KEGG   PATHWAY: map00280
Entry
map00280                    Pathway                                

Name
Valine, leucine and isoleucine degradation
Class
Metabolism; Amino acid metabolism
Pathway map
map00280  Valine, leucine and isoleucine degradation
map00280

Module
M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:map00280]
M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:map00280]
Disease
H00172  Maple syrup urine disease
H00173  Isovaleric acidemia
H00174  Methylmalonic aciduria
H00175  Propionic acidemia
H00179  3-Hydroxy-3-methylglutaryl-CoA lyase deficiency
H00181  3-Methylcrotonylglycinuria
H00375  SBCAD deficiency
H00754  3-Methylglutaconic aciduria
H00925  2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency
H01076  Alpha-methylacetoacetic aciduria
H01121  Succinyl CoA:3-oxoacid CoA transferase (SCOT) deficiency
H01123  HMG-CoA synthase deficiency
H01279  Isobutyryl-CoA dehydrogenase deficiency
H01349  Methacrylic aciduria
H01364  3-Hydroxyacyl-CoA dehydrogenase deficiency
H01400  Secondary hyperammonemia
H02000  Dihydrolipoamide dehydrogenase deficiency
H02109  Combined malonic and methylmalonic aciduria
H02285  Methylmalonate semialdehyde dehydrogenase deficiency
Other DBs
GO: 0006550 0006552 0006574
Related
pathway
map00020  Citrate cycle (TCA cycle)
map00240  Pyrimidine metabolism
map00290  Valine, leucine and isoleucine biosynthesis
map00522  Biosynthesis of 12-, 14- and 16-membered macrolides
map00640  Propanoate metabolism
map00900  Terpenoid backbone biosynthesis
map01056  Biosynthesis of type II polyketide backbone
KO pathway
ko00280   
LinkDB

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