KEGG   PATHWAY: map07216
Entry
map07216          Drug      Pathway                                

Name
Catecholamine transferase inhibitors
Class
Pathway map
map07216  Catecholamine transferase inhibitors
map07216

Compound
C01108  1,2,3-Trihydroxybenzene
C15474  Tropolone
C15475  U 0521
C15476  Norselegiline
C15477  CGP 28014
D00152  Phloroglucinol (JAN)
D00346  Isoniazid (JP17/USP/INN)
D00505  Phenelzine sulfate (USP)
D00781  Entacapone (JP17/USP/INN)
D00785  Selegiline hydrochloride (JAN/USP)
D00786  Tolcapone (JAN/USP/INN)
D00826  Tranylcypromine sulfate (USP)
D01097  Lazabemide hydrochloride (JAN/USAN)
D01259  Flopropione (JP17/INN)
D01365  Trepibutone (JP17/INN)
D01888  Safrazine hydrochloride (JAN)
D02559  Toloxatone (INN)
D02560  Brofaromine (INN)
D02561  Moclobemide (USAN/INN)
D02562  Rasagiline mesylate (USAN)
D02563  Befloxatone (INN)
D02564  Pargyline hydrochloride (USAN)
D02579  Iproniazid (INN)
D02580  Isocarboxazid (INN)
D03239  Ladostigil tartrate (USAN)
D03241  Nitecapone (INN)
D03248  Clorgiline (INN)
D03731  Selegiline (USAN/INN)
D04681  Lazabemide (USAN/INN)
D08085  Iproniazid phosphate
D08349  Phenelzine (BAN)
D08453  Pargyline (INN)
D08469  Rasagiline (USAN/INN)
D08625  Tranylcypromine (INN)
Reference
  Authors
Sano T, Naito T, Kubo T (eds).
  Title
[Medicinal Chemistry, an Introduction (7th ed)] (In Japanese)
  Journal
Nankodo (2002)
Reference
  Authors
Fukai S.
  Title
[New Drugs Today (6th ed)] (In Japanese)
  Journal
Jiho (1995)
Reference
  Authors
Tanaka C, Kato R (eds).
  Title
[New Pharmacology (4th ed)] (In Japanese)
  Journal
Nankodo (2002)
Reference
PMID:1103160
  Authors
Guldberg HC, Marsden CA.
  Title
Catechol-O-methyl transferase: pharmacological aspects and physiological role.
  Journal
Pharmacol Rev 27:135-206 (1975)
Reference
  Authors
Micek ST, Ernst ME.
  Title
Tolcapone: a novel approach to Parkinson's disease.
  Journal
Am J Health Syst Pharm 56:2195-205 (1999)
DOI:10.1093/ajhp/56.21.2195
Reference
  Authors
.
  Title
Tolcapone: new drug. In Parkinson's disease: unacceptable risk of severe hepatitis.
  Journal
Prescrire Int 15:54-7 (2006)
Reference
PMID:7835624
  Authors
Kaakkola S, Gordin A, Mannisto PT.
  Title
General properties and clinical possibilities of new selective inhibitors of catechol O-methyltransferase.
  Journal
Gen Pharmacol 25:813-24 (1994)
DOI:10.1016/0306-3623(94)90082-5
Reference
PMID:8119326
  Authors
Tornwall M, Mannisto PT.
  Title
Effects of three types of catechol O-methylation inhibitors on L-3,4-dihydroxyphenylalanine-induced circling behaviour in rats.
  Journal
Eur J Pharmacol 250:77-84 (1993)
DOI:10.1016/0014-2999(93)90623-P
Reference
  Authors
Youdim MB, Gross A, Finberg JP.
  Title
Rasagiline [N-propargyl-1R(+)-aminoindan], a selective and potent inhibitor of mitochondrial monoamine oxidase B.
  Journal
Br J Pharmacol 132:500-6 (2001)
DOI:10.1038/sj.bjp.0703826
Reference
  Authors
Youdim MB, Bakhle YS.
  Title
Monoamine oxidase: isoforms and inhibitors in Parkinson's disease and depressive illness.
  Journal
Br J Pharmacol 147 Suppl 1:S287-96 (2006)
DOI:10.1038/sj.bjp.0706464
Reference
  Authors
Mannisto PT, Kaakkola S.
  Title
Catechol-O-methyltransferase (COMT): biochemistry, molecular biology, pharmacology, and clinical efficacy of the new selective COMT inhibitors.
  Journal
Pharmacol Rev 51:593-628 (1999)
Related
pathway
map07027  Antidepressants
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