KEGG   Mus caroli (Ryukyu mouse): 110284880
Entry
110284880         CDS       T05910                                 

Gene name
Pdgfrb
Definition
(RefSeq) platelet-derived growth factor receptor beta
  KO
K05089  platelet-derived growth factor receptor beta [EC:2.7.10.1]
Organism
mcal  Mus caroli (Ryukyu mouse)
Pathway
mcal01521  EGFR tyrosine kinase inhibitor resistance
mcal04010  MAPK signaling pathway
mcal04014  Ras signaling pathway
mcal04015  Rap1 signaling pathway
mcal04020  Calcium signaling pathway
mcal04072  Phospholipase D signaling pathway
mcal04151  PI3K-Akt signaling pathway
mcal04510  Focal adhesion
mcal04540  Gap junction
mcal04630  JAK-STAT signaling pathway
mcal04810  Regulation of actin cytoskeleton
mcal05165  Human papillomavirus infection
mcal05200  Pathways in cancer
mcal05206  MicroRNAs in cancer
mcal05214  Glioma
mcal05215  Prostate cancer
mcal05218  Melanoma
mcal05230  Central carbon metabolism in cancer
mcal05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:mcal00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    110284880 (Pdgfrb)
   04014 Ras signaling pathway
    110284880 (Pdgfrb)
   04015 Rap1 signaling pathway
    110284880 (Pdgfrb)
   04630 JAK-STAT signaling pathway
    110284880 (Pdgfrb)
   04020 Calcium signaling pathway
    110284880 (Pdgfrb)
   04072 Phospholipase D signaling pathway
    110284880 (Pdgfrb)
   04151 PI3K-Akt signaling pathway
    110284880 (Pdgfrb)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    110284880 (Pdgfrb)
   04540 Gap junction
    110284880 (Pdgfrb)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    110284880 (Pdgfrb)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    110284880 (Pdgfrb)
   05206 MicroRNAs in cancer
    110284880 (Pdgfrb)
   05230 Central carbon metabolism in cancer
    110284880 (Pdgfrb)
   05231 Choline metabolism in cancer
    110284880 (Pdgfrb)
  09162 Cancer: specific types
   05214 Glioma
    110284880 (Pdgfrb)
   05218 Melanoma
    110284880 (Pdgfrb)
   05215 Prostate cancer
    110284880 (Pdgfrb)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    110284880 (Pdgfrb)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    110284880 (Pdgfrb)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mcal01001]
    110284880 (Pdgfrb)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:mcal04090]
    110284880 (Pdgfrb)
Enzymes [BR:mcal01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     110284880 (Pdgfrb)
Protein kinases [BR:mcal01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   110284880 (Pdgfrb)
CD molecules [BR:mcal04090]
 Proteins
  110284880 (Pdgfrb)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase ig Ig_3 I-set Ig_2 V-set Ig_6
Other DBs
NCBI-GeneID: 110284880
NCBI-ProteinID: XP_021006487
Ensembl: MGP_CAROLIEiJ_G0022318
UniProt: A0A6P5NZ10
LinkDB
Position
18
AA seq 1098 aa
MGLSGVMPASVLRGQLLLSLLWLLGPQTSRGLVITPPGPEFVLNISSTFVLTCSSSAPVM
WEQMSQVPWQEAAMNQDGTFSSVLTLTNVTGGDTGEYFCVYNNSLGPELNERKRIYIFVP
DPTMGFLPMDSEDLFIFVTDVTETTIPCRVTDPQLEVTLHEKKVDIPLHVPYDHQRGFTG
TFEDKTYICKTTIGDREVDSDTYYVYSLQVSSINVSVNAVQTVVRQGESITIRCIVMGND
VVNFQWTYPRMKSGRLVEPVTDYLFGVPSRIGSILHIPTAELSDSGTYTCNVSVSVNDHG
DEKAINITVIENGYVRLLETLGDVEIAKLHRSRTLRVIFEAYPTPSVLWLKDNRTLGDSG
AGELVLSTRNVSETRYVSELTLVRVKVSEAGYYTMRVFHEDDEVQLSFKLQVNVPVRVLE
LSESHPANGEQIIRCRGRGMPQPNVTWSTCRDLKRCPRKLSPTPLGNSSKEESQLETNVT
FWEDDQEYEVVSTLRLRHVDQPLSVRCMLQNSMGGDSQEVTVVPHSLPFKVVVISAILAL
VVLTVISLIILIMLWQKKPRYEIRWKVIESVSSDGHEYIYVDPVQLPYDSTWELPRDQLV
LGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPH
LNVVNLLGACTKGGPIYIITEYCRYGDLVDYLHRNKHTFLQRHSNKHCPPSAELYSNALP
VGFSLPSHLNLTGESDGGYMDMSKDESVDYVPMLDMKGDIKYADIESSSYMAPYDNYVPS
APERTYRATLINDSPVLSYTDLVGFSYQVANGMDFLASKNCVHRDLAARNVLICEGKLVK
ICDFGLARDIMRDSNYISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGG
TPYPELPMNDQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFETRPPFSQLVLLLERL
LGEGYKKKYQQVDEEFLRSDHPAILRSQARFPGIHSLRSPLDTSSVLYTAVQPNESDNDY
IIPLPDPKPDAADEGLPEGSPSLASSTLNEANTSSTISCDSPLELQEEPQQAEPEAQLEQ
PQDSGCPEPLAEAEDSFL
NT seq 3297 nt   +upstreamnt  +downstreamnt
atgggactttcaggagtgatgccagcttcagtcctcagaggccagttgttgctgtccctg
ttatggctcctgggaccacagacctcccggggcctagtcatcacgccccctgggccagag
tttgtcctcaacatctccagcacctttgttctgacctgctcgagttcagctccggtgatg
tgggaacagatgtcccaggtgccctggcaagaagcagccatgaatcaggacggcaccttc
tccagtgtgctgacactgaccaatgtcactgggggagacactggggaatacttttgtgtc
tacaacaactcgctagggccggagctcaatgagaggaagcgtatctatatcttcgtgcca
gatcccaccatgggcttcctccctatggactccgaggacctgttcatttttgtcacggat
gtcactgagacgacaattccgtgccgagtgacagacccccagctggaggtaacgctacat
gagaagaaagtggacatccccctgcatgtaccctacgaccaccagcgaggtttcactggt
acttttgaggacaagacttacatttgcaaaaccaccattggggacagggaagtggactcc
gatacttactacgtctacagcctccaggtgtcatccatcaacgtctctgtgaatgccgtg
cagactgtggtccgccagggtgagagcatcaccatcaggtgcattgtgatgggcaatgat
gtggtgaacttccaatggacatacccccgcatgaagagtgggcggctggtggagccagtg
acagactacctctttggagtgccctcccgcattggctccatcctgcatatccccacggct
gagctgagtgattcgggcacctatacttgcaacgtgtcagtgagtgtgaacgaccatgga
gatgaaaaagccatcaacatcactgtgatcgagaatggctacgtgcggctgctggaaaca
ctgggagatgtagaaattgctaagctgcaccggagccggacgctgcgggtgatatttgag
gcttatccgacgccctctgtcctgtggctcaaggacaaccgtaccttgggcgactccggc
gctggcgagttagttctgtctactcgcaacgtgtctgagacccggtacgtgtcagaactg
accctggtacgtgtgaaggtgtcagaagcgggctactatactatgcgagtcttccacgag
gacgatgaggtccagctctccttcaagctgcaggtcaatgtccccgtccgtgtgctggag
ctgagtgagagtcaccctgccaatggggagcagataatccgctgtcgtggccggggcatg
cctcagccaaatgtcacctggtctacctgcagagacctcaaaaggtgtccacgaaaactg
tcacccacacccttggggaatagttccaaggaggagagccagctagaaacgaatgtgact
ttctgggaggacgatcaggaatacgaggtggtgagcacactgcgtctgcgccacgtggat
cagccactgtccgtacgctgcatgctgcagaactccatgggcggagattcgcaggaggtc
accgtggtcccacattccttgcccttcaaagtggtggtgatctcagccatcctggcctta
gtggtccttaccgtcatctctctcatcatcctcatcatgctgtggcagaagaagccacgc
tatgagatccgatggaaggtcattgagtctgtgagctctgacggtcatgagtacatctac
gtggaccctgtgcagttgccttacgactccacgtgggagctgccacgggaccagcttgtt
ctgggacgcactcttggctctggggctttcggacaggtggtggaggccacggctcacggt
ctgagccattcgcaggccaccatgaaagtggctgtcaagatgctgaaatcaacagccaga
agtagcgagaagcaagccttaatgtcggagctgaagattatgagtcaccttggaccccac
ctgaacgtggtcaacctgctgggggcctgcaccaaaggagggcccatctacatcatcacg
gaatactgccgctacggtgacctggtggactatctgcaccggaacaaacacaccttcttg
cagcgacactccaacaagcattgtccgccaagtgctgagctctacagcaacgccctgcca
gtggggttctccctacccagccacttgaacctgactggggagagtgacggtggctacatg
gatatgagcaaggatgaatctgtagattacgtgcccatgttggacatgaaaggagacatc
aaatatgcagacattgagtcctccagctacatggccccttatgataactatgtcccatct
gcccctgaaaggacctatcgtgccaccttaatcaacgactcaccagtgctcagctacaca
gacctcgtgggcttcagctaccaagtggccaacggcatggacttcttagcctctaagaac
tgtgttcaccgagacttggcggccaggaatgtgctcatctgcgagggcaagctggtcaag
atctgtgactttggcctggctcgagacatcatgagggactcaaactacatctccaaaggc
agtacctttctgcctctgaagtggatggccccagagagcatcttcaacagcctctacacc
accttgagtgatgtgtggtcttttgggatcctactctgggagatcttcacactgggtggt
accccttacccagagctgcccatgaacgaccagttttacaatgccatcaagaggggctac
cgcatggcccagcctgctcatgcctcggatgagatctatgagatcatgcagaaatgctgg
gaagaaaagtttgagactcgaccccccttctcccagctggtgctgctcctggagaggctt
ctgggtgaaggctataaaaagaaataccagcaggtagacgaggagttcctgaggagtgac
catccggccatcctgaggtcccaagcccgctttccggggatccacagcctccgatcccct
ctggacaccagctctgttctctacactgccgtgcagcccaatgagagtgacaatgactac
atcatccccttacctgaccccaagcctgacgctgctgatgaaggtctcccagaggggtcc
cccagccttgccagttccaccttgaatgaagccaacacttcctccaccatctcctgcgac
agtcccctggagctccaagaagagccacagcaagcagagcctgaggcacaactggagcag
ccacaggattcaggctgcccagaacctctggctgaagcagaggacagcttcctgtag

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