KEGG   Lipotes vexillifer (Yangtze River dolphin): 103079766
Entry
103079766         CDS       T03090                                 

Gene name
GRB2
Definition
(RefSeq) growth factor receptor bound protein 2
  KO
K04364  growth factor receptor-bound protein 2
Organism
lve  Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve01521  EGFR tyrosine kinase inhibitor resistance
lve01522  Endocrine resistance
lve04010  MAPK signaling pathway
lve04012  ErbB signaling pathway
lve04014  Ras signaling pathway
lve04062  Chemokine signaling pathway
lve04068  FoxO signaling pathway
lve04072  Phospholipase D signaling pathway
lve04150  mTOR signaling pathway
lve04151  PI3K-Akt signaling pathway
lve04380  Osteoclast differentiation
lve04510  Focal adhesion
lve04540  Gap junction
lve04550  Signaling pathways regulating pluripotency of stem cells
lve04630  JAK-STAT signaling pathway
lve04650  Natural killer cell mediated cytotoxicity
lve04660  T cell receptor signaling pathway
lve04662  B cell receptor signaling pathway
lve04664  Fc epsilon RI signaling pathway
lve04714  Thermogenesis
lve04722  Neurotrophin signaling pathway
lve04910  Insulin signaling pathway
lve04912  GnRH signaling pathway
lve04915  Estrogen signaling pathway
lve04917  Prolactin signaling pathway
lve04926  Relaxin signaling pathway
lve04935  Growth hormone synthesis, secretion and action
lve05034  Alcoholism
lve05160  Hepatitis C
lve05161  Hepatitis B
lve05163  Human cytomegalovirus infection
lve05165  Human papillomavirus infection
lve05200  Pathways in cancer
lve05203  Viral carcinogenesis
lve05205  Proteoglycans in cancer
lve05206  MicroRNAs in cancer
lve05210  Colorectal cancer
lve05211  Renal cell carcinoma
lve05213  Endometrial cancer
lve05214  Glioma
lve05215  Prostate cancer
lve05220  Chronic myeloid leukemia
lve05221  Acute myeloid leukemia
lve05223  Non-small cell lung cancer
lve05224  Breast cancer
lve05225  Hepatocellular carcinoma
lve05226  Gastric cancer
lve05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:lve00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103079766 (GRB2)
   04012 ErbB signaling pathway
    103079766 (GRB2)
   04014 Ras signaling pathway
    103079766 (GRB2)
   04630 JAK-STAT signaling pathway
    103079766 (GRB2)
   04068 FoxO signaling pathway
    103079766 (GRB2)
   04072 Phospholipase D signaling pathway
    103079766 (GRB2)
   04151 PI3K-Akt signaling pathway
    103079766 (GRB2)
   04150 mTOR signaling pathway
    103079766 (GRB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103079766 (GRB2)
   04540 Gap junction
    103079766 (GRB2)
   04550 Signaling pathways regulating pluripotency of stem cells
    103079766 (GRB2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    103079766 (GRB2)
   04660 T cell receptor signaling pathway
    103079766 (GRB2)
   04662 B cell receptor signaling pathway
    103079766 (GRB2)
   04664 Fc epsilon RI signaling pathway
    103079766 (GRB2)
   04062 Chemokine signaling pathway
    103079766 (GRB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    103079766 (GRB2)
   04912 GnRH signaling pathway
    103079766 (GRB2)
   04915 Estrogen signaling pathway
    103079766 (GRB2)
   04917 Prolactin signaling pathway
    103079766 (GRB2)
   04926 Relaxin signaling pathway
    103079766 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    103079766 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    103079766 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103079766 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    103079766 (GRB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103079766 (GRB2)
   05206 MicroRNAs in cancer
    103079766 (GRB2)
   05205 Proteoglycans in cancer
    103079766 (GRB2)
   05203 Viral carcinogenesis
    103079766 (GRB2)
   05231 Choline metabolism in cancer
    103079766 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    103079766 (GRB2)
   05225 Hepatocellular carcinoma
    103079766 (GRB2)
   05226 Gastric cancer
    103079766 (GRB2)
   05214 Glioma
    103079766 (GRB2)
   05221 Acute myeloid leukemia
    103079766 (GRB2)
   05220 Chronic myeloid leukemia
    103079766 (GRB2)
   05211 Renal cell carcinoma
    103079766 (GRB2)
   05215 Prostate cancer
    103079766 (GRB2)
   05213 Endometrial cancer
    103079766 (GRB2)
   05224 Breast cancer
    103079766 (GRB2)
   05223 Non-small cell lung cancer
    103079766 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    103079766 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    103079766 (GRB2)
   05160 Hepatitis C
    103079766 (GRB2)
   05163 Human cytomegalovirus infection
    103079766 (GRB2)
   05165 Human papillomavirus infection
    103079766 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103079766 (GRB2)
   01522 Endocrine resistance
    103079766 (GRB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:lve04131]
    103079766 (GRB2)
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified [BR:lve04990]
    103079766 (GRB2)
Membrane trafficking [BR:lve04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    103079766 (GRB2)
Domain-containing proteins not elsewhere classified [BR:lve04990]
 Src homology (SH) domain-containing proteins
  Signal transducing adaptor proteins
   103079766 (GRB2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH2_2 SH3_3 DUF5093 hSH3 SH3_4
Other DBs
NCBI-GeneID: 103079766
NCBI-ProteinID: XP_007454410
UniProt: A0A340X5P7
LinkDB
Position
Un
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagctaccgcagacgacgagctgagcttcaaa
aggggggacatcctcaaggttttgaatgaagaatgtgatcagaactggtacaaggcagag
ctcaatgggaaagacggcttcatccccaagaattacatagaaatgaaaccacatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgcttagcaaacagcggcacgat
ggggcctttcttatccgagagagcgagagtgctcctggggatttctccctctctgtcaag
tttggaaatgatgtacagcacttcaaggtgctccgagatggggctggaaagtatttcctc
tgggtggtcaagttcaattctttgaatgagctggtagattatcacagatctacatccgtc
tccagaaaccagcagatatttctccgggacatagagcaggtgccacagcaaccgacgtac
gtccaagccctctttgactttgatccccaagaggatggagagctgggattccgtcgggga
gactttatccacgtcatggataactcagaccccaactggtggaaaggggcttgccacggg
cagaccggcatgtttccacgcaattatgtcacccccgtgaaccggaacgtctaa

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