Mus caroli (Ryukyu mouse): 110284338 Help Entry 110284338         CDS       T05910                                  Gene name Tsc2 Definition (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism mcal  Mus caroli (Ryukyu mouse) Pathway mcal04072   Phospholipase D signaling pathway mcal04115   p53 signaling pathway mcal04140   Autophagy - animal mcal04150   mTOR signaling pathway mcal04151   PI3K-Akt signaling pathway mcal04152   AMPK signaling pathway mcal04211   Longevity regulating pathway mcal04218   Cellular senescence mcal04714   Thermogenesis mcal04910   Insulin signaling pathway mcal04919   Thyroid hormone signaling pathway mcal05163   Human cytomegalovirus infection mcal05165   Human papillomavirus infection mcal05168   Herpes simplex virus 1 infection mcal05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:mcal00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     110284338 (Tsc2)    04151 PI3K-Akt signaling pathway     110284338 (Tsc2)    04152 AMPK signaling pathway     110284338 (Tsc2)    04150 mTOR signaling pathway     110284338 (Tsc2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     110284338 (Tsc2)   09143 Cell growth and death    04115 p53 signaling pathway     110284338 (Tsc2)    04218 Cellular senescence     110284338 (Tsc2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     110284338 (Tsc2)    04919 Thyroid hormone signaling pathway     110284338 (Tsc2)   09149 Aging    04211 Longevity regulating pathway     110284338 (Tsc2)   09159 Environmental adaptation    04714 Thermogenesis     110284338 (Tsc2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     110284338 (Tsc2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     110284338 (Tsc2)    05163 Human cytomegalovirus infection     110284338 (Tsc2)    05165 Human papillomavirus infection     110284338 (Tsc2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:mcal01009]     110284338 (Tsc2) Protein phosphatases and associated proteins [BR:mcal01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      110284338 (Tsc2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Telomere_reg-2 Cnd1 Motif Other DBs NCBI-GeneID:  110284338 NCBI-ProteinID:  XP_021005716 UniProt:  A0A6P7QNL5 LinkDB All DBs Position 17 AA seq 1809 aa AA seqDB search MAKPTSKDSGLKEKFKILLGLGTSRPNPRCAEGKQTEFIITSEILRELSGECGLNNRIRM IGQICDVAKTKKLEEHAVEALWKAVSDLLQPERPPEARHAVLTLLKAIVQGQGDRLGVLR ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELAEFVLQWMDVGLSSEFLLVL VNLVKFNSCYLDEYIASMVHMICLLCIRTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFI ITLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRSYMEDAPLLRGAVFFVG MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRKELQAVTWDI LLDIIERLLQQLQNLDSPELKTIVHDLLTTVEELCDQNEFHGSQERYYELVESYADQRPE SSLLNLISYRAQSIHPAKDGWIQNLQLLMERFFRNECRSAVRIKVLDVLSFVLLINRQFY EEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLS PPPELEERDLAVHSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYESLISHIQLHYKH GYSLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCLCDCTELDRASEKKAS GPLSPPTGPPSPVPMGPAVRLGHLPYSLLFRVLLQCLKQESDWKVLKLVLSRLPESLRYK VLIFTSPCSVDQLSSALCSMLSAPKTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYL DKTRQREMVYCLEQGLIYRCASQCVVALAICSVEMPDIIIKALPVLVVKLTHISATASMA IPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARAPKQGLNNS PPVKEFKESCAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSMAQADDNLKNLHL ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSL LGLDSGDLQGGSDSSSDPSTHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVG VLDTSAPYPPSGPASLGPQTAAAAKPEKPPAGAQLPTAEKTNLAAYVPLLTQGWAEILVR RPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAAGT AKPPTLPRSNTVASFSSLYQPSCQGQLHRSVSWADSAMVLEEGSLGETQVPVEPPELEDF EAALGTDRHCQRPDTYSRSSSASSQEEKSHLEELAAGGIPIERAISSEGARPAVDLSFQP SQPLSKSSSSPELQTLQDILGDLGDKTDIGRLSPEAKVRSQSGILDGEAATWSAAGEESR ITVPPEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDNFKSRAAASSAEKVPGIN PSFVFLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSSSE LAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAV FHIATLMPTKDVDKHRCDKKRHLGNDFVSIIYNDSGEDFKLGTIKGQFNFVHVIITPLDY KCNLLTLQCRKDMEGLVDTSVAKIVSDRNLSFVARQMALHANMASQVHHSRSNPTDIYPS KWIARLRHIKRLRQRIREEVHYSNPSLPLMHPPAHTKVPAQAPTEATPTYETGQRKRLIS SVDDFTEFV NT seq 5430 nt NT seq  +upstreamnt  +downstreamnt atggccaaaccaacaagcaaagattcaggcttgaaggagaagttcaagatactgttggga ttgggaacatcgaggccaaatcccaggtgtgcagaaggcaaacagactgagtttatcatc acatcggaaatcttgagagaactgagtggtgaatgcggcctcaacaatcgcatccgaatg atagggcagatctgtgatgtggcgaaaactaagaagcttgaggagcatgccgtggaggca ctttggaaggctgtctcagacttgctacagccagagcggccaccagaggcccgacatgca gttctcaccttattgaaggccattgtacagggacagggtgatcgtttgggagttctcaga gccctcttcttcaaagtgatcaaggattacccctccaatgaagacctccatgaaaggcta gaagtttttaaggccctcacagacaatgggaggcacattacctatttggaagaagagctg gcagagtttgtcctgcagtggatggatgttggcttgtcctcagaattccttctggtactt gtcaacctggtcaagttcaacagctgttaccttgacgaatacattgcatcaatggttcac atgatttgtctgctatgcatccggacagtgtcctctgtggacattgaggtgtccttgcaa gtgctggatgctgtggtctgctacaactgcctaccagccgagagcctgcctctgttcatt atcaccctgtgccgcaccatcaatgtcaaggagctgtgtgagccttgctggaagctgatg cgtaaccttctgggcacccatctgggccacagcgccatctataacatgtgccgcatcatg gaggacagatcctacatggaagacgccccactgctgagaggagctgtgttctttgtaggg atggcactctggggagctcaccggctctattctctcaagaactcccccacatctgtgctg ccgtctttttatgaggctatgacctgtcccaatgaggtggtgtcatatgagattgttctc tccataacaagactcatcaagaaatataggaaggagctccaggctgtgacatgggatatt ctgctagacatcattgaacgactacttcagcaactccagaacctggacagcccagaactc aagaccatcgtccatgacctgctgaccactgtggaggagctatgtgaccagaacgagttc catggctcgcaggaaagatactatgaactggtggagagctatgcagaccagagacctgaa tcctctctcttaaacttgatatcctacagagcccagtccatccaccccgccaaggatggc tggatccagaacttgcagttgctgatggagaggttcttcaggaatgagtgccgcagcgcc gtgcgcatcaaggtgttggatgttctgtccttcgtgctgctgatcaacaggcagttctat gaggaggagctgattaactcggtggtcatctcacagctctcccacattcccgaggataaa gaccatcaggtccgaaagctggctactcagctgctggtggacctggcagagggctgccac acccaccacttcaacagtctgctggacatcattgaaaaggtgatggcgcgctcactgtct ccacccccggagctggaagaaagggacctggctgtgcactcggcctccctggaggatgtg aagaccgcggtcctggggctcctggtcatccttcagaccaagctctataccttgcctgcc agccacgccactcgagtgtatgagagcctcattagtcacatccagctccattacaagcac ggctactccctgcccattgctagcagcatccggctgcaggcctttgacttcctgctgcta ctgcgggccgactcgctgcatcgactgggcctgcccaacaaggatggggtcgtgagattc agcccttactgcctctgtgactgcacggaactggatagagcctcagagaagaaagccagt gggcccctttcacctccaactgggccccctagccctgtgccaatgggccctgctgtgcga cttggccacctaccctactccctgctcttccgtgtcctgttgcagtgtttgaagcaggag agcgactggaaggtgctgaagctggtgctcagcaggctgccggagtcactacgctacaaa gtcctcatcttcacctccccctgcagtgtcgaccagctgtcttctgccctctgctccatg ctttcagctccaaagacccttgagcggctccgaggcaccccagaaggcttctcaagaact gacctgcacttggctgtggttcctgtgctaacagcattaatatcttatcacaactatttg gacaagaccagacagcgtgagatggtgtactgcctggaacaaggccttatctaccgctgc gccagccagtgcgtggtagccttggccatctgcagtgtggagatgcccgacatcatcatc aaggcgcttcctgtcctggtggtgaagctcacacacatttctgccacagccagcatggcc atcccgctcctggagttcctgtctactttggccaggctgccccacctctacaggaacttt gctgcagagcagtatgccagcgtgtttgccatctccttgccatacaccaacccctccaag ttcaaccagtacattgtgtgtctggctcaccatgtcatagccatgtggttcatcaggtgc cgactgccctttcggaaggatttcgtcccttatatcactaagggtctgcgttccaatgtc ctcctgtcttttgatgatacccctgagaaggacagtttcagagcacggagcaccagtctt aatgagagacccaaaagtttgaggatagccagagcccccaaacaaggcctgaataactct ccacctgtgaaagaattcaaagagagctgtgcagccgaggccttccggtgccgcagcatc agtgtatctgaacatgtggtccgcagcagaatacagacatcccttaccagcgccagcctg gggtctgcggatgagaactctatggcccaggctgatgacaacttgaagaatctccacttg gagctcacagaaacatgtctggacatgatggcccgatatgtgttctccaatttcactgca gtccccaagaggtcccctgtgggagagttcctcctggcagggggtaggaccaaaacctgg ctggttggaaacaagcttgtcactgtgacaacaagtgtgggaaccggtacacggtcgctg ctgggcctggactctggggacctgcagggtggctcagattcaagctctgatcctagcaca catgtgaggcagacaaaggaagcaccggctaaactggagtcccaggctgggcagcaggtg tcccgtggggcgcgggaccgggtccgctccatgtcggggggccatggccttcgagttggt gtcctggatacttcagctccctatcccccaagtggccctgcttctctgggaccacagacg gcggcagcagcgaagcccgagaagccccctgcaggagcccagcttccaacagcagagaag acaaatctggcagcctatgtgcctttgttgacccagggctgggcagaaatcttggtccgc agacccacaggaaacaccagctggctgatgagcttggagaacccgctcagccccttctcc tcagacatcaacaacatgcccctgcaagagctgtccaatgcccttatggctgctgaacgt ttcaaggagcaccgggacacggccctgtacaagtcattgtcagtgccagcggctggcacc gccaagcctcctactctcccacgctctaatacagtggcttctttctcctccctgtaccag cccagctgccaaggacagctgcacaggagcgtttcctgggcagactcggccatggtcctt gaggagggaagtctaggagagactcaggtgccagtggagccccccgaattggaggatttc gaggcggcattaggtacagacaggcactgccagcggcctgacacctacagccggtcatcc tcagcatctagccaggaagaaaagtcccatttggaggagcttgctgcagggggtatcccc attgagcgggccatctcctctgagggggctcggcctgccgtggacctctccttccaaccc tcacagcctttgagcaagtctagctcttctccggagttgcagaccttacaggacatcctt ggagacctaggggacaagactgatattggacggctgagtcctgaggctaaggtccggtcc cagtcagggatcctggatggggaagcagctacctggtcagctgcaggtgaagagagccgt atcacagtcccacctgaaggtcctctgccttccagttctccccgctcccccagtggcctc cggccccgaggctataccatctctgattctgctccatcacgaaggggaaagagggtagaa agggataacttcaagagcagagctgcggcctccagtgctgagaaggtgccaggcatcaac cctagctttgtgttcctacagctctaccattcgcccttttttggtgatgagtccaataag cccatcctgttgcccaatgagtcctttgaacggtcagtacagctgcttgaccagattcca tcctatgacactcacaagattgctgtcctgtatgtgggagaaggccagagcagcagtgag ctggccatcctgtcaaatgagcatggctcttacaggtacacggagtttctcacaggcctg ggtcgccttattgagctcaaggactgccaaccagacaaggtgtacttaggtggactggat gtatgtggcgaggatggacagttcacctactgctggcatgatgacatcatgcaagctgtt ttccacattgccaccctgatgcccaccaaggatgtggacaaacaccgctgtgacaaaaaa cggcacctgggcaatgactttgtttctatcatctacaatgattctggtgaggacttcaag ctgggcaccattaagggccagttcaactttgtccatgtgatcatcacaccgctggactac aagtgcaacctattgaccctgcagtgcaggaaagacatggagggcctcgtggacaccagc gtggccaagattgtgtctgaccgtaacctgtcctttgtggcccgacagatggccctgcat gcaaatatggcctcacaggtacaccacagccgatccaaccccactgacatctatccctcc aagtggatcgcaagacttcgccacattaagcgtctccgccagaggatccgtgaagaggtg cactattcaaacccaagcttgcctctgatgcaccctccagcccacaccaaagtcccagct caagcccctactgaggctacacccacctatgaaacaggccagcggaagcgcctcatttcc tccgtggatgacttcacagagtttgtgtga

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