Mus caroli (Ryukyu mouse): 110295945
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Entry
110295945 CDS
T05910
Gene name
Braf
Definition
(RefSeq) serine/threonine-protein kinase B-raf isoform X1
KO
K04365
B-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
mcal
Mus caroli (Ryukyu mouse)
Pathway
mcal01521
EGFR tyrosine kinase inhibitor resistance
mcal01522
Endocrine resistance
mcal04010
MAPK signaling pathway
mcal04012
ErbB signaling pathway
mcal04015
Rap1 signaling pathway
mcal04024
cAMP signaling pathway
mcal04062
Chemokine signaling pathway
mcal04068
FoxO signaling pathway
mcal04150
mTOR signaling pathway
mcal04270
Vascular smooth muscle contraction
mcal04510
Focal adhesion
mcal04650
Natural killer cell mediated cytotoxicity
mcal04720
Long-term potentiation
mcal04722
Neurotrophin signaling pathway
mcal04726
Serotonergic synapse
mcal04730
Long-term depression
mcal04810
Regulation of actin cytoskeleton
mcal04910
Insulin signaling pathway
mcal04914
Progesterone-mediated oocyte maturation
mcal04928
Parathyroid hormone synthesis, secretion and action
mcal04934
Cushing syndrome
mcal05010
Alzheimer disease
mcal05022
Pathways of neurodegeneration - multiple diseases
mcal05034
Alcoholism
mcal05160
Hepatitis C
mcal05161
Hepatitis B
mcal05200
Pathways in cancer
mcal05205
Proteoglycans in cancer
mcal05210
Colorectal cancer
mcal05211
Renal cell carcinoma
mcal05212
Pancreatic cancer
mcal05213
Endometrial cancer
mcal05214
Glioma
mcal05215
Prostate cancer
mcal05216
Thyroid cancer
mcal05218
Melanoma
mcal05219
Bladder cancer
mcal05220
Chronic myeloid leukemia
mcal05221
Acute myeloid leukemia
mcal05223
Non-small cell lung cancer
mcal05224
Breast cancer
mcal05225
Hepatocellular carcinoma
mcal05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
mcal00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110295945 (Braf)
04012 ErbB signaling pathway
110295945 (Braf)
04015 Rap1 signaling pathway
110295945 (Braf)
04068 FoxO signaling pathway
110295945 (Braf)
04024 cAMP signaling pathway
110295945 (Braf)
04150 mTOR signaling pathway
110295945 (Braf)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
110295945 (Braf)
09142 Cell motility
04810 Regulation of actin cytoskeleton
110295945 (Braf)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
110295945 (Braf)
04062 Chemokine signaling pathway
110295945 (Braf)
09152 Endocrine system
04910 Insulin signaling pathway
110295945 (Braf)
04914 Progesterone-mediated oocyte maturation
110295945 (Braf)
04928 Parathyroid hormone synthesis, secretion and action
110295945 (Braf)
09153 Circulatory system
04270 Vascular smooth muscle contraction
110295945 (Braf)
09156 Nervous system
04726 Serotonergic synapse
110295945 (Braf)
04720 Long-term potentiation
110295945 (Braf)
04730 Long-term depression
110295945 (Braf)
04722 Neurotrophin signaling pathway
110295945 (Braf)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110295945 (Braf)
05205 Proteoglycans in cancer
110295945 (Braf)
09162 Cancer: specific types
05210 Colorectal cancer
110295945 (Braf)
05212 Pancreatic cancer
110295945 (Braf)
05225 Hepatocellular carcinoma
110295945 (Braf)
05226 Gastric cancer
110295945 (Braf)
05214 Glioma
110295945 (Braf)
05216 Thyroid cancer
110295945 (Braf)
05221 Acute myeloid leukemia
110295945 (Braf)
05220 Chronic myeloid leukemia
110295945 (Braf)
05218 Melanoma
110295945 (Braf)
05211 Renal cell carcinoma
110295945 (Braf)
05219 Bladder cancer
110295945 (Braf)
05215 Prostate cancer
110295945 (Braf)
05213 Endometrial cancer
110295945 (Braf)
05224 Breast cancer
110295945 (Braf)
05223 Non-small cell lung cancer
110295945 (Braf)
09164 Neurodegenerative disease
05010 Alzheimer disease
110295945 (Braf)
05022 Pathways of neurodegeneration - multiple diseases
110295945 (Braf)
09165 Substance dependence
05034 Alcoholism
110295945 (Braf)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
110295945 (Braf)
09172 Infectious disease: viral
05161 Hepatitis B
110295945 (Braf)
05160 Hepatitis C
110295945 (Braf)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
110295945 (Braf)
01522 Endocrine resistance
110295945 (Braf)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcal01001
]
110295945 (Braf)
Enzymes [BR:
mcal01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
110295945 (Braf)
Protein kinases [BR:
mcal01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
110295945 (Braf)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
Pkinase_fungal
C1_2
APH
Kdo
Motif
Other DBs
NCBI-GeneID:
110295945
NCBI-ProteinID:
XP_021020018
Ensembl:
MGP_CAROLIEiJ_G0028251
LinkDB
All DBs
Position
6
AA seq
764 aa
AA seq
DB search
MAALSGGGGSSSGGGGGGGGGGGGGDGGGGAEQGQALFNGDMEPEAGAGAAASSAADPAI
PEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESL
VFQTPTDVSRNNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCA
VYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLF
QGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPVPQEEASLPETALPSGS
SSAPPSDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPV
NIDEKFPEVELQDQRDLIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKALQKSPGPQRE
RKSSSSSSSEDRSRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVK
MLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHI
IETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSR
WSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRD
QIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPK
IHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGEFAAFK
NT seq
2295 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgctgagtggcggcggtggcagcagcagcggtggcggcggcggcggtggcggc
ggcggtggcggtggcgacggcggcggcggcgccgagcagggccaggctctgttcaatggc
gacatggagccggaggccggcgctggcgccgcggcctcttcggctgcggacccggccatt
cctgaagaggtatggaatatcaagcaaatgattaagttgacacaggaacatatagaggcc
ctattggacaaatttggtggagagcataacccaccatcaatatacctggaggcctatgaa
gagtacaccagcaagctagatgcccttcagcaaagagaacagcagcttttggaatccctg
gtttttcaaactcccacagatgtatcacggaacaaccccaagtcaccacagaaacctatc
gttagagtcttcctgcccaacaaacagagaacagtggtacctgcaagatgtggtgttaca
gttcgagacagtctaaagaaagcactgatgatgagaggtctcatcccagaatgctgtgct
gtttacagaattcaggatggagagaagaaaccaattggctgggacacggacatttcctgg
cttactggagaggagttacatgttgaagtactagagaatgttccacttacaacacacaac
tttgtacggaaaacttttttcaccttagcattttgtgacttttgccgaaagctgcttttc
cagggtttccgttgtcaaacatgtggttataaatttcaccagcgttgtagtacagaggtt
ccactgatgtgtgtaaattatgaccaacttgatttgctgtttgtctccaagttctttgag
catcacccagtaccacaggaggaggcctccttaccagagactgcccttccatctggatcc
tcttccgcacccccctcagactctattgggccccaaatcctcaccagtccatctccttca
aaatccattccaattccacagcccttccgaccagcagatgaagatcatcgcaatcagttt
gggcaacgagaccggtcctcctcagctcctaatgttcatataaacacaattgagcctgtc
aatatcgatgaaaaattcccagaagtggaattacaggatcaaagggatttgattagagac
caggggtttcgtggtgatggagggtcaaccacaggcttgtccgccaccccgcctgcctca
ttacctggctcactcactaacgtgaaagccttacagaaatctccaggtcctcagcgggaa
aggaagtcgtcttcttcctcatcctcggaggacagaagtcggatgaaaacacttggtaga
agagattcaagtgatgactgggagattcctgatggacagattacagtgggacagagaatt
ggatctgggtcatttggaactgtctacaagggaaagtggcatggtgatgtggcagtgaaa
atgttgaatgtgacagcacccacacctcaacagttacaggccttcaaaaatgaagtagga
gtactcaggaaaactcgacatgtgaacatcctccttttcatgggctattctacaaagcca
caactggcaattgttacacagtggtgtgagggctccagcttatatcaccatctccacatc
attgagaccaaatttgagatgatcaaacttatagatattgctcggcagactgcacagggc
atggattacttacacgccaagtcaatcatccacagagacctcaagagtaataatatattt
cttcatgaagacctcacggtaaaaataggtgactttggtctagccacagtgaaatctcgg
tggagtgggtcccatcagtttgaacagttgtctggatctattttgtggatggcaccagaa
gtaatcagaatgcaagataagaacccgtatagctttcagtcagatgtgtatgcattcggg
attgtgctgtatgaactgatgactggccagctaccttattcaaacatcaacaacagggac
cagataatttttatggtgggacgaggatacctatccccagatctcagtaaggtacggagt
aactgtccaaaagccatgaagagattaatggcagagtgcctcaaaaagaaaagagacgag
agaccactctttccccaaattctcgcctccattgagctgctggcccgctcattgccaaaa
attcaccgcagtgcatcagaaccctccttgaatcgggctggtttccaaacagaagatttt
agtctgtatgcttgtgcttctccgaaaacacccatccaagcagggggatatggagaattt
gcagccttcaagtag
DBGET
integrated database retrieval system
