Lipotes vexillifer (Yangtze River dolphin): 103070451 Help Entry 103070451         CDS       T03090                                  Gene name ADCY9 Definition (RefSeq) adenylate cyclase 9   KO K08049   adenylate cyclase 9 [EC:4.6.1.1] Organism lve  Lipotes vexillifer (Yangtze River dolphin) Pathway lve00230   Purine metabolism lve01100   Metabolic pathways lve01522   Endocrine resistance lve04015   Rap1 signaling pathway lve04020   Calcium signaling pathway lve04022   cGMP-PKG signaling pathway lve04024   cAMP signaling pathway lve04062   Chemokine signaling pathway lve04072   Phospholipase D signaling pathway lve04114   Oocyte meiosis lve04211   Longevity regulating pathway lve04213   Longevity regulating pathway - multiple species lve04261   Adrenergic signaling in cardiomyocytes lve04270   Vascular smooth muscle contraction lve04371   Apelin signaling pathway lve04540   Gap junction lve04611   Platelet activation lve04713   Circadian entrainment lve04714   Thermogenesis lve04723   Retrograde endocannabinoid signaling lve04724   Glutamatergic synapse lve04725   Cholinergic synapse lve04727   GABAergic synapse lve04750   Inflammatory mediator regulation of TRP channels lve04911   Insulin secretion lve04912   GnRH signaling pathway lve04913   Ovarian steroidogenesis lve04914   Progesterone-mediated oocyte maturation lve04915   Estrogen signaling pathway lve04916   Melanogenesis lve04918   Thyroid hormone synthesis lve04921   Oxytocin signaling pathway lve04923   Regulation of lipolysis in adipocytes lve04925   Aldosterone synthesis and secretion lve04926   Relaxin signaling pathway lve04927   Cortisol synthesis and secretion lve04928   Parathyroid hormone synthesis, secretion and action lve04934   Cushing syndrome lve04935   Growth hormone synthesis, secretion and action lve04961   Endocrine and other factor-regulated calcium reabsorption lve04962   Vasopressin-regulated water reabsorption lve04970   Salivary secretion lve04971   Gastric acid secretion lve04972   Pancreatic secretion lve04976   Bile secretion lve05032   Morphine addiction lve05163   Human cytomegalovirus infection lve05166   Human T-cell leukemia virus 1 infection lve05200   Pathways in cancer lve05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lve00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     103070451 (ADCY9)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103070451 (ADCY9)    04371 Apelin signaling pathway     103070451 (ADCY9)    04020 Calcium signaling pathway     103070451 (ADCY9)    04072 Phospholipase D signaling pathway     103070451 (ADCY9)    04024 cAMP signaling pathway     103070451 (ADCY9)    04022 cGMP-PKG signaling pathway     103070451 (ADCY9)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     103070451 (ADCY9)   09144 Cellular community - eukaryotes    04540 Gap junction     103070451 (ADCY9)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103070451 (ADCY9)    04062 Chemokine signaling pathway     103070451 (ADCY9)   09152 Endocrine system    04911 Insulin secretion     103070451 (ADCY9)    04923 Regulation of lipolysis in adipocytes     103070451 (ADCY9)    04912 GnRH signaling pathway     103070451 (ADCY9)    04913 Ovarian steroidogenesis     103070451 (ADCY9)    04915 Estrogen signaling pathway     103070451 (ADCY9)    04914 Progesterone-mediated oocyte maturation     103070451 (ADCY9)    04921 Oxytocin signaling pathway     103070451 (ADCY9)    04926 Relaxin signaling pathway     103070451 (ADCY9)    04935 Growth hormone synthesis, secretion and action     103070451 (ADCY9)    04918 Thyroid hormone synthesis     103070451 (ADCY9)    04928 Parathyroid hormone synthesis, secretion and action     103070451 (ADCY9)    04916 Melanogenesis     103070451 (ADCY9)    04925 Aldosterone synthesis and secretion     103070451 (ADCY9)    04927 Cortisol synthesis and secretion     103070451 (ADCY9)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     103070451 (ADCY9)    04270 Vascular smooth muscle contraction     103070451 (ADCY9)   09154 Digestive system    04970 Salivary secretion     103070451 (ADCY9)    04971 Gastric acid secretion     103070451 (ADCY9)    04972 Pancreatic secretion     103070451 (ADCY9)    04976 Bile secretion     103070451 (ADCY9)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     103070451 (ADCY9)    04961 Endocrine and other factor-regulated calcium reabsorption     103070451 (ADCY9)   09156 Nervous system    04724 Glutamatergic synapse     103070451 (ADCY9)    04727 GABAergic synapse     103070451 (ADCY9)    04725 Cholinergic synapse     103070451 (ADCY9)    04723 Retrograde endocannabinoid signaling     103070451 (ADCY9)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     103070451 (ADCY9)   09149 Aging    04211 Longevity regulating pathway     103070451 (ADCY9)    04213 Longevity regulating pathway - multiple species     103070451 (ADCY9)   09159 Environmental adaptation    04713 Circadian entrainment     103070451 (ADCY9)    04714 Thermogenesis     103070451 (ADCY9)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103070451 (ADCY9)   09165 Substance dependence    05032 Morphine addiction     103070451 (ADCY9)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     103070451 (ADCY9)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     103070451 (ADCY9)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103070451 (ADCY9)    05163 Human cytomegalovirus infection     103070451 (ADCY9)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     103070451 (ADCY9) Enzymes [BR:lve01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      103070451 (ADCY9) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc DUF512 DUF1053 AC_N Motif Other DBs NCBI-GeneID:  103070451 NCBI-ProteinID:  XP_007453542 UniProt:  A0A340X0V2 LinkDB All DBs Position Un AA seq 1353 aa AA seqDB search MASPPHQQLLQHHSTEVSCDSSGDSNSVRVKINPKQLSSNSHPKHCKYSISSSCSSSGDS GGVPRRMGAGGRLRRKKKLPQLFERASSRWWDPKFDSMNLEEACMERCFPQTQRRFRYAL FYIGFACLLWSIYFGVHMRSKLTVMVAPALCFLVVCVGIFLFTFTKLYARHYVWTSLVLT LLVFALTLASQFQVLTPFSGRVDSFNHTRAARPTDTCLSQVGSFSMCIEVLFLLYTVMHL PLYLSLILGVAYSVLFETFGYHFQDKACFPSPEAEALHWELLSRALLHVCIHAIGIHLFI MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKR HATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIRAIEQFCQEK KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD DRYEMEDGKVTERLGQNVVADQLKGLKTYLIAGQRAKESHCSCSEALLSGFEVIDGSRVS SGPRGQGTASPGSVSDLAQTVKTFDNLKTCPSCRIMFAPKLEAGAEGGAVQNGCQEEPKK STKASGGPSSKTQNGLLSPPPEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNI REKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELEQAYRTSYQEEVIKNSPVKTF ASATFSSLLDVFLSTTVFLILSITCFLKYGAASMPPPPAALVVFGAALLLEVLSLVVSVR MVFFLEDVMACTKRLLEWIAGWLPRHFIGAILVSLPALAVYSHVTSEFETNIHSTVFTGS AVLITVVHYCNFCQLSSWMRSSLATVVGAGPLLLLYVSLCPDSSIVISHLDAVQNFSSER NPCNASLPHDSRSPASLIGQEVILVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTK IQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDNGGVIFASIVNFSEFYEENYEGGKE CYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNATQCRDGSHPQEHLQILFE FAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTT GVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCTDNGMVPQHQLSISP DIRVQVDGSIGRSPTDEITNLVPSVQNPDQVSLGSENNTQARDTHPSSKKPWKEPIKAEE RCRFSKAIEKSDCEEAGEEEANELTKLNVSKRA NT seq 4062 nt NT seq  +upstreamnt  +downstreamnt atggcttccccgccccaccagcagctgctgcagcaccacagcaccgaggtgagttgtgac tccagcggagacagcaacagcgtgagggtcaaaatcaaccccaagcagctgtcctccaac agccacccgaaacactgcaagtacagcatctcctccagctgtagcagctccggggactca gggggcgtcccccggagaatgggcgccggaggccgcctgcgcaggaaaaagaagctgcct cagctgttcgagagggcctccagccggtggtgggaccccaaattcgactccatgaacctg gaggaggcttgcatggagcgctgcttcccgcagacccagcgccgcttccggtatgcgctc ttctacattggcttcgcctgccttctctggagcatctattttggggtccacatgagatcc aaactgactgtcatggtagcccctgctctgtgcttcctcgtggtgtgtgtgggcattttt ctgtttaccttcaccaagctgtacgcccggcattacgtgtggacctcgctggttcttacc ctcctggtgttcgccctgactctggcttcccagtttcaggttttgacgcccttctcagga cgagttgacagcttcaatcatactcgggcagccaggcccacagacacttgcttatctcaa gtggggagcttttccatgtgcattgaagtgctctttttgctctacaccgtcatgcactta cctttgtacttgagcttgattttgggagtggcctattctgttctttttgagacctttggc tatcatttccaagacaaagcctgcttcccctcacctgaagcagaggccctgcactgggag ctgctgagccgagccctgctccacgtctgcattcacgccattgggatccacctgttcatc atgtcccaggtgagatccaggagcaccttcctcaaggtgggccagtcaattatgcatgga aaggatctggaagtggaaaaagccctgaaagagaggatgattcattctgtgatgccaaga atcatagctgatgacttgatgaagcagggggacgaggagagcgagaattctgtcaaaagg catgccacctccagccccaagaacaggaagaaaaagtcttccatacagaaagcccctatt gccttccgcccgtttaaaatgcagcagatcgaagaagtcagtattttatttgcagatatc gtgggcttcaccaagatgagtgccaataagtccgcccatgccctggtggggctcctcaac gatctgttcggccgcttcgaccggttgtgcgaggagaccaagtgtgagaaaatcagcact ctgggagactgctactactgtgtggccgggtgtcccgagcctcgggccgaccatgcctac tgctgcatcgaaatgggcttgggcatgataagggctatcgagcagttctgccaagagaag aaagagatggtgaacatgcgtgttggggttcacacggggactgtcttgtgcggcatcttg ggcatgaggaggtttaaattcgatgtgtggtccaatgatgtgaacttggccaatctcatg gagcagctgggagtggctggcaaggttcacatttccgaggccaccgcaaaatacctagat gaccggtacgaaatggaagatgggaaggtaactgaacgcctcggccagaacgttgttgct gaccagttgaaaggtttgaagacatacctgatagcgggtcagagagcgaaggagtctcat tgcagctgttcagaggccttgctttctggctttgaggtcattgacggctcacgggtgtcc tcaggccctaggggacaggggacagcatcgccagggagtgtcagtgacttggcgcagact gtcaaaacctttgataaccttaagacctgcccatcgtgcagaatcatgtttgctcccaaa ttggaagctggcgctgaaggcggagcagtccagaatggctgtcaggaggagcccaagaag agcaccaaggcttctggaggacccagttccaaaacgcaaaacggactgctgagccctccc ccggaggagaagctcaccaacagtcagacctccctgtgcgagatcttacaagagaaggga aggtgggcaggtgtgagcttggaccagtcagccctccttccgctgaggttcaagaacatc cgggagaaaacggatgcccattttgttgatgttatcaaggaagacagcctgatgaaagat tatttttttaagccacccattaatcagttcagcttgaacttcctggatcaggagctagaa caagcctacaggaccagctatcaagaagaggttataaagaattctcccgtgaagactttt gccagtgccaccttcagctccctcctggatgtgtttctgtcgacaacagtgtttctgatt ctctccattacctgcttcctgaagtatggggctgcctccatgccacccccgccggccgcc ctggtggtcttcggagcagccctgcttctggaggtcctgtccctcgtggtctccgtcagg atggtgttcttcctggaggatgtgatggcttgtaccaagcgcctgctggagtggatagcc ggctggctcccgcgccatttcatcggggccatcctggtgtccctccccgccctcgcggtc tattcacatgtcacctccgaatttgagacaaacatacactccaccgtgttcacgggctcg gctgtcctgatcaccgtggtgcactactgtaacttctgccagctcagctcctggatgagg tcctccttggccacagtcgtcggggccgggcccctgctgctgctctacgtctccctctgc ccagacagttccatagtaatttcgcacctggatgcagtacagaatttcagctccgagagg aatccgtgcaacgcctcgctgccgcacgacagcaggagcccagccagcctaatcggccag gaggtgattcttgtcttcttcctcctgctcttgttggtctggttcctgaatcgagaattc gaagtcagctaccgcctacactaccacggggacgtggaggcggacctgcaccgcactaag atccagagcatgagggaccaggccgactggctgctgagaaacatcatcccctaccacgtg gccgagcagctgaaggtctcccagacctactccaagaaccacgacaacggaggagtcatc tttgccagcatcgtcaacttcagcgagttctatgaggagaactacgagggcggcaaggag tgctaccgggtcctcaacgagctgatcggggacttcgacgagctcctgagcaagccggac tacagcagcatcgagaagatcaagaccatcggggccacatacatggccgcgtctgggctg aatgccacacagtgccgtgacggcagccacccgcaggagcacctgcagatcctgtttgag tttgccaaggagatgatgcgtgtggtggacgacttcaacaataacatgctctggttcaac ttcaagctcagggtgggcttcaaccatgggccgctgacggcaggcgtcattggcaccacc aagctgctgtacgacatctggggagacacggtcaacatcgccagcaggatggacaccacg ggggtggagtgccgcatccaggtcagcgaggaaagctaccgcgtcctgagcaagatgggc tacgacttcgactacagagggacggtgaacgtcaagggcaaaggccagatgaagacctac ctgtaccccaagtgcacggacaacgggatggtgccgcagcaccagctctccatctcccct gacatccgagtccaggtggacggcagcatcggacgctcccccacggacgagatcaccaac ctggtgccttccgtacagaacccggaccaggtgtccctgggctccgagaacaacacacag gccagggacactcacccgtcttctaagaaaccctggaaggagcccatcaaagccgaagaa aggtgtaggttcagcaaagccatagagaaaagcgactgtgaagaagcaggggaggaggaa gccaatgaactcaccaagctcaacgtctcaaagagggcgtga

Lipotes vexillifer (Yangtze River dolphin): 103075153 Help Entry 103075153         CDS       T03090                                  Gene name ADCY6 Definition (RefSeq) adenylate cyclase 6   KO K08046   adenylate cyclase 6 [EC:4.6.1.1] Organism lve  Lipotes vexillifer (Yangtze River dolphin) Pathway lve00230   Purine metabolism lve01100   Metabolic pathways lve01522   Endocrine resistance lve04015   Rap1 signaling pathway lve04022   cGMP-PKG signaling pathway lve04024   cAMP signaling pathway lve04062   Chemokine signaling pathway lve04072   Phospholipase D signaling pathway lve04114   Oocyte meiosis lve04211   Longevity regulating pathway lve04213   Longevity regulating pathway - multiple species lve04261   Adrenergic signaling in cardiomyocytes lve04270   Vascular smooth muscle contraction lve04371   Apelin signaling pathway lve04540   Gap junction lve04611   Platelet activation lve04713   Circadian entrainment lve04714   Thermogenesis lve04723   Retrograde endocannabinoid signaling lve04724   Glutamatergic synapse lve04725   Cholinergic synapse lve04727   GABAergic synapse lve04742   Taste transduction lve04750   Inflammatory mediator regulation of TRP channels lve04911   Insulin secretion lve04912   GnRH signaling pathway lve04913   Ovarian steroidogenesis lve04914   Progesterone-mediated oocyte maturation lve04915   Estrogen signaling pathway lve04916   Melanogenesis lve04918   Thyroid hormone synthesis lve04921   Oxytocin signaling pathway lve04923   Regulation of lipolysis in adipocytes lve04924   Renin secretion lve04925   Aldosterone synthesis and secretion lve04926   Relaxin signaling pathway lve04927   Cortisol synthesis and secretion lve04928   Parathyroid hormone synthesis, secretion and action lve04934   Cushing syndrome lve04935   Growth hormone synthesis, secretion and action lve04961   Endocrine and other factor-regulated calcium reabsorption lve04962   Vasopressin-regulated water reabsorption lve04970   Salivary secretion lve04971   Gastric acid secretion lve04972   Pancreatic secretion lve04976   Bile secretion lve05032   Morphine addiction lve05163   Human cytomegalovirus infection lve05166   Human T-cell leukemia virus 1 infection lve05200   Pathways in cancer lve05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lve00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     103075153 (ADCY6)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103075153 (ADCY6)    04371 Apelin signaling pathway     103075153 (ADCY6)    04072 Phospholipase D signaling pathway     103075153 (ADCY6)    04024 cAMP signaling pathway     103075153 (ADCY6)    04022 cGMP-PKG signaling pathway     103075153 (ADCY6)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     103075153 (ADCY6)   09144 Cellular community - eukaryotes    04540 Gap junction     103075153 (ADCY6)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103075153 (ADCY6)    04062 Chemokine signaling pathway     103075153 (ADCY6)   09152 Endocrine system    04911 Insulin secretion     103075153 (ADCY6)    04923 Regulation of lipolysis in adipocytes     103075153 (ADCY6)    04912 GnRH signaling pathway     103075153 (ADCY6)    04913 Ovarian steroidogenesis     103075153 (ADCY6)    04915 Estrogen signaling pathway     103075153 (ADCY6)    04914 Progesterone-mediated oocyte maturation     103075153 (ADCY6)    04921 Oxytocin signaling pathway     103075153 (ADCY6)    04926 Relaxin signaling pathway     103075153 (ADCY6)    04935 Growth hormone synthesis, secretion and action     103075153 (ADCY6)    04918 Thyroid hormone synthesis     103075153 (ADCY6)    04928 Parathyroid hormone synthesis, secretion and action     103075153 (ADCY6)    04916 Melanogenesis     103075153 (ADCY6)    04924 Renin secretion     103075153 (ADCY6)    04925 Aldosterone synthesis and secretion     103075153 (ADCY6)    04927 Cortisol synthesis and secretion     103075153 (ADCY6)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     103075153 (ADCY6)    04270 Vascular smooth muscle contraction     103075153 (ADCY6)   09154 Digestive system    04970 Salivary secretion     103075153 (ADCY6)    04971 Gastric acid secretion     103075153 (ADCY6)    04972 Pancreatic secretion     103075153 (ADCY6)    04976 Bile secretion     103075153 (ADCY6)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     103075153 (ADCY6)    04961 Endocrine and other factor-regulated calcium reabsorption     103075153 (ADCY6)   09156 Nervous system    04724 Glutamatergic synapse     103075153 (ADCY6)    04727 GABAergic synapse     103075153 (ADCY6)    04725 Cholinergic synapse     103075153 (ADCY6)    04723 Retrograde endocannabinoid signaling     103075153 (ADCY6)   09157 Sensory system    04742 Taste transduction     103075153 (ADCY6)    04750 Inflammatory mediator regulation of TRP channels     103075153 (ADCY6)   09149 Aging    04211 Longevity regulating pathway     103075153 (ADCY6)    04213 Longevity regulating pathway - multiple species     103075153 (ADCY6)   09159 Environmental adaptation    04713 Circadian entrainment     103075153 (ADCY6)    04714 Thermogenesis     103075153 (ADCY6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103075153 (ADCY6)   09165 Substance dependence    05032 Morphine addiction     103075153 (ADCY6)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     103075153 (ADCY6)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     103075153 (ADCY6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103075153 (ADCY6)    05163 Human cytomegalovirus infection     103075153 (ADCY6)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     103075153 (ADCY6) Enzymes [BR:lve01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      103075153 (ADCY6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc DUF1053 HNOBA TBK1_ULD Motif Other DBs NCBI-GeneID:  103075153 NCBI-ProteinID:  XP_007452296 UniProt:  A0A340WTP8 LinkDB All DBs Position Un AA seq 1166 aa AA seqDB search MSWFSGLLVPKVDERKTAWGERNGQKRPRRGTRSSGFCTPRYMSCFQGAQPPSPTPAAAP RCPWQDEAFIRRGGPGKGLELGLRAVALGFEDPEATVAVGAAEGAPDAAARSRRACWRRL VQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLMAVLLAFHAAPAHPQPAYVA LLACAAVLFVALMVVCNRHSFRQDSMWLVSYVVLGILAAVQVGGALTASPRSPSVGLWCP VFFVYITYTLLPIRMRAAVFSGLGLSTLHLILAWQLNRGDAFLWKQLGANMLLFLCTNVI GICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKK EDMMFHRIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLR IKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHC GVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNAYL KEQHIETFLILGASQKRKEEKAMLAKLQRARANSMEGLMPRWVPDRTFSRTKDSKAFRQM GIDDSSKDNRGAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQREDLEKKYS RKVDPRFGAYVACALLVFCFICFIQLLVFPPSALMLGIYASIFLLLLVTVLTCAVYSCGS LFPQALRRLSRSIVRSRAHSTAVGIFSVLLVFISAIANMFTCNHTPIRTCAAQMLNLTPA DITACHLQQLNYSLGLDAPLCEGTAPTCSFPEYFVGSMLLSLLASSVFLHISSIGKLAMI FVLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASSNETFSGLDCSAAGRVALKYMTPVIL LVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLA RERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEE RFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNNFQ MKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQ LECRGVVKVKGKGEMTTYFLNGGPSS NT seq 3501 nt NT seq  +upstreamnt  +downstreamnt atgtcatggtttagtggcctcctggtccccaaagtggatgaacggaaaacagcctggggc gagcgcaatgggcagaagcgtccacgccgcgggactcgctccagtggcttctgcacaccc cgttatatgagctgctttcagggtgcacagccacccagcccgacccccgcagccgcgcct cggtgcccctggcaggatgaggccttcatccggaggggtggcccaggcaagggcctggag ctggggctgcgggctgtggccctgggcttcgaggaccctgaggcgaccgtggcagtcggg gccgctgagggggcccccgatgcagccgccaggagcaggcgagcttgctggcgccggctg gtgcaggtgttccagtcaaagcagttccgctcggccaagctggagcgcttgtaccagagg tactttttccagatgaaccagagcagcctgacgctgctgatggccgtgctggtgctgctc atggccgtgctgctggccttccacgcggcgcctgcccaccctcagcctgcctacgtggcc ctgctggcctgcgccgccgtcctcttcgtggcgctcatggtggtgtgcaatcgacacagc ttccgccaggactccatgtggctggtgagctacgtggtgctgggcatcctggcagccgtg caggtcggcggcgccctgacagccagcccccgcagcccttctgtaggcctctggtgcccc gtgttcttcgtctacatcacctacacgcttctccccatccgcatgcgggctgctgtcttc agtggcctgggcctctccaccctgcacttgatcttggcctggcaactcaaccgtggtgat gccttcctctggaagcagctcggtgccaacatgctgctgttcctctgcaccaatgtcatt ggcatctgcacacactacccagctgaggtgtctcagcgccaggcctttcaggagacccgt ggttacatccaggcccggctgcacctgcagcatgagaatcggcagcaggagcggctgctg ctgtccgtgttgccccagcatgttgccatggagatgaaagaagacatcaacacaaagaaa gaagacatgatgtttcacaggatctacatccagaagcatgacaatgtcagcatcctgttt gcggacattgaaggcttcaccagcctggcatcccagtgcacggcgcaggagctggtcatg accctgaacgagctctttgctcggtttgacaagctggctgcggaaaatcactgcctgagg atcaagatcttaggggactgttactattgtgtgtcagggctgccagaggcccgggcagac catgcccactgctgcgtggagatgggggtggacatgatcgaggccatctcgctggtgcgc gaggtgacaggtgtgaacgtgaacatgcgcgtgggcatccacagcgggcgcgtgcactgc ggcgtccttggcctgcggaaatggcagttcgatgtgtggtccaatgacgtgactctggcc aatcacatggaggccgggggccgggccggccgcatccacatcactcgggccacgctgcag tacctgaacggggactacgaggtggagccgggccgtggcggggagcgcaacgcctacctc aaggagcagcacattgagacgttcctcatcctgggagccagccagaaacggaaagaggag aaggccatgctggccaagctgcagcgggcgcgggccaactccatggaggggctgatgcca cgctgggtgcccgaccgcaccttctcccggaccaaggactcgaaggctttccggcagatg ggcattgatgattccagcaaggacaaccggggtgcccaggatgccctgaaccctgaggat gaggtagacgagttcctgggccgtgccatcgatgcccgcagcatcgatcagctgcgcaag gaccacgtgcgccggttcctgctcaccttccagagagaggatcttgaaaagaagtactcg cgaaaggtggacccccgcttcggagcctacgtggcctgtgccctgttggtcttctgcttc atctgcttcatccagctcctcgtcttcccaccctcagccctgatgcttgggatctatgcc agtatcttcctgctgttgctggtcaccgtgctgacctgcgccgtgtactcgtgtggctct ctgttccctcaggccctgcgacgtctgtctcgcagcatcgtccgctcgcgggcacatagc actgcggttggcatcttttccgtcctgcttgtgttcatctctgccatcgccaacatgttc acctgtaaccacacccccatacggacttgcgcagcccagatgctgaatttaacacctgct gacatcactgcctgccacctgcagcagctcaattactcactgggcctggatgctcccctg tgtgagggcaccgcccccacttgcagcttccctgagtacttcgtcgggagcatgctgctg agtctcttggccagctctgtcttcctgcacatcagtagcatcgggaagttggccatgatc tttgtcctggggctcatctatttggtgctgcttctgctggggcccccggccaccatcttt gacaactacgacctactgcttggcgtccatggcttggcttcttccaacgagaccttcagt gggctggactgctcagccgcagggagggtggcactcaaatatatgacccctgtgattctg ctggtgtttgcactggcgctgtatctgcatgcccagcaggtggaatcaactgcccgcctg gacttcctctggaaactgcaggccacaggggagaaggaggagatggaggagctccaggca tacaaccggcggctgctacataacattctgcccaaggacgtggccgcccacttccttgcc cgggagcgccggaatgatgagctctactatcagtcatgtgagtgcgtggccgtcatgttt gcctccattgccaacttctctgagttctacgtggagctagaggcaaacaatgagggtgtc gagtgcctgcggctgctcaacgagatcatcgctgacttcgatgagatcatcagcgaggag cggttccggcagctggagaagatcaagacgattggtagcacctacatggctgcctctggg ctgaatgccagcacctatgatcaggtgggccgctcccacatcactgcccttgccgactac gccatgcggctcatggagcagatgaagcacatcaatgagcactccttcaacaatttccag atgaagatcgggctgaacatgggcccagttgtggcaggcgtcattggggctcggaagccg cagtatgacatctgggggaacacagtgaatgtctctagccgcatggacagcacgggggtc cccgaccgaatccaggtgaccacggacctgtaccaggttctagcggccaagggctaccag ctggagtgtcgaggggtggtcaaggtgaagggcaagggggagatgaccacctacttcctc aatgggggccccagcagttag

Lipotes vexillifer (Yangtze River dolphin): 103075499 Help Entry 103075499         CDS       T03090                                  Gene name ADCY4 Definition (RefSeq) adenylate cyclase 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism lve  Lipotes vexillifer (Yangtze River dolphin) Pathway lve00230   Purine metabolism lve01100   Metabolic pathways lve01522   Endocrine resistance lve04015   Rap1 signaling pathway lve04020   Calcium signaling pathway lve04022   cGMP-PKG signaling pathway lve04024   cAMP signaling pathway lve04062   Chemokine signaling pathway lve04072   Phospholipase D signaling pathway lve04114   Oocyte meiosis lve04211   Longevity regulating pathway lve04213   Longevity regulating pathway - multiple species lve04261   Adrenergic signaling in cardiomyocytes lve04270   Vascular smooth muscle contraction lve04371   Apelin signaling pathway lve04540   Gap junction lve04611   Platelet activation lve04713   Circadian entrainment lve04714   Thermogenesis lve04723   Retrograde endocannabinoid signaling lve04724   Glutamatergic synapse lve04725   Cholinergic synapse lve04727   GABAergic synapse lve04742   Taste transduction lve04750   Inflammatory mediator regulation of TRP channels lve04911   Insulin secretion lve04912   GnRH signaling pathway lve04913   Ovarian steroidogenesis lve04914   Progesterone-mediated oocyte maturation lve04915   Estrogen signaling pathway lve04916   Melanogenesis lve04918   Thyroid hormone synthesis lve04921   Oxytocin signaling pathway lve04923   Regulation of lipolysis in adipocytes lve04925   Aldosterone synthesis and secretion lve04926   Relaxin signaling pathway lve04927   Cortisol synthesis and secretion lve04928   Parathyroid hormone synthesis, secretion and action lve04934   Cushing syndrome lve04935   Growth hormone synthesis, secretion and action lve04970   Salivary secretion lve04971   Gastric acid secretion lve04972   Pancreatic secretion lve04976   Bile secretion lve05032   Morphine addiction lve05163   Human cytomegalovirus infection lve05166   Human T-cell leukemia virus 1 infection lve05200   Pathways in cancer lve05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lve00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     103075499 (ADCY4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103075499 (ADCY4)    04371 Apelin signaling pathway     103075499 (ADCY4)    04020 Calcium signaling pathway     103075499 (ADCY4)    04072 Phospholipase D signaling pathway     103075499 (ADCY4)    04024 cAMP signaling pathway     103075499 (ADCY4)    04022 cGMP-PKG signaling pathway     103075499 (ADCY4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     103075499 (ADCY4)   09144 Cellular community - eukaryotes    04540 Gap junction     103075499 (ADCY4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103075499 (ADCY4)    04062 Chemokine signaling pathway     103075499 (ADCY4)   09152 Endocrine system    04911 Insulin secretion     103075499 (ADCY4)    04923 Regulation of lipolysis in adipocytes     103075499 (ADCY4)    04912 GnRH signaling pathway     103075499 (ADCY4)    04913 Ovarian steroidogenesis     103075499 (ADCY4)    04915 Estrogen signaling pathway     103075499 (ADCY4)    04914 Progesterone-mediated oocyte maturation     103075499 (ADCY4)    04921 Oxytocin signaling pathway     103075499 (ADCY4)    04926 Relaxin signaling pathway     103075499 (ADCY4)    04935 Growth hormone synthesis, secretion and action     103075499 (ADCY4)    04918 Thyroid hormone synthesis     103075499 (ADCY4)    04928 Parathyroid hormone synthesis, secretion and action     103075499 (ADCY4)    04916 Melanogenesis     103075499 (ADCY4)    04925 Aldosterone synthesis and secretion     103075499 (ADCY4)    04927 Cortisol synthesis and secretion     103075499 (ADCY4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     103075499 (ADCY4)    04270 Vascular smooth muscle contraction     103075499 (ADCY4)   09154 Digestive system    04970 Salivary secretion     103075499 (ADCY4)    04971 Gastric acid secretion     103075499 (ADCY4)    04972 Pancreatic secretion     103075499 (ADCY4)    04976 Bile secretion     103075499 (ADCY4)   09156 Nervous system    04724 Glutamatergic synapse     103075499 (ADCY4)    04727 GABAergic synapse     103075499 (ADCY4)    04725 Cholinergic synapse     103075499 (ADCY4)    04723 Retrograde endocannabinoid signaling     103075499 (ADCY4)   09157 Sensory system    04742 Taste transduction     103075499 (ADCY4)    04750 Inflammatory mediator regulation of TRP channels     103075499 (ADCY4)   09149 Aging    04211 Longevity regulating pathway     103075499 (ADCY4)    04213 Longevity regulating pathway - multiple species     103075499 (ADCY4)   09159 Environmental adaptation    04713 Circadian entrainment     103075499 (ADCY4)    04714 Thermogenesis     103075499 (ADCY4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103075499 (ADCY4)   09165 Substance dependence    05032 Morphine addiction     103075499 (ADCY4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     103075499 (ADCY4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     103075499 (ADCY4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103075499 (ADCY4)    05163 Human cytomegalovirus infection     103075499 (ADCY4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     103075499 (ADCY4) Enzymes [BR:lve01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      103075499 (ADCY4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc DUF1053 AC_N CD52 Motif Other DBs NCBI-GeneID:  103075499 NCBI-ProteinID:  XP_007447961 UniProt:  A0A340WGY9 LinkDB All DBs Position Un AA seq 1073 aa AA seqDB search MARLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLVIVLVGLLALLAVAWELASDPGFLTT MLCGLGGFSLLLGLASREQRLQRWTRPLSGLVWAALLALGLGFLFTGGVVSAWDQVSFFL FVIFTVYAMLPLGMRDAAAAGLASSLSHLLVLGLYLGPQPDSQPALLPQLAANAVLFLCG NVAGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMKAEIM ARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNELFGK FDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATGVDIN MRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEASGVPGRVHITGATLALLAGAYAV EDAAMEHGDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGPKMRPSLLMTRYLES WGAAKPFAHLSHVESPVSTSTPLPEKALSSFSPQWSLDRSRTPRGLDDELDTGDAKFFQV IEQLNSQKQWKQSEDFNPLTLYFREKEMEKEYRLSALPAFKYYAACTFLVFFSNFIIQML VTNRPPALTITYSITFLLFFLLLFVCFSEHLTKCVLKGPKMLHWLPTLSVLVATRPGLRV ALGTATILLVFSMAITSLVFLPAASNCPFLAPNVSSTASNLSWELPGSLPLISVPYSVHC CVLGFLSCSLFLHTSFELKLLLLLLWLAACCSLFLHSHAWLSDCLIARLYLGALDSRPGL LKEPKLMGAISFFVFFFTLLVLARQNEYYCRLDFLWKKKLRQEQEETETMENLTRLLLEN VLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESSINHEGLECLRLLNE IIADFDELLSKPKFSGVEKIKTICSTYMAATGLNATSGQDAQQDAEQSCSHLGTMVEFAV ALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVLG KIQVTQETACALQSLGYTCYSRGIIKVKGKGQLCTYFLNTDLTRTGPPSATLG NT seq 3222 nt NT seq  +upstreamnt  +downstreamnt atggcccgcctcttcagtccccggccgcctcccagcgaagacctcttctacgagacctac tacagcctgagccagcagtacccactgctgctactgcttctggtgatcgtgctcgtcggg ctcctggcgctgctcgctgttgcctgggagctggcctcagacccgggcttcctgaccact atgctgtgcgggctgggcggcttctcgctgctgctgggcctggcttcccgcgagcagcga ctgcagcgctggacgcgtcccctgtcgggcctcgtgtgggcagcgctgctcgcgctgggc ctcggcttcctcttcactgggggcgtggtgagcgcctgggaccaggtgtcctttttcctt tttgtcatcttcaccgtgtatgccatgttgcccttgggcatgcgggacgccgccgccgcg ggtctcgcctcttcactctcacacctgctggtcctcgggctgtatcttgggcctcagccg gactcacagcccgcgctcctgccacagctggcggcaaacgccgtgttgttcctgtgcggg aacgtggctggagcataccacaaggcgctgatggagcgcgcgctgcgcgccacgttccgg gaggcgcttagttccctgcactcccgccggaggctcgacacagagaagaagcaccaggaa caccttctcttgtccatccttcctgcctacctggcccgagagatgaaggcggagatcatg gcacggctgcaggccggacaggggtcacggccagagagcaccaacaacttccacagcctc tatgtcaagaggcaccagggagtgagcgtgctgtatgctgacatcgtgggcttcacgcgg ctggccagtgagtgctcccctaaggagttggtgctcatgctaaacgagctctttggcaag ttcgaccagatcgccaaggagcatgaatgcatgcggatcaagatcctgggagactgttac tactgtgtctccgggctgccgctctcgctgccagaccatgccatcaactgcgtgcgcatg gggctggacatgtgccgggccatcaggaagcttcgggcagccaccggcgtggatatcaac atgcgtgtgggtgtgcactcgggcagcgtgctctgcggggtcatcgggctgcagaagtgg cagtatgatgtctggtcccatgacgtcactctggccaaccacatggaggcgagtggagtg ccaggacgagtacatatcacaggggctacgctggcactgctggcaggggcttacgctgtg gaggatgcagccatggaacacggggacccatacctccgggagctaggggagccgacctac cttgtcatcgatccccgggctgaggaggaggacgagaagggcactgcaggcgggttgctg tcctctcttgagggccccaagatgcgtccatcactgttgatgacccgctacctggagtcc tggggtgcagccaagcctttcgcccacctgagccatgtggagagccctgtgtccacctcc acccctctcccggagaaggccctgtcttccttcagcccccagtggagcctggaccggagc cgtaccccccggggactagatgatgaactagacaccggggatgccaagttcttccaagtc atcgaacagctcaactctcagaaacagtggaaacagtcagaggacttcaacccattgacc ctgtacttccgggagaaggagatggagaaagagtatcggctctctgcactccccgccttc aaatactatgcagcctgcaccttcctggtttttttctccaacttcatcatccagatgctg gtgacaaacaggcccccagctctgaccatcacctatagcatcaccttcctcctcttcttc ctcctcctcttcgtctgcttctcagagcacctgacgaagtgtgtcttgaaaggccccaag atgctgcactggctgcccacactgtctgtcctagtggccacacggcccggactgcgagtt gccctgggcaccgctaccatcctgctcgtcttctccatggccattaccagcctggtcttc ttaccggcagcatcaaactgccctttcctggctcccaatgtgtcctccacagcttccaac ctctcctgggagctccctgggtccctgcctctcatcagcgtcccctactccgtgcactgc tgcgtgctggggttcctctcctgctccctcttcctgcacacgagcttcgagctgaagctg ctgctgctgctgctgtggctggcagcctgctgctccctcttcctgcactcccacgcctgg ctgtccgactgtctcatcgcccgcctctatctgggcgccttggactccaggccagggctg ctgaaggagcctaaactgatgggagcaatctccttctttgtcttcttcttcaccctcctg gtcctggctcggcagaatgagtattactgccgcctggacttcctgtggaagaagaagctg aggcaagagcaggaggagacagagacgatggaaaacctgactcggctgctcctggagaat gtgctccccgcgcacgtagccccccagttcatcggccagaatcggcgcaacgaggacctc taccaccagtcctacgagtgtgtttgtgtcctcttcgcctcagtcccagacttcaaggag ttttactctgaatccagcatcaaccacgaggggctagagtgtctgcggctgctcaatgag ataattgctgattttgatgagctgctctccaagcccaagttcagtggggtggagaaaatc aaaactatctgcagcacctacatggcggctacaggcttgaacgccacctccggacaggac gcacagcaggatgctgagcaaagctgcagccaccttggcaccatggtagagtttgccgtg gcccttgggtctaagctggacgtcatcaacaagcactcattcaacaacttccgcttgcgt gtggggttaaaccacggacctgtagtggccggagtgattggggcccagaaaccacaatat gacatctggggcaacacggtgaacgtggccagccgaatggagagtacaggcgtcctgggc aagatccaagtgacccaagagacagcctgcgccctgcagtccttaggctacacctgctac agccggggcatcatcaaggtcaaaggcaaagggcagctctgcacctacttcctgaacaca gatttgacacgaactggacctccctcggccaccctaggctga

Lipotes vexillifer (Yangtze River dolphin): 103076182 Help Entry 103076182         CDS       T03090                                  Gene name ADCY3 Definition (RefSeq) adenylate cyclase 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism lve  Lipotes vexillifer (Yangtze River dolphin) Pathway lve00230   Purine metabolism lve01100   Metabolic pathways lve01522   Endocrine resistance lve04015   Rap1 signaling pathway lve04020   Calcium signaling pathway lve04022   cGMP-PKG signaling pathway lve04024   cAMP signaling pathway lve04062   Chemokine signaling pathway lve04072   Phospholipase D signaling pathway lve04114   Oocyte meiosis lve04211   Longevity regulating pathway lve04213   Longevity regulating pathway - multiple species lve04261   Adrenergic signaling in cardiomyocytes lve04270   Vascular smooth muscle contraction lve04371   Apelin signaling pathway lve04540   Gap junction lve04611   Platelet activation lve04713   Circadian entrainment lve04714   Thermogenesis lve04723   Retrograde endocannabinoid signaling lve04724   Glutamatergic synapse lve04725   Cholinergic synapse lve04727   GABAergic synapse lve04740   Olfactory transduction lve04750   Inflammatory mediator regulation of TRP channels lve04911   Insulin secretion lve04912   GnRH signaling pathway lve04913   Ovarian steroidogenesis lve04914   Progesterone-mediated oocyte maturation lve04915   Estrogen signaling pathway lve04916   Melanogenesis lve04918   Thyroid hormone synthesis lve04921   Oxytocin signaling pathway lve04923   Regulation of lipolysis in adipocytes lve04925   Aldosterone synthesis and secretion lve04926   Relaxin signaling pathway lve04927   Cortisol synthesis and secretion lve04928   Parathyroid hormone synthesis, secretion and action lve04934   Cushing syndrome lve04935   Growth hormone synthesis, secretion and action lve04962   Vasopressin-regulated water reabsorption lve04970   Salivary secretion lve04971   Gastric acid secretion lve04972   Pancreatic secretion lve04976   Bile secretion lve05032   Morphine addiction lve05163   Human cytomegalovirus infection lve05166   Human T-cell leukemia virus 1 infection lve05200   Pathways in cancer lve05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lve00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     103076182 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103076182 (ADCY3)    04371 Apelin signaling pathway     103076182 (ADCY3)    04020 Calcium signaling pathway     103076182 (ADCY3)    04072 Phospholipase D signaling pathway     103076182 (ADCY3)    04024 cAMP signaling pathway     103076182 (ADCY3)    04022 cGMP-PKG signaling pathway     103076182 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     103076182 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     103076182 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103076182 (ADCY3)    04062 Chemokine signaling pathway     103076182 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     103076182 (ADCY3)    04923 Regulation of lipolysis in adipocytes     103076182 (ADCY3)    04912 GnRH signaling pathway     103076182 (ADCY3)    04913 Ovarian steroidogenesis     103076182 (ADCY3)    04915 Estrogen signaling pathway     103076182 (ADCY3)    04914 Progesterone-mediated oocyte maturation     103076182 (ADCY3)    04921 Oxytocin signaling pathway     103076182 (ADCY3)    04926 Relaxin signaling pathway     103076182 (ADCY3)    04935 Growth hormone synthesis, secretion and action     103076182 (ADCY3)    04918 Thyroid hormone synthesis     103076182 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     103076182 (ADCY3)    04916 Melanogenesis     103076182 (ADCY3)    04925 Aldosterone synthesis and secretion     103076182 (ADCY3)    04927 Cortisol synthesis and secretion     103076182 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     103076182 (ADCY3)    04270 Vascular smooth muscle contraction     103076182 (ADCY3)   09154 Digestive system    04970 Salivary secretion     103076182 (ADCY3)    04971 Gastric acid secretion     103076182 (ADCY3)    04972 Pancreatic secretion     103076182 (ADCY3)    04976 Bile secretion     103076182 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     103076182 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     103076182 (ADCY3)    04727 GABAergic synapse     103076182 (ADCY3)    04725 Cholinergic synapse     103076182 (ADCY3)    04723 Retrograde endocannabinoid signaling     103076182 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     103076182 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     103076182 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     103076182 (ADCY3)    04213 Longevity regulating pathway - multiple species     103076182 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     103076182 (ADCY3)    04714 Thermogenesis     103076182 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103076182 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     103076182 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     103076182 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     103076182 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103076182 (ADCY3)    05163 Human cytomegalovirus infection     103076182 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     103076182 (ADCY3) Enzymes [BR:lve01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      103076182 (ADCY3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N HNOBA Peptidase_S49_N Motif Other DBs NCBI-GeneID:  103076182 NCBI-ProteinID:  XP_007455568 UniProt:  A0A340X1W5 LinkDB All DBs Position Un AA seq 1141 aa AA seqDB search MPRTQGFSDPEYSAEYSAEYSVSLPSDPDRRVGRTHEISVRNSGSCLCLPRFMRLTFVPE SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSSDKLAPLAVAGVGLVLDII LFVLCRKGLLPTRVTRKVVPYLLWLLITAQVFCLGLNFSRAHAASDTVGWQAFFVFSFFI TLPLSLSPIVVISVVSCIVHTLVLGVTVAQQQRDGLKGMQLLREILANVFLYLCAIVVGI MSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDESQ KDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQL RIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTVL GGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGDGGSRCDY LDEKGIETYLIIATKPEVKRTAAQNGLSGSALLNGVPPSSKPGSPALIETKEPNGSIHTS GSTSEEPDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESAQVVR KRNTFFLSMRFTDREMETRYSVEKEKQSGAAFSCSCVVLLCTALVEILIDPWLMTNYVTF VVGEVLLLTLTVCSLAAIFPRAFPKKIVAFSTWIDRTRWARNTWAMLAIFILVMANVVDM LSCLQYYMGPTNGTSGVQIEDGCVENPKYYNYVAVLSLIATIMLVQVSHMVKLTLMLLIA GAVAVINIYAWRPIFDEYDRRRFQEHDFPMVALEKMQVPSSPGLNGTDRLPLVPSRCSMT GMIFVMTLGFYYFCRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEHVARH FLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDFDSLL DNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSNKVERSDKERWQHLADLADFALAM KDTLANINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVMGNI QVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGREKPATFPNGSSVTLPHQVVDN S NT seq 3426 nt NT seq  +upstreamnt  +downstreamnt atgccgaggacccagggcttctccgatcctgagtactcggccgaatactcggccgagtac tccgtcagcctgccctctgaccctgaccgcagggtgggccggacccatgagatctctgtc cgcaactcgggatcctgcctgtgcctgcctcgcttcatgcggctgaccttcgtgccggag tccttggagaacctgtaccagacctacttcaaaaggcagcgccacgagacgctgctggtg ctggtggtattcgcggccctcttcgactgctacgtggtggtcatgtgcgcggtggtcttc tccagtgacaagctggctcccctggctgtggccggggtcgggctggtgttggacatcatc ctctttgtgctctgcagaaaggggctgctgcccacccgggtcacccggaaagtggtgccc tacctgctgtggctgctgataacagcccaggtcttctgcctgggcctgaacttctcccgc gcgcacgcagccagcgacacggtgggctggcaggccttctttgtcttctccttcttcatc acgctgcccctcagcctcagccccatcgtcgtcatctctgtggtctcctgcatcgtgcac acgcttgtcttgggggtcaccgtggcccagcagcagcgggacgggctgaaggggatgcag ttgctgagggagattctggccaatgtcttcctctatctgtgcgccatcgttgtgggcatc atgtcctactacatggcggaccgcaagcaccgcaaggccttcctggaggcccgccagtcg ctggaggtgaagatgaacctggaggagcagagccagcagcaggagaaccttatgctttcc atcctgcccaagcacgtggcagacgagatgctgaaggacatgaaaaaggacgagagccag aaggaccagcagcagttcaacaccatgtacatgtaccgccacgagaatgtcagcatcctg tttgccgacatcgtgggcttcacccagctgtcctcagcctgcagcgcccaagagctcgtg aagctcctcaatgagctctttgcccgcttcgacaagctggcggccaaataccaccagctg cggattaagattctgggcgactgttactactgcatctgtgggctgcctgactaccgcgag gaccacgccgtctgctccatcctcatggggctcgccatggtggaggccatctcgtatgta cgggagaagacgaagaccggggtggacatgcgagtcggggtgcacacgggcaccgtgctg gggggtgtcctgggccagaagcgctggcagtacgacgtgtggtccaccgatgtcaccgtg gccaacaagatggaggccggcggcatccccgggcgtgtgcacatctcccagagcaccatg gactgcctgaaaggcgagtttgacgtggagccaggtgatgggggcagccgctgtgattac ctggatgagaagggcatcgaaacctacctcatcattgcgaccaagccagaggtgaagagg acagctgcccaaaatggcctcagcggctcagctctgctgaacggagtgccaccttcctca aagcccggctcccctgccctcattgagaccaaggagcctaacgggagcatccacaccagc ggctccacgtccgaggagccagatgcccaggctgacaacccctcattccccaaccctcgc cggaggctgcggcttcaggacctggccgatcgcgtggtggacgcctccgaggatgagcac gagctcaaccagctgctcaacgaggccctgctggagcgggagtccgcccaggtggtgagg aagagaaacaccttcttcctgtccatgcggttcacggaccgcgagatggaaacgcgctac tcggtggagaaggagaagcagagcggggccgccttcagctgttcctgcgtcgtcctgctc tgcaccgccctggttgagattctcatcgacccctggctgatgacaaactatgtgaccttt gtggttggcgaggtcctgctcctgaccctgactgtctgctcgctggctgccatctttcct cgggcctttcctaagaagatcgtggccttctcgacttggatcgaccggacgcgctgggcc aggaacacctgggccatgctggccatcttcattctggtcatggcaaacgtcgtggacatg cttagctgtctccagtactacatgggacccaccaacggcacctcaggggtgcagatagag gacggctgcgtggagaaccccaagtattacaactacgtcgctgtgctgtccctcatcgcc accatcatgctggtgcaggtcagccacatggtcaagctgacactcatgctgctcatcgca ggggctgtggccgtcatcaacatctacgcctggcgccccatctttgatgaatacgaccgc agacgcttccaagaacacgactttccgatggtggccttagagaagatgcaggtaccttcc agccctgggctcaatggcactgacaggctgcccctggtgccgtccaggtgctcgatgaca gggatgatcttcgtcatgacgctcggcttctactacttctgccgccacgtggagaagctg gcacgaacactgttcttatggaagattgaggtccacgaccagaaggaacgtgtctatgaa atgagacgctggaacgaggccttggtcactaacatgttgcctgagcacgtggcacgccat ttcctggggtccaagaagagagacgaggagctgtacagtcagtcttatgacgagattgga gtcatgtttgcctccctgcccaactttgccgacttctacacagaggagagcatcaataac ggtggcattgagtgtctgcgcttcctcaatgagatcatctcagattttgactctctcctg gacaatcccaagtttcgggtcatcaccaagatcaaaaccattggcagcacctacatggca gcttcaggagtcaccccagatgtcaacaccaatggctttaccagctccaacaaggtagag aggtcggacaaggagcgctggcagcacctggcagatctggccgacttcgcgctcgccatg aaagacacgctcgccaacatcaacaaccagtccttcaataacttcatgttgcgcatcggc atgaacaaaggaggggtactggctggcgtcatcggagcccggaaaccacactatgacatc tggggcaatacagtcaacgttgccagcaggatggagtccacaggggtcatgggcaacatt caggtggtggaagaaactcaagtcatccttcgagagtacggcttccgctttgtgaggaga gggcccatctttgtgaaagggaagggggagctgctgacctttttcttgaaggggcgagag aagccagccacgttccctaatggctcctcggttacactgccccaccaggtagtagacaac tcctga

Lipotes vexillifer (Yangtze River dolphin): 103078677 Help Entry 103078677         CDS       T03090                                  Gene name ADCY7 Definition (RefSeq) adenylate cyclase 7   KO K08047   adenylate cyclase 7 [EC:4.6.1.1] Organism lve  Lipotes vexillifer (Yangtze River dolphin) Pathway lve00230   Purine metabolism lve01100   Metabolic pathways lve01522   Endocrine resistance lve04015   Rap1 signaling pathway lve04020   Calcium signaling pathway lve04022   cGMP-PKG signaling pathway lve04024   cAMP signaling pathway lve04062   Chemokine signaling pathway lve04072   Phospholipase D signaling pathway lve04114   Oocyte meiosis lve04211   Longevity regulating pathway lve04213   Longevity regulating pathway - multiple species lve04261   Adrenergic signaling in cardiomyocytes lve04270   Vascular smooth muscle contraction lve04371   Apelin signaling pathway lve04540   Gap junction lve04611   Platelet activation lve04713   Circadian entrainment lve04714   Thermogenesis lve04723   Retrograde endocannabinoid signaling lve04724   Glutamatergic synapse lve04725   Cholinergic synapse lve04727   GABAergic synapse lve04750   Inflammatory mediator regulation of TRP channels lve04911   Insulin secretion lve04912   GnRH signaling pathway lve04913   Ovarian steroidogenesis lve04914   Progesterone-mediated oocyte maturation lve04915   Estrogen signaling pathway lve04916   Melanogenesis lve04918   Thyroid hormone synthesis lve04921   Oxytocin signaling pathway lve04923   Regulation of lipolysis in adipocytes lve04925   Aldosterone synthesis and secretion lve04926   Relaxin signaling pathway lve04927   Cortisol synthesis and secretion lve04928   Parathyroid hormone synthesis, secretion and action lve04934   Cushing syndrome lve04935   Growth hormone synthesis, secretion and action lve04970   Salivary secretion lve04971   Gastric acid secretion lve04972   Pancreatic secretion lve04976   Bile secretion lve05032   Morphine addiction lve05163   Human cytomegalovirus infection lve05166   Human T-cell leukemia virus 1 infection lve05200   Pathways in cancer lve05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lve00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     103078677 (ADCY7)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103078677 (ADCY7)    04371 Apelin signaling pathway     103078677 (ADCY7)    04020 Calcium signaling pathway     103078677 (ADCY7)    04072 Phospholipase D signaling pathway     103078677 (ADCY7)    04024 cAMP signaling pathway     103078677 (ADCY7)    04022 cGMP-PKG signaling pathway     103078677 (ADCY7)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     103078677 (ADCY7)   09144 Cellular community - eukaryotes    04540 Gap junction     103078677 (ADCY7)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103078677 (ADCY7)    04062 Chemokine signaling pathway     103078677 (ADCY7)   09152 Endocrine system    04911 Insulin secretion     103078677 (ADCY7)    04923 Regulation of lipolysis in adipocytes     103078677 (ADCY7)    04912 GnRH signaling pathway     103078677 (ADCY7)    04913 Ovarian steroidogenesis     103078677 (ADCY7)    04915 Estrogen signaling pathway     103078677 (ADCY7)    04914 Progesterone-mediated oocyte maturation     103078677 (ADCY7)    04921 Oxytocin signaling pathway     103078677 (ADCY7)    04926 Relaxin signaling pathway     103078677 (ADCY7)    04935 Growth hormone synthesis, secretion and action     103078677 (ADCY7)    04918 Thyroid hormone synthesis     103078677 (ADCY7)    04928 Parathyroid hormone synthesis, secretion and action     103078677 (ADCY7)    04916 Melanogenesis     103078677 (ADCY7)    04925 Aldosterone synthesis and secretion     103078677 (ADCY7)    04927 Cortisol synthesis and secretion     103078677 (ADCY7)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     103078677 (ADCY7)    04270 Vascular smooth muscle contraction     103078677 (ADCY7)   09154 Digestive system    04970 Salivary secretion     103078677 (ADCY7)    04971 Gastric acid secretion     103078677 (ADCY7)    04972 Pancreatic secretion     103078677 (ADCY7)    04976 Bile secretion     103078677 (ADCY7)   09156 Nervous system    04724 Glutamatergic synapse     103078677 (ADCY7)    04727 GABAergic synapse     103078677 (ADCY7)    04725 Cholinergic synapse     103078677 (ADCY7)    04723 Retrograde endocannabinoid signaling     103078677 (ADCY7)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     103078677 (ADCY7)   09149 Aging    04211 Longevity regulating pathway     103078677 (ADCY7)    04213 Longevity regulating pathway - multiple species     103078677 (ADCY7)   09159 Environmental adaptation    04713 Circadian entrainment     103078677 (ADCY7)    04714 Thermogenesis     103078677 (ADCY7)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103078677 (ADCY7)   09165 Substance dependence    05032 Morphine addiction     103078677 (ADCY7)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     103078677 (ADCY7)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     103078677 (ADCY7)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103078677 (ADCY7)    05163 Human cytomegalovirus infection     103078677 (ADCY7)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     103078677 (ADCY7) Enzymes [BR:lve01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      103078677 (ADCY7) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc DUF1053 AC_N Motif Other DBs NCBI-GeneID:  103078677 NCBI-ProteinID:  XP_007459540 UniProt:  A0A340XKH5 LinkDB All DBs Position Un AA seq 1078 aa AA seqDB search MPAKGRYFLNEGEEDPNHDTLYEKYRLTSQHGPLLLTLLLVAITACVVLIIIAFSYGDPS RHQAVLGTAFFTLAVFVALYALVYVECLVRRWLRASALLIWACLVTLGYVLVFDSWMKEA CDWEQVPFFLFVVFVVYTLLPFSTRGAVVAGVVSSTSHLLVLGALMGAFTTPSVRVGLQL LANAVVFLCGNLTGAFHKHQMQDASRDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAH ISMGMKLAIIERLKERGDRRYLPDNNFHSLYVKRHQNVSILYADIVGFTQLASDCSPKEL VVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPSHARNCVKMGLDMCEAIKQ VREATGVDISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT LNHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSLHLTKSKGDATLKMRA SVRMTRYLESWGAARPFAHLNQRENVSSNETPVPHGRRPKAIPLRRHRTPDRSASPKGRS EDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPIPRARYYFACA GLVFICILLVHALLMPRMAALGVSFGLVACVLGLVLGLCFAHELLRCCPARGALRAISER VETQPLLRVSLAVLTIGSLLAVAVVNLPLMPFPAPGLPAGNETGPGAVSSWERALCKLLP YYTCSCILAFIACSVFLRMSLELKVVLLTVALVAYLVLFNISPCWQWDCCGHSLGNLTKT NGTLSSPSCSWDLKTMINFYLVLFYTTLIMLSRQIDYYCRLDCLWKRKFKKEHEEFETME NVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKEGL ECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSIPSGHENQDLERQHAHIG IMVEFSTALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVASRM ESTGELGKIQVTEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKFQGLGLN NT seq 3237 nt NT seq  +upstreamnt  +downstreamnt atgccggccaaggggcgttacttcctcaacgagggcgaggaggaccccaaccacgacacg ctctacgagaagtaccgcctcaccagccagcatgggccgctgctactcacactcctgttg gtggccatcactgcctgtgtcgtcctcatcatcatcgccttcagctacggggacccctcc agacaccaggctgtcctggggacggcgttcttcacgcttgctgtgtttgtggctctctac gcgctcgtgtatgttgagtgcctcgtccgccggtggctcagggcctcggcgctactcatc tgggcctgccttgtgacgctgggctacgtgctggtgtttgactcatggatgaaggaggcc tgtgactgggagcaggtgcccttcttcctgttcgtggtcttcgtggtgtacacgctgctg cccttcagcacgcggggtgccgtcgtggccggggtcgtctccagcacctcccacctcctg gtgctcggcgctctgatgggggccttcaccacgcccagcgtccgggtagggctgcagctg ctggccaatgctgtggtcttcctgtgcgggaacctcacgggcgccttccacaagcaccag atgcaggatgcctcccgagacctcttcacctacactgtgaagtgcatccagatccgtcgt aaactgcgcatcgagaagcgccagcaggagaacctgctgctgtccgtgctgcctgcccac atctccatgggcatgaagctggccatcatcgagcggctcaaggagcgcggggaccgccgc tacctgcctgacaacaacttccatagcctctacgtcaagcggcaccagaacgtcagcatc ctctatgctgacatcgtgggcttcacgcagctggccagcgactgctccccaaaagagttg gtggtggtgctgaacgagctcttcggaaagttcgaccagatcgccaaggccaatgaatgc atgcggatcaagatcctgggcgactgctactactgcgtgtcaggcttgcccgtgtccctg cccagccacgcccgcaactgtgtgaagatggggctggacatgtgtgaggccattaagcag gtgcgggaggccacaggcgtggacatcagcatgcgtgtgggcatacactcggggaacgtg ctgtgcggtgtcatcgggctgcgcaagtggcagtatgatgtgtggtcccatgacgtgtcc ctggccaacaggatggaggcagctggagtccctggccgggtgcacatcacagaggcgacg ctgaaccacctggacaaggcgtatgaggtggaggacgggcacgggcagcagcgggacccc tacctgaaggagatgaacatccgcacctacctggtcatcgacccccggagccagcagccg cccccgcccagcctacacctcaccaagtccaagggggacgcgaccctgaagatgcgggcc tccgtgcgcatgacccgctacctcgagtcctggggggcggcgcggcccttcgcacacctc aaccaacgcgagaacgtgagcagcaatgagacccctgtgccccacgggcggaggcccaag gccattcccctacggcgccaccggacccctgacagaagcgcgtcccccaaggggcggtca gaggatgactcatatgatgatgagatgctgtcagccatcgagggcctcagctccacgaga ccctgctgctccaagtctgatgacttctacacctttgggtccatcttcctggagaagggc ttcgagcgagagtaccgcctggcacccatcccgcgggcccgctactactttgcttgtgcc ggccttgtgttcatctgcatcctgctcgtccatgccctgctgatgcccaggatggcggct ctgggtgtgtcctttgggctggtggcctgtgtgctcgggctggtactaggcttgtgcttt gcccatgagctcttgaggtgctgcccagcccggggcgcgctccgagccatctccgagagg gtggagacgcagcccctgctgcgggtgtccctggccgtcctgaccatcggcagcctgctc gccgtcgccgttgtcaacctgccgctgatgcctttcccggccccagggctgcctgctggg aacgagacgggcccgggggccgtgagcagctgggagagggccctgtgcaagctcctcccg tattacacctgcagctgcatcctggccttcatcgcctgctctgtcttcctgcggatgagc ctggagctgaaggtcgtgctgttgacagtggccttggtggcctacctggtgctcttcaac atctccccgtgctggcagtgggactgctgtggccacagcctgggcaacctcaccaagacc aatggcaccctcagctccccgtcctgttcatgggatctgaagacaatgatcaatttctac ctggtcctgttttacaccaccctcatcatgctctccagacagattgactattactgccgc ttggactgtctgtggaagaggaagttcaagaaggaacacgaggagtttgaaaccatggag aatgtgaaccgccttcttctagagaatgtcctgccagcgcacgtggccgcccacttcatt ggtgacaagttaaatgaggactggtaccaccagtcctatgactgcgtgtgtgtcatgttt gcatctgtgccggacttcaaagtattctacacggagtgcgacgtcaacaaggaagggctg gagtgcctgcgcctgttgaacgagatcatagctgactttgacgagctgctgttaaagccc aagttcagtggtgtggagaagatcaagaccatcggcagcacgtacatggcagctgcaggg ctcagcatcccctcagggcacgagaaccaggacctggagcggcagcacgcccacatcggc atcatggtggagttcagcaccgccctgatgagcaagctggatggcatcaaccggcactcc ttcaactccttccgcctccgagttggcataaaccacgggcccgtgattgctggagtgatt ggggcacgaaaacctcagtacgacatctggggaaacacggtcaatgttgccagtcgaatg gagagcaccggagaacttgggaaaatccaggttactgaagagacatgtaccatcctccag ggactaggttattcttgtgaatgccgcggactgattaacgtcaaaggcaaaggcgaactg cggacttactttgtctgtacggatactgccaagtttcaagggttggggctgaactga

Lipotes vexillifer (Yangtze River dolphin): 103081539 Help Entry 103081539         CDS       T03090                                  Gene name ADCY1 Definition (RefSeq) adenylate cyclase 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism lve  Lipotes vexillifer (Yangtze River dolphin) Pathway lve00230   Purine metabolism lve01100   Metabolic pathways lve01522   Endocrine resistance lve04015   Rap1 signaling pathway lve04020   Calcium signaling pathway lve04022   cGMP-PKG signaling pathway lve04024   cAMP signaling pathway lve04062   Chemokine signaling pathway lve04072   Phospholipase D signaling pathway lve04114   Oocyte meiosis lve04211   Longevity regulating pathway lve04213   Longevity regulating pathway - multiple species lve04261   Adrenergic signaling in cardiomyocytes lve04270   Vascular smooth muscle contraction lve04371   Apelin signaling pathway lve04540   Gap junction lve04611   Platelet activation lve04713   Circadian entrainment lve04714   Thermogenesis lve04720   Long-term potentiation lve04723   Retrograde endocannabinoid signaling lve04724   Glutamatergic synapse lve04725   Cholinergic synapse lve04727   GABAergic synapse lve04750   Inflammatory mediator regulation of TRP channels lve04911   Insulin secretion lve04912   GnRH signaling pathway lve04913   Ovarian steroidogenesis lve04914   Progesterone-mediated oocyte maturation lve04915   Estrogen signaling pathway lve04916   Melanogenesis lve04918   Thyroid hormone synthesis lve04921   Oxytocin signaling pathway lve04923   Regulation of lipolysis in adipocytes lve04925   Aldosterone synthesis and secretion lve04926   Relaxin signaling pathway lve04927   Cortisol synthesis and secretion lve04928   Parathyroid hormone synthesis, secretion and action lve04934   Cushing syndrome lve04935   Growth hormone synthesis, secretion and action lve04970   Salivary secretion lve04971   Gastric acid secretion lve04972   Pancreatic secretion lve04976   Bile secretion lve05032   Morphine addiction lve05142   Chagas disease lve05146   Amoebiasis lve05163   Human cytomegalovirus infection lve05166   Human T-cell leukemia virus 1 infection lve05200   Pathways in cancer lve05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lve00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     103081539 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103081539 (ADCY1)    04371 Apelin signaling pathway     103081539 (ADCY1)    04020 Calcium signaling pathway     103081539 (ADCY1)    04072 Phospholipase D signaling pathway     103081539 (ADCY1)    04024 cAMP signaling pathway     103081539 (ADCY1)    04022 cGMP-PKG signaling pathway     103081539 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     103081539 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     103081539 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103081539 (ADCY1)    04062 Chemokine signaling pathway     103081539 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     103081539 (ADCY1)    04923 Regulation of lipolysis in adipocytes     103081539 (ADCY1)    04912 GnRH signaling pathway     103081539 (ADCY1)    04913 Ovarian steroidogenesis     103081539 (ADCY1)    04915 Estrogen signaling pathway     103081539 (ADCY1)    04914 Progesterone-mediated oocyte maturation     103081539 (ADCY1)    04921 Oxytocin signaling pathway     103081539 (ADCY1)    04926 Relaxin signaling pathway     103081539 (ADCY1)    04935 Growth hormone synthesis, secretion and action     103081539 (ADCY1)    04918 Thyroid hormone synthesis     103081539 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     103081539 (ADCY1)    04916 Melanogenesis     103081539 (ADCY1)    04925 Aldosterone synthesis and secretion     103081539 (ADCY1)    04927 Cortisol synthesis and secretion     103081539 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     103081539 (ADCY1)    04270 Vascular smooth muscle contraction     103081539 (ADCY1)   09154 Digestive system    04970 Salivary secretion     103081539 (ADCY1)    04971 Gastric acid secretion     103081539 (ADCY1)    04972 Pancreatic secretion     103081539 (ADCY1)    04976 Bile secretion     103081539 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     103081539 (ADCY1)    04727 GABAergic synapse     103081539 (ADCY1)    04725 Cholinergic synapse     103081539 (ADCY1)    04720 Long-term potentiation     103081539 (ADCY1)    04723 Retrograde endocannabinoid signaling     103081539 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     103081539 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     103081539 (ADCY1)    04213 Longevity regulating pathway - multiple species     103081539 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     103081539 (ADCY1)    04714 Thermogenesis     103081539 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103081539 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     103081539 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     103081539 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     103081539 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103081539 (ADCY1)    05163 Human cytomegalovirus infection     103081539 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     103081539 (ADCY1)    05142 Chagas disease     103081539 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     103081539 (ADCY1) Enzymes [BR:lve01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      103081539 (ADCY1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N DUF1053 HNOBA Motif Other DBs NCBI-GeneID:  103081539 NCBI-ProteinID:  XP_007447087 UniProt:  A0A340WHT5 LinkDB All DBs Position Un AA seq 1134 aa AA seqDB search MAGAPRGRGGGGGGGGAGESGGAERAAGPGGRRGLRACNEEFACPELEALFRGYTLRLEQ AATLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQ LQQVGQLALLFSLTFALLCCPFALGGPAGAHAGAAAVPVAADQGVWQLLLVTFVSYALLP VRSLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFLGVNMYGVFVRILAERS QRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQR HDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVS GLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDV WSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKTHNIETFFIVP SHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRA LRTASEKLRNRSSFSTNVVYTTPGTRVNRYIGRLLEARQMELEMADLGFFTLKYKQAERE RKYHQLQDEYFTSAVILALILAALFGLVYLLIIPQSVAVLLLLVFCICFLVACVLYLHIT RVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWNSSPNGSLVILSSGRRDRV LPSPPCESAPHALLCGLVGTLPLAVFLRVSSLPKMILLAVLTTSYILVLELGGYTKAVGG DAVSGRSFEPIVAILLFSCTLALHARQVDVKLRLDYLWAAQAEEERGDMERVKLDNKRIL FNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLL NEIIADFDELMDRDFYKDLEKIKTIGSTYMAAVGLAPAAGTKAKKCISSHLSTLADFAIE MFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGR IQVTEEVHRLLRRGCYRFVCRGKVSVKGKGEMLTYFLEGRTDGSGSQNRSVNSERKMCPY GRAGLQTRLATGHPPVPPAAGLPVRAGPAALQGSGLAPCPPGHHLPPGAAGKEA NT seq 3405 nt NT seq  +upstreamnt  +downstreamnt atggcgggggcgccgcgcggccgaggcggcggcggaggcggaggcggcgcgggcgagtct gggggcgccgagcgggcggcggggccgggcggccggcgcgggctacgggcgtgcaacgag gagttcgcgtgccccgagctggaggcgctgttccgcggctacacgctgcggctggagcag gcggccacgctgaaggcgctggccgtgctcagcctactggcgggcgcgctggccctggcc gagctgctgggcgcgccggggcccgcgcccggcctggccaagggctcgcaccccgtgcac tgcgtgctcttcctggcgctgctcgtggtcaccaacgtccgctcgctgcaggtgccccag ctgcagcaggtcggccagctcgcgctgctcttcagcctcaccttcgcgctgctctgctgt cccttcgcgctcggcggccccgccggggcccacgcaggggcggcagcggtgccggtggca gccgaccagggcgtctggcagctccttttggtcaccttcgtgtcctatgccctgctgccc gtgcgcagcctgctggccatcggcttcgggctcgtggtggccgcctcgcatttgctggtc acggctaccttggtccccgccaagcgcccacgtctctggaggacgctcggtgccaacgcc ctgctcttccttggcgtgaacatgtacggggtcttcgtgaggatcctggctgagcgctcc cagaggaaggccttcctgcaggcccggaactgcatcgaggaccggctgaggctggaggat gagaatgagaagcaggagcggctgctcatgagtctcctgccccggaacgtcgccatggag atgaaggaggacttcctgaagccccccgagaggattttccacaagatctacatccagcgg catgacaacgtgagcatcctctttgcagacatcgtgggcttcacgggcttggcgtcgcag tgcacggcccaggagctggtgaaactcctcaatgagctcttcggcaagtttgacgaactg gccacggagaaccactgccgtcgcatcaagatcctgggagactgctactactgcgtgtcc ggcctcactcagcccaagactgaccacgcccactgctgtgtggagatgggcctggacatg atcgacaccatcacgtccgtggccgaggccactgaggtggacctgaacatgcgcgtgggg ctgcacaccggcagagtcctctgcggggtcctgggcctgcgcaagtggcagtacgacgtg tggtccaacgacgtgaccctggcgaacgtcatggaagccgccggcctgcctgggaaggtt cacatcacaaagaccaccctggcgtgcctgaatggtgactatgaggtggagccgggccat ggacacgagaggaacagttttctgaaaactcacaacattgagacctttttcatcgtgccc tcccatcggcgaaagatatttccagggctgattctctcagatataaaaccggccaagaga atgaagttcaagaccgtgtgctacctgctggtgcagctcatgcactgccggaagatgttc aaggctgagatccctttctccaatgtcatgacctgcgaggacgacgacaagcggagggca ctgagaacagcctcggaaaaactcagaaaccgctcatctttctctacaaacgttgtctac accacccctgggacacgcgtcaacaggtacattggacgcctcctggaagcccgccagatg gagctggagatggcggacctgggcttcttcacgctaaagtacaagcaggccgaacgagag cgaaagtatcaccagcttcaggacgagtatttcaccagcgccgtcattctggccctcatc ctggccgccttatttggccttgtctaccttctaataatcccgcagagcgtggccgtcctc ctcctgctggtgttctgcatatgcttcctggtggcctgtgtcctgtatctacacatcacc cgggtccagtgttttccagggtgcctgacgatccagatccgcaccgtcctgtgtatcttc atcgtggtcttaatctactccgtggcccaaggctgtgtggtgggctgcctgccttgggcc tggaactccagtcccaatgggtccctggtgatcctgtcgtctgggcgccgggaccgcgtg ctgccctccccgccctgcgagtctgcaccccacgccctgctgtgtggcctcgtgggcacc ctcccactggctgtattcctgcgggtgtcctccttgccaaaaatgatcctgcttgccgtg cttaccacctcctacatcctcgtcctggagctcggcgggtacacgaaggccgtggggggt gacgccgtctcgggccgcagctttgagccgattgtggccatcctcctgttctcgtgcacg ctggccctgcacgcccggcaggtggacgtcaagctgcggctggactacctgtgggccgca caggcagaggaggagaggggcgacatggagagggtgaagctggacaacaagaggattctc ttcaacctcctgccggcccacgtcgcccagcacttcctcatgtccaacccccgaaacatg gacctgtactaccagtcgtactcgcaggtgggggtcatgttcgcctccatccccaacttc aatgacttctacatcgagctggatggcaacaacatgggcgtggagtgtctgcgcctactc aacgagatcatcgccgactttgacgagctcatggacagagacttttacaaggacctggag aagatcaagaccatcggaagcacctacatggctgccgtggggctggcgcccgcggccggg accaaggctaagaagtgcatctcctcccacctcagcacattggcagattttgccatcgag atgtttgacgtcctggatgagatcaactaccagtcttacaacgactttgtgctccgtgtt ggcatcaacgttggccccgtggtggctggagtgatcggggctcgcaggccgcagtacgac atctggggaaatacggtcaacgtggccagtcggatggacagcaccggcgtccagggcaga atccaggtcacggaggaagttcacaggctgctgcggcggggctgctaccgcttcgtgtgc cgaggcaaagtcagtgtcaagggcaagggtgagatgctgacatacttcctggaaggcagg accgacggaagcggctcccaaaacaggtccgtgaactcagagcggaaaatgtgtccttac gggagagccggcctccagaccagactggccacgggccaccccccggtgccccctgcggcc ggcctcccagtcagagccgggccagcggctctgcagggctcggggcttgccccctgcccc ccaggccaccacctgccccccggagcagctgggaaggaggcttag

Lipotes vexillifer (Yangtze River dolphin): 103084817 Help Entry 103084817         CDS       T03090                                  Gene name ADCY2 Definition (RefSeq) adenylate cyclase 2   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism lve  Lipotes vexillifer (Yangtze River dolphin) Pathway lve00230   Purine metabolism lve01100   Metabolic pathways lve01522   Endocrine resistance lve04015   Rap1 signaling pathway lve04020   Calcium signaling pathway lve04022   cGMP-PKG signaling pathway lve04024   cAMP signaling pathway lve04062   Chemokine signaling pathway lve04072   Phospholipase D signaling pathway lve04114   Oocyte meiosis lve04211   Longevity regulating pathway lve04213   Longevity regulating pathway - multiple species lve04261   Adrenergic signaling in cardiomyocytes lve04270   Vascular smooth muscle contraction lve04371   Apelin signaling pathway lve04540   Gap junction lve04611   Platelet activation lve04713   Circadian entrainment lve04714   Thermogenesis lve04723   Retrograde endocannabinoid signaling lve04724   Glutamatergic synapse lve04725   Cholinergic synapse lve04727   GABAergic synapse lve04750   Inflammatory mediator regulation of TRP channels lve04911   Insulin secretion lve04912   GnRH signaling pathway lve04913   Ovarian steroidogenesis lve04914   Progesterone-mediated oocyte maturation lve04915   Estrogen signaling pathway lve04916   Melanogenesis lve04918   Thyroid hormone synthesis lve04921   Oxytocin signaling pathway lve04922   Glucagon signaling pathway lve04923   Regulation of lipolysis in adipocytes lve04925   Aldosterone synthesis and secretion lve04926   Relaxin signaling pathway lve04927   Cortisol synthesis and secretion lve04928   Parathyroid hormone synthesis, secretion and action lve04934   Cushing syndrome lve04935   Growth hormone synthesis, secretion and action lve04970   Salivary secretion lve04971   Gastric acid secretion lve04972   Pancreatic secretion lve04976   Bile secretion lve05032   Morphine addiction lve05163   Human cytomegalovirus infection lve05166   Human T-cell leukemia virus 1 infection lve05200   Pathways in cancer lve05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lve00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     103084817 (ADCY2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103084817 (ADCY2)    04371 Apelin signaling pathway     103084817 (ADCY2)    04020 Calcium signaling pathway     103084817 (ADCY2)    04072 Phospholipase D signaling pathway     103084817 (ADCY2)    04024 cAMP signaling pathway     103084817 (ADCY2)    04022 cGMP-PKG signaling pathway     103084817 (ADCY2)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     103084817 (ADCY2)   09144 Cellular community - eukaryotes    04540 Gap junction     103084817 (ADCY2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103084817 (ADCY2)    04062 Chemokine signaling pathway     103084817 (ADCY2)   09152 Endocrine system    04911 Insulin secretion     103084817 (ADCY2)    04922 Glucagon signaling pathway     103084817 (ADCY2)    04923 Regulation of lipolysis in adipocytes     103084817 (ADCY2)    04912 GnRH signaling pathway     103084817 (ADCY2)    04913 Ovarian steroidogenesis     103084817 (ADCY2)    04915 Estrogen signaling pathway     103084817 (ADCY2)    04914 Progesterone-mediated oocyte maturation     103084817 (ADCY2)    04921 Oxytocin signaling pathway     103084817 (ADCY2)    04926 Relaxin signaling pathway     103084817 (ADCY2)    04935 Growth hormone synthesis, secretion and action     103084817 (ADCY2)    04918 Thyroid hormone synthesis     103084817 (ADCY2)    04928 Parathyroid hormone synthesis, secretion and action     103084817 (ADCY2)    04916 Melanogenesis     103084817 (ADCY2)    04925 Aldosterone synthesis and secretion     103084817 (ADCY2)    04927 Cortisol synthesis and secretion     103084817 (ADCY2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     103084817 (ADCY2)    04270 Vascular smooth muscle contraction     103084817 (ADCY2)   09154 Digestive system    04970 Salivary secretion     103084817 (ADCY2)    04971 Gastric acid secretion     103084817 (ADCY2)    04972 Pancreatic secretion     103084817 (ADCY2)    04976 Bile secretion     103084817 (ADCY2)   09156 Nervous system    04724 Glutamatergic synapse     103084817 (ADCY2)    04727 GABAergic synapse     103084817 (ADCY2)    04725 Cholinergic synapse     103084817 (ADCY2)    04723 Retrograde endocannabinoid signaling     103084817 (ADCY2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     103084817 (ADCY2)   09149 Aging    04211 Longevity regulating pathway     103084817 (ADCY2)    04213 Longevity regulating pathway - multiple species     103084817 (ADCY2)   09159 Environmental adaptation    04713 Circadian entrainment     103084817 (ADCY2)    04714 Thermogenesis     103084817 (ADCY2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103084817 (ADCY2)   09165 Substance dependence    05032 Morphine addiction     103084817 (ADCY2)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     103084817 (ADCY2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     103084817 (ADCY2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103084817 (ADCY2)    05163 Human cytomegalovirus infection     103084817 (ADCY2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     103084817 (ADCY2) Enzymes [BR:lve01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      103084817 (ADCY2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc DUF1053 AC_N HNOBA Motif Other DBs NCBI-GeneID:  103084817 NCBI-ProteinID:  XP_007447983 UniProt:  A0A340WEH1 LinkDB All DBs Position Un AA seq 1052 aa AA seqDB search MSQQHPLIVFLLLIVMGACLALLAVFFALRLEVEDHVAFLITVPTALAIFFAIFILVCIE SVFKKLLRLFSLVIWICLVAMGYLFMCFGGTVSPWDQVSFFLFIIFVVYTMLPFNMRDAI IASVLTSSSHTVVLSVCLSAMPGAKDHVVWQILANVIIFICGNLAGAYHKHLMELALQQT YQDTCNCIKSRIKLEFEKRQQERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFH NLYVKRHTNVSILYADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGD CYYCVSGLPISLPNHAKNCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQ KWQYDVWSHDVTLANHMEAGGVPGRVHISSVTLEHLNGAYKVEEGDGDIRDPYLKQHLVK TYFVINPKGERRSPQHLFRPRSTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTE NGKISTTDVPMGQHNFQSRTLRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRI SLLFYNKILEKEYRATALPAFKYYVTCACLIFFCIFIVQILVLPKTSILGISFGAAFLSL AFILFVCFAGQLLQCSKKASASLLWLLKSSGIIAKRPWPRISLTAITTAIILTMAVFNMF FLSESEEMILPTANASNTSLPALYSQVAMLRAQNLFFLPYFIYSCILGLISCSVFLRVNY ELKMLIMMVALVGYNTIFLHTHAHLLDDYSQVLFERPGIWKDLKTMGSVSLFIFFITLLV LGRQNEYYCRLDFLWKNKFKKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEDLY HQSYDCVCVMFASIPDFKEFYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIK TIGSTYMAATGLSAVPSQEHSQEPERQYMHIGTMVEFAFALVGKLDAINKHSFNDFKLRV GINHGPVIAGVIGAQKPQYDIWGNTVNVASRMDSTGVLDKIQVTEETSLILQTLGYTCTC RGIINVKGKGDLKTYFVNTEMSRSLSQSNLAS NT seq 3159 nt NT seq  +upstreamnt  +downstreamnt atgagccagcagcacccgctcatcgtcttcctgcttctcatcgtcatgggcgcctgcctc gccctgctcgccgtcttcttcgctctccggctggaagttgaagaccacgtggcattttta ataacagttccgactgccctggcgattttctttgctatcttcatcctcgtgtgcatcgag tcagtgtttaagaagctactccgccttttttctttggtgatatggatttgtctcgtggcc atgggctacttgttcatgtgttttggaggcaccgtgtctccctgggaccaggtgtcattc ttcctcttcatcatcttcgtggtgtacaccatgctgcccttcaacatgcgagatgccatc atcgccagtgtccttacctcctcttcccacaccgtcgtgctgagtgtctgcctgtctgca atgccgggggccaaggaccacgtggtctggcagatcctggccaatgtgatcatcttcatc tgcgggaacctggccggggcgtaccataagcacctcatggaactcgctctgcagcagacg tatcaggacacttgcaattgcatcaagtcccggatcaagttggaatttgaaaagcgtcag caggagcggcttctgctgtccctgctgccagcgcacatagccatggagatgaaagccgag atcatccagaggctgcagggccccaaagccggccaaatggaaaacaccaacaactttcac aacctgtacgtcaagcggcacaccaacgtcagtatcctctatgcggacattgttgggttc acccgtctggccagtgactgctccccaggagaactggtccacatgctgaatgaactcttt ggaaaatttgatcaaattgcaaaggagaatgaatgcatgagaataaaaattctaggagac tgctactactgtgtttccggactccctatctctctccctaaccatgccaagaattgtgtg aaaatgggactggatatgtgtgaagccataaagaaagtgagggacgccactggagtggac atcaacatgcgcgtaggagtgcattctgggaacgtcctctgcggcgtgattgggctgcag aagtggcagtacgacgtatggtcccatgacgttaccctggccaaccacatggaagctgga ggggtccctggacgtgttcacatttcttccgtcacactggaacacttgaatggggcttat aaagtggaggaaggagatggtgacatcagagacccatatttaaagcagcacttggtgaag acctactttgtaatcaaccccaagggagaacgacggagcccccagcacctcttcagacct cgatccaccctcgatggagccaagatgagggcttccgtccgcatgacccggtacctggag tcctggggggcggccaagccctttgcacacctgcatcacagagacagcatgaccacggag aacggcaagatcagcaccacggatgtaccaatgggtcagcataattttcaaagtcgcacc ttaagaaccaagtcacaaaagaaaagatttgaagaggaattaaatgaaaggatgattcaa gcaattgatggaatcaatgcacaaaagcaatggctcaagtctgaagacattcagagaatc tcattgcttttctacaataaaatactagaaaaagaataccgagccactgcgctgccagcc ttcaagtattacgtgacctgcgcctgcctcatattcttctgtatcttcatcgtgcagatc ctggtcttacccaaaacatccattctcgggatttcctttggagctgcatttctctcgctt gcctttatccttttcgtctgctttgctggacagcttttgcaatgcagcaaaaaagcatcc gcctctctcctgtggcttttaaagtcgtcgggcatcatcgccaagcgcccctggcctcgg atctccctgacagccatcaccacagccatcatactaaccatggccgtgttcaacatgttt ttcctgagcgagtcagaggagatgattcttccaactgccaatgcgtcaaacacaagtctt cctgccttatatagtcaggtagcaatgctgcgtgcgcaaaatttgtttttcctgccgtac tttatatacagctgcatcctgggattgatatcctgttcggttttcctgcgcgtgaattat gagctaaagatgctgatcatgatggtggcattggtgggctacaacaccatctttctccac actcacgcccacctcctggatgactacagccaggtcttatttgagagaccaggcatttgg aaagacctaaagaccatgggctcagtgtctctctttatatttttcatcacactgcttgtt ctgggcagacagaatgaatattactgtaggttagacttcttatggaagaacaagttcaaa aaagagcgagaggagatagaaaccatggagaacttgaaccgcgtgctgctggagaacgtg ctccctgcacacgtggctgagcacttcctggccaggagcctgaagaatgaggatttatac caccagtcctatgactgtgtctgcgtcatgtttgcctccattccggatttcaaagaattc tatacagaatcggatgtgaacaaggagggcttggaatgccttcggctcctaaacgagatc attgccgactttgacgatctgctgtccaagccaaagttcagtggagttgaaaagatcaag accatcggcagcacgtacatggcggcgacgggtctgagtgccgtgcccagccaggagcac tcccaggagcctgagaggcagtacatgcacattggcaccatggtggagtttgcattcgcc ttggtggggaaactggacgccatcaacaagcactccttcaacgacttcaagttacgagta ggtattaaccatggccctgtaatagccggtgtgattggagctcagaagccacagtacgat atctggggcaacaccgtaaatgtggccagtaggatggacagcaccggcgtcctggacaaa atccaggttactgaggagacgagcctcattctgcagaccctggggtacacgtgcacatgt cgaggaataatcaacgtgaaaggaaagggggacctgaagacgtactttgtgaacacagag atgtcacggtccctttcccagagcaacctggcatcctga

Lipotes vexillifer (Yangtze River dolphin): 103085845 Help Entry 103085845         CDS       T03090                                  Gene name ADCY8 Definition (RefSeq) adenylate cyclase 8   KO K08048   adenylate cyclase 8 [EC:4.6.1.1] Organism lve  Lipotes vexillifer (Yangtze River dolphin) Pathway lve00230   Purine metabolism lve01100   Metabolic pathways lve01522   Endocrine resistance lve04015   Rap1 signaling pathway lve04020   Calcium signaling pathway lve04022   cGMP-PKG signaling pathway lve04024   cAMP signaling pathway lve04062   Chemokine signaling pathway lve04072   Phospholipase D signaling pathway lve04114   Oocyte meiosis lve04211   Longevity regulating pathway lve04213   Longevity regulating pathway - multiple species lve04261   Adrenergic signaling in cardiomyocytes lve04270   Vascular smooth muscle contraction lve04371   Apelin signaling pathway lve04540   Gap junction lve04611   Platelet activation lve04713   Circadian entrainment lve04714   Thermogenesis lve04720   Long-term potentiation lve04723   Retrograde endocannabinoid signaling lve04724   Glutamatergic synapse lve04725   Cholinergic synapse lve04727   GABAergic synapse lve04742   Taste transduction lve04750   Inflammatory mediator regulation of TRP channels lve04911   Insulin secretion lve04912   GnRH signaling pathway lve04913   Ovarian steroidogenesis lve04914   Progesterone-mediated oocyte maturation lve04915   Estrogen signaling pathway lve04916   Melanogenesis lve04918   Thyroid hormone synthesis lve04921   Oxytocin signaling pathway lve04923   Regulation of lipolysis in adipocytes lve04925   Aldosterone synthesis and secretion lve04926   Relaxin signaling pathway lve04927   Cortisol synthesis and secretion lve04928   Parathyroid hormone synthesis, secretion and action lve04934   Cushing syndrome lve04935   Growth hormone synthesis, secretion and action lve04970   Salivary secretion lve04971   Gastric acid secretion lve04972   Pancreatic secretion lve04976   Bile secretion lve05032   Morphine addiction lve05163   Human cytomegalovirus infection lve05166   Human T-cell leukemia virus 1 infection lve05200   Pathways in cancer lve05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lve00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     103085845 (ADCY8)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103085845 (ADCY8)    04371 Apelin signaling pathway     103085845 (ADCY8)    04020 Calcium signaling pathway     103085845 (ADCY8)    04072 Phospholipase D signaling pathway     103085845 (ADCY8)    04024 cAMP signaling pathway     103085845 (ADCY8)    04022 cGMP-PKG signaling pathway     103085845 (ADCY8)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     103085845 (ADCY8)   09144 Cellular community - eukaryotes    04540 Gap junction     103085845 (ADCY8)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103085845 (ADCY8)    04062 Chemokine signaling pathway     103085845 (ADCY8)   09152 Endocrine system    04911 Insulin secretion     103085845 (ADCY8)    04923 Regulation of lipolysis in adipocytes     103085845 (ADCY8)    04912 GnRH signaling pathway     103085845 (ADCY8)    04913 Ovarian steroidogenesis     103085845 (ADCY8)    04915 Estrogen signaling pathway     103085845 (ADCY8)    04914 Progesterone-mediated oocyte maturation     103085845 (ADCY8)    04921 Oxytocin signaling pathway     103085845 (ADCY8)    04926 Relaxin signaling pathway     103085845 (ADCY8)    04935 Growth hormone synthesis, secretion and action     103085845 (ADCY8)    04918 Thyroid hormone synthesis     103085845 (ADCY8)    04928 Parathyroid hormone synthesis, secretion and action     103085845 (ADCY8)    04916 Melanogenesis     103085845 (ADCY8)    04925 Aldosterone synthesis and secretion     103085845 (ADCY8)    04927 Cortisol synthesis and secretion     103085845 (ADCY8)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     103085845 (ADCY8)    04270 Vascular smooth muscle contraction     103085845 (ADCY8)   09154 Digestive system    04970 Salivary secretion     103085845 (ADCY8)    04971 Gastric acid secretion     103085845 (ADCY8)    04972 Pancreatic secretion     103085845 (ADCY8)    04976 Bile secretion     103085845 (ADCY8)   09156 Nervous system    04724 Glutamatergic synapse     103085845 (ADCY8)    04727 GABAergic synapse     103085845 (ADCY8)    04725 Cholinergic synapse     103085845 (ADCY8)    04720 Long-term potentiation     103085845 (ADCY8)    04723 Retrograde endocannabinoid signaling     103085845 (ADCY8)   09157 Sensory system    04742 Taste transduction     103085845 (ADCY8)    04750 Inflammatory mediator regulation of TRP channels     103085845 (ADCY8)   09149 Aging    04211 Longevity regulating pathway     103085845 (ADCY8)    04213 Longevity regulating pathway - multiple species     103085845 (ADCY8)   09159 Environmental adaptation    04713 Circadian entrainment     103085845 (ADCY8)    04714 Thermogenesis     103085845 (ADCY8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103085845 (ADCY8)   09165 Substance dependence    05032 Morphine addiction     103085845 (ADCY8)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     103085845 (ADCY8)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     103085845 (ADCY8)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103085845 (ADCY8)    05163 Human cytomegalovirus infection     103085845 (ADCY8)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     103085845 (ADCY8) Enzymes [BR:lve01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      103085845 (ADCY8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N DUF1053 TBK1_ULD Motif Other DBs NCBI-GeneID:  103085845 NCBI-ProteinID:  XP_007448050 UniProt:  A0A340WM11 LinkDB All DBs Position Un AA seq 1250 aa AA seqDB search MELSDVRCLSGSEDLYTIHPTPPAGDGGSASRPPRLLWQTAVRHITEQRFVHGHRGSGGG SGSSSKASDPVGGGPNHHASQLAGDSALPLYALGPGERAHSPGCTKVFPERSGSGGGGGS GGAGDLGFLHLDCAPSNSDFFLKGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKS EVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTY LQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTIFATYSMLPLPLTWAILAGLGTSF LQVVLQGVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARL RLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVK GFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHC CVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLE SGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLSLPEDI VKESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQ SGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFI VLLFITAIQSLLPSSRVMPMAIQFSILIMLHSALVLITTAEDYKCLPLVLRKTCCWINET YLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGV LAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDNLNHSGEDFLGTKEAS LLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVAR HFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDEL LGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWEHLCALADFSLALTESIQEINKHS FNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILK DQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQ SLNRQRQKQLLNENNNTGIIKGHYNRRTLLTPSGPEPGAQVEGTDKSELP NT seq 3753 nt NT seq  +upstreamnt  +downstreamnt atggagctctccgatgtgcgctgccttagcggcagcgaggacctctacaccatccacccg acgcccccggccggcgacggcgggagcgcctcccggccgccgcggctgctgtggcaaacg gcggtgcggcacatcaccgagcagcgcttcgtacacgggcatcggggcagcggcggcggg agcggaagctccagcaaagcctcggaccctgtaggcggcggccccaaccaccacgcgtcg cagctggccggcgactcggcgctgcccctctacgcgctgggccccggggagagagctcac agccccggctgcaccaaagtcttcccggaacgcagcggcagcggcggcggcggcggcagc gggggcgcgggcgacctgggcttcctgcacctcgactgcgccccgagcaactcggatttc ttcctcaaggggggctatagctaccgaggggtcattttccccaccctgcgcaactccttc aagtcccgggatctggagcgcctctaccagcgctatttcctgggccagaggcgcaaatcg gaggtggtgatgaacgtgctggacgtgctgaccaaactcaccctcttggttctccacttg agcctggcctcggcccccatggacccgctcaagggcatcctgctgggcttcttcacgggc atagaggtggtgatctgcgccttggtggtggtcaggaaggacaccacctcgcacacctac ctgcagtacagcggcgtggtcacctgggtggccatgaccacccagatcttagcagcaggt ctgggctatgggctcctgggagacggcattggctacgtgctcttcacaatcttcgccacc tacagcatgctgccgctgccgctcacctgggccatcctggctggcctgggcacgtcgttc ctgcaggtggtcctccaaggggtcatccccaggctggcggtcatttctatcaaccaggtt gtggcccaggcagtgttattcatgtgtatgaacacagctggaatctttatcagttacctg tcagaccgggcccagcgccaagccttcctggagacgcggaggtgtgtggaagccaggctg cgcctagagacggaaaaccaaagacaggagcggcttgtgctgtctgtgctccctcggttt gtcgtcctggagatgatcaatgacatgaccaacgtggaagacgagcacctgcagcatcaa ttccaccggatctacatccaccgctacgagaatgtcagtattctttttgcagatgtcaaa ggatttaccaacctctccacgaccttgtctgcccaggagctggtcaggatgctcaacgag ctctttgccagatttgatcgactggcccatgagcatcactgccttcgcattaaaatcctg ggagactgctactactgcgtttcgggacttcctgagccccgccaggaccacgcccactgc tgcgttgaaatgggcctcagcatgatcaaaaccatcaggtatgtgcggtcaaggacgaag catgatgttgacatgcggattggaatccactcgggctcagtgctatgtggcgtgttgggt ctacggaagtggcagtttgatgtctggtcttgggatgtggatattgcaaacaaacttgaa tctggaggaatccctgggaggattcacatttccaaagccacgctggactgcctcaacggt gactataatgtggaagagggtcatggtaaagagaggaacgaattcttgaggaagcataat atagagacctatttaattaagcagcctgaggagagtctgctgtctttgcctgaagacatc gtcaaggaatctgtgagctcctcagacaggagaaacagtggggcgacattcacagaagga tcctggagccccgaactgccctttgataacatagtggggaaacagaacactctggctgcc ctaacaagaaattcaataaatctacttccaaaccatcttgcacaagctttgcatgtccag tctgggcctgaggaaattaacaagagaatagaacataccatcgacttgcggagtggcgat aaattgagaagagagcatatcaagccattctcactgatgtttaaagactccagcctggag cacaagtattctcaaatgagggacgaagtattcaaatcaaacttggtctgtgcgtttatc gttcttctatttatcacggcaatacaaagtttgcttccttcttcaagggtgatgccaatg gccatccagttttccatcctgattatgctgcactcggctttggtcctcatcaccacagcg gaggattataagtgtttgcccctggtcctccggaaaacttgctgttggattaacgagacc tatttggccaggaatgtcatcatctttgcgtccatcttgattaatttcctgggcgccatc ctaaatatcctgtggtgtgattttgacaagtcgatacccttgaagaacctgactttcaat tcctcagctgtgtttacagatatctgctcctacccagagtactttgtcttcacgggggtg ttggccatggtgacctgtgcggttttcctccgacttaactctgtcctgaagctggctgtg ctgctgattatgattgccatctatgccctgctgaccgagaccatctatgcaggactcttt ctgcgctatgacaacctgaatcacagtggagaagatttcctggggaccaaggaggcgtca ctgctgctgatggccatgttcctcctcgctgtcttctaccatggacagcagctggagtac acagcacgcctggacttcctctggcgagttcaggccaaagaggagatcaacgagatgaag gagctgagggaacacaatgagaacatgctccggaacatcctgcccagtcacgtggcccgc cacttcctagagaaggaccgcgacaatgaggagctgtattctcaatcctatgatgccgtt ggggtgatgtttgcctccatcccagggtttgcagacttctactctcagactgaaatgaac aaccaaggagtggaatgcctacgcctgctgaatgagatcattgccgacttcgatgagctg cttggtgaagaccggtttcaagacattgaaaagattaagaccattggcagcacctacatg gccgtgtcaggcctgtcacctgaaaaacagcaatgtgaagataagtgggaacatttgtgt gccctggccgacttctctctcgccctgacggaaagcatacaggagatcaacaagcattct ttcaacaattttgagctccggattggcatcagtcacggctcagtggtagctggcgttatc ggcgctaagaaaccacaatacgacatttggggcaaaaccgtgaacctggcaagtcgaatg gacagcacgggagtcagcggcagaatccaggtcccagaggagacctatctcatcctgaag gaccagggctttgcctttgactaccgaggggagatctatgtgaagggcatcagtgaacag gaaggaaaaatcaaaacgtactttctcctgggaagagtccaacccaacccattcatcctg ccgccgagaagactgcccgggcagtactccttggccgcggtcgtcctgggcctcgtccag tccctcaacaggcaaaggcagaagcagctgctgaatgagaacaacaacacgggcatcatc aagggccattacaaccggcggactttgctgacacccagtgggcctgagccgggagcccaa gtcgaaggcaccgacaagtccgagttgccatag

Lipotes vexillifer (Yangtze River dolphin): 103091169 Help Entry 103091169         CDS       T03090                                  Gene name ADCY5 Definition (RefSeq) adenylate cyclase 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism lve  Lipotes vexillifer (Yangtze River dolphin) Pathway lve00230   Purine metabolism lve01100   Metabolic pathways lve01522   Endocrine resistance lve04015   Rap1 signaling pathway lve04022   cGMP-PKG signaling pathway lve04024   cAMP signaling pathway lve04062   Chemokine signaling pathway lve04072   Phospholipase D signaling pathway lve04114   Oocyte meiosis lve04211   Longevity regulating pathway lve04213   Longevity regulating pathway - multiple species lve04261   Adrenergic signaling in cardiomyocytes lve04270   Vascular smooth muscle contraction lve04371   Apelin signaling pathway lve04540   Gap junction lve04611   Platelet activation lve04713   Circadian entrainment lve04714   Thermogenesis lve04723   Retrograde endocannabinoid signaling lve04724   Glutamatergic synapse lve04725   Cholinergic synapse lve04726   Serotonergic synapse lve04727   GABAergic synapse lve04728   Dopaminergic synapse lve04750   Inflammatory mediator regulation of TRP channels lve04911   Insulin secretion lve04912   GnRH signaling pathway lve04913   Ovarian steroidogenesis lve04914   Progesterone-mediated oocyte maturation lve04915   Estrogen signaling pathway lve04916   Melanogenesis lve04918   Thyroid hormone synthesis lve04921   Oxytocin signaling pathway lve04923   Regulation of lipolysis in adipocytes lve04924   Renin secretion lve04925   Aldosterone synthesis and secretion lve04926   Relaxin signaling pathway lve04927   Cortisol synthesis and secretion lve04928   Parathyroid hormone synthesis, secretion and action lve04934   Cushing syndrome lve04935   Growth hormone synthesis, secretion and action lve04970   Salivary secretion lve04971   Gastric acid secretion lve04972   Pancreatic secretion lve04976   Bile secretion lve05012   Parkinson disease lve05030   Cocaine addiction lve05031   Amphetamine addiction lve05032   Morphine addiction lve05034   Alcoholism lve05163   Human cytomegalovirus infection lve05166   Human T-cell leukemia virus 1 infection lve05200   Pathways in cancer lve05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lve00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     103091169 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103091169 (ADCY5)    04371 Apelin signaling pathway     103091169 (ADCY5)    04072 Phospholipase D signaling pathway     103091169 (ADCY5)    04024 cAMP signaling pathway     103091169 (ADCY5)    04022 cGMP-PKG signaling pathway     103091169 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     103091169 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     103091169 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103091169 (ADCY5)    04062 Chemokine signaling pathway     103091169 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     103091169 (ADCY5)    04923 Regulation of lipolysis in adipocytes     103091169 (ADCY5)    04912 GnRH signaling pathway     103091169 (ADCY5)    04913 Ovarian steroidogenesis     103091169 (ADCY5)    04915 Estrogen signaling pathway     103091169 (ADCY5)    04914 Progesterone-mediated oocyte maturation     103091169 (ADCY5)    04921 Oxytocin signaling pathway     103091169 (ADCY5)    04926 Relaxin signaling pathway     103091169 (ADCY5)    04935 Growth hormone synthesis, secretion and action     103091169 (ADCY5)    04918 Thyroid hormone synthesis     103091169 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     103091169 (ADCY5)    04916 Melanogenesis     103091169 (ADCY5)    04924 Renin secretion     103091169 (ADCY5)    04925 Aldosterone synthesis and secretion     103091169 (ADCY5)    04927 Cortisol synthesis and secretion     103091169 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     103091169 (ADCY5)    04270 Vascular smooth muscle contraction     103091169 (ADCY5)   09154 Digestive system    04970 Salivary secretion     103091169 (ADCY5)    04971 Gastric acid secretion     103091169 (ADCY5)    04972 Pancreatic secretion     103091169 (ADCY5)    04976 Bile secretion     103091169 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     103091169 (ADCY5)    04727 GABAergic synapse     103091169 (ADCY5)    04725 Cholinergic synapse     103091169 (ADCY5)    04728 Dopaminergic synapse     103091169 (ADCY5)    04726 Serotonergic synapse     103091169 (ADCY5)    04723 Retrograde endocannabinoid signaling     103091169 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     103091169 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     103091169 (ADCY5)    04213 Longevity regulating pathway - multiple species     103091169 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     103091169 (ADCY5)    04714 Thermogenesis     103091169 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103091169 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     103091169 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     103091169 (ADCY5)    05031 Amphetamine addiction     103091169 (ADCY5)    05032 Morphine addiction     103091169 (ADCY5)    05034 Alcoholism     103091169 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     103091169 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     103091169 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103091169 (ADCY5)    05163 Human cytomegalovirus infection     103091169 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     103091169 (ADCY5) Enzymes [BR:lve01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      103091169 (ADCY5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc DUF1053 HNOBA TBK1_ULD Motif Other DBs NCBI-GeneID:  103091169 NCBI-ProteinID:  XP_007449752 UniProt:  A0A340WQ40 LinkDB All DBs Position Un AA seq 1263 aa AA seqDB search MSSSKSVSPPGYAAQTAAAPASRGGPEHRSAWGEADSRANGYPHAPGGSARGSTKKPGGT VTPQQQQQQRLASRWRSDDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQ RRGAAGGGSTRAPPAGGGXXXXXXXAPAAAGGTEVRPRSVELGLEERRGKGRAADELEAG AVEEDEGSGDGGSLAGSGAGPGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLN QSSLTMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILVMAVLCNRAAFHQDHM GLACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLS ALHLAIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQAR LHSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGF TSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCV EMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAG GKAGRIHITKATLNYLNGDYEVEPGGGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAK MNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDE FLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFV QITIVPHSVFMLSFYLTCFLLLTVVVFVSVIYSCVKLFPAPLQRLSRKIVRSKMNSTLVG VFTITLVFLSAFVNMFTCNSKDLIGCLADEHNISASQVSTCHVVESAGNYSLGDERGFCG SPWPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAVELIYVLVVEVPGVTLFDNA DLLVTANAVDFNNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLW KLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIA NFSEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDS TYDKVGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDI WGNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGP PPS NT seq 3792 nt NT seq  +upstreamnt  +downstreamnt atgtccagctccaaaagcgtgagccccccgggctacgcggcgcagacagcggcggcgccg gcgtcccggggaggcccggaacaccgctcggcgtggggcgaggccgactcccgcgccaat ggctacccccacgcccccgggggttcggcccgcggctccaccaagaaacccggggggacg gtgaccccgcagcagcagcagcagcagcgcctggccagccgctggcgcagcgacgacgac gacgatcctccgctgagtggcgatgaccccctggctgggggcttcggcttcagtttccgt tccaagtcggcctggcaggagcgcggcggcgacgactgcggtcgcggcagccggcggcag cggcggggcgcggccggcgggggcagcacccgggcgccccctgcgggcggcggnnnnnnn nnnnnnnnnnnnnnngcgcccgccgcagctggcgggacggaggtgcgcccccgttctgtg gagctgggtctggaggagcggcggggcaagggccgcgcggccgacgagctggaggccggc gccgtcgaggaagacgagggttccggagatggcggcagcttggcaggctcaggcgcgggc cctggcgcggtgctgtcgctgggcgcctgctgcctggcgctgctgcagatattccgctcg aagaagttcccgtcggacaagctggagcggctgtaccagcgctacttcttccgtctgaac cagagcagcctcactatgctcatggctgtgctggtgctcgtgtgcctcgtcatgttggcc ttccacgcggcacggcccccgctgcagctgccctacctggccgtgctggcggctgcagtg ggtgtgatcctcgtcatggccgtgctctgcaaccgcgccgccttccaccaggaccacatg ggcctggcctgctacgcgctcatcgccgtggtgctggctgtccaggtggtgggcctgctg ctgcctcagccgcgcagcgcctccgagggcatctggtggactgtgttcttcatctatacc atctacacgctgctgcccgtgcgcatgcgggccgcggtactcagcggggtgctcctgtct gccctccacctggccatcgccctgcgcaccaacgcccaggaccagttcctgctcaagcag ctcgtctccaatgtcctcattttctcctgcaccaacatcgtgggcgtctgcacccactac ccggctgaggtctcccagagacaggccttccaggagacccgggagtgcatccaggctcgg ctgcactcgcagcgggagaaccagcagcaggagcggctcctgctgtctgtccttccccgt cacgttgccatggagatgaaagcagacatcaatgccaaacaggaagatatgatgttccat aaaatttacatccagaaacatgacaacgtgagcatcctgtttgcggacatcgagggcttc accagcctggcgtcccagtgcactgcccaggagcttgtcatgaccctcaacgagctcttc gcccgcttcgacaagctggctgcagagaatcactgtttacgtattaagatcctgggagat tgttattactgcgtctcagggctgcctgaagccagggctgaccatgcccactgctgcgtg gagatgggcatggacatgattgaggccatctcgctggtccgggaggtgacaggtgtcaac gtgaacatgcgtgtgggaatccacagcggtcgagtgcactgtggcgtccttggcctcagg aagtggcagttcgacgtctggtctaacgacgtcacgctggccaaccacatggaggctgga ggcaaggcgggacgcatccacatcaccaaggccacactcaactacctgaatggcgactac gaagtggagccgggcggtgggggcgagcgcaacgcctacctcaaagagcacagtatcgag accttcctcatcctgcgctgcacccagaagcggaaagaagagaaggccatgattgccaag atgaatcgtcagagaaccaactcgatcgggcacaacccaccacactggggggccgagcgc cccttctacaaccacctgggtggcaaccaggtgtccaaggagatgaaacggatgggcttt gaagatcccaaggacaagaacgcccaggaaagtgcgaaccccgaggatgaagtggatgaa tttctgggccgtgccattgacgccaggagcatcgacaggctacgatctgagcatgttcgc aagttcctcttgaccttcagggagcctgacttagagaagaagtactccaagcaggtggat gaccgattcggtgcctacgtggcatgtgcctcgctcgtcttcctcttcatctgctttgtc cagatcaccattgtgccccactccgtgttcatgttgagtttctacctgacctgtttcctg ctgctgaccgtggtggtatttgtttccgtgatctactcctgtgtgaagctcttcccggcc ccgctgcagaggctctccaggaagatcgtgcggtccaagatgaacagcaccctggtgggc gtgttcaccatcaccctggtgttcctgtcggcttttgtcaacatgttcacgtgcaactcc aaggacctgattggctgcctggcggacgaacacaacatcagtgccagccaggtcagcacg tgccacgtggtggagtcagccggcaactacagcctgggtgatgagcggggcttctgcggc agcccctggcccaactgcaacttccccgagtacttcacctacagcgtgctgctcagcctg ctggcctgctccgtgttcctgcagatcagctgcatcgggaagctggtgctcatgctggcc gtcgaactcatctacgtgcttgtcgttgaggtgcccggagtcacgctctttgacaatgcc gacctactggtcacagccaacgccgtagacttcaacaacaacgggacctcccagtgccct gagcacgcgaccaaggtggcgctgaaggtggtgacgcccatcatcatctccgtctttgtg ctggccctgtacctgcacgcccagcaggtggagtccaccgcccgcctcgacttcctctgg aaactgcaggccaccgaggagaaggaggagatggaggagctgcaggcctacaaccggcgg ctgctgcacaacatcctgcccaaggacgtagccgcgcacttcctggcccgcgagcggcgc aatgatgagctctactatcagtcgtgtgagtgcgtggccgtcatgttcgcctccatcgcc aacttctccgagttctacgtggagctggaggccaacaacgagggcgtcgagtgcctgagg ctgctcaacgagatcatcgctgactttgacgagatcatcagtgaggaccggttccggcag ctggaaaagatcaagaccatcggcagcacctacatggccgcctcgggcctcaacgactcc acctatgacaaggtgggcaagacgcacatcaaagctctggctgacttcgccatgaagctg atggaccaaatgaagtacatcaacgagcactccttcaacaacttccagatgaagattggg ctcaatatcggccccgtagtggctggggtgattggggcccgcaaacctcagtacgacatc tggggcaacacagtgaacgtggccagccgcatggacagcaccggcgtgcccgaccgcatc caggtcaccacagacatgtaccaggtgctggccgccaacacgtaccagctggagtgccgg ggtgtggtcaaggtcaagggcaaaggcgagatgatgacatacttcctcaacggagggccc ccgcccagttag

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