs
Position
complement(3004880..3005974)
Genome map
AA seq 364 aa AA seqDB search
MSKPVNLVLLYGGKSGEHEVSLVSAASVLKHLDSEKYHIIPIAMDKSGRFHRHDYNDLLA
CSDKLPVVTEKSTPLEGLLINGRLAVDAEIVFPVVHGPLYEDGCLQGLLELAGVAYVGCD
VLSSAIGMDKDMARRLACINGLKSARYKLLSWHANASERQQFCHEVASEFGWPLFVKPCS
LGSSVGIHKANNMDELNAAVADALRYDEEILVEEFIVGREIELAVLENSIPCGQPRVSMV
GEIKVNHPDGYYSYTAKYLESSQTDLIIPAQLNNSLEEQLKQAAANIFSYLKCKGMARVD
FFVNDKTEEIYFNEINTLPGFTSISMYPKLWQATGIAYPDLLDELINLAMIHHNCRQHLV
TNYL
NT seq 1095 nt NT seq  +upstreamnt  +downstreamnt
atgtccaaacccgttaatttggttttactttatggtggaaaatcaggcgagcatgaagtg
tcattggtttctgccgcatcggttctaaaacacctggattccgagaaatatcatattata
cccattgcaatggataaaagtggtcgatttcatcgtcatgattataatgatttgctcgcc
tgttctgataaattacctgttgttactgaaaaatcaaccccattggaaggtttattaatt
aatggacgtctggcagttgatgctgaaattgtttttccagtggttcatggccctttatat
gaggatggatgtttacaaggtttacttgagttagccggtgtcgcctatgtaggatgtgac
gtattgtcttctgcaatcggaatggacaaagacatggcgaggcgactcgcatgcattaat
gggctcaaatcagcaagatataaattattatcatggcatgccaatgcgtctgaaagacaa
caattttgtcatgaagtcgcctcggagtttggttggcctctgttcgttaaaccatgctca
ctaggttccagtgtgggaattcacaaagcaaataatatggatgagctaaacgcagcagtt
gctgatgcattacgctatgatgaagaaattctggttgaagaatttattgtcggaagggaa
attgaactggcagtgttggagaacagtatcccctgtgggcaaccaagagtaagtatggtg
ggtgagataaaagtaaatcaccctgacggttattattcttatactgcgaaatatttggaa
agcagtcaaacggatttgattattccagctcaattaaataatagtctggaagaacaatta
aaacaggctgcagcgaatatttttagttatcttaaatgcaaaggcatggccagagtagat
ttttttgtaaatgataagacagaagaaatttactttaatgaaataaatacattacctgga
tttacctccataagtatgtaccccaaattgtggcaggcaactggtatagcttatcctgat
ttacttgatgaattgattaatctggcaatgattcatcataactgtcgtcaacatttggtg
acaaattacttgtga

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