Lipotes vexillifer (Yangtze River dolphin): 103078639 Help Entry 103078639         CDS       T03090                                  Gene name PLCB4 Definition (RefSeq) phospholipase C beta 4   KO K05858   phosphatidylinositol phospholipase C, beta [EC:3.1.4.11] Organism lve  Lipotes vexillifer (Yangtze River dolphin) Pathway lve00562   Inositol phosphate metabolism lve01100   Metabolic pathways lve04015   Rap1 signaling pathway lve04020   Calcium signaling pathway lve04022   cGMP-PKG signaling pathway lve04062   Chemokine signaling pathway lve04070   Phosphatidylinositol signaling system lve04071   Sphingolipid signaling pathway lve04072   Phospholipase D signaling pathway lve04261   Adrenergic signaling in cardiomyocytes lve04270   Vascular smooth muscle contraction lve04310   Wnt signaling pathway lve04371   Apelin signaling pathway lve04540   Gap junction lve04611   Platelet activation lve04613   Neutrophil extracellular trap formation lve04621   NOD-like receptor signaling pathway lve04713   Circadian entrainment lve04720   Long-term potentiation lve04723   Retrograde endocannabinoid signaling lve04724   Glutamatergic synapse lve04725   Cholinergic synapse lve04726   Serotonergic synapse lve04728   Dopaminergic synapse lve04730   Long-term depression lve04742   Taste transduction lve04750   Inflammatory mediator regulation of TRP channels lve04911   Insulin secretion lve04912   GnRH signaling pathway lve04915   Estrogen signaling pathway lve04916   Melanogenesis lve04918   Thyroid hormone synthesis lve04919   Thyroid hormone signaling pathway lve04921   Oxytocin signaling pathway lve04922   Glucagon signaling pathway lve04924   Renin secretion lve04925   Aldosterone synthesis and secretion lve04926   Relaxin signaling pathway lve04927   Cortisol synthesis and secretion lve04928   Parathyroid hormone synthesis, secretion and action lve04929   GnRH secretion lve04933   AGE-RAGE signaling pathway in diabetic complications lve04934   Cushing syndrome lve04935   Growth hormone synthesis, secretion and action lve04961   Endocrine and other factor-regulated calcium reabsorption lve04970   Salivary secretion lve04971   Gastric acid secretion lve04972   Pancreatic secretion lve04973   Carbohydrate digestion and absorption lve05010   Alzheimer disease lve05016   Huntington disease lve05017   Spinocerebellar ataxia lve05022   Pathways of neurodegeneration - multiple diseases lve05142   Chagas disease lve05143   African trypanosomiasis lve05146   Amoebiasis lve05163   Human cytomegalovirus infection lve05200   Pathways in cancer Module lve_M00130   Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Brite KEGG Orthology (KO) [BR:lve00001]  09100 Metabolism   09101 Carbohydrate metabolism    00562 Inositol phosphate metabolism     103078639 (PLCB4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103078639 (PLCB4)    04310 Wnt signaling pathway     103078639 (PLCB4)    04371 Apelin signaling pathway     103078639 (PLCB4)    04020 Calcium signaling pathway     103078639 (PLCB4)    04070 Phosphatidylinositol signaling system     103078639 (PLCB4)    04072 Phospholipase D signaling pathway     103078639 (PLCB4)    04071 Sphingolipid signaling pathway     103078639 (PLCB4)    04022 cGMP-PKG signaling pathway     103078639 (PLCB4)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04540 Gap junction     103078639 (PLCB4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103078639 (PLCB4)    04613 Neutrophil extracellular trap formation     103078639 (PLCB4)    04621 NOD-like receptor signaling pathway     103078639 (PLCB4)    04062 Chemokine signaling pathway     103078639 (PLCB4)   09152 Endocrine system    04911 Insulin secretion     103078639 (PLCB4)    04922 Glucagon signaling pathway     103078639 (PLCB4)    04929 GnRH secretion     103078639 (PLCB4)    04912 GnRH signaling pathway     103078639 (PLCB4)    04915 Estrogen signaling pathway     103078639 (PLCB4)    04921 Oxytocin signaling pathway     103078639 (PLCB4)    04926 Relaxin signaling pathway     103078639 (PLCB4)    04935 Growth hormone synthesis, secretion and action     103078639 (PLCB4)    04918 Thyroid hormone synthesis     103078639 (PLCB4)    04919 Thyroid hormone signaling pathway     103078639 (PLCB4)    04928 Parathyroid hormone synthesis, secretion and action     103078639 (PLCB4)    04916 Melanogenesis     103078639 (PLCB4)    04924 Renin secretion     103078639 (PLCB4)    04925 Aldosterone synthesis and secretion     103078639 (PLCB4)    04927 Cortisol synthesis and secretion     103078639 (PLCB4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     103078639 (PLCB4)    04270 Vascular smooth muscle contraction     103078639 (PLCB4)   09154 Digestive system    04970 Salivary secretion     103078639 (PLCB4)    04971 Gastric acid secretion     103078639 (PLCB4)    04972 Pancreatic secretion     103078639 (PLCB4)    04973 Carbohydrate digestion and absorption     103078639 (PLCB4)   09155 Excretory system    04961 Endocrine and other factor-regulated calcium reabsorption     103078639 (PLCB4)   09156 Nervous system    04724 Glutamatergic synapse     103078639 (PLCB4)    04725 Cholinergic synapse     103078639 (PLCB4)    04728 Dopaminergic synapse     103078639 (PLCB4)    04726 Serotonergic synapse     103078639 (PLCB4)    04720 Long-term potentiation     103078639 (PLCB4)    04730 Long-term depression     103078639 (PLCB4)    04723 Retrograde endocannabinoid signaling     103078639 (PLCB4)   09157 Sensory system    04742 Taste transduction     103078639 (PLCB4)    04750 Inflammatory mediator regulation of TRP channels     103078639 (PLCB4)   09159 Environmental adaptation    04713 Circadian entrainment     103078639 (PLCB4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103078639 (PLCB4)   09164 Neurodegenerative disease    05010 Alzheimer disease     103078639 (PLCB4)    05016 Huntington disease     103078639 (PLCB4)    05017 Spinocerebellar ataxia     103078639 (PLCB4)    05022 Pathways of neurodegeneration - multiple diseases     103078639 (PLCB4)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     103078639 (PLCB4)    04934 Cushing syndrome     103078639 (PLCB4)   09172 Infectious disease: viral    05163 Human cytomegalovirus infection     103078639 (PLCB4)   09174 Infectious disease: parasitic    05146 Amoebiasis     103078639 (PLCB4)    05142 Chagas disease     103078639 (PLCB4)    05143 African trypanosomiasis     103078639 (PLCB4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:lve04131]     103078639 (PLCB4) Enzymes [BR:lve01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.4  Phosphoric-diester hydrolases     3.1.4.11  phosphoinositide phospholipase C      103078639 (PLCB4) Membrane trafficking [BR:lve04131]  Exocytosis   Calcium ion-dependent exocytosis    Phospholipases     103078639 (PLCB4)  Endocytosis   Macropinocytosis    Phospholipase C     103078639 (PLCB4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PI-PLC-X PH_14 PI-PLC-Y DUF1154 EF-hand_like C2 EF-hand_7 EF-hand_6 Motif Other DBs NCBI-GeneID:  103078639 NCBI-ProteinID:  XP_007452098 UniProt:  A0A340WRF6 LinkDB All DBs Position Un AA seq 1194 aa AA seqDB search MAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVL ECSLINSVRLGATPKDPKILAALEAIGKSENDLEGRVVCVCSGTDLVNISFTYMVAENSE VTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEK VIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD QLVSFLNEHQRDPRLNEILFPFYDTKRAMQIIEMYEPDEDLKKKGQISSDGFCRYLMSDE NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM SKYCEDLFGDLLLKQALESHPLEPGRPLPSPNDLKRKILIKNKRLKPEVEKKQLEALKSM MEAGESAAPVNILEDDNEEEIESAEQEEEAHPEYKYGNELSADDLGHKEAIANSVKKGLV TIEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVG LGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQL NQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGT YVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRLAVYDDNNK LIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKK FLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKASVTPQSSSELRPTTTAA LGAGLEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQ VDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQH TKEWSDMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQ AKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQ LEHLEFLEKQNEQLLKSCHAVSQTQGEGDAADGEIGSRDGPQTSNSCVKLQDTN NT seq 3585 nt NT seq  +upstreamnt  +downstreamnt atggccaaaccttatgaatttaattggcagaaggaagttccttcgtttttgcaagaagga gcagtttttgacagatatgaagaggaatcctttgtgtttgaacccaactgcctcttcaag gtggatgaatttggcttctttctgacctggagaagtgaaggcaaggaaggacaagttcta gaatgttctctcatcaacagtgttcgactgggagccacaccaaaggatcccaaaattttg gctgctcttgaagctattggaaagtcagaaaatgacctggaagggcgggtagtttgtgtc tgcagtggtacagatctggtgaacatcagtttcacatacatggtggctgaaaattcagaa gtaactaagcaatgggtcgaaggcctgagatccatcatacacaacttcagggccaacaat gtcagtcccatgacatgcctcaagaaacactggatgaaattggcatttatgaccaacaca aatgggaaaattccagttaggagtattaccagaacctttgcatcggggaaaacagaaaag gtgatctttcaagcactcaaggagctaggtcttcccagtggaaagaatgatgaaattgaa cctgcagcatttacttatgaaaagttctatgaactgacacaaaagatttgtcctcggaca gatatagaggatctttttaaaaaaatcaatggagacaaaactgattatttaacggtagac caattagtgagctttctaaatgaacatcaacgagatcctcgattgaatgaaattttattc ccattttatgatactaaaagggcaatgcagatcattgagatgtatgagcctgatgaagac ttgaagaaaaaaggccaaatatcaagtgatgggttttgcagatacctgatgtcagatgaa aatgccccagtcttcctagatcgcctagagctttaccaagaaatggaccaccctctggct cactacttcatcagctcttcccacaacacctatctcactggcagacagtttggtggcaag tcttcagtagaaatgtacagacaggtcctcctggctggttgcagatgtgttgaacttgac tgttgggatggaaaaggtgaggaccaagaaccaataataactcatggaaaagcaatgtgc acagatatcctttttaaggatgttattcaagccatcaaggaaactgcatttgtcacatct gaatatcctgtaattctctcctttgaaaatcactgcagcaaatatcaacagtacaagatg tccaaatattgcgaagatctatttggagatctcctgttgaaacaagcacttgaatcacat ccactggaaccaggcaggcctttgccatccccaaatgacctcaaaagaaaaatactcatc aaaaataaacggctgaaacctgaggttgaaaaaaaacagcttgaagctttgaaaagtatg atggaagcaggagaatccgctgccccagtgaacatcttagaggatgacaatgaagaggaa atagaaagtgctgagcaagaggaagaagctcaccctgaatacaaatatggaaatgaactt tctgcggacgacttgggtcacaaggaagctattgccaatagtgttaagaagggcctggta actatagaagatgagcaggcatggatggcatcttataaatatgtaggcgccaccactaat atccatccatatttgtccacaatgatcaactatgcacagcccgtaaagtttcaaggtttc cacgtggctgaagaacgcaatattcattataacatgtcttcttttaatgagtcagttggt ctaggctacttgaagacacatgcgattgaatttgtgaattataacaaacggcaaatgagc cgcatttaccccaagggaggccgagtcgattccagtaattacatgcctcagattttctgg aacgctggctgccagatggtttcgctgaactatcaaaccccagatttagcgatgcaattg aatcagggaaaatttgagtataatggatcgtgcgggtaccttctcaaaccagatttcatg agacggcccgatagaacatttgatcccttctctgaaacgcctgttgatggggttattgca gccacttgctcagtgcaggtcatatcaggtcagttcttatcagataaaaaaattggcaca tatgtagaagtggatatgtatgggttgcccaccgacactatccggaaggaattccgaaca cgcatggtgatgaacaatggactcaatccagtttacaatgaagaatcatttgtatttcgg aaggtgatcctccctgacctggcagtcttgagacttgcagtgtatgatgacaacaacaag ctgattggccagaggattctgccactggatggcctccaagcaggctatcgacacatttct cttcgaaatgagggaaataaacctttatcactgccaacaattttctgcaatattgttctt aaaacatatgtgcctgatggatttggagatattgtggatgctttatcagatccaaagaaa tttctttccattacggaaaagagagcagaccaaatgagagctatgggcattgaaactagt gacatcgccgacgtgcccagtgacacgtcaaagaatgacaagaaagggaaagccaacaca gcgaaagcaagtgtgacccctcagagcagctcagagctcaggcccaccaccacggctgcc ctgggagctggcctggaggccaagaaaggtattgaactgatccctcaagtgaggatagaa gatttaaagcagatgaaggcttacttgaagcatttaaagaaacaacagaaggagctcaat tctttaaagaagaaacatgcaaaggagcacagtaccatgcagaagctacattgcacacaa gttgacaaaattgtggcacagtatgacaaggagaagtcaactcatgagaaaatcctagag aaggcaatgaagaagaaggggggaagtaattgtcttgaaatgaagaaagaaacagaaatt aaaattcagacgctgacatcagatcacaaatctaaggtcaaggagatcgtggcgcagcac acaaaagagtggtcagacatgatcaacacccacagtgcagaggagcaggagatccgggat ctgcacctcagccagcagtgcgagctgctcaaaaagctcctgatcaacgcccacgagcag cagacccagcagttgaaactgtcccatgacagggaaagcaaggaaatgcgagcacaccag gctaagatttctatggaaaatagcaaagccatcagccaagataaatctatcaagaataaa gcagaacgggaaaggcgggtcagggagttaaacagcagcaacactaaaaagtttctggaa gaaagaaagcgactcgcaatgaagcagtccaaagaaatggaccagttgaaaaaagtccag cttgaacacctcgaattcctagagaaacagaacgagcagcttttgaaatcctgtcatgca gtgtcccaaacgcaaggcgaaggagatgcagcagatggtgaaattggaagccgagatgga ccgcagaccagcaacagttgtgtgaaactccaggacacaaactga

Lipotes vexillifer (Yangtze River dolphin): 103079287 Help Entry 103079287         CDS       T03090                                  Gene name PLCB1 Definition (RefSeq) phospholipase C beta 1   KO K05858   phosphatidylinositol phospholipase C, beta [EC:3.1.4.11] Organism lve  Lipotes vexillifer (Yangtze River dolphin) Pathway lve00562   Inositol phosphate metabolism lve01100   Metabolic pathways lve04015   Rap1 signaling pathway lve04020   Calcium signaling pathway lve04022   cGMP-PKG signaling pathway lve04062   Chemokine signaling pathway lve04070   Phosphatidylinositol signaling system lve04071   Sphingolipid signaling pathway lve04072   Phospholipase D signaling pathway lve04261   Adrenergic signaling in cardiomyocytes lve04270   Vascular smooth muscle contraction lve04310   Wnt signaling pathway lve04371   Apelin signaling pathway lve04540   Gap junction lve04611   Platelet activation lve04613   Neutrophil extracellular trap formation lve04621   NOD-like receptor signaling pathway lve04713   Circadian entrainment lve04720   Long-term potentiation lve04723   Retrograde endocannabinoid signaling lve04724   Glutamatergic synapse lve04725   Cholinergic synapse lve04726   Serotonergic synapse lve04728   Dopaminergic synapse lve04730   Long-term depression lve04742   Taste transduction lve04750   Inflammatory mediator regulation of TRP channels lve04911   Insulin secretion lve04912   GnRH signaling pathway lve04915   Estrogen signaling pathway lve04916   Melanogenesis lve04918   Thyroid hormone synthesis lve04919   Thyroid hormone signaling pathway lve04921   Oxytocin signaling pathway lve04922   Glucagon signaling pathway lve04924   Renin secretion lve04925   Aldosterone synthesis and secretion lve04926   Relaxin signaling pathway lve04927   Cortisol synthesis and secretion lve04928   Parathyroid hormone synthesis, secretion and action lve04929   GnRH secretion lve04933   AGE-RAGE signaling pathway in diabetic complications lve04934   Cushing syndrome lve04935   Growth hormone synthesis, secretion and action lve04961   Endocrine and other factor-regulated calcium reabsorption lve04970   Salivary secretion lve04971   Gastric acid secretion lve04972   Pancreatic secretion lve04973   Carbohydrate digestion and absorption lve05010   Alzheimer disease lve05016   Huntington disease lve05017   Spinocerebellar ataxia lve05022   Pathways of neurodegeneration - multiple diseases lve05142   Chagas disease lve05143   African trypanosomiasis lve05146   Amoebiasis lve05163   Human cytomegalovirus infection lve05200   Pathways in cancer Module lve_M00130   Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Brite KEGG Orthology (KO) [BR:lve00001]  09100 Metabolism   09101 Carbohydrate metabolism    00562 Inositol phosphate metabolism     103079287 (PLCB1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103079287 (PLCB1)    04310 Wnt signaling pathway     103079287 (PLCB1)    04371 Apelin signaling pathway     103079287 (PLCB1)    04020 Calcium signaling pathway     103079287 (PLCB1)    04070 Phosphatidylinositol signaling system     103079287 (PLCB1)    04072 Phospholipase D signaling pathway     103079287 (PLCB1)    04071 Sphingolipid signaling pathway     103079287 (PLCB1)    04022 cGMP-PKG signaling pathway     103079287 (PLCB1)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04540 Gap junction     103079287 (PLCB1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103079287 (PLCB1)    04613 Neutrophil extracellular trap formation     103079287 (PLCB1)    04621 NOD-like receptor signaling pathway     103079287 (PLCB1)    04062 Chemokine signaling pathway     103079287 (PLCB1)   09152 Endocrine system    04911 Insulin secretion     103079287 (PLCB1)    04922 Glucagon signaling pathway     103079287 (PLCB1)    04929 GnRH secretion     103079287 (PLCB1)    04912 GnRH signaling pathway     103079287 (PLCB1)    04915 Estrogen signaling pathway     103079287 (PLCB1)    04921 Oxytocin signaling pathway     103079287 (PLCB1)    04926 Relaxin signaling pathway     103079287 (PLCB1)    04935 Growth hormone synthesis, secretion and action     103079287 (PLCB1)    04918 Thyroid hormone synthesis     103079287 (PLCB1)    04919 Thyroid hormone signaling pathway     103079287 (PLCB1)    04928 Parathyroid hormone synthesis, secretion and action     103079287 (PLCB1)    04916 Melanogenesis     103079287 (PLCB1)    04924 Renin secretion     103079287 (PLCB1)    04925 Aldosterone synthesis and secretion     103079287 (PLCB1)    04927 Cortisol synthesis and secretion     103079287 (PLCB1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     103079287 (PLCB1)    04270 Vascular smooth muscle contraction     103079287 (PLCB1)   09154 Digestive system    04970 Salivary secretion     103079287 (PLCB1)    04971 Gastric acid secretion     103079287 (PLCB1)    04972 Pancreatic secretion     103079287 (PLCB1)    04973 Carbohydrate digestion and absorption     103079287 (PLCB1)   09155 Excretory system    04961 Endocrine and other factor-regulated calcium reabsorption     103079287 (PLCB1)   09156 Nervous system    04724 Glutamatergic synapse     103079287 (PLCB1)    04725 Cholinergic synapse     103079287 (PLCB1)    04728 Dopaminergic synapse     103079287 (PLCB1)    04726 Serotonergic synapse     103079287 (PLCB1)    04720 Long-term potentiation     103079287 (PLCB1)    04730 Long-term depression     103079287 (PLCB1)    04723 Retrograde endocannabinoid signaling     103079287 (PLCB1)   09157 Sensory system    04742 Taste transduction     103079287 (PLCB1)    04750 Inflammatory mediator regulation of TRP channels     103079287 (PLCB1)   09159 Environmental adaptation    04713 Circadian entrainment     103079287 (PLCB1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103079287 (PLCB1)   09164 Neurodegenerative disease    05010 Alzheimer disease     103079287 (PLCB1)    05016 Huntington disease     103079287 (PLCB1)    05017 Spinocerebellar ataxia     103079287 (PLCB1)    05022 Pathways of neurodegeneration - multiple diseases     103079287 (PLCB1)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     103079287 (PLCB1)    04934 Cushing syndrome     103079287 (PLCB1)   09172 Infectious disease: viral    05163 Human cytomegalovirus infection     103079287 (PLCB1)   09174 Infectious disease: parasitic    05146 Amoebiasis     103079287 (PLCB1)    05142 Chagas disease     103079287 (PLCB1)    05143 African trypanosomiasis     103079287 (PLCB1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:lve04131]     103079287 (PLCB1) Enzymes [BR:lve01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.4  Phosphoric-diester hydrolases     3.1.4.11  phosphoinositide phospholipase C      103079287 (PLCB1) Membrane trafficking [BR:lve04131]  Exocytosis   Calcium ion-dependent exocytosis    Phospholipases     103079287 (PLCB1)  Endocytosis   Macropinocytosis    Phospholipase C     103079287 (PLCB1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PI-PLC-X PLC-beta_C PH_14 PI-PLC-Y EF-hand_like DUF1154 Motif Other DBs NCBI-GeneID:  103079287 NCBI-ProteinID:  XP_007452101 UniProt:  A0A340WT67 LinkDB All DBs Position Un AA seq 1216 aa AA seqDB search MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQSKE TELLDLSLVKDARCGKHAKAPKDPKLRELLDVGNIGRLEHRMITVVYGPDLVNISHLNLV AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA DRKRVETALEACSLPSSRNDLIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLS GEENGVVPPEKLDLNEDMSQPLTHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPLDLMYKILVKNKKKSHKSSEGSGKK KLSEQTSNTYSDSSSVFEPSSPGAGEADTESDDDDDEDDCKKSSMDEGTAGSEAMATEEM SNLVNYIQPVKFESFEISKKRNRSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK GTRVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG NAVNPVWEEEPIVFKKVVLPSLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNER NQPLMLPALFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK EADPGETQSEAPSEARTTPAENGMNHTTSLTPKPPSQALHSQPAPGSVKAPAKTEDLIQS VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL RRRAALEKTAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKP KLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHSSAPPLLTSDPGKLNHKPPSS EKLEGENPGKEFDTPL NT seq 3651 nt NT seq  +upstreamnt  +downstreamnt atggccggggctcagcccggagtacacgctctgcaactcaagcccgtgtgcgtgtccgac agcctcaagaagggcaccaaattcgtcaagtgggatgatgactccactattgtcactcca attattttgaggaccgaccctcagggatttttcttttactggacagatcaaagcaaggag acggagctgttagatctcagccttgtcaaagatgccagatgtgggaaacacgccaaggct cccaaggaccccaaattacgtgaacttctggatgtggggaacatcgggcgcctggaacat cgcatgataacagtggtgtatgggcctgacttagttaacatctcccatttgaacctcgtg gctttccaagaagaagtggccaaggaatggacaaatgaagttttcagtctggcaacgaac ctgctggcccaaaacatgtctagggatgcatttctggaaaaagcctatactaaacttaag ctgcaagtcactccagaaggacgcattcctctcaaaaacatataccgcttgttctcagca gaccggaagcgagttgaaactgctttagaggcttgtagtcttccatcttcgaggaatgat ttgatacctcaagaagatttcaccccagaagtgtacagagttttcctgaacaacctttgt cctcgacctgaaattgataacatcttttccgaatttggtgccaaaagtaaaccatacctt acggttgatcagatgatggattttatcaacctcaagcagcgagatcccaggctaaatgaa attctgtacccacctttaaagcaagagcaagtccaagtgttgattgagaagtatgaaccc aacaacagtcttgccagaaaaggacagatatcagtggatggatttatgcgctatctgagt ggagaagaaaatggagtcgttccacctgagaaactggatttgaatgaagatatgtctcag ccacttactcactatttcattaattcctcacacaacacctacctcacagctggccagctg gctggaaactcctccgtcgagatgtatcgccaagtgctcctgtctggttgtcgctgtgtg gagttggactgctggaagggacggaccgcagaagaggagccagtcatcacccatgggttc accatgaccacggagatatccttcaaggaagtgatagaagccattgctgagtgtgcattt aagacttcaccttttccaattctgctttcatttgagaaccacgtggattccccaaagcag caggccaagatggcagagtattgccggctgatcttcggggacgcccttctcatggagccc ctggaaaagtacccactggaatctggagttcctcttccaagccctctggacttaatgtac aaaatcttggtgaaaaataagaagaaatcccacaaatcgtcagaaggaagtggcaaaaag aagctctcagaacaaacctccaacacgtacagcgactcctccagtgtgtttgagccctcg tccccaggagctggagaagctgatacggagagtgacgatgatgacgatgaggatgactgt aaaaagtcttcgatggatgaggggactgctgggagcgaggccatggccacagaagagatg tctaatctggtgaactatattcagccagtcaagttcgagtcattcgaaatttcaaaaaaa agaaacagaagcttcgaaatgtcctcctttgtggaaaccaaaggacttgagcaacttaca aagtccccagtggaatttgtagaatataacaaaatgcagcttagcaggatatatccaaaa ggaacacgtgtggattcatccaactacatgccccagctcttctggaatgcaggctgccaa atggttgcacttaatttccaaacagtggacctggctatgcaaataaacatggggatgtat gaatacaatgggaaaagtggctacagactgaagccagagttcatgaggagacctgacaag cactttgatccattcaccgaaggcattgtggatgggatcgtggccaacactttatctgtt aagattatttcaggtcagtttctctctgataagaaagtcgggacttatgtggaagtggat atgtttggtttgcctgtggacacaaggaggaaggcatttaagacaaagacatcacaagga aatgctgtaaatcctgtctgggaagaagaacccattgtgttcaaaaaggtagttcttcct tctctggcctgtttgaggatagcagtttatgaagaaggaggtaaatttattggtcaccga atcttgccagtacaagcgattcgaccaggctatcactacatctgtctgaggaatgaaagg aaccagcctctgatgctgccagctctcttcgtctacatagaggtgaaggactatgtccca gatacatatgcagatgtgattgaagctttgtcaaatccaatccgatatgtgaatctgatg gagcagagagctaaacaactggcagctttgactctggaagatgaagaagaagtaaagaaa gaggctgatcctggggaaacacagtcagaagctccaagtgaagccaggacaactccagca gaaaacgggatgaatcacactacatccctgacacccaaaccaccctcccaggctctccac agccaaccagctccaggctctgtaaaggcacctgccaaaacagaagatcttattcagagt gttttaacagaagtagaggcgcagacaattgaagagctaaagcaacagaagtcgtttgtg aaacttcaaaagaagcactacaaagaaatgaaagacctggttaagagacaccacaagaaa accaccgaccttatcaaagaacacactacaaaatataatgaaatccagaatgactacttg cgaaggagggcagctttggaaaagacagccaaaaaggatagtaagaaaaaatcggaaccc agcagccctgaccatggttcatcaacaattgagcaagaccttgctgccctggatgccgaa atgacccaaaagttaatagatttgaaggacaaacaacagcagcagctgcttaatcttcga caagaacagtattacagtgaaaaataccagaagcgagaacatattaaactgcttattcaa aaattgacagatgttgctgaagaatgtcagaataatcagttaaagaagcttaaagaaatt tgtgagaaagagaagaaggaattaaagaagaaaatggataaaaagaggcaggagaagata acagaagctaaatccaaagacaaaagccagatggaagaggaaaagacagagatgatccgg tcatacatccaggaggtggtgcagtacatcaagaggttagaagaggcacaaagtaaacgg caagaaaaactcgtagagaaacacaaagagatacgtcagcagatcctggacgaaaagccc aagctgcaggtggagctagagcaggagtaccaagacaagttcaaaaggctgcctctggag attttggaattcgtgcaagaagccatgaaagggaagatcagtgaagacagcaatcacagc tctgcccctcccctgctgacctcagaccctggaaaactgaaccacaagcctccttccagt gagaagctggaaggagaaaacccaggaaaagaatttgatactcccctgtga

Lipotes vexillifer (Yangtze River dolphin): 103083884 Help Entry 103083884         CDS       T03090                                  Gene name PLCB3 Definition (RefSeq) phospholipase C beta 3   KO K05858   phosphatidylinositol phospholipase C, beta [EC:3.1.4.11] Organism lve  Lipotes vexillifer (Yangtze River dolphin) Pathway lve00562   Inositol phosphate metabolism lve01100   Metabolic pathways lve04015   Rap1 signaling pathway lve04020   Calcium signaling pathway lve04022   cGMP-PKG signaling pathway lve04062   Chemokine signaling pathway lve04070   Phosphatidylinositol signaling system lve04071   Sphingolipid signaling pathway lve04072   Phospholipase D signaling pathway lve04261   Adrenergic signaling in cardiomyocytes lve04270   Vascular smooth muscle contraction lve04310   Wnt signaling pathway lve04371   Apelin signaling pathway lve04540   Gap junction lve04611   Platelet activation lve04613   Neutrophil extracellular trap formation lve04621   NOD-like receptor signaling pathway lve04713   Circadian entrainment lve04720   Long-term potentiation lve04723   Retrograde endocannabinoid signaling lve04724   Glutamatergic synapse lve04725   Cholinergic synapse lve04726   Serotonergic synapse lve04728   Dopaminergic synapse lve04730   Long-term depression lve04742   Taste transduction lve04750   Inflammatory mediator regulation of TRP channels lve04911   Insulin secretion lve04912   GnRH signaling pathway lve04915   Estrogen signaling pathway lve04916   Melanogenesis lve04918   Thyroid hormone synthesis lve04919   Thyroid hormone signaling pathway lve04921   Oxytocin signaling pathway lve04922   Glucagon signaling pathway lve04924   Renin secretion lve04925   Aldosterone synthesis and secretion lve04926   Relaxin signaling pathway lve04927   Cortisol synthesis and secretion lve04928   Parathyroid hormone synthesis, secretion and action lve04929   GnRH secretion lve04933   AGE-RAGE signaling pathway in diabetic complications lve04934   Cushing syndrome lve04935   Growth hormone synthesis, secretion and action lve04961   Endocrine and other factor-regulated calcium reabsorption lve04970   Salivary secretion lve04971   Gastric acid secretion lve04972   Pancreatic secretion lve04973   Carbohydrate digestion and absorption lve05010   Alzheimer disease lve05016   Huntington disease lve05017   Spinocerebellar ataxia lve05022   Pathways of neurodegeneration - multiple diseases lve05142   Chagas disease lve05143   African trypanosomiasis lve05146   Amoebiasis lve05163   Human cytomegalovirus infection lve05200   Pathways in cancer Module lve_M00130   Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Brite KEGG Orthology (KO) [BR:lve00001]  09100 Metabolism   09101 Carbohydrate metabolism    00562 Inositol phosphate metabolism     103083884 (PLCB3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103083884 (PLCB3)    04310 Wnt signaling pathway     103083884 (PLCB3)    04371 Apelin signaling pathway     103083884 (PLCB3)    04020 Calcium signaling pathway     103083884 (PLCB3)    04070 Phosphatidylinositol signaling system     103083884 (PLCB3)    04072 Phospholipase D signaling pathway     103083884 (PLCB3)    04071 Sphingolipid signaling pathway     103083884 (PLCB3)    04022 cGMP-PKG signaling pathway     103083884 (PLCB3)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04540 Gap junction     103083884 (PLCB3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103083884 (PLCB3)    04613 Neutrophil extracellular trap formation     103083884 (PLCB3)    04621 NOD-like receptor signaling pathway     103083884 (PLCB3)    04062 Chemokine signaling pathway     103083884 (PLCB3)   09152 Endocrine system    04911 Insulin secretion     103083884 (PLCB3)    04922 Glucagon signaling pathway     103083884 (PLCB3)    04929 GnRH secretion     103083884 (PLCB3)    04912 GnRH signaling pathway     103083884 (PLCB3)    04915 Estrogen signaling pathway     103083884 (PLCB3)    04921 Oxytocin signaling pathway     103083884 (PLCB3)    04926 Relaxin signaling pathway     103083884 (PLCB3)    04935 Growth hormone synthesis, secretion and action     103083884 (PLCB3)    04918 Thyroid hormone synthesis     103083884 (PLCB3)    04919 Thyroid hormone signaling pathway     103083884 (PLCB3)    04928 Parathyroid hormone synthesis, secretion and action     103083884 (PLCB3)    04916 Melanogenesis     103083884 (PLCB3)    04924 Renin secretion     103083884 (PLCB3)    04925 Aldosterone synthesis and secretion     103083884 (PLCB3)    04927 Cortisol synthesis and secretion     103083884 (PLCB3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     103083884 (PLCB3)    04270 Vascular smooth muscle contraction     103083884 (PLCB3)   09154 Digestive system    04970 Salivary secretion     103083884 (PLCB3)    04971 Gastric acid secretion     103083884 (PLCB3)    04972 Pancreatic secretion     103083884 (PLCB3)    04973 Carbohydrate digestion and absorption     103083884 (PLCB3)   09155 Excretory system    04961 Endocrine and other factor-regulated calcium reabsorption     103083884 (PLCB3)   09156 Nervous system    04724 Glutamatergic synapse     103083884 (PLCB3)    04725 Cholinergic synapse     103083884 (PLCB3)    04728 Dopaminergic synapse     103083884 (PLCB3)    04726 Serotonergic synapse     103083884 (PLCB3)    04720 Long-term potentiation     103083884 (PLCB3)    04730 Long-term depression     103083884 (PLCB3)    04723 Retrograde endocannabinoid signaling     103083884 (PLCB3)   09157 Sensory system    04742 Taste transduction     103083884 (PLCB3)    04750 Inflammatory mediator regulation of TRP channels     103083884 (PLCB3)   09159 Environmental adaptation    04713 Circadian entrainment     103083884 (PLCB3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103083884 (PLCB3)   09164 Neurodegenerative disease    05010 Alzheimer disease     103083884 (PLCB3)    05016 Huntington disease     103083884 (PLCB3)    05017 Spinocerebellar ataxia     103083884 (PLCB3)    05022 Pathways of neurodegeneration - multiple diseases     103083884 (PLCB3)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     103083884 (PLCB3)    04934 Cushing syndrome     103083884 (PLCB3)   09172 Infectious disease: viral    05163 Human cytomegalovirus infection     103083884 (PLCB3)   09174 Infectious disease: parasitic    05146 Amoebiasis     103083884 (PLCB3)    05142 Chagas disease     103083884 (PLCB3)    05143 African trypanosomiasis     103083884 (PLCB3)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:lve04131]     103083884 (PLCB3) Enzymes [BR:lve01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.4  Phosphoric-diester hydrolases     3.1.4.11  phosphoinositide phospholipase C      103083884 (PLCB3) Membrane trafficking [BR:lve04131]  Exocytosis   Calcium ion-dependent exocytosis    Phospholipases     103083884 (PLCB3)  Endocytosis   Macropinocytosis    Phospholipase C     103083884 (PLCB3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PI-PLC-X PLC-beta_C PH_14 PI-PLC-Y EF-hand_like C2 DUF1154 Motif Other DBs NCBI-GeneID:  103083884 NCBI-ProteinID:  XP_007462136 UniProt:  A0A340XL55 LinkDB All DBs Position Un AA seq 1230 aa AA seqDB search MAGARPGVHALQLEPPTVVETLRRGSKFIKWDEEASSRNLVTLRVDPSGFFLYWTGPNME VDILDISSIRDTRTGRYARLPKDPKIREVLGFGGPDARLEEKLMTVVAGPDPVNTSFLNF MAVQDDTAKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFS ADKKRVETALESCGLNFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGKPY LTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKYEPNQQFLERDQMSMEGFSRYL GGEENGILPLEALDLSADMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRC VELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAK QQAKMAEYCRSIFGDALLIDPLDKYPLAPGVPLPSPQDLMGRILVKNKKRHRPSTGVPDS SVRKRPLEQSNSALSESSAATEPSSPQLGSPSSDSCPGLSNGEEAGLEKPSLEPQKSLGE ESLQRGPDALGSAYREDEEEDEEEEEQTDPKKPTTDEGTASSEVNATEEMSTLVNYIEPV KFKSFEAARKRNRCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNYM PQLFWNVGCQLVALNFQTLDVAMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIV DGIVANAVRVKVISGQFLSDRKVGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDEEP FDFPKVVLPTLALLRIAAFEEGGKFVGHRILPVSAIRSGYHYICLRNEANQPLCLPALLI YTEASDYIPDDHQDYAEALINPIKHVSLMDQRAKQLAALIGESEAQAGPETSQETQSQQP GSQLTPNPTPSPLDTSPRRPPGPVTSSTSTSLSSPGQRDDLIASVLSEVAPAPLDELRGH KALVKLQSRQERDFRELHKKHQRKAVALTRRLLDNLAQAQAESRCRHRPGVLGGEDEREE EEEVKRYQEFQKKQVQRLLELREAQADTEAERRLEHLRQAQQRLREIVMDAHITQFKRLK EMNEREKKELQKILDRKRHNSISEAKTREKHKKEAELTEINRRHITESVNSIRRLEEAQK QRQERLVAAQQQILQQLTEEEPKLLAQLAQECQEQRERLPREIRRSLLGETPEGLGDGHL VACASNGHAPGSSGHLSGADSESQEETTKL NT seq 3693 nt NT seq  +upstreamnt  +downstreamnt atggcgggcgccaggcccggcgtccacgcgctgcagctggagccgcccaccgtcgtggag accctgcggcgtgggagtaagttcatcaaatgggacgaggaggcctccagtcggaacctg gtaactctgcgcgtggaccctagtggcttcttcctgtactggacagggcccaacatggag gtggacatactggacatcagttccatcagggacacgaggacaggccgttatgcccgccta cccaaggaccccaagattcgggaggtgttgggctttgggggccctgatgcccggttggag gaaaagttgatgacagtggtggccgggccagacccggtgaatacatcgtttttgaacttc atggccgtgcaggatgacacagccaaggtctggtccgaggagctgttcaagctggctatg aacatcctggctcagaatgcctcccggaacaccttcttgcgcaaagcgtacacgaagctg aaactgcaggtgaaccaggatggacggatcccggtcaagaacatcctgaagatgttctca gcagacaagaagcgggtagaaactgcactggaatcctgtggcctcaatttcaaccggagc gagtccatccggcctgacgagttttccttggaaatcttcgagcggttcttgaacaagctt tgtctgcggccggacattgacaagatcctgctggagataggcgccaagggcaaaccatac ctgacactggagcagctcatggacttcatcaaccagaagcaacgggacccgaggctcaat gaggtgctgtacccgcctctgcggccctcccaggcccggctgcttatcgagaagtatgag cccaaccagcagttcctggagagagaccagatgtccatggagggcttcagccgctacctg ggaggtgaggagaacggcatcctgcccctagaggctctggatctgagcgcagacatgacc cagccgctcagcgcctatttcatcaactcctcacacaacacctatctcactgcggggcag ctggcgggaacctcgtcggtggagatgtaccggcaggcactgctgtggggctgccgctgc gtggagctggacgtgtggaaagggcggccgcctgaggaggagcccttcatcacccacggc ttcaccatgaccacggaggtgccgctgcgagatgtgctggaggccattgcggagactgcc ttcaagacctcaccctaccctgtcatcctctcctttgagaaccatgtggactcggcaaag cagcaggccaagatggctgagtactgccgctccatctttggggacgcgctgctcatcgac cccctggacaagtacccgctggccccgggcgtccccctgcccagcccccaggacctgatg ggccgcatcctggtgaagaacaagaagcggcaccggcccagcactggcgttcctgacagc tccgtgcgcaagcggccgctagagcagagcaactcggccctgagcgagagctccgccgcc accgagccctcctcaccccagctcgggtcccccagctctgacagctgcccaggcctgagc aatggggaggaggcgggccttgagaagcccagcctggagcctcagaagtctctgggtgag gagagtttgcagcggggccctgatgcccttggatctgcctaccgtgaggatgaggaagag gatgaggaagaggaggaacagacggatcccaaaaagccgaccaccgacgagggcactgcc agcagtgaggtcaatgccactgaggaaatgtcgacacttgtcaactacatcgagcccgtc aagttcaagtcctttgaggctgctcgaaagaggaacaggtgcttcgagatgtcgtccttt gtggagaccaaggccatggagcaactgaccaagagccccatggagtttgtggaatacaac aagcagcagctcagccgcatctaccccaagggcacacgcgtggactcgtccaactacatg ccccagctcttctggaacgtgggctgccagctcgtcgcgctcaacttccagaccctggac gtggccatgcagctcaacgcgggcgtgttcgagtacaacgggcgcagtggctacctactc aagcccgagttcatgcggcggccggacaagtcctttgaccccttcactgaggtcatcgtg gacggcatcgtggccaatgccgtgcgggtcaaggtgatctcggggcagttcctgtccgac aggaaggtgggcatctacgtggaggtggatatgttcggcctccctgtcgacacgcggcgc aagtaccgcactcggacctctcaggggaactcgttcaaccccgtgtgggatgaggagccc ttcgatttccccaaggtggtgctgcccacgctggctttgctgcgcatcgcggcttttgag gagggtggcaagttcgtggggcaccggatcctgcctgtctctgccatccgctcagggtac cactacatctgcctgcggaacgaggccaaccagccactgtgcctgccggccctgctcatc tacactgaggcctctgactatattcctgatgaccaccaagactacgcagaggccctgatc aatcccatcaagcacgtcagcctgatggaccagagggccaagcagctggctgccctcatt ggggagagtgaggctcaggctgggccggagacaagccaggagacccagtctcagcagcca gggtcccagctgaccccaaaccccacacccagcccactggacacctccccccgccggccc ccaggccccgtcacctcctccaccagcacctccctcagcagcccaggtcagcgtgatgac ctcattgccagcgtcctctcagaggtggccccggccccgctggatgagctccgaggccac aaggccctggtgaagctccagagccggcaagagcgagactttcgagagctgcacaagaag catcagcggaaggcggttgccctcacacgccggttgctcgacaacctggcccaggcccag gccgagagcaggtgccggcaccggccgggtgtcctaggcggggaggacgagagggaggag gaggaagaggtgaagaggtatcaagagttccaaaagaagcaggtgcagcgtctgctggag ctgagggaggcccaggcggacacagaggccgagcggaggctggagcacctgagacaggct cagcagaggctcagggagattgtcatggatgctcacatcactcagttcaagagactgaag gagatgaacgagagggagaagaaggaactgcagaagatcctggacaggaagcgccacaac agtatctcagaggcaaagaccagggagaaacataagaaggaggcggaactgacagagatt aaccgtcgacacatcactgagtcggtcaactccatccgtcggctggaggaggcccagaag cagcggcaggaacgccttgtggccgcgcagcagcagattctccaacagctgacagaagag gagcccaagctgctggcccagctggcccaggagtgtcaggagcagcgggagaggctgccc cgggagatccgccggagcctgctgggcgagacgccggagggactgggggacgggcatctg gtggcctgtgccagcaatggtcacgcgcctgggagcagtgggcacctgtccggcgctgat tcggagagtcaagaggagactacgaagctctga

Lipotes vexillifer (Yangtze River dolphin): 103086280 Help Entry 103086280         CDS       T03090                                  Gene name PLCB2 Definition (RefSeq) phospholipase C beta 2   KO K05858   phosphatidylinositol phospholipase C, beta [EC:3.1.4.11] Organism lve  Lipotes vexillifer (Yangtze River dolphin) Pathway lve00562   Inositol phosphate metabolism lve01100   Metabolic pathways lve04015   Rap1 signaling pathway lve04020   Calcium signaling pathway lve04022   cGMP-PKG signaling pathway lve04062   Chemokine signaling pathway lve04070   Phosphatidylinositol signaling system lve04071   Sphingolipid signaling pathway lve04072   Phospholipase D signaling pathway lve04261   Adrenergic signaling in cardiomyocytes lve04270   Vascular smooth muscle contraction lve04310   Wnt signaling pathway lve04371   Apelin signaling pathway lve04540   Gap junction lve04611   Platelet activation lve04613   Neutrophil extracellular trap formation lve04621   NOD-like receptor signaling pathway lve04713   Circadian entrainment lve04720   Long-term potentiation lve04723   Retrograde endocannabinoid signaling lve04724   Glutamatergic synapse lve04725   Cholinergic synapse lve04726   Serotonergic synapse lve04728   Dopaminergic synapse lve04730   Long-term depression lve04742   Taste transduction lve04750   Inflammatory mediator regulation of TRP channels lve04911   Insulin secretion lve04912   GnRH signaling pathway lve04915   Estrogen signaling pathway lve04916   Melanogenesis lve04918   Thyroid hormone synthesis lve04919   Thyroid hormone signaling pathway lve04921   Oxytocin signaling pathway lve04922   Glucagon signaling pathway lve04924   Renin secretion lve04925   Aldosterone synthesis and secretion lve04926   Relaxin signaling pathway lve04927   Cortisol synthesis and secretion lve04928   Parathyroid hormone synthesis, secretion and action lve04929   GnRH secretion lve04933   AGE-RAGE signaling pathway in diabetic complications lve04934   Cushing syndrome lve04935   Growth hormone synthesis, secretion and action lve04961   Endocrine and other factor-regulated calcium reabsorption lve04970   Salivary secretion lve04971   Gastric acid secretion lve04972   Pancreatic secretion lve04973   Carbohydrate digestion and absorption lve05010   Alzheimer disease lve05016   Huntington disease lve05017   Spinocerebellar ataxia lve05022   Pathways of neurodegeneration - multiple diseases lve05142   Chagas disease lve05143   African trypanosomiasis lve05146   Amoebiasis lve05163   Human cytomegalovirus infection lve05200   Pathways in cancer Module lve_M00130   Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Brite KEGG Orthology (KO) [BR:lve00001]  09100 Metabolism   09101 Carbohydrate metabolism    00562 Inositol phosphate metabolism     103086280 (PLCB2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103086280 (PLCB2)    04310 Wnt signaling pathway     103086280 (PLCB2)    04371 Apelin signaling pathway     103086280 (PLCB2)    04020 Calcium signaling pathway     103086280 (PLCB2)    04070 Phosphatidylinositol signaling system     103086280 (PLCB2)    04072 Phospholipase D signaling pathway     103086280 (PLCB2)    04071 Sphingolipid signaling pathway     103086280 (PLCB2)    04022 cGMP-PKG signaling pathway     103086280 (PLCB2)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04540 Gap junction     103086280 (PLCB2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103086280 (PLCB2)    04613 Neutrophil extracellular trap formation     103086280 (PLCB2)    04621 NOD-like receptor signaling pathway     103086280 (PLCB2)    04062 Chemokine signaling pathway     103086280 (PLCB2)   09152 Endocrine system    04911 Insulin secretion     103086280 (PLCB2)    04922 Glucagon signaling pathway     103086280 (PLCB2)    04929 GnRH secretion     103086280 (PLCB2)    04912 GnRH signaling pathway     103086280 (PLCB2)    04915 Estrogen signaling pathway     103086280 (PLCB2)    04921 Oxytocin signaling pathway     103086280 (PLCB2)    04926 Relaxin signaling pathway     103086280 (PLCB2)    04935 Growth hormone synthesis, secretion and action     103086280 (PLCB2)    04918 Thyroid hormone synthesis     103086280 (PLCB2)    04919 Thyroid hormone signaling pathway     103086280 (PLCB2)    04928 Parathyroid hormone synthesis, secretion and action     103086280 (PLCB2)    04916 Melanogenesis     103086280 (PLCB2)    04924 Renin secretion     103086280 (PLCB2)    04925 Aldosterone synthesis and secretion     103086280 (PLCB2)    04927 Cortisol synthesis and secretion     103086280 (PLCB2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     103086280 (PLCB2)    04270 Vascular smooth muscle contraction     103086280 (PLCB2)   09154 Digestive system    04970 Salivary secretion     103086280 (PLCB2)    04971 Gastric acid secretion     103086280 (PLCB2)    04972 Pancreatic secretion     103086280 (PLCB2)    04973 Carbohydrate digestion and absorption     103086280 (PLCB2)   09155 Excretory system    04961 Endocrine and other factor-regulated calcium reabsorption     103086280 (PLCB2)   09156 Nervous system    04724 Glutamatergic synapse     103086280 (PLCB2)    04725 Cholinergic synapse     103086280 (PLCB2)    04728 Dopaminergic synapse     103086280 (PLCB2)    04726 Serotonergic synapse     103086280 (PLCB2)    04720 Long-term potentiation     103086280 (PLCB2)    04730 Long-term depression     103086280 (PLCB2)    04723 Retrograde endocannabinoid signaling     103086280 (PLCB2)   09157 Sensory system    04742 Taste transduction     103086280 (PLCB2)    04750 Inflammatory mediator regulation of TRP channels     103086280 (PLCB2)   09159 Environmental adaptation    04713 Circadian entrainment     103086280 (PLCB2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103086280 (PLCB2)   09164 Neurodegenerative disease    05010 Alzheimer disease     103086280 (PLCB2)    05016 Huntington disease     103086280 (PLCB2)    05017 Spinocerebellar ataxia     103086280 (PLCB2)    05022 Pathways of neurodegeneration - multiple diseases     103086280 (PLCB2)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     103086280 (PLCB2)    04934 Cushing syndrome     103086280 (PLCB2)   09172 Infectious disease: viral    05163 Human cytomegalovirus infection     103086280 (PLCB2)   09174 Infectious disease: parasitic    05146 Amoebiasis     103086280 (PLCB2)    05142 Chagas disease     103086280 (PLCB2)    05143 African trypanosomiasis     103086280 (PLCB2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:lve04131]     103086280 (PLCB2) Enzymes [BR:lve01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.4  Phosphoric-diester hydrolases     3.1.4.11  phosphoinositide phospholipase C      103086280 (PLCB2) Membrane trafficking [BR:lve04131]  Exocytosis   Calcium ion-dependent exocytosis    Phospholipases     103086280 (PLCB2)  Endocytosis   Macropinocytosis    Phospholipase C     103086280 (PLCB2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y C2 EF-hand_like DUF1154 Caskin-Pro-rich AAA_13 Gp58 Motif Other DBs NCBI-GeneID:  103086280 NCBI-ProteinID:  XP_007460267 UniProt:  A0A340XJH6 LinkDB All DBs Position Un AA seq 1420 aa AA seqDB search MSLLNPVLQPPGVKAYLSQGERFIRWDDETIASPVILRVDPKGYYLYWTYQNKEMEFLDI TSIRDTRFGKFAKMPKSQKLRDVFNMDFPDNNFLLKTLTVVSGPDMVDLTFHNFVSYKEN VGKDWAEDVLALAKHPLMANASRSTFLDKSLVKLKMQLNPEGKIPVKNFFQMFPADRKRV EAALSACHLPKGKNDAINPEDFPESVYKSFLMSLCPRPEIDEIFTSYHAKAKPYMTKEHL AKFINQKQRDSRLNSLLFPLARPDQVQGLIDKYEPRGINVQRGQLSPEGMVWFLCGPENS VLAQDKLLLHHDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLAGCRCVELDCW KGKPPDEEPIITHGFTMTTDIYFKEAIEAIAESAFKTSPYPVILSFENHVDSPRQQAKMA EYCRTIFGDMLLTEPLEKFPLKPGIPLPSPEDLRGKILIKNKKKQFSGPPAPSQEPGGEA EGSGPPNVPVGEDTVWAGEEGAELEEEEVEEEEEESGSLDEEGMKEMQSDEGTAGLEVTA YKEMSSLVNYVQPTKFISFESSAQKNRSYVISSFTELKAYDLLSKSSVQFVDYNKRQMSR IYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMALFEFNGQSGYLLKHEFMR RLDKQFNPFSVDRIDVVVATTLSITVISGQFLSERSVRTYVEVELFGLPGDSKRRYRTKL SPSTNSINPVWKEEPFVFEKILMPELASLRVAVMEDGNKFLGHRIIPINALNSGYHHLCL HSESNMPLTMPALFVFLEMKDYVPDTWADLTVALANPIKFFSAHDKKSVKLKEAMGGLPE NPFPLGSPVACQVNAASAPTSNGSAAAGAKAREEATKEAAEPRTASVEELRELKGVVKLQ RRHEKELRELERRGARRWEELLQRGAAQRAELRPPGAGGGGDVRGRKLGPGKGSRKKRTP PGEDPAGAVPAEGPEGAGARLRELRDRLELELLQQGEEQCECVLRCRAQQVAEQMTKMME LAREKQAAELKILKETLETDTKEVKKKLEAKRLDRIQAMMKVTTDKMAQERLKREINNSH IQEVVQVIKQMTENLENHQEKLEEKQAACLEQIREMEKQFQQEALAQYEAKMKGLEVEVK ESVRTYLRACLPSVEEDKPERPCRVSRELCEQDALTEKTDAQESLLRCPHALGMFCKDIH PSLGPLWISQPRATRPNPAELVQRDRRGGGAEELLTGLQYSRILRRPLQSPRLRTASFSA AGSWQAGALSRMETSEIRARTPPPPPPRRISVCGRNNCVCVRDSLHFQWRFPARLRAPNP AQRSCTDGGSPRLFRRAQGPASFYGAPGTDSGGGGGWGEKTVTLGLARSGACGPLRAAPA PSPLPQPQGSAEEKLLPDVVAHREVGEGQGRSPPPRQFRP NT seq 4263 nt NT seq  +upstreamnt  +downstreamnt atgtctctgcttaaccctgtcctgcaaccccccggggtgaaggcctatctgagccaaggg gagcgcttcatcagatgggatgatgaaacaatagcctccccggttatcctccgtgtggat cccaagggctactacttgtactggacatatcagaataaggagatggagtttctggatatc accagcatccgggacacacgctttgggaagtttgccaagatgcccaagagccagaagctc cgggatgtctttaacatggactttcctgacaacaacttcctgctgaagacgctcaccgtg gtgtctggccccgacatggtggacctcaccttccataacttcgtctcctacaaagagaac gtgggcaaggactgggctgaagatgtcctggctctggccaagcacccgctgatggccaat gcctcccgcagcaccttcctggacaagagcctggtgaaactcaagatgcagctcaacccc gaaggaaagattcctgtgaagaattttttccagatgtttcctgctgaccgcaagcgggtg gaagctgccctcagcgcctgccacctcccaaaaggcaagaatgatgccatcaatcccgag gacttcccagaatccgtctacaagagtttcctcatgagcctttgtcctcggccagaaata gatgagatcttcacttcctaccatgccaaggccaaaccctacatgactaaggagcacctg gccaaattcatcaaccagaaacagcgcgactccaggctcaactccctgctgttcccgctt gcgcggcctgaccaggtgcagggcctcatcgacaagtacgagcccagaggcatcaacgtg cagaggggccagctgtcccccgagggcatggtatggttcctctgcggaccagagaacagc gtgctggcccaggacaagctgctgctgcaccacgacatgacgcagccgctcaaccattac ttcatcaactcctcccacaacacctacctgacagccggccagttctcaggcctttcctct gccgagatgtaccgccaggtgctgctggcgggctgccgctgcgtggagctggactgctgg aaggggaagccccctgacgaggagcccatcatcacccacggcttcaccatgaccacagac atctatttcaaggaagcaattgaagctattgcagaaagtgcctttaagacctccccttat ccggtcatcctgtcgtttgaaaaccacgtggactcaccccgccaacaggctaagatggcc gagtactgccgaacgatatttggggatatgctgctcacagagccactggaaaagtttcca ctgaaaccaggcatccccctgcccagccctgaggatctccgaggcaagatcctcatcaag aacaagaagaagcagttttctggtcccccagcccccagccaggagccgggtggggaggct gaggggagcggcccacccaatgtccctgtgggtgaggacacagtgtgggctggtgaggaa ggggccgagctggaggaggaggaggtggaagaggaagaggaggagtcgggaagcctggat gaagaagggatgaaggagatgcagtcagatgagggcacagcgggcctggaggtgacggct tacaaggagatgtccagcctagtcaactacgtccaacccaccaagttcatctccttcgag tcctctgcccagaagaaccgaagttatgtcatttcctccttcacggagctcaaggcttac gacctgctctccaagtcctcagtgcagtttgtggactacaacaagcgccagatgagccgc atctaccccaagggcacccgcatggactcctccaactacatgccccagatgttctggaat gctggttgccagatggttgccctcaacttccagacgatggacctgcccatgcagcagaac atggcgctctttgagttcaatgggcagagtggctacctcctcaagcacgagttcatgcgt cggttagacaagcagttcaaccccttctcggtggaccgcatcgacgtggtggtagccacc accctttccattacggtgatctctgggcagttcctgtcagaacgcagcgtgcgcacctat gtggaagtggagctgtttggccttcctggggactccaagaggcgctatcgcaccaagctg tcacccagtaccaattccatcaatcctgtctggaaggaggagccctttgtctttgaaaag atcttgatgcctgagctggcctccctcagggtggctgtgatggaggacggcaacaagttt cttggacaccgcataatccccatcaatgccctgaattctggataccaccatctgtgcctg cacagcgagagcaacatgccgctcaccatgcctgcactctttgtcttcctggagatgaag gactatgtacctgacacctgggcagatctcacggtggccctcgccaatcccatcaagttc ttcagtgcccatgataagaagtctgtgaagctcaaggaagccatgggaggcctgcctgag aatcccttccctctcgggagtccagttgcctgccaggtcaatgcggcatcagctccaacg agcaacgggtcagcagcagccggggccaaggccagggaggaggccacgaaagaagctgcg gagccgcggaccgccagcgtggaggagctgcgggagctgaagggcgtcgtgaagctgcag cggcggcacgagaaggagctgcgggagctggagcggcgcggcgcgcggcgctgggaggag ctgctgcagaggggcgcagcgcagcgggccgagctccggccgccgggcgctgggggcggc ggcgacgtccggggccgcaagctcggcccggggaaaggctcccgcaaaaagaggaccccg ccgggcgaggaccccgccggggcggtgccggccgaaggccccgagggcgcgggcgcgcgt ctgcgagagctgagggacaggctggagctggagctgctgcagcagggcgaggagcagtgc gagtgtgtcctgaggtgcagggcgcagcaagtggccgagcaaatgaccaagatgatggag ctggccagagagaaacaggctgcagagctgaagatcctcaaggagactttggagactgac accaaggaggtgaagaaaaagctggaggccaagaggctggatcggatccaggccatgatg aaggtcaccacagacaagatggctcaggagaggttgaagagagagattaacaactcccat atccaggaggtggtgcaggtcatcaagcagatgacggagaacctggagaatcaccaggag aagctggaagagaagcaggcagcctgcctggaacagatccgggagatggaaaagcagttc cagcaggaggcgctggcacagtacgaggccaagatgaagggcctggaggtggaagtgaag gagtcggtgaggacctacctcagggcctgcttgccctctgtggaggaggacaagcctgag aggccctgcagggtctccagagagctgtgtgagcaggatgcactcacagagaagacagat gcccaggagagcctcctccgatgcccccatgcccttgggatgttctgcaaagacattcac ccttctctgggacctctctggatctcccagccacgtgccaccaggcccaaccctgctgag ctggtgcaacgtgacaggcggggaggcggcgccgaggagttgctaacggggctgcagtac tcccggatcttaaggcgcccgctccagtcgccgcgtctccgcaccgccagcttctcagcc gccgggagctggcaggcgggcgcgttgtctcggatggagacgtccgagatacgagcgcgc actcccccaccgccacccccgcgccgaatcagcgtgtgcgggaggaacaattgtgtgtgc gtgcgtgattcgctacacttccagtggcggttcccagccagactgagagcccccaacccc gcgcagcgtagctgcaccgatgggggcagccctcgtctttttcgacgggctcagggtccc gccagtttctatggagccccgggcaccgactccggtgggggcggagggtggggagagaag actgtgactttgggattggcccggtcgggtgcatgtggccccctgcgagcagcccccgcc ccgtccccgctgccgcagccccagggaagcgcggaggagaagctgctccccgacgtcgtg gcccaccgagaggtgggtgaaggtcaggggcggtctccgccgccccgtcagtttcggccc tga

DBGET integrated database retrieval system