KEGG   Lipotes vexillifer (Yangtze River dolphin): 103083056Help
Entry
103083056         CDS       T03090                                 

Gene name
DOT1L
Definition
(RefSeq) DOT1 like histone lysine methyltransferase
  KO
K11427  histone-lysine N-methyltransferase, H3 lysine-79 specific [EC:2.1.1.43]
Organism
lve  Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve00310  Lysine degradation
lve05202  Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:lve00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    103083056 (DOT1L)
 09160 Human Diseases
  09161 Cancers
   05202 Transcriptional misregulation in cancers
    103083056 (DOT1L)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:lve03036]
    103083056 (DOT1L)
Enzymes [BR:lve01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.43  histone-lysine N-methyltransferase
     103083056 (DOT1L)
Chromosome and associated proteins [BR:lve03036]
 Eukaryotic Type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     103083056 (DOT1L)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: DOT1 HALZ
Motif
Other DBs
NCBI-GeneID: 103083056
NCBI-ProteinID: XP_007460496
LinkDB All DBs
Position
Un
AA seq 1799 aa AA seqDB search
MASPPPPAFIRTVPRPRPPTPRERGRTREWGLQEAQARPPLSASDWQKAPRRSSAGARRG
RGRRGVGNARRAPRRGPPRPAPPRLSPQPGLGAGACRCARFRGTGGGYVSAKLELRLKSP
VGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQ
RLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVTDPEKLNNYEPFS
PEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPA
KYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQ
LKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSY
YLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKLPESKAAMPADTPM
DSGAEEEKAGATTVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSTANPERKPKKTQSA
LDLLHAQTVSRAASPSPQVESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNARLLGAA
QQLLGHCRAQREETRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQTEQLEKGN
RELRSQSLRLLKARCEELKLDWSTLSLEGLLKEKQALKSQISEKQRHCLELQISIVELEK
SQRQQELLQLKSCVPPDDALSLHLRGKGGLGREPEAEPGRPHLELDCARFSLPHLSNMSP
ELSMNGHAASYELCGALSRPSPKQNTPQYLASPLDQEVVPCTPNHSGRPRLEKLSGLALP
DYTRLSPAKLVLRRHLSQDHTANSRATASELHPRAEHAKENGLPYQSPGIANGIKLSPQD
PRPSSPAALQMTGEKGSEKGLKERTYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVV
LPSRAEKVRSTPSPVPQARESLSTLEKQMGAGTHGSGGSAAGSRSLTLAPAGFAYAGSVA
ISGALAGSPVPLVSGAEPPALDESSSSGSLFATVGSRSSTPQHPPLLAQPRNCGSASPTP
QLCASPRLGAQGPLPDTSKGDLPSEAGFSDPESEAKRRIVFTISAGSSSAKQSPSSKHSP
LSSGARGDGGQSHGQDSRKRGRRKRAAAGTPGLSSGVSPKRRALPSVAGLFTQSSGSPLN
LNSMVSNINQPLEITAISSPESSLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSD
EEQGSEDEPGSARIERKIATISLESKSPPKTLENGGGLAGRKVLASEPVNSSKWKSTFSP
ISDLGLAKAADSPLQAASALSHNSLFAFRPGLEEPGAADAKLAAHPRKSFPGALPGAGGL
SPSSHPASSFALGGGLAADLSLHSFSDGASLSHKAPEVAGLGTPLSFPGPRGKEGGAAEP
GPFVNKRQLDGLAPKGEGGPPVCGPADKASATHGKAGKGRDREPDVKNGHNLFMAAAAAA
AAAAAAAPPSGGLLSGPGLAPAVSSAGGTAPSAQTHRPFLGAFAPGPQFALGPMSLQANL
GPSVLQSLFSSVPAAGLVHVSTAAPRLTNSHAMGSFSSGVAGGAVGGAFNHAVPPASAHP
FGASFGSGAACRSATLSLTPLQAVASPPASSFQAPPPAEPRPPPPPPHLGRPPPGPPALH
APPPPNAALPPPPALLPANSEPVLLQNLASLPANQAFLPAASAASVPPANASLSIKLASL
PHKVSRPSFTVHHPPLPGLALAQAAPVIPQASSTGPPAVWVSLGMPPPYAARLAGVKPR
NT seq 5400 nt NT seq  +upstreamnt  +downstreamnt
atggcgtctccgcctccgcccgcctttatacgcacagtgcccaggccacgccccccaacg
ccgcgggaacgcggccgcacgagggagtggggccttcaagaagcccaggcgcgcccgccc
ctctcggcgtctgattggcagaaggctccccgtcgtagctctgcgggcgcgcggaggggg
cggggccggcgtggcgtcgggaacgcgcgccgcgcgccgcgacgcggcccgccccgcccc
gccccgccccgcctctccccgcagccgggcctgggggccggggcgtgtcgctgtgcccgc
tttcgggggactggcggtggctacgtctccgcgaagctggagctgaggctcaagtcgccc
gtgggggctgagcccgccgtctacccgtggccgctgccggtctacgacaaacaccacgat
gctgctcatgaaatcatcgagaccatccggtgggtctgtgaagaaatcccagatctcaag
ctcgctatggagaattatgttttaatcgactacgacaccaaaagcttcgaaagcatgcag
aggctctgtgacaagtacaaccgggccatcgacagcatccaccagctgtggaagggcacc
acgcagcccatgaagctgaacacgcggccgtccacgggcctcctgcgccacatcctgcag
caggtctacaaccactcggtgaccgaccccgagaaactcaacaactatgagcccttctcc
ccggaggtgtacggggagacttccttcgacctggtcgcccagatgatcgacgagatcaag
atgaccgaggacgacctgtttgtggacctgggtagcggagtgggccaggttgtgctgcag
gtcgctgcggctaccaactgcaaacatcactatggtgtcgagaaagctgacatcccggcc
aagtacgcggagaccatggaccgagagttcaggaagtggatgaaatggtatggaaaaaag
catgcagaatacacactggagagaggagatttcctctcggaagagtggagagagcggatc
gctaacacgagtgttatatttgtgaataactttgcctttggtcctgaggtggatcaccag
ctgaaggagcggtttgcaaacatgaaggaaggtggcagaattgtgtcctcgaagcccttt
gcacctctgaacttcagaataaacagtagaaacttgagtgacatcggcaccatcatgcgc
gtcgtggagctgtcgccgctaaaaggctcggtgtcgtggacggggaagccggtgtcttac
tacctgcacaccatcgaccgcaccatacttgaaaactatttttctagtctgaaaaatcca
aaactcagggaggaacaagaggcagctcggcgccggcagcagcgggagaacaagagcaat
acgaccacccccaccaagctgcccgagagcaaggcggccatgcccgccgacacccccatg
gactctggtgctgaggaagagaaagccggggcgaccactgtcaagaagccatctccctcc
aaggcccggaagaagaagctgaacaagaagggccggaagatggccggccggaagcgcgga
cgccccaagaagatgagcaccgccaaccctgagcgcaagcccaagaagacccagagcgcg
ctggacctgctgcacgcccagaccgtgtcgcgggcggcgtcaccctcgccgcaggtagaa
tccttcaagattcagtacctacagttcctggcgtacacaaagacccctcagtacaaggcc
aacctgcagcagctgctggaccaggagaaggagaagaacgcccggttgctgggtgccgcg
cagcagctgctcggccactgccgagctcagagggaggagaccaggaggctcttccagcag
aaactcgatgagctgggagtgaaggcgctgacctacaacgacctgatccaagcgcagaag
gagatctcggctcacaaccagcagctgagggagcagacggagcagctggagaagggcaac
cgggagctgaggagccagagcctgcggctgctcaaggcacggtgcgaggagctgaagctg
gactggtccacgctgtccctggagggcctgctgaaggagaagcaggccctgaagagccag
atctcggagaagcagaggcactgcctggagctgcagatcagcattgtggagctggagaag
agccagcgacagcaggagctcctgcagctcaagtcctgcgtgccgcccgacgacgccctg
tctctgcacctgcgcgggaagggtggcctgggccgagagccagaggccgagcccggccgg
ccacacctggagctggactgcgccaggttctccctaccccacttgagcaacatgagcccg
gagctgtccatgaacggccacgcggccagctatgagctctgcggcgcactgagccggccc
tcacccaagcagaacaccccccagtacctggcctcccccctggaccaggaggtcgtgccc
tgcaccccgaaccacagtggccggccgaggctcgagaagttgtccggcctggccctgccc
gactacaccaggctctccccggccaagctggtgctgcggcgccacctgagccaggaccac
acagccaacagcagggcgaccgccagcgagctgcacccacgagctgaacatgccaaggag
aacggcctcccgtaccagagccccggcatcgccaacggcatcaaactgagcccacaggac
cctcggccctcgtcccctgcggccttgcagatgacgggagagaagggcagtgagaagggt
ttgaaggagcgcacctacgccagcagtggggaggccatcaccagcctgcccgtcagcatc
ccgctcagcaccgtgcagcctagcaagctgccagtcagcatccccctggccagcgttgtg
ctgcccagccgcgccgagaaggtgagaagcacccccagccccgtgccgcaggcccgagag
tccttgtccacactggagaagcagatgggtgctggcacccacggctccgggggcagcgct
gctgggagcagaagcctcaccctggcccctgcaggctttgcctacgccggctcagtggcc
atcagtggggccctggcagggagcccggtaccgctcgtctctggagctgagccccccgcc
ctggatgagtcctcgagctccggaagcctctttgccactgtggggtcccgcagctccacc
cctcagcatccccccctgctggcacagccccgcaactgcggctcggcctcgcccaccccc
cagctctgcgccagtcccaggctcggcgcccagggcccgctccccgacaccagcaaagga
gacctgccctctgaggccggcttctcggatcccgagagtgaagccaagagaaggatcgtc
ttcaccatctcggccggctctagcagcgccaagcagtcaccttccagcaagcacagccct
ctgtcctcgggtgcccgcggtgatggcggccagagccacgggcaggacagccgcaagagg
ggcaggaggaagcgggcggcggcggggacccccggcctcagctcgggcgtgtcccccaag
cgccgggccctgccgtccgtcgccggcctcttcacgcagtcttcagggtcccccctgaac
ctcaactccatggtcagcaacatcaaccagcccttggaaatcacggccatctcgtccccc
gagagctccctgaagagctcgcctgtcccttaccaggacaacgaccagccgcccgtgctc
aagaaggagaagcccctgagccagaccaacggggcccactattccccgctgacctcagat
gaggagcagggctctgaggacgagcccggcagtgccagaattgaaagaaaaattgcaaca
atctccttagaaagcaaatctcctccgaaaaccttggaaaatgggggcggcctggcggga
aggaaggtgctggccagcgagccggtcaacagcagcaagtggaagtccaccttctcgccc
atctccgacctcggcctggccaaggcagccgacagcccgctgcaggccgcctccgctctg
agccacaactccctgttcgctttccggcccggcctggaggaacctggcgcggctgatgcc
aagctggctgcccaccccaggaagagcttcccaggcgcgctgccgggggcgggcgggctg
agccccagcagccatcccgccagcagcttcgccctgggcgggggcctggcggccgacctc
agtttacacagcttcagcgatggtgcttctctctcccacaaggcccccgaggtggccggc
ctgggcacccccctgagctttcccggcccgcggggcaaggagggcggcgccgcagagccc
ggccccttcgtgaacaagaggcagctggacggactggccccgaagggcgaggggggccca
cctgtgtgtgggcccgcggacaaggcctcagcgacgcacggcaaggcgggcaagggccgt
gatcgcgagcccgacgtcaagaacggccacaacctcttcatggctgccgcggctgctgcc
gccgccgccgccgccgccgcccccccctccgggggcctcctcagcggcccgggccttgcc
ccggcagtgtcctcggcagggggcacggccccgtccgcccagacccaccgccccttcctg
ggcgccttcgcccccggcccgcagttcgcactgggccccatgtccctgcaggccaacctg
ggcccgtccgtgctgcagtccctgttcagctccgtgcccgccgccggcctggtgcacgtc
tcaaccgccgcccccagactgaccaactcgcacgccatgggcagcttctcctccggggtg
gccggcggtgcagtcggaggtgcctttaaccacgcggtgcctcccgcctccgctcatccg
tttggagccagtttcggcagtggggctgcatgtcgcagcgccacgctgagcctaaccccg
ctgcaggcggtggccagcccccccgcctcttcctttcaggccccgccccctgcggagccg
aggccgcccccgccccctccgcacctgggccggccccctccggggccgcccgccctccac
gccccgccccctcctaacgccgccttgcctccgccccccgcgctgctcccggctaactct
gagcccgtgctcctgcagaacctcgcgtccctcccagctaaccaagctttcttacctgcc
gcctctgctgcctctgtgccgcctgctaacgcctctctgtccatcaagctcgcctcactt
ccgcacaaggtgtcccgcccctccttcacggtgcaccacccgcccctgcccgggctggcc
ctggcccaggccgcgcccgtgatcccgcaggccagctccacggggccgcccgccgtgtgg
gtttcccttggcatgccacctccgtatgccgcgcgccttgcgggggttaagccgcgataa

DBGET integrated database retrieval system