KEGG   Lipotes vexillifer (Yangtze River dolphin): 103087340
Entry
103087340         CDS       T03090                                 

Gene name
CACNA1C
Definition
(RefSeq) calcium voltage-gated channel subunit alpha1 C
  KO
K04850  voltage-dependent calcium channel L type alpha-1C
Organism
lve  Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve04010  MAPK signaling pathway
lve04020  Calcium signaling pathway
lve04022  cGMP-PKG signaling pathway
lve04024  cAMP signaling pathway
lve04260  Cardiac muscle contraction
lve04261  Adrenergic signaling in cardiomyocytes
lve04270  Vascular smooth muscle contraction
lve04713  Circadian entrainment
lve04720  Long-term potentiation
lve04723  Retrograde endocannabinoid signaling
lve04724  Glutamatergic synapse
lve04725  Cholinergic synapse
lve04726  Serotonergic synapse
lve04727  GABAergic synapse
lve04728  Dopaminergic synapse
lve04742  Taste transduction
lve04911  Insulin secretion
lve04912  GnRH signaling pathway
lve04921  Oxytocin signaling pathway
lve04924  Renin secretion
lve04925  Aldosterone synthesis and secretion
lve04927  Cortisol synthesis and secretion
lve04929  GnRH secretion
lve04930  Type II diabetes mellitus
lve04934  Cushing syndrome
lve04935  Growth hormone synthesis, secretion and action
lve05010  Alzheimer disease
lve05020  Prion disease
lve05022  Pathways of neurodegeneration - multiple diseases
lve05031  Amphetamine addiction
lve05410  Hypertrophic cardiomyopathy
lve05412  Arrhythmogenic right ventricular cardiomyopathy
lve05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:lve00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103087340 (CACNA1C)
   04020 Calcium signaling pathway
    103087340 (CACNA1C)
   04024 cAMP signaling pathway
    103087340 (CACNA1C)
   04022 cGMP-PKG signaling pathway
    103087340 (CACNA1C)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    103087340 (CACNA1C)
   04929 GnRH secretion
    103087340 (CACNA1C)
   04912 GnRH signaling pathway
    103087340 (CACNA1C)
   04921 Oxytocin signaling pathway
    103087340 (CACNA1C)
   04935 Growth hormone synthesis, secretion and action
    103087340 (CACNA1C)
   04924 Renin secretion
    103087340 (CACNA1C)
   04925 Aldosterone synthesis and secretion
    103087340 (CACNA1C)
   04927 Cortisol synthesis and secretion
    103087340 (CACNA1C)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    103087340 (CACNA1C)
   04261 Adrenergic signaling in cardiomyocytes
    103087340 (CACNA1C)
   04270 Vascular smooth muscle contraction
    103087340 (CACNA1C)
  09156 Nervous system
   04724 Glutamatergic synapse
    103087340 (CACNA1C)
   04727 GABAergic synapse
    103087340 (CACNA1C)
   04725 Cholinergic synapse
    103087340 (CACNA1C)
   04728 Dopaminergic synapse
    103087340 (CACNA1C)
   04726 Serotonergic synapse
    103087340 (CACNA1C)
   04720 Long-term potentiation
    103087340 (CACNA1C)
   04723 Retrograde endocannabinoid signaling
    103087340 (CACNA1C)
  09157 Sensory system
   04742 Taste transduction
    103087340 (CACNA1C)
  09159 Environmental adaptation
   04713 Circadian entrainment
    103087340 (CACNA1C)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    103087340 (CACNA1C)
   05020 Prion disease
    103087340 (CACNA1C)
   05022 Pathways of neurodegeneration - multiple diseases
    103087340 (CACNA1C)
  09165 Substance dependence
   05031 Amphetamine addiction
    103087340 (CACNA1C)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    103087340 (CACNA1C)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    103087340 (CACNA1C)
   05414 Dilated cardiomyopathy
    103087340 (CACNA1C)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    103087340 (CACNA1C)
   04934 Cushing syndrome
    103087340 (CACNA1C)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:lve04040]
    103087340 (CACNA1C)
Ion channels [BR:lve04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   103087340 (CACNA1C)
SSDB
Motif
Pfam: Ion_trans CAC1F_C GPHH Ca_chan_IQ PKD_channel Glyco_hydro_cc
Other DBs
NCBI-GeneID: 103087340
NCBI-ProteinID: XP_007469545
UniProt: A0A340YDP1
LinkDB
Position
Un
AA seq 2112 aa
MNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKP
KKQGSTMATRPPRALLCLTLKNPIRRACISIVEWKYPLPFEIIILLTIFANCVALAIYIP
FPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVG
LFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMV
PLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQC
QNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFV
SLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAED
IDPENEDEGLDEEKPRNMSMPTSETESVNTENVAGGDIEGESCGARLAHRISKSKFSRYW
RRWNRFCRRKCRAAVKSSAFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLAL
FTAEMLLKTYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKVMSPLGISVLRCVRLLR
IFKITRYWNSLGNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRR
STFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLN
VFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPQKRQEAVEKPAVEETEEKIELK
SITADGGSPPATKINMDDLQPNENEDKSSYPNLETTGEEEEEPEMPVGPRPRPLSELHLK
EKAAPMPEASAFFIFSPSNRFRLQCHRVVNDSVFTNLILFFILLSSISLAAEDPVQHTSF
RNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRSCFNILDLLVVSVSLISFGIQS
SAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGV
QLFKGKLYTCSDSSKQTEAECKGNYVTYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMAL
FTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISVFFIIYIIIIAFFMMNIFVGFVIVT
FQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVL
ILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDC
LIVIGSVIDVILSETNPAEHTQCSPFMNAEENARISITFFRLFRVMRLVKLLSRGEGIRT
LLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLL
LFRCATGEAWQDVMLACMPGKKCAPGAEPGGSAEGEAPCGSSFAVFYFISFYTLCAFLII
NLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPL
GFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAI
IKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPARRNA
LSLQAGLRTLHDLGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVG
YYPSDSRSTFPQTFTTQRPLHISKAGTSQGDAESPSHEKLVDSTFIPSSYSSMGSNANIN
NANNTALGRCPCPAGQPGAVSVSTVEGRGPPLSPAVQVQGASWRLSSKRCPSRDSLIAMV
CQDEAPRDETCDLRMDEDAEYGSEPSLICTEMLSYQDDENRQLAPPEEDRRDIHLSPKRG
FLRSASLGRRASFHLECLKRQKNPGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHPPG
ALPPPPATPPATPGPAWPPRPVPTLQLEGAESSDKLTGSFPSVHCGPWAGEPTPCGAGGG
IRRARPVSLTVPSPAGPRGRPFHGSASSLVEAVLISEGLGQFAQDPRFLEATTQELADAC
DMTIEEMESAADNILSGGARQSPNGTLLPCANCRDPGPDREGGAEDAAWAPSPEPRQGGE
EPRDSRAFASSL
NT seq 6339 nt   +upstreamnt  +downstreamnt
atgaatgccaatgcggccgcggggctggcacctgagcacatccccacaccgggggccgcc
ctgtcctggcaggcagccattgacgcggcccggcaggccaagctgatgggcagcgctggc
aacgccaccatctccacggtcagctccacgcagcggaagcggcagcagtacgggaagccc
aagaaacagggcagcacgatggccacccgcccgccccgtgccctgctctgcctgaccctc
aagaaccccatccggagggcgtgcatcagcatcgtcgagtggaaatatcctttgccattt
gaaatcattattttactgacaatttttgccaactgtgtggccttagcgatctatattccc
tttccagaggacgactccaacgccaccaactccaacctggaacgggtggagtatctcttc
ctcatcatttttactgtggaagcatttttaaaagtcatagcctatgggctgctcttccac
cccaatgcttacctccgcaacggctggaacttgctggattttatcattgtggttgtcggg
cttttcagtgcaatcttagagcaagccaccaaagccgacggggccaacgccctgggaggg
aagggggctggatttgacgtgaaggcgctcagggcgttccgcgtgctgcggcccctacgg
ctggtgtccggggtcccgagtctccaggtggttctgaactccatcatcaaggctatggta
cccctgctgcacatcgctctgcttgtgctctttgtcattatcatctacgccatcatcggg
ctggagctcttcatggggaagatgcacaagacctgctacaaccaggagggcatcgcagat
gtcccagcagaagacgacccctccccctgtgccctggagacgggccacgggcggcagtgc
cagaacggcacggtgtgcaagccgggctgggatgggcccaagcacggcatcaccaacttc
gacaactttgcttttgccatgctgaccgtgttccagtgcatcaccatggagggctggacc
gacgtcctctactggatgcaggacgctatgggctacgagttaccctgggtgtattttgtc
agtctggtcatctttggatcctttttcgttctaaatctggttcttggtgtgttgagcgga
gagttctccaaggagagagagaaggccaaggcccggggcgacttccagaagctgcgggag
aagcagcagctggaagaggacctgaagggctacctggactggatcacgcaggcggaggac
atcgaccccgagaacgaggacgagggcttggacgaggagaaaccccgaaacatgagcatg
cccaccagtgagaccgagtctgtcaacaccgaaaacgtggctggaggtgacatcgaggga
gagagctgtggggccaggctggcccacaggatctccaagtcgaagtttagccgctactgg
cgccggtggaatcgcttctgcaggaggaagtgccgcgcggccgtgaagtcgagcgccttc
tactggcttgtcatcttcctggttttccttaacacgctcaccatcgcctctgagcactac
aaccagccccactggctcacggaagtccaagacacggccaacaaggcgctgctggccctg
ttcacggccgagatgctgctcaagacgtacagcctggggctgcaggcctacttcgtgtct
ctcttcaaccgcttcgactgcttcgtcgtgtgcggcggcatcctggagaccatcctggtg
gagaccaaggtcatgtcgccgctgggcatctccgtgctgagatgcgtacgcctcctgagg
atatttaagatcacgaggtactggaactccctgggcaacctggtggcttccctgctgaac
tctgtgcgctccatcgcctccctgcttctgctgctgtttcttttcatcatcatcttctcc
ctcctgggcatgcagctcttcggggggaagttcaactttgatgagatgcagacccggagg
agcacgttcgataacttcccccagtccctcctcaccgtgtttcagatcctgaccggggag
gactggaattcggtgatgtatgatgggatcatggcttatggcggcccctcttttccaggg
atgttggtctgtatttacttcatcatcctcttcatctgtggaaattatatcctactgaat
gtgttcttggccattgccgtggacaacctggctgacgccgagagcctcacctcggcccag
aaggaggaggaagaggagaaggagaggaagaaactggccaggactgccagcccccagaag
agacaagaggcggtggagaagccggccgtggaggagaccgaggagaaaatcgagctgaaa
tccatcactgcggatggagggtcccctcctgccaccaagatcaacatggacgacctccag
cccaacgagaatgaagacaagagttcctaccccaacctggaaaccacaggagaggaagag
gaggagcctgagatgcccgtgggcccccgcccccgccccctctctgagctgcacctgaag
gagaaggcggcgcccatgccagaagccagcgccttctttatcttcagcccgagcaacagg
ttccgcctccagtgccatcgcgtcgtcaacgactccgtcttcaccaacctgatcctgttc
ttcatcctgctcagcagcatctccctggcggccgaggaccccgtccagcacacgtccttc
aggaaccacattctgttttattttgacattgttttcactaccattttcaccattgaaatt
gctctgaagatgaccgcctacggggccttcctgcacaagggctccttctgccgcagctgc
ttcaatatcctggacctgctggtggtcagcgtgtccctcatctccttcggcatccagtcc
agtgccatcaacgtggtgaagatcttgcgggtcctgagggtgctgaggcccctgagggcc
atcaacagggccaaggggctgaagcacgtggtgcagtgcgtgttcgtggccatccgcacc
atcgggaacatcgtgatcgtcaccacgctgctccagttcatgttcgcctgcatcggggtc
cagctcttcaagggcaagctctacacctgttcggacagttccaaacagacggaggccgaa
tgcaaggggaactacgtcacatacaaggacggggaggtggatcaccccatcatccagccc
cgcagctgggagaacagcaagtttgactttgacaacgtcctggcagctatgatggccctg
ttcaccgtctccacctttgaggggtggccagagctgctgtaccgctccatcgactcccac
acggaggacaagggccccatttacaactaccgcgtggagatctccgtcttcttcatcatc
tacatcatcatcatcgcctttttcatgatgaacatctttgtgggcttcgtcatcgtcacc
ttccaggagcagggggagcaggagtacaagaactgcgagctggacaagaaccagcggcag
tgcgtggagtacgccctgaaggcccggcccctgcggaggtacatccccaagaaccagcac
cagtacaaggtgtggtatgtggtcaactccacctacttcgagtacctgatgttcgtcctc
atcctgctcaacaccatctgcctggccatgcagcactacggccagagctgcctgttcaaa
atcgccatgaacatcctgaacatgctcttcactggcctcttcacggtggagatgattctg
aagctcatcgccttcaagcccaagggctactttagtgacccctggaatgtctttgactgc
ctcatcgtaattggcagcgtaattgacgtcattctcagtgagacgaatccagctgaacat
acccaatgctctccctttatgaacgcagaggagaacgcccgcatctccatcaccttcttc
cgcctcttccgggtcatgcgtctggtcaagctgctgagccgtggggagggcatccggacg
ctgctgtggacgttcatcaagtccttccaggccctgccctacgtcgccctcctgatcgtg
atgctgttctttatctacgccgtcatcgggatgcaggtgttcgggaaaatcgccctgaat
gacacgacagagatcaacaggaacaacaacttccagaccttcccccaggccgtgctgctg
ctcttcaggtgcgccaccggggaggcgtggcaggacgtcatgctggcctgcatgccgggc
aagaagtgcgcgcccggggcggagccgggcggcagcgccgagggggaggcgccctgcggc
agcagcttcgccgtcttctacttcatcagcttctacaccctgtgcgccttcctgatcatc
aacctcttcgtagctgtcatcatggacaactttgactacctgacaagggactggtccatt
ctgggtccccaccatctggacgaatttaagagaatctgggcggagtatgatcctgaagcc
aagggtcgcatcaaacacctggatgtggtgaccctgctccggaggattcagccccccctg
ggctttgggaagctgtgccctcaccgcgtggcttgcaaacgcctggtctccatgaacatg
cccctgaacagcgacgggacggtcatgttcaacgccaccctgtttgccctggtccggaca
gccctgaggatcaaaacggaagggaacctggaacaggccaacgaggagctgcgggccatc
atcaagaagatctggaagcggaccagcatgaagctgctggaccaggtggtgccgcctgcg
ggagatgatgaggtcacggtgggcaagttttacgctactttcctgatccaagagtatttc
cggaaattcaagaagcgcaaggagcaaggcctggtgggcaagcccgcccggaggaacgcc
ctgtccctgcaggctggtctgcgcaccctgcatgaccttgggcccgagatccgccgggcc
atctccggggacctgaccgccgaggaggagctggacaaggccatgaaggaggctgtgtcc
gcggcctcggaagatgacatcttcaggagggccggcggcctgttcggcaaccacgtgggc
tactaccccagcgacagccggagcaccttcccccagaccttcaccacccagcgccctctg
cacatcagcaaggcgggcaccagccagggcgacgcggagtcgccctcccacgagaaactg
gtggactccaccttcatccccagcagctactcctccatgggttccaacgccaacatcaac
aacgccaacaacactgccctgggccgctgcccctgccctgccggccagcccggtgctgtc
agcgtcagcaccgtggagggccgtgggccccccttgtcccccgctgtccaggtgcagggg
gcttcgtggaggctcagctccaagaggtgcccctcccgggacagcctgatagccatggtg
tgtcaggacgaggcccctcgggatgagacttgtgacctgaggatggatgaggacgccgag
tacggcagtgagcccagcctgatctgcacggagatgctctcctaccaggacgacgagaat
cggcagctggcgccccctgaggaggacaggagagacatccatctctctccaaagaggggc
ttcctgcgctccgcctccctaggtcgaagggcctccttccaccttgagtgtctgaagcga
cagaagaatccagggggagacatctctcagaagacagttctgcccctgcatctcgttcac
catcaggcgctggcggtggcgggcctgagccccctcctgcagagaagccatccccccggc
gccctccccccgccgcctgccacgccccctgccacgcccggcccggcctggcccccgcgg
cctgtgcccaccctgcagctggagggggccgagtccagcgacaagctcaccggcagcttc
ccatccgtccactgcggcccctgggccggggagcccacgccctgcggggccggcggcggc
atccggagggcccggcccgtgtccctcaccgtgcccagcccggcggggccccggggccgg
cccttccacggcagcgccagcagcctggtggaggcggtcctgatctcagaaggactgggg
caatttgctcaggatcccaggttcctcgaggccaccacccaggagctggccgacgcctgc
gacatgaccattgaggagatggagagcgcggccgacaacatccttagcgggggcgcccgg
cagagccccaacggtaccctgctcccgtgtgcaaactgcagggacccggggccagacaga
gaggggggcgcagaggacgcggcctgggcacccagccccgagccccgccagggcggagag
gagccccgggacagcagggccttcgccagcagcctgtag

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