Lipotes vexillifer (Yangtze River dolphin): 103070260 Help Entry 103070260         CDS       T03090                                  Gene name MAPK1 Definition (RefSeq) mitogen-activated protein kinase 1   KO K04371   mitogen-activated protein kinase 1/3 [EC:2.7.11.24] Organism lve  Lipotes vexillifer (Yangtze River dolphin) Pathway lve01521   EGFR tyrosine kinase inhibitor resistance lve01522   Endocrine resistance lve01524   Platinum drug resistance lve04010   MAPK signaling pathway lve04012   ErbB signaling pathway lve04014   Ras signaling pathway lve04015   Rap1 signaling pathway lve04022   cGMP-PKG signaling pathway lve04024   cAMP signaling pathway lve04062   Chemokine signaling pathway lve04066   HIF-1 signaling pathway lve04068   FoxO signaling pathway lve04071   Sphingolipid signaling pathway lve04072   Phospholipase D signaling pathway lve04114   Oocyte meiosis lve04140   Autophagy - animal lve04150   mTOR signaling pathway lve04151   PI3K-Akt signaling pathway lve04210   Apoptosis lve04218   Cellular senescence lve04261   Adrenergic signaling in cardiomyocytes lve04270   Vascular smooth muscle contraction lve04350   TGF-beta signaling pathway lve04360   Axon guidance lve04370   VEGF signaling pathway lve04371   Apelin signaling pathway lve04380   Osteoclast differentiation lve04510   Focal adhesion lve04520   Adherens junction lve04540   Gap junction lve04550   Signaling pathways regulating pluripotency of stem cells lve04611   Platelet activation lve04620   Toll-like receptor signaling pathway lve04621   NOD-like receptor signaling pathway lve04625   C-type lectin receptor signaling pathway lve04650   Natural killer cell mediated cytotoxicity lve04657   IL-17 signaling pathway lve04658   Th1 and Th2 cell differentiation lve04659   Th17 cell differentiation lve04660   T cell receptor signaling pathway lve04662   B cell receptor signaling pathway lve04664   Fc epsilon RI signaling pathway lve04666   Fc gamma R-mediated phagocytosis lve04668   TNF signaling pathway lve04713   Circadian entrainment lve04720   Long-term potentiation lve04722   Neurotrophin signaling pathway lve04723   Retrograde endocannabinoid signaling lve04724   Glutamatergic synapse lve04725   Cholinergic synapse lve04726   Serotonergic synapse lve04730   Long-term depression lve04810   Regulation of actin cytoskeleton lve04910   Insulin signaling pathway lve04912   GnRH signaling pathway lve04914   Progesterone-mediated oocyte maturation lve04915   Estrogen signaling pathway lve04916   Melanogenesis lve04917   Prolactin signaling pathway lve04919   Thyroid hormone signaling pathway lve04921   Oxytocin signaling pathway lve04926   Relaxin signaling pathway lve04928   Parathyroid hormone synthesis, secretion and action lve04929   GnRH secretion lve04930   Type II diabetes mellitus lve04933   AGE-RAGE signaling pathway in diabetic complications lve04934   Cushing syndrome lve04935   Growth hormone synthesis, secretion and action lve04960   Aldosterone-regulated sodium reabsorption lve05010   Alzheimer disease lve05020   Prion disease lve05022   Pathways of neurodegeneration - multiple diseases lve05034   Alcoholism lve05132   Salmonella infection lve05133   Pertussis lve05135   Yersinia infection lve05140   Leishmaniasis lve05142   Chagas disease lve05145   Toxoplasmosis lve05152   Tuberculosis lve05160   Hepatitis C lve05161   Hepatitis B lve05163   Human cytomegalovirus infection lve05164   Influenza A lve05165   Human papillomavirus infection lve05166   Human T-cell leukemia virus 1 infection lve05167   Kaposi sarcoma-associated herpesvirus infection lve05170   Human immunodeficiency virus 1 infection lve05171   Coronavirus disease - COVID-19 lve05200   Pathways in cancer lve05203   Viral carcinogenesis lve05205   Proteoglycans in cancer lve05206   MicroRNAs in cancer lve05210   Colorectal cancer lve05211   Renal cell carcinoma lve05212   Pancreatic cancer lve05213   Endometrial cancer lve05214   Glioma lve05215   Prostate cancer lve05216   Thyroid cancer lve05218   Melanoma lve05219   Bladder cancer lve05220   Chronic myeloid leukemia lve05221   Acute myeloid leukemia lve05223   Non-small cell lung cancer lve05224   Breast cancer lve05225   Hepatocellular carcinoma lve05226   Gastric cancer lve05230   Central carbon metabolism in cancer lve05231   Choline metabolism in cancer lve05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:lve00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103070260 (MAPK1)    04012 ErbB signaling pathway     103070260 (MAPK1)    04014 Ras signaling pathway     103070260 (MAPK1)    04015 Rap1 signaling pathway     103070260 (MAPK1)    04350 TGF-beta signaling pathway     103070260 (MAPK1)    04370 VEGF signaling pathway     103070260 (MAPK1)    04371 Apelin signaling pathway     103070260 (MAPK1)    04668 TNF signaling pathway     103070260 (MAPK1)    04066 HIF-1 signaling pathway     103070260 (MAPK1)    04068 FoxO signaling pathway     103070260 (MAPK1)    04072 Phospholipase D signaling pathway     103070260 (MAPK1)    04071 Sphingolipid signaling pathway     103070260 (MAPK1)    04024 cAMP signaling pathway     103070260 (MAPK1)    04022 cGMP-PKG signaling pathway     103070260 (MAPK1)    04151 PI3K-Akt signaling pathway     103070260 (MAPK1)    04150 mTOR signaling pathway     103070260 (MAPK1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     103070260 (MAPK1)   09143 Cell growth and death    04114 Oocyte meiosis     103070260 (MAPK1)    04210 Apoptosis     103070260 (MAPK1)    04218 Cellular senescence     103070260 (MAPK1)   09144 Cellular community - eukaryotes    04510 Focal adhesion     103070260 (MAPK1)    04520 Adherens junction     103070260 (MAPK1)    04540 Gap junction     103070260 (MAPK1)    04550 Signaling pathways regulating pluripotency of stem cells     103070260 (MAPK1)   09142 Cell motility    04810 Regulation of actin cytoskeleton     103070260 (MAPK1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103070260 (MAPK1)    04620 Toll-like receptor signaling pathway     103070260 (MAPK1)    04621 NOD-like receptor signaling pathway     103070260 (MAPK1)    04625 C-type lectin receptor signaling pathway     103070260 (MAPK1)    04650 Natural killer cell mediated cytotoxicity     103070260 (MAPK1)    04660 T cell receptor signaling pathway     103070260 (MAPK1)    04658 Th1 and Th2 cell differentiation     103070260 (MAPK1)    04659 Th17 cell differentiation     103070260 (MAPK1)    04657 IL-17 signaling pathway     103070260 (MAPK1)    04662 B cell receptor signaling pathway     103070260 (MAPK1)    04664 Fc epsilon RI signaling pathway     103070260 (MAPK1)    04666 Fc gamma R-mediated phagocytosis     103070260 (MAPK1)    04062 Chemokine signaling pathway     103070260 (MAPK1)   09152 Endocrine system    04910 Insulin signaling pathway     103070260 (MAPK1)    04929 GnRH secretion     103070260 (MAPK1)    04912 GnRH signaling pathway     103070260 (MAPK1)    04915 Estrogen signaling pathway     103070260 (MAPK1)    04914 Progesterone-mediated oocyte maturation     103070260 (MAPK1)    04917 Prolactin signaling pathway     103070260 (MAPK1)    04921 Oxytocin signaling pathway     103070260 (MAPK1)    04926 Relaxin signaling pathway     103070260 (MAPK1)    04935 Growth hormone synthesis, secretion and action     103070260 (MAPK1)    04919 Thyroid hormone signaling pathway     103070260 (MAPK1)    04928 Parathyroid hormone synthesis, secretion and action     103070260 (MAPK1)    04916 Melanogenesis     103070260 (MAPK1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     103070260 (MAPK1)    04270 Vascular smooth muscle contraction     103070260 (MAPK1)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     103070260 (MAPK1)   09156 Nervous system    04724 Glutamatergic synapse     103070260 (MAPK1)    04725 Cholinergic synapse     103070260 (MAPK1)    04726 Serotonergic synapse     103070260 (MAPK1)    04720 Long-term potentiation     103070260 (MAPK1)    04730 Long-term depression     103070260 (MAPK1)    04723 Retrograde endocannabinoid signaling     103070260 (MAPK1)    04722 Neurotrophin signaling pathway     103070260 (MAPK1)   09158 Development and regeneration    04360 Axon guidance     103070260 (MAPK1)    04380 Osteoclast differentiation     103070260 (MAPK1)   09159 Environmental adaptation    04713 Circadian entrainment     103070260 (MAPK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103070260 (MAPK1)    05206 MicroRNAs in cancer     103070260 (MAPK1)    05205 Proteoglycans in cancer     103070260 (MAPK1)    05203 Viral carcinogenesis     103070260 (MAPK1)    05230 Central carbon metabolism in cancer     103070260 (MAPK1)    05231 Choline metabolism in cancer     103070260 (MAPK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     103070260 (MAPK1)   09162 Cancer: specific types    05210 Colorectal cancer     103070260 (MAPK1)    05212 Pancreatic cancer     103070260 (MAPK1)    05225 Hepatocellular carcinoma     103070260 (MAPK1)    05226 Gastric cancer     103070260 (MAPK1)    05214 Glioma     103070260 (MAPK1)    05216 Thyroid cancer     103070260 (MAPK1)    05221 Acute myeloid leukemia     103070260 (MAPK1)    05220 Chronic myeloid leukemia     103070260 (MAPK1)    05218 Melanoma     103070260 (MAPK1)    05211 Renal cell carcinoma     103070260 (MAPK1)    05219 Bladder cancer     103070260 (MAPK1)    05215 Prostate cancer     103070260 (MAPK1)    05213 Endometrial cancer     103070260 (MAPK1)    05224 Breast cancer     103070260 (MAPK1)    05223 Non-small cell lung cancer     103070260 (MAPK1)   09164 Neurodegenerative disease    05010 Alzheimer disease     103070260 (MAPK1)    05020 Prion disease     103070260 (MAPK1)    05022 Pathways of neurodegeneration - multiple diseases     103070260 (MAPK1)   09165 Substance dependence    05034 Alcoholism     103070260 (MAPK1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     103070260 (MAPK1)    04933 AGE-RAGE signaling pathway in diabetic complications     103070260 (MAPK1)    04934 Cushing syndrome     103070260 (MAPK1)   09171 Infectious disease: bacterial    05132 Salmonella infection     103070260 (MAPK1)    05135 Yersinia infection     103070260 (MAPK1)    05133 Pertussis     103070260 (MAPK1)    05152 Tuberculosis     103070260 (MAPK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103070260 (MAPK1)    05170 Human immunodeficiency virus 1 infection     103070260 (MAPK1)    05161 Hepatitis B     103070260 (MAPK1)    05160 Hepatitis C     103070260 (MAPK1)    05171 Coronavirus disease - COVID-19     103070260 (MAPK1)    05164 Influenza A     103070260 (MAPK1)    05163 Human cytomegalovirus infection     103070260 (MAPK1)    05167 Kaposi sarcoma-associated herpesvirus infection     103070260 (MAPK1)    05165 Human papillomavirus infection     103070260 (MAPK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     103070260 (MAPK1)    05140 Leishmaniasis     103070260 (MAPK1)    05142 Chagas disease     103070260 (MAPK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     103070260 (MAPK1)    01524 Platinum drug resistance     103070260 (MAPK1)    01522 Endocrine resistance     103070260 (MAPK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:lve01001]     103070260 (MAPK1)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:lve03036]     103070260 (MAPK1)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:lve04147]     103070260 (MAPK1) Enzymes [BR:lve01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.24  mitogen-activated protein kinase      103070260 (MAPK1) Protein kinases [BR:lve01001]  Serine/threonine kinases: CMGC group   MAPK family [OT]    103070260 (MAPK1) Chromosome and associated proteins [BR:lve03036]  Eukaryotic type   Centromeric chromatin formation proteins    SAC (spindle assembly checkpoint) factors     Protein kinases      103070260 (MAPK1) Exosome [BR:lve04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    103070260 (MAPK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr APH Choline_kinase FTA2 Kdo Kinase-like Motif Other DBs NCBI-GeneID:  103070260 NCBI-ProteinID:  XP_007451077 UniProt:  A0A340WNH5 LinkDB All DBs Position Un AA seq 263 aa AA seqDB search MKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLL NTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCI LAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNR LFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDD LPKEKLKELIFEETARFQPGYRS NT seq 792 nt NT seq  +upstreamnt  +downstreamnt atgaaagatgtatatatagtacaggacctcatggaaacagatctctacaagctcttgaag acgcaacacctcagcaatgaccatatctgctattttctttaccagatcctcagagggtta aaatatatccattcagctaacgtgctgcaccgtgacctcaaaccttccaacctgctgctc aacaccacctgcgatctcaagatctgtgactttggcttggcccgtgttgcagatccagac catgatcacacagggttcctgacggagtacgttgccacacgttggtacagggctccggaa attatgttgaattccaagggctacaccaagtccattgatatttggtctgtaggctgcatc ctggcagagatgctctccaacaggcccatcttcccggggaagcattacctcgaccagctg aaccacattctgggtattcttggatccccatcccaggaagacctgaattgtataataaat ttaaaagctagaaactatttgctttctcttccgcacaaaaataaggtgccatggaacagg ctgttcccaaatgctgactccaaagctctagatttactggacaagatgttgacgttcaac cctcataagaggattgaggtggaacaggctctggcccacccatacctggagcagtactac gacccaagtgacgagcccatcgccgaagcaccgttcaagtttgacatggaattggatgac ttgcccaaggaaaagctcaaagaactcatttttgaagagaccgctagattccagccagga tacagatcttaa

Lipotes vexillifer (Yangtze River dolphin): 103075543 Help Entry 103075543         CDS       T03090                                  Gene name MAPK3 Definition (RefSeq) mitogen-activated protein kinase 3   KO K04371   mitogen-activated protein kinase 1/3 [EC:2.7.11.24] Organism lve  Lipotes vexillifer (Yangtze River dolphin) Pathway lve01521   EGFR tyrosine kinase inhibitor resistance lve01522   Endocrine resistance lve01524   Platinum drug resistance lve04010   MAPK signaling pathway lve04012   ErbB signaling pathway lve04014   Ras signaling pathway lve04015   Rap1 signaling pathway lve04022   cGMP-PKG signaling pathway lve04024   cAMP signaling pathway lve04062   Chemokine signaling pathway lve04066   HIF-1 signaling pathway lve04068   FoxO signaling pathway lve04071   Sphingolipid signaling pathway lve04072   Phospholipase D signaling pathway lve04114   Oocyte meiosis lve04140   Autophagy - animal lve04150   mTOR signaling pathway lve04151   PI3K-Akt signaling pathway lve04210   Apoptosis lve04218   Cellular senescence lve04261   Adrenergic signaling in cardiomyocytes lve04270   Vascular smooth muscle contraction lve04350   TGF-beta signaling pathway lve04360   Axon guidance lve04370   VEGF signaling pathway lve04371   Apelin signaling pathway lve04380   Osteoclast differentiation lve04510   Focal adhesion lve04520   Adherens junction lve04540   Gap junction lve04550   Signaling pathways regulating pluripotency of stem cells lve04611   Platelet activation lve04620   Toll-like receptor signaling pathway lve04621   NOD-like receptor signaling pathway lve04625   C-type lectin receptor signaling pathway lve04650   Natural killer cell mediated cytotoxicity lve04657   IL-17 signaling pathway lve04658   Th1 and Th2 cell differentiation lve04659   Th17 cell differentiation lve04660   T cell receptor signaling pathway lve04662   B cell receptor signaling pathway lve04664   Fc epsilon RI signaling pathway lve04666   Fc gamma R-mediated phagocytosis lve04668   TNF signaling pathway lve04713   Circadian entrainment lve04720   Long-term potentiation lve04722   Neurotrophin signaling pathway lve04723   Retrograde endocannabinoid signaling lve04724   Glutamatergic synapse lve04725   Cholinergic synapse lve04726   Serotonergic synapse lve04730   Long-term depression lve04810   Regulation of actin cytoskeleton lve04910   Insulin signaling pathway lve04912   GnRH signaling pathway lve04914   Progesterone-mediated oocyte maturation lve04915   Estrogen signaling pathway lve04916   Melanogenesis lve04917   Prolactin signaling pathway lve04919   Thyroid hormone signaling pathway lve04921   Oxytocin signaling pathway lve04926   Relaxin signaling pathway lve04928   Parathyroid hormone synthesis, secretion and action lve04929   GnRH secretion lve04930   Type II diabetes mellitus lve04933   AGE-RAGE signaling pathway in diabetic complications lve04934   Cushing syndrome lve04935   Growth hormone synthesis, secretion and action lve04960   Aldosterone-regulated sodium reabsorption lve05010   Alzheimer disease lve05020   Prion disease lve05022   Pathways of neurodegeneration - multiple diseases lve05034   Alcoholism lve05132   Salmonella infection lve05133   Pertussis lve05135   Yersinia infection lve05140   Leishmaniasis lve05142   Chagas disease lve05145   Toxoplasmosis lve05152   Tuberculosis lve05160   Hepatitis C lve05161   Hepatitis B lve05163   Human cytomegalovirus infection lve05164   Influenza A lve05165   Human papillomavirus infection lve05166   Human T-cell leukemia virus 1 infection lve05167   Kaposi sarcoma-associated herpesvirus infection lve05170   Human immunodeficiency virus 1 infection lve05171   Coronavirus disease - COVID-19 lve05200   Pathways in cancer lve05203   Viral carcinogenesis lve05205   Proteoglycans in cancer lve05206   MicroRNAs in cancer lve05210   Colorectal cancer lve05211   Renal cell carcinoma lve05212   Pancreatic cancer lve05213   Endometrial cancer lve05214   Glioma lve05215   Prostate cancer lve05216   Thyroid cancer lve05218   Melanoma lve05219   Bladder cancer lve05220   Chronic myeloid leukemia lve05221   Acute myeloid leukemia lve05223   Non-small cell lung cancer lve05224   Breast cancer lve05225   Hepatocellular carcinoma lve05226   Gastric cancer lve05230   Central carbon metabolism in cancer lve05231   Choline metabolism in cancer lve05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:lve00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103075543 (MAPK3)    04012 ErbB signaling pathway     103075543 (MAPK3)    04014 Ras signaling pathway     103075543 (MAPK3)    04015 Rap1 signaling pathway     103075543 (MAPK3)    04350 TGF-beta signaling pathway     103075543 (MAPK3)    04370 VEGF signaling pathway     103075543 (MAPK3)    04371 Apelin signaling pathway     103075543 (MAPK3)    04668 TNF signaling pathway     103075543 (MAPK3)    04066 HIF-1 signaling pathway     103075543 (MAPK3)    04068 FoxO signaling pathway     103075543 (MAPK3)    04072 Phospholipase D signaling pathway     103075543 (MAPK3)    04071 Sphingolipid signaling pathway     103075543 (MAPK3)    04024 cAMP signaling pathway     103075543 (MAPK3)    04022 cGMP-PKG signaling pathway     103075543 (MAPK3)    04151 PI3K-Akt signaling pathway     103075543 (MAPK3)    04150 mTOR signaling pathway     103075543 (MAPK3)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     103075543 (MAPK3)   09143 Cell growth and death    04114 Oocyte meiosis     103075543 (MAPK3)    04210 Apoptosis     103075543 (MAPK3)    04218 Cellular senescence     103075543 (MAPK3)   09144 Cellular community - eukaryotes    04510 Focal adhesion     103075543 (MAPK3)    04520 Adherens junction     103075543 (MAPK3)    04540 Gap junction     103075543 (MAPK3)    04550 Signaling pathways regulating pluripotency of stem cells     103075543 (MAPK3)   09142 Cell motility    04810 Regulation of actin cytoskeleton     103075543 (MAPK3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103075543 (MAPK3)    04620 Toll-like receptor signaling pathway     103075543 (MAPK3)    04621 NOD-like receptor signaling pathway     103075543 (MAPK3)    04625 C-type lectin receptor signaling pathway     103075543 (MAPK3)    04650 Natural killer cell mediated cytotoxicity     103075543 (MAPK3)    04660 T cell receptor signaling pathway     103075543 (MAPK3)    04658 Th1 and Th2 cell differentiation     103075543 (MAPK3)    04659 Th17 cell differentiation     103075543 (MAPK3)    04657 IL-17 signaling pathway     103075543 (MAPK3)    04662 B cell receptor signaling pathway     103075543 (MAPK3)    04664 Fc epsilon RI signaling pathway     103075543 (MAPK3)    04666 Fc gamma R-mediated phagocytosis     103075543 (MAPK3)    04062 Chemokine signaling pathway     103075543 (MAPK3)   09152 Endocrine system    04910 Insulin signaling pathway     103075543 (MAPK3)    04929 GnRH secretion     103075543 (MAPK3)    04912 GnRH signaling pathway     103075543 (MAPK3)    04915 Estrogen signaling pathway     103075543 (MAPK3)    04914 Progesterone-mediated oocyte maturation     103075543 (MAPK3)    04917 Prolactin signaling pathway     103075543 (MAPK3)    04921 Oxytocin signaling pathway     103075543 (MAPK3)    04926 Relaxin signaling pathway     103075543 (MAPK3)    04935 Growth hormone synthesis, secretion and action     103075543 (MAPK3)    04919 Thyroid hormone signaling pathway     103075543 (MAPK3)    04928 Parathyroid hormone synthesis, secretion and action     103075543 (MAPK3)    04916 Melanogenesis     103075543 (MAPK3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     103075543 (MAPK3)    04270 Vascular smooth muscle contraction     103075543 (MAPK3)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     103075543 (MAPK3)   09156 Nervous system    04724 Glutamatergic synapse     103075543 (MAPK3)    04725 Cholinergic synapse     103075543 (MAPK3)    04726 Serotonergic synapse     103075543 (MAPK3)    04720 Long-term potentiation     103075543 (MAPK3)    04730 Long-term depression     103075543 (MAPK3)    04723 Retrograde endocannabinoid signaling     103075543 (MAPK3)    04722 Neurotrophin signaling pathway     103075543 (MAPK3)   09158 Development and regeneration    04360 Axon guidance     103075543 (MAPK3)    04380 Osteoclast differentiation     103075543 (MAPK3)   09159 Environmental adaptation    04713 Circadian entrainment     103075543 (MAPK3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103075543 (MAPK3)    05206 MicroRNAs in cancer     103075543 (MAPK3)    05205 Proteoglycans in cancer     103075543 (MAPK3)    05203 Viral carcinogenesis     103075543 (MAPK3)    05230 Central carbon metabolism in cancer     103075543 (MAPK3)    05231 Choline metabolism in cancer     103075543 (MAPK3)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     103075543 (MAPK3)   09162 Cancer: specific types    05210 Colorectal cancer     103075543 (MAPK3)    05212 Pancreatic cancer     103075543 (MAPK3)    05225 Hepatocellular carcinoma     103075543 (MAPK3)    05226 Gastric cancer     103075543 (MAPK3)    05214 Glioma     103075543 (MAPK3)    05216 Thyroid cancer     103075543 (MAPK3)    05221 Acute myeloid leukemia     103075543 (MAPK3)    05220 Chronic myeloid leukemia     103075543 (MAPK3)    05218 Melanoma     103075543 (MAPK3)    05211 Renal cell carcinoma     103075543 (MAPK3)    05219 Bladder cancer     103075543 (MAPK3)    05215 Prostate cancer     103075543 (MAPK3)    05213 Endometrial cancer     103075543 (MAPK3)    05224 Breast cancer     103075543 (MAPK3)    05223 Non-small cell lung cancer     103075543 (MAPK3)   09164 Neurodegenerative disease    05010 Alzheimer disease     103075543 (MAPK3)    05020 Prion disease     103075543 (MAPK3)    05022 Pathways of neurodegeneration - multiple diseases     103075543 (MAPK3)   09165 Substance dependence    05034 Alcoholism     103075543 (MAPK3)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     103075543 (MAPK3)    04933 AGE-RAGE signaling pathway in diabetic complications     103075543 (MAPK3)    04934 Cushing syndrome     103075543 (MAPK3)   09171 Infectious disease: bacterial    05132 Salmonella infection     103075543 (MAPK3)    05135 Yersinia infection     103075543 (MAPK3)    05133 Pertussis     103075543 (MAPK3)    05152 Tuberculosis     103075543 (MAPK3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103075543 (MAPK3)    05170 Human immunodeficiency virus 1 infection     103075543 (MAPK3)    05161 Hepatitis B     103075543 (MAPK3)    05160 Hepatitis C     103075543 (MAPK3)    05171 Coronavirus disease - COVID-19     103075543 (MAPK3)    05164 Influenza A     103075543 (MAPK3)    05163 Human cytomegalovirus infection     103075543 (MAPK3)    05167 Kaposi sarcoma-associated herpesvirus infection     103075543 (MAPK3)    05165 Human papillomavirus infection     103075543 (MAPK3)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     103075543 (MAPK3)    05140 Leishmaniasis     103075543 (MAPK3)    05142 Chagas disease     103075543 (MAPK3)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     103075543 (MAPK3)    01524 Platinum drug resistance     103075543 (MAPK3)    01522 Endocrine resistance     103075543 (MAPK3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:lve01001]     103075543 (MAPK3)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:lve03036]     103075543 (MAPK3)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:lve04147]     103075543 (MAPK3) Enzymes [BR:lve01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.24  mitogen-activated protein kinase      103075543 (MAPK3) Protein kinases [BR:lve01001]  Serine/threonine kinases: CMGC group   MAPK family [OT]    103075543 (MAPK3) Chromosome and associated proteins [BR:lve03036]  Eukaryotic type   Centromeric chromatin formation proteins    SAC (spindle assembly checkpoint) factors     Protein kinases      103075543 (MAPK3) Exosome [BR:lve04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    103075543 (MAPK3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr APH Choline_kinase FTA2 Kdo NDUF_B4 Pkinase_fungal Motif Other DBs NCBI-GeneID:  103075543 NCBI-ProteinID:  XP_007452842 UniProt:  A0A340WYU9 LinkDB All DBs Position Un AA seq 325 aa AA seqDB search MVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEA MRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLI NTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCI LAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAK LFPKSDPKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFDMELDD LPKERLKELIFQETARFQPGVLEAP NT seq 978 nt NT seq  +upstreamnt  +downstreamnt atggtcagctcagcttacgaccatgtgcgcaagactcgagtggccatcaagaaaatcagc ccctttgagcatcagacctactgccagcgtacgttgcgagagatccagatcttgctgcgc ttccgccatgagaacgtcatcggcatccgagacattctgcgggcacccaccctggaagcc atgagggatgtctacattgtgcaagacctgatggagacagacctgtacaagttgcttaaa agccagcagctgagcaacgaccacatctgctacttcctctaccaaatcctgcggggcctc aagtatatccattctgccaacgtgctccaccgggatttaaagccctccaacctgctcatc aacaccacctgcgaccttaagatctgtgattttggtcttgcccggattgccgatcctgag cacgaccacactggctttctgacggaatacgtggccacacgctggtaccgggccccagag atcatgcttaactccaagggctacaccaagtccatcgacatctggtctgtgggctgcatt ctggctgagatgctctccaaccggcccatcttcccgggcaagcactacctggaccagctc aaccacattctgggtatcctgggctccccctcccaggaggacctgaattgtatcatcaac atgaaggcccgaaactacctacagtctctaccctccaagaccaaggtggcctgggccaag ctttttcccaagtcggaccccaaagctcttgacctgctggaccggatgttgacctttaac cccaacaaacggatcacagtggaagaagcactggctcacccctacctggaacagtactac gacccaacagatgagccagtggccgaggaacctttcaccttcgacatggagctggatgat ctacccaaggagcggctgaaggagctcatcttccaggagacagcccgtttccagcctggg gtgctggaggccccctaa

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