KEGG   Lipotes vexillifer (Yangtze River dolphin): 103068734Help
Entry
103068734         CDS       T03090                                 

Gene name
NRAS
Definition
(RefSeq) neuroblastoma RAS viral oncogene homolog
  KO
K07828  GTPase NRas
Organism
lve  Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve01521  EGFR tyrosine kinase inhibitor resistance
lve01522  Endocrine resistance
lve04010  MAPK signaling pathway
lve04012  ErbB signaling pathway
lve04014  Ras signaling pathway
lve04015  Rap1 signaling pathway
lve04062  Chemokine signaling pathway
lve04068  FoxO signaling pathway
lve04071  Sphingolipid signaling pathway
lve04072  Phospholipase D signaling pathway
lve04137  Mitophagy - animal
lve04140  Autophagy - animal
lve04150  mTOR signaling pathway
lve04151  PI3K-Akt signaling pathway
lve04210  Apoptosis
lve04211  Longevity regulating pathway
lve04213  Longevity regulating pathway - multiple species
lve04218  Cellular senescence
lve04360  Axon guidance
lve04370  VEGF signaling pathway
lve04371  Apelin signaling pathway
lve04540  Gap junction
lve04550  Signaling pathways regulating pluripotency of stem cells
lve04625  C-type lectin receptor signaling pathway
lve04650  Natural killer cell mediated cytotoxicity
lve04660  T cell receptor signaling pathway
lve04662  B cell receptor signaling pathway
lve04664  Fc epsilon RI signaling pathway
lve04714  Thermogenesis
lve04720  Long-term potentiation
lve04722  Neurotrophin signaling pathway
lve04725  Cholinergic synapse
lve04726  Serotonergic synapse
lve04730  Long-term depression
lve04810  Regulation of actin cytoskeleton
lve04910  Insulin signaling pathway
lve04912  GnRH signaling pathway
lve04915  Estrogen signaling pathway
lve04916  Melanogenesis
lve04917  Prolactin signaling pathway
lve04919  Thyroid hormone signaling pathway
lve04921  Oxytocin signaling pathway
lve04926  Relaxin signaling pathway
lve04929  GnRH secretion
lve04933  AGE-RAGE signaling pathway in diabetic complications
lve05034  Alcoholism
lve05160  Hepatitis C
lve05161  Hepatitis B
lve05163  Human cytomegalovirus infection
lve05165  Human papillomavirus infection
lve05166  Human T-cell leukemia virus 1 infection
lve05167  Kaposi sarcoma-associated herpesvirus infection
lve05170  Human immunodeficiency virus 1 infection
lve05200  Pathways in cancer
lve05203  Viral carcinogenesis
lve05205  Proteoglycans in cancer
lve05206  MicroRNAs in cancer
lve05210  Colorectal cancer
lve05211  Renal cell carcinoma
lve05213  Endometrial cancer
lve05214  Glioma
lve05215  Prostate cancer
lve05216  Thyroid cancer
lve05218  Melanoma
lve05219  Bladder cancer
lve05220  Chronic myeloid leukemia
lve05221  Acute myeloid leukemia
lve05223  Non-small cell lung cancer
lve05224  Breast cancer
lve05225  Hepatocellular carcinoma
lve05226  Gastric cancer
lve05230  Central carbon metabolism in cancer
lve05231  Choline metabolism in cancer
lve05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:lve00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    103068734 (NRAS)
   04015 Rap1 signaling pathway
    103068734 (NRAS)
   04010 MAPK signaling pathway
    103068734 (NRAS)
   04012 ErbB signaling pathway
    103068734 (NRAS)
   04370 VEGF signaling pathway
    103068734 (NRAS)
   04371 Apelin signaling pathway
    103068734 (NRAS)
   04068 FoxO signaling pathway
    103068734 (NRAS)
   04072 Phospholipase D signaling pathway
    103068734 (NRAS)
   04071 Sphingolipid signaling pathway
    103068734 (NRAS)
   04151 PI3K-Akt signaling pathway
    103068734 (NRAS)
   04150 mTOR signaling pathway
    103068734 (NRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    103068734 (NRAS)
   04137 Mitophagy - animal
    103068734 (NRAS)
  09143 Cell growth and death
   04210 Apoptosis
    103068734 (NRAS)
   04218 Cellular senescence
    103068734 (NRAS)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    103068734 (NRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    103068734 (NRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    103068734 (NRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    103068734 (NRAS)
   04650 Natural killer cell mediated cytotoxicity
    103068734 (NRAS)
   04660 T cell receptor signaling pathway
    103068734 (NRAS)
   04662 B cell receptor signaling pathway
    103068734 (NRAS)
   04664 Fc epsilon RI signaling pathway
    103068734 (NRAS)
   04062 Chemokine signaling pathway
    103068734 (NRAS)
  09152 Endocrine system
   04910 Insulin signaling pathway
    103068734 (NRAS)
   04929 GnRH secretion
    103068734 (NRAS)
   04912 GnRH signaling pathway
    103068734 (NRAS)
   04915 Estrogen signaling pathway
    103068734 (NRAS)
   04917 Prolactin signaling pathway
    103068734 (NRAS)
   04921 Oxytocin signaling pathway
    103068734 (NRAS)
   04926 Relaxin signaling pathway
    103068734 (NRAS)
   04919 Thyroid hormone signaling pathway
    103068734 (NRAS)
   04916 Melanogenesis
    103068734 (NRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    103068734 (NRAS)
   04726 Serotonergic synapse
    103068734 (NRAS)
   04720 Long-term potentiation
    103068734 (NRAS)
   04730 Long-term depression
    103068734 (NRAS)
   04722 Neurotrophin signaling pathway
    103068734 (NRAS)
  09158 Development and regeneration
   04360 Axon guidance
    103068734 (NRAS)
  09149 Aging
   04211 Longevity regulating pathway
    103068734 (NRAS)
   04213 Longevity regulating pathway - multiple species
    103068734 (NRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    103068734 (NRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103068734 (NRAS)
   05206 MicroRNAs in cancer
    103068734 (NRAS)
   05205 Proteoglycans in cancer
    103068734 (NRAS)
   05203 Viral carcinogenesis
    103068734 (NRAS)
   05230 Central carbon metabolism in cancer
    103068734 (NRAS)
   05231 Choline metabolism in cancer
    103068734 (NRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103068734 (NRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    103068734 (NRAS)
   05225 Hepatocellular carcinoma
    103068734 (NRAS)
   05226 Gastric cancer
    103068734 (NRAS)
   05214 Glioma
    103068734 (NRAS)
   05216 Thyroid cancer
    103068734 (NRAS)
   05221 Acute myeloid leukemia
    103068734 (NRAS)
   05220 Chronic myeloid leukemia
    103068734 (NRAS)
   05218 Melanoma
    103068734 (NRAS)
   05211 Renal cell carcinoma
    103068734 (NRAS)
   05219 Bladder cancer
    103068734 (NRAS)
   05215 Prostate cancer
    103068734 (NRAS)
   05213 Endometrial cancer
    103068734 (NRAS)
   05224 Breast cancer
    103068734 (NRAS)
   05223 Non-small cell lung cancer
    103068734 (NRAS)
  09165 Substance dependence
   05034 Alcoholism
    103068734 (NRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    103068734 (NRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103068734 (NRAS)
   05170 Human immunodeficiency virus 1 infection
    103068734 (NRAS)
   05161 Hepatitis B
    103068734 (NRAS)
   05160 Hepatitis C
    103068734 (NRAS)
   05163 Human cytomegalovirus infection
    103068734 (NRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103068734 (NRAS)
   05165 Human papillomavirus infection
    103068734 (NRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103068734 (NRAS)
   01522 Endocrine resistance
    103068734 (NRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:lve04131]
    103068734 (NRAS)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:lve04147]
    103068734 (NRAS)
   04031 GTP-binding proteins [BR:lve04031]
    103068734 (NRAS)
Membrane trafficking [BR:lve04131]
 Endocytosis
  Macropinocytosis
   Ras GTPases
    103068734 (NRAS)
Exosome [BR:lve04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   103068734 (NRAS)
  Exosomal proteins of other body fluids (saliva and urine)
   103068734 (NRAS)
  Exosomal proteins of breast cancer cells
   103068734 (NRAS)
  Exosomal proteins of colorectal cancer cells
   103068734 (NRAS)
GTP-binding proteins [BR:lve04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    103068734 (NRAS)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 FeoB_N Septin Ldh_1_N ParA AAA_25
Motif
Other DBs
NCBI-GeneID: 103068734
NCBI-ProteinID: XP_007462554
UniProt: A0A340XT90
LinkDB All DBs
Position
Un
AA seq 189 aa AA seqDB search
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL
PTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQG
CMGLPCVVM
NT seq 570 nt NT seq  +upstreamnt  +downstreamnt
atgactgagtacaaactggtggtggttggagcaggtggtgttgggaaaagcgcactgaca
atccagctgatccagaaccactttgtagatgaatatgatcccaccatagaggattcttac
cgaaaacaggtggttatagatggtgaaacctgtctgttggacatactggatacagctgga
caagaggagtacagtgccatgagagaccaatacatgaggacaggcgaaggcttcctttgt
gtatttgccatcaataatagcaaatcatttgcagatattaacctctacagggaacagatt
aagcgtgtaaaagactcagatgatgtacctatggtgctagtaggaaacaagtgtgatttg
ccaacaaggacagttgacacaaaacaagcccatgaactggccaagagttatgggattcca
ttcattgaaacctcagccaagaccagacagggtgttgaagatgccttttacacactggta
agagaaatacgtcagtaccgaatgaaaaaactcaacagcagtgatgatgggactcaaggt
tgtatgggattgccatgtgtagtgatgtaa

KEGG   Lipotes vexillifer (Yangtze River dolphin): 103069562Help
Entry
103069562         CDS       T03090                                 

Gene name
RRAS2
Definition
(RefSeq) related RAS viral (r-ras) oncogene homolog 2
  KO
K07830  Ras-related protein R-Ras2
Organism
lve  Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve04010  MAPK signaling pathway
lve04014  Ras signaling pathway
lve04024  cAMP signaling pathway
lve04072  Phospholipase D signaling pathway
lve04137  Mitophagy - animal
lve04140  Autophagy - animal
lve04218  Cellular senescence
lve04371  Apelin signaling pathway
lve04625  C-type lectin receptor signaling pathway
lve04810  Regulation of actin cytoskeleton
lve05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:lve00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    103069562 (RRAS2)
   04010 MAPK signaling pathway
    103069562 (RRAS2)
   04371 Apelin signaling pathway
    103069562 (RRAS2)
   04072 Phospholipase D signaling pathway
    103069562 (RRAS2)
   04024 cAMP signaling pathway
    103069562 (RRAS2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    103069562 (RRAS2)
   04137 Mitophagy - animal
    103069562 (RRAS2)
  09143 Cell growth and death
   04218 Cellular senescence
    103069562 (RRAS2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    103069562 (RRAS2)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    103069562 (RRAS2)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    103069562 (RRAS2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:lve04147]
    103069562 (RRAS2)
   04031 GTP-binding proteins [BR:lve04031]
    103069562 (RRAS2)
Exosome [BR:lve04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   103069562 (RRAS2)
  Exosomal proteins of bladder cancer cells
   103069562 (RRAS2)
GTP-binding proteins [BR:lve04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    103069562 (RRAS2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Ras Arf Roc DUF2075 NPHI_C RsgA_GTPase FeThRed_B
Motif
Other DBs
NCBI-GeneID: 103069562
NCBI-ProteinID: XP_007460279
UniProt: A0A340XLY4
LinkDB All DBs
Position
Un
AA seq 127 aa AA seqDB search
MREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQV
TQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQEQECPPSPEPTRKEKDKK
GCHCVIF
NT seq 384 nt NT seq  +upstreamnt  +downstreamnt
atgagagaacagtatatgagaactggcgagggcttcctgttggtcttttcagtcacagat
agaggcagttttgaagaaatctataagtttcagagacagattctcagagtaaaggatcgt
gatgagtttccaatgattttaattggtaataaagcagatctggatcatcagagacaggta
acgcaggaagaaggacagcagttagcgcgacaacttaaggtaacatacatggaggcgtca
gcaaagattaggatgaatgtagatcaagctttccatgaacttgtccgggttataaggaaa
tttcaagagcaggaatgtcctccttcaccagaaccaacacggaaagaaaaagacaagaaa
ggctgccactgtgtcattttctaa

KEGG   Lipotes vexillifer (Yangtze River dolphin): 103070662Help
Entry
103070662         CDS       T03090                                 

Gene name
RRAS
Definition
(RefSeq) related RAS viral (r-ras) oncogene homolog
  KO
K07829  Ras-related protein R-Ras
Organism
lve  Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve04010  MAPK signaling pathway
lve04014  Ras signaling pathway
lve04015  Rap1 signaling pathway
lve04024  cAMP signaling pathway
lve04072  Phospholipase D signaling pathway
lve04137  Mitophagy - animal
lve04140  Autophagy - animal
lve04218  Cellular senescence
lve04360  Axon guidance
lve04371  Apelin signaling pathway
lve04625  C-type lectin receptor signaling pathway
lve04810  Regulation of actin cytoskeleton
lve05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:lve00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    103070662 (RRAS)
   04015 Rap1 signaling pathway
    103070662 (RRAS)
   04010 MAPK signaling pathway
    103070662 (RRAS)
   04371 Apelin signaling pathway
    103070662 (RRAS)
   04072 Phospholipase D signaling pathway
    103070662 (RRAS)
   04024 cAMP signaling pathway
    103070662 (RRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    103070662 (RRAS)
   04137 Mitophagy - animal
    103070662 (RRAS)
  09143 Cell growth and death
   04218 Cellular senescence
    103070662 (RRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    103070662 (RRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    103070662 (RRAS)
  09158 Development and regeneration
   04360 Axon guidance
    103070662 (RRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    103070662 (RRAS)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:lve04031]
    103070662 (RRAS)
GTP-binding proteins [BR:lve04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    103070662 (RRAS)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Ras Roc Arf GTP_EFTU ATP_bind_1 MMR_HSR1 AAA_22
Motif
Other DBs
NCBI-GeneID: 103070662
NCBI-ProteinID: XP_007463432
UniProt: A0A340XTA5
LinkDB All DBs
Position
Un
AA seq 218 aa AA seqDB search
MSSGAASGTGRGRPRGGGPGPGDPPPSETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDP
TIEDSYTKICMVDGVPARLDILDTAGQEEFGAMREQYMRAGHGFLLVFAINDRQSFNEVG
KLFTQILRVKDRDDFPIVLVGNKADLETQRQVPRSEASTFSASHHVAYFEASAKLRLNVD
EAFEQLVRAVRKYQEQELPPRPPSAPRKKDRGCPCALL
NT seq 657 nt NT seq  +upstreamnt  +downstreamnt
atgagcagcggggcggcgtccgggacagggcgggggcggccccggggcggggggccgggg
cccggggaccccccacccagcgagacacacaagctggtggtcgtgggcggcggcggcgtg
ggcaagagcgcgctgaccatccagttcatccagtcttacttcgtgtctgactacgacccc
actattgaagactcctacacgaagatctgcatggtggatggtgtcccagcccggctagac
attctggacaccgctggccaggaggagttcggtgctatgcgggagcagtacatgcgtgcc
ggccatggcttcctgctggtgtttgccattaacgaccggcagagtttcaacgaggtgggc
aagctcttcacgcagatcctccgagtcaaggaccgagatgacttccccatcgtgttggtc
gggaacaaggcagatctggagacacagcgccaggtcccccgatccgaagcctccaccttc
agcgcctcccaccatgtggcctacttcgaggcctcggccaaactgcgcctcaatgtggac
gaggccttcgagcagctggtgcgggccgtccggaagtaccaggaacaagagctcccgccc
cgcccgcccagcgcccccaggaagaaggacaggggctgcccctgcgccctcctgtag

KEGG   Lipotes vexillifer (Yangtze River dolphin): 103076043Help
Entry
103076043         CDS       T03090                                 

Gene name
HRAS
Definition
(RefSeq) HRas proto-oncogene, GTPase
  KO
K02833  GTPase HRas
Organism
lve  Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve01521  EGFR tyrosine kinase inhibitor resistance
lve01522  Endocrine resistance
lve04010  MAPK signaling pathway
lve04012  ErbB signaling pathway
lve04014  Ras signaling pathway
lve04015  Rap1 signaling pathway
lve04062  Chemokine signaling pathway
lve04068  FoxO signaling pathway
lve04071  Sphingolipid signaling pathway
lve04072  Phospholipase D signaling pathway
lve04137  Mitophagy - animal
lve04140  Autophagy - animal
lve04144  Endocytosis
lve04150  mTOR signaling pathway
lve04151  PI3K-Akt signaling pathway
lve04210  Apoptosis
lve04211  Longevity regulating pathway
lve04213  Longevity regulating pathway - multiple species
lve04218  Cellular senescence
lve04360  Axon guidance
lve04370  VEGF signaling pathway
lve04371  Apelin signaling pathway
lve04510  Focal adhesion
lve04540  Gap junction
lve04550  Signaling pathways regulating pluripotency of stem cells
lve04625  C-type lectin receptor signaling pathway
lve04630  Jak-STAT signaling pathway
lve04650  Natural killer cell mediated cytotoxicity
lve04660  T cell receptor signaling pathway
lve04662  B cell receptor signaling pathway
lve04664  Fc epsilon RI signaling pathway
lve04714  Thermogenesis
lve04720  Long-term potentiation
lve04722  Neurotrophin signaling pathway
lve04725  Cholinergic synapse
lve04726  Serotonergic synapse
lve04730  Long-term depression
lve04810  Regulation of actin cytoskeleton
lve04910  Insulin signaling pathway
lve04912  GnRH signaling pathway
lve04915  Estrogen signaling pathway
lve04916  Melanogenesis
lve04917  Prolactin signaling pathway
lve04919  Thyroid hormone signaling pathway
lve04921  Oxytocin signaling pathway
lve04926  Relaxin signaling pathway
lve04929  GnRH secretion
lve04933  AGE-RAGE signaling pathway in diabetic complications
lve05034  Alcoholism
lve05160  Hepatitis C
lve05161  Hepatitis B
lve05163  Human cytomegalovirus infection
lve05165  Human papillomavirus infection
lve05166  Human T-cell leukemia virus 1 infection
lve05167  Kaposi sarcoma-associated herpesvirus infection
lve05170  Human immunodeficiency virus 1 infection
lve05200  Pathways in cancer
lve05203  Viral carcinogenesis
lve05205  Proteoglycans in cancer
lve05206  MicroRNAs in cancer
lve05210  Colorectal cancer
lve05211  Renal cell carcinoma
lve05213  Endometrial cancer
lve05214  Glioma
lve05215  Prostate cancer
lve05216  Thyroid cancer
lve05218  Melanoma
lve05219  Bladder cancer
lve05220  Chronic myeloid leukemia
lve05221  Acute myeloid leukemia
lve05223  Non-small cell lung cancer
lve05224  Breast cancer
lve05225  Hepatocellular carcinoma
lve05226  Gastric cancer
lve05230  Central carbon metabolism in cancer
lve05231  Choline metabolism in cancer
lve05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:lve00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    103076043 (HRAS)
   04015 Rap1 signaling pathway
    103076043 (HRAS)
   04010 MAPK signaling pathway
    103076043 (HRAS)
   04012 ErbB signaling pathway
    103076043 (HRAS)
   04370 VEGF signaling pathway
    103076043 (HRAS)
   04371 Apelin signaling pathway
    103076043 (HRAS)
   04630 Jak-STAT signaling pathway
    103076043 (HRAS)
   04068 FoxO signaling pathway
    103076043 (HRAS)
   04072 Phospholipase D signaling pathway
    103076043 (HRAS)
   04071 Sphingolipid signaling pathway
    103076043 (HRAS)
   04151 PI3K-Akt signaling pathway
    103076043 (HRAS)
   04150 mTOR signaling pathway
    103076043 (HRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    103076043 (HRAS)
   04140 Autophagy - animal
    103076043 (HRAS)
   04137 Mitophagy - animal
    103076043 (HRAS)
  09143 Cell growth and death
   04210 Apoptosis
    103076043 (HRAS)
   04218 Cellular senescence
    103076043 (HRAS)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103076043 (HRAS)
   04540 Gap junction
    103076043 (HRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    103076043 (HRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    103076043 (HRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    103076043 (HRAS)
   04650 Natural killer cell mediated cytotoxicity
    103076043 (HRAS)
   04660 T cell receptor signaling pathway
    103076043 (HRAS)
   04662 B cell receptor signaling pathway
    103076043 (HRAS)
   04664 Fc epsilon RI signaling pathway
    103076043 (HRAS)
   04062 Chemokine signaling pathway
    103076043 (HRAS)
  09152 Endocrine system
   04910 Insulin signaling pathway
    103076043 (HRAS)
   04929 GnRH secretion
    103076043 (HRAS)
   04912 GnRH signaling pathway
    103076043 (HRAS)
   04915 Estrogen signaling pathway
    103076043 (HRAS)
   04917 Prolactin signaling pathway
    103076043 (HRAS)
   04921 Oxytocin signaling pathway
    103076043 (HRAS)
   04926 Relaxin signaling pathway
    103076043 (HRAS)
   04919 Thyroid hormone signaling pathway
    103076043 (HRAS)
   04916 Melanogenesis
    103076043 (HRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    103076043 (HRAS)
   04726 Serotonergic synapse
    103076043 (HRAS)
   04720 Long-term potentiation
    103076043 (HRAS)
   04730 Long-term depression
    103076043 (HRAS)
   04722 Neurotrophin signaling pathway
    103076043 (HRAS)
  09158 Development and regeneration
   04360 Axon guidance
    103076043 (HRAS)
  09149 Aging
   04211 Longevity regulating pathway
    103076043 (HRAS)
   04213 Longevity regulating pathway - multiple species
    103076043 (HRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    103076043 (HRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103076043 (HRAS)
   05206 MicroRNAs in cancer
    103076043 (HRAS)
   05205 Proteoglycans in cancer
    103076043 (HRAS)
   05203 Viral carcinogenesis
    103076043 (HRAS)
   05230 Central carbon metabolism in cancer
    103076043 (HRAS)
   05231 Choline metabolism in cancer
    103076043 (HRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103076043 (HRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    103076043 (HRAS)
   05225 Hepatocellular carcinoma
    103076043 (HRAS)
   05226 Gastric cancer
    103076043 (HRAS)
   05214 Glioma
    103076043 (HRAS)
   05216 Thyroid cancer
    103076043 (HRAS)
   05221 Acute myeloid leukemia
    103076043 (HRAS)
   05220 Chronic myeloid leukemia
    103076043 (HRAS)
   05218 Melanoma
    103076043 (HRAS)
   05211 Renal cell carcinoma
    103076043 (HRAS)
   05219 Bladder cancer
    103076043 (HRAS)
   05215 Prostate cancer
    103076043 (HRAS)
   05213 Endometrial cancer
    103076043 (HRAS)
   05224 Breast cancer
    103076043 (HRAS)
   05223 Non-small cell lung cancer
    103076043 (HRAS)
  09165 Substance dependence
   05034 Alcoholism
    103076043 (HRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    103076043 (HRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103076043 (HRAS)
   05170 Human immunodeficiency virus 1 infection
    103076043 (HRAS)
   05161 Hepatitis B
    103076043 (HRAS)
   05160 Hepatitis C
    103076043 (HRAS)
   05163 Human cytomegalovirus infection
    103076043 (HRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103076043 (HRAS)
   05165 Human papillomavirus infection
    103076043 (HRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103076043 (HRAS)
   01522 Endocrine resistance
    103076043 (HRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:lve04131]
    103076043 (HRAS)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:lve04147]
    103076043 (HRAS)
   04031 GTP-binding proteins [BR:lve04031]
    103076043 (HRAS)
Membrane trafficking [BR:lve04131]
 Endocytosis
  Macropinocytosis
   Ras GTPases
    103076043 (HRAS)
Exosome [BR:lve04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   103076043 (HRAS)
  Exosomal proteins of colorectal cancer cells
   103076043 (HRAS)
GTP-binding proteins [BR:lve04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    103076043 (HRAS)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 FeoB_N Gtr1_RagA G-alpha AAA_22 ATP_bind_1 Septin Ldh_1_N AAA_25 AAA_16
Motif
Other DBs
NCBI-GeneID: 103076043
NCBI-ProteinID: XP_007465975
UniProt: A0A340Y3B4
LinkDB All DBs
Position
Un
AA seq 189 aa AA seqDB search
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNAKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL
AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKARKLSPPDEGGPG
CLSCRCLLS
NT seq 570 nt NT seq  +upstreamnt  +downstreamnt
atgacggagtataagctcgtggtggtgggcgctggaggggtagggaagagcgccctgacc
atccagctcatccagaaccactttgtggatgagtacgaccccaccatagaggactcctac
cggaagcaagtggtcatcgatggggagacgtgcctgctggacatcctggacacggcgggc
caggaggagtacagcgccatgcgggaccagtacatgcgcactggggagggcttcctttgt
gtgtttgccatcaacaatgccaagtccttcgaggacatccaccagtacagggagcagatc
aagcgggtgaaggactcggacgacgtgcccatggtgctggtggggaacaagtgtgacctg
gccgcgcgcaccgtggagtctcggcaggcccaggacctcgcccgcagctacggcatcccc
tacatcgagacttcggccaagacgcgccagggcgtggaggatgccttctacacgctggtg
cgcgagatccggcagcacaaggcgcgcaagctgagcccgcctgacgagggtggcccgggc
tgcctgagctgcaggtgcctgctctcctga

KEGG   Lipotes vexillifer (Yangtze River dolphin): 103077579Help
Entry
103077579         CDS       T03090                                 

Gene name
KRAS
Definition
(RefSeq) KRAS proto-oncogene, GTPase
  KO
K07827  GTPase KRas
Organism
lve  Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve01521  EGFR tyrosine kinase inhibitor resistance
lve01522  Endocrine resistance
lve04010  MAPK signaling pathway
lve04012  ErbB signaling pathway
lve04014  Ras signaling pathway
lve04015  Rap1 signaling pathway
lve04062  Chemokine signaling pathway
lve04068  FoxO signaling pathway
lve04071  Sphingolipid signaling pathway
lve04072  Phospholipase D signaling pathway
lve04137  Mitophagy - animal
lve04140  Autophagy - animal
lve04150  mTOR signaling pathway
lve04151  PI3K-Akt signaling pathway
lve04210  Apoptosis
lve04211  Longevity regulating pathway
lve04213  Longevity regulating pathway - multiple species
lve04218  Cellular senescence
lve04360  Axon guidance
lve04370  VEGF signaling pathway
lve04371  Apelin signaling pathway
lve04540  Gap junction
lve04550  Signaling pathways regulating pluripotency of stem cells
lve04625  C-type lectin receptor signaling pathway
lve04650  Natural killer cell mediated cytotoxicity
lve04660  T cell receptor signaling pathway
lve04662  B cell receptor signaling pathway
lve04664  Fc epsilon RI signaling pathway
lve04714  Thermogenesis
lve04720  Long-term potentiation
lve04722  Neurotrophin signaling pathway
lve04725  Cholinergic synapse
lve04726  Serotonergic synapse
lve04730  Long-term depression
lve04810  Regulation of actin cytoskeleton
lve04910  Insulin signaling pathway
lve04912  GnRH signaling pathway
lve04914  Progesterone-mediated oocyte maturation
lve04915  Estrogen signaling pathway
lve04916  Melanogenesis
lve04917  Prolactin signaling pathway
lve04919  Thyroid hormone signaling pathway
lve04921  Oxytocin signaling pathway
lve04926  Relaxin signaling pathway
lve04929  GnRH secretion
lve04933  AGE-RAGE signaling pathway in diabetic complications
lve04960  Aldosterone-regulated sodium reabsorption
lve05034  Alcoholism
lve05160  Hepatitis C
lve05161  Hepatitis B
lve05163  Human cytomegalovirus infection
lve05165  Human papillomavirus infection
lve05166  Human T-cell leukemia virus 1 infection
lve05167  Kaposi sarcoma-associated herpesvirus infection
lve05170  Human immunodeficiency virus 1 infection
lve05200  Pathways in cancer
lve05203  Viral carcinogenesis
lve05205  Proteoglycans in cancer
lve05206  MicroRNAs in cancer
lve05210  Colorectal cancer
lve05211  Renal cell carcinoma
lve05212  Pancreatic cancer
lve05213  Endometrial cancer
lve05214  Glioma
lve05215  Prostate cancer
lve05216  Thyroid cancer
lve05218  Melanoma
lve05219  Bladder cancer
lve05220  Chronic myeloid leukemia
lve05221  Acute myeloid leukemia
lve05223  Non-small cell lung cancer
lve05224  Breast cancer
lve05225  Hepatocellular carcinoma
lve05226  Gastric cancer
lve05230  Central carbon metabolism in cancer
lve05231  Choline metabolism in cancer
lve05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:lve00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    103077579 (KRAS)
   04015 Rap1 signaling pathway
    103077579 (KRAS)
   04010 MAPK signaling pathway
    103077579 (KRAS)
   04012 ErbB signaling pathway
    103077579 (KRAS)
   04370 VEGF signaling pathway
    103077579 (KRAS)
   04371 Apelin signaling pathway
    103077579 (KRAS)
   04068 FoxO signaling pathway
    103077579 (KRAS)
   04072 Phospholipase D signaling pathway
    103077579 (KRAS)
   04071 Sphingolipid signaling pathway
    103077579 (KRAS)
   04151 PI3K-Akt signaling pathway
    103077579 (KRAS)
   04150 mTOR signaling pathway
    103077579 (KRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    103077579 (KRAS)
   04137 Mitophagy - animal
    103077579 (KRAS)
  09143 Cell growth and death
   04210 Apoptosis
    103077579 (KRAS)
   04218 Cellular senescence
    103077579 (KRAS)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    103077579 (KRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    103077579 (KRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    103077579 (KRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    103077579 (KRAS)
   04650 Natural killer cell mediated cytotoxicity
    103077579 (KRAS)
   04660 T cell receptor signaling pathway
    103077579 (KRAS)
   04662 B cell receptor signaling pathway
    103077579 (KRAS)
   04664 Fc epsilon RI signaling pathway
    103077579 (KRAS)
   04062 Chemokine signaling pathway
    103077579 (KRAS)
  09152 Endocrine system
   04910 Insulin signaling pathway
    103077579 (KRAS)
   04929 GnRH secretion
    103077579 (KRAS)
   04912 GnRH signaling pathway
    103077579 (KRAS)
   04915 Estrogen signaling pathway
    103077579 (KRAS)
   04914 Progesterone-mediated oocyte maturation
    103077579 (KRAS)
   04917 Prolactin signaling pathway
    103077579 (KRAS)
   04921 Oxytocin signaling pathway
    103077579 (KRAS)
   04926 Relaxin signaling pathway
    103077579 (KRAS)
   04919 Thyroid hormone signaling pathway
    103077579 (KRAS)
   04916 Melanogenesis
    103077579 (KRAS)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    103077579 (KRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    103077579 (KRAS)
   04726 Serotonergic synapse
    103077579 (KRAS)
   04720 Long-term potentiation
    103077579 (KRAS)
   04730 Long-term depression
    103077579 (KRAS)
   04722 Neurotrophin signaling pathway
    103077579 (KRAS)
  09158 Development and regeneration
   04360 Axon guidance
    103077579 (KRAS)
  09149 Aging
   04211 Longevity regulating pathway
    103077579 (KRAS)
   04213 Longevity regulating pathway - multiple species
    103077579 (KRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    103077579 (KRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103077579 (KRAS)
   05206 MicroRNAs in cancer
    103077579 (KRAS)
   05205 Proteoglycans in cancer
    103077579 (KRAS)
   05203 Viral carcinogenesis
    103077579 (KRAS)
   05230 Central carbon metabolism in cancer
    103077579 (KRAS)
   05231 Choline metabolism in cancer
    103077579 (KRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103077579 (KRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    103077579 (KRAS)
   05212 Pancreatic cancer
    103077579 (KRAS)
   05225 Hepatocellular carcinoma
    103077579 (KRAS)
   05226 Gastric cancer
    103077579 (KRAS)
   05214 Glioma
    103077579 (KRAS)
   05216 Thyroid cancer
    103077579 (KRAS)
   05221 Acute myeloid leukemia
    103077579 (KRAS)
   05220 Chronic myeloid leukemia
    103077579 (KRAS)
   05218 Melanoma
    103077579 (KRAS)
   05211 Renal cell carcinoma
    103077579 (KRAS)
   05219 Bladder cancer
    103077579 (KRAS)
   05215 Prostate cancer
    103077579 (KRAS)
   05213 Endometrial cancer
    103077579 (KRAS)
   05224 Breast cancer
    103077579 (KRAS)
   05223 Non-small cell lung cancer
    103077579 (KRAS)
  09165 Substance dependence
   05034 Alcoholism
    103077579 (KRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    103077579 (KRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103077579 (KRAS)
   05170 Human immunodeficiency virus 1 infection
    103077579 (KRAS)
   05161 Hepatitis B
    103077579 (KRAS)
   05160 Hepatitis C
    103077579 (KRAS)
   05163 Human cytomegalovirus infection
    103077579 (KRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103077579 (KRAS)
   05165 Human papillomavirus infection
    103077579 (KRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103077579 (KRAS)
   01522 Endocrine resistance
    103077579 (KRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:lve04131]
    103077579 (KRAS)
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:lve04031]
    103077579 (KRAS)
Membrane trafficking [BR:lve04131]
 Endocytosis
  Macropinocytosis
   Ras GTPases
    103077579 (KRAS)
GTP-binding proteins [BR:lve04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    103077579 (KRAS)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 MeaB G-alpha FeoB_N ATP_bind_1 Septin AAA_25
Motif
Other DBs
NCBI-GeneID: 103077579
NCBI-ProteinID: XP_007446341
UniProt: A0A340WCQ7
LinkDB All DBs
Position
Un
AA seq 188 aa AA seqDB search
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL
PSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKEGKKKKKK
SKTKCIIM
NT seq 567 nt NT seq  +upstreamnt  +downstreamnt
atgactgaatataaacttgtggtagttggagctggtggcgtaggcaagagtgccttgacg
atacagctaattcagaatcactttgtggatgaatatgatcctacgatagaggattcctac
agaaaacaagtagtaattgatggagaaacctgtctcttggatattctcgacacagcaggt
caagaggagtacagtgcaatgagggaccagtacatgaggactggggagggctttctttgt
gtatttgccataaataatactaaatcatttgaagatattcaccattatagagaacaaata
aaaagagttaaagactctgaagatgtacctatggttctagtaggaaataaatgtgatttg
ccttctagaacagtagacacaaaacaggctcaggacttagcaagaagttatggaattcct
tttattgaaacatctgcaaagacaagacagggtgttgacgatgccttctatacattagtt
cgagaaattcgaaaacataaagaaaagatgagcaaagaaggtaaaaagaagaaaaagaag
tcaaagacaaagtgtataattatgtaa

KEGG   Lipotes vexillifer (Yangtze River dolphin): 103087313Help
Entry
103087313         CDS       T03090                                 

Gene name
MRAS
Definition
(RefSeq) muscle RAS oncogene homolog
  KO
K07831  Ras-related protein M-Ras
Organism
lve  Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve04010  MAPK signaling pathway
lve04014  Ras signaling pathway
lve04015  Rap1 signaling pathway
lve04072  Phospholipase D signaling pathway
lve04137  Mitophagy - animal
lve04140  Autophagy - animal
lve04218  Cellular senescence
lve04371  Apelin signaling pathway
lve04625  C-type lectin receptor signaling pathway
lve04810  Regulation of actin cytoskeleton
lve05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:lve00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    103087313 (MRAS)
   04015 Rap1 signaling pathway
    103087313 (MRAS)
   04010 MAPK signaling pathway
    103087313 (MRAS)
   04371 Apelin signaling pathway
    103087313 (MRAS)
   04072 Phospholipase D signaling pathway
    103087313 (MRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    103087313 (MRAS)
   04137 Mitophagy - animal
    103087313 (MRAS)
  09143 Cell growth and death
   04218 Cellular senescence
    103087313 (MRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    103087313 (MRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    103087313 (MRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    103087313 (MRAS)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:lve04031]
    103087313 (MRAS)
GTP-binding proteins [BR:lve04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    103087313 (MRAS)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Ras Roc GTP_EFTU Arf RsgA_GTPase MMR_HSR1 Gtr1_RagA ATP_bind_1 AAA_16 MMR_HSR1_Xtn
Motif
Other DBs
NCBI-GeneID: 103087313
NCBI-ProteinID: XP_007464419
UniProt: A0A340XZ13
LinkDB All DBs
Position
Un
AA seq 208 aa AA seqDB search
MATSAVPSDNLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQW
AILDVLDTAGQEEFSAMREQYMRTGDGFLIVFSVTDKASFEHVDRFHQLILRVKDRESFP
MILVANKVDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDRAFHDLVRVIRQQIP
ERSQKKKKKTKWRGDRATGTHKPQCVIL
NT seq 627 nt NT seq  +upstreamnt  +downstreamnt
atggcgacaagtgccgtccccagcgacaacctccccacgtacaagctggtggtggtggga
gacgggggtgtgggcaagagcgccctcaccatccagtttttccagaagatctttgtgcct
gactatgaccccaccatcgaagactcctacctgaagcatacagagattgacaaccagtgg
gccatcttggacgttctggacacagccggacaggaggagttcagcgccatgcgggagcag
tacatgcgcacgggggacggcttcctcatcgtcttctcggtcacggacaaggccagcttc
gagcacgtggaccgcttccaccagctcatcctgcgcgtcaaggacagggagtcatttccg
atgatccttgtggccaacaaggtcgatttgatgcatttgaggaaaatcaccagggagcaa
ggaaaagaaatggccaccaaacacaatattccgtacatagaaaccagtgccaaggaccca
cctctcaacgtcgacagagccttccatgacctggttagagtaattaggcaacagattccg
gaaaggagccagaagaagaagaagaaaaccaaatggcggggagaccgggccactggcacc
cacaaaccgcagtgcgtgatactgtga

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