Lipotes vexillifer (Yangtze River dolphin): 103071962
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Entry
103071962 CDS
T03090
Gene name
EGFR
Definition
(RefSeq) epidermal growth factor receptor
KO
K04361
epidermal growth factor receptor [EC:
2.7.10.1
]
Organism
lve
Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve01521
EGFR tyrosine kinase inhibitor resistance
lve01522
Endocrine resistance
lve04010
MAPK signaling pathway
lve04012
ErbB signaling pathway
lve04014
Ras signaling pathway
lve04015
Rap1 signaling pathway
lve04020
Calcium signaling pathway
lve04066
HIF-1 signaling pathway
lve04068
FoxO signaling pathway
lve04072
Phospholipase D signaling pathway
lve04144
Endocytosis
lve04151
PI3K-Akt signaling pathway
lve04510
Focal adhesion
lve04520
Adherens junction
lve04540
Gap junction
lve04630
JAK-STAT signaling pathway
lve04810
Regulation of actin cytoskeleton
lve04912
GnRH signaling pathway
lve04915
Estrogen signaling pathway
lve04921
Oxytocin signaling pathway
lve04926
Relaxin signaling pathway
lve04928
Parathyroid hormone synthesis, secretion and action
lve04934
Cushing syndrome
lve05160
Hepatitis C
lve05163
Human cytomegalovirus infection
lve05165
Human papillomavirus infection
lve05171
Coronavirus disease - COVID-19
lve05200
Pathways in cancer
lve05205
Proteoglycans in cancer
lve05206
MicroRNAs in cancer
lve05210
Colorectal cancer
lve05212
Pancreatic cancer
lve05213
Endometrial cancer
lve05214
Glioma
lve05215
Prostate cancer
lve05218
Melanoma
lve05219
Bladder cancer
lve05223
Non-small cell lung cancer
lve05224
Breast cancer
lve05225
Hepatocellular carcinoma
lve05226
Gastric cancer
lve05230
Central carbon metabolism in cancer
lve05231
Choline metabolism in cancer
lve05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
lve00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103071962 (EGFR)
04012 ErbB signaling pathway
103071962 (EGFR)
04014 Ras signaling pathway
103071962 (EGFR)
04015 Rap1 signaling pathway
103071962 (EGFR)
04630 JAK-STAT signaling pathway
103071962 (EGFR)
04066 HIF-1 signaling pathway
103071962 (EGFR)
04068 FoxO signaling pathway
103071962 (EGFR)
04020 Calcium signaling pathway
103071962 (EGFR)
04072 Phospholipase D signaling pathway
103071962 (EGFR)
04151 PI3K-Akt signaling pathway
103071962 (EGFR)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
103071962 (EGFR)
09144 Cellular community - eukaryotes
04510 Focal adhesion
103071962 (EGFR)
04520 Adherens junction
103071962 (EGFR)
04540 Gap junction
103071962 (EGFR)
09142 Cell motility
04810 Regulation of actin cytoskeleton
103071962 (EGFR)
09150 Organismal Systems
09152 Endocrine system
04912 GnRH signaling pathway
103071962 (EGFR)
04915 Estrogen signaling pathway
103071962 (EGFR)
04921 Oxytocin signaling pathway
103071962 (EGFR)
04926 Relaxin signaling pathway
103071962 (EGFR)
04928 Parathyroid hormone synthesis, secretion and action
103071962 (EGFR)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103071962 (EGFR)
05206 MicroRNAs in cancer
103071962 (EGFR)
05205 Proteoglycans in cancer
103071962 (EGFR)
05230 Central carbon metabolism in cancer
103071962 (EGFR)
05231 Choline metabolism in cancer
103071962 (EGFR)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
103071962 (EGFR)
09162 Cancer: specific types
05210 Colorectal cancer
103071962 (EGFR)
05212 Pancreatic cancer
103071962 (EGFR)
05225 Hepatocellular carcinoma
103071962 (EGFR)
05226 Gastric cancer
103071962 (EGFR)
05214 Glioma
103071962 (EGFR)
05218 Melanoma
103071962 (EGFR)
05219 Bladder cancer
103071962 (EGFR)
05215 Prostate cancer
103071962 (EGFR)
05213 Endometrial cancer
103071962 (EGFR)
05224 Breast cancer
103071962 (EGFR)
05223 Non-small cell lung cancer
103071962 (EGFR)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
103071962 (EGFR)
09172 Infectious disease: viral
05160 Hepatitis C
103071962 (EGFR)
05171 Coronavirus disease - COVID-19
103071962 (EGFR)
05163 Human cytomegalovirus infection
103071962 (EGFR)
05165 Human papillomavirus infection
103071962 (EGFR)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103071962 (EGFR)
01522 Endocrine resistance
103071962 (EGFR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lve01001
]
103071962 (EGFR)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
lve04147
]
103071962 (EGFR)
Enzymes [BR:
lve01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
103071962 (EGFR)
Protein kinases [BR:
lve01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
103071962 (EGFR)
Exosome [BR:
lve04147
]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
103071962 (EGFR)
Exosomal proteins of pancreatic cancer cells
103071962 (EGFR)
Exosomal proteins of bladder cancer cells
103071962 (EGFR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
APH
Kinase-like
Borrelia_P83
Kdo
Motif
Other DBs
NCBI-GeneID:
103071962
NCBI-ProteinID:
XP_007463741
UniProt:
A0A340XQY3
LinkDB
All DBs
Position
Un
AA seq
1209 aa
AA seq
DB search
MRRSEAGRAVLLALLAAHFQASPALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEV
VLGNLEITYMQSSYNLSFLKTIQEVAGYVLIALNTVEKIPLEKLQIIRGNVLYENTHALA
VLSNYGANKTGLRELPMRNLQEILQGAVRFSNNPVLCNMDTVQWRDIVNTDFLSNMSTEF
QSQLSRCPKCDPVCLNGSCWGAGKENCQKLTKVICAQQCSGRCRGRSPSDCCHSQCAAGC
TGPRESDCLVCRRFRDGATCKDTCPPLMLYDPTTYEMKVNPLGKYSFGATCVRKCPRNYV
VTDHGSCVRACSSDSQEVEEDGVRKCKKCDGPCGKVCNGIGIGEFKDTLSINATNIKHFR
NCTSISGDLHILPVAFKGDSFTRTPPLDPKELDILKTVKEITGFLLIQAWPANRTGLHAF
ENLEIIRGRTKQHGQFSLAVVGLDIMSLGLRSLKEISDGDVIISGNRKLCYADTINWKKL
FGTSSQKTKIINNRSEKECKAMGHVCNPLCSSEGCWGPKPKDCVSCRNFSRGKECVEKCN
VLKGEPREFVENSECVQCHPECLPQAMNVTCTGHGPGSCVKCAHNIDGPHCVKTCPAGVT
GENSTLIWKFADANHVCHLCHPSCTYGCAGPGLEGCAVSGPRIPSIATGIVGALLLALVL
ALGVGLFLRRRRIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETELKKVKVLGS
GAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGI
CLTSTVQLITQLMPFGCLLDYVREHKDNIGSQHLLNWCVQIAKGMNYLEDRRLVHRDLAA
RNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSY
GVTVWELMTFGSKPYDGIPASEISTVLEKGERLPQPPICTIDVYMIMVKCWMIDADSRPK
FRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSSFYRALVDEEDMQDVVDADEYLIPQ
QGFFHSPATSRTPLLSSLSATSNTPTVACGDRNGQSYPLPEDSFLQRYSSDPTGTLTEDS
IDDAFLPAPEYINQSIPKRPAGSVQNPVYHNQPLNPAPGRDPHYQNSHSNAVDSPEYLNT
TRPACTNGVLDGPALWAQKGGHQISLDNPDYQQAFFPKEAKSNGIFKGSAAENAEYLRVA
PAGSDLTGA
NT seq
3630 nt
NT seq
+upstream
nt +downstream
nt
atgcgacgctccgaagcgggccgcgccgtgctcctggcgctgctggccgcgcacttccag
gcgagtccggcgctggaggagaagaaagtttgccaagggacaagtaacaagctcacccag
ttgggcacttttgaagaccactttctgagcctccagaggatgttcaataactgtgaggtg
gtccttgggaatttggaaataacctacatgcaaagtagttacaacctttctttcctgaag
accatccaggaggttgctggctatgtactcattgccctcaacacagtggagaagattcct
ttggaaaagctgcagatcatcagaggaaatgtgctctatgaaaacacccatgccttagcg
gtcttatccaactacggtgcaaataaaacgggactgagggagttgcccatgagaaactta
caggagatcctgcaaggcgccgtgcgattcagcaacaaccctgtcctctgcaacatggac
accgtccagtggagggacatcgtcaacaccgactttctaagcaatatgtcaactgaattt
cagagccagctgagcagatgcccaaagtgtgatccagtctgtcttaatggaagctgctgg
ggtgcggggaaggagaactgccagaaactgaccaaagtcatctgtgcccagcagtgttcc
gggcgctgccgcggcaggtcccccagcgactgctgccacagccagtgtgccgccggctgc
acagggccacgggagagtgactgcctggtctgccgcaggttccgggacggtgccacgtgc
aaggacacatgcccgccactcatgctgtacgaccccaccacctacgagatgaaagtcaac
ccactggggaagtatagcttcggcgccacctgtgtcaggaagtgcccccgtaactacgtg
gtgacggaccacggctcgtgcgtccgcgcctgcagctctgacagccaggaggtggaggag
gacggcgtccgcaagtgtaaaaagtgcgacggaccttgtggcaaagtttgtaacggaata
ggaattggtgagtttaaagatacactttccataaatgctacaaatattaaacacttcaga
aattgcacctcgatcagtggagaccttcatatcctgccagtagcatttaagggtgattcc
ttcacacgtactccacctctggacccaaaggaactggacattctaaaaactgtaaaggaa
ataacagggtttttgctgattcaggcctggcctgcaaacaggactggcctccatgctttt
gagaacctggaaatcatacgtggcaggacgaagcaacatggtcagttttctctggcggtt
gttggcctggatataatgtccttgggattacgctccctcaaggagataagtgatggagat
gtgatcatttcaggaaaccgaaagttgtgctacgcagatacaataaactggaaaaaactc
tttgggacctcaagtcagaaaaccaaaattataaacaacaggagtgaaaaagagtgcaag
gccatgggccacgtctgtaacccgctgtgctcgtcagagggctgctggggcccgaaaccc
aaagactgcgtgtcctgccgaaacttcagtcgtggcaaggagtgtgtggagaagtgcaac
gttctaaagggagagcccagggagttcgttgagaactccgagtgcgtgcagtgccatccg
gaatgcctgccccaggccatgaacgtgacctgcacgggacacggaccaggcagctgtgta
aagtgtgcccacaacatcgacggccctcactgcgtcaagacctgccctgctggagtcaca
ggagaaaacagcaccctgatctggaagtttgcagatgccaatcacgtgtgtcacctgtgc
caccccagctgcacctacggctgtgctgggccaggtcttgaaggctgtgcagtgagtggg
cccaggattccgtccatcgccaccgggatcgtgggcgccctgctgctggccctggtgctg
gccctgggggtcggcctctttctgcgcaggcgccgcatcgtccgcaagcgcacgctgcgc
cggctgctgcaggagcgcgagcttgtcgagcctctgacgcccagcggagaagctcccaac
caagctctcttgaggatcttaaaggagacggaattaaaaaaggtcaaggtgctgggctcc
ggagcattcggcacggtgtacaagggactgtggatcccagaaggcgagaaggttaaaatt
cctgtggctatcaaggaattaagagaagccacatctccaaaagccaacaaggaaattctt
gatgaagcctacgtgatggccagtgtggacaatcctcacgtgtgccgcctcctgggcatc
tgcctgacgtccacggtgcagctcatcacgcagctcatgcccttcggctgcctgctggac
tatgtccgcgagcacaaggacaacatcggctcccagcacctgctcaactggtgcgtgcag
atcgcaaagggcatgaactacctggaagaccggcgcctggtgcaccgagacctggcggcc
aggaatgtgctggtgaagacgccgcagcacgtcaagatcacggatttcgggctggccaaa
ctgctgggcgctgaggagaaagaataccatgcggaggggggcaaagtgcctatcaagtgg
atggctttggaatcaattttacaccgaatttatacccaccagagtgacgtctggagctac
ggagtcaccgtttgggagttgatgacctttgggtccaagccttacgacgggatccccgcg
agtgagatctcaaccgtcctggagaagggagaacgcctgcctcagccgcccatctgcacc
atcgacgtctacatgatcatggtcaagtgctggatgattgatgcagatagtcgcccaaag
ttccgtgagttgatcattgaattctccaagatggcccgagacccccagcgctaccttgtc
atccagggggacgagaggatgcacttgccaagccccacggactccagcttctaccgcgcc
ctggtggatgaagaggacatgcaggatgttgtggatgcggacgagtacctcatcccccag
cagggcttcttccacagccccgccacctcccggacgcccctcctcagttctctgagcgcc
accagcaacacgcccactgtggcttgcggtgatagaaacgggcagagctatcccctccct
gaagatagcttcttgcagcggtacagctccgaccccactggcaccttgaccgaggacagc
atagatgacgccttccttccagcgcccgaatacataaaccagtctattcccaaaaggccc
gcgggctctgtccagaaccccgtctatcacaatcagcctctaaacccggctccaggcaga
gaccctcactaccagaattcccacagcaatgccgtggacagccctgagtatctcaacacc
acccgtcccgcctgcaccaacggtgtgctcgacggccctgccctctgggcacagaaaggc
ggtcaccaaattagcctggacaaccctgactaccagcaggccttctttcccaaggaagcc
aagtcaaatggcatctttaagggttctgccgctgaaaatgcagaatacctaagggtagca
ccagcgggcagcgaccttaccggggcctga
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