Mus caroli (Ryukyu mouse): 110296194 Help Entry 110296194         CDS       T05910                                  Gene name Kras Definition (RefSeq) GTPase KRas isoform X1   KO K07827   GTPase KRas Organism mcal  Mus caroli (Ryukyu mouse) Pathway mcal01521   EGFR tyrosine kinase inhibitor resistance mcal01522   Endocrine resistance mcal04010   MAPK signaling pathway mcal04012   ErbB signaling pathway mcal04014   Ras signaling pathway mcal04015   Rap1 signaling pathway mcal04062   Chemokine signaling pathway mcal04068   FoxO signaling pathway mcal04071   Sphingolipid signaling pathway mcal04072   Phospholipase D signaling pathway mcal04137   Mitophagy - animal mcal04140   Autophagy - animal mcal04150   mTOR signaling pathway mcal04151   PI3K-Akt signaling pathway mcal04210   Apoptosis mcal04211   Longevity regulating pathway mcal04213   Longevity regulating pathway - multiple species mcal04218   Cellular senescence mcal04360   Axon guidance mcal04370   VEGF signaling pathway mcal04371   Apelin signaling pathway mcal04540   Gap junction mcal04550   Signaling pathways regulating pluripotency of stem cells mcal04625   C-type lectin receptor signaling pathway mcal04650   Natural killer cell mediated cytotoxicity mcal04660   T cell receptor signaling pathway mcal04662   B cell receptor signaling pathway mcal04664   Fc epsilon RI signaling pathway mcal04714   Thermogenesis mcal04720   Long-term potentiation mcal04722   Neurotrophin signaling pathway mcal04725   Cholinergic synapse mcal04726   Serotonergic synapse mcal04730   Long-term depression mcal04810   Regulation of actin cytoskeleton mcal04910   Insulin signaling pathway mcal04912   GnRH signaling pathway mcal04914   Progesterone-mediated oocyte maturation mcal04915   Estrogen signaling pathway mcal04916   Melanogenesis mcal04917   Prolactin signaling pathway mcal04919   Thyroid hormone signaling pathway mcal04921   Oxytocin signaling pathway mcal04926   Relaxin signaling pathway mcal04929   GnRH secretion mcal04933   AGE-RAGE signaling pathway in diabetic complications mcal04935   Growth hormone synthesis, secretion and action mcal04960   Aldosterone-regulated sodium reabsorption mcal05010   Alzheimer disease mcal05022   Pathways of neurodegeneration - multiple diseases mcal05034   Alcoholism mcal05160   Hepatitis C mcal05161   Hepatitis B mcal05163   Human cytomegalovirus infection mcal05165   Human papillomavirus infection mcal05166   Human T-cell leukemia virus 1 infection mcal05167   Kaposi sarcoma-associated herpesvirus infection mcal05170   Human immunodeficiency virus 1 infection mcal05200   Pathways in cancer mcal05203   Viral carcinogenesis mcal05205   Proteoglycans in cancer mcal05206   MicroRNAs in cancer mcal05210   Colorectal cancer mcal05211   Renal cell carcinoma mcal05212   Pancreatic cancer mcal05213   Endometrial cancer mcal05214   Glioma mcal05215   Prostate cancer mcal05216   Thyroid cancer mcal05218   Melanoma mcal05219   Bladder cancer mcal05220   Chronic myeloid leukemia mcal05221   Acute myeloid leukemia mcal05223   Non-small cell lung cancer mcal05224   Breast cancer mcal05225   Hepatocellular carcinoma mcal05226   Gastric cancer mcal05230   Central carbon metabolism in cancer mcal05231   Choline metabolism in cancer mcal05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:mcal00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     110296194 (Kras)    04012 ErbB signaling pathway     110296194 (Kras)    04014 Ras signaling pathway     110296194 (Kras)    04015 Rap1 signaling pathway     110296194 (Kras)    04370 VEGF signaling pathway     110296194 (Kras)    04371 Apelin signaling pathway     110296194 (Kras)    04068 FoxO signaling pathway     110296194 (Kras)    04072 Phospholipase D signaling pathway     110296194 (Kras)    04071 Sphingolipid signaling pathway     110296194 (Kras)    04151 PI3K-Akt signaling pathway     110296194 (Kras)    04150 mTOR signaling pathway     110296194 (Kras)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     110296194 (Kras)    04137 Mitophagy - animal     110296194 (Kras)   09143 Cell growth and death    04210 Apoptosis     110296194 (Kras)    04218 Cellular senescence     110296194 (Kras)   09144 Cellular community - eukaryotes    04540 Gap junction     110296194 (Kras)    04550 Signaling pathways regulating pluripotency of stem cells     110296194 (Kras)   09142 Cell motility    04810 Regulation of actin cytoskeleton     110296194 (Kras)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     110296194 (Kras)    04650 Natural killer cell mediated cytotoxicity     110296194 (Kras)    04660 T cell receptor signaling pathway     110296194 (Kras)    04662 B cell receptor signaling pathway     110296194 (Kras)    04664 Fc epsilon RI signaling pathway     110296194 (Kras)    04062 Chemokine signaling pathway     110296194 (Kras)   09152 Endocrine system    04910 Insulin signaling pathway     110296194 (Kras)    04929 GnRH secretion     110296194 (Kras)    04912 GnRH signaling pathway     110296194 (Kras)    04915 Estrogen signaling pathway     110296194 (Kras)    04914 Progesterone-mediated oocyte maturation     110296194 (Kras)    04917 Prolactin signaling pathway     110296194 (Kras)    04921 Oxytocin signaling pathway     110296194 (Kras)    04926 Relaxin signaling pathway     110296194 (Kras)    04935 Growth hormone synthesis, secretion and action     110296194 (Kras)    04919 Thyroid hormone signaling pathway     110296194 (Kras)    04916 Melanogenesis     110296194 (Kras)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     110296194 (Kras)   09156 Nervous system    04725 Cholinergic synapse     110296194 (Kras)    04726 Serotonergic synapse     110296194 (Kras)    04720 Long-term potentiation     110296194 (Kras)    04730 Long-term depression     110296194 (Kras)    04722 Neurotrophin signaling pathway     110296194 (Kras)   09158 Development and regeneration    04360 Axon guidance     110296194 (Kras)   09149 Aging    04211 Longevity regulating pathway     110296194 (Kras)    04213 Longevity regulating pathway - multiple species     110296194 (Kras)   09159 Environmental adaptation    04714 Thermogenesis     110296194 (Kras)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     110296194 (Kras)    05206 MicroRNAs in cancer     110296194 (Kras)    05205 Proteoglycans in cancer     110296194 (Kras)    05203 Viral carcinogenesis     110296194 (Kras)    05230 Central carbon metabolism in cancer     110296194 (Kras)    05231 Choline metabolism in cancer     110296194 (Kras)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     110296194 (Kras)   09162 Cancer: specific types    05210 Colorectal cancer     110296194 (Kras)    05212 Pancreatic cancer     110296194 (Kras)    05225 Hepatocellular carcinoma     110296194 (Kras)    05226 Gastric cancer     110296194 (Kras)    05214 Glioma     110296194 (Kras)    05216 Thyroid cancer     110296194 (Kras)    05221 Acute myeloid leukemia     110296194 (Kras)    05220 Chronic myeloid leukemia     110296194 (Kras)    05218 Melanoma     110296194 (Kras)    05211 Renal cell carcinoma     110296194 (Kras)    05219 Bladder cancer     110296194 (Kras)    05215 Prostate cancer     110296194 (Kras)    05213 Endometrial cancer     110296194 (Kras)    05224 Breast cancer     110296194 (Kras)    05223 Non-small cell lung cancer     110296194 (Kras)   09164 Neurodegenerative disease    05010 Alzheimer disease     110296194 (Kras)    05022 Pathways of neurodegeneration - multiple diseases     110296194 (Kras)   09165 Substance dependence    05034 Alcoholism     110296194 (Kras)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     110296194 (Kras)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     110296194 (Kras)    05170 Human immunodeficiency virus 1 infection     110296194 (Kras)    05161 Hepatitis B     110296194 (Kras)    05160 Hepatitis C     110296194 (Kras)    05163 Human cytomegalovirus infection     110296194 (Kras)    05167 Kaposi sarcoma-associated herpesvirus infection     110296194 (Kras)    05165 Human papillomavirus infection     110296194 (Kras)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     110296194 (Kras)    01522 Endocrine resistance     110296194 (Kras)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mcal04131]     110296194 (Kras)   09183 Protein families: signaling and cellular processes    04031 GTP-binding proteins [BR:mcal04031]     110296194 (Kras) Membrane trafficking [BR:mcal04131]  Endocytosis   Macropinocytosis    Ras GTPases     110296194 (Kras) GTP-binding proteins [BR:mcal04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     110296194 (Kras) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 G-alpha FeoB_N ATP_bind_1 Gtr1_RagA Septin CbiA ParA AAA_25 Motif Other DBs NCBI-GeneID:  110296194 NCBI-ProteinID:  XP_021020441 Ensembl:  MGP_CAROLIEiJ_G0029047 UniProt:  A0A6P5PQ68 LinkDB All DBs Position 6 AA seq 189 aa AA seqDB search MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL PSRTVDTKQAQELARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGC VKIKKCVIM NT seq 570 nt NT seq  +upstreamnt  +downstreamnt atgactgagtataaacttgtggtagttggagctggtggcgtaggcaagagtgccttgacg atacagctaattcagaatcactttgtggatgaatatgatcctacgatagaggactcctac aggaaacaagtagtaattgatggagaaacctgtctcttggatattctcgacacagcaggt caagaggagtacagtgcaatgagggaccagtacatgagaactggggagggctttctttgt gtatttgccataaataatactaaatcatttgaagatattcaccattatagagaacaaatt aaaagagtaaaggactctgaagatgtgcctatggtcctggtagggaataagtgtgatttg ccttctagaacagtagacacgaaacaggctcaggagttagcaaggagttacgggattccg ttcattgagacctcagcaaagacaagacagagagtggaggatgctttttatacattggtg agagagatccgacagtacagattgaaaaaaatcagcaaagaagaaaagactcctggctgt gtgaaaattaaaaaatgcgttataatgtaa

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