Mus caroli (Ryukyu mouse): 110292243
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Entry
110292243 CDS
T05910
Gene name
Jak1
Definition
(RefSeq) tyrosine-protein kinase JAK1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
mcal
Mus caroli (Ryukyu mouse)
Pathway
mcal01521
EGFR tyrosine kinase inhibitor resistance
mcal04151
PI3K-Akt signaling pathway
mcal04217
Necroptosis
mcal04380
Osteoclast differentiation
mcal04550
Signaling pathways regulating pluripotency of stem cells
mcal04621
NOD-like receptor signaling pathway
mcal04630
JAK-STAT signaling pathway
mcal04658
Th1 and Th2 cell differentiation
mcal04659
Th17 cell differentiation
mcal05140
Leishmaniasis
mcal05145
Toxoplasmosis
mcal05152
Tuberculosis
mcal05160
Hepatitis C
mcal05161
Hepatitis B
mcal05162
Measles
mcal05163
Human cytomegalovirus infection
mcal05164
Influenza A
mcal05165
Human papillomavirus infection
mcal05166
Human T-cell leukemia virus 1 infection
mcal05167
Kaposi sarcoma-associated herpesvirus infection
mcal05168
Herpes simplex virus 1 infection
mcal05169
Epstein-Barr virus infection
mcal05171
Coronavirus disease - COVID-19
mcal05200
Pathways in cancer
mcal05203
Viral carcinogenesis
mcal05212
Pancreatic cancer
mcal05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mcal00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
110292243 (Jak1)
04151 PI3K-Akt signaling pathway
110292243 (Jak1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
110292243 (Jak1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
110292243 (Jak1)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
110292243 (Jak1)
04658 Th1 and Th2 cell differentiation
110292243 (Jak1)
04659 Th17 cell differentiation
110292243 (Jak1)
09158 Development and regeneration
04380 Osteoclast differentiation
110292243 (Jak1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110292243 (Jak1)
05203 Viral carcinogenesis
110292243 (Jak1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
110292243 (Jak1)
09162 Cancer: specific types
05212 Pancreatic cancer
110292243 (Jak1)
09171 Infectious disease: bacterial
05152 Tuberculosis
110292243 (Jak1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
110292243 (Jak1)
05161 Hepatitis B
110292243 (Jak1)
05160 Hepatitis C
110292243 (Jak1)
05171 Coronavirus disease - COVID-19
110292243 (Jak1)
05164 Influenza A
110292243 (Jak1)
05162 Measles
110292243 (Jak1)
05168 Herpes simplex virus 1 infection
110292243 (Jak1)
05163 Human cytomegalovirus infection
110292243 (Jak1)
05167 Kaposi sarcoma-associated herpesvirus infection
110292243 (Jak1)
05169 Epstein-Barr virus infection
110292243 (Jak1)
05165 Human papillomavirus infection
110292243 (Jak1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
110292243 (Jak1)
05140 Leishmaniasis
110292243 (Jak1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
110292243 (Jak1)
Enzymes [BR:
mcal01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
110292243 (Jak1)
Protein kinases [BR:
mcal01001
]
Non-receptor tyrosine kinases
JAK family [OT]
110292243 (Jak1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
FERM_F1
RIO1
SH2
Motif
Other DBs
NCBI-GeneID:
110292243
NCBI-ProteinID:
XP_021015091
Ensembl:
MGP_CAROLIEiJ_G0026203
UniProt:
A0A6P5PK49
LinkDB
All DBs
Position
4
AA seq
1153 aa
AA seq
DB search
MQYLNIKEDCNAMAFCAKMRSFKKTEVKQVVPEPGVEVTFYLLDREPLRLGSGEYTAEEL
CIRAAQECSISPLCHNLFALYDESTKLWYAPNRIITVDDKMSLRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKNGYEKKRVPEATPLLDASSLEYLFAQGQYDLIKCLAPIRDPKTEQ
DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENELS
RCHSNDSGNVLYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLEYNKHKKDDERNKLR
EEWNNFSYFPEITHIVIKESVVSINKQDNKNMELKLSSHEEALSFVSLVDGYFRLTADAH
HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
CFEKSEVLGGQKQFKNFQIEVQKGRYSLHGSMDHFPSLRDLMNHLKKQILRTDNISFVLK
RCCQPKPREISNLLVATKKAQEWQPVYSMSQLSFDRILKKDIIQGEHLGRGTRTHIYSGT
LLDYKDEEGIAEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV
ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL
LAREGIDSDIGPFIKLSDPGIPVSVLTRQECIERIPWIAPECVEDSKNLSVAADKWSFGT
TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI
MRDINKLEEQNPDIVSEKQPTTEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT
GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICMEDGGNGIKLIMEFLPS
GSLKEYLPKNKNKINLKQQLKYAIQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD
FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD
FSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTT
FQSLIEGFEALLK
NT seq
3462 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatctaaatataaaagaggactgcaatgccatggcgttctgtgctaaaatgagg
agcttcaagaagactgaggtgaagcaggtggtccctgagccaggagtggaggtgactttc
tatctgttggacagggagcccctccgcctgggcagcggagagtatacagccgaggagctg
tgcatcagggccgcccaggagtgcagtatctctcctctctgtcacaacctcttcgccctg
tatgatgagagcaccaagctctggtacgctccgaaccgaatcatcactgtggatgacaaa
atgtctctccggctccactaccgcatgaggttctactttaccaactggcacggaaccaat
gacaacgaacagtctgtgtggcgacattctccaaagaagcagaaaaacggctatgagaag
aaaagggttccagaagcaaccccactccttgatgccagttcactggagtatctgtttgca
cagggacagtatgatttgatcaaatgcctggctcccattcgggaccccaagacggagcaa
gacggacatgatattgagaatgagtgcctgggcatggcggtcctggccatctcccactat
gccatgatgaagaagatgcagttgccggaacttcccaaagacatcagctacaagcgatat
attccagaaacattgaataaatccatcagacagaggaacctccttaccaggatgcgaata
aataatgttttcaaggatttcttgaaggaatttaacaacaagaccatctgtgacagcagt
gtgtctacacatgacctgaaggtgaaatacctggctaccttggaaactttgacaaaacat
tatggagctgaaatatttgagacttctatgctactgatatcatcagaaaatgaattgagt
cggtgccattcgaatgacagtggcaatgttctctatgaagtcatggtgactggaaatctc
gggatccagtggcggcagaaaccaaatgttgttcctgttgaaaaggaaaaaaataaactg
aagcggaaaaaactggaatataataaacacaagaaggatgatgagagaaacaaactccgg
gaagagtggaacaatttttcctatttccctgaaatcacccatattgtaataaaggagtct
gtggtcagcattaacaaacaggacaacaaaaacatggaactcaagctctcttctcacgag
gaagccttgtcctttgtgtccctggtggatggctacttccggctcactgcagatgcccac
cattacctctgtactgatgtggctcccccactgattgtccacaatatacagaacggctgt
cacggtccaatctgcacagagtatgccatcaataagctgcggcaggaagggagtgaagag
gggatgtacgtgctgaggtggagctgcactgactttgacaacattcttatgactgtcacc
tgctttgagaagtctgaggtattgggtggccagaagcagttcaagaactttcagattgag
gtacagaagggccgctacagcctgcatggctctatggaccactttcccagcctgcgagac
ctcatgaaccacctcaagaagcagatcctgcgcacggacaacataagctttgtgctgaaa
cgatgctgccagcctaagcctcgagaaatctccaatctgctcgtagccactaagaaagcc
caggagtggcagcctgtctactccatgagccagctgagctttgatcggatccttaagaaa
gatattatacaaggtgagcaccttggcagaggcacaagaacacatatctattctgggacc
ctgctggactacaaggatgaggaaggaattgctgaagagaagaagataaaagtgatcctc
aaagtcctagaccccagccaccgggacatttctctggccttctttgaggcagctagcatg
atgagacaagtttctcataaacacattgtgtacctctacggcgtgtgtgtccgagacgtg
gagaatatcatggtggaagagtttgtggagggggggccattggatctcttcatgcaccgg
aaaagtgatgtgcttactaccccctggaagttcaaggttgccaaacagctggccagtgcc
ctgagttacttggaagataaagacctggtccatggaaatgtgtgcactaaaaacctgctt
ctggcccgagagggcattgacagtgacattggcccgttcatcaagcttagtgaccctggc
atcccagtctctgtgctgaccaggcaagagtgcatagagcgaatcccctggatcgctcct
gagtgtgttgaagactccaagaacctgagtgtggctgctgacaagtggagctttggcacc
acactctgggaaatctgctacaatggagagattcctctcaaagacaagaccctcattgag
aaagagaggttttatgaaagccgctgcaggcctgtgactccatcttgcaaggagctagct
gacctcatgactcgctgcatgaactatgatcccaaccagagacccttcttccgagccatc
atgagggacattaacaagctggaggagcagaatccagacattgtttcagaaaagcagcca
acaacagaggtggaccccactcactttgaaaagcggttcctgaaaaggattcgtgacttg
ggagagggtcactttgggaaggttgagctctgcagatatgatcctgagggagacaacaca
ggggaacaggtagctgtcaagtccctgaagcctgagagtggaggtaaccacatagctgat
ctgaagaaggagatagagatcttacggaacctgtaccatgagaacattgtgaagtacaaa
ggaatctgcatggaagacggaggcaatggtatcaagctcatcatggagtttctgccttcg
gggagcctaaaggaatatctgccaaagaataagaacaaaatcaacctcaaacagcagcta
aaatacgccatccagatttgtaaggggatggactatttgggttctcggcaatacgttcac
cgggacttagcagcaagaaatgtccttgttgagagtgagcatcaagtgaagatcggagac
tttggtttaaccaaagcaattgaaaccgataaggagtactacacagtcaaggacgaccgg
gacagcccagtgttctggtacgctccggaatgtttaatccagtgtaaattttatatcgcc
tctgatgtctggtcttttggagtgacactgcacgagctgctcacttactgtgactcagat
tttagtcctatggccttgttcctgaaaatgataggcccaactcatggccagatgacagta
acgcggcttgtgaatactctgaaagaagggaagcgtctgccatgtccacccaactgtcct
gatgaggtttatcagctcatgagaaaatgctgggaattccaaccatctaaccggactact
tttcagagcctcattgaaggatttgaagcacttttaaaataa
DBGET
integrated database retrieval system
